Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessmitotic cell cycle checkpoint signaling

FANCD2 PLK2 ATR ABRAXAS1 BUB1B MAD2L2

2.44e-05163736GO:0007093
GeneOntologyBiologicalProcessregulation of Wnt signaling pathway

APCDD1 RNF213 MACF1 XIAP MAD2L2 SKI TBL1XR1 TBL1X

4.66e-05368738GO:0030111
GeneOntologyBiologicalProcesscell cycle phase transition

FANCD2 CDKN3 PLK2 ATR ABRAXAS1 BUB1B SMARCD2 MAD2L2 ESPL1 MELK

6.95e-056277310GO:0044770
GeneOntologyBiologicalProcessmitotic cell cycle phase transition

CDKN3 PLK2 ATR ABRAXAS1 BUB1B SMARCD2 MAD2L2 ESPL1 MELK

7.55e-05509739GO:0044772
GeneOntologyBiologicalProcesscell cycle checkpoint signaling

FANCD2 PLK2 ATR ABRAXAS1 BUB1B MAD2L2

1.20e-04217736GO:0000075
MousePhenodecreased skeletal muscle fiber diameter

BUB1B DMD SKI RYR1

2.84e-0542594MP:0009402
DomainSpectrin/alpha-actinin

EVPLL SPTBN2 MACF1 EVPL DMD

1.28e-0732715IPR018159
DomainSPEC

EVPLL SPTBN2 MACF1 EVPL DMD

1.28e-0732715SM00150
DomainSpectrin_repeat

SPTBN2 MACF1 EVPL DMD

4.24e-0629714IPR002017
DomainEnvoplakin

EVPLL EVPL

1.42e-052712IPR030460
DomainActinin_actin-bd_CS

SPTBN2 MACF1 DMD

8.83e-0523713IPR001589
DomainSpectrin

SPTBN2 MACF1 DMD

8.83e-0523713PF00435
DomainACTININ_2

SPTBN2 MACF1 DMD

8.83e-0523713PS00020
DomainACTININ_1

SPTBN2 MACF1 DMD

8.83e-0523713PS00019
DomainCH

MICALL1 SPTBN2 MACF1 DMD

1.09e-0465714SM00033
DomainCH

MICALL1 SPTBN2 MACF1 DMD

1.45e-0470714PF00307
Domain-

MICALL1 SPTBN2 MACF1 DMD

1.54e-04717141.10.418.10
DomainCH

MICALL1 SPTBN2 MACF1 DMD

1.71e-0473714PS50021
DomainCH-domain

MICALL1 SPTBN2 MACF1 DMD

1.90e-0475714IPR001715
DomainRIH_assoc

RYR1 ITPR2

2.12e-046712PF08454
DomainRIH_assoc-dom

RYR1 ITPR2

2.12e-046712IPR013662
Domain-

MACF1 EVPL

2.12e-0467123.90.1290.10
DomainRIH_dom

RYR1 ITPR2

2.12e-046712IPR000699
DomainIns145_P3_rcpt

RYR1 ITPR2

2.12e-046712IPR014821
DomainRyanodine_recept-rel

RYR1 ITPR2

2.12e-046712IPR015925
Domain-

RYR1 ITPR2

2.12e-0467121.25.10.30
DomainRYDR_ITPR

RYR1 ITPR2

2.12e-046712PF01365
DomainIns145_P3_rec

RYR1 ITPR2

2.12e-046712PF08709
Domainzf-C2H2

IKZF2 ZNF451 TRPS1 ZIM2 ZNF749 ZNF679 ZNF471 ZBTB1 ZUP1 IKZF4

2.77e-046937110PF00096
DomainPlectin_repeat

MACF1 EVPL

2.96e-047712IPR001101
DomainPlectin

MACF1 EVPL

2.96e-047712PF00681
DomainPLEC

MACF1 EVPL

2.96e-047712SM00250
DomainLisH

TBL1XR1 TBL1X

5.04e-049712PF08513
DomainMIR

RYR1 ITPR2

6.29e-0410712PS50919
DomainMIR

RYR1 ITPR2

6.29e-0410712PF02815
DomainMIR

RYR1 ITPR2

6.29e-0410712SM00472
DomainMIR_motif

RYR1 ITPR2

6.29e-0410712IPR016093
DomainZINC_FINGER_C2H2_2

IKZF2 ZNF451 TRPS1 ZIM2 ZNF749 ZNF679 ZNF471 ZBTB1 ZUP1 IKZF4

6.67e-047757110PS50157
DomainZINC_FINGER_C2H2_1

IKZF2 ZNF451 TRPS1 ZIM2 ZNF749 ZNF679 ZNF471 ZBTB1 ZUP1 IKZF4

6.80e-047777110PS00028
DomainZnf_C2H2-like

IKZF2 ZNF451 TRPS1 ZIM2 ZNF749 ZNF679 ZNF471 ZBTB1 ZUP1 IKZF4

8.19e-047967110IPR015880
DomainZnf_C2H2

IKZF2 ZNF451 TRPS1 ZIM2 ZNF749 ZNF679 ZNF471 ZBTB1 ZUP1 IKZF4

8.92e-048057110IPR007087
DomainZnF_C2H2

IKZF2 ZNF451 TRPS1 ZIM2 ZNF749 ZNF679 ZNF471 ZBTB1 ZUP1 IKZF4

9.18e-048087110SM00355
Domain6-hairpin_glycosidase-like

PHKA2 AGL

1.08e-0313712IPR008928
DomainLisH

TBL1XR1 TBL1X

5.05e-0328712SM00667
DomainLisH

TBL1XR1 TBL1X

5.05e-0328712IPR006594
DomainLISH

TBL1XR1 TBL1X

5.05e-0328712PS50896
PathwayKEGG_MEDICUS_REFERENCE_SPINDLE_ASSEMBLY_CHECKPOINT_SIGNALING

BUB1B MAD2L2 ESPL1

6.01e-0521523M47583
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MIER2 CTTNBP2 GBF1 MAN2B2 SS18L1 SPTBN2 CEP135 RNF213 MACF1

1.18e-0649375915368895
Pubmed

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.

