Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	alkylglycerol kinase activity	DGKQ DGKZ	1.44e-04	3	139	2	GO:0047649
GeneOntologyMolecularFunction	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	DPYS CRMP1 DCLRE1A	1.73e-04	16	139	3	GO:0016812
GeneOntologyMolecularFunction	lipid kinase activity	CERK DGKQ DGKZ PI4KB	1.86e-04	41	139	4	GO:0001727
Domain	IPT	PKHD1L1 PLXNC1 PKHD1 PLXNA2	4.14e-05	27	136	4	SM00429
Domain	TIG	PKHD1L1 PLXNC1 PKHD1 PLXNA2	7.27e-05	31	136	4	PF01833
Domain	IPT	PKHD1L1 PLXNC1 PKHD1 PLXNA2	8.26e-05	32	136	4	IPR002909
Domain	DAGKc	CERK DGKQ DGKZ	1.30e-04	14	136	3	SM00046
Domain	Rhs_assc_core	TENM4 TENM3	1.57e-04	3	136	2	IPR022385
Domain	Diacylglycerol_kinase_cat_dom	CERK DGKQ DGKZ	1.61e-04	15	136	3	IPR001206
Domain	DAGK	CERK DGKQ DGKZ	1.61e-04	15	136	3	PS50146
Domain	DAGK_cat	CERK DGKQ DGKZ	1.61e-04	15	136	3	PF00781
Domain	NAD/diacylglycerol_kinase	CERK DGKQ DGKZ	2.38e-04	17	136	3	IPR016064
Domain	Tox-GHH_dom	TENM4 TENM3	3.13e-04	4	136	2	IPR028916
Domain	G8_domain	PKHD1L1 PKHD1	3.13e-04	4	136	2	IPR019316
Domain	G8	PKHD1L1 PKHD1	3.13e-04	4	136	2	PS51484
Domain	Tox-GHH	TENM4 TENM3	3.13e-04	4	136	2	PF15636
Domain	G8	PKHD1L1 PKHD1	3.13e-04	4	136	2	SM01225
Domain	Ten_N	TENM4 TENM3	3.13e-04	4	136	2	IPR009471
Domain	Ten_N	TENM4 TENM3	3.13e-04	4	136	2	PF06484
Domain	G8	PKHD1L1 PKHD1	3.13e-04	4	136	2	PF10162
Domain	TENEURIN_N	TENM4 TENM3	3.13e-04	4	136	2	PS51361
Domain	Biotin_BS	ACACA PCCA	5.19e-04	5	136	2	IPR001882
Domain	Biotin_COase_C	ACACA PCCA	5.19e-04	5	136	2	IPR005482
Domain	YD	TENM4 TENM3	5.19e-04	5	136	2	IPR006530
Domain	BC	ACACA PCCA	5.19e-04	5	136	2	PS50979
Domain	Biotin_carb_C	ACACA PCCA	5.19e-04	5	136	2	SM00878
Domain	Biotin_carb_C	ACACA PCCA	5.19e-04	5	136	2	PF02785
Domain	Biotin_carboxylation_dom	ACACA PCCA	5.19e-04	5	136	2	IPR011764
Domain	CPSASE_1	ACACA PCCA	5.19e-04	5	136	2	PS00866
Domain	BIOTIN	ACACA PCCA	5.19e-04	5	136	2	PS00188
Domain	Znf_FYVE_PHD	TCF20 PHF20 KDM5A ZFYVE9 PRDM14 DNMT3A	7.29e-04	147	136	6	IPR011011
Domain	PbH1	PKHD1L1 PKHD1	7.75e-04	6	136	2	SM00710
Domain	Rudment_hybrid_motif	ACACA PCCA	7.75e-04	6	136	2	IPR011054
Domain	Hydantoinase/dihydroPyrase	DPYS CRMP1	7.75e-04	6	136	2	IPR011778
Domain	CPSASE_2	ACACA PCCA	7.75e-04	6	136	2	PS00867
Domain	PbH1	PKHD1L1 PKHD1	7.75e-04	6	136	2	IPR006626
Domain	CbamoylP_synth_lsu-like_ATP-bd	ACACA PCCA	1.08e-03	7	136	2	IPR005479
Domain	BC-like_N	ACACA PCCA	1.08e-03	7	136	2	IPR005481
Domain	CPSase_L_D2	ACACA PCCA	1.08e-03	7	136	2	PF02786
Domain	Biotin_carb_N	ACACA PCCA	1.08e-03	7	136	2	PF00289
Domain	Pectin_lyase_fold/virulence	PKHD1L1 PKHD1	1.43e-03	8	136	2	IPR011050
Domain	-	DPYS CRMP1	1.43e-03	8	136	2	2.30.40.10
Domain	Plexin_cytopl	PLXNC1 PLXNA2	1.83e-03	9	136	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNC1 PLXNA2	1.83e-03	9	136	2	IPR013548
Domain	Plexin	PLXNC1 PLXNA2	1.83e-03	9	136	2	IPR031148
Domain	Biotin_lipoyl	ACACA PCCA	1.83e-03	9	136	2	PF00364
Domain	DAGK_acc	DGKQ DGKZ	2.28e-03	10	136	2	PF00609
Domain	Diacylglycerol_kin_accessory	DGKQ DGKZ	2.28e-03	10	136	2	IPR000756
Domain	Amidohydro_1	DPYS CRMP1	2.28e-03	10	136	2	PF01979
Domain	BIOTINYL_LIPOYL	ACACA PCCA	2.28e-03	10	136	2	PS50968
Domain	Metal-dep_hydrolase_composite	DPYS CRMP1	2.28e-03	10	136	2	IPR011059
Domain	Biotin_lipoyl	ACACA PCCA	2.28e-03	10	136	2	IPR000089
Domain	DAGKa	DGKQ DGKZ	2.28e-03	10	136	2	SM00045
Domain	Amidohydro-rel	DPYS CRMP1	2.77e-03	11	136	2	IPR006680
Domain	-	KIF21B CFAP251 DDB1 ARHGEF10L PLXNC1 WDR90 LRBA PLXNA2	3.07e-03	333	136	8	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	KIF21B CFAP251 DDB1 ARHGEF10L PLXNC1 WDR90 LRBA PLXNA2	3.18e-03	335	136	8	IPR015943
Domain	Single_hybrid_motif	ACACA PCCA	3.31e-03	12	136	2	IPR011053
Domain	ZU5	MACC1 UNC5D	3.31e-03	12	136	2	PF00791
Domain	ZU5_dom	MACC1 UNC5D	3.31e-03	12	136	2	IPR000906
Domain	-	ACACA PCCA	3.90e-03	13	136	2	3.40.50.20
Domain	NHL	TENM4 TENM3	3.90e-03	13	136	2	PS51125
Domain	ATP_GRASP	ACACA PCCA	4.52e-03	14	136	2	PS50975
Domain	ATP-grasp	ACACA PCCA	4.52e-03	14	136	2	IPR011761
Domain	PreATP-grasp_dom	ACACA PCCA	4.52e-03	14	136	2	IPR016185
Domain	PI3/4_kinase_CS	PI4KB PRKDC	5.19e-03	15	136	2	IPR018936
Domain	-	ACACA PCCA	5.19e-03	15	136	2	3.30.1490.20
Domain	-	PI4KB PRKDC	5.91e-03	16	136	2	1.10.1070.11
Domain	PI3Kc	PI4KB PRKDC	5.91e-03	16	136	2	SM00146
Domain	WD40_repeat_dom	KIF21B CFAP251 DDB1 ARHGEF10L TENM3 WDR90 LRBA	6.12e-03	297	136	7	IPR017986
Domain	CarboxyPept-like_regulatory	TENM4 TENM3	6.66e-03	17	136	2	IPR008969
Domain	Ig_E-set	PKHD1L1 PLXNC1 PKHD1 PLXNA2	7.06e-03	104	136	4	IPR014756
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ATP6V1A ACACA NOL6 BMS1 U2AF2 RAB14 PKHD1L1 BRCA1 TENM3 PI4KB DCLRE1A PRKDC LRBA PARD3 PCCA SEC23A	1.19e-07	777	141	16	35844135
Pubmed	Polymorphisms in genes of the steroid hormone biosynthesis and metabolism pathways and endometrial cancer risk.	CYP1A2 CYP19A1 GSTT1 HSD17B1	5.91e-07	17	141	4	20381444
Pubmed	Evaluation of genetic variations in the androgen and estrogen metabolic pathways as risk factors for sporadic and familial prostate cancer.	CYP1A2 CYP19A1 GSTT1 HSD17B1	3.06e-06	25	141	4	17507624
Pubmed	Estrogen-metabolizing gene polymorphisms in the assessment of breast carcinoma risk and fibroadenoma risk in Caucasian women.	CYP1A2 CYP19A1 HSD17B1	3.60e-06	8	141	3	15241822
Pubmed	Increased prevalence of EGFR-mutant lung cancer in women and in East Asian populations: analysis of estrogen-related polymorphisms.	CYP19A1 GSTT1 HSD17B1	3.60e-06	8	141	3	18593984
Pubmed	Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.	ABCA1 DHX38 GCKR AQP9 HPR	5.05e-06	61	141	5	22916037
Pubmed	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	KIF21B IKZF1 GCKR TYK2 SLC22A4 DNMT3A	8.21e-06	116	141	6	21102463
Pubmed	Association of testicular germ cell tumor with polymorphisms in estrogen receptor and steroid metabolism genes.	CYP1A2 CYP19A1 HSD17B1	1.05e-05	11	141	3	19776291
Pubmed	A Large-scale genetic association study of esophageal adenocarcinoma risk.	CYP1A2 ERCC5 CYP19A1 PTGS1 THBS1 BRCA1 BTNL2 HSD17B1 DDX39B	1.43e-05	351	141	9	20453000
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	FLOT2 SERBP1 CASP14 NOL6 RAB14 DDB1 BRCA1 NUP210 SUPT16H DCLRE1A PRKDC DDX39B	1.51e-05	652	141	12	31180492
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	SERBP1 TCF20 ACACA DHX38 NOL6 BMS1 U2AF2 DDB1 NUP210 DLD PRKDC SEC23A	1.53e-05	653	141	12	22586326
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	ATP6V1A SERBP1 ACACA DHX38 BRCA1 DCLRE1A PRKDC PCCA DDX39B	1.63e-05	357	141	9	37059091
Pubmed	Helios deficiency has minimal impact on T cell development and function.	IKZF2 IKZF1	1.63e-05	2	141	2	19620299
