Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH3 DNAH10 DNAH17

3.99e-0518753GO:0008569
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH3 DNAH10 DNAH17

1.56e-0428753GO:0051959
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH3 DNAH10 DNAH17

3.61e-0437753GO:0045505
GeneOntologyCellularComponentaxonemal dynein complex

DNAH3 DNAH10 DNAH17

1.04e-0425773GO:0005858
GeneOntologyCellularComponent9+2 motile cilium

DNAH3 DNAH10 DNAH17 SSX9P SSX3 SSX5

2.47e-04238776GO:0097729
GeneOntologyCellularComponentnuclear outer membrane

SYNE2 UGT2B4 UGT2B7

4.30e-0440773GO:0005640
GeneOntologyCellularComponentinner dynein arm

DNAH3 DNAH10

5.91e-0410772GO:0036156
GeneOntologyCellularComponentSCAR complex

WASF3 WASF1

8.63e-0412772GO:0031209
GeneOntologyCellularComponentdynein complex

DNAH3 DNAH10 DNAH17

1.04e-0354773GO:0030286
MousePhenoabnormal circulating lipid level

SERPINA3 DMXL2 RINT1 OTC NCALD SORBS2 PIEZO2 REEP1 BZW2 FPR2 MGAT4A SERPINB2 PTPN23 GCGR ZC3H12C LRBA KIT CREBBP

8.83e-0613056218MP:0003949
DomainKRAB_RELATED

SSX9P SSX2 SSX3 SSX5

7.75e-0811754PS50806
DomainKrueppel-associated_box-rel

SSX9P SSX2 SSX3 SSX5

1.67e-0713754IPR003655
DomainSSX

SSX2 SSX3 SSX5

1.23e-066753IPR028804
DomainSSXRD

SSX2 SSX3 SSX5

3.43e-068753PF09514
DomainSSXRD_motif

SSX2 SSX3 SSX5

3.43e-068753IPR019041
DomainRecoverin

NCALD GUCA1C HPCAL1

1.73e-0513753IPR028846
DomainSCAR/WAVE_fam

WASF3 WASF1

4.76e-053752IPR028288
DomainZnf_CCCH

TRMT44 ZC3H12B ZC3H12C TIPARP

8.63e-0558754IPR000571
DomainZF_C3H1

TRMT44 ZC3H12B ZC3H12C TIPARP

8.63e-0558754PS50103
DomainGlyco_transf_54

MGAT4D MGAT4A

9.50e-054752PF04666
DomainGlyco_transf_54

MGAT4D MGAT4A

9.50e-054752IPR006759
DomainWD40_repeat_dom

FBXW10B DMXL2 FBXW10 RBBP7 UBR4 LRBA WDR48

1.89e-04297757IPR017986
DomainCNMP_BINDING_1

HCN1 RAPGEF4 SLC9C2

2.84e-0432753PS00888
DomainCNMP_BINDING_2

HCN1 RAPGEF4 SLC9C2

2.84e-0432753PS00889
DomainRNase_Zc3h12a

ZC3H12B ZC3H12C

3.30e-047752PF11977
DomaineIF5C

BZW2 BZW1

3.30e-047752SM00515
DomainRNase_Zc3h12_NYN

ZC3H12B ZC3H12C

3.30e-047752IPR021869
DomainW2

BZW2 BZW1

3.30e-047752PF02020
DomainW2

BZW2 BZW1

3.30e-047752PS51363
DomainW2_domain

BZW2 BZW1

3.30e-047752IPR003307
DomaincNMP

HCN1 RAPGEF4 SLC9C2

3.40e-0434753SM00100
DomaincNMP_binding

HCN1 RAPGEF4 SLC9C2

3.40e-0434753PF00027
DomaincNMP-bd_dom

HCN1 RAPGEF4 SLC9C2

3.71e-0435753IPR000595
DomainCNMP_BINDING_3

HCN1 RAPGEF4 SLC9C2

3.71e-0435753PS50042
DomainG-protein_beta_WD-40_rep

FBXW10B FBXW10 RBBP7 WDR48

3.80e-0485754IPR020472
DomainARM-type_fold

DOCK8 BZW2 UBR4 NOC3L BZW1 LRBA UNC79

4.20e-04339757IPR016024
DomaincNMP-bd-like

HCN1 RAPGEF4 SLC9C2

4.74e-0438753IPR018490
DomainWD40

FBXW10B DMXL2 FBXW10 RBBP7 LRBA WDR48

6.07e-04259756PF00400
DomainWD40

FBXW10B DMXL2 FBXW10 RBBP7 LRBA WDR48

7.26e-04268756SM00320
DomainWD40_repeat

FBXW10B DMXL2 FBXW10 RBBP7 LRBA WDR48

7.84e-04272756IPR001680
DomainWD_REPEATS_1

FBXW10B DMXL2 FBXW10 RBBP7 LRBA WDR48

8.78e-04278756PS00678
DomainWD_REPEATS_2

FBXW10B DMXL2 FBXW10 RBBP7 LRBA WDR48

8.95e-04279756PS50082
DomainWD_REPEATS_REGION

FBXW10B DMXL2 FBXW10 RBBP7 LRBA WDR48

8.95e-04279756PS50294
Domain-

HCN1 RAPGEF4 SLC9C2

9.45e-04487532.60.120.10
DomainRmlC-like_jellyroll

HCN1 RAPGEF4 SLC9C2

1.13e-0351753IPR014710
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH10

1.40e-0314752IPR024317
DomainDynein_HC_stalk

DNAH3 DNAH10

1.40e-0314752IPR024743
DomainDynein_heavy_dom-2

DNAH3 DNAH10

1.40e-0314752IPR013602
DomainDHC_N2

DNAH3 DNAH10

1.40e-0314752PF08393
DomainMT

DNAH3 DNAH10

1.40e-0314752PF12777
DomainAAA_8

DNAH3 DNAH10

1.40e-0314752PF12780
DomainATPase_dyneun-rel_AAA

DNAH3 DNAH10

1.40e-0314752IPR011704
DomainWH2

WASF3 WASF1

1.40e-0314752SM00246
DomainAAA_5

DNAH3 DNAH10

1.40e-0314752PF07728
DomainDHC_fam

DNAH3 DNAH10

1.62e-0315752IPR026983
DomainMIF4-like

BZW2 BZW1

1.62e-0315752IPR016021
DomainDynein_heavy_dom

DNAH3 DNAH10

1.62e-0315752IPR004273
Domain-

BZW2 BZW1

1.62e-03157521.25.40.180
DomainDynein_heavy

DNAH3 DNAH10

1.62e-0315752PF03028
DomainWH2

WASF3 WASF1

1.84e-0316752PF02205
Domain-

FBXW10B DMXL2 FBXW10 RBBP7 LRBA WDR48

2.20e-033337562.130.10.10
DomainWD40/YVTN_repeat-like_dom

