Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentpostsynaptic density membrane

LRFN5 LRFN1 LRFN2

2.62e-04157173GO:0098839
GeneOntologyCellularComponentpostsynaptic specialization membrane

LRFN5 LRFN1 LRFN2

5.39e-04201173GO:0099634
GeneOntologyCellularComponentcell surface

MRC2 LRFN5 LRFN1 LRFN2 PXDN

1.52e-031111175GO:0009986
DomainLeu-rich_rpt_typical-subtyp

LRFN5 LRFN1 LRFN2 TLR9 PXDN

2.90e-07177165IPR003591
DomainLRR_TYP

LRFN5 LRFN1 LRFN2 TLR9 PXDN

2.90e-07177165SM00369
DomainLRR

LRFN5 LRFN1 LRFN2 TLR9 PXDN

5.45e-07201165PS51450
DomainCys-rich_flank_reg_C

LRFN5 LRFN1 LRFN2 PXDN

8.78e-0790164IPR000483
DomainLRRCT

LRFN5 LRFN1 LRFN2 PXDN

8.78e-0790164SM00082
DomainLeu-rich_rpt

LRFN5 LRFN1 LRFN2 TLR9 PXDN

2.38e-06271165IPR001611
Domain-

LRFN5 LRFN1 LRFN2 TLR9 PXDN

5.43e-063211653.80.10.10
DomainL_dom-like

LRFN5 LRFN1 LRFN2 TLR9 PXDN

6.04e-06328165IPR032675
DomainLRR_8

LRFN1 LRFN2 TLR9 PXDN

1.13e-05171164PF13855
DomainI-set

LRFN5 LRFN1 LRFN2 PXDN

1.72e-05190164PF07679
DomainIg_I-set

LRFN5 LRFN1 LRFN2 PXDN

1.72e-05190164IPR013098
DomainLRR_1

LRFN5 LRFN2 TLR9 PXDN

3.00e-05219164PF00560
DomainIg_sub2

LRFN5 LRFN1 LRFN2 PXDN

3.95e-05235164IPR003598
DomainIGc2

LRFN5 LRFN1 LRFN2 PXDN

3.95e-05235164SM00408
DomainLRRNT

LRFN5 LRFN2 PXDN

7.47e-0598163IPR000372
DomainLRRNT

LRFN5 LRFN2 PXDN

7.47e-0598163SM00013
DomainIg_sub

LRFN5 LRFN1 LRFN2 PXDN

3.74e-04421164IPR003599
DomainIG

LRFN5 LRFN1 LRFN2 PXDN

3.74e-04421164SM00409
DomainFN3

LRFN5 LRFN1 LRFN2

6.02e-04199163PS50853
DomainIG_LIKE

LRFN5 LRFN1 LRFN2 PXDN

6.68e-04491164PS50835
DomainFN3_dom

LRFN5 LRFN1 LRFN2

6.95e-04209163IPR003961
DomainIg-like_dom

LRFN5 LRFN1 LRFN2 PXDN

7.31e-04503164IPR007110
Domain-

LRFN5 LRFN1 LRFN2 PXDN

2.04e-036631642.60.40.10
DomainIg-like_fold

LRFN5 LRFN1 LRFN2 PXDN

2.56e-03706164IPR013783
Domainfn3

LRFN1 LRFN2

8.28e-03162162PF00041
DomainFN3

LRFN1 LRFN2

1.07e-02185162SM00060
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

LRFN1 LRFN2

1.25e-0420122MM15485
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

LRFN1 LRFN2

1.38e-0421122M27736
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

LRFN1 LRFN2

1.42e-0367122MM15327
Pubmed

The SALM/Lrfn family of leucine-rich repeat-containing cell adhesion molecules.

LRFN5 LRFN1 LRFN2

3.88e-10417321736948
Pubmed

Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo.

LRFN5 LRFN1 LRFN2 PXDN

1.79e-093417418848646
Pubmed

Comparative analysis of structure, expression and PSD95-binding capacity of Lrfn, a novel family of neuronal transmembrane proteins.

LRFN5 LRFN1 LRFN2

3.39e-09717316828986
Pubmed

SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion.