MIER2 CDYL TBL1XR1 TBL1X

2.78e-064575421258344
Pubmed

TBL1X: At the crossroads of transcriptional and posttranscriptional regulation.

TBL1XR1 TBL1X

4.59e-06275236206873
Pubmed

SUMOylation of TBL1 and TBLR1 promotes androgen-independent prostate cancer cell growth.

TBL1XR1 TBL1X

4.59e-06275227129164
Pubmed

ATR couples FANCD2 monoubiquitination to the DNA-damage response.

FANCD2 ATR

4.59e-06275215314022
Pubmed

BUB1B Promotes Proliferation of Prostate Cancer via Transcriptional Regulation of MELK.

BUB1B MELK

4.59e-06275231893996
Pubmed

CD4+ regulatory T cells lacking Helios and Eos.

IKZF2 IKZF4

4.59e-06275237413709
Pubmed

Primary Autosomal Recessive Microcephalies and Seckel Syndrome Spectrum Disorders – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

ATR CEP135 NIN

5.29e-061675320301772
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

FANCD2 ATR ABRAXAS1 ZNF451 SS18L1 SMARCD2 MAD2L2 ZBTB1

6.13e-0645375829656893
Pubmed

PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle.

PLK2 CEP135

1.37e-05375220531387
Pubmed

Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance.

FANCD2 ATR

1.37e-05375216943440
Pubmed

Regulation of the Fanconi Anemia DNA Repair Pathway by Phosphorylation and Monoubiquitination.

FANCD2 ATR

1.37e-05375234828369
Pubmed

Differential roles for Chk1 and FANCD2 in ATR-mediated signalling for psoralen photoactivation-induced senescence.

FANCD2 ATR

1.37e-05375221995812
Pubmed

Type 1 inositol (1,4,5)-trisphosphate receptor activates ryanodine receptor 1 to mediate calcium spark signaling in adult mammalian skeletal muscle.

RYR1 ITPR2

1.37e-05375223223241
Pubmed

Remodeling of Interstrand Crosslink Proximal Replisomes Is Dependent on ATR, FANCM, and FANCD2.

FANCD2 ATR

1.37e-05375231067464
Pubmed

Syndrome disintegration: Exome sequencing reveals that Fitzsimmons syndrome is a co-occurrence of multiple events.

TRPS1 TBL1XR1

1.37e-05375227133561
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

MAN2B2 TTC21A SDCCAG8 TRPS1 SEL1L3 RNF213 MACF1 XIAP CAMKMT SKI TBL1XR1 TASOR2 TBL1X

1.64e-051489751328611215
Pubmed

Structural studies on a protein-binding zinc-finger domain of Eos reveal both similarities and differences to classical zinc fingers.

TRPS1 IKZF4

2.75e-05475215491138
Pubmed

The Ikaros family protein Eos associates with C-terminal-binding protein corepressors.

TRPS1 IKZF4

2.75e-05475212444977
Pubmed

TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis.

TBL1XR1 TBL1X

2.75e-05475218193033
Pubmed

Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle.

DMD RYR1

2.75e-05475219198614
Pubmed

TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints.

TBL1XR1 TBL1X

2.75e-05475218374649
Pubmed

STIM1 signalling controls store-operated calcium entry required for development and contractile function in skeletal muscle.

DMD RYR1

2.75e-05475218488020
Pubmed

Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.

MACF1 DMD

2.75e-0547528954775
Pubmed

The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-FANCD2 pathways.

FANCD2 ATR

2.75e-05475214988723
Pubmed

A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells.

IKZF2 IKZF4

2.75e-05475222961053
Pubmed

Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.

RYR1 ITPR2

2.75e-05475219120137
Pubmed

Loss of β2-spectrin prevents cardiomyocyte differentiation and heart development.

SPTBN2 DMD

2.75e-05475224064296
Pubmed

FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.

FANCD2 ATR

2.75e-05475218931676
Pubmed

iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated dystrophin.

DMD RYR1

2.75e-05475232693782
Pubmed

Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia.

TBL1XR1 TBL1X

4.57e-05575221459324
Pubmed

A screen for MeCP2-TBL1 interaction inhibitors using a luminescence-based assay.

TBL1XR1 TBL1X

4.57e-05575236890145
Pubmed

Function of multiple Lis-Homology domain/WD-40 repeat-containing proteins in feed-forward transcriptional repression by silencing mediator for retinoic and thyroid receptor/nuclear receptor corepressor complexes.

TBL1XR1 TBL1X

4.57e-05575218202150
Pubmed

The mammalian LINC complex component SUN1 regulates muscle regeneration by modulating drosha activity.

RTL1 DMD

4.57e-05575231686651
Pubmed

Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities.

IKZF2 IKZF4

4.57e-05575210978333
Pubmed

SENP2 regulates MMP13 expression in a bladder cancer cell line through SUMOylation of TBL1/TBLR1.

TBL1XR1 TBL1X

4.57e-05575226369384
Pubmed

Histone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore-microtubule attachment.

TBL1XR1 TBL1X

4.57e-05575218326024
Pubmed

Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders.