FBXW10B DMXL2 FBXW10 RBBP7 LRBA WDR48

2.27e-03335756IPR015943
DomainUDPGT

UGT2B4 UGT2B7

3.18e-0321752PF00201
DomainWH2_dom

WASF3 WASF1

3.18e-0321752IPR003124
DomainUDPGT

UGT2B4 UGT2B7

3.18e-0321752PS00375
DomainUDP_glucos_trans

UGT2B4 UGT2B7

3.18e-0321752IPR002213
DomainEF-hand_1

NCALD GUCA1C HPCAL1 DGKA

3.27e-03152754PF00036
DomainEFh

NCALD GUCA1C HPCAL1 DGKA

3.76e-03158754SM00054
DomainWH2

WASF3 WASF1

4.15e-0324752PS51082
PathwayREACTOME_PARACETAMOL_ADME

SULT2A1 UGT2B4 UGT2B7 ABCC5

1.78e-0539574MM15695
PathwayWP_INTERACTOME_OF_POLYCOMB_REPRESSIVE_COMPLEX_2_PRC2

SETX RBBP7 STK38

3.38e-0516573M39484
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH3 DNAH10 DNAH17

1.71e-0427573M47755
Pubmed

Heterogeneous expression of the SSX cancer/testis antigens in human melanoma lesions and cell lines.

SSX2 SSX3 SSX5

4.17e-08477310749136
Pubmed

The SSX gene family: characterization of 9 complete genes.

SSX9P SSX2 SSX3 SSX5

1.29e-072177412216073
Pubmed

The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP.

SSX2 SSX3 SSX5

5.80e-07877312007189
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

ACSL4 FBXW10B DMXL2 FBXW10 DNAH10 SULT2A1 RBBP7 DNAH17 STK38 SUV39H2 CREBBP

6.14e-07730771134857952
Pubmed

Identification and characterization of mouse SSX genes: a multigene family on the X chromosome with restricted cancer/testis expression.

SSX9P SSX3 SSX5

8.68e-07977314611804
Pubmed

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.

SETX DNAH10 SYNE2 RAPGEF4 STK38 ZC3H12B KIT

2.82e-0627777730745168
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH3 DNAH10 DNAH17

3.73e-06147739373155
Pubmed

Expression of cancer-testis antigen (CTA) in tumor tissues and peripheral blood of Chinese patients with hepatocellular carcinoma.

SSX2 SSX5

4.84e-06277216546222
Pubmed

Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identification of 5-hydroxytryptamine as a substrate.

UGT2B4 UGT2B7

4.84e-06277210222050
Pubmed

FBXW10 promotes hepatocarcinogenesis in male patients and mice.

FBXW10B FBXW10

4.84e-06277231400758
Pubmed

Substrate specificity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7. Identification of a critical aromatic amino acid residue at position 33.

UGT2B4 UGT2B7

4.84e-06277217263731
Pubmed

Translation regulatory factor BZW1 regulates preimplantation embryo development and compaction by restricting global non-AUG Initiation.

BZW2 BZW1

4.84e-06277236333315
Pubmed

Translational autoregulation of BZW1 and BZW2 expression by modulating the stringency of start codon selection.

BZW2 BZW1

4.84e-06277229470543
Pubmed

Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.

FBXW10B FBXW10

4.84e-06277237450367
Pubmed

Single nucleotide polymorphisms and haplotype frequencies of UGT2B4 and UGT2B7 in a Japanese population.

UGT2B4 UGT2B7

4.84e-06277215319348
Pubmed

Rapid WAVE dynamics in dendritic spines of cultured hippocampal neurons is mediated by actin polymerization.

WASF3 WASF1

4.84e-06277216190876
Pubmed

The Association Between WAVE1 and -3 and the ARP2/3 Complex in PC 3 Cells.

WASF3 WASF1

4.84e-06277226977009
Pubmed

Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.

SULT2A1 UGT2B4 UGT2B7

8.31e-061877320056724
Pubmed

Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells.

SETX RBBP7 STK38

8.31e-061877320064376
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

DMXL2 SYNE2 WASF3 PTPN23 MED13L WDR48

1.11e-0522577612168954
Pubmed

Deficiency in Fpr2 results in reduced numbers of Lin-cKit+Sca1+ myeloid progenitor cells.

FPR2 KIT

1.45e-05377230018139
Pubmed

Human oncoprotein 5MP suppresses general and repeat-associated non-AUG translation via eIF3 by a common mechanism.

BZW2 BZW1

1.45e-05377234260931
Pubmed

Genomic organization and expression profile of the human and mouse WAVE gene family.

WASF3 WASF1

1.45e-05377212856283
Pubmed

Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13.

UGT2B4 UGT2B7

1.45e-0537727835904
Pubmed

Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions .

UGT2B4 UGT2B7

1.45e-05377229138287
Pubmed

CIP4 is a new ArgBP2 interacting protein that modulates the ArgBP2 mediated control of WAVE1 phosphorylation and cancer cell migration.

