Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE1 SYNE2

3.70e-055392GO:0140444
GeneOntologyMolecularFunctionsemaphorin receptor activity

PLXNA3 PLXNB2

2.42e-0412392GO:0017154
GeneOntologyBiologicalProcessnuclear migration

SYNE1 PTK2 SYNE2

3.06e-0534373GO:0007097
GeneOntologyBiologicalProcessnucleus localization

SYNE1 PTK2 SYNE2

6.69e-0544373GO:0051647
GeneOntologyCellularComponentpostsynapse

CACNA1E HTR3D RPSA SCRIB MAGEE1 PCDH10 MYO9A SYNE1 PTK2

8.40e-051018399GO:0098794
GeneOntologyCellularComponentsynaptic membrane

CACNA1E HTR3D SCRIB MAGEE1 RIMS2 PCDH10 SYNE1

8.96e-05583397GO:0097060
GeneOntologyCellularComponentpostsynaptic membrane

CACNA1E HTR3D SCRIB MAGEE1 PCDH10 SYNE1

9.68e-05405396GO:0045211
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE1 SYNE2

1.85e-0411392GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE1 SYNE2

1.85e-0411392GO:0034993
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE1 SYNE2

1.85e-0411392GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE1 SYNE2

1.85e-0411392GO:0106094
GeneOntologyCellularComponentsemaphorin receptor complex

PLXNA3 PLXNB2

2.61e-0413392GO:0002116
GeneOntologyCellularComponentcell-cell contact zone

SCRIB HAMP PTK2

7.16e-0494393GO:0044291
GeneOntologyCellularComponentnuclear outer membrane

SYNE1 SYNE2

2.53e-0340392GO:0005640
DomainKASH

SYNE1 SYNE2

2.41e-054382PF10541
DomainKASH

SYNE1 SYNE2

2.41e-054382IPR012315
DomainKASH

SYNE1 SYNE2

2.41e-054382SM01249
DomainKASH

SYNE1 SYNE2

2.41e-054382PS51049
DomainPlexin_cytopl

PLXNA3 PLXNB2

1.44e-049382PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA3 PLXNB2

1.44e-049382IPR013548
DomainPlexin

PLXNA3 PLXNB2

1.44e-049382IPR031148
Domain-

PLXNA3 PLXNB2

4.75e-04163821.10.506.10
DomainRasGAP_dom

PLXNA3 PLXNB2

6.04e-0418382IPR001936
DomainRho_GTPase_activation_prot

PLXNA3 PLXNB2 MYO9A

7.57e-0488383IPR008936
DomainActinin_actin-bd_CS

SYNE1 SYNE2

9.93e-0423382IPR001589
DomainACTININ_2

SYNE1 SYNE2

9.93e-0423382PS00020
DomainACTININ_1

SYNE1 SYNE2

9.93e-0423382PS00019
DomainSpectrin

SYNE1 SYNE2

9.93e-0423382PF00435
DomainIPT

PLXNA3 PLXNB2

1.37e-0327382SM00429
DomainSpectrin_repeat

SYNE1 SYNE2

1.58e-0329382IPR002017
DomainTIG

PLXNA3 PLXNB2

1.81e-0331382PF01833
DomainSEMA

PLXNA3 PLXNB2

1.81e-0331382PS51004
DomainSema

PLXNA3 PLXNB2

1.81e-0331382SM00630
DomainSemap_dom

PLXNA3 PLXNB2

1.81e-0331382IPR001627
DomainSema

PLXNA3 PLXNB2

1.81e-0331382PF01403
DomainPlexin_repeat

PLXNA3 PLXNB2

1.92e-0332382IPR002165
DomainPSI

PLXNA3 PLXNB2

1.92e-0332382PF01437
DomainSpectrin/alpha-actinin

SYNE1 SYNE2

1.92e-0332382IPR018159
DomainIPT

PLXNA3 PLXNB2

1.92e-0332382IPR002909
DomainSPEC

SYNE1 SYNE2

1.92e-0332382SM00150
DomainPSI

PLXNA3 PLXNB2

3.61e-0344382IPR016201
DomainPSI

PLXNA3 PLXNB2

3.94e-0346382SM00423
Domain-

CDC20B PLXNA3 PLXNB2 WDR59

4.54e-033333842.130.10.10
DomainWD40/YVTN_repeat-like_dom

CDC20B PLXNA3 PLXNB2 WDR59

4.64e-03335384IPR015943
DomainCH

SYNE1 SYNE2

7.73e-0365382SM00033
DomainCH

SYNE1 SYNE2

8.92e-0370382PF00307
Domain-

SYNE1 SYNE2

9.17e-03713821.10.418.10
DomainCH

SYNE1 SYNE2

9.67e-0373382PS50021
DomainCH-domain

SYNE1 SYNE2

1.02e-0275382IPR001715
Pubmed

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.