Pubmed	The association of genetic polymorphisms in sex hormone biosynthesis and action with insulin sensitivity and diabetes mellitus in women at midlife.	CYP19A1 HSD17B1	1.63e-05	2	141	2	16949391
Pubmed	Association of CYP19A1 and CYP1A2 genetic polymorphisms with type 2 diabetes mellitus risk in the Chinese Han population.	CYP1A2 CYP19A1	1.63e-05	2	141	2	32814585
Pubmed	Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1.	ACACA BRCA1	1.63e-05	2	141	2	18452305
Pubmed	Teneurins assemble into presynaptic nanoclusters that promote synapse formation via postsynaptic non-teneurin ligands.	TENM4 TENM3	1.63e-05	2	141	2	35484136
Pubmed	Structural basis for regulation of human acetyl-CoA carboxylase.	ACACA BRCA1	1.63e-05	2	141	2	29899443
Pubmed	Immunoexpression of aromatase cytochrome P450 and 17β-hydroxysteroid dehydrogenase in women's ovaries after menopause.	CYP19A1 HSD17B1	1.63e-05	2	141	2	24855493
Pubmed	Macronutrient intakes and serum oestrogen, and interaction with polymorphisms in CYP19A1 and HSD17B1 genes: a cross-sectional study in postmenopausal Japanese women.	CYP19A1 HSD17B1	1.63e-05	2	141	2	28980890
Pubmed	Cell cycle regulation of the BRCA1/acetyl-CoA-carboxylase complex.	ACACA BRCA1	1.63e-05	2	141	2	19061860
Pubmed	Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair.	PRKDC PARD3	1.63e-05	2	141	2	17287830
Pubmed	Effect of urban traffic, individual habits, and genetic polymorphisms on background urinary 1-hydroxypyrene excretion.	CYP1A2 GSTT1	1.63e-05	2	141	2	16406813
Pubmed	CYP1A2--a novel genetic marker for early aromatase inhibitor response in the treatment of breast cancer patients.	CYP1A2 CYP19A1	1.63e-05	2	141	2	27029552
Pubmed	Association Between CYP2D7 and TCF20 Polymorphisms and Coronary Heart Disease.	CYP2D7 TCF20	1.63e-05	2	141	2	39060884
Pubmed	Association of variants in BAT1-LTA-TNF-BTNL2 genes within 6p21.3 region show graded risk to leprosy in unrelated cohorts of Indian population.	BTNL2 DDX39B	1.63e-05	2	141	2	22071774
Pubmed	BRCA1 modulates the autophosphorylation status of DNA-PKcs in S phase of the cell cycle.	BRCA1 PRKDC	1.63e-05	2	141	2	25223785
Pubmed	Localization of blood proteins thrombospondin1 and ADAMTS13 to cerebral corpora amylacea.	ADAMTS13 THBS1	1.63e-05	2	141	2	19422532
Pubmed	BRCA1 is a novel regulator of metabolic function in skeletal muscle.	ACACA BRCA1	1.63e-05	2	141	2	24565757
Pubmed	Phosphatidylinositol-4 kinase III beta and oxysterol-binding protein accumulate unesterified cholesterol on poliovirus-induced membrane structure.	OSBP PI4KB	1.63e-05	2	141	2	24527995
Pubmed	Aromatase expression is increased in BRCA1 mutation carriers.	CYP19A1 BRCA1	1.63e-05	2	141	2	19445691
Pubmed	BRCA1 interacts with acetyl-CoA carboxylase through its tandem of BRCT domains.	ACACA BRCA1	1.63e-05	2	141	2	12360400
Pubmed	BRCA1 breast cancer risk is modified by CYP19 polymorphisms in Ashkenazi Jews.	CYP19A1 BRCA1	1.63e-05	2	141	2	19366906
Pubmed	Intragenic motifs regulate the transcriptional complexity of Pkhd1/PKHD1.	PKHD1 PRKDC	1.63e-05	2	141	2	24984783
Pubmed	[Correlation of serum ADAMTS13 and TSP1 levels with myocardial injury and prognosis in patients with acute coronary syndrome].	ADAMTS13 THBS1	1.63e-05	2	141	2	34134958
Pubmed	ACCA phosphopeptide recognition by the BRCT repeats of BRCA1.	ACACA BRCA1	1.63e-05	2	141	2	16698035
Pubmed	Genetic polymorphisms and obesity influence estradiol decline during the menopause.	CYP19A1 HSD17B1	1.63e-05	2	141	2	21198743
Pubmed	BRCA1 affects lipid synthesis through its interaction with acetyl-CoA carboxylase.	ACACA BRCA1	1.63e-05	2	141	2	16326698
Pubmed	Predominant interaction of both Ikaros and Helios with the NuRD complex in immature thymocytes.	IKZF2 IKZF1	1.63e-05	2	141	2	17681952
Pubmed	[Expression characteristics of isoforms of Ikaros and Helios in patients with leukemia and their mechanism].	IKZF2 IKZF1	1.63e-05	2	141	2	22931634
Pubmed	U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction.	U2AF2 DDX39B	1.63e-05	2	141	2	9242493
Pubmed	Reelin and aromatase cooperate in ovarian follicle development.	RELN CYP19A1	1.63e-05	2	141	2	29880879
Pubmed	Association between endometriosis and genetic polymorphisms of the estradiol-synthesizing enzyme genes HSD17B1 and CYP19.	CYP19A1 HSD17B1	1.63e-05	2	141	2	15640252
Pubmed	UIF, a New mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA.	SERBP1 SUPT16H DDX39B	1.81e-05	13	141	3	19836239
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	ATP6V1A FLOT2 CASP14 TCF20 NOL6 U2AF2 RAB14 DDB1 NUP210 SUPT16H CIZ1 PRKDC HEATR5B DDX39B SEC23A	1.90e-05	1024	141	15	24711643
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	ATP6V1A SERBP1 ACACA ACADL U2AF2 RAB14 DDB1 DLD PRKDC LRBA PCCA SEC23A SORD	2.66e-05	807	141	13	30575818
Pubmed	Genetic polymorphisms of estrogen metabolizing enzyme and breast cancer risk in Thai women.	CYP1A2 CYP19A1 HSD17B1	3.51e-05	16	141	3	19415745
Pubmed	Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.	RELN PLXNC1 PLXNA2	4.25e-05	17	141	3	11683995
Pubmed	Influence of polymorphisms in xenobiotic-metabolizing genes and DNA-repair genes on diepoxybutane-induced SCE frequency.	ERCC5 GSTT1 BRCA1	4.25e-05	17	141	3	17078101
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	KIF21B ATP6V1A PHF20 SASH1 ACADL U2AF2 RAB14 CRMP1 DLD PARD3 SEC23A	4.88e-05	621	141	11	22794259
Pubmed	Ten-m3 plays a role in the formation of thalamostriatal projections.	TENM3 EPHA7	4.88e-05	3	141	2	37700636
Pubmed	Additive genetic effect of GCKR, G6PC2, and SLC30A8 variants on fasting glucose levels and risk of type 2 diabetes.	SLC30A8 GCKR	4.88e-05	3	141	2	35657990
Pubmed	Signaling pathways regulating aromatase and cyclooxygenases in normal and malignant breast cells.	CYP19A1 PTGS1	4.88e-05	3	141	2	11897504
Pubmed	Polymorphisms in CYP19A1, HSD17B1 and HSD17B2 genes and serum sex hormone level among postmenopausal Japanese women.	CYP19A1 HSD17B1	4.88e-05	3	141	2	26323233
Pubmed	Thrombospondin-1 and ADAMTS13 competitively bind to VWF A2 and A3 domains in vitro.	ADAMTS13 THBS1	4.88e-05	3	141	2	20705333
Pubmed	Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs.	IKZF1 DDB1	4.88e-05	3	141	2	25108355
Pubmed	Adenomyosis: genetics of estrogen metabolism.	CYP1A2 CYP19A1	4.88e-05	3	141	2	30878995
Pubmed	Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors.	IKZF2 IKZF1	4.88e-05	3	141	2	9560339
Pubmed	Corticotropin-releasing hormone stimulates estrogen biosynthesis in cultured human placental trophoblasts.	CYP19A1 HSD17B1	4.88e-05	3	141	2	16467490
Pubmed	Analysis of Ikaros family splicing variants in human hematopoietic lineages.	IKZF2 IKZF1	4.88e-05	3	141	2	20432734