SORBS2 WASF1

1.45e-05377219631450
Pubmed

SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development.

WASF3 WASF1

1.45e-0537729732292
Pubmed

WAVE/Scars in platelets.

WASF3 WASF1

1.45e-05377215280206
Pubmed

Characterization of the WAVE1 knock-out mouse: implications for CNS development.

WASF3 WASF1

1.45e-05377212716942
Pubmed

SSX2-4 expression in early-stage non-small cell lung cancer.

SSX2 SSX3

1.45e-05377224645645
Pubmed

Methadone inhibits CYP2D6 and UGT2B7/2B4 in vivo: a study using codeine in methadone- and buprenorphine-maintained subjects.

UGT2B4 UGT2B7

1.45e-05377222092298
Pubmed

Expression and subcellular localization of WAVE isoforms in the megakaryocyte/platelet lineage.

WASF3 WASF1

1.45e-05377215670045
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ACSL4 RINT1 NCALD HPCAL1 KTN1 SYNE2 UBR4 NOC3L SCN9A DGKA ABCC5 MYBPC2 RPL18A

1.57e-051442771335575683
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

ACSL4 DMXL2 RINT1 KTN1 SYNE2 FLCN LRBA PIGU

1.61e-0550477834432599
Pubmed

An inhibitor of the acetyltransferases CBP/p300 exerts antineoplastic effects on gastrointestinal stromal tumor cells.

KIT CREBBP

2.89e-05477227633918
Pubmed

Sox17-mediated expression of adherent molecules is required for the maintenance of undifferentiated hematopoietic cluster formation in midgestation mouse embryos.

ESAM KIT

2.89e-05477232891959
Pubmed

ArgBP2-dependent signaling regulates pancreatic cell migration, adhesion, and tumorigenicity.

SORBS2 WASF1

2.89e-05477218559503
Pubmed

Neutrophils establish rapid and robust WAVE complex polarity in an actin-dependent fashion.

WASF3 WASF1

2.89e-05477219200726
Pubmed

The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery.

WASF3 WASF1

2.89e-05477217664349
Pubmed

Pin1 Regulates IL-5 Induced Eosinophil Polarization and Migration.

BZW2 BZW1

2.89e-05477233494375
Pubmed

Contribution of polymorphisms in UDP-glucuronosyltransferase and CYP2D6 to the individual variation in disposition of carvedilol.

UGT2B4 UGT2B7

2.89e-05477216849011
Pubmed

Histone binding protein RbAp48 interacts with a complex of CREB binding protein and phosphorylated CREB.

RBBP7 CREBBP

2.89e-05477210866654
Pubmed

A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages.

ZC3H12B ZC3H12C

2.89e-05477218178554
Pubmed

Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.

DNAH3 DNAH10

2.89e-05477211175280
Pubmed

Spermatogonia-dependent expression of testicular genes in mice.

SERPINA3 PTPN23 KIT

3.66e-052977312051830
Pubmed

Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and induces ATF4 translation through delayed re-initiation.

BZW2 BZW1

4.82e-05577227325740
Pubmed

FBXW10-S6K1 promotes ANXA2 polyubiquitination and KRAS activation to drive hepatocellular carcinoma development in males.

FBXW10B FBXW10

4.82e-05577237277019
Pubmed

WAVE2 is required for directed cell migration and cardiovascular development.

WASF3 WASF1

4.82e-05577212879075
Pubmed

UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients.

UGT2B4 UGT2B7

4.82e-05577215318931
Pubmed

FBP11 regulates nuclear localization of N-WASP and inhibits N-WASP-dependent microspike formation.

WASF3 WASF1

4.82e-05577214697212
Pubmed

SSX: a multigene family with several members transcribed in normal testis and human cancer.

SSX3 SSX5

4.82e-0557729378559
Pubmed

Diversification of stem cell molecular repertoire by alternative splicing.

BRIX1 DOCK8 KTN1

6.49e-053577316183747
Pubmed

HIV-1 Nef drives macrophages into hiding.

WASF3 WASF1

7.22e-05677225745180
Pubmed

HIV-1 reprograms the migration of macrophages.

WASF3 WASF1

7.22e-05677225527710
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ACSL4 KTN1 SYNE2 UBR4 FLCN PIGU WASF1 CREBBP

8.49e-0563877831182584
Pubmed

Weak activity of UDP-glucuronosyltransferase toward Bisphenol analogs in mouse perinatal development.

UGT2B4 UGT2B7

1.01e-04777226074487
Pubmed

A role for Piezo2 in EPAC1-dependent mechanical allodynia.

PIEZO2 SCN9A

1.01e-04777223575686
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

ACSL4 RINT1 SETX KTN1 UBR4 THUMPD1 KIT WASF1 CREBBP

1.16e-0485777925609649
Pubmed

Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex.

WASF3 WASF1

1.34e-04877210381382
Pubmed

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.

UGT2B4 UGT2B7

1.34e-04877232093886
Pubmed

Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms.

UGT2B4 UGT2B7

1.34e-04877218052087
Pubmed

Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex.

WASF3 WASF1

1.34e-04877211146629
Pubmed

Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine.

UGT2B4 UGT2B7

1.34e-04877210748067
Pubmed

The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.

UGT2B4 UGT2B7

1.34e-04877218719240
Pubmed

Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.

UGT2B4 UGT2B7

1.34e-04877220142249
Pubmed

Neurodevelopmental disorder-associated CYFIP2 regulates membraneless organelles and eIF2α phosphorylation via protein interactors and actin cytoskeleton.

WASF3 WASF1

1.72e-04977238981622
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

DMXL2 NCALD SORBS2 REEP1 HPCAL1 HCN1 KTN1 UBR4 WASF1 RPL18A

2.05e-041139771036417873
Pubmed

Identification of Ca2+-dependent binding partners for the neuronal calcium sensor protein neurocalcin delta: interaction with actin, clathrin and tubulin.