LRFN5 LRFN1 LRFN2

2.22e-072517327480238
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

LRFN5 LRFN1 LRFN2 PXDN

1.03e-0616217425826454
Pubmed

A novel family of adhesion-like molecules that interacts with the NMDA receptor.

LRFN1 LRFN2

4.72e-06717216495444
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

LRFN5 LRFN1 LRFN2

2.44e-0511717317145500
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

MRC2 ABCF3 PXDN FBXO6

1.89e-0461317422268729
InteractionLRFN4 interactions

LRFN1 LRFN2 FBXO6

2.31e-0567173int:LRFN4
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

LRFN5 LRFN1 LRFN2 PXDN

2.84e-06161124593
GeneFamilyFibronectin type III domain containing

LRFN5 LRFN1 LRFN2

1.41e-04160123555
GeneFamilyADAM metallopeptidase domain containing|CD molecules

MRC2 TLR9

2.71e-02394122471
ToppCellTCGA-Head_and_Esophagus-Metastatic|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

ZNF446 TRIT1 SPEF2

7.08e-0610017374d66f84ff546f4b7354f14a38e5178ee77b5a25
ToppCellmild_COVID-19_(asymptomatic)-CD8+_T_naive|World / disease group, cell group and cell class (v2)

MRC2 SH3D19 LRFN1

2.48e-05152173f944743f40ff6ed3a7a096dd53e12d3526c67c4d
ToppCellmild_COVID-19_(asymptomatic)-CD8+_T_naive|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

MRC2 SH3D19 LRFN1

2.63e-05155173e2c901d5c9e42d25d7702e5e8fc19b06f7c817be
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SPEF2 LRFN2 PXDN

3.71e-05174173bc978a2148a0261a4f9d1ca5479b707e224566be
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MRC2 LRFN5 PXDN

3.91e-05177173bd602db857f37869ef76d14c05ef522c509f08ee
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC2 PXDN PCDH12

4.39e-051841731c857126c0ea0671f0d60b048efca288d348d653
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D175|Adult / Lineage, Cell type, age group and donor

SH3D19 PXDN PCDH12

4.60e-05187173f3548817f2fded5978137bb252cb628ac199e4f6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 LRFN5 PXDN

4.75e-0518917371397e993a77d70b2eeede240bdfc7660b558987
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 LRFN5 PXDN

4.75e-051891734eea4759520c312bd17a681034d8074e47093d2b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 LRFN5 PXDN

4.90e-0519117339092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 LRFN5 PXDN

4.90e-05191173bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 LRFN5 PXDN

4.90e-05191173107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 LRFN5 PXDN

4.90e-05191173ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellfacs-BAT-Fat-18m-Endothelial-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRAG1 PXDN PCDH12

4.98e-05192173562e15876088af9189744c9b2de5c4863d7f15fd
ToppCellfacs-BAT-Fat-18m-Endothelial|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRAG1 PXDN PCDH12

4.98e-051921733a99c521c599a289ee2309d97be5ceb99f8aa220
ToppCellfacs-BAT-Fat-18m-Endothelial-endothelial_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRAG1 PXDN PCDH12

4.98e-05192173f9777e0fdd86c2a514f05a42502888329a94b396
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 LRFN5 PXDN

5.13e-05194173ba7f971fb9a19423602da60770f23d9fead4a451
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 LRFN5 PXDN

5.13e-05194173cf0244a29934e515446ac917d3c30672b460fb04
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 LRFN5 PXDN

5.13e-0519417381713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 LRFN5 PXDN

5.13e-05194173e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 LRFN5 PXDN

5.13e-05194173627cffe2d448e74fc5df92e74e5b922a73304137
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-8|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

MRC2 PXDN PCDH12

5.13e-0519417355b97095a7a17a312c616703d291738a0f806339
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

MRC2 LRFN5 SH3D19

5.29e-05196173bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 LRFN5 PXDN

5.37e-05197173e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 LRFN5 PXDN

5.37e-0519717385a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCellFibroblasts-DKK3+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

MRC2 SH3D19 PXDN

5.45e-051981734f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCellCOVID-19-kidney-Fibroblast-2|kidney / Disease (COVID-19 only), tissue and cell type

