Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

CACNA1A CACNA1B CACNA1E

9.52e-079463GO:0099511
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

CACNA1A CACNA1B CACNA1E

9.52e-079463GO:0099626
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1A CACNA1B CACNA1E RYR1

3.75e-0646464GO:0005245
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1A CACNA1B CACNA1E

4.09e-0614463GO:0008331
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA1A KCNK5 CACNA1B CACNA1E RYR1

2.55e-05152465GO:0022843
GeneOntologyMolecularFunctionRNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity

NANOGP8 NANOG

3.11e-054462GO:0001010
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1A KCNK5 CACNA1B CACNA1E RYR1

6.03e-05182465GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1A KCNK5 CACNA1B CACNA1E RYR1

6.35e-05184465GO:0022832
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1A KCNK5 CACNA1B CACNA1E RYR1 SCN4A

1.29e-04343466GO:0005261
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1A CACNA1B CACNA1E RYR1

2.20e-04129464GO:0005262
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1A CACNA1B CACNA1E RYR1

4.01e-04151464GO:0015085
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1A KCNK5 CACNA1B CACNA1E RYR1 SCN4A

6.14e-04459466GO:0005216
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1A KCNK5 CACNA1B CACNA1E RYR1 SCN4A

6.57e-04465466GO:0046873
GeneOntologyMolecularFunctiongated channel activity

CACNA1A KCNK5 CACNA1B CACNA1E RYR1

9.93e-04334465GO:0022836
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

HELZ2 FGA NIPSNAP2 NANOGP8 TIAL1 NANOG HNRNPU NIPSNAP1 TNRC6A

1.15e-031160469GO:0030674
GeneOntologyMolecularFunctionchannel activity

CACNA1A KCNK5 CACNA1B CACNA1E RYR1 SCN4A

1.23e-03525466GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1A KCNK5 CACNA1B CACNA1E RYR1 SCN4A

1.24e-03526466GO:0022803
GeneOntologyMolecularFunctioncalcium ion binding

CACNA1B CACNA1E MAN1A1 CANT1 LRP1B UNC13A RYR1

1.52e-03749467GO:0005509
GeneOntologyMolecularFunctioncalmodulin binding

CACNA1A CEACAM5 UNC13A RYR1

1.92e-03230464GO:0005516
GeneOntologyMolecularFunctionmRNA 3'-UTR AU-rich region binding

TIA1 TIAL1

2.03e-0329462GO:0035925
GeneOntologyMolecularFunctionpoly(A) binding

TIA1 HNRNPU

2.03e-0329462GO:0008143
GeneOntologyMolecularFunctionlysine-acetylated histone binding

NANOGP8 NANOG

2.17e-0330462GO:0070577
GeneOntologyMolecularFunctionacetylation-dependent protein binding

NANOGP8 NANOG

2.31e-0331462GO:0140033
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CACNA1A KCNK5 CACNA1B CACNA1E RYR1 SCN4A

3.01e-03627466GO:0022890
GeneOntologyMolecularFunctionpoly-purine tract binding

TIA1 HNRNPU

3.28e-0337462GO:0070717
GeneOntologyMolecularFunctionmolecular adaptor activity

HELZ2 FGA NIPSNAP2 NANOGP8 TIAL1 NANOG HNRNPU NIPSNAP1 TNRC6A

3.35e-031356469GO:0060090
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1A KCNK5 CACNA1B CACNA1E RYR1 SCN4A

3.99e-03664466GO:0008324
GeneOntologyBiologicalProcessnegative regulation of endodermal cell fate specification

NANOGP8 NANOG

2.78e-054452GO:0042664
GeneOntologyBiologicalProcessregulation of endodermal cell fate specification

NANOGP8 NANOG

4.63e-055452GO:0042663
GeneOntologyBiologicalProcessnegative regulation of stem cell differentiation

NANOGP8 NANOG HNRNPU

5.06e-0533453GO:2000737
GeneOntologyBiologicalProcessnegative regulation of endodermal cell differentiation

NANOGP8 NANOG

6.94e-056452GO:1903225
GeneOntologyBiologicalProcessregulation of neurotransmitter secretion

CACNA1A CACNA1B CACNA1E UNC13A

1.27e-04118454GO:0046928
GeneOntologyBiologicalProcessnegative regulation of cell fate specification

NANOGP8 NANOG

1.29e-048452GO:0009996
GeneOntologyBiologicalProcesscalcium ion import across plasma membrane

CACNA1A CACNA1B CACNA1E

1.57e-0448453GO:0098703
GeneOntologyBiologicalProcesscalcium ion import into cytosol

CACNA1A CACNA1B CACNA1E

1.57e-0448453GO:1902656
GeneOntologyBiologicalProcesssynaptic vesicle exocytosis

CACNA1A CACNA1B CACNA1E UNC13A

1.58e-04125454GO:0016079
GeneOntologyBiologicalProcessstem cell division

NANOGP8 TIAL1 NANOG

1.67e-0449453GO:0017145
GeneOntologyBiologicalProcessresponse to pain

CACNA1A CACNA1B CACNA1E

1.88e-0451453GO:0048265
GeneOntologyBiologicalProcessnuclear-transcribed mRNA catabolic process

TNRC6B SMG1 HNRNPU TNRC6A

1.95e-04132454GO:0000956
GeneOntologyBiologicalProcessregulation of endodermal cell differentiation

NANOGP8 NANOG

2.07e-0410452GO:1903224
GeneOntologyBiologicalProcessregulation of neurotransmitter transport

CACNA1A CACNA1B CACNA1E UNC13A

2.51e-04141454GO:0051588
GeneOntologyBiologicalProcessendodermal cell fate specification

NANOGP8 NANOG

2.53e-0411452GO:0001714
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

CACNA1A KCNK5 CACNA1B CACNA1E

2.58e-04142454GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

CACNA1A KCNK5 CACNA1B CACNA1E

2.58e-04142454GO:0098659
GeneOntologyBiologicalProcesssynaptic vesicle cycle

CACNA1A CACNA1B CACNA1E SCRN1 UNC13A

2.66e-04264455GO:0099504
GeneOntologyBiologicalProcessexocytosis

FGA CACNA1A CACNA1B CACNA1E SCRN1 UNC13A

3.41e-04434456GO:0006887
GeneOntologyBiologicalProcessnuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

TNRC6B HNRNPU TNRC6A

3.86e-0465453GO:0000288
GeneOntologyBiologicalProcesspositive regulation of nuclear-transcribed mRNA poly(A) tail shortening

TNRC6B TNRC6A

4.17e-0414452GO:0060213
GeneOntologyBiologicalProcesscell dedifferentiation

NANOGP8 NANOG

4.80e-0415452GO:0043697
GeneOntologyBiologicalProcessdedifferentiation

NANOGP8 NANOG

4.80e-0415452GO:0043696
GeneOntologyBiologicalProcesspositive regulation of stem cell proliferation

TIAL1 NANOG HNRNPU

5.21e-0472453GO:2000648
GeneOntologyBiologicalProcessregulation of nuclear-transcribed mRNA poly(A) tail shortening

TNRC6B TNRC6A

5.48e-0416452GO:0060211
GeneOntologyBiologicalProcessnegative regulation of cell fate commitment

NANOGP8 NANOG

6.20e-0417452GO:0010454
GeneOntologyBiologicalProcessvesicle-mediated transport in synapse

CACNA1A CACNA1B CACNA1E SCRN1 UNC13A

6.49e-04321455GO:0099003
GeneOntologyBiologicalProcessendodermal cell fate commitment

NANOGP8 NANOG

6.96e-0418452GO:0001711
GeneOntologyBiologicalProcessregulation of stem cell division

NANOGP8 NANOG

6.96e-0418452GO:2000035
GeneOntologyBiologicalProcesscalcium ion transport

CACNA1A CACNA1B NIPSNAP2 CACNA1E SARAF RYR1

7.89e-04509456GO:0006816
GeneOntologyBiologicalProcesssignal release from synapse

CACNA1A CACNA1B CACNA1E UNC13A

8.52e-04195454GO:0099643
GeneOntologyBiologicalProcessneurotransmitter secretion

CACNA1A CACNA1B CACNA1E UNC13A

8.52e-04195454GO:0007269
GeneOntologyBiologicalProcessendoderm development

NANOGP8 NANOG TNRC6A

9.35e-0488453GO:0007492
GeneOntologyBiologicalProcessmesodermal cell fate commitment

NANOGP8 NANOG

1.14e-0323452GO:0001710
GeneOntologyCellularComponentcytoplasmic ribonucleoprotein granule

HELZ2 TNRC6B SMG1 TIA1 TIAL1 HNRNPU TNRC6A

1.88e-06269467GO:0036464
GeneOntologyCellularComponentribonucleoprotein granule

HELZ2 TNRC6B SMG1 TIA1 TIAL1 HNRNPU TNRC6A

2.89e-06287467GO:0035770
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA1A CACNA1B CACNA1E RYR1