SYNE1 SYNE2

1.23e-06239222768332
Pubmed

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

SYNE1 SYNE2

1.23e-06239217761684
Pubmed

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.

SYNE1 SYNE2

1.23e-06239231578382
Pubmed

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

SYNE1 SYNE2

1.23e-06239211792814
Pubmed

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.

SYNE1 SYNE2

1.23e-06239224931616
Pubmed

Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.

SYNE1 SYNE2

1.23e-06239217267447
Pubmed

Nesprins: tissue-specific expression of epsilon and other short isoforms.

SYNE1 SYNE2

1.23e-06239224718612
Pubmed

Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

SYNE1 SYNE2

1.23e-06239224586179
Pubmed

Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.

SYNE1 SYNE2

3.67e-06339217462627
Pubmed

Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.

SYNE1 SYNE2

3.67e-06339210878022
Pubmed

Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.

SYNE1 SYNE2

3.67e-06339233472039
Pubmed

Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.

SYNE1 SYNE2

3.67e-06339225516977
Pubmed

The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.

SYNE1 SYNE2

3.67e-06339216079285
Pubmed

The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.

SYNE1 SYNE2

3.67e-06339212408964
Pubmed

Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton.

SYNE1 SYNE2

7.34e-06439219596800
Pubmed

SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.

SYNE1 SYNE2

7.34e-06439216648470
Pubmed

LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.

SYNE1 SYNE2

7.34e-06439223071752
Pubmed

Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.

SYNE1 SYNE2

7.34e-06439228716842
Pubmed

Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.

SYNE1 SYNE2

7.34e-06439220108321
Pubmed

Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.

SYNE1 SYNE2

1.22e-05539218396275
Pubmed

LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.

SYNE1 SYNE2

1.22e-05539222632968
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ZC3H7A RPSA SCRIB GTF3C1 MYO9A SERPINB3 WDR59 PTK2 RPL19

1.47e-05135339929467282
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

RPSA PBRM1 SCRIB GTF3C1 PLXNB2 SYNE1 SYNE2 RPL19

1.50e-05102439824711643
Pubmed

Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.

SYNE1 SYNE2

1.83e-05639233058875
Pubmed

TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.

SYNE1 SYNE2

1.83e-05639218827015
Pubmed

Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase.

LAMA3 PPIG RPSA SCRIB

2.31e-0514839422898364
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

PLXNA3 CACNA1E ZC3H7A GTF3C1 TMCO1 RIMS2 SYNE1 SYNE2 RPL19

2.43e-05144239935575683
Pubmed

Rebuilding essential active zone functions within a synapse.

CACNA1E RIMS2

2.56e-05739235176221
Pubmed

The expression of plexins during mouse embryogenesis.

PLXNA3 PLXNB2

3.42e-05839215661641
Pubmed

FAK-MAPK-dependent adhesion disassembly downstream of L1 contributes to semaphorin3A-induced collapse.

PLXNA3 PTK2

3.42e-05839218464795
Pubmed

An ENU-mutagenesis screen in the mouse: identification of novel developmental gene functions.

SCRIB PLXNB2

3.42e-05839221559415
Pubmed

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism.

HAMP RPL19

4.39e-05939219252486
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

PLXNA3 MEST MGAT5 SCRIB GNPTG GTF3C1 PLXNB2 RPL19

4.68e-05120139835696571
Pubmed

Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle.

SYNE1 SYNE2

5.48e-051039228533284
Pubmed

Nuclear membrane proteins with potential disease links found by subtractive proteomics.

SYNE1 SYNE2

5.48e-051039212958361
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

RPSA DNAH10 SYNE1 SYNE2

5.75e-0518739426460568
Pubmed

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.