Pubmed	[Relationship between estrogen-biosynthesis gene (CYP17, CYP19, HSD17beta1) polymorphisms and breast cancer].	CYP19A1 HSD17B1	4.88e-05	3	141	2	20193327
Pubmed	Identification of placental nutrient transporters associated with intrauterine growth restriction and pre-eclampsia.	ABCA1 SLC7A7	4.88e-05	3	141	2	29499643
Pubmed	Targeting BRCA1-BER deficient breast cancer by ATM or DNA-PKcs blockade either alone or in combination with cisplatin for personalized therapy.	BRCA1 PRKDC	4.88e-05	3	141	2	25205036
Pubmed	Estrogen formation in endometrial and cervix cancer cell lines: involvement of aromatase, steroid sulfatase and 17beta-hydroxysteroid dehydrogenases (types 1, 5, 7 and 12).	CYP19A1 HSD17B1	4.88e-05	3	141	2	18817841
Pubmed	Polymorphisms in DNA repair genes, ionizing radiation exposure and risk of breast cancer in U.S. Radiologic technologists.	BRCA1 PRKDC	4.88e-05	3	141	2	17764108
Pubmed	Curcumin induces re‑expression of BRCA1 and suppression of γ synuclein by modulating DNA promoter methylation in breast cancer cell lines.	BRCA1 DNMT3A	4.88e-05	3	141	2	32020216
Pubmed	Aberrant Ikaros, Aiolos, and Helios expression in Hodgkin and non-Hodgkin lymphoma.	IKZF2 IKZF1	4.88e-05	3	141	2	18332232
Pubmed	XPG mRNA expression levels modulate prognosis in resected non-small-cell lung cancer in conjunction with BRCA1 and ERCC1 expression.	ERCC5 BRCA1	4.88e-05	3	141	2	19289372
Pubmed	De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells.	PRKDC DNMT3A	4.88e-05	3	141	2	17420264
Pubmed	Contribution of CYP19A1, CYP1A1, and CYP1A2 polymorphisms in coronary heart disease risk among the Chinese Han population.	CYP1A2 CYP19A1	4.88e-05	3	141	2	35380334
Pubmed	Maximal Oxygen Consumption Is Reduced in Aquaporin-1 Knockout Mice.	AQP9 RHAG	4.88e-05	3	141	2	27559317
Pubmed	G protein coupled oestrogen receptor 1, aromatase, 17β-HSD and cAMP level in mutational falsetto.	CYP19A1 HSD17B1	4.88e-05	3	141	2	31989268
Pubmed	Reelin signaling modulates GABAB receptor function in the neocortex.	RELN GABBR2	4.88e-05	3	141	2	32083308
Pubmed	Evaluating von Willebrand factor and ADAMTS13 levels in thalassemia major patients and assessing a possible association with Thrombospondin-1.	ADAMTS13 THBS1	4.88e-05	3	141	2	37438087
Pubmed	The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins.	DHX38 SUPT16H	4.88e-05	3	141	2	10421373
Pubmed	Overexpression of novel short isoforms of Helios in a patient with T-cell acute lymphoblastic leukemia.	IKZF2 IKZF1	4.88e-05	3	141	2	11937265
Pubmed	CYP1A2, GSTM1, and GSTT1 polymorphisms and diet effects on CYP1A2 activity in a crossover feeding trial.	CYP1A2 GSTT1	4.88e-05	3	141	2	19843669
Pubmed	First-in-Class Allosteric Inhibitors of DNMT3A Disrupt Protein-Protein Interactions and Induce Acute Myeloid Leukemia Cell Differentiation.	KDM5A DNMT3A	4.88e-05	3	141	2	35866897
Pubmed	Thrombospondin 1 and Reelin act through Vldlr to regulate cardiac growth and repair.	RELN THBS1	4.88e-05	3	141	2	38147128
Pubmed	Correlation of BRCA1, TXR1 and TSP1 mRNA expression with treatment outcome to docetaxel-based first-line chemotherapy in patients with advanced/metastatic non-small-cell lung cancer.	THBS1 BRCA1	4.88e-05	3	141	2	21157449
Pubmed	SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter.	ABCA1 PARD3	4.88e-05	3	141	2	18484747
Pubmed	Plexina2 and CRMP2 Signaling Complex Is Activated by Nogo-A-Liganded Ngr1 to Restrict Corticospinal Axon Sprouting after Trauma.	CRMP1 PLXNA2	4.88e-05	3	141	2	30804090
Pubmed	Expression patterns of Ikaros family members during positive selection and lineage commitment of human thymocytes.	IKZF2 IKZF1	4.88e-05	3	141	2	27502439
Pubmed	The depletion of Circ-PRKDC enhances autophagy and apoptosis in T-cell acute lymphoblastic leukemia via microRNA-653-5p/Reelin mediation of the PI3K/AKT/mTOR signaling pathway.	RELN PRKDC	4.88e-05	3	141	2	33615686
Pubmed	Specific pattern of LKB1 and phospho-acetyl-CoA carboxylase protein immunostaining in human normal tissues and lung carcinomas.	ACACA STK11IP	4.88e-05	3	141	2	17521700
Pubmed	OSBP negatively regulates ABCA1 protein stability.	ABCA1 OSBP	4.88e-05	3	141	2	18450749
Pubmed	Control of insulin granule formation and function by the ABC transporters ABCG1 and ABCA1 and by oxysterol binding protein OSBP.	ABCA1 OSBP	4.88e-05	3	141	2	29540530
Pubmed	BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II-DNA complexes.	BRCA1 PRKDC	4.88e-05	3	141	2	30352856
Pubmed	Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning.	SERBP1 CRMP1 TENM4 TENM3	5.58e-05	51	141	4	16919471
Pubmed	Network organization of the human autophagy system.	CASP14 ACACA DDB1 RAB3GAP1 TRABD PI4KB SUPT16H PRKDC KLHDC10	7.80e-05	437	141	9	20562859
Pubmed	AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development.	ACACA GABBR2 PARD3	8.22e-05	21	141	3	19217427
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	ATP6V1A ACACA KDM5A DHX38 NOL6 BMS1 U2AF2 IKZF1 RAB14 RCC1L SUPT16H DLD PRKDC LRBA PCCA DDX39B	9.32e-05	1318	141	16	30463901
Pubmed	Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.	TENM4 TENM3	9.74e-05	4	141	2	10225957
Pubmed	Structural basis for the BRCA1 BRCT interaction with the proteins ATRIP and BAAT1.	ATRIP BRCA1	9.74e-05	4	141	2	24073851
Pubmed	RNA interferences targeting the Fanconi anemia/BRCA pathway upstream genes reverse cisplatin resistance in drug-resistant lung cancer cells.	FANCL BRCA1	9.74e-05	4	141	2	26385482
Pubmed	Polymorphisms in metabolic genes related to tobacco smoke and the risk of gastric cancer in the European prospective investigation into cancer and nutrition.	CYP1A2 GSTT1	9.74e-05	4	141	2	17164366
Pubmed	[Analysis of polymorphisms in genes of insulin receptor substrate-1 and enzymes involved in estrogen biosynthesis and metabolism among breast cancer patients with BRCA1 mutations].	CYP19A1 BRCA1	9.74e-05	4	141	2	19514368
Pubmed	The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins.	IKZF1 DDB1	9.74e-05	4	141	2	24292623
Pubmed	CYP1A1, CYP19, and GSTM1 polymorphisms increase the risk of endometriosis.	CYP19A1 GSTT1	9.74e-05	4	141	2	12620480
Pubmed	Dietary isoflavone intake, polymorphisms in the CYP17, CYP19, 17beta-HSD1, and SHBG genes, and risk of breast cancer in case-control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians.	CYP19A1 HSD17B1	9.74e-05	4	141	2	20432167
Cytoband	11q12-q13	DDB1 OSBP	1.39e-04	6	141	2	11q12-q13
Cytoband	Ensembl 112 genes in cytogenetic band chr22q13	CERK CYP2D7 TCF20 PKDREJ TRABD SELENOO	5.73e-04	330	141	6	chr22q13
Cytoband	8p11.23	GOT1L1 KCNU1	6.06e-04	12	141	2	8p11.23
GeneFamily	Plexins	PLXNC1 PLXNA2	7.34e-04	9	83	2	683
GeneFamily	EF-hand domain containing\|Diacylglycerol kinases	DGKQ DGKZ	9.15e-04	10	83	2	1178