NCALD HPCAL1

2.15e-041077211964161
Pubmed

Protein kinase CK2-mediated phosphorylation of HDAC2 regulates co-repressor formation, deacetylase activity and acetylation of HDAC2 by cigarette smoke and aldehydes.

RBBP7 CREBBP

2.15e-041077220388487
Pubmed

The EHEC-host interactome reveals novel targets for the translocated intimin receptor.

NCALD HPCAL1

2.15e-041077225519916
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

DMXL2 SORBS2 HCN1 RAPGEF4 WASF1

2.43e-0425177527507650
Pubmed

Defining the membrane proteome of NK cells.

ACSL4 DOCK8 BZW2 KTN1 UBR4 DGKA BZW1 LRBA PIGU RPL18A

2.50e-041168771019946888
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

RINT1 KTN1 SYNE2 STK38 BZW1 LRBA PIGU

2.68e-0456877737774976
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

DMXL2 SORBS2 HCN1 KTN1 SYNE2 UBR4 RAPGEF4 WASF1 UNC79

2.76e-0496377928671696
Pubmed

The DNA sequence of the human X chromosome.

OTC ZC3H12B SSX9P SSX2 SSX3 SSX5

2.91e-0440777615772651
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT2B4 UGT2B7

3.15e-041277220308471
Pubmed

A Prox1 enhancer represses haematopoiesis in the lymphatic vasculature.

ESAM KIT

3.15e-041277236697821
Pubmed

Detoxification enzyme polymorphisms are not involved in duodenal adenomatosis in familial adenomatous polyposis.

UGT2B4 UGT2B7

3.15e-041277218161889
Pubmed

Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia.

SUV39H2 CREBBP

3.15e-041277221402781
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

SETX UBR4 STK38 MED13L WDR48

3.52e-0427277531010829
Pubmed

A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2.

OTC KIT

3.71e-04137728625802
Pubmed

WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination.

WASF3 WASF1

3.71e-041377216723544
Pubmed

Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.

UGT2B4 UGT2B7 ABCC5

4.32e-046677319898482
Pubmed

Identifying genes differentially expressed between PGCs and ES cells reveals a role for CREB-binding protein in germ cell survival.

KIT CREBBP

4.33e-041477217936260
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

BRIX1 ACSL4 RINT1 OTC KTN1 SYNE2 UBR4 THUMPD1 PIGU ME2 RPL18A

4.42e-041496771132877691
Pubmed

Distinct nuclear and cytoplasmic assemblies and interactomes of the mammalian CTLH E3 ligase complex.

BRIX1 SERPINA3 KTN1 RPL18A

5.28e-0416777435833506
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

FAIM DMXL2 SORBS2 HCN1 UBR4 RAPGEF4 ABCC5 LRBA MED13L CREBBP

5.30e-041285771035914814
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

BRIX1 RBBP7 SYNE2 UBR4 NOC3L ME2 RPL18A

6.15e-0465377722586326
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

BRIX1 ACSL4 BZW2 RBBP7 UBR4 PTPN23 RPL18A

6.84e-0466577730457570
Pubmed

SARS-CoV-2 ORF8 Protein Induces Endoplasmic Reticulum Stress-like Responses and Facilitates Virus Replication by Triggering Calnexin: an Unbiased Study.

UBR4 STK38

7.23e-041877236877072
Pubmed

Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.

RBBP7 KTN1 STK38 UNC79 RPL18A

7.45e-0432177532098917
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

DMXL2 RBBP7 KTN1 SYNE2 UBR4 PTPN23

8.40e-0449877636634849
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

SORBS2 DNAH17

8.96e-042077221689717
Pubmed

Tagging genes with cassette-exchange sites.

RINT1 UBR4 FLCN BZW1 CREBBP

9.02e-0433577515741177
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

SULT2A1 UGT2B4 UGT2B7 ABCC5

9.07e-0419377419343046
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SYNE2 UBR4 BZW1

9.68e-048777312465718
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

BZW2 KTN1 STK38 ABCC5 PTPN23 BZW1 LRBA

9.86e-0470877739231216
Pubmed

Zfp296 negatively regulates H3K9 methylation in embryonic development as a component of heterochromatin.

KIT SUV39H2

1.09e-032277228963472
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

DNAH3 OTC SETX HCN1 KTN1 UBR4 DGKA

1.23e-0373677729676528
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

BRIX1 SORBS2 RBBP7 CREBBP RPL18A

1.26e-0336177530344098
Cytoband4q13

UGT2B4 UGT2B7

2.87e-04157724q13
CytobandEnsembl 112 genes in cytogenetic band chrXp11

OTC SSX9P SSX2 SSX3 SSX5

4.43e-04377775chrXp11
CytobandXp11.23

SSX9P SSX3 SSX5

5.62e-0495773Xp11.23
GeneFamilyDyneins, axonemal

DNAH3 DNAH10 DNAH17

1.76e-0517553536
GeneFamilyWD repeat domain containing

FBXW10B DMXL2 FBXW10 RBBP7 LRBA WDR48

1.40e-04262556362
GeneFamilyMannosyl-glycoprotein N-acetylglucosaminyltransferases

MGAT4D MGAT4A

3.23e-049552435
GeneFamilyWD repeat domain containing|F-box and WD repeat domain containing

FBXW10B FBXW10

4.91e-0411552559
GeneFamilyWiskott-Aldrich Syndrome protein family

WASF3 WASF1

1.06e-031655214
GeneFamilyUDP glucuronosyltransferases

UGT2B4 UGT2B7

4.25e-0332552363
GeneFamilyEF-hand domain containing

NCALD GUCA1C HPCAL1 DGKA

4.41e-03219554863
GeneFamilyZinc fingers CCCH-type

ZC3H12B ZC3H12C

5.07e-033555273
GeneFamilySerpin peptidase inhibitors

SERPINA3 SERPINB2

5.65e-0337552739
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

ACSL4 DMXL2 SETX HPCAL1 SYNE2 WASF3 SERPINB2 MED13L WASF1 ME2 CREBBP TIPARP

6.20e-068567612M4500
CoexpressionNAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP

BRIX1 ACSL4 DMXL2 SETX KTN1 SYNE2 MGAT4A NOC3L SCN9A DGKA THUMPD1 BZW1 LRBA WASF1

9.13e-0612157614M41122
CoexpressionGSE17580_TREG_VS_TEFF_DN

TRMT44 HPCAL1 SYNE2 RAPGEF4 STK38 ME2

2.57e-05200766M3671
CoexpressionOHGUCHI_LIVER_HNF4A_TARGETS_DN

SERPINA3 OTC SULT2A1 UGT2B4 UGT2B7 GCGR

2.64e-05201766MM1294
CoexpressionMARIADASON_REGULATED_BY_HISTONE_ACETYLATION_UP

RINT1 DNAH17 UBR4 ESAM

3.00e-0561764M1559
ToppCellLPS_IL1RA|World / Treatment groups by lineage, cell group, cell type

ACSL4 KTN1 SYNE2 MGAT4A SERPINB2 BZW1 MED13L

5.71e-08200777a02fa5b3c4723a6eaa3c685588666c710478dd25
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SETX KTN1 SYNE2 SCN9A ESAM ZC3H12C

1.31e-0620077679e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellLymphoid-Lymphoid-T_cells_(Cd4+_Tnaive-Tcm)|Lymphoid / shred on cell class and cell subclass (v4)

ANKRD13B SETX BZW2 STK38 DGKA

6.91e-06153775ffb8ac88513e83d3ba01574e60beb5476154372b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SORBS2 SYNE2 MGAT4A STK38 DGKA

1.44e-0517877531c847d7f7aa0f6d820afbb45d507992f5e9dc2f
ToppCellLPS-IL1RA-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NCALD RAPGEF4 SCN9A ESAM ZC3H12C

1.52e-05180775544fb373a3346186ec60afe2cfcf141bb04a1eed
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 DNAH10 SCN9A ANO5 UNC79

1.69e-051847752cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 DNAH10 SCN9A ANO5 UNC79

1.69e-05184775ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 DNAH10 SCN9A ANO5 UNC79

1.69e-051847752b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Tcf7l2_(Entopeduncular_Nucleus_(Ent))--|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FBXW10 CWH43 GUCY2C ANO5

1.81e-059077427865bd63dda0624e62a3b713464a490b588d3ae
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Tcf7l2_(Entopeduncular_Nucleus_(Ent))|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FBXW10 CWH43 GUCY2C ANO5

1.81e-05907748c2eb7444f938faade7c81a60c004252d588c80b
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Tcf7l2_(Entopeduncular_Nucleus_(Ent))-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FBXW10 CWH43 GUCY2C ANO5

1.81e-05907744bc53b521abb79fc53ac912f1dc2e3c55426b2e0
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NCALD RAPGEF4 SCN9A ESAM ZC3H12C

1.97e-05190775474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAPGEF4 SCN9A ESAM ZC3H12C KIT

1.97e-05190775a3c6eec6df052105ab78b7e3c78f94218d5912eb
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-intestinal_crypt_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTC SORBS2 BZW2 RBBP7 ME2

1.97e-05190775c0ee404d705b0b4f0c6ded4d070ad85eac4b16db
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NCALD RAPGEF4 SCN9A ESAM ZC3H12C

2.07e-05192775c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NCALD RAPGEF4 SCN9A ESAM ZC3H12C

2.12e-05193775a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAPGEF4 SCN9A ESAM ZC3H12C KIT

2.17e-0519477543f92b0533e26633dc94cce554045d641ef8fd76
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAPGEF4 SCN9A ESAM ZC3H12C KIT

2.17e-051947751d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

NCALD SYNE2 MGAT4A RAPGEF4 ESAM

2.23e-0519577550a193475db1bb1e05b8590225a553688c372c14
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NCALD SORBS2 HCN1 RAPGEF4 UNC79

2.40e-05198775c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NCALD SORBS2 HCN1 RAPGEF4 UNC79

2.40e-051987756d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SORBS2 REEP1 HCN1 RAPGEF4 UNC79

2.40e-051987754ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SORBS2 REEP1 HCN1 RAPGEF4 UNC79

2.40e-051987750ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SETX KTN1 SYNE2 RAPGEF4 ESAM

2.52e-0520077572ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SETX KTN1 SYNE2 RAPGEF4 ESAM

2.52e-05200775dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SETX KTN1 SYNE2 RAPGEF4 ESAM

2.52e-052007755c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SETX SYNE2 RAPGEF4 SCN9A ESAM

2.52e-0520077589821a264e872ed53e08e9d3609d5cc5c314503e
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SETX KTN1 SYNE2 RAPGEF4 ESAM

2.52e-05200775a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellLPS_anti-TNF-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SETX KTN1 RAPGEF4 SCN9A ESAM

2.52e-052007751d105eeda5a2c51f9a4654ffc79b7e2348ad593b
ToppCellLPS_anti-TNF-Endothelial-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SETX KTN1 RAPGEF4 SCN9A ESAM

2.52e-0520077560d2cbf41f37f1b11eddb4c9d9246c9c1fc5a5af
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NCALD GUCY2C SERPINB2 ANO5

7.42e-05129774cbeeaa554da971ba2e4c4b82c85a1d070a45abb8
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PIEZO2 GUCY2C SERPINB2 MYBPC2

8.85e-051357744451c44f3ad788437f4e2ae81049fbbab53f967e
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PIEZO2 GUCY2C SERPINB2 MYBPC2

8.85e-0513577445f67f33c8320d9fb6dbceae603b564f6a8ffd1e
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BZW2 SYNE2 MGAT4A DGKA

1.40e-04152774405d19b290232bb3e564d61c0cff0cfdd247bdff
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BZW2 SYNE2 MGAT4A DGKA