RPSA TMCO1 PLXNB2 SYNE2 RPL19

6.04e-0537539532788342
Pubmed

TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN.

CACNA1E RPSA SERPINB3 ALDH16A1 RPL19

6.59e-0538239537249651
Pubmed

A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.

SYNE1 SYNE2

6.70e-051139222826121
Pubmed

Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.

PLXNA3 PLXNB2

8.03e-051239221270798
Pubmed

KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development.

SYNE1 SYNE2

9.48e-051339221177258
Pubmed

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.

PLXNA3 PLXNB2

9.48e-051339210520995
Pubmed

A functional reference map of the RNF8 interactome in cancer.

RPSA PBRM1 SERPINB3 RPL19

1.04e-0421839435831895
Pubmed

SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.

SYNE1 SYNE2

1.11e-041439219874786
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

CACNA1E RPSA RIMS2 RPL19

1.30e-0423139416452087
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

LAMA3 MEST RPSA GTF3C1 MYO9A RPL19

1.54e-0473239634732716
Pubmed

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.

PLXNA3 PLXNB2

1.65e-041739211683995
Pubmed

Semaphorin signaling facilitates cleft formation in the developing salivary gland.

PLXNA3 PLXNB2

1.65e-041739217626059
Pubmed

Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.

GTF3C1 RIMS2 PLXNB2 PTK2

1.73e-042493949371744
Pubmed

mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.

GTF3C1 MYO9A SYNE2

1.84e-049839334943047
Pubmed

A human MAP kinase interactome.

LAMA3 ZC3H7A MYO9A SYNE1 PTK2

2.03e-0448639520936779
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

RPSA PBRM1 GTF3C1 SERPINB3

2.43e-0427239431010829
Pubmed

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

PBRM1 DNAH10

2.54e-042139222479202
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

CACNA1E RIMS2 SYNE1 PTK2

2.75e-0428139428706196
Pubmed

A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.

PLXNA3 PLXNB2

3.33e-042439228893946
Pubmed

Lem2 is essential for cardiac development by maintaining nuclear integrity.

SYNE1 SYNE2

5.95e-043239237067297
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CACNA1E PBRM1 SCRIB SYNE1 PTK2 SYNE2

6.63e-0496339628671696
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

RPSA SCRIB PLXNB2 SERPINB3 ALDH16A1 SYNE2 RPL19

7.28e-04136739732687490
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RPSA PBRM1 GTF3C1 SYNE2 RPL19

7.80e-0465339522586326
Pubmed

Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.

SCRIB SYNE2

7.96e-043739227565344
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

DNAH10 SYNE1 ALDH16A1

8.90e-0416839330631154
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RPSA PBRM1 GTF3C1 DNAH10 SERPINB3 SYNE1 RPL19

9.29e-04142539730948266
Pubmed

Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.

PPIG PBRM1

1.03e-034239235705031
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE1 SYNE2

1.59e-0543021252
GeneFamilyPlexins

PLXNA3 PLXNB2

9.51e-059302683
ToppCell10x5'-Liver-Lymphocytic_T_CD8-Tem/emra_CD8|Liver / Manually curated celltypes from each tissue

RPSA GTF3C1 SYNE1 SYNE2 RPL19

8.00e-071983952fc2a4638c458ae793ac090a29d27b75fc9e6af6
ToppCellsevere_COVID-19-MAIT|severe_COVID-19 / disease group, cell group and cell class (v2)

MSANTD1 ANKMY1 GTF3C1 SYNE2

1.07e-05157394175f637e9707836bd63b5c2ccc9d4eb601c05b9e
ToppCellLeuk-UTI-Lymphocyte-T_NK-gdT|Leuk-UTI / Disease, Lineage and Cell Type

GTF3C1 DNAH10 SYNE1 SYNE2

1.09e-05158394c4b0af25608cee3d0d2b0193f5ff45d9dc87078b
ToppCellICU-SEP-Lymphocyte-T_NK-CD4_TEM|ICU-SEP / Disease, Lineage and Cell Type

FSCN2 RPSA SYNE2 RPL19

1.18e-05161394ae6c9afc3c928124993686a82d37d23138322bc1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RIMS2 MYO9A SYNE1 SYNE2

2.08e-05186394f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GTF3C1 TMCO1 SYNE1 SYNE2