ToppCell	E12.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	THEMIS2 RELN FLT4 IKZF1 SLC7A7 CRMP1 ACOD1 BTNL2	5.25e-08	163	141	8	c21114826bee1b05b411984326fef6b6e0d05316
ToppCell	E12.5-Endothelial-lymphatic_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	THEMIS2 RELN FLT4 IKZF1 SLC7A7 CRMP1 ACOD1 BTNL2	5.25e-08	163	141	8	5d49414432db259a19df50d7944581d00b69f537
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPYS MACC1 ADCY2 MYO3A PKHD1 PARD3 UNC5D EPHA7	1.45e-07	186	141	8	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	PCW_05-06-Hematologic_ErythroMegGranulo-Hem_ErythroMeg\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FLOT2 RELN IKZF1 CR1 PKHD1L1 PTGS1 RHAG SLC22A4	1.58e-07	188	141	8	5d6faf45a9c0794b0c30b0a0601c10afbb8aa9ed
ToppCell	PCW_05-06-Hematologic_ErythroMegGranulo\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FLOT2 RELN IKZF1 CR1 PKHD1L1 PTGS1 RHAG SLC22A4	1.58e-07	188	141	8	a0873783f0a2cd852563c05a275dddc72905ced2
ToppCell	PCW_05-06-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-erythro\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FLOT2 RELN IKZF1 CR1 PKHD1L1 PTGS1 RHAG SLC22A4	1.58e-07	188	141	8	29d804232d974a8c0029300345b287005b09bade
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DPYS MACC1 MYO3A TENM3 PKHD1 PARD3 UNC5D EPHA7	1.64e-07	189	141	8	28b502611829e4a24caff2562545c7db97686099
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 IKZF2 ACADL PTGS1 TENM3 PKHD1 PXYLP1 LRBA	2.01e-07	194	141	8	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RELN FLT4 SASH1 KIF26B PKHD1L1 CRMP1 PLXNA2	9.83e-07	165	141	7	50a8513d8d2630861499393a7f102b35366bad37
ToppCell	Endothelial-B-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	DLGAP2 RELN FLT4 PTCHD3 PKHD1L1 UNC5D DOC2B	1.11e-06	168	141	7	4977c3837fbb1f36c89fddd5764e37290ac25ad8
ToppCell	Endothelial-B-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	DLGAP2 RELN FLT4 PTCHD3 PKHD1L1 TENM3 DOC2B	1.15e-06	169	141	7	95c617143e1fbdd1d55a93ffdcc210e0be37cf2f
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RELN KIF26B MYO3A TENM4 TENM3 PKHD1 PARD3	1.63e-06	178	141	7	544379f5a6145429762258d426b876bb36c112f5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 SASH1 ACADL PKHD1 PARD3 UNC5D EPHA7	1.82e-06	181	141	7	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 ARHGEF10L CRMP1 PKHD1 PARD3 UNC5D EPHA7	1.96e-06	183	141	7	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN KIF26B PKHD1L1 TENM4 PKHD1 UNC5D EPHA7	2.03e-06	184	141	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN KIF26B PKHD1L1 TENM4 PKHD1 UNC5D EPHA7	2.03e-06	184	141	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN KIF26B PKHD1L1 TENM4 PKHD1 UNC5D EPHA7	2.03e-06	184	141	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	PCW_07-8.5-Hematologic_ErythroMegGranulo-Hem_ErythroMeg\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RELN IKZF1 CR1 PKHD1L1 PTGS1 RHAG SLC22A4	2.18e-06	186	141	7	3b60a153e6cfc1b977a1f8b8f3bcaf75d1f4ff5b
ToppCell	PCW_07-8.5-Hematologic_ErythroMegGranulo\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RELN IKZF1 CR1 PKHD1L1 PTGS1 RHAG SLC22A4	2.18e-06	186	141	7	294839944266407c40ef86e1d3e0fce4652b70ff
ToppCell	PCW_07-8.5-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-erythro\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RELN IKZF1 CR1 PKHD1L1 PTGS1 RHAG SLC22A4	2.18e-06	186	141	7	6078aa16261554c7fd41137b8de1362d15b30490
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 SASH1 CRMP1 PKHD1 PARD3 UNC5D EPHA7	2.34e-06	188	141	7	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 KIF26B MYO3A PKHD1 PARD3 UNC5D EPHA7	2.43e-06	189	141	7	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 IKZF2 ACADL TENM3 PKHD1 PXYLP1 LRBA	2.60e-06	191	141	7	3e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 KIF26B MYO3A PKHD1 PARD3 UNC5D EPHA7	2.60e-06	191	141	7	1cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 ACADL PTGS1 TENM3 PKHD1 PXYLP1 LRBA	2.89e-06	194	141	7	69bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell	distal-Endothelial-Lymphatic-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DLGAP2 RELN FLT4 PTCHD3 PKHD1L1 MARCHF4 DOC2B	3.09e-06	196	141	7	b0f23dc802a2c2a56a08d398a464ea78b58ade4c
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|lung / Disease (COVID-19 only), tissue and cell type	THEMIS2 IKZF1 SLC7A7 CR1 JAML AQP9 PLXNC1	3.19e-06	197	141	7	a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	THEMIS2 IKZF1 SLC7A7 CR1 JAML AQP9 PLXNC1	3.30e-06	198	141	7	ea34096bee852a7e996f097fa279381afa8f86ff
ToppCell	distal-1-Endothelial-Lymphatic\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DLGAP2 RELN FLT4 PTCHD3 PKHD1L1 MARCHF4 DOC2B	3.30e-06	198	141	7	b6fea363463c8dd7e6780c085ece4900266a6286
ToppCell	proximal-Hematologic-Classical_Monocyte-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	THEMIS2 SLC7A7 CR1 JAML AQP9 THBS1 PLXNC1	3.30e-06	198	141	7	6a7ca6eef6b74aa7fc3aec84e9ffd0beedaa589b
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DLGAP2 RELN FLT4 SASH1 PKHD1L1 RHAG DOC2B	3.30e-06	198	141	7	b3a020522e064bb61949d38e442f24026e339364
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DLGAP2 RELN FLT4 SASH1 PKHD1L1 RHAG DOC2B	3.30e-06	198	141	7	fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCell	proximal-3-Hematologic-Classical_Monocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	THEMIS2 SLC7A7 CR1 JAML AQP9 THBS1 PLXNC1	3.30e-06	198	141	7	6c6a63b8ec03b7a8f46b70bf13261fab56355f92
ToppCell	proximal-Hematologic-Classical_Monocyte\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	THEMIS2 SLC7A7 CR1 JAML AQP9 THBS1 PLXNC1	3.30e-06	198	141	7	98bd2b3e03ab659ce163d5773660ce008e4cc2ca
ToppCell	Tracheal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	THEMIS2 SLC7A7 CR1 AQP9 ARHGEF10L THBS1 PLXNC1	3.41e-06	199	141	7	4e0b73d88b1345ec63a9e5629762341e75beb47f
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Monocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THEMIS2 IKZF1 SLC7A7 JAML AQP9 PTGS1 PLXNC1	3.53e-06	200	141	7	48ce43a27e78b2883e588e1a63fa5352c2deeeb7
ToppCell	Bronchus_Control_(B.)-Immune-TX-MoAM-1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	THEMIS2 ABCA1 SLC7A7 JAML AQP9 THBS1 PLXNC1	3.53e-06	200	141	7	fe7f8b04067b6680b69c8523f0fa514ef97207e2
ToppCell	PND01-Immune-Immune_Myeloid-DC-cDC2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZC3H12A SZT2 SLC7A7 JAML TYK2 KIAA0825	9.06e-06	152	141	6	cefc0ab592e99badf145fb95adf9906cb81be81c
ToppCell	PND01-Immune-Immune_Myeloid-DC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZC3H12A SZT2 SLC7A7 JAML TYK2 KIAA0825	9.06e-06	152	141	6	c8faa83dcaddb2ce2bb890f90dd8e676f7dcb1b3