TBL1XR1 TBL1X

6.84e-05675228348241
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR1 ITPR2

6.84e-05675223463619
Pubmed

Functional interaction between BubR1 and securin in an anaphase-promoting complex/cyclosomeCdc20-independent manner.

BUB1B ESPL1

6.84e-05675219117984
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR1 ITPR2

6.84e-05675220519450
Pubmed

ATR-ATRIP kinase complex triggers activation of the Fanconi anemia DNA repair pathway.

FANCD2 ATR

6.84e-05675222258451
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR1 ITPR2

6.84e-05675225966694
Pubmed

Genetic variation in the major mitotic checkpoint genes does not affect familial breast cancer risk.

BUB1B MAD2L2

6.84e-05675217268814
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR1 ITPR2

6.84e-05675216844763
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

TRPC7 RYR1 ITPR2

7.70e-053875330786075
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

GBF1 ABRAXAS1 ZNF451 RNF213 MACF1 XIAP ZUP1

8.17e-0548175728190767
Pubmed

Nox4 - RyR1 - Nox2: Regulators of micro-domain signaling in skeletal muscle.

DMD RYR1

9.57e-05775232506037
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR1 ITPR2

9.57e-05775211860456
Pubmed

Zbtb7c is a molecular 'off' and 'on' switch of Mmp gene transcription.

TBL1XR1 TBL1X

9.57e-05775227646874
Pubmed

The nuclear receptor corepressor deacetylase activating domain is essential for repression by thyroid hormone receptor.

TBL1XR1 TBL1X

9.57e-05775215695367
Pubmed

Interaction network of human early embryonic transcription factors.

SS18L1 TRPS1 SMARCD2 SKI TBL1XR1 TBL1X

1.13e-0435175638297188
Pubmed

Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development.

SS18L1 BUB1B

1.27e-04875235905187
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR1 ITPR2

1.27e-04875219033399
Pubmed

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor.

TBL1XR1 TBL1X

1.27e-04875223770565
Pubmed

sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1.

SS18L1 NIN

1.27e-04875218331714
Pubmed

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma.

TBL1XR1 TBL1X

1.27e-04875216127449
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

FANCD2 DSC2 SS18L1 TRPS1 RNF213 MACF1 XIAP SMARCD2 SKI NIN

1.39e-041116751031753913
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

IKZF2 TRPS1 MACF1 XIAP SMARCD2 ZBTB1 IKZF4 LIMS2

1.45e-0470975822988430
Pubmed

Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.

ZNF451 TRPS1 MAD2L2 ZBTB1

1.59e-0412575432891193
Pubmed

Reading and function of a histone code involved in targeting corepressor complexes for repression.

TBL1XR1 TBL1X

1.64e-04975215601853
Pubmed

BRCA1-mediated chromatin silencing is limited to oocytes with a small number of asynapsed chromosomes.

ATR SS18L1

1.64e-04975219531582
Pubmed

Hurp deficiency in mice leads to female infertility caused by an implantation defect.

BUB1B MAD2L2

1.64e-04975218676373
Pubmed

Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos.

IKZF2 IKZF4

1.64e-04975222638570
Pubmed

Characterization of MAD2B and other mitotic spindle checkpoint genes.

BUB1B MAD2L2

1.64e-04975210366450
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

PHKA2 PLK2 ZNF451 TRPS1 BUB1B CEP135 SMARCD2 MAD2L2 ESPL1 TASOR2

1.84e-041155751020360068
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

AGL TTC21A SPTBN2 INTS1 RNF213 EVPL RYR1 ITPR2

1.87e-0473675829676528
Pubmed

Ski co-repressor complexes maintain the basal repressed state of the TGF-beta target gene, SMAD7, via HDAC3 and PRMT5.

SKI TBL1XR1

2.04e-041075219032343
Pubmed

AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis.

DMD RYR1

2.04e-041075218434328
Pubmed

A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors.

TBL1XR1 TBL1X

2.04e-041075214980219
Pubmed

The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2.

TBL1XR1 TBL1X

2.04e-041075211931768
Pubmed

Cdk12 is essential for embryonic development and the maintenance of genomic stability.

FANCD2 ATR

2.04e-041075226658019
Pubmed

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

MIER2 IKZF2 SS18L1 RAPGEF4 ZBTB1 TASOR2

2.36e-0440275624722188
Pubmed

ROS/NF-κB Signaling Pathway-Mediated Transcriptional Activation of TRIM37 Promotes HBV-Associated Hepatic Fibrosis.

XIAP SKI

2.49e-041175232916597
Pubmed

Functional proteomics mapping of a human signaling pathway.

PHKA2 ZNF451 CEP135 MACF1 SKI AKR1B1 LIMS2

2.89e-0459175715231748
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

TRPS1 SMARCD2 SKI TBL1XR1 TBL1X

2.91e-0426875533640491
Pubmed

HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis.

FANCD2 ATR

2.99e-041275224005329
Pubmed

The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-β signaling.

TRPS1 SKI

2.99e-041275223537899
Pubmed

miR-30 family microRNAs regulate myogenic differentiation and provide negative feedback on the microRNA pathway.

SMARCD2 DMD

2.99e-041275225689854
Pubmed

Conservation and reorganization of loci on the mammalian X chromosome: a molecular framework for the identification of homologous subchromosomal regions in man and mouse.

PHKA2 DMD

2.99e-04127522899541
Pubmed

Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.

ATR BUB1B ESPL1

3.17e-046175327694478
Pubmed

SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.