2.21e-05189394bed43041e6f8ba19787150a6aaa492f2656135d9
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-MAIT|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

RPSA GTF3C1 ZSWIM4 SYNE2

2.35e-05192394892789bdba150ef9a8a0012de52545f2ff6a31f6
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-MAIT-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPSA GTF3C1 ZSWIM4 SYNE2

2.35e-0519239424ea8fdcca2695aeb2e4b88161184124b7d332c1
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-MAIT-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RPSA GTF3C1 ZSWIM4 SYNE2

2.35e-0519239444f440ee3842fe14665c4cd4f2aa48e7a5bbd9a8
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD8+_T-MAIT|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPSA GTF3C1 ZSWIM4 SYNE2

2.35e-051923948d50ad8cfe3cb9f183188b08457756af0ce56ffe
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA3 MYO9A SYNE1 SYNE2

2.40e-05193394f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA3 MYO9A SYNE1 SYNE2

2.40e-0519339442df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellICU-SEP-Lymphocyte-T_NK-CD8_TEM|ICU-SEP / Disease, Lineage and Cell Type

RPSA SYNE1 SYNE2 RPL19

2.45e-051943945dbf0e3d8ccc389220f1fceaa2e99c85a1c4d818
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPSA SYNE1 SYNE2 RPL19

2.45e-05194394cb9f67366cfa39bd7dfd3b7a6e4672af93350958
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA3 MYO9A SYNE1 SYNE2

2.45e-05194394e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellHealthy-CD4+_CTL|World / disease group, cell group and cell class

RPSA SYNE1 SYNE2 RPL19

2.55e-051963946a623eeb2ba8d4e16543820bcbba41eecbd00ed2
ToppCellHealthy/Control-gd_T|World / Disease group and Cell class

RPSA GTF3C1 SYNE1 SYNE2

2.55e-05196394b982c84552e7efbff2be861f0f569f40804f5d88
ToppCellSevere-Lymphoid-T-CCR7+_T|Severe / Condition, Lineage, Cell class and cell subclass

RPSA SYNE1 SYNE2 RPL19

2.60e-051973940489e0b08f3c3ef90b166ea2f26a0b2b12bd2077
ToppCellcontrol-Lymphocytic-CD8_T_cells|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RPSA SYNE1 SYNE2 RPL19

2.60e-05197394c1c47db5e8d1b248bc192556275edd1ce168a953
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_1-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RPSA SYNE1 SYNE2 RPL19

2.60e-05197394b4f801cd48955463285e0c1bb4fc8ea790c631cb
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_1|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

RPSA SYNE1 SYNE2 RPL19

2.60e-05197394821c1df511cc4a286ddc6fa229059561f6f6bade
ToppCellMild-Lymphoid-T-CCR7+_T|Mild / Condition, Lineage, Cell class and cell subclass

RPSA SYNE1 SYNE2 RPL19

2.60e-05197394f23bd8f6ad011730699a5bb7211cd0feeaebc42b
ToppCellCOVID_vent-Lymphocytic-T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

RPSA SYNE1 SYNE2 RPL19

2.60e-05197394ad702e440a74d54cfdcb8bb1c66bd8e0e71ab04e
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPSA SYNE1 SYNE2 RPL19

2.60e-05197394fef3ccfadc06d11244b71395b0a13280841dd368
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LAMA3 PLXNB2 MYO9A SYNE2

2.60e-051973943d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPSA SYNE1 SYNE2 RPL19

2.65e-051983946c375fc7e53ed7b7b0feba459958d177a65f7272
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPSA SYNE1 SYNE2 RPL19

2.65e-051983947df4608e2d841c405565ad9c4f4fa8d8ae3a2be5
ToppCellHealthy_donor|World / disease group, cell group and cell class (v2)

RPSA SYNE1 SYNE2 RPL19

2.65e-051983941ed0b50c9754727a05c27b21f3546bf2e37eef7f
ToppCellICU-SEP-Lymphocyte-T_NK|ICU-SEP / Disease, Lineage and Cell Type

RPSA SYNE1 SYNE2 RPL19

2.65e-0519839403c5493faf3a4e09a5c1b1450c4551f12f699298
ToppCellHealthy_donor-gd_T|World / disease group, cell group and cell class (v2)