ToppCell	PND01-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZC3H12A SZT2 SLC7A7 JAML TYK2 KIAA0825	9.06e-06	152	141	6	c3f00beb8b6fde99263d5ed6bbe3c2415d02f91d
ToppCell	facs-Heart-RV-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKDREJ JAML AQP9 ACOD1 CKM THBS1	1.13e-05	158	141	6	2a222301474c4dfd9a776e197c10f4c1cacceb62
ToppCell	facs-Heart-RV-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKDREJ JAML AQP9 ACOD1 CKM THBS1	1.13e-05	158	141	6	ff9878fd768f22bf2ee4805bac2ba01cb3cb804a
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1A2 DPYS ACACA GCKR AQP9 SORD	1.21e-05	160	141	6	c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCell	Sigmoid-Macrophage-Macrophage\|Macrophage / Region, Cell class and subclass	MACC1 ABCA1 SASH1 EI24 JAML PLXNC1	1.60e-05	168	141	6	bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SASH1 KIF26B ARHGEF10L CRMP1 PKHD1 EPHA7	1.71e-05	170	141	6	5d5f208682be21ed58320f5fc083a7898f8712da
ToppCell	Endothelial-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	DLGAP2 RELN FLT4 KIF26B PKHD1L1 DOC2B	1.83e-05	172	141	6	d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCell	metastatic_Lymph_Node-Endothelial_cells-Lymphatic_ECs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	DLGAP2 RELN FLT4 EHD2 THBS1 DOC2B	1.95e-05	174	141	6	d551bc29afef071adf4c9bb80345352ec33441d8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SASH1 CRMP1 PKHD1 PARD3 UNC5D EPHA7	2.08e-05	176	141	6	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D231\|Adult / Lineage, Cell type, age group and donor	DLGAP2 RELN FLT4 PKHD1L1 TENM3 DOC2B	2.22e-05	178	141	6	c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO3A TENM4 TENM3 PARD3 CNN1 UNC5D	2.22e-05	178	141	6	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	THEMIS2 DLGAP2 RELN FLT4 PKHD1L1 DOC2B	2.29e-05	179	141	6	ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	THEMIS2 DLGAP2 RELN FLT4 PKHD1L1 DOC2B	2.29e-05	179	141	6	35fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCell	renal_papilla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	IKZF2 SASH1 KIF26B PTGS1 PXYLP1 LRBA	2.36e-05	180	141	6	49829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell	LPS-IL1RA-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THEMIS2 IKZF1 SLC7A7 ARHGEF10L ACOD1 PLXNC1	2.36e-05	180	141	6	97241f62ee133dcb0d4855ffda5dd1349de9f7b2
ToppCell	LPS-IL1RA-Myeloid-Monocytes,_Macrophages\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THEMIS2 IKZF1 SLC7A7 ARHGEF10L ACOD1 PLXNC1	2.36e-05	180	141	6	41896546cd1cc458e08c0d4e19aa4860e5d4fcd6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SASH1 ARHGEF10L CRMP1 PKHD1 UNC5D EPHA7	2.44e-05	181	141	6	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SASH1 CRMP1 PKHD1 PARD3 UNC5D EPHA7	2.52e-05	182	141	6	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SASH1 ARHGEF10L CRMP1 PKHD1 UNC5D EPHA7	2.52e-05	182	141	6	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF10L CRMP1 PKHD1 PARD3 UNC5D EPHA7	2.59e-05	183	141	6	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	cellseq2-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	THEMIS2 SLC7A7 JAML PTGS1 CKM PLXNC1	2.59e-05	183	141	6	9840706f972387241bf1d4ba8af25efc3214a91b
ToppCell	cellseq2-Immune-Immune_Myeloid-Myeloid_Dendritic\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	THEMIS2 SLC7A7 JAML PTGS1 CKM PLXNC1	2.59e-05	183	141	6	409cb52cf4c967e52bf75a6680bcbe87f638c75d
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RELN FLT4 PTCHD3 PKDREJ PKHD1L1 TENM3	2.67e-05	184	141	6	e5756afa3181186f9b65552b8df5359ef4024bee
ToppCell	COVID-19-Neuronal_cells-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	DLGAP2 RELN FLT4 SASH1 PKHD1L1 DOC2B	2.76e-05	185	141	6	4a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	THEMIS2 DLGAP2 RELN FLT4 PKHD1L1 DOC2B	2.76e-05	185	141	6	3be9e05b929ac4d956b1d53284072f668a6c1959
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN ABCA1 FLT4 B3GNT7 PKHD1L1 SORD	2.76e-05	185	141	6	59acaf025353405948dc34ccccf37ec5c08ea903
ToppCell	COVID-19-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	DLGAP2 RELN FLT4 SASH1 PKHD1L1 DOC2B	2.76e-05	185	141	6	36ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-lymphatic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	THEMIS2 DLGAP2 RELN FLT4 PKHD1L1 DOC2B	2.76e-05	185	141	6	c3dd64a726cb8a1fe048683c266b7532a714a52e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 KIF26B PKHD1 PARD3 UNC5D EPHA7	2.84e-05	186	141	6	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPYS MACC1 PKHD1 PARD3 UNC5D EPHA7	2.93e-05	187	141	6	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D175\|Adult / Lineage, Cell type, age group and donor	DLGAP2 RELN FLT4 KIF26B PKHD1L1 DOC2B	2.93e-05	187	141	6	1e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DLGAP2 RELN FLT4 KIF26B PKHD1L1 DOC2B	3.02e-05	188	141	6	c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell	5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN FLT4 SASH1 PKHD1L1 EHD2 DOC2B	3.02e-05	188	141	6	524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell	5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN FLT4 SASH1 PKHD1L1 EHD2 DOC2B	3.02e-05	188	141	6	d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DLGAP2 RELN FLT4 KIF26B PKHD1L1 DOC2B	3.02e-05	188	141	6	2db80767903703e7e0a1a37c598f7877a909ee94
ToppCell	COPD-Epithelial-Mesothelial\|Epithelial / Disease state, Lineage and Cell class	DLGAP2 PKHD1L1 AQP9 PTGS1 TENM3 HPR	3.02e-05	188	141	6	159d63ecc3653a7449fc6acefd6ef0464845260e
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	DPYS MACC1 PKHD1 PARD3 UNC5D EPHA7	3.11e-05	189	141	6	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP2 RELN FLT4 SASH1 PKHD1L1 RHAG	3.20e-05	190	141	6	876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DLGAP2 RELN FLT4 SASH1 PKHD1L1 DOC2B	3.20e-05	190	141	6	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPYS MACC1 PKHD1 PARD3 UNC5D EPHA7	3.20e-05	190	141	6	989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCell	PBMC-Severe-cDC_12\|Severe / Compartment, Disease Groups and Clusters	MEX3D BRCA1 NUP210 SUPT16H WDR90 PRKDC	3.20e-05	190	141	6	84ee185939bdefb10705b621a70da27701eadcee
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP2 RELN FLT4 SASH1 PKHD1L1 RHAG	3.20e-05	190	141	6	be9f36127028f52ca5fc1b32ba15a6c26aad69ac
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP2 RELN FLT4 SASH1 PKHD1L1 RHAG	3.20e-05	190	141	6	09a8855901c3c9332dbaab3e40166485b696d0f1