3.13e-0646464GO:0005891
GeneOntologyCellularComponentcalcium channel complex

CACNA1A CACNA1B CACNA1E RYR1

2.00e-0573464GO:0034704
GeneOntologyCellularComponentcation channel complex

CACNA1A CACNA1B CACNA1E RYR1 SCN4A

1.62e-04235465GO:0034703
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA1A KCNK5 CACNA1B CACNA1E RYR1 SCN4A

1.71e-04378466GO:0034702
GeneOntologyCellularComponentcell surface

PKHD1 FGA ADGRF5 MFGE8 CEACAM5 CTSB ADAMTS7 MRC2 HNRNPU

6.08e-041111469GO:0009986
GeneOntologyCellularComponenttransmembrane transporter complex

CACNA1A KCNK5 CACNA1B CACNA1E RYR1 SCN4A

9.55e-04523466GO:1902495
GeneOntologyCellularComponenttransporter complex

CACNA1A KCNK5 CACNA1B CACNA1E RYR1 SCN4A

1.24e-03550466GO:1990351
MousePhenoabnormal respiration

PKHD1 CACNA1A KCNK5 MFAP4 ADGRF5 ADAMTS7 UNC13A RYR1 SCN4A

3.02e-05598399MP:0001943
MousePhenoabnormal muscle electrophysiology

CACNA1A RYR1 SCN4A

9.42e-0532393MP:0004145
MousePhenoabnormal channel response

CACNA1A CACNA1B CACNA1E

1.03e-0433393MP:0003484
MousePhenoincreased total lung capacity

MFAP4 ADAMTS7

1.58e-047392MP:0010937
DomainVDCC_a1su_IQ

CACNA1A CACNA1B CACNA1E

4.54e-077453IPR014873
DomainGPHH

CACNA1A CACNA1B CACNA1E

4.54e-077453PF16905
DomainGPHH_dom

CACNA1A CACNA1B CACNA1E

4.54e-077453IPR031649
DomainCa_chan_IQ

CACNA1A CACNA1B CACNA1E

4.54e-077453SM01062
DomainCa_chan_IQ

CACNA1A CACNA1B CACNA1E

4.54e-077453PF08763
DomainVDCCAlpha1

CACNA1A CACNA1B CACNA1E

1.55e-0610453IPR002077
DomainIon_trans_dom

CACNA1A CACNA1B CACNA1E RYR1 SCN4A

7.80e-06114455IPR005821
DomainIon_trans

CACNA1A CACNA1B CACNA1E RYR1 SCN4A

7.80e-06114455PF00520
DomainChannel_four-helix_dom

CACNA1A CACNA1B CACNA1E SCN4A

1.06e-0557454IPR027359
Domain-

CACNA1A CACNA1B CACNA1E SCN4A

1.06e-05574541.20.120.350
DomainAgo_hook

TNRC6B TNRC6A

1.70e-053452PF10427
DomainTNRC6_PABC-bd

TNRC6B TNRC6A

1.70e-053452IPR032226
DomainArgonaute_hook_dom

TNRC6B TNRC6A

1.70e-053452IPR019486
DomainTNRC6-PABC_bdg

TNRC6B TNRC6A

1.70e-053452PF16608
DomainNIPSNAP

NIPSNAP2 NIPSNAP1

3.40e-054452IPR012577
DomainNIPSNAP

NIPSNAP2 NIPSNAP1

3.40e-054452PF07978
DomainDimeric_a/b-barrel

NIPSNAP2 NIPSNAP1

1.18e-047452IPR011008
DomainRRM_dom_euk

TIA1 TIAL1

1.39e-0323452IPR003954
DomainRRM_1

TIA1 TIAL1

1.39e-0323452SM00361
DomainFibrinogen_a/b/g_C_2

FGA MFAP4

1.51e-0324452IPR014715
Domain-

FGA MFAP4

1.51e-03244524.10.530.10
DomainFibrinogen_C

FGA MFAP4

1.92e-0327452PF00147
DomainFBG

FGA MFAP4

2.21e-0329452SM00186
DomainRRM

TNRC6B TIA1 TIAL1 TNRC6A

2.25e-03230454PS50102
Domain-

FGA MFAP4

2.37e-03304523.90.215.10
DomainFibrinogen_a/b/g_C_1

FGA MFAP4

2.37e-0330452IPR014716
DomainFIBRINOGEN_C_1

FGA MFAP4

2.69e-0332452PS00514
DomainFibrinogen_a/b/g_C_dom

FGA MFAP4

2.69e-0332452IPR002181
DomainFIBRINOGEN_C_2

FGA MFAP4

2.69e-0332452PS51406
Domain-

TNRC6B TIA1 TIAL1 TNRC6A

2.78e-032444543.30.70.330
DomainGPS

ADGRF5 ADGRG4

3.03e-0334452SM00303
DomainGPCR_2_secretin-like_CS

ADGRF5 ADGRG4

3.03e-0334452IPR017983
DomainGPS

ADGRF5 ADGRG4

3.21e-0335452PF01825
DomainGPS

ADGRF5 ADGRG4

3.39e-0336452PS50221
DomainNucleotide-bd_a/b_plait

TNRC6B TIA1 TIAL1 TNRC6A

3.40e-03258454IPR012677
DomainGPS

ADGRF5 ADGRG4

3.58e-0337452IPR000203
DomainG_PROTEIN_RECEP_F2_1

ADGRF5 ADGRG4

4.18e-0340452PS00649
DomainGPCR_2_extracellular_dom

ADGRF5 ADGRG4

4.18e-0340452IPR001879
DomainG_PROTEIN_RECEP_F2_3

ADGRF5 ADGRG4

4.18e-0340452PS50227
DomainG_PROTEIN_RECEP_F2_2

ADGRF5 ADGRG4

6.46e-0350452PS00650
Domain7tm_2

ADGRF5 ADGRG4

6.46e-0350452PF00002
DomainHomeodomain-like

DMTF1 NANOGP8 HOXB13 NANOG

8.24e-03332454IPR009057
DomainGPCR_2_secretin-like

ADGRF5 ADGRG4

9.19e-0360452IPR000832
DomainGPCR_2-like

ADGRF5 ADGRG4

9.19e-0360452IPR017981
DomainG_PROTEIN_RECEP_F2_4

ADGRF5 ADGRG4

9.49e-0361452PS50261
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

CACNA1A CACNA1B CACNA1E RYR1

2.00e-0811414M47958
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1B CACNA1E

3.71e-0611413MM14498
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1B CACNA1E

3.71e-0611413M26913
PathwayKEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1A CACNA1B CACNA1E

3.88e-0523413M47666
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNA1A CACNA1B CACNA1E

5.02e-0525413M47948
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

TNRC6B TNRC6A

1.23e-046412MM15083
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

TNRC6B TNRC6A

1.72e-047412M46421
PathwayREACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION

TNRC6B TNRC6A

2.93e-049412M27810
PathwayREACTOME_REGULATION_OF_NPAS4_MRNA_TRANSLATION

TNRC6B TNRC6A

2.93e-049412M46436
PathwayKEGG_TYPE_II_DIABETES_MELLITUS

CACNA1A CACNA1B CACNA1E

3.39e-0447413M19708
PathwayREACTOME_REGULATION_OF_CDH11_MRNA_TRANSLATION_BY_MICRORNAS

TNRC6B TNRC6A

3.66e-0410412M48013
PathwayWP_SYNAPTIC_VESICLE_PATHWAY

CACNA1A CACNA1B UNC13A

4.32e-0451413M39457
PathwayREACTOME_REGULATION_OF_NPAS4_GENE_EXPRESSION

TNRC6B TNRC6A

6.31e-0413412M46434
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

CACNA1A CACNA1B CACNA1E RYR1

8.52e-04147414MM15854
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

CACNA1A CACNA1B CACNA1E RYR1

9.41e-04151414M39329
PathwayREACTOME_REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY

TNRC6B TNRC6A

1.09e-0317412M27788
PathwayWP_AFFECTED_PATHWAYS_IN_DUCHENNE_MUSCULAR_DYSTROPHY

FGA SARAF RYR1

1.28e-0374413M48080
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_APOPTOSIS

TNRC6B TNRC6A

1.37e-0319412M48238
PathwayWP_GPCRS_ORPHAN

ADGRF5 ADGRG4

1.37e-0319412MM15991
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1A CACNA1B CACNA1E RYR1

1.73e-03178414M2890
Pubmed

The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels.

CACNA1A CACNA1B CACNA1E

2.17e-09346338996073
Pubmed

Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics.

CACNA1A CACNA1B CACNA1E

2.17e-09346324523520
Pubmed

Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry.

CACNA1A CACNA1B CACNA1E

8.65e-09446332616470
Pubmed

Cerebellar granule cell signaling is indispensable for normal motor performance.