FANCD2 INTS1 MAD2L2 ITPR2

3.18e-0415075430154076
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

FANCD2 ATR ZNF451 TRPS1 INTS1 RNF213 SMARCD2 AKR1B1 TBL1XR1

3.29e-04101475932416067
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

MIER2 ABRAXAS1 ZNF451 INTS1 SMARCD2 CDYL TBL1XR1

3.42e-0460875736089195
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

MIER2 IKZF2 ZNF451 TRPS1 SMARCD2 ZNF679 ZUP1 LIMS2

3.51e-0480875820412781
Pubmed

N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso.

TBL1XR1 TBL1X

3.52e-041375214527417
Pubmed

Ikaros confers early temporal competence to mouse retinal progenitor cells.

IKZF2 IKZF4

3.52e-041375218940586
Pubmed

Meiotic failure in male mice lacking an X-linked factor.

ATR SS18L1

3.52e-041375218316482
Pubmed

MASTL promotes cyclin B1 destruction by enforcing Cdc20-independent binding of cyclin B1 to the APC/C.

BUB1B ESPL1

3.52e-041375225750436
Pubmed

Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development.

MOXD1 SS18L1 SMARCD2

3.82e-046575326655900
Pubmed

A molecular dissection of the repression circuitry of Ikaros.

IKZF2 IKZF4

4.11e-041475212015313
Pubmed

USP44 Is an Integral Component of N-CoR that Contributes to Gene Repression by Deubiquitinating Histone H2B.

TBL1XR1 TBL1X

4.11e-041475227880911
Pubmed

Mapping of a liver phosphorylase kinase alpha-subunit gene on the mouse X chromosome.

PHKA2 DMD

4.11e-04147528432533
Pubmed

The functional interactome landscape of the human histone deacetylase family.

MIER2 IKZF2 CDYL TBL1XR1 TBL1X

4.11e-0428975523752268
Pubmed

Gene expression and cell identity controlled by anaphase-promoting complex.

BUB1B TBL1XR1 TBL1X

4.36e-046875332076268
Pubmed

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.

MIER2 CDYL DMD TBL1XR1 TBL1X

4.72e-0429875530737378
Pubmed

The Fanconi anemia family of genes and its correlation with breast cancer susceptibility and breast cancer features.

FANCD2 ATR

4.73e-041575219536649
Pubmed

Cdk12 Regulates Neurogenesis and Late-Arising Neuronal Migration in the Developing Cerebral Cortex.

FANCD2 ATR

4.73e-041575227073218
Pubmed

Phosphorylation of thyroid hormone receptor-associated nuclear receptor corepressor holocomplex by the DNA-dependent protein kinase enhances its histone deacetylase activity.

TBL1XR1 TBL1X

4.73e-041575217242407
Pubmed

Functional screening of FxxLF-like peptide motifs identifies SMARCD1/BAF60a as an androgen receptor cofactor that modulates TMPRSS2 expression.

NLRP10 ZBTB1

4.73e-041575219762545
GeneFamilyEF-hand domain containing|Plakins

EVPLL MACF1 EVPL

1.10e-068503939
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

IKZF2 ZNF451 TRPS1 ZIM2 ZNF749 ZNF679 ZNF471 ZBTB1 ZUP1 IKZF4

2.23e-05718501028
CoexpressionGSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_UP

IFIH1 CDKN3 PLK2 IKZF2 TRPS1 BUB1B LAG3

6.73e-07176747M2981
CoexpressionNAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP

CDKN3 TRPS1 ESPL1 MELK TBL1X

5.40e-0689745M2761
CoexpressionGSE13547_2H_VS_12_H_ANTI_IGM_STIM_ZFX_KO_BCELL_UP

IFIH1 IKZF2 AGL TRPS1 ZUP1 ITPR2

7.91e-06167746M2995
CoexpressionFUJII_YBX1_TARGETS_DN

FANCD2 CDKN3 BUB1B MAD2L2 MELK TBL1X

1.86e-05194746M14340
CoexpressionGSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_DN

PHKA2 NLRP10 BUB1B DOCK10 MPEG1 XIAP

2.20e-05200746M7174
CoexpressionZHONG_PFC_C1_OPC

FANCD2 CDKN3 BUB1B CEP135 ESPL1 MELK

5.82e-05238746M39096
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

TRANK1 ATR TRPS1 LAG3 SEL1L3 DOCK10 RNF213 MACF1 XIAP SKI TBL1XR1 ZBTB1 ITPR2 NIN

6.44e-0514927414M40023
CoexpressionFAN_EMBRYONIC_CTX_MICROGLIA_1

FANCD2 CDKN3 BUB1B ESPL1 MELK

7.86e-05155745M39041
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

IFIH1 MOXD1 CTTNBP2 ATR BUB1B DOCK10 TASOR2 ITPR2 NIN

9.46e-05656749M18979
CoexpressionGSE13547_WT_VS_ZFX_KO_BCELL_UP

IFIH1 IKZF2 TRPS1 CDYL ITPR2

9.97e-05163745M2997
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

GBF1 ATR ZNF451 BUB1B CEP135 MACF1 CDYL DMD MELK TBL1X

1.42e-048567410M4500
CoexpressionGSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_UP

IFIH1 CDKN3 IKZF2 LAG3 RNF213

1.71e-04183745M2993
CoexpressionFLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_DN

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.04e-04190745M761
CoexpressionGSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_DN

FANCD2 CTTNBP2 MELK RYR1 TBL1X

2.19e-04193745M9712
CoexpressionGSE2405_0H_VS_3H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN

APCDD1 DOCK10 ANKRD30B C1R EVPL

2.47e-04198745M6213
CoexpressionGSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_DN

CDKN3 BUB1B ESPL1 AKR1B1 MELK

2.53e-04199745M9422
CoexpressionGSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_UP