RPSA GTF3C1 SYNE1 SYNE2

2.65e-051983940c3475936f148f2c026501c61b43bcb94d320c48
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-gd_T|Leuk-UTI / Disease, condition lineage and cell class

GTF3C1 DNAH10 SYNE1 SYNE2

2.71e-05199394b2c1b9ee764e1246bfa3ecf666ca76ae4ac6c362
ToppCellMild-Lymphoid|Mild / Condition, Lineage, Cell class and cell subclass

RPSA SYNE1 SYNE2 RPL19

2.71e-051993945bf1bf2741ab374b1a914fc88ef805903d1941ca
ToppCellsevere-gd_T|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MAGEE1 GTF3C1 SYNE1 SYNE2

2.71e-05199394e5a17a9f8f3be05d6abe1116607d17633df3c7ef
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GTF3C1 SYNE1 SYNE2 RPL19

2.71e-0519939400ef3cc5c02639bfb839075ecf5f20026ff81f84
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

RPSA SYNE1 SYNE2 RPL19

2.71e-05199394ee29b65a3c545a9d19c2fbcc0364ee235dd018dc
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPSA SYNE1 SYNE2 RPL19

2.71e-05199394accfdf22a2c9e9b926b8328efdadd24979477edf
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

LAMA3 PLXNB2 MYO9A SYNE2

2.76e-052003942dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellPBMC-Severe-Lymphocyte-T/NK|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

RPSA SYNE1 SYNE2 RPL19

2.76e-0520039473b91cb66c375b44e852404a4a445cf2b9595aee
ToppCellBAL-Mild-Lymphocyte-T/NK|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPSA SYNE1 SYNE2 RPL19

2.76e-0520039487c8a4aed9dcfe895d3963708326067e057473c0
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK|ICU-SEP / Disease, condition lineage and cell class

RPSA SYNE1 SYNE2 RPL19

2.76e-05200394b6df9bf85f564f611010bdabc70f02e2155e62f1
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK-CD8+_Tem|ICU-SEP / Disease, condition lineage and cell class

RPSA SYNE1 SYNE2 RPL19

2.76e-0520039485ff6047613068730b935850b7f6e1e2eedf9c69
ToppCellsevere-CD8+_Tem|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RPSA GTF3C1 SYNE1 SYNE2

2.76e-05200394aaa2cd326dc15dee2fd975ca133359c5826f6a75
ToppCellBAL-Mild-Lymphocyte-T/NK|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

RPSA SYNE1 SYNE2 RPL19

2.76e-05200394a6f2e0cf248cc3aa5ccbc812e43227cd8c962915
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK|COVID-19_Severe / Disease, condition lineage and cell class

RPSA SYNE1 SYNE2 RPL19

2.76e-05200394323cb89add511fbe9896b4df0f1f2b7fdbb6c649
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-MAIT|COVID-19_Mild / Disease, condition lineage and cell class

RPSA GTF3C1 ZSWIM4 SYNE2

2.76e-0520039445b2a84d5a325f551205ae31c164d2de7773d3b6
ToppCellCOVID-19_Severe-Lymphoid_T/NK|COVID-19_Severe / Disease group, lineage and cell class

RPSA SYNE1 SYNE2 RPL19

2.76e-052003949fc818bf5c9133fc2fece47980e71fd3f8603558
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK|Bac-SEP / Disease, condition lineage and cell class

RPSA SYNE1 SYNE2 RPL19

2.76e-05200394b8087202a626e64a49292c0a5f7f7376b7b14a9c
ToppCellPBMC-Severe-Lymphocyte-T/NK|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPSA SYNE1 SYNE2 RPL19

2.76e-05200394f1c8780d64b58b6fb84fffbc27f0ad337b1a6e56
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a7.Cbln4_(Neuron.Slc17a7.Cbln4)|Hippocampus / BrainAtlas - Mouse McCarroll V32

FSCN2 CCDC200 TMEM236

4.55e-0579393397f3a1f5fa67dd0b2ed53ebcad74dedf0498fce
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a7.Cbln4_(Neuron.Slc17a7.Cbln4)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