CACNA1A CACNA1B CACNA1E

8.65e-09446337141091
Pubmed

Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits.

CACNA1A CACNA1B CACNA1E

2.16e-0854638825650
Pubmed

Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.

CACNA1A CACNA1B CACNA1E

2.16e-08546315451373
Pubmed

The proximal region of the 3'-untranslated region of cyclooxygenase-2 is recognized by a multimeric protein complex containing HuR, TIA-1, TIAR, and the heterogeneous nuclear ribonucleoprotein U.

TIA1 TIAL1 HNRNPU

2.16e-08546312855701
Pubmed

Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.

CACNA1A CACNA1B CACNA1E

2.16e-08546311296258
Pubmed

An action potential initiation mechanism in distal axons for the control of dopamine release.

CACNA1A CACNA1B CACNA1E

4.32e-08646335324301
Pubmed

Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.

CACNA1A CACNA1B CACNA1E

4.32e-08646312827191
Pubmed

Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors.

CACNA1A CACNA1B CACNA1E

4.32e-0864639238069
Pubmed

Rebuilding essential active zone functions within a synapse.

CACNA1A CACNA1B CACNA1E

7.55e-08746335176221
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1A CACNA1B CACNA1E

1.81e-07946316382099
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1A CACNA1B CACNA1E RYR1

1.91e-073846430786075
Pubmed

Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.

CACNA1A CACNA1B CACNA1E

9.74e-071546320188150
Pubmed

Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.

CACNA1A CACNA1B CACNA1E

9.74e-071546324453333
Pubmed

RBM19 is essential for preimplantation development in the mouse.

NANOGP8 NANOG TNRC6A

9.74e-071546319087264
Pubmed

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.

NANOGP8 TIA1 FUBP3 NANOG HNRNPU

9.87e-0713546531077711
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNA1A KCNK5 CACNA1B CACNA1E SCN4A

1.14e-0613946516985003
Pubmed

The REV7 subunit of DNA polymerase ζ is essential for primordial germ cell maintenance in the mouse.

NANOGP8 TIAL1 NANOG

1.20e-061646323463509
Pubmed

iCLIP predicts the dual splicing effects of TIA-RNA interactions.

TIA1 TIAL1

1.71e-06246221048981
Pubmed

Identification of chosen apoptotic (TIAR and TIA-1) markers expression in thyroid tissues from adolescents with immune and non-immune thyroid diseases.

TIA1 TIAL1

1.71e-06246220675271
Pubmed

TIA-1 and TIAR activate splicing of alternative exons with weak 5' splice sites followed by a U-rich stretch on their own pre-mRNAs.

TIA1 TIAL1

1.71e-06246211514562
Pubmed

Role of GW182 protein in the cell.

TNRC6B TNRC6A

1.71e-06246229791863
Pubmed

Blocking the R-type (Cav2.3) Ca2+ channel enhanced morphine analgesia and reduced morphine tolerance.

CACNA1B CACNA1E

1.71e-06246215610184
Pubmed

Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels.

CACNA1A CACNA1B

1.71e-06246223426690
Pubmed

Two isoforms of the T-cell intracellular antigen 1 (TIA-1) splicing factor display distinct splicing regulation activities. Control of TIA-1 isoform ratio by TIA-1-related protein.

TIA1 TIAL1

1.71e-06246217488725
Pubmed

Compensatory contribution of Cav2.3 channels to acetylcholine release at the neuromuscular junction of tottering mice.

CACNA1A CACNA1E

1.71e-06246216381801
Pubmed

Development of Purkinje cell degeneration in a knockin mouse model reveals lysosomal involvement in the pathogenesis of SCA6.

CACNA1A CTSB

1.71e-06246223054835
Pubmed

The stress granule component TIA-1 binds tick-borne encephalitis virus RNA and is recruited to perinuclear sites of viral replication to inhibit viral translation.

TIA1 TIAL1

1.71e-06246224696465
Pubmed

T-cell intracellular antigen (TIA)-proteins deficiency in murine embryonic fibroblasts alters cell cycle progression and induces autophagy.

TIA1 TIAL1

1.71e-06246224086455
Pubmed

NIPSNAP1 and NIPSNAP2 Act as "Eat Me" Signals for Mitophagy.

NIPSNAP2 NIPSNAP1

1.71e-06246230982665
Pubmed

Mitochondrial proteins NIP-SNAP-1 and -2 are a target for the immunomodulatory activity of clarithromycin, which involves NF-κB-mediated cytokine production.

NIPSNAP2 NIPSNAP1

1.71e-06246227998764
Pubmed

Functional evidence that the self-renewal gene NANOG regulates human tumor development.

NANOGP8 NANOG

1.71e-06246219415763
Pubmed

Synthetic Aβ oligomers (Aβ(1-42) globulomer) modulate presynaptic calcium currents: prevention of Aβ-induced synaptic deficits by calcium channel blockers.

CACNA1A CACNA1B

1.71e-06246223376566
Pubmed

Genome-wide profiling reveals a role for T-cell intracellular antigens TIA1 and TIAR in the control of translational specificity in HeLa cells.

TIA1 TIAL1

1.71e-06246224927121
Pubmed

Splicing of the large intron present in the nonstructural gene of minute virus of mice is governed by TIA-1/TIAR binding downstream of the nonconsensus donor.

TIA1 TIAL1

1.71e-06246219339348
Pubmed

Structure, tissue distribution and genomic organization of the murine RRM-type RNA binding proteins TIA-1 and TIAR.

TIA1 TIAL1

1.71e-0624628871565
Pubmed

Nanog1 in NTERA-2 and recombinant NanogP8 from somatic cancer cells adopt multiple protein conformations and migrate at multiple M.W species.

NANOGP8 NANOG

1.71e-06246224598770
Pubmed

Identification of the sequence determinants mediating the nucleo-cytoplasmic shuttling of TIAR and TIA-1 RNA-binding proteins.

TIA1 TIAL1

1.71e-06246216278295
Pubmed

Differential expression of nanog1 and nanogp8 in colon cancer cells.

NANOGP8 NANOG

1.71e-06246222079639
Pubmed

Individual RNA recognition motifs of TIA-1 and TIAR have different RNA binding specificities.

TIA1 TIAL1

1.71e-0624628576255
Pubmed

CaV 2.1 α1  subunit motifs that control presynaptic CaV 2.1 subtype abundance are distinct from CaV 2.1 preference.

CACNA1A CACNA1B

1.71e-06246238155373
Pubmed

TIAR and TIA-1 mRNA-binding proteins co-aggregate under conditions of rapid oxygen decline and extreme hypoxia and suppress the HIF-1α pathway.

TIA1 TIAL1

1.71e-06246220980400
Pubmed

Effects of ablation of N- and R-type Ca(2+) channels on pain transmission.

CACNA1B CACNA1E

1.71e-06246212074836
Pubmed

A systematic analysis of intronic sequences downstream of 5' splice sites reveals a widespread role for U-rich motifs and TIA1/TIAL1 proteins in alternative splicing regulation.

TIA1 TIAL1

1.71e-06246218456862
Pubmed

Expression analysis of P/Q-type Ca2+ channel alpha 1A subunit mRNA in olfactory mitral cell in N-type Ca2+ channel alpha 1B subunit gene-deficient mice.

CACNA1A CACNA1B

1.71e-06246215050706
Pubmed

Structure of the central RNA recognition motif of human TIA-1 at 1.95A resolution.

TIA1 TIAL1

1.71e-06246218201561
Pubmed

TIA-1 and TIAR interact with 5'-UTR of enterovirus 71 genome and facilitate viral replication.

TIA1 TIAL1

1.71e-06246226363455
Pubmed

TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha.

TIA1 TIAL1

1.71e-06246210921895
Pubmed

Expression of NANOG and NANOGP8 in a variety of undifferentiated and differentiated human cells.

NANOGP8 NANOG

1.71e-06246221136380
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

NIPSNAP2 SMG1 MFAP4 HERC2 ADGRG4 HNRNPU NIPSNAP1 TNRC6A

1.75e-0663946823443559
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

CACNA1A CACNA1B NIPSNAP2 TNRC6B SCRN1 LRP1B UNC13A HNRNPU NIPSNAP1 TNRC6A

1.90e-061139461036417873
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

NANOGP8 LRP1B NANOG

2.83e-062146321337463
Pubmed

A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome.

NANOGP8 NANOG HNRNPU

3.28e-062246319483677
Pubmed

TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.

TNRC6B TIA1 TIAL1 FUBP3 HNRNPU TNRC6A

3.77e-0631746630997501
Pubmed

NIP-SNAP-1 and -2 mitochondrial proteins are maintained by heat shock protein 60.

NIPSNAP2 NIPSNAP1

5.13e-06346228011268
Pubmed

Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.