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SASH1 CRMP1 PKHD1 PARD3 UNC5D EPHA7	3.30e-05	191	141	6	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 MACC1 IKZF2 ACADL ADCY2 PKHD1	3.30e-05	191	141	6	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 SLC30A8 GABBR2 SEPSECS TENM3 PARD3	3.39e-05	192	141	6	5b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MACC1 GALNT3 ACADL MYO3A NUP210 PKHD1	3.39e-05	192	141	6	d3634574b2e8d2ded6446969361b70761b331aea
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D175\|Adult / Lineage, Cell type, age group and donor	ATP6V1A ABCA1 SLC7A7 CR1 AQP9 ARHGEF10L	3.39e-05	192	141	6	733491e932350e3c216a626cc49c3cd3fe970a82
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte2_(4)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ZC3H12A IKZF1 SLC7A7 JAML AQP9 ACOD1	3.39e-05	192	141	6	aa65557b35d3eba9f24b970849255d05174d1c05
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MACC1 GALNT3 ACADL MYO3A NUP210 PKHD1	3.39e-05	192	141	6	1aa5e4d9b32013a3f272561dcb8377f6805706df
ToppCell	Children_(3_yrs)-Immune-monocyte-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DLGAP2 IKZF1 CR1 JAML PTGS1 PLXNC1	3.49e-05	193	141	6	58e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCell	PCW_05-06-Epithelial-Epithelial_proliferating\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MACC1 GALNT3 ACADL MYO3A NUP210 PKHD1	3.49e-05	193	141	6	5f0eba7b1440beb891d94a288f7f18a4e13c3a88
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DLGAP2 RELN FLT4 SASH1 KIF26B PKHD1L1	3.49e-05	193	141	6	bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCell	(2)_MNPs\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	THEMIS2 SLC7A7 JAML AQP9 THBS1 PLXNC1	3.60e-05	194	141	6	9cd64e325ec233da82c463b09262efe93d2a92ee
ToppCell	IPF-Epithelial-Mesothelial\|Epithelial / Disease state, Lineage and Cell class	DLGAP2 DPYS PKHD1L1 AQP9 TENM3 HPR	3.60e-05	194	141	6	d8a26da856a85e3d001d406e992cb18fdd58baef
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 MACC1 IKZF2 ACADL ADCY2 PKHD1	3.60e-05	194	141	6	f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell	PCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MACC1 GALNT3 ACADL MYO3A NUP210 PKHD1	3.70e-05	195	141	6	b78db0d929be6b04055805ea5ffecc56c47ba956
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 ARHGEF10L PKHD1 LRBA PARD3 PCCA	3.70e-05	195	141	6	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	Children_(3_yrs)-Endothelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DLGAP2 RELN FLT4 SASH1 PKHD1L1 DOC2B	3.70e-05	195	141	6	094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC7A7 CR1 JAML AQP9 THBS1 PLXNC1	3.81e-05	196	141	6	f811958823380069077754283e36106d80147494
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MACC1 IKZF2 GALNT3 ACADL NUP210 PKHD1	3.81e-05	196	141	6	7b17d47b7758d8ccf9dbefd097aeb553791a1eed
Computational	Genes in the cancer module 41.	KIF21B ABCA1 PHF20 ACACA SZT2 RHBDL1 FANCL IKZF1 PTGS1 GSTT1 PPP3CC PPT2 HPR HSD17B1 PARD3 PLXNA2	1.60e-05	566	90	16	MODULE_41
Drug	Sulfasalazine [599-79-1]; Down 200; 10uM; MCF7; HT_HG-U133A	IKZF1 GABBR2 CR1 EHD2 THBS1 MGAT2 BRCA1 PDE8B PARD3 DNMT3A	4.13e-07	196	141	10	5446_DN
Drug	glutarate	DPYS ACACA ACADL CKM LDB1 NUP210 DLD	3.18e-06	101	141	7	CID000000743
Drug	Vidarabine [5536-17-4]; Down 200; 15uM; PC3; HT_HG-U133A	SASH1 DHX38 U2AF2 ATP13A2 PPP3CC PI4KB KATNIP KLHDC10 SEC23A	3.64e-06	195	141	9	5850_DN
Drug	Oxprenolol hydrochloride [6452-73-9]; Up 200; 13.2uM; HL60; HT_HG-U133A	CYP1A2 GALNT3 CYP19A1 ADAMTS13 GCKR ATP13A2 GSTT1 THBS1 ZFYVE9	4.13e-06	198	141	9	6145_UP
Drug	radicicol, diheterospora chlamydosporia; Down 200; 0.1uM; HL60; HT_HG-U133A	PHF20 GABBR2 ATP13A2 ZFYVE9 PLXNC1 PDE8B PI4KB PCCA EDRF1	4.30e-06	199	141	9	2679_DN
Drug	Metrizamide [31112-62-6]; Down 200; 5uM; PC3; HT_HG-U133A	PHF20 SZT2 U2AF2 GABBR2 MGAT2 TENM4 TENM3 PLXNC1 ZNF839	4.48e-06	200	141	9	4075_DN
Drug	perfluorododecanoic acid	CYP1A2 ACACA ACADL CYP19A1	6.32e-06	20	141	4	CID000067545
Drug	N-benzylformamide	CYP1A2 CYP2D7 CYP19A1 SUPT16H RHOF SORD	7.76e-06	76	141	6	CID000080654
Drug	benzyloxyresorufin	CYP1A2 CYP2D7 PTCHD3 CYP19A1 RHOF SORD	9.03e-06	78	141	6	CID000114982
Drug	daidzein	CYP1A2 ABCA1 CFAP251 ERCC5 KDM5A CYP19A1 BRCA1 HSD17B1 EDRF1	1.08e-05	223	141	9	ctd:C004742
Drug	geldanamycin; Up 200; 1uM; PC3; HT_HG-U133A	CYP1A2 ABCA1 FLT4 SZT2 SLC7A7 PLXNC1 TRABD EDRF1	2.14e-05	186	141	8	1228_UP
Drug	Diphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; PC3; HT_HG-U133A	ATP6V1A ABCA1 U2AF2 THBS1 MGAT2 BRCA1 PRKDC SEC23A	2.59e-05	191	141	8	4299_DN
Drug	nitrotyrosine	CYP1A2 DPYS ABCA1 PTGS1 CKM ZFYVE9	2.97e-05	96	141	6	CID000065124
Drug	Chelidonine monohydrate (+) [476-32-4]; Up 200; 10.8uM; PC3; HT_HG-U133A	FLT4 CRMP1 MYO3A TENM3 PLXNC1 NUP210 PRDM14 DNMT3A	3.00e-05	195	141	8	5760_UP
Drug	Metergoline [17692-51-2]; Down 200; 10uM; PC3; HT_HG-U133A	PHF20 GRK4 IKZF1 CRMP1 PDE8B PI4KB DCLRE1A CNN1	3.12e-05	196	141	8	6744_DN
Drug	clotrimazole	CYP1A2 CYP2D7 CYP19A1 IKZF1 PTGS1 GSTT1 RHOF	3.12e-05	143	141	7	CID000002812
Drug	Sulindac [38194-50-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A	FLOT2 FLT4 PHF20 SZT2 RAB14 PDE8B PCCA EDRF1	3.23e-05	197	141	8	5528_UP
Drug	AH23848 hemicalcium salt hydrate; Down 200; 1uM; MCF7; HT_HG-U133A	ATP6V1A MEX3D U2AF2 ATP13A2 BRCA1 PI4KB PRKDC SEC23A	3.23e-05	197	141	8	6903_DN
Drug	Benzydamine hydrochloride [132-69-4]; Down 200; 11.6uM; PC3; HT_HG-U133A	ABCA1 NOL6 U2AF2 TENM4 ZFYVE9 PDE8B TRABD CIZ1	3.23e-05	197	141	8	5811_DN
Drug	Norethynodrel [68-23-5]; Down 200; 13.4uM; PC3; HT_HG-U133A	ZC3H12A UBE3B LDB1 TRABD NUP210 DCLRE1A ZNF839 PCCA	3.35e-05	198	141	8	1818_DN
Drug	Ampicillin trihydrate [7177-48-2]; Down 200; 10uM; PC3; HT_HG-U133A	CYP1A2 ABCA1 ZC3H12A DHX38 GABBR2 RAB3GAP1 LDB1 NUP210	3.35e-05	198	141	8	6307_DN
Drug	AC1Q3G0K	CYP1A2 CYP2D7 CYP19A1 ADCY2 SORD	3.52e-05	60	141	5	CID000002087
Drug	1,1-dichloroethylene	CYP1A2 CYP2D7 CYP19A1 DDB1 SORD	3.52e-05	60	141	5	CID000006366
Drug	Acetohexamide [968-81-0]; Down 200; 12.4uM; PC3; HT_HG-U133A	DHX38 RAB3GAP1 PPP3CC PI4KB NUP210 CIZ1 PARD3 ZNF839	3.60e-05	200	141	8	1829_DN
Drug	aranidipine	CYP1A2 ABCA1	3.81e-05	2	141	2	ctd:C059427
Drug	AC1NDTNH	DLGAP2 GALNT3 RHBDL1 IKZF1 GCKR JAML GSTT1 SEPSECS SUPT16H HSD17B1	5.70e-05	343	141	10	CID004631409
Drug	6beta-hydroxytestosterone	CYP1A2 CYP2D7 CYP19A1 RHOF	7.94e-05	37	141	4	CID000065543
Drug	AC1L1ILY	CYP1A2 CYP2D7 CYP19A1 RHBDL1	8.83e-05	38	141	4	CID000004635
Drug	chloral	CYP1A2 CYP2D7 ACACA CYP19A1 PTGS1	9.09e-05	73	141	5	CID000006407
Drug	11,14,15-THET	CYP1A2 CYP2D7 CYP19A1 PTGS1	9.80e-05	39	141	4	CID006439531
Drug	anti-BaPDE	CYP1A2 CYP2D7 CYP19A1 PTGS1 GSTT1 THBS1 BRCA1 SUPT16H	1.08e-04	234	141	8	CID000041322