MRC2 LRFN5 PXDN

5.45e-05198173ca26ca460856b1faaa3e83766da6abdf63af2b51
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MRC2 LRFN5 PXDN

5.45e-051981739541d68a1a6247dbd7161a62644eea6527c2c8ff
ToppCellFibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

MRC2 SH3D19 PXDN

5.54e-0519917340de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCellCOVID-19-kidney-Fibroblast-1|kidney / Disease (COVID-19 only), tissue and cell type

MRC2 LRFN5 PXDN

5.54e-051991739503646ff1ad248181146ce767e9d12e882ec3bd
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)|Striatum / BrainAtlas - Mouse McCarroll V32

MRC2 PCDH12

8.15e-04112172d652e6fae433a6b56bf2a448fba2cf6c5e558905
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Striatum / BrainAtlas - Mouse McCarroll V32

MRC2 PCDH12

8.15e-0411217288fcd0dc12b5c00804381fb7dd59a6a2a9f37419
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-|Striatum / BrainAtlas - Mouse McCarroll V32

MRC2 PCDH12

8.15e-04112172fd4cc5190626cb262aae0a7f04559b0e9757270e
ToppCellCOVID-19_Severe-Neu_3|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients

LRFN5 LRFN2

9.81e-041231724c20c025b6f19f075a13282288fc537e6e186217
ToppCellCOVID-19_Severe-Neu_3|World / 5 Neutrophil clusters in COVID-19 patients

LRFN5 LRFN2

9.97e-0412417254b42ffb161eece4ae308782e43a0e0dc360281e
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)|Cerebellum / BrainAtlas - Mouse McCarroll V32

MRC2 PXDN

1.03e-031261726d5075d659dac7b96e6857f8485a7d2c4105d685
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Cerebellum / BrainAtlas - Mouse McCarroll V32

MRC2 PXDN

1.03e-0312617283f3540683b3b175b10af059ab8898c46eaccc13
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

MRC2 PXDN

1.03e-03126172fd0001a0f3a0a4421f96fd21813c21cf6f01d40e
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

MRC2 PXDN

1.03e-03126172f20424f9baf3c4059cd6b701761e7595400fc47c
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Stem_cells-neuroepithelial-like_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

LRFN5 FBXO6

1.05e-031271729071cd0953c8bb6746dc9cd13d153e3d6ef40b08
ToppCelldroplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l33|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF446 PCDH12

1.20e-03136172a43b3db1754c619d328a26a2ba6af4756629a723
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-matrix_-_mature_3|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CCDC57 PRAG1

1.21e-031371729bfdbc102cdd861996b3c4eac35b606be8af97eb
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-MAIT|GI_small-bowel / Manually curated celltypes from each tissue

WDFY3 PCDH12

1.40e-031471724ba9a86ab7033688a9a2a2dc84c001a49af835b4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRFN5 LRFN2

1.43e-0314917224a7538b54b2a5291503c7493fefed4e45e8d710
ToppCellCerebellum-Endothelial-ENDOTHELIAL_TIP|Cerebellum / BrainAtlas - Mouse McCarroll V32

MRC2 PXDN

1.43e-031491723980fa4f1986a2f164a1826ea043fb71f1d756cd
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRFN5 LRFN2

1.43e-031491727e295b2b82dea0754e98f8cef788e2781e5d641f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRFN5 LRFN2

1.43e-03149172b4f77dc5f9d08b249fe5cd9a0acf86308c528ef4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRFN5 LRFN2

1.43e-03149172cc6224c6b79f43b97adc1ce48ca4906bff2ad318
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-pDC|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRFN2 TLR9

1.49e-031521720c6dd41142e4ca1e54ca41e05e42ed29fbf0e570
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 PXDN

1.55e-0315517282e602f31981c6b48abff2a04b2ab5d26d4462a2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 PXDN

1.55e-03155172979c1d53b435a82c57d16707eed8ba7346326866
ToppCell10x5'-Liver-Myeloid_Mac-Intestinal_macrophages|Liver / Manually curated celltypes from each tissue