FSCN2 CCDC200 TMEM236

4.55e-0579393d24301b6694f64e8bb1b5f0673f653d25d45d3eb
ToppCellNS-control-d_0-4-Epithelial-IRC-IFNG_responsive_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RPSA SERPINB3 RPL19

6.07e-0587393ed7af0760db6e7871347e422874e25d25a96dc25
ToppCellcontrol-Epithelial-IRC-IFNG_responsive_cell|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RPSA SERPINB3 RPL19

7.64e-05943935653aa476889ac2820d21153acecaadb7cc35ae4
ToppCellNS-control-d_0-4-Epithelial-Basal|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RPSA SERPINB3 RPL19

8.14e-0596393163268827cac146e57ea89e2d56c82aa1af4915e
ToppCellcontrol-Epithelial-Basal|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RPSA SERPINB3 RPL19

1.22e-04110393192e056e4a75317dfa978997081485a9d9744a09
ToppCellcontrol-Epithelial-IRC-IFNG_responsive_cell|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RPSA SERPINB3 RPL19

1.25e-041113930897afc73ebf736f60458b65f66f9ca4284eb918
ToppCellcontrol-Epithelial-Basal|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RPSA SERPINB3 RPL19

1.35e-04114393276e32c2e04c4c060078cd5277ac5a9ae02033f8
ToppCellControl-Epithelial_alveolar-Mes-Like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA3 DNAH10 A3GALT2

1.43e-04116393df7609503782d8d7e4f31ed2a626916e5474d5bc
ToppCellsevere_influenza-B_cell|severe_influenza / disease group, cell group and cell class (v2)

PLXNA3 MGAT5 ZSWIM4

1.91e-0412839392b250186d6bb08ce4f2f5cc4fb93928f6b92d3a
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CATIP ANKMY1 A3GALT2

2.59e-041423935690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDC20B ANKMY1 DNAH10

3.10e-04151393633ed52dd3b4cf1e87432cf0a1ca187d7b204e83
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDC20B ANKMY1 DNAH10

3.10e-04151393e335dad89e0a44cdd302b9653154ba5d1ee5fe1a
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PCDH10 SYNE1 TMEM236

3.22e-04153393764fb5e5fa028c137b8ea65dcd5e4ec9b22191e9
ToppCellsevere_COVID-19-MAIT|World / disease group, cell group and cell class (v2)

MSANTD1 ANKMY1 GTF3C1

3.28e-0415439365ec7f7ef05c589903c4c9fe3849478c325fdc61
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CATIP ANKMY1 DNAH10

3.28e-041543937556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CATIP ANKMY1 DNAH10

3.28e-041543934e3bc24043144143842627cacf6f90dda2228910
ToppCellcritical-Epithelial-Basal|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RPSA SERPINB3 RPL19

3.35e-04155393cb6fbd36aa1fab29a1667ee13441bddc3d28846f
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDC20B SERPINB3 PTK2

3.47e-04157393c43f2e1ea53b375a7432f17f87cfef3b2261003d
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDC20B PLXNB2 SERPINB3

3.60e-0415939360b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCellNS-critical-d_07-13-Epithelial-Basal|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RPSA SERPINB3 RPL19

3.67e-04160393f538ce75500773b5dda53fec4cde2f557d816f4e
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSANTD1 PLXNB2 SYNE1

3.74e-041613933f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA3 MEST RIMS2

3.81e-04162393373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RIMS2 MYO9A SYNE2

3.95e-041643931cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellLeuk-UTI-Lymphocyte-T_NK-CD4_TEM|Leuk-UTI / Disease, Lineage and Cell Type

RPSA SYNE1 SYNE2

4.02e-0416539308285c09de16ed4f488abb655a22f54bc07968ae
ToppCellfacs-Heart-RA-24m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E RPSA HAMP

4.02e-04165393995f1524965a4314938f27165166f0aaff9dea02
ToppCellIIF-Lymphocyte-T_NK-Treg|IIF / Disease, Lineage and Cell Type

RPSA SYNE2 RPL19

4.31e-04169393aac6ff89e0b3bc1f644e6cc6a696360659b254b5
ToppCell356C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PPIG GNPTG SERPINB3

4.31e-041693930425d2580ed325178f522c0093ff4623de6ce7a8
ToppCell356C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PPIG GNPTG SERPINB3