Drug	20 alpha-dihydroprogesterone	SERBP1 CYP19A1 PTGS1 HSD17B1	1.08e-04	40	141	4	CID000008956
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A	KIF21B GABBR2 PTGS1 OSBP MGAT2 EDRF1 DNMT3A	1.12e-04	175	141	7	5222_UP
Drug	alpha-cyano-3-hydroxycinnamate	ACACA DLD	1.14e-04	3	141	2	CID006438323
Drug	halowax 1051	CYP19A1 HSD17B1	1.14e-04	3	141	2	ctd:C571106
Drug	5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole-3',5'-monophosphorothioate	ABCA1 IKZF1	1.14e-04	3	141	2	ctd:C071644
Drug	cyhexatin	CYP19A1 HSD17B1	1.14e-04	3	141	2	ctd:C001765
Drug	carboxybiotin	ACACA DLD PCCA	1.23e-04	16	141	3	CID000165526
Drug	BP-7,8-diol	CYP1A2 CYP2D7 CYP19A1 PTGS1 GSTT1	1.25e-04	78	141	5	CID000025892
Drug	11,12,15-trihydroxyeicosatrienoic acid	CYP1A2 CYP2D7 CYP19A1 PTGS1	1.31e-04	42	141	4	CID006439610
Drug	sebacate	ATP6V1A ERCC5 CYP2D7 ACADL BRCA1 DCLRE1A PRKDC	1.38e-04	181	141	7	CID000005192
Drug	Anisomycin [22862-76-6]; Down 200; 15uM; HL60; HT_HG-U133A	KIF21B CERK FLOT2 IKZF1 NUP210 CIZ1 RHOF	1.48e-04	183	141	7	1304_DN
Drug	atosiban	CYP19A1 FANCL PTGS1	1.48e-04	17	141	3	CID000068613
Drug	Benzofurans	CYP1A2 CYP19A1 HSD17B1	1.77e-04	18	141	3	ctd:D001572
Drug	Ivermectin [70288-86-7]; Up 200; 4.6uM; MCF7; HT_HG-U133A	KIF21B DPYS FLT4 DGKQ THBS1 MGAT2 DYRK1B	1.80e-04	189	141	7	7206_UP
Drug	Promethazine hydrochloride [58-33-3]; Down 200; 12.4uM; PC3; HT_HG-U133A	ATP6V1A ABCA1 UBE3B BRCA1 PDE8B KLHDC10 SEC23A	1.80e-04	189	141	7	6717_DN
Drug	ellipticine	CYP1A2 MACC1 IKZF1 DDB1	1.88e-04	46	141	4	CID000003213
Drug	NO-1886	CYP1A2 ABCA1 ACADL PTGS1	1.88e-04	46	141	4	CID000131601
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A	CYP1A2 NOL6 PTGS1 PDE8B TRABD PARD3 EDRF1	1.92e-04	191	141	7	5581_DN
Drug	clozapine; Down 200; 10uM; HL60; HT_HG-U133A	ZC3H12A PHF20 SZT2 ZFYVE9 PI4KB PARD3 EDRF1	1.98e-04	192	141	7	6188_DN
Drug	Butacaine [149-16-6]; Down 200; 13uM; MCF7; HT_HG-U133A	FLOT2 IKZF1 PTGS1 ZFYVE9 HSD17B1 PARD3 EDRF1	1.98e-04	192	141	7	3469_DN
Drug	Flunisolide [3385-03-3]; Up 200; 9.2uM; PC3; HT_HG-U133A	SZT2 U2AF2 GABBR2 CCIN PRDM14 EDRF1 PLXNA2	1.98e-04	192	141	7	4303_UP
Drug	C14802	CYP1A2 CYP2D7 CYP19A1 GSTT1	2.04e-04	47	141	4	CID011954053
Drug	Vitamin K2 [11032-49-8]; Up 200; 9uM; MCF7; HT_HG-U133A	PHF20 RHBDL1 ADCY2 EHD2 THBS1 ZFYVE9 CNN1	2.05e-04	193	141	7	3880_UP
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A	RELN NOL6 ADAMTS13 PTGS1 MGAT2 BRCA1 PDE8B	2.05e-04	193	141	7	5602_DN
Drug	Tocainide hydrochloride; Up 200; 17.4uM; MCF7; HT_HG-U133A	RAB14 DDB1 PTGS1 PI4KB CIZ1 PRKDC PARD3	2.11e-04	194	141	7	4838_UP
Drug	Clobetasol propionate [25122-46-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A	ABCA1 SZT2 KDM5A CRMP1 EHD2 DYRK1B CNN1	2.11e-04	194	141	7	6835_UP
Drug	Isradipine [75695-93-1]; Down 200; 10.8uM; PC3; HT_HG-U133A	ABCA1 ZC3H12A GABBR2 CIZ1 KATNIP DCLRE1A ZNF839	2.11e-04	194	141	7	6347_DN
Drug	17-AAG; Up 200; 0.1uM; MCF7; HG-U133A	ACACA GABBR2 EHD2 TRABD DYRK1B KLHDC10 PRDM14	2.18e-04	195	141	7	221_UP
Drug	Oxamniquine [21738-42-1]; Up 200; 14.4uM; HL60; HT_HG-U133A	SZT2 ADAMTS13 PKDREJ ATP13A2 ADCY2 AQP9 DNMT3A	2.18e-04	195	141	7	2924_UP
Drug	H-89, Dihydrochloride; Down 200; 0.5uM; PC3; HT_HG-U133A	ATP6V1A PHF20 U2AF2 RAB3GAP1 TRABD DCLRE1A PRKDC	2.18e-04	195	141	7	6921_DN
Drug	Clomiphene citrate (Z,E) [50-41-9]; Down 200; 6.6uM; HL60; HT_HG-U133A	ABCA1 ZC3H12A MEX3D IKZF1 CIZ1 KATNIP PARD3	2.18e-04	195	141	7	1269_DN
Drug	Torsemide [56211-40-6]; Down 200; 11.4uM; HL60; HT_HG-U133A	THEMIS2 FLOT2 UBE3B IKZF1 MGAT2 PPP3CC ZNF839	2.18e-04	195	141	7	2956_DN
Drug	Pancuronium bromide [15500-66-0]; Down 200; 5.4uM; MCF7; HT_HG-U133A	ABCA1 KDM5A GABBR2 MGAT2 PI4KB EDRF1 PLXNA2	2.18e-04	195	141	7	4393_DN
Drug	Meclozine dihydrochloride [1104-22-9]; Down 200; 8.6uM; PC3; HT_HG-U133A	ABCA1 ZC3H12A UBE3B THBS1 NUP210 PRKDC KLHDC10	2.18e-04	195	141	7	4646_DN
Drug	colchicine; Down 200; 1uM; SKMEL5; HG-U133A	THEMIS2 U2AF2 RAB14 MGAT2 PARD3 EDRF1 SEC23A	2.18e-04	195	141	7	630_DN
Drug	vinclozolin	TCF20 ACACA CYP19A1 DNMT3A	2.22e-04	48	141	4	CID000039676
Drug	C14800	CYP1A2 CYP2D7 CYP19A1 GSTT1	2.22e-04	48	141	4	CID011954051
Drug	Meclofenamic acid sodium salt monohydrate [6385-02-0]; Up 200; 11.8uM; HL60; HG-U133A	FLOT2 ABCA1 ZC3H12A GCKR RAB14 THBS1 SEC23A	2.25e-04	196	141	7	1445_UP
Drug	Diclofenac sodium [15307-79-6]; Down 200; 12.6uM; PC3; HT_HG-U133A	SASH1 KDM5A ATP13A2 TENM4 PPP3CC PCCA SEC23A	2.25e-04	196	141	7	5861_DN
Drug	Methylprednisolone, 6-alpha [83-43-2]; Up 200; 10.6uM; PC3; HT_HG-U133A	ZC3H12A IKZF1 THBS1 PDE8B NUP210 PCCA EPHA7	2.25e-04	196	141	7	7137_UP
Drug	16, 16-dimethylprostaglandin E2 methyl acetate solution; Down 200; 10uM; PC3; HT_HG-U133A	ATP13A2 RAB3GAP1 TENM4 PI4KB NUP210 PRKDC SEC23A	2.25e-04	196	141	7	6562_DN
Drug	Labetalol hydrochloride [32780-64-6]; Up 200; 11uM; PC3; HT_HG-U133A	ABCA1 FLT4 GALNT3 KDM5A GRK4 DGKQ PLXNC1	2.25e-04	196	141	7	4473_UP
Drug	formestane	CYP19A1 HSD17B1	2.27e-04	4	141	2	ctd:C014594
Drug	tetrabutyltin	CYP19A1 HSD17B1	2.27e-04	4	141	2	ctd:C102881
Drug	thiacloprid	CYP1A2 CYP19A1	2.27e-04	4	141	2	ctd:C417209
Drug	Heptaminol hydrochloride [543-15-7]; Up 200; 22uM; PC3; HT_HG-U133A	CYP1A2 ABCA1 PHF20 U2AF2 ZFYVE9 KLHDC10 SEC23A	2.32e-04	197	141	7	1825_UP
Drug	Pantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; PC3; HT_HG-U133A	CYP1A2 PHF20 UBE3B THBS1 TENM3 PDE8B CNN1	2.32e-04	197	141	7	4189_DN
Drug	Vancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; MCF7; HT_HG-U133A	MEX3D GABBR2 PTGS1 RHAG THBS1 ZFYVE9 PDE8B	2.32e-04	197	141	7	2858_UP
Drug	Prochlorperazine dimaleate [84-02-6]; Up 200; 6.6uM; MCF7; HT_HG-U133A	KDM5A DGKQ RAB14 MGAT2 PLXNC1 EDRF1 PLXNA2	2.32e-04	197	141	7	2641_UP
Drug	Bergenin monohydrate [477-90-7]; Down 200; 11.6uM; MCF7; HT_HG-U133A	CYP1A2 FLOT2 IKZF1 ARHGEF10L THBS1 TRABD NUP210	2.32e-04	197	141	7	3467_DN
Drug	Praziquantel [55268-74-1]; Down 200; 12.8uM; HL60; HG-U133A	THEMIS2 ACACA NOL6 LDB1 CIZ1 DCLRE1A KLHDC10	2.39e-04	198	141	7	1572_DN
Drug	Amiodarone hydrochloride [19774-82-4]; Down 200; 5.8uM; MCF7; HT_HG-U133A	PHF20 PTGS1 ZFYVE9 NUP210 CIZ1 HSD17B1 DNMT3A	2.39e-04	198	141	7	5253_DN
Drug	Bisoprolol fumarate; Down 200; 9uM; HL60; HT_HG-U133A	ZC3H12A DHX38 IKZF1 ARHGEF10L NUP210 CIZ1 KATNIP	2.39e-04	198	141	7	1287_DN
Drug	Fluocinonide [356-12-7]; Down 200; 8uM; MCF7; HT_HG-U133A	FLOT2 FLT4 PHF20 U2AF2 TRABD CIZ1 PARD3	2.39e-04	198	141	7	3839_DN
Drug	Lisuride (S)(-) [18016-80-3]; Up 200; 11.8uM; PC3; HG-U133A	ATP6V1A ATP13A2 RAB3GAP1 LDB1 CIZ1 PARD3 KLHDC10	2.39e-04	198	141	7	1962_UP
Drug	oxaloacetate	ACACA EHD2 CKM GOT1L1 DLD PCCA SORD	2.39e-04	198	141	7	CID000000970
Drug	19-HETE	CYP1A2 CYP2D7 CYP19A1 PTGS1	2.41e-04	49	141	4	CID006439528