MRC2 WDFY3

1.57e-031561729a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRFN5 LRFN2

1.57e-03156172dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRFN5 LRFN2

1.57e-03156172abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF446 ZNF695

1.57e-0315617214e2f693a75f1075f40cc7b16ee430262a5de016
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRFN5 LRFN2

1.61e-03158172e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-2|TCGA-Lung / Sample_Type by Project: Shred V9

LRFN2 ZNF695

1.61e-031581729dea15b28f64206bac0e785df6f36a2cc9010ac7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRFN5 LRFN2

1.61e-03158172d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF695 FBXO6

1.63e-0315917203d77e7fee40262bf0942aab96b273f1c4f5d8e3
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells-pDC|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRFN2 TLR9

1.65e-03160172dee756a2dc9725520d439e7273c489c2284015d8
ToppCelllymphoid-B_cell-pro-B|World / Lineage, cell class and subclass

LRFN2 PXDN

1.67e-0316117223138e579f07d5a6f20d41457cb573b4ac95a4ef
ToppCellInfluenza_Severe-Neutrophil|Influenza_Severe / Disease group and Cell class

LRFN1 WDFY3

1.67e-0316117298c95b1b85d5427415af2ca8fb14849e97f6e8b5
ToppCellAT1_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

ZNF446 PXDN

1.69e-03162172ae2ba4f21f6f6c512006fa531d670b88be7c04c9
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Cilia-bearing_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

MRC2 SPEF2

1.73e-03164172346e1530b4bf30adbcb2f7d64fdfb4cd8df69d7f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIT1 LRFN2

1.75e-031651721703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCelllymphoid-B_cell-pro-B|lymphoid / Lineage, cell class and subclass

LRFN2 PXDN

1.75e-031651728126c2f7810fc6e09b18783aadf6434ae12b0514
ToppCelldroplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPEF2 TLR9

1.77e-031661721ca888ae8168707493f19ee52a89d7c70e6cb51d
ToppCelldroplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPEF2 TLR9

1.77e-031661724cba4ca1aa2321b9ef7cd230932b890d2434a252
ToppCell367C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

PRAG1 MRC2

1.80e-03167172b5d15773be32cd277125fd3b4056a8fefaefa5ec
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

MRC2 PXDN

1.82e-03168172aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRFN5 LRFN2

1.82e-03168172a086c306be430adf0632ba53e98cd8014d2de330
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_mem-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TLR9 PXDN

1.84e-03169172e3ec9468141b6456398dca17dd8eeaabd2462710
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC2 PCDH12

1.84e-0316917287116c33c5ca8cb1862e103e5607b1df4d264569
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_endothelial_cell_-_unspecif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PXDN PCDH12

1.86e-031701726eb86352739e6fd3cb914e9a16505ac629970b66
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRAG1 TRIT1

1.86e-03170172070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 LRFN5

1.88e-031711722a77ed79c6f2e700e789c80451a70ecb31639719
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 LRFN5

1.88e-03171172972fab891135bd755d5526cbc5a963200067b0a6
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRAG1 FBXO6

1.90e-03172172b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCellfacs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRAG1 FBXO6

1.90e-031721722f1673fcb2356684d60871debb0f159aec553a1c
ToppCelllymphoid-B_cell-pro-B|B_cell / Lineage, cell class and subclass

LRFN2 PXDN

1.90e-03172172da1e2e54f442f5c2032c857c4812e9060f2053cd
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC2 PCDH12

1.90e-03172172073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCell10x5'-Lung-Myeloid_Dendritic-Cycling_Dendritic|Lung / Manually curated celltypes from each tissue

TRIT1 ZNF695

1.92e-0317317262e0c18cfed9645e34a9d7029c94a8554f773714
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

ZNF446 WDFY3

1.92e-0317317242c911ed16fabdabef063830e8407192d8bde950
ToppCellsevere_influenza-Neutrophil|World / disease group, cell group and cell class (v2)

LRFN1 WDFY3

1.95e-03174172f9f07436b7d3f190800cd85d229f007032f391e1
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 PXDN

1.97e-0317517212f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCellCaecum-Dendritic_cell-cDC1|Dendritic_cell / Region, Cell class and subclass

ZNF446 TRIT1

1.99e-0317617207cde50e1c18fcc2c5028efe1a087db4ef4d4783
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 WDFY3