NANOGP8 NANOG

5.13e-06346219447925
Pubmed

The pluripotency factor NANOG controls primitive hematopoiesis and directly regulates Tal1.

NANOGP8 NANOG

5.13e-06346230814124
Pubmed

The molecular logic of Nanog-induced self-renewal in mouse embryonic stem cells.

NANOGP8 NANOG

5.13e-06346230846691
Pubmed

Generation of germline-competent induced pluripotent stem cells.

NANOGP8 NANOG

5.13e-06346217554338
Pubmed

Multiple phases in regulation of Nanog expression during pre-implantation development.

NANOGP8 NANOG

5.13e-06346226660234
Pubmed

Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog.

NANOGP8 NANOG

5.13e-06346218177668
Pubmed

Expression of Nanog gene promotes NIH3T3 cell proliferation.

NANOGP8 NANOG

5.13e-06346216259959
Pubmed

Differential alterations in expressions of ryanodine receptor subtypes in cerebellar cortical neurons of an ataxic mutant, rolling mouse Nagoya.

CACNA1A RYR1

5.13e-06346218313230
Pubmed

A novel NK-type homeobox gene, ENK (early embryo specific NK), preferentially expressed in embryonic stem cells.

NANOGP8 NANOG

5.13e-06346212609610
Pubmed

Cutting edge: Hypoxia-induced Nanog favors the intratumoral infiltration of regulatory T cells and macrophages via direct regulation of TGF-β1.

NANOGP8 NANOG

5.13e-06346224227785
Pubmed

Nanog co-regulated by Nodal/Smad2 and Oct4 is required for pluripotency in developing mouse epiblast.

NANOGP8 NANOG

5.13e-06346224929238
Pubmed

Munc13-3 Is Required for the Developmental Localization of Ca2+ Channels to Active Zones and the Nanopositioning of Cav2.1 Near Release Sensors.

CACNA1A CACNA1B

5.13e-06346229466725
Pubmed

Nanog and transcriptional networks in embryonic stem cell pluripotency.

NANOGP8 NANOG

5.13e-06346217211451
Pubmed

The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis.

NANOGP8 NANOG

5.13e-06346223770853
Pubmed

The stem cell pluripotency factor NANOG activates transcription with two unusually potent subdomains at its C terminus.

NANOGP8 NANOG

5.13e-06346215502159
Pubmed

Nanog variability and pluripotency regulation of embryonic stem cells--insights from a mathematical model analysis.

NANOGP8 NANOG

5.13e-06346220574542
Pubmed

lincRNAs act in the circuitry controlling pluripotency and differentiation.

NANOGP8 NANOG

5.13e-06346221874018
Pubmed

Cell signalling regulates dynamics of Nanog distribution in embryonic stem cell populations.

NANOGP8 NANOG

5.13e-06346223054952
Pubmed

Nanog-independent reprogramming to iPSCs with canonical factors.

NANOGP8 NANOG

5.13e-06346224527385
Pubmed

Aromatic residues in the C-terminal domain 2 are required for Nanog to mediate LIF-independent self-renewal of mouse embryonic stem cells.

NANOGP8 NANOG

5.13e-06346218086680
Pubmed

TIA nuclear proteins regulate the alternate splicing of lysyl hydroxylase 2.

TIA1 TIAL1

5.13e-06346219110540
Pubmed

TIA1 prevents skipping of a critical exon associated with spinal muscular atrophy.

TIA1 TIAL1

5.13e-06346221189287
Pubmed

Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells.

NANOGP8 NANOG

5.13e-06346217204467
Pubmed

CrxOS maintains the self-renewal capacity of murine embryonic stem cells.

NANOGP8 NANOG

5.13e-06346219800316
Pubmed

Chromatin decondensation and nuclear softening accompany Nanog downregulation in embryonic stem cells.

NANOGP8 NANOG

5.13e-06346223200040
Pubmed

Selenium Augments microRNA Directed Reprogramming of Fibroblasts to Cardiomyocytes via Nanog.

NANOGP8 NANOG

5.13e-06346226975336
Pubmed

Nanog suppresses cell migration by downregulating thymosin β4 and Rnd3.

NANOGP8 NANOG

5.13e-06346223329853
Pubmed

Ankyrin-B regulates Cav2.1 and Cav2.2 channel expression and targeting.

CACNA1A CACNA1B

5.13e-06346224394417
Pubmed

NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers.

NANOGP8 NANOG

5.13e-06346226751055
Pubmed

Epigenetic regulation of Nanog gene in embryonic stem and trophoblast stem cells.

NANOGP8 NANOG

5.13e-06346217352742
Pubmed

OCT4/SOX2-independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells.

NANOGP8 NANOG

5.13e-06346223178592
Pubmed

Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency.

NANOGP8 NANOG

5.13e-06346225005472
Pubmed

Roles of the Nanog protein in murine F9 embryonal carcinoma cells and their endoderm-differentiated counterparts.

NANOGP8 NANOG

5.13e-06346216773043
Pubmed

Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming.

NANOGP8 NANOG

5.13e-06346223665121
Pubmed

Ectopic overexpression of Nanog induces tumorigenesis in non-tumorous fibroblasts.

NANOGP8 NANOG

5.13e-06346226733157
Pubmed

mNanog possesses dorsal mesoderm-inducing ability by modulating both BMP and Activin/nodal signaling in Xenopus ectodermal cells.

NANOGP8 NANOG

5.13e-06346223071603
Pubmed

Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features.

NANOGP8 NANOG

5.13e-06346216501172
Pubmed

Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells.

NANOGP8 NANOG

5.13e-06346219582141
Pubmed

NANOG induction of fetal liver kinase-1 (FLK1) transcription regulates endothelial cell proliferation and angiogenesis.

NANOGP8 NANOG

5.13e-06346221119109
Pubmed

Pluripotency factor NANOG promotes germ cell maintenance in vitro without triggering dedifferentiation of spermatogonial stem cells.

NANOGP8 NANOG

5.13e-06346232145514
Pubmed

Nanog is the gateway to the pluripotent ground state.

NANOGP8 NANOG

5.13e-06346219703398
Pubmed

Nanog safeguards pluripotency and mediates germline development.

NANOGP8 NANOG

5.13e-06346218097409
Pubmed

Nanog Fluctuations in Embryonic Stem Cells Highlight the Problem of Measurement in Cell Biology.