CDKN3 BUB1B ESPL1 AKR1B1 MELK

2.53e-04199745M9419
CoexpressionGSE369_SOCS3_KO_VS_IFNG_KO_LIVER_DN

CDKN3 NLRP10 MPEG1 CAMKMT ZUP1

2.53e-04199745M5983
CoexpressionGSE2405_0H_VS_12H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN

APCDD1 INTS1 BUB1B MELK ABCA9

2.53e-04199745M6203
CoexpressionGSE40274_FOXP3_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

IFIH1 RNF213 SKI ZUP1 IKZF4

2.53e-04199745M9180
CoexpressionGSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_UP

IKZF2 BUB1B ESPL1 MELK TBL1X

2.59e-04200745M5041
CoexpressionGSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP

CDKN3 SPTBN2 INTS1 ESPL1 TBL1XR1

2.59e-04200745M7256
CoexpressionGSE17721_0.5H_VS_12H_GARDIQUIMOD_BMDC_UP

PHKA2 GBF1 APCDD1 BUB1B TBL1XR1

2.59e-04200745M4135
CoexpressionGSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP

CDKN3 SDCCAG8 LAG3 MPEG1 MELK

2.59e-04200745M6057
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_1000

MICALL1 FANCD2 DSC2 TRPS1 RAPGEF4 DOCK10 XIAP TBL1XR1 ZBTB1 ABCA9 IKZF4 TASOR2

2.30e-058267312DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#1_top-relative-expression-ranked_1000

FANCD2 TRPS1 RAPGEF4 DOCK10 TBL1XR1 ZBTB1 IKZF4 TASOR2

2.61e-05349738DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k1_1000
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 TRPS1 DOCK10 MPEG1 MACF1 ABCA9 NIN

2.48e-08182757f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 TRPS1 DOCK10 MPEG1 MACF1 ABCA9 NIN

2.78e-081857577adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

FANCD2 CDKN3 MOXD1 APCDD1 BUB1B ESPL1 MELK

4.13e-081967575905f0e3061a6b98b7a33d64c782c3dda2cd51ef
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FANCD2 CDKN3 BUB1B CEP135 MPEG1 ZNF471

4.47e-0717175641932c9e70829ee3d55ca5fdb74d290fc8229416
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDKN3 BUB1B DOCK10 ESPL1 MELK RYR1

7.55e-0718775673931a5ea73799095daff100b5f18853c57c74dc
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

IKZF2 TRANK1 LAG3 RNF213 MACF1 ZBTB1

1.02e-06197756836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTTNBP2 DOCK10 MPEG1 RNF213 RYR1 ITPR2

1.02e-0619775610190b877bf46ba2163d203df9dd3b498c66e52f
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_dorsal_progenitors|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

FANCD2 CDKN3 BUB1B CEP135 ESPL1 MELK

1.05e-061987565f0964c3aa7e1dc52cbb46e754078920b65bcb88
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

FANCD2 CDKN3 BUB1B CEP135 ESPL1 MELK

1.05e-06198756629d674a9c9108c1acb3f7af57bbdbf34bb0528e
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_dorsal_progenitors|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

FANCD2 CDKN3 APCDD1 BUB1B ESPL1 MELK

1.05e-06198756dada1c19a261c8e1090957cd7e37f2a43a9fe14f
ToppCellsevere_influenza-T/NK_proliferative|severe_influenza / disease group, cell group and cell class (v2)

FANCD2 CDKN3 BUB1B LAG3 ESPL1 MELK

1.08e-06199756638b1491c47f2884daf1c1d38a779ad8e0f59c52
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PLK2 RAPGEF4 RNF213 MACF1 NIN LIMS2

1.12e-06200756dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FANCD2 CDKN3 BUB1B MAD2L2 MELK ZNF738

1.12e-0620075638665128b54f4a81b53c961427aed67bf4e2510b
ToppCelldroplet-Tongue-nan-24m-Epithelial-suprabasal_interpapillary|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFIH1 PLK2 IKZF2 DSC2 EVPL

1.07e-051727556ece9bb9f31685c918ca4cb7b82cf6ad1cad48af
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_2|343B / Donor, Lineage, Cell class and subclass (all cells)

FANCD2 CDKN3 BUB1B MPEG1 MELK

1.13e-05174755a75ba49ccea6bd3d78ada1092b46deb5202c58a5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.13e-05174755dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDKN3 OTOGL BUB1B MELK RYR1

1.16e-051757559142ed8ca2f1c0c518deb21988221406f62fe38c
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDKN3 BUB1B ZNF471 MELK RYR1

1.16e-0517575573f25bd54309aed1480ddc44bdab518b17e71f92
ToppCellfacs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN3 TTC21A BUB1B ESPL1 MELK

1.23e-051777558a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCellSevere-CD4+_T_activated|Severe / Disease group and Cell class

IFIH1 TRANK1 APCDD1 TTC21A RNF213

1.23e-05177755a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCellfacs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN3 TTC21A BUB1B ESPL1 MELK

1.23e-05177755e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCellSevere-CD4+_T_activated|World / Disease group and Cell class

IFIH1 TRANK1 APCDD1 TTC21A RNF213

1.26e-05178755ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCellDividing_Macrophages-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.26e-051787551893fadac2ec3d5de0a641e57b7b2f962012a9ba
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.33e-051807555e1680088065be14447d5d5465f91f7edd071a1e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.33e-05180755401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.33e-05180755334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.33e-05180755f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCellP28-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.37e-05181755e482fd116c00ff4d8db7be3c06b1bd1ffa2d479d
ToppCellP28-Endothelial-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.37e-051817552be3d44619adb25d339e7a27b500a56e07e8de01
ToppCellmild_COVID-19_(asymptomatic)-T/NK_proliferative|World / disease group, cell group and cell class (v2)