1.99e-03176172327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PXDN PCDH12

1.99e-031761725d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCellB_cell_maturation-CD34+_pre-plamsa|World / Lineage and Cell class

LRFN2 PXDN

2.01e-031771723ff06100deee9bee852a52078666999a9f7beaf1
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-|343B / Donor, Lineage, Cell class and subclass (all cells)

ABCF3 PXDN

2.01e-0317717243ba6f12c2fb32698a420bf799d46ac1b558f146
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)|343B / Donor, Lineage, Cell class and subclass (all cells)

ABCF3 PXDN

2.01e-03177172e55d21d4d61a069b9bbe0e7595fbfb7cfbacfd87
ToppCellControl|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPEF2 PCDH12

2.01e-03177172b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRFN2 PXDN

2.04e-03178172b169aa5eaa51730daaec69c6bc58126be1592a50
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5|TCGA-Skin / Sample_Type by Project: Shred V9

MRC2 LRFN5

2.04e-03178172ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 PXDN

2.04e-0317817278a0c6340001a77f5b2d890b6263f574af2e72da
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MRC2 LRFN5

2.04e-03178172d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRFN2 PXDN

2.06e-03179172747a32460b257fffca30527b56a74720eb9c12e4
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

LRFN5 PXDN

2.06e-03179172e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

PXDN PCDH12

2.06e-03179172cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

MRC2 SH3D19

2.06e-03179172dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

PXDN PCDH12

4.39e-045072GAVISH_3CA_METAPROGRAM_ENDOTHELIAL_ENDO_5
ComputationalGenes in the cancer module 26.

TRIT1 TLR9

7.27e-0320772MODULE_26
ComputationalBreast cancer expression clusters.

TRIT1 TLR9

7.97e-0321772MODULE_389
ComputationalGenes in the cancer module 207.

TRIT1 TLR9

8.62e-0322672MODULE_207
DrugCinchonine [118-10-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A

MRC2 WDFY3 ZNF695 PCDH12

1.12e-051941742789_UP
Diseasecolorectal cancer, overall survival

LRFN5 LRFN2

1.26e-0429172EFO_0000638, MONDO_0005575
Diseaseacne

CCDC57 PRAG1

2.32e-03125172EFO_0003894
Diseaseautism spectrum disorder (implicated_via_orthology)

WDFY3 LRFN2

3.41e-03152172DOID:0060041 (implicated_via_orthology)
Diseaseasthma

PRAG1 SPEF2 SH3D19

8.56e-03751173MONDO_0004979
Diseaseinsulin measurement

LRFN5 ZNF695

1.01e-02267172EFO_0004467

Protein segments in the cluster

PeptideGeneStartEntry
DERFIRLVCRELWVC

ABCF3

666

Q9NUQ8
NCRLVCSLWRDLIDL

FBXO6

36

Q9NRD1
RLDREQLCRQWDPCL

PCDH12

91

Q9NPG4
CELLWLRRLSREDDL

LRFN5

246

Q96NI6
LCDLCDRIIIGDREW

TRIT1

396

Q9H3H1
CNCELLWLRRLTRED

LRFN1

256

Q9P244
ECDREALNLRWHCRT

MRC2

111

Q9UBG0
LGLDWQRRCDDIERD

CCDC57

426

Q2TAC2
ADDNCRFLCWSRERL

BVES

221

Q8NE79
DLRDRLWDICDARKE

SPEF2

1111

Q9C093
LERLDSDWCRGRLQD

SH3D19

691

Q5HYK7
RCCLEKLRLRNDWEI

ZNF695

116

Q8IW36
TEEWCQIECELLRER

WDFY3

2341

Q8IZQ1
EECRGRWALRLCLEE

TLR9

896

Q9NR96
RVDLRVWQDCCEDCR

PXDN

1306

Q92626
VDRRRGVELEDWLCC

PRAG1

1371

Q86YV5
REALARLRELCCQWL

ZNF446

41

Q9NWS9
CNCELLWLRRLERDD

LRFN2

246

Q9ULH4
LWLRRLERDDDLETC

LRFN2

251

Q9ULH4