NANOGP8 NANOG

5.13e-06346228636920
InteractionMOV10 interactions

NIPSNAP2 TNRC6B SMG1 DFFA SARAF TIAL1 CANT1 FUBP3 UNC13A NANOG HNRNPU NIPSNAP1 B4GALT4 TNRC6A

3.60e-0712974414int:MOV10
InteractionTOP3B interactions

HELZ2 KCNK5 TNRC6B ARSJ HERC2 TIA1 ADAMTS7 CANT1 FUBP3 PCNX4 HOXB13 RYR1 HNRNPU NIPSNAP1

1.63e-0614704414int:TOP3B
InteractionPABPC1 interactions

TNRC6B SMG1 USP4 HERC2 TIA1 TIAL1 FUBP3 NANOG HNRNPU TNRC6A

2.02e-066994410int:PABPC1
InteractionFAM120C interactions

TNRC6B SMG1 TIAL1 FUBP3 HNRNPU TNRC6A

3.51e-06191446int:FAM120C
InteractionHRG interactions

FGA SARAF LRP1B NANOG

1.07e-0563444int:HRG
InteractionYTHDF3 interactions

TNRC6B SMG1 TIAL1 CTSB FUBP3 TNRC6A

1.49e-05246446int:YTHDF3
InteractionDAZL interactions

TNRC6B SMG1 TIAL1 FUBP3 TNRC6A

1.56e-05145445int:DAZL
InteractionRB1CC1 interactions

TNRC6B MFGE8 HERC2 MRC2 NANOG HNRNPU TNRC6A

1.89e-05387447int:RB1CC1
InteractionCACNB4 interactions

CACNA1A CACNA1B TIA1

2.16e-0525443int:CACNB4
InteractionTIA1 interactions

NIPSNAP2 TIA1 TIAL1 FUBP3 NANOG NIPSNAP1

2.79e-05275446int:TIA1
InteractionSMG5 interactions

TNRC6B SMG1 FUBP3 TNRC6A

3.36e-0584444int:SMG5
InteractionTIAL1 interactions

TIA1 TIAL1 FUBP3 NANOG HNRNPU

3.54e-05172445int:TIAL1
InteractionDDX1 interactions

FGA HERC2 TIA1 TIAL1 FUBP3 NANOG HNRNPU

5.93e-05463447int:DDX1
InteractionNDP interactions

ADAMTS7 LRP1B MRC2

6.05e-0535443int:NDP
InteractionTMPRSS13 interactions

MFGE8 MAN1A1 CANT1 B4GALT4

8.35e-05106444int:TMPRSS13
InteractionDEFB136 interactions

ADAMTS7 LRP1B MRC2

1.21e-0444443int:DEFB136
InteractionFMR1 interactions

TNRC6B SMG1 HERC2 TIA1 TIAL1 FUBP3 HNRNPU

1.48e-04536447int:FMR1
InteractionOTUD4 interactions

TNRC6B TIA1 TIAL1 FUBP3 TNRC6A

1.58e-04236445int:OTUD4
InteractionSOX2 interactions

HELZ2 FGA MFAP4 MFGE8 TIA1 TIAL1 FUBP3 NANOG RYR1 HNRNPU TNRC6A

1.82e-0414224411int:SOX2
InteractionPRRC2A interactions

FGA TNRC6B SMG1 TIAL1 FUBP3 TNRC6A

1.89e-04389446int:PRRC2A
InteractionUNK interactions

TNRC6B SMG1 CTSB FUBP3 HNRNPU TNRC6A

2.44e-04408446int:UNK
InteractionLSM14A interactions

TNRC6B SMG1 TIA1 FUBP3 HNRNPU

2.48e-04260445int:LSM14A
GeneFamilyCalcium voltage-gated channel subunits

CACNA1A CACNA1B CACNA1E

1.16e-0526313253
GeneFamilyFibrinogen C domain containing

FGA MFAP4

8.33e-0425312554
GeneFamilyAtaxins|Trinucleotide repeat containing

TNRC6B TNRC6A

8.33e-0425312775
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

ADGRF5 CEACAM5 KIRREL2

2.59e-03161313593
GeneFamilyImmunoglobulin like domain containing

ADGRF5 CEACAM5 KIRREL2

4.32e-03193313594
GeneFamilyNKL subclass homeoboxes and pseudogenes

NANOGP8 NANOG

5.87e-0367312519
CoexpressionGSE14308_TH1_VS_INDUCED_TREG_UP

KCNK5 CACNA1B TNRC6B SMG1 SARAF TIA1

1.16e-06200456M3378
CoexpressionLAKE_ADULT_KIDNEY_C14_DISTAL_CONVOLUTED_TUBULE

PKHD1 TNRC6B MAN1A1 LRP1B TNRC6A

2.83e-05208455M39233
CoexpressionWILSON_PROTEASES_AT_TUMOR_BONE_INTERFACE_DN

CTSB ADAMTS7

2.87e-055452M1794
CoexpressionAtlasAravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_1000_k-means-cluster#5

KCNK5 NANOGP8 KIRREL2 UNC13A NANOG RYR1 SCN4A

8.56e-05505457Arv_SC-H9hpx_1000_K5
CoexpressionAtlasAravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000_k-means-cluster#3

KCNK5 NANOGP8 KIRREL2 UNC13A NANOG RYR1 SCN4A

9.11e-05510457Arv_SC-hpx_blastocyst_1000_K3
CoexpressionAtlasAravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500_k-means-cluster#5

KCNK5 NANOGP8 UNC13A NANOG SCN4A

1.28e-04232455Arv_SC-hpx_blastocyst_500_K5
CoexpressionAtlasAravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_500_k-means-cluster#1

KCNK5 NANOGP8 UNC13A NANOG SCN4A

1.28e-04232455Arv_SC-H9hpx_500_K1
CoexpressionAtlasratio_StemCell_vs_induced-Mesoderm_top-relative-expression-ranked_1000_k-means-cluster#5

CACNA1A NANOGP8 KIRREL2 UNC13A NANOG RYR1 SCN4A

1.30e-04540457ratio_SC_vs_MESO_1000_K5
CoexpressionAtlasAravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000_k-means-cluster#2

KCNK5 NANOGP8 KIRREL2 UNC13A NANOG RYR1 SCN4A

1.52e-04554457Arv_SC_fibroblast_1000_K2
CoexpressionAtlasAravindRamakr_StemCell-HD_top-relative-expression-ranked_1000_k-means-cluster#1

KCNK5 NANOGP8 KIRREL2 UNC13A NANOG RYR1 SCN4A

1.57e-04557457Arv_SC-HD_1000_K1
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_500

CACNA1B TNRC6B SMG1 SCRN1 MFAP4 HOXB13

2.33e-04416456gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000

CACNA1B SMG1 MFAP4 TIAL1 CTSB ADAMTS7 MRC2 HOXB13

2.58e-04806458gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlasratio_StemCell_vs_EmbryoidBody_top-relative-expression-ranked_1000_k-means-cluster#2

KCNK5 MFGE8 NANOGP8 UNC13A NANOG RYR1 SCN4A

2.82e-04613457ratio_SC_vs_EB_1000_K2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000

CACNA1B TNRC6B SMG1 SCRN1 MFAP4 HERC2 CTSB HOXB13

2.85e-04818458gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1A CACNA1B LRP1B UNC13A RYR1

4.23e-071504550205318a870e091add66ee4305747dda9f51510d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1A CACNA1B CACNA1E UNC13A RYR1

7.19e-071674553edb0570e583bb527165bcd8a4c25a042054043b
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A CACNA1B CEACAM5 UNC13A HOXB13

7.85e-071704556a98f47f8c2b5b15e09169bd82eff1e6bf76e5a6
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A ARSJ KIRREL2 UNC13A HOXB13

1.01e-06179455d70791d2a0db35a6b013fa7ed2f9f39364581eff
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A MAN1A1 ARSJ LRP1B ADGRG4

1.19e-06185455eb78614c4acf8d2ce7874d7e51e16997b76127ef
ToppCellEpithelial-Epithelial-B_(AT1-AT2-progenitors)|Epithelial / shred on cell class and cell subclass (v4)

DMTF1 ADGRF5 KIRREL2 MRC2

1.76e-05154454770712806e26f73456fb77a81aa4ef8ec78a21ea
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PKHD1 MAN1A1 CTSB SCN4A

2.37e-05166454bb8135119dc37fdbba476599a56d368f422688dc
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1A CACNA1B CACNA1E UNC13A

2.42e-05167454c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1B ARSJ UNC13A HOXB13

2.48e-051684544e1b522c7400c9d87f63c00e4e1dd07136095cd6
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A ARSJ UNC13A HOXB13

2.48e-0516845438ba7737ae0afffcbd3aa499403e83c24a922127
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1A CACNA1B CACNA1E UNC13A

2.54e-05169454b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK5 CACNA1E MAN1A1 HOXB13

2.84e-0517445428ec25767bbd4fd898738f9f4d2b585dc91b5adf
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A MAN1A1 ADGRG4 UNC13A

3.04e-0517745443dce527392f3b8364bb6a55268ce9d6518d3a29
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNK5 CACNA1E MAN1A1 HOXB13

3.25e-05180454d8135f73a89b97168f2048258f4648e23536ece4
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-Zbtb32+_B_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNK5 CACNA1E MAN1A1 HOXB13

3.25e-05180454c12c1cc206f7e63e5722471bd3eb84caddb84129
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A LRP1B ADGRG4 UNC13A

3.25e-051804546b1606238417490e0d9930870a7827419d1c3737
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MFAP4 MFGE8 MRC2 ADGRG4

4.44e-05195454f54bc4454270ff06e85596f98199372b50d0179f
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MFAP4 ADGRF5 MFGE8 MRC2

4.71e-05198454eb78b2ae6a787dbc75947e8dd5a03693285bc8be
ToppCellControl-Neutrophil|Control / Disease condition and Cell class

PKHD1 CACNA1E SARAF

2.79e-04126453450c01d89714feee6529680ec3ce69067a54b37c
ToppCellControl-Neutrophil-|Control / Disease condition and Cell class

PKHD1 CACNA1E SARAF

2.79e-0412645365fff5ec2296272e94f44546606587833191dd82
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1A CACNA1B LRP1B

2.92e-0412845391072ca56bce2c552a95edd67e17f43d8cc1de95
ToppCellCOVID-19-kidney-Epithelial_Doublet|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 CACNA1A LRP1B

3.06e-041304531ff28e9d3dc9a791e07d815f8fbb48f75d3f275b
ToppCellPND07-28-samps-Lymphocyte-B_cell-B_cell_2|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CACNA1E MAN1A1 SCN4A

3.57e-041374532544d1256f11da6e3bad24a871b2253e0ab20d01
ToppCellPND07-28-samps-Lymphocyte-B_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CACNA1E MAN1A1 SCN4A

3.57e-04137453874e2eaa7846a2832f46b77c726d79f220a4a1cd
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1A ADGRG4 RYR1

3.72e-0413945364c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CEACAM5 ARSJ KIRREL2

4.05e-04143453d0ed8c25da1327085e042c2e03cb7503e2c52ce0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CEACAM5 ARSJ KIRREL2

4.05e-041434538900b92a24289204b9ec7baccc11594fec7694f1
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 CACNA1B LRP1B

4.21e-0414545396712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FGA KCNK5 UNC13A