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.41e-051827559adf90bb2808f234d53b89ca0ae07380478204ad
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

IKZF2 LAG3 RNF213 MACF1 ZBTB1

1.44e-05183755f593a89b0aa8fffdfa403769916facfd30358521
ToppCellCOVID-19-kidney-CD-IC-A|kidney / Disease (COVID-19 only), tissue and cell type

CTTNBP2 SPTBN2 SHOC1 DOCK10 ITPR2

1.44e-051837555c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCellmild_COVID-19_(asymptomatic)-T/NK_proliferative|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.44e-05183755df8568751205313d149939ea2683097e3652a60b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.52e-0518575530e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCelldroplet-Spleen-SPLEEN-1m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN3 BUB1B ESPL1 MELK IKZF4

1.52e-05185755736bf89a7a1a840ab6920060f2d98598332065a0
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

GBF1 DOCK10 RNF213 MACF1 ITPR2

1.56e-051867558571956890fc9894d766ba294a28e376b4aba428
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-secretory_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IFIH1 PLK2 CEP135 CDYL LIMS2

1.60e-051877556e5c38425b6b1d4774f8dcea7e146f1eab785c3e
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IFIH1 PLK2 CEP135 CDYL LIMS2

1.60e-0518775543ef900b76f3c38bd8ce9858201124130c743d56
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.60e-051877559351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 TRANK1 C1R DMD ABCA9

1.64e-05188755ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.69e-051897551e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 TRANK1 C1R DMD ABCA9

1.73e-05190755efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDKN3 AGL BUB1B MELK RYR1

1.77e-051917550f9443da0f73d07456142fae08b2dc92a5b7b592
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CDKN3 BUB1B CEP135 ESPL1 MELK

1.77e-051917550ba5b112a82e489f5a21966f78a403a7436ce73b
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.77e-05191755b85a0978dc1e8af4f49423f56dcfd52efce09ed1
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.82e-0519275527723f4e320e49d4a3daafa2d8d3946ff79fab64
ToppCellDividing_Macrophages-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.82e-05192755741bd0c2b0a7ce3fcb1610ce8bdacaf9a803c212
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 APCDD1 C1R DMD ABCA9

1.87e-05193755c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.87e-051937554b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-Cycling_T|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.87e-0519375581e6240cffb094b2aa3684fd0889b6497f47c4f0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 APCDD1 C1R DMD ABCA9

1.87e-051937555b602b1702283184bd3943c2a6f2290b7c37e407
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.87e-05193755444de545117dae8ab24a22880583ac2f0b2d6eac
ToppCell3'_v3-Lung-Myeloid_Mac-Cycling_Myeloid-Mac|Lung / Manually curated celltypes from each tissue

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.91e-05194755a8ae49157ca3f9e8b3f1750a995aee012dc859b6
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.91e-05194755f9070035553bc68106a9e0bdf4b507715a138aba
ToppCell(7)_Epithelial_cells-(7)_Epithelial-J_(AT1-AT2_progenitors)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.91e-051947554d6ae2b25db11a4ae6dadee83be5c8c05b1225c3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 APCDD1 C1R DMD ABCA9

1.96e-05195755cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCellInfluenza_Severe-T/NK_proliferative|World / Disease group and Cell class

CDKN3 BUB1B LAG3 ESPL1 MELK

1.96e-051957556f079c2d7d08110a5e1822ea861b8037eb3f62c9
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FANCD2 CDKN3 BUB1B ESPL1 MELK

1.96e-05195755926eb3fc5d028be936885bea0654a77db3107234
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-keratinocyte|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IKZF2 DSC2 SPTBN2 EVPL ITPR2

1.96e-05195755c54b19e31efe2c9ae690062569da7c0f1120a1d8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 APCDD1 C1R DMD ABCA9

1.96e-05195755783bfa8110161cbd6def50ce849cae676c39c458
ToppCellCOVID-19-lung-Proliferative_fibroblast|lung / Disease (COVID-19 only), tissue and cell type

FANCD2 CDKN3 MOXD1 BUB1B MELK

2.01e-051967552ce8a787f2731faa913d20342d73041d59468f27
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.01e-051967551d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.01e-0519675573f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 APCDD1 C1R DMD ABCA9

2.01e-051967553a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 APCDD1 C1R DMD ABCA9

2.01e-05196755bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCellCOVID-19-lung-Proliferative_fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

FANCD2 CDKN3 MOXD1 BUB1B MELK

2.01e-05196755ca91d5e325875e7444809b80fcbd491d8899ea36
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CDKN3 BUB1B LAG3 ESPL1 MELK

2.06e-051977554b13335a43b9d6abc8e542e72440da7feb82fbe6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 APCDD1 C1R DMD ABCA9

2.06e-0519775509946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCellMild_COVID-19-T/NK-proliferating_T/NK|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.06e-051977555fd52fba2cb6fa67377f873da2ff6ce9c83b0591
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.06e-0519775584ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 APCDD1 C1R DMD ABCA9

2.06e-05197755ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellmLN-B_cell-B_cell_cycling|B_cell / Region, Cell class and subclass

IKZF2 BUB1B DMD MELK LIMS2

2.06e-051977552071526fe46de8359ea118ff78581eb4454aa55a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 APCDD1 C1R DMD ABCA9

2.06e-0519775537f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.06e-05197755d7a9296092153cf66426911fecd810f0c1ef978e
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.06e-05197755dcff23240bb7cb652d7426b29355aa74442ef6fc
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic-lymphocyte-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CDKN3 BUB1B LAG3 ESPL1 MELK