1.40e-0415277406fa7d8acc8f56de00af9bee17884595b300410e
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

BZW2 SYNE2 MGAT4A DGKA

1.43e-04153774b101cb1bce5db785dab46b6c4f7be9c3efe48b0e
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

BZW2 SYNE2 MGAT4A DGKA

1.43e-04153774487388082bb596809ba1caf9197626b6814792ab
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Matrix_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

PIEZO2 REEP1 ESAM KIT

1.47e-04154774928f49839b046b90c2f942458f3e365ddc4e0bc9
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCGR ZC3H12C LRBA PIGU

1.51e-04155774441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCellCOVID-19_Severe-Lymphoid_T/NK-dn_T|COVID-19_Severe / Disease group, lineage and cell class

BZW2 SYNE2 MGAT4A DGKA

1.55e-0415677483f25683e0f55472b56f915ee176fc05efc33a31
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DMXL2 SULT2A1 FPR2 ME2

1.62e-04158774f61ebe3a316e4259387cd9da83707f15e6473cae
ToppCellInt-URO-Lymphocyte-T_NK-CD8_TCM|Int-URO / Disease, Lineage and Cell Type

REEP1 SYNE2 ZC3H12B TRAV36DV7

1.62e-04158774edcc5a26d4571b179f3ae538fed23b661e4677dd
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 SCN9A PKDREJ KLHL31

1.62e-04158774f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 SCN9A PKDREJ KLHL31

1.62e-041587748c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal|GW19 / Sample Type, Dataset, Time_group, and Cell type.

DNAH17 SCN9A TIPARP WDR48

1.66e-04159774f34f2729a3872fbb2939e76ad35d7e25f71b8f57
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal-Unfolded_protein_responsible_cell|GW19 / Sample Type, Dataset, Time_group, and Cell type.

DNAH17 SCN9A TIPARP WDR48

1.66e-04159774929ed98f6c2ad14e8d5af5c6f11a5a3d4b388cf7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ACSL4 FPR2 SERPINB2 KIT

2.15e-04170774be2a34c70665d8d11332b1a70eda03d77cb7f7dd
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTC SERPINB2 ZC3H12B SUV39H2

2.15e-0417077445de83a2231208b8e1f21061d0b91644b4a3ba93
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

OTC PIEZO2 RAPGEF4 WASF1

2.30e-04173774a81992965137195d20fc498f750975303961a828
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBXW10 GUCY2C ZC3H12C RPL18A

2.30e-04173774b6aed736d8480e3a6a5718aabd2fb79b1b75fa48
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

PIEZO2 HCN1 ANO5 UNC79

2.40e-041757744db1a3c284488b3f6de7568363f176d74e2a4587
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

PIEZO2 HCN1 ANO5 UNC79

2.40e-041757748d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIEZO2 REEP1 ESAM KIT

2.50e-041777740e74980a7686c31fcf1476b8f19a3392541df240
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SORBS2 HPCAL1 DGKA WASF1

2.56e-041787745d6297f34e104bacefb25c4e2338b50fe13dd19a
ToppCell(05)_Ciliated-(4)_1wkpi|(05)_Ciliated / shred by cell type and Timepoint

RINT1 DNAH10 STK38 KIT

2.67e-0418077485fc9b164147b28545e2397d32302eea03ef6346
ToppCellLPS-antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAPGEF4 SCN9A ESAM ZC3H12C

2.67e-0418077430cf3c7ee29694eaccb89bf8053a82037d5c9f1d
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

NCALD SYNE2 RAPGEF4 ESAM

2.73e-04181774c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SERPINA3 NCALD SERPINB2 TIPARP

2.73e-04181774ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_A|E18.5-samps / Age Group, Lineage, Cell class and subclass

PIEZO2 REEP1 ESAM KIT

2.78e-04182774ea4f6c8f600ffe9f8e0609637b3371a5ac48ca03
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

PIEZO2 REEP1 ESAM KIT

2.78e-041827747af3b2029b7f55b923d5a4b764d4292f4ea48599
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACSL4 CWH43 GCGR PKDREJ

2.78e-04182774ccfee33de0faebbe69099d4ff3c3971f6a708b99
ToppCellE18.5-samps-Endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

PIEZO2 REEP1 ESAM KIT

2.78e-04182774e2d799e6e7526176a6fe6515b8fbe4d83d3a3ea1
ToppCellfacs-Skin-Telogen-3m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CWH43 SERPINB2 BZW1 TIPARP

2.84e-0418377426b18d1cc5d98f185176e100bafb9bc9081c66f7
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NCALD RAPGEF4 SCN9A ZC3H12C

2.84e-04183774e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE2 MGAT4A STK38 DGKA

2.84e-04183774f2ef110bf29b1a8276ef216238363e542db262c1
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCALD SYNE2 SCN9A KIT

2.90e-04184774a60802e11dcc5f932811260b08a95a32f60f6b19
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCALD SYNE2 SCN9A KIT

2.90e-0418477439c230d32e4259bc784e0edfd9e2884c96898564
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCALD SYNE2 SCN9A KIT

2.90e-041847742a2fb691cc9414ef5b06c26239d2da03d6d7e5c2
ToppCellcritical-Epithelial-Ionocyte|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NCALD RAPGEF4 SCN9A KIT

2.90e-0418477458d36577eff814d46d72f031f3533d71549e3d6e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTC BZW2 DNAH17 RPL18A

2.90e-04184774e7b9c69fc77040c5191ad8089697051e2589c30e
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

SORBS2 UGT2B4 ANO5 KLHL31

2.90e-04184774e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCelldroplet-Bladder-nan-24m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS2 WASF3 RAPGEF4 ESAM

2.96e-0418577490caab8d9361a541c5d5121c97c3f1cdffeeae4a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SORBS2 ESAM PKDREJ KIT