4.30e-04146453bb7bf20245d93c8812920dd0debbf1ed00add378
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1A CACNA1B LRP1B

4.47e-04148453d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PKHD1 KCNK5 MRC2

4.93e-04153453151c469b26f9adf04dd6f117f03bef760cc3d45d
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MFAP4 ADAMTS7 MRC2

5.02e-0415445365dbb60f636562eeba3dafadae9c0c7db2b27476
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKHD1 KCNK5 CACNA1B

5.31e-041574534766f7d545bf2d775390589460677519cb92f4d5
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MFAP4 MRC2 SCN4A

5.51e-04159453cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1A CACNA1B RYR1

5.51e-041594535335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 CACNA1B LRP1B

5.61e-04160453c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 CACNA1B LRP1B

5.61e-0416045325c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRF5 MAN1A1 LRP1B

5.82e-041624538e0f03fcc25b2ea777e8478fbf771699cf93719c
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A UNC13A HOXB13

5.82e-04162453f2a87019ff9b466617e90c60d182ab7d14581cc9
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PKHD1 CACNA1B LRP1B

5.82e-04162453bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRF5 MAN1A1 LRP1B

5.82e-04162453e0417f1242edf71934fe62bccc55c4678f7ff4ac
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1A UNC13A RYR1

5.92e-0416345319c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellnormal_Lung-Epithelial_cells-Undetermined|normal_Lung / Location, Cell class and cell subclass

ADGRF5 CEACAM5 CTSB

6.03e-04164453fa2dae15b38cb8f9642dbf00549beec8ee19e9bb
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1A CACNA1B UNC13A

6.03e-04164453be49af6335f2505065cde2cb9800e4a5516811b1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MFAP4 MFGE8 MRC2

6.03e-0416445301a7c335897128d3478b8b9b44fb461cab493084
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A UNC13A HOXB13

6.14e-041654534b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E RYR1 SCN4A

6.14e-0416545336415924d05373e9dd3665be599f4f3f40bf0497
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E RYR1 SCN4A

6.14e-0416545356310fddd3d8e4afdfde066d26cee9747e5b8c6a
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A CEACAM5 UNC13A

6.25e-04166453d96c562e1483adb4cdd817b68133f03356d7279b
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1E MAN1A1 HOXB13

6.36e-041674538ec7a98b542b134f48df8fbec351693cc5cfe55c
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-plasma_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1E MAN1A1 HOXB13

6.36e-04167453a9f28c4649ce344ae3ba3a3acb58da9c7efad901
ToppCellfacs-Kidney-nan-24m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E RYR1 SCN4A

6.36e-041674533c4183a8225bae37b9f5341ebd1b95409ced2022
ToppCellfacs-Kidney-nan-24m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E RYR1 SCN4A

6.36e-0416745328e9670586ff551b700c794313d27eedbfa1286b
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like|GI_small-bowel / Manually curated celltypes from each tissue

FGA SCRN1 MFGE8

6.47e-04168453d02eba7ece17edcdd47fd6b784c93910ce61090f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PKHD1 KIRREL2 RYR1

6.58e-04169453a0681317867e31319210a23e56660a53f4529efe
ToppCellfacs-Heart-RA-24m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E RYR1 SCN4A

6.58e-04169453dcf92121fb00e3b6498e2648363e90ac044ea396
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PKHD1 CACNA1A CEACAM5

6.69e-04170453985c2d5962100fab0d95bee39f382ccbe799331e
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRF5 MFGE8 SCN4A

6.81e-04171453285533ca2a6a411773313166bee35542f34d1a3c
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E FUBP3 PCNX4

6.81e-04171453d1e87478d8c0329e662849823f5c7604f20e1b1a
ToppCellCOVID-19-Heart-T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1A UNC13A RYR1

6.81e-04171453b2e753e811a7639956994609f73efcdb62d04f82
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PKHD1 SCRN1 RYR1

6.92e-04172453ac20766d1fd43eab8c3ff5e7418a6b38bebf0bd5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PKHD1 SCRN1 RYR1

6.92e-041724533fd1bc4a8ced0bf9e26ca4ce6d83b5b97bbc2556
ToppCellE15.5-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CACNA1E SCRN1 LRP1B

6.92e-04172453a8b33d8ebc56e442a2ad6ac7dafd0c887571bd95
ToppCellfacs-Marrow-T-cells-24m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E CTSB RYR1

7.04e-04173453ca3d2a9562734f76127e3e7d54c10b63e95141bb
ToppCellfacs-Marrow-T-cells-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E CTSB RYR1

7.04e-0417345319a9e10885173d7712996be8660a3a5a7a9aa39f
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A CACNA1E ADGRG4

7.16e-041744533503c7dec498597f76a86dbd5e4bb2311e743bde
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E MFAP4 HOXB13

7.28e-0417545359249c9e83952d7277010e7be3c779e26399eb5d
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

CACNA1A CACNA1B UNC13A

7.28e-041754534db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CEACAM5 ARSJ HOXB13

7.28e-04175453019ea30ac55748463d7917abf3d3f0e804189bfd
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

CACNA1A CACNA1B UNC13A

7.28e-041754538d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E MFAP4 HOXB13

7.28e-04175453b35cc1357495f2a03a6500f807c6e6f8c877734d
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E MAN1A1 SCN4A

7.40e-04176453741fdacb33d49b030a797a6099fdea0949a22e75
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRF5 ARSJ PCNX4

7.40e-0417645325ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MFAP4 MRC2 B4GALT4

7.40e-04176453cb8fd56a4f935cdda19d7ab43382cdda7c307667
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5|TCGA-Skin / Sample_Type by Project: Shred V9

KCNK5 LRP1B MRC2

7.65e-04178453ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 KCNK5 CACNA1E

7.65e-0417845323a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CEACAM5 ARSJ HOXB13

7.65e-041784539099b47e0756d6a1b7ba1c6aa7b47c5425f649e0
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes-Myofibroblast|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MFAP4 MRC2 SCN4A

7.65e-041784531802ff1c6cb18ee62cfef7270c0971048fae5315
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes-Myofibroblast-VLMC_L1-3_CYP1B1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MFAP4 MRC2 SCN4A

7.65e-041784534368d20130e5a08716564c19470b6014f16902ac
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KCNK5 MFAP4 MRC2

7.65e-04178453cda7695411655bd6d0ba69e5041ca7530a9dad3a
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A SCRN1 ADGRF5

7.65e-0417845330ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KCNK5 RYR1 TNRC6A

7.77e-041794539dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A ARSJ ADGRG4

7.77e-041794538ce5000088b727783a0619baa16a2cd036d21f54
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A ARSJ ADGRG4

7.77e-04179453f2e8fc975c30992611630197b79daaeef7c4211d
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A ARSJ ADGRG4

7.77e-04179453ec7c38464863ac3744a8d4880f49421914892339
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MFAP4 MFGE8 MRC2

7.90e-04180453ea7a1ccf0dd3bb5af5df87501f873e7339a824b3
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MFAP4 MFGE8 MRC2

7.90e-04180453c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 KCNK5 CACNA1E

7.90e-04180453864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellMatrixFB-Fibroblast-A|MatrixFB / shred on cell class and cell subclass (v4)

MFAP4 MRC2 B4GALT4

7.90e-04180453adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MFAP4 MFGE8 MRC2

7.90e-0418045332c6a3886428d82fb4355d987c6d2645f333447b
ToppCellfacs-Spleen-nan-3m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 MFAP4 HNRNPU

7.90e-0418045387fb1fdbc49c808bb5f6fe9fb747057b45fa78d0
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARSJ UNC13A HOXB13

8.02e-041814532392af8c7f040c23a7d416c2e37419954970c8f4
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCRN1 CEACAM5 ADGRG4

8.02e-041814531d3d1b5a6efe9cedd03b7e0b5684df97f0246729
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

MFAP4 MFGE8 MRC2

8.02e-04181453bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCellfacs-SCAT-Fat-24m-Lymphocytic-B_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E HOXB13 SCN4A

8.02e-0418145314faef1dde781d501834379f2a6413e8d6a80b72
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCRN1 CEACAM5 ADGRG4

8.02e-041814530069e8308de932df43660bbe926637c57b8bf7f6
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 KCNK5 CACNA1E

8.02e-041814536980ea624151da32b7f537f263e40fcb87a02e81
ToppCellEpithelial-lung_neuroendocrine_cell_(PNEC)|World / Lineage, Cell type, age group and donor

CACNA1A CACNA1B UNC13A

8.15e-0418245357bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A UNC13A HOXB13

8.15e-041824530e589bf97d51b4b2f723f8c45853ad81b7ce8778
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MFAP4 MFGE8 MRC2