4.31e-04169393fec669968a77060bd77ee8695034e35a642c984f
ToppCellsevere_influenza-gd_T|World / disease group, cell group and cell class (v2)

GTF3C1 SYNE1 SYNE2

4.31e-041693936d514dd2d1e5253bce49279f43aa2fa2b7c2653e
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Deuterosomal|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CDC20B CATIP DNAH10

4.46e-0417139352aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Deuterosomal|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CDC20B CATIP DNAH10

4.53e-0417239308ad76412c9cc3504141797b44b88478ced87476
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-NK_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MGAT5 PCDH10 WDR59

4.53e-04172393a126dacd94939851de1403d30f0b63eaad48bfa1
ToppCellmild_COVID-19_(asymptomatic)-gd_T|World / disease group, cell group and cell class (v2)

GTF3C1 SYNE1 SYNE2

4.61e-04173393b6615ff02f5017d7150b1e33b53f8c7a26081a0d
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPSA RIMS2 DNAH10

4.61e-0417339366f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPSA RIMS2 DNAH10

4.61e-04173393649b08a409095592cccf31883be69c754411280d
ToppCellIIF-Lymphocyte-T_NK-CD4_TEM|IIF / Disease, Lineage and Cell Type

RPSA SYNE2 RPL19

4.77e-041753930e7cde3bd638ab85abe915d40c432123f92af4fc
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GTF3C1 SYNE1 SYNE2

4.77e-04175393cc2428150987911d0d382e8177918724aa69f85c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LAMA3 SYNE1 SYNE2

4.85e-041763935914e7635474e7cf24d446bdb1423bc0807ee9c6
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RPSA MAGEE1 RPL19

4.85e-0417639337a73c1980db2a2b2da67742bf05f6a5cf936bbe
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-RGCs_early_1|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

MEST RPSA RPL19

4.85e-041763932a15437c5f5dbf6398d5ea70050632c24a7dc66c
ToppCellControl-Lymphocyte-T_NK-CD8_TCM|Control / Disease, Lineage and Cell Type

RPSA SYNE2 RPL19

4.85e-041763931a7948eb86ee1da607db4d0576312b2859d94523
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GTF3C1 SYNE1 SYNE2

4.85e-04176393003076f1a983409ddf31b9c19e61c1facdd72566
ToppCellIIF-Lymphocyte-T_NK-MAIT|IIF / Disease, Lineage and Cell Type

RPSA GTF3C1 SYNE2

5.01e-04178393be777ebef8f09a1a16fcee8fc69a65ab295b6e1d
ToppCellControl-Lymphocyte-T_NK-CD4_CTL|Control / Disease, Lineage and Cell Type

GTF3C1 SYNE1 SYNE2

5.01e-0417839332fbb7a8d7daa7cb37f42923514acbb9090e6811
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDC20B CACNA1E RIMS2

5.09e-04179393d15182c668d7c37be8214cad9f1fe35d1409c9a1
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDC20B CACNA1E RIMS2

5.09e-04179393e22a275a7c0ed19113c833a75d6c49fcc19aa13a
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA3 PLXNB2 SYNE2

5.09e-04179393fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellcritical-Epithelial-Basal|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RPSA SERPINB3 RPL19

5.18e-04180393af6251d550b8a80c104bcbb104478b314a45366e
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPSA GTF3C1 SYNE2

5.35e-04182393f30e5a21b49f30b82e2b6f1fd2daefd805a40083
ToppCellCOVID-19_Severe-Lymphoid_T/NK-MAIT|COVID-19_Severe / Disease group, lineage and cell class

RPSA GTF3C1 SYNE2

5.35e-0418239319045db5c726c06ec6e4feb4311633c8164ddb3c
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPSA GTF3C1 SYNE2

5.35e-041823931444cdc4522a70a40d697ccadf54cf26d327ade0
Diseaselung small cell carcinoma (is_implicated_in)

LAMA3 PBRM1 PTK2

6.83e-0628393DOID:5409 (is_implicated_in)
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE1 SYNE2

1.02e-054392cv:CN293514
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

1.70e-055392C1450051
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE1 SYNE2

1.70e-055392C0410190
DiseaseEmery-Dreifuss muscular dystrophy

SYNE1 SYNE2

2.54e-056392cv:C0410189
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE1 SYNE2