2.06e-0519775521861d8b389fafbdb7c3499684c9b6deee3dbd5e
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.06e-05197755434a5686a103bb766e0d80038413f0e12ea3981a
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.06e-051977558b616cde333bdbc0c591035ad9e4949155866245
ToppCellMild-Lymphoid-T-Proliferating_T|Mild / Condition, Lineage, Cell class and cell subclass

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.06e-05197755794517c70089da109f4c6489fe406c0ba6882b76
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.06e-051977556bddfa199ca812d9e518eaa02c3d4fb67e9f5b16
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.06e-05197755c0a71a9452febda433bc544e4ac0a79c43dcf13e
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.06e-05197755f34b1e34f1f0694564031077172c890b233ce8b7
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic-lymphocyte|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CDKN3 BUB1B LAG3 ESPL1 MELK

2.06e-05197755ffb004c37cdd26cb7cdcd80f769a2eded65416dc
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IKZF2 LAG3 RNF213 MACF1 ZBTB1

2.11e-05198755a1b310274aa9b3d2aa1fe9488d67422bf4ac81d2
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.11e-05198755880f9817f5145f10f29fc05c5866090433532fe2
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IKZF2 LAG3 RNF213 MACF1 ZBTB1

2.11e-0519875576aff381403bc5a8a9cc73eb1e5dbdc0bac7de6c
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IKZF2 LAG3 RNF213 MACF1 ZBTB1

2.11e-05198755a781fd35a7cda8b7760c2e3ddccaac7aac26c979
ToppCellmedial-2-Hematologic-Proliferating_Macrophage|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.11e-0519875564a2bcf5a9ba66a4fe08fbde33f1886c136cde8f
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.11e-05198755428182c71f009906c581e02257e545ea5fb99650
ToppCellmedial-Hematologic-Proliferating_Macrophage-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.11e-05198755fcc14ac3eb5088b9d6cd6af5a34dee5b81c0ece8
ToppCelldistal-1-Hematologic-Proliferating_Macrophage|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.11e-05198755df3f5559ecd1f3cd1fd60e39dbad8741309e83a3
ToppCelldistal-Hematologic-Proliferating_Macrophage-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.11e-051987558afeb1f9bc9d8551482c8fefe4c5f88d9cd13ee2
ToppCelldistal-Hematologic-Proliferating_Macrophage-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.11e-051987552b0716e900bce54ad1825d6dcdaf4ebf31f355c4
ToppCellcycling_basal_cell|World / shred by cell class for turbinate

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.11e-05198755e86c1224f5b0890a50a25257628e90c790aae7cd
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IKZF2 LAG3 RNF213 MACF1 ZBTB1

2.11e-05198755df399674345c45738d765a8354ea8d1484572c34
ToppCellCOVID-19_Mild-Lymphoid_T/NK-gd_T|COVID-19_Mild / Disease group, lineage and cell class

IKZF2 LAG3 RNF213 MACF1 ZBTB1

2.11e-051987556aea5d00c417708f05b6d2dfe5a962d80864f8eb
ToppCellmedial-Hematologic-Proliferating_Macrophage|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.11e-05198755da6963184c32761c896a9b91a5321ad84b583736
ToppCellT_cells-GZMK+GZMB+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CDKN3 BUB1B LAG3 ESPL1 MELK

2.11e-05198755085ba270f9defbf5ef45108c6d870e1d7c428479
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.16e-0519975511c3d9fe811a4619347f47d2b0e94066e3085625
ToppCell15-Airway-Mesenchymal-Mesenchyme_RSPO2+|Airway / Age, Tissue, Lineage and Cell class

FANCD2 CDKN3 BUB1B ESPL1 MELK

2.16e-051997555c8b847b794b3e88722f5b841f2539a27251106c
Diseasesensory system disease (implicated_via_orthology)

TBL1XR1 TBL1X

1.71e-053712DOID:0050155 (implicated_via_orthology)
DiseaseEmbryonal Rhabdomyosarcoma

BUB1B DMD

1.58e-048712C0206656
DiseaseMalignant neoplasm of salivary gland

MIER2 ZIM2 ESPL1

1.76e-0445713C0220636
DiseaseSalivary Gland Neoplasms

MIER2 ZIM2 ESPL1

2.01e-0447713C0036095
Diseasenephronophthisis (implicated_via_orthology)

TTC21A SDCCAG8

2.03e-049712DOID:12712 (implicated_via_orthology)
DiseaseMuscle Weakness

CAMKMT DMD

2.54e-0410712C0151786
Diseasesquamous cell carcinoma

TRPS1 CDYL IKZF4

5.73e-0467713EFO_0000707
DiseaseGlycogen storage disease

PHKA2 AGL

7.58e-0417712cv:C0017919
DiseaseVitiligo

IFIH1 IKZF4

7.58e-0417712C0042900
Diseaseperipheral arterial disease, traffic air pollution measurement