8.15e-04182453af65f0fc3f9e5d9ce69ee5faaf5b6cb7f8412e0c
DrugAC 110

CACNA1A CACNA1B CACNA1E

2.88e-084453CID000022860
Drug3,4-dihydroquinazoline

CACNA1A CACNA1B CACNA1E

1.44e-076453CID000583065
Drugalpha-sialylcholesterol

CACNA1A CACNA1B CACNA1E

1.44e-076453CID000133976
DrugAPMPA

CACNA1A CACNA1B CACNA1E

2.51e-077453CID000512300
DrugCNS 1145

CACNA1A CACNA1B CACNA1E RYR1

5.22e-0733454CID000190902
DrugIHC-64

CACNA1A CACNA1B CACNA1E RYR1

5.22e-0733454CID000162753
Drugriluzole

CACNA1A KCNK5 CACNA1B CACNA1E RYR1 SCN4A

1.16e-06174456CID000005070
Drugleys

CACNA1A CACNA1B CACNA1E

1.18e-0611453CID000484683
Drugmanidipine

FGA CACNA1A CACNA1B CACNA1E RYR1

1.22e-0695455CID000004008
DrugAC1L2VU3

CACNA1A CACNA1B CACNA1E

1.57e-0612453CID000129572
Drugisradipine

CACNA1A CACNA1B CACNA1E RYR1 SCN4A

1.57e-06100455CID000003784
Druggadolinium

CACNA1A KCNK5 CACNA1B CACNA1E CANT1 RYR1

2.54e-06199456CID000023982
Drugbutamben

CACNA1A CACNA1B CACNA1E

3.23e-0615453CID000002482
Druglamotrigine

CACNA1A CACNA1B CACNA1E RYR1 SCN4A

3.27e-06116455CID000003878
Drugnorcepharadione B

CACNA1B CACNA1E

3.82e-062452CID000189168
Drugaristolactam AII

CACNA1B CACNA1E

3.82e-062452CID000148657
Drugalkosin

CACNA1B CACNA1E

3.82e-062452CID005488638
Drugpiperolactam A

CACNA1B CACNA1E

3.82e-062452CID003081016
Drugpentasulfane

CACNA1A CACNA1B CACNA1E

3.97e-0616453CID000448216
Drugphenytoin

CACNA1A CACNA1B CACNA1E CTSB RYR1 SCN4A

4.40e-06219456CID000001775
DrugCinildipine

CACNA1A CACNA1B CACNA1E RYR1

4.54e-0656454CID000002752
Drugbepridil

CACNA1A CACNA1B CACNA1E RYR1 SCN4A

4.90e-06126455CID000002351
Drugnilvadipine

CACNA1A CACNA1B CACNA1E RYR1

5.99e-0660454CID000004494
DrugIAA-94

CACNA1A CACNA1B CACNA1E RYR1

6.40e-0661454CID000003667
DrugN6-Me-dAdo

CACNA1A CACNA1B CACNA1E

6.84e-0619453CID000168948
Drugpranidipine

CACNA1A CACNA1B CACNA1E

6.84e-0619453CID006436048
Druglercanidipine

CACNA1A CACNA1B CACNA1E RYR1

7.28e-0663454CID000065866
Drugisovalerate

CACNA1A CACNA1B CACNA1E RYR1 TNRC6A

9.09e-06143455CID000010430
Druggallopamil

CACNA1A CACNA1B CACNA1E RYR1

9.32e-0667454CID000001234
DrugAC1L2AC7

CACNA1A CACNA1B CACNA1E RYR1

1.05e-0569454CID000068733
Drugbarium

CACNA1A KCNK5 CACNA1B CACNA1E CEACAM5

1.07e-05148455CID000104810
DrugLY320135

CACNA1A CACNA1B CACNA1E

1.24e-0523453CID005311257
Drugalpha-conotoxin SI

CACNA1A CACNA1B CACNA1E

1.24e-0523453CID000163979
Drugprocaine

CACNA1A CACNA1B CACNA1E RYR1 SCN4A

1.26e-05153455CID000004914
DrugCAS 298-57-7

CACNA1A CACNA1B CACNA1E RYR1

1.31e-0573454CID000002761
Drugethosuximide

CACNA1A CACNA1B CACNA1E RYR1

1.38e-0574454CID000003291
Drugglufosinate

CACNA1A CACNA1B CACNA1E RYR1

1.54e-0576454CID000004794
Drugnisoldipine

CACNA1A CACNA1B CACNA1E RYR1

1.71e-0578454CID000004499
DrugN-cyclopentyl-N-cyclobutylformamide

CACNA1A CACNA1B CACNA1E RYR1

1.80e-0579454CID005287890
Druggabapentin

CACNA1A CACNA1B CACNA1E RYR1 SCN4A

2.04e-05169455CID000003446
DrugmAHP

CACNA1A CACNA1B CACNA1E

2.04e-0527453CID000220531
Drugeniluracil

CACNA1A CACNA1B CACNA1E

2.04e-0527453CID000043157
Druglavendustin A

CACNA1A CACNA1B CACNA1E TIAL1 RYR1

2.16e-05171455CID000003894
Drug2,3,4,6-Tetrachloroanisole

GBA3 RYR1

2.29e-054452CID000013647
DrugNSC7524

CACNA1A CACNA1B CACNA1E RYR1 SCN4A

2.91e-05182455CID000005657
Drug2-amino-4-phosphonobutyric acid

CACNA1A CACNA1B CACNA1E RYR1

3.14e-0591454CID000002207
DrugDAPs

CACNA1A CACNA1B CACNA1E CEACAM5

3.28e-0592454CID000146339
DrugTolazoline hydrochloride [59-97-2]; Up 200; 20.4uM; HL60; HG-U133A