2.54e-056392C0410189
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

3.56e-057392C0751337
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE1 SYNE2

1.11e-0412392DOID:11726 (implicated_via_orthology)
Diseaseunipolar depression, bipolar disorder

CACNA1E SYNE1 SYNE2

1.15e-03156393EFO_0003761, MONDO_0004985
DiseaseParoxysmal atrial fibrillation

DNAH10 PTK2 SYNE2

1.15e-03156393C0235480
DiseasePersistent atrial fibrillation

DNAH10 PTK2 SYNE2

1.15e-03156393C2585653
Diseasefamilial atrial fibrillation

DNAH10 PTK2 SYNE2

1.15e-03156393C3468561
DiseaseAtrial Fibrillation

DNAH10 PTK2 SYNE2

1.24e-03160393C0004238
Diseasehepatocellular carcinoma (implicated_via_orthology)

HAMP PTK2

1.92e-0349392DOID:684 (implicated_via_orthology)
DiseaseMouth Neoplasms

SERPINB3 PTK2

2.33e-0354392C0026640
DiseaseMalignant neoplasm of mouth

SERPINB3 PTK2

2.33e-0354392C0153381

Protein segments in the cluster

PeptideGeneStartEntry
MSMWEPRSSHLRERR

CACNA1E

756

Q15878
WDEAMRRLQERMGRL

ALDH16A1

316

Q8IZ83
RRARNWTDAEMRGLM

MSANTD1

41

Q6ZTZ1
AMRRIWNRLMVVSDE

OR4C15

296

Q8NGM1
TMADALWRLRDLMLR

PBRM1

1661

Q86U86
MLWRMGVQRERRLSI

MAGEE1

606

Q9HCI5
FSREWAEAQRMMREL

LAMA3

1966

Q16787
RWMRLRIRRMADAWI

MGAT5

236

Q09328
AEDMDLEWRQGRMTR

PLXNA3

1526

P51805
RRSETVVERMLSNWM

PLXNB2

1391

O15031
MNLFRMDWRTGELRT

PCDH10

626

Q9P2E7
MQRAQRMRVSSGERW

PPIG

366

Q13427
MRNWMTRQASRESTD

RIMS2

1196

Q9UQ26
DTMRRLMSSRDWPRT

NOTUM

141

Q6P988
MWMRDGDACRSRSRQ

GNPTG

121

Q9UJJ9
RRQMALDRRRWLMAQ

CCDC200

11

A0A1B0GVQ3
ERRWQDVSMARMRTL

A3GALT2

166

U3KPV4
LRVMAWRRMVPSNAR

CATIP

181

Q7Z7H3
MALSMIERRKRWRTI

ANKMY1

516

Q9P2S6
RRVRTEEEMLWESIM

CDC20B

11

Q86Y33
RVEDWMTAVLNEMRR

DNAH10

1636

Q8IVF4
MVRRDRLRRMREWWV

MEST

1

Q5EB52
NTMFEMEWRGRRVAL

FSCN2

331

O14926
WMLAREVLRMRGTIS

RPSA

176

P08865
WRVRVQRRRCEMSTM

TMCO1

41

Q9UM00
LDRRWRNICAMSMER

SYNE1

7976

Q8NF91
RSLDRRWRNICAMSM

SYNE2

6111

Q8WXH0
MRMESRRQATVSWDS

PTK2

691

Q05397
EKVTWMRRMRILRRL

RPL19

91

P84098
AVQMRVWRERMVEPE

SCRIB

806

Q14160
LMEWTSLQNMRETRV

SERPINB3

266

P29508
PSMDRARAWRRMSRS

HTR3D

166

Q70Z44
SRDQTLRMWRVDSQM

WDR59

306

Q6PJI9
LRMWRVDSQMQRLCA

WDR59

311

Q6PJI9
RHSWTKDRRAMRVMS

ZC3H7A

736

Q8IWR0
QRMTRLRVTWSMQED

GTF3C1

1256

Q12789
RMMSRRDVRAELFLW

TMEM236

226

Q5W0B7
TLNVMTWRRREMVRW

ZSWIM4

681

Q9H7M6
RASWMPMFQRRRRRD

HAMP

46

P81172
LQSWLRVTEERRRMM

MYO9A

121

B2RTY4