3.02e-04186774a906020a8df6fcca474b278f746c553b177a56b4
ToppCelldroplet-Spleen-nan-3m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETX RAPGEF4 DGKA RPL18A

3.02e-0418677426f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HCN1 RAPGEF4 ANO5 UNC79

3.02e-04186774b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NCALD RAPGEF4 SCN9A ZC3H12C

3.09e-04187774ea9d34bcd3bd1f36745846309ede349773de501a
ToppCelldroplet-Spleen-nan-3m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETX RAPGEF4 DGKA RPL18A

3.09e-0418777491c8e93bde0d1d1a4e324b0acf2afda00f4fb3bf
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SULT2A1 TLCD4 UGT2B4 UGT2B7

3.09e-04187774edb0ab0154542b1c0b3a2c216c4a60f0f06290b3
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAPGEF4 SCN9A ESAM ZC3H12C

3.09e-04187774f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

REEP1 HPCAL1 WASF3 ZC3H12C

3.09e-04187774d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETX RAPGEF4 DGKA RPL18A

3.09e-04187774382db691eb0b3e089e816bed3d6699cc2d4e1bda
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MGAT4A RAPGEF4 ESAM KIT

3.09e-04187774dffa8447c2f3fdacf39a7258c6b4e81a25245041
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAPGEF4 SCN9A ESAM ZC3H12C

3.15e-0418877473f6ec915934154f435a376cb274b058ff7c5f35
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_bronchial_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

RAPGEF4 ESAM ANO5 KIT

3.15e-04188774986aaf31161ec3d1e6c76ee2dd17f44848a21f7e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE2 MGAT4A STK38 DGKA

3.21e-041897749ab77c6fcb573854da5922412f53d2168bda6b58
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE2 MGAT4A STK38 DGKA

3.21e-041897745a9e2ca9a9ee2dc37ab9147a902115a9f1a80169
ToppCellCOVID-19-Heart-EC_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

NCALD SYNE2 RAPGEF4 ESAM

3.21e-04189774fe49852ba15f948b384d6b4c258927c70b741357
ToppCellLPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAPGEF4 SCN9A ESAM KIT

3.21e-04189774e82211b9dc7540e7a183be2cbcfae39fdf503949
ToppCellControl-Endothelial-Endothelial-Alv_Gen_Intermediate|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NCALD RAPGEF4 SCN9A ZC3H12C

3.21e-041897745d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SULT2A1 TLCD4 UGT2B4 UGT2B7

3.21e-041897747899af78b273d9c7f029d52f7e0cf6df4da41f5e
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_bronchial_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

RAPGEF4 ESAM ANO5 KIT

3.21e-04189774033a2be8bbb7bfb437e6f1657b6ca02070c74aa8
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCALD SORBS2 DOCK8 KIT

3.21e-0418977427e5d706f10a6221f314faf642eede15deab3165
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SULT2A1 TLCD4 UGT2B4 UGT2B7

3.28e-04190774a34293601aefe5fb5c400c14091294b9ddaa195b
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CWH43 HCN1 SCN9A UNC79

3.28e-04190774ff3dec5b45c6ea9b5319fb51a0198c6773b7be26
ToppCellControl-T_cells-CD4+_T_cells|Control / group, cell type (main and fine annotations)

DOCK8 SYNE2 MGAT4A DGKA

3.28e-041907740733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCALD SORBS2 CWH43 KIT

3.28e-041907740bad41d19dc515e6bc61e699f4d56664cf2e72fd
ToppCelltumor_Lung-Myeloid_cells-CD207+CD1a+_LCs|Myeloid_cells / Location, Cell class and cell subclass

RAPGEF4 SCN9A ESAM MYBPC2

3.28e-0419077458a6ab70737d719ca9725ac087f20dfe9be0463e
ToppCellLPS-IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAPGEF4 SCN9A ESAM KIT

3.28e-04190774106ea0bb7b99c697ffc5443d72343df2484250c7
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CWH43 HCN1 SCN9A UNC79

3.28e-041907744971857eac9af17d66d673ed2ab7072639f60a10
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIEZO2 RAPGEF4 ESAM KIT

3.34e-0419177438fe60a8570f3c6eb8e8f8646f90d505dfd7d647
DrugBiliton

DNAH3 DNAH10 DNAH17 UGT2B4 UGT2B7

2.47e-0741765CID000002974
Drug3 SA

SETX WASF3 LRBA WASF1

1.06e-0541764CID000449164
DiseaseX-24947 measurement

SULT2A1 UGT2B4 UGT2B7

2.16e-0522733EFO_0800910
Diseasenevus count, cutaneous melanoma

DOCK8 SYNE2 MED13L PIGU

7.83e-0591734EFO_0000389, EFO_0004632
Diseasevitamin D deficiency

SULT2A1 UGT2B4 UGT2B7

1.06e-0437733EFO_0003762
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

HCN1 SCN9A

2.15e-049732C3502809
Diseaseplasma clozapine-to-N-desmethylclozapine ratio measurement

UGT2B4 UGT2B7

2.15e-049732EFO_0600040
Diseasevitamin D measurement, COVID-19

SULT2A1 UGT2B4 UGT2B7

2.47e-0449733EFO_0004631, MONDO_0100096
DiseaseConnective Tissue Diseases

PIEZO2 FLCN

4.63e-0413732C0009782
DiseaseX-19141 measurement

UGT2B4 UGT2B7

4.63e-0413732EFO_0800799
Diseasecutaneous melanoma, hair color

SYNE2 MED13L PIGU

4.95e-0462733EFO_0000389, EFO_0003924
DiseaseLung diseases

DOCK8 FLCN KIT

9.67e-0478733C0024115
DiseaseCholecystitis

SULT2A1 LRBA

1.00e-0319732HP_0001082
Diseaseandrosterone glucuronide measurement

SULT2A1 UGT2B4

1.11e-0320732EFO_0800317
Diseaseanxiety disorder (implicated_via_orthology)