MIER2 TRPS1 MACF1 ITPR2

1.25e-03194714EFO_0004265, EFO_0007908
DiseaseFanconi Anemia

FANCD2 MAD2L2

1.65e-0325712C0015625
DiseaseAcute monocytic leukemia

FANCD2 MAD2L2

1.79e-0326712C0023465
DiseaseAdenoid Cystic Carcinoma

MIER2 ZIM2 ESPL1

1.83e-03100713C0010606
DiseaseGlycogen Storage Disease

PHKA2 AGL

1.93e-0327712C0017919
DiseaseMiller Dieker syndrome

FANCD2 MAD2L2

2.22e-0329712C0265219

Protein segments in the cluster

PeptideGeneStartEntry
CNYNHHLDVVDNLTL

ABRAXAS1

311

Q6UWZ7
HQYINCFTLQDLLQH

BUB1B

836

O60566
AACGVNYIHQQLLEH

ANKRD30B

246

Q9BXX2
QLIHLDYDVNSNAHL

ABCA9

376

Q8IUA7
DDEHLLIQHYCQSLN

DMD

3466

P11532
DIDDHQQVHCPYDQL

C1R

241

P00736
CNQDENHKHAQDYVL

DSC2

841

Q02487
RHIDCAHVYQNENEV

AKR1B1

41

P15121
NYHLCNEISERVVQH

ITPR2

1281

Q14571
LLSQIHEEGYNHLEC

MPEG1

421

Q2M385
HQHICQLYHVLETAN

MELK

66

Q14680
EDEALKHIQNYCHEL

FBXL2

196

Q9UKC9
ERIVNSNGELYHEHC

LIMS2

26

Q7Z4I7
CHPELNQYIQDTLHC

MAD2L2

56

Q9UI95
EYALLCQEHAAVLLH

INTS1

2146

Q8N201
LVDQLSHICLHDYRE

NLRP10

86

Q86W26
LCICQETQLQHVEDY

EVPLL

276

A8MZ36
LCICQETQLQHVEDY

EVPL

321

Q92817
ACQQHVHLVQRYLAD

MICALL1

166

Q8N3F8
YTCHIHLQEQQLNAT

LAG3

331

P18627
LEEHKERCHNYLQNV

IKZF2

211

Q9UKS7
QNEQAHTLETEYIHD

MACF1

2176

Q9UPN3
TCENLENTEGLHHLY

PPP4R3C

181

Q6ZMV5
HAHEIQYHACLIQVF

OR52R1

91

Q8NGF1
EHLTCVNHQLESEKY

CEP135

611

Q66GS9
EIQEHINAHHAYESQ

CEP135

931

Q66GS9
HYLIQEATDENLLCQ

ATR

2621

Q13535
ATHLVELAQVLCYHD

ESPL1

626

Q14674
CHEEQLDHSVQSYIK

DOCK10

936

Q96BY6
EQHLVNCEEYIHDFN

CDYL

96

Q9Y232
ECVELLISYDANINH

CTTNBP2

791

Q8WZ74
IIDECHHTNKEAVYN

IFIH1

441

Q9BYX4
TEADYQLHNVQVICH

APCDD1

141

Q8J025
HDGELLCHRIEQEYQ

MAN2B2

691

Q9Y2E5
QTVRDHLYHLCVQAQ

GBF1

1176

Q92538
NLLDLYQQCGIITHH

CDKN3

91

Q16667
HLLEYFCDQELQHRV

RYR1

1941

P21817
STLEEHKERCHNYLQ

IKZF4

261

Q9H2S9
HLENIHNYFQCLAAE

FANCD2

1026

Q9BXW9
SQDELDHYINHLLQS

PHKA2

656

P46019
HLNRHCEKIYENEDQ

MIER2

211

Q8N344
NIGYAAHCDVIHQEL

OTOGL

671

Q3ZCN5
LQGLQLHQDYCSHKD

PLA2G4D

606

Q86XP0
CIHQNHQESIEFDIV

RTL1

481

A6NKG5
ELFNCVHELELIYHT

RAPGEF4

786

Q8WZA2
RQEACHLHNSYLDLQ

SEL1L3

471

Q68CR1
HHVIEECKQENQYLE

NIN

1381

Q8N4C6
QALSNHEDVIHVYDN

TACO1

281

Q9BSH4
TINDQSQYIHHLEAE

SDCCAG8

121

Q86SQ7
TLEHLNTYLCHDNLS

SHOC1

376

Q5VXU9
LQQINAVCDELHIYC

SKI

136

P12755
DNCVHDLQAHNKEIY

TBL1XR1

381

Q9BZK7
HNQLQDGHEREYINC

SMARCD2

341

Q92925
CIQRHENYDEHISNF

CAMKMT

281

Q7Z624
AQQHCRLHYTDLADL

CLEC20A

36

Q6ZU45
DENHHLIQCILEYQS

SS18L1

26

O75177
CIHDLQAHNKEIYTI

TBL1X

446

O60907
LFHNLCTQQHREDYQ

RNF213

1911

Q63HN8
SLLEHFNTVHCQEQD

TRPS1

706

Q9UHF7
LYRHCQDEHDNEIKI

ZNF451

651

Q9Y4E5
QHKIIHIRENSYQCE

ZNF738

221

Q8NE65
HSKEQLAECHQYLQS

nan

91

Q6ZUT4
LYTCAAEHDLHQKEQ

ZNF749

111

O43361
QEYINNIHLTHSLEE

XIAP

336

P98170
ESLVHHILLYQCSNN

MOXD1

231

Q6UVY6
DNREQQHFLQDCHEL

SPTBN2

1276

O15020
QHQIIHTRENSYQCE

ZNF679

201

Q8IYX0
QLYLLQGHLDLCEQH

TTC21A

931

Q8NDW8
LDEHVLTCTNRHLYQ

ZBTB1

231

Q9Y2K1
QHYQLHSQEKTVECD

ZIM2

511

Q9NZV7
ICTNYHILQEHVDLH

ZUP1

201

Q96AP4
KCIHLENIEESIYNH

ZNF471

166

Q9BX82
FQSANIIELLHYHQC

TASOR2

2346

Q5VWN6
YHDHTKIIICSQNEE

PLK2

626

Q9NYY3
CQERNSESYEQHIHL

TRANK1

2766

O15050
LYVDQHVQDDTLHNV

TRPC7

501

Q9HCX4
HRLINYHQEQAVNCL

AGL

386

P35573