CACNA1A SARAF CEACAM5 TIA1 CTSB

3.40e-051884552000_UP
Drug3-aminopropylphosphinic acid

CACNA1A CACNA1B CACNA1E

3.44e-0532453CID006335948
Drugalmagel

CACNA1B CACNA1E

3.81e-055452CID003080942
DrugS 8510

CACNA1A CACNA1B

3.81e-055452CID005488383
Drugdihydropyridine

CACNA1A CACNA1B CACNA1E RYR1 SCN4A

3.86e-05193455CID000104822
Drugisotetrandrine

CACNA1A CACNA1B CACNA1E RYR1

4.03e-0597454CID000005422
Drugfluspirilene

CACNA1A CACNA1B CACNA1E

4.14e-0534453CID000003396
Drugnitrendipine

CACNA1A CACNA1B CACNA1E RYR1

4.20e-0598454CID000004507
Drug3-7a

CACNA1A CACNA1B CACNA1E

4.92e-0536453CID011987860
DrugCP-80

CACNA1A CACNA1B CACNA1E

4.92e-0536453CID000452640
Drugsipatrigine

CACNA1B CACNA1E SCN4A

5.35e-0537453CID000060803
Drugloperamide

CACNA1A CACNA1B CACNA1E RYR1

5.50e-05105454CID000003954
DrugAC1Q7BER

RYR1 HNRNPU

5.70e-056452CID000005702
Drug8-cyclopentyltheophylline

CACNA1A CACNA1B CACNA1E

5.80e-0538453CID000001917
Drug3,4-diaminopyridine

CACNA1A CACNA1B CACNA1E

5.80e-0538453CID000005918
DrugH S Q

GBA3 MFGE8 CEACAM5 CTSB MRC2 B4GALT4

6.31e-05351456CID000000897
DrugAC1L1I54

CACNA1A CACNA1B CACNA1E

7.30e-0541453CID000004426
DrugFk 888

CACNA1A CACNA1B CACNA1E

7.85e-0542453CID000107967
DrugAC1NBU2S

CACNA1A CACNA1B CACNA1E RYR1

8.39e-05117454CID004473765
Drugvalproate

FGA CACNA1A CACNA1B CACNA1E RYR1 SCN4A

9.91e-05381456CID000003121
Drugpimozide

CACNA1A CACNA1B CACNA1E RYR1

1.15e-04127454CID000016362
Drugm-7a

GBA3 RYR1

1.36e-049452CID000029558
Druglanthanum

CACNA1A CACNA1B CACNA1E RYR1

1.50e-04136454CID000023926
Drug4-AP

CACNA1A KCNK5 CACNA1B CACNA1E SCN4A

1.52e-04258455CID000001727
Drugsmilageninoside

CACNA1B CACNA1E

1.70e-0410452CID000197391
Drugbenzyl-EDTA

CEACAM5 CTSB

1.70e-0410452CID000129213
Drugnefiracetam

CACNA1A CACNA1B CACNA1E

1.86e-0456453CID000071157
DrugDantrolene-13C3

CACNA1A CACNA1B CACNA1E RYR1

1.92e-04145454CID000002951
Drugnimodipine

CACNA1A CACNA1B CACNA1E RYR1

1.92e-04145454CID000004497
Drugnicardipine

CACNA1A CACNA1B CACNA1E RYR1

1.92e-04145454CID000004473
DrugBAPNA

FGA CTSB RYR1

1.96e-0457453CID000013494
Druggastrodin

CACNA1B CACNA1E

2.08e-0411452CID000115067
Drug4-aminopiperidine

CACNA1A CACNA1B

2.08e-0411452CID000424361
Drugetorphine

CACNA1A CACNA1B CACNA1E

2.17e-0459453CID000026721
DrugBay K 8644

CACNA1A CACNA1B CACNA1E RYR1

2.19e-04150454CID000002303
DrugU46619

FGA CACNA1A CACNA1B CACNA1E RYR1

2.41e-04285455CID000005618
Drugisobutanol

CACNA1A GBA3 CACNA1B

2.51e-0462453CID000006560
DrugEGTA-AM

CACNA1A CACNA1B CACNA1E

2.51e-0462453CID000121907
Drugmibefradil

CACNA1A CACNA1B RYR1

2.76e-0464453CID000060662
DrugAC1L1DXE

CACNA1A KCNK5 CACNA1B CACNA1E RYR1

3.00e-04299455CID000002548
DrugAC1L1TJF

CACNA1A CACNA1B CACNA1E

3.03e-0466453CID000003377
DrugDCG-IV

CACNA1A CACNA1B CACNA1E

3.31e-0468453CID000115114
DrugAC1L1JG6

CACNA1A CACNA1B

3.42e-0414452CID000005026
Drugfelodipine

CACNA1A CACNA1B CACNA1E RYR1

3.44e-04169454CID000003333
Drugsynthetic pyrethrins

CACNA1A CACNA1B SCN4A

3.75e-0471453CID000002982
Drugflecainide

KCNK5 RYR1 SCN4A

3.75e-0471453CID000003355
Drugverapamil

CACNA1A KCNK5 CACNA1B CACNA1E RYR1 SCN4A

3.85e-04490456CID000002520
DrugBarium

CACNA1A CACNA1B CACNA1E

3.91e-0472453ctd:D001464
Drugpapaverine

CACNA1A CACNA1B CACNA1E RYR1

4.01e-04176454CID000004680
DrugMK-677

FGA CEACAM5 SCN4A

4.07e-0473453CID000178024
Drug1,3-dipropylxanthine

CACNA1A CACNA1B CACNA1E

4.24e-0474453CID000169317
DrugDM-nitrophen

CACNA1A RYR1

4.50e-0416452CID000003083
DrugVerapamil

CACNA1A CACNA1B

4.50e-0416452DB00661
Diseasefamilial hemiplegic migraine 1 (implicated_via_orthology)

CACNA1A CACNA1B CACNA1E

3.31e-093453DOID:0111181 (implicated_via_orthology)
Diseasemigraine (implicated_via_orthology)

CACNA1A CACNA1B CACNA1E

1.32e-084453DOID:6364 (implicated_via_orthology)
Diseasehereditary ataxia (implicated_via_orthology)

CACNA1A CACNA1B CACNA1E

1.16e-077453DOID:0050951 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

CACNA1A CACNA1B CACNA1E LRP1B UNC13A SCN4A

1.77e-07163456DOID:1826 (implicated_via_orthology)
Diseasecolon cancer (implicated_via_orthology)

NANOGP8 NANOG

1.24e-0411452DOID:219 (implicated_via_orthology)
DiseaseCongenital myopathy (disorder)

RYR1 SCN4A

1.49e-0412452C0270960
Diseasecortisol measurement, response to corticosteroid, response to synacthen

GBA3 LRP1B

1.76e-0413452EFO_0005843, EFO_0009175, GO_0031960
Diseaselysophosphatidylcholine 15:0 measurement

PKHD1 LRP1B

2.05e-0414452EFO_0020941
Diseaserespiratory quotient

SCRN1 UNC13A

2.05e-0414452EFO_0005189
DiseaseTremor, Rubral

CACNA1A UROC1

2.69e-0416452C0750940
DiseaseAtaxia, Appendicular

CACNA1A UROC1

2.69e-0416452C0750937
DiseaseAtaxia, Motor

CACNA1A UROC1

2.69e-0416452C0278161
DiseaseAbnormal coordination

CACNA1A UROC1

2.69e-0416452C0520966
DiseaseAtaxia, Truncal

CACNA1A UROC1

2.69e-0416452C0427190
DiseaseAtaxia, Sensory

CACNA1A UROC1

2.69e-0416452C0240991
DiseaseAtaxia

CACNA1A UROC1

6.67e-0425452C0004134
Diseasecreatinine measurement

PKHD1 KCNK5 TNRC6B MFAP4 CTSB ADAMTS7 RYR1

7.19e-04995457EFO_0004518
DiseaseEpileptic encephalopathy

CACNA1A HNRNPU

9.63e-0430452C0543888
DiseasePapillary Renal Cell Carcinoma

CTSB LRP1B RYR1

9.90e-04128453C1306837
DiseaseRenal Cell Carcinoma

CTSB LRP1B RYR1

9.90e-04128453C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

CTSB LRP1B RYR1

9.90e-04128453C1266043
DiseaseChromophobe Renal Cell Carcinoma

CTSB LRP1B RYR1

9.90e-04128453C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

CTSB LRP1B RYR1

9.90e-04128453C1266044
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

CTSB LRP1B RYR1

1.50e-03148453C0279702

Protein segments in the cluster

PeptideGeneStartEntry
NWNYFGWGEQHNDDP

UNC13A

176

Q9UPW8
NSNDASGNTWNWLYF

CACNA1A

326

O00555
FATDWSQQPGLNWYA

ERVPABLB-1

251

P60509
VANSWNTDWGDNGFF

CTSB

296

P07858
YNTNDALGATWNWLY

CACNA1E

316

Q15878
VNGFSNNYWGWGGED

B4GALT4

246

O60513
AFWDFENNNGLGGWN

ADGRG4

2686

Q8IZF6
EAQNTTYLWWVNGQS

CEACAM5

526

P06731
NEKWAYNNSDGGTAW

DFFA

91

O00273
YNTNDAAGNTWNWLY

CACNA1B

321

Q00975
LNYLNWKQSGGTEWT

DMTF1

326

Q9Y222
KYFLNGGWTIQWNGD

ADAMTS7

746

Q9UKP4
GGWTIQWNGDYQVAG

ADAMTS7

751

Q9UKP4
VGTWNTWYGEQDQAV

NIPSNAP2

111

O75323
VDWIGNNLYWTNDGH

LRP1B

606

Q9NZR2
NAWVAGSYGNDQWLQ

MFGE8

276

Q08431
NVQCDWQQKGGTYWV

HERC2

2606

O95714
NGSWAAGYGIWNTAI

ARSJ

431

Q5FYB0
NWRLGQAPANWYNDT

CANT1

76

Q8WVQ1
GQWANLSWELLYATN

PCNX4

1116

Q63HM2
GVAITGNQTFNNWNW

KCNK5

71

O95279
QGWGSTYQAWQQPTQ

FUBP3

486

Q96I24
QQGQFWGQKPWSQHY

HNRNPU

806

Q00839
WNNQAWNSPFYNCGE

NANOG

231

Q9H9S0
LVWQDNTAVNYSNWG

MRC2

1341

Q9UBG0
AWSLLDNFEWNQGYS

GBA3

416

Q9H227
GWWYNNCQAANLNGI

FGA

806

P02671
AWNNYKGYAWGLNEL

MAN1A1

206

P33908
GWSRYWISGNAANGQ

KIRREL2

71

Q6UWL6
QQGGHYSLQVDWYTW

HELZ2

1656

Q9BYK8
VDSYQSWALAGGWNS

HOXB13

166

Q92826
WAFDKIQNNWSYGEN

RYR1

2766

P21817
NWNTWYGEQDQAVHL

NIPSNAP1

111

Q9BPW8
SNDTWYGNDTWYGNE

SCN4A

296

P35499
IQCQNKGWDGYDVQW

SARAF

81

Q96BY9
WNNQAWNSPFYNCGE

NANOGP8

231

Q6NSW7
NLDNLAQLYEGWTAW

SMG1

3646

Q96Q15
HLSYANGINWAQWKG

MFAP4

226

P55083
TWQGVEEGWGGYNNT

PKHD1

2741

P08F94
SYAQSQGWWTGEGEF

SCRN1

206

Q12765
FWNFRLANNTGGWDS

ADGRF5

956

Q8IZF2
WNKLLNWYGCVEGQQ

USP4

101

Q13107
GGNGQVFSNWAQFWL

UROC1

126

Q96N76
SQWGQWSQVYGNPQQ

TIAL1

291

Q01085
FTWGNNINPNNSSGW

TNRC6A

896

Q8NDV7
YGQWGQWYGNAQQIG

TIA1

306

P31483
GGWNDYKNNNSSNWG

TNRC6B

696

Q9UPQ9
WGDPNSYNYKNVNLW

TNRC6B

896

Q9UPQ9