HCN1 SCN9A

1.35e-0322732DOID:2030 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
KKLILGNYKWMNYLE

ACSL4

116

O60488
KSVFLDQMKKFVEWL

BZW2

391

Q9Y6E2
FFYEKISAWITKMEI

ANO5

531

Q75V66
SVFLEQMKKFVEWLK

BZW1

391

Q7L1Q6
VLVNYIFFKAKWEMP

SERPINA3

206

P01011
DKTVEQKMKEILYWF

FBXW10

111

Q5XX13
EWYKKMLDKAFAERI

CREBBP

1501

Q92793
IYFEAKKKQDLYMWL

BRIX1

116

Q8TDN6
AALFYLSMKKKAVVW

DMXL2

1666

Q8TDJ6
KLMYFLVNFWKTNDL

GUCY2C

166

P25092
DWKKLVQMKIYYFAA

PTPN23

236

Q9H3S7
QFLWEKYKRKKEYMN

TIPARP

501

Q7Z3E1
EKLRKAQDFYVEMKW

ANKRD13B

121

Q86YJ7
DKTVEQKMKEILYWF

FBXW10B

111

O95170
FIFMFYKEKPIDWLL

MGAT4A

311

Q9UM21
IAMKWLEFDQKRVKY

KLHL31

236

Q9H511
IEEWQYFYPMVLKKK

MED13L

236

Q71F56
WMNKVKVLFKFTKVD

FLCN

511

Q8NFG4
KYLQKPMYEVQWKVV

KIT

546

P10721
VWLKEMLFYGKYKII

FPR2

266

P25090
EEIKYMLWLSADLKF

OTC

51

P00480
AQVMDFLFEKWKLYG

GCGR

26

P47871
QEKMEQKLKWYFKLY

GUCA1C

86

O95843
KLEQKLKWAFSMYDL

HPCAL1

96

P37235
EKFNSRMKNKLWYFE

DGKA

546

P23743
KFDFKPQKWYMVTIV

LRBA

291

P50851
WLFMKETLYDEVLAK

KTN1

26

Q86UP2
FSDFGLMWYLEELKK

NLRP4

6

Q96MN2
QYIPVKMKSKAFWIF

PIGU

211

Q9H490
RFFLMFYKEKPIDWL

MGAT4D

306

A6NG13
KIWKKNTPFLYDLVM

RBBP7

21

Q16576
VLTYIKFIKMYAWVK

ABCC5

361

O15440
KVIKMNYLKSWFVVD

HCN1

211

O60741
KYAWFFFELLVKSMA

DOCK8

981

Q8NF50
KKYRNELMEKFWIPY

DNAH17

3371

Q9UFH2
IMKQKKEITEEVWYF

DNAH3

3381

Q8TD57
RKEWMFKLVGKETFY

FAIM

41

Q9NVQ4
VMWFFKQKEKEDQVL

ESAM

71

Q96AP7
EAQKKIWMFDKYGLL

ME2

336

P23368
IKSSQFWKYVMDEFK

DNAH10

526

Q8IVF4
FWKYVMDEFKIEVLI

DNAH10

531

Q8IVF4
KLEQKLKWAFSMYDL

NCALD

96

P61601
KFYLENLEQMVKDWK

NOC3L

306

Q8WTT2
MVLVNAVYFKGKWKT

SERPINB2

196

P05120
FRKSEKYMKLFLWLL

CWH43

386

Q9H720
IFFMLWNNKYIKFVM

TAS2R42

256

Q7RTR8
KDFKALWEKYRQYMA

RAPGEF4

141

Q8WZA2
SLWVVKMFYSFQDKL

STK38

146

Q15208
YQELKEKYKEMVKVW

TRMT44

306

Q8IYL2
KDFIKFIEFNAKKMW

SYNE2

4396

Q8WXH0
MYVKKVEKWGINQLF

PKDREJ

861

Q9NTG1
KIFTYIFILEMLLKW

SCN9A

1231

Q15858
EWEKMKVSEKIVYVY

SSX3

36

Q99909
FVKEVLKWKYEMFLN

SETX

1701

Q7Z333
DIKEYVKWMMYWIIF

REEP1

31

Q9H902
NMKFIKKPKSWEEYF

SULT2A1

136

Q06520
KSRFWYFVSQLKKMK

RPL18A

41

Q02543
VDRPKDWYKTMFKQI

SORBS2

91

O94875
EIKKRFKMVYVPNWF

WDR48

406

Q8TAF3
EWEKMKASEKIFYVY

SSX2

36

Q16385
FKIFWQMLVEKLDVY

RINT1

671

Q6NUQ1
IFDMKKWDQFYSEVL

UGT2B4

226

P06133
EWEKMKASEKIIYVY

SSX5

36

O60225
EWEKMKSSEKIIYVY

SSX9P

36

Q7RTT3
KVVKDMEYYLVKWKG

SUV39H2

56

Q9H5I1
YFFDLWKEKMLQDTE

WASF3

156

Q9UPY6
LKFLEYFHKLQVFMW

PIEZO2

921

Q9H5I5
WYKQEKKAPTFLFML

TRAV36DV7

56

A0A075B6V5
IILYWKVIGDKFFIM

TLCD4

106

Q96MV1
WKKFIEERLLMYSFV

ZC3H12B

311

Q5HYM0
LDVEFYTLKKMFWQV

SLC9C2

106

Q5TAH2
YFFDLWKEKMLQDTE

WASF1

156

Q92558
WKKFIDERLLMYSFV

ZC3H12C

366

Q9C0D7
IFDMKKWDQFYSEVL

UGT2B7

226

P16662
FWALVDLIYNMFKKV

UBR4

5096

Q5T4S7
MKKYAETFLEPWFKA

THUMPD1

176

Q9NXG2
CLMKYKQEVWKDLLY

UNC79

246

Q9P2D8
GYFVQKADKKTMEWF

MYBPC2

966

Q14324