Drug	bromobenzene-3,4-oxide	CYP1A2 CYP2D7 CYP19A1 GSTT1	2.41e-04	49	141	4	CID000108121
Drug	Cefalonium [5575-21-3]; Down 200; 8.8uM; HL60; HT_HG-U133A	THEMIS2 KDM5A UBE3B IKZF1 NUP210 KLHDC10 EDRF1	2.47e-04	199	141	7	2921_DN
Drug	Piretanide [55837-27-9]; Up 200; 11uM; MCF7; HT_HG-U133A	KIF21B ADCY2 PTGS1 EHD2 CKM PLXNC1 DNMT3A	2.47e-04	199	141	7	6828_UP
Drug	celecoxib; Down 200; 10uM; MCF7; HG-U133A	GALNT3 GABBR2 ATP13A2 EHD2 DCLRE1A PARD3 KLHDC10	2.47e-04	199	141	7	206_DN
Drug	Metixene hydrochloride [1553-34-0]; Down 200; 11.6uM; PC3; HT_HG-U133A	NOL6 GABBR2 ARHGEF10L TENM4 PLXNC1 NUP210 ZNF839	2.47e-04	199	141	7	6672_DN
Drug	Lisuride (S)(-) [18016-80-3]; Down 200; 11.8uM; HL60; HG-U133A	ZC3H12A SASH1 DHX38 CR1 ZFYVE9 CIZ1 ZNF839	2.47e-04	199	141	7	2046_DN
Drug	carnitine	CYP1A2 ACACA ACADL SLC7A7 CKM SLC22A4 DLD PCCA	2.53e-04	265	141	8	CID000000085
Drug	beta-naphthoflavone	CYP1A2 CYP2D7 CYP19A1 GSTT1 DLD RHOF SORD	2.55e-04	200	141	7	CID000002361
Drug	Tolmetin sodium salt dihydrate [64490-92-2]; Down 200; 12.6uM; PC3; HT_HG-U133A	CRMP1 TENM4 LDB1 PDE8B CNN1 EDRF1 PLXNA2	2.55e-04	200	141	7	4088_DN
Drug	trifluoperazine dihydrochloride; Down 200; 10uM; HL60; HT_HG-U133A	FLOT2 IKZF1 THBS1 LDB1 PI4KB KATNIP ZNF839	2.55e-04	200	141	7	1165_DN
Drug	Hesperidin [520-26-3]; Up 200; 6.6uM; MCF7; HT_HG-U133A	KDM5A PTGS1 THBS1 TENM3 PI4KB DYRK1B PARD3	2.55e-04	200	141	7	2648_UP
Drug	Methimazole [60-56-0]; Down 200; 35uM; MCF7; HT_HG-U133A	SASH1 ATP13A2 ARHGEF10L PI4KB NUP210 HSD17B1 KLHDC10	2.55e-04	200	141	7	3432_DN
Disease	isthmus cingulate cortex volume measurement	CYP2D7 TCF20 PTCHD3 SEPSECS TENM4	1.18e-07	26	136	5	EFO_0010310
Disease	prothrombin fragments F1+2 measurement	KIF26B RHAG	6.31e-05	3	136	2	EFO_0007776
Disease	neutrophil count, basophil count	THEMIS2 PCDHA13 IKZF1 GCKR JAML SLC22A4 PXYLP1	8.43e-05	224	136	7	EFO_0004833, EFO_0005090
Disease	L2 Acute Lymphoblastic Leukemia	CYP1A2 IKZF2 IKZF1 PRDM14	8.43e-05	50	136	4	C0023453
Disease	Childhood Acute Lymphoblastic Leukemia	CYP1A2 IKZF2 IKZF1 PRDM14	9.84e-05	52	136	4	C0023452
Disease	Metastatic melanoma	FLT4 DYRK1B PRKDC EPHA7	1.14e-04	54	136	4	C0278883
Disease	Clear-cell metastatic renal cell carcinoma	FLT4 DNMT3A	1.26e-04	4	136	2	C2931852
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	CYP1A2 IKZF2 IKZF1 PRDM14	1.84e-04	61	136	4	C1961102
Disease	Acute monocytic leukemia	FANCL BRCA1 DNMT3A	2.30e-04	26	136	3	C0023465
Disease	severe acute respiratory syndrome, COVID-19	DLGAP2 RELN IKZF2 GRK4 CRMP1 SEPSECS NUP210 PARD3 EPHA7	2.38e-04	447	136	9	EFO_0000694, MONDO_0100096
Disease	stomach cancer (is_implicated_in)	ERCC5 GSTT1 BRCA1 DNMT3A	3.48e-04	72	136	4	DOID:10534 (is_implicated_in)
Disease	phosphatidylcholine measurement	DLGAP2 ABCA1 GCKR OSBP PPT2 SLC22A4 UNC5D	3.61e-04	284	136	7	EFO_0010226
Disease	neuroimaging measurement	KIF21B CYP1A2 RELN SZT2 KIF26B ATP13A2 CRMP1 TYK2 THBS1 BRCA1 PKHD1 PARD3 PCCA PLXNA2	4.33e-04	1069	136	14	EFO_0004346
Disease	smoking status measurement, Crohn's disease	BTNL2 DNMT3A	4.36e-04	7	136	2	EFO_0000384, EFO_0006527
Disease	brain connectivity measurement	CYP2D7 KIF26B ARL17A THBS1 TENM4 PCCA PLXNA2 EPHA7	5.54e-04	400	136	8	EFO_0005210
Disease	clostridium difficile infection	DLGAP2 IKZF1 LRBA DDX39B EPHA7	5.57e-04	144	136	5	EFO_0009130
Disease	pantothenate measurement	ABCA1 ACOD1	5.80e-04	8	136	2	EFO_0021034
Disease	response to tamoxifen	CYP2D7 TCF20	7.43e-04	9	136	2	EFO_0009391
Disease	Schizophrenia	CYP1A2 DLGAP2 RELN ABCA1 PTGS1 CRMP1 GSTT1 THBS1 TENM4 PPP3CC BRCA1 PLXNA2	8.18e-04	883	136	12	C0036341
Disease	multiple system atrophy	PYROXD2 PKHD1L1 SORD	8.35e-04	40	136	3	EFO_1001050
Disease	Asthma, Occupational	PTGS1 TENM3	9.26e-04	10	136	2	C0264423
Disease	Fanconi anemia (is_implicated_in)	GSTT1 BRCA1	9.26e-04	10	136	2	DOID:13636 (is_implicated_in)
Disease	DNA methylation	DNHD1 ABCA1 IKZF2 SASH1 GCKR TENM4 TENM3 PKHD1 PARD3 ZNF839	9.54e-04	656	136	10	GO_0006306
Disease	triglycerides in large LDL measurement	ABCA1 GCKR HPR	1.03e-03	43	136	3	EFO_0022319
Disease	diet measurement	CYP1A2 DLGAP2 TCF20 KIF26B FANCL GCKR TENM4 PKHD1 PRKDC PCCA UNC5D DNMT3A EPHA7	1.15e-03	1049	136	13	EFO_0008111
Disease	granulocyte count	THEMIS2 IKZF1 GCKR JAML SLC22A4 PXYLP1	1.19e-03	254	136	6	EFO_0007987
Disease	total lipids in lipoprotein particles measurement	ABCA1 DHX38 GCKR	1.42e-03	48	136	3	EFO_0022309
Disease	pyruvate measurement	DLGAP2 SASH1 PTCHD3 IKZF1 GCKR CR1	1.56e-03	268	136	6	EFO_0010117
Disease	Common variable immunodeficiency	IKZF1 LRBA	1.59e-03	13	136	2	cv:C0009447
Disease	Hypoxanthine measurement	ERCC5 PKHD1	1.59e-03	13	136	2	EFO_0021604
Disease	FVC change measurement, response to placebo	RELN KATNIP	1.59e-03	13	136	2	EFO_0008344, EFO_0010339
Disease	Crohn Disease	TYK2 SLC22A4 DNMT3A	1.60e-03	50	136	3	C0010346
Disease	total lipids in LDL measurement	ABCA1 GCKR HPR	1.79e-03	52	136	3	EFO_0022308
Disease	neuronal ceroid lipofuscinosis (implicated_via_orthology)	ATP13A2 PPT2	1.85e-03	14	136	2	DOID:14503 (implicated_via_orthology)
Disease	cortical thickness	FLOT2 RELN ATP13A2 CRMP1 THBS1 SEPSECS KIAA0825 PLXNC1 PKHD1 PARD3 PCCA PLXNA2 EPHA7	1.95e-03	1113	136	13	EFO_0004840
Disease	sex interaction measurement, inflammatory bowel disease	IKZF1 GCKR BTNL2	2.11e-03	55	136	3	EFO_0003767, EFO_0008343
Disease	acute lymphoblastic leukemia (is_implicated_in)	IKZF1 GSTT1 DNMT3A	2.11e-03	55	136	3	DOID:9952 (is_implicated_in)
Disease	lysophosphatidylcholine 14:0 measurement	GCKR ACOD1	2.13e-03	15	136	2	EFO_0010356
Disease	alcohol use disorder (implicated_via_orthology)	KDM5A GRK4 RHBDL1 KCNU1 CIZ1	2.14e-03	195	136	5	DOID:1574 (implicated_via_orthology)
Disease	triglycerides in LDL measurement	ABCA1 GCKR HPR	2.22e-03	56	136	3	EFO_0022320
Disease	ferritin measurement	DHX38 GCKR MYO3A TENM3	2.28e-03	119	136	4	EFO_0004459
Disease	Prostatic Neoplasms	GALNT3 CYP19A1 EI24 GSTT1 BRCA1 CIZ1 PRKDC HSD17B1 PARD3	2.28e-03	616	136	9	C0033578
Disease	Malignant neoplasm of prostate	GALNT3 CYP19A1 EI24 GSTT1 BRCA1 CIZ1 PRKDC HSD17B1 PARD3	2.28e-03	616	136	9	C0376358
Disease	total lipids in large LDL	ABCA1 GCKR HPR	2.34e-03	57	136	3	EFO_0022163
Disease	cholesterol in large LDL measurement	ABCA1 GCKR HPR	2.34e-03	57	136	3	EFO_0021901
Disease	syndromic intellectual disability (implicated_via_orthology)	KDM5A DYRK1B	2.43e-03	16	136	2	DOID:0050888 (implicated_via_orthology)
Disease	coffee consumption, cups of coffee per day measurement	CYP1A2 GCKR	2.43e-03	16	136	2	EFO_0004330, EFO_0006782
Disease	rheumatoid arthritis (is_implicated_in)	GSTT1 BTNL2 SLC22A4	2.46e-03	58	136	3	DOID:7148 (is_implicated_in)
Disease	insulin resistance	SLC30A8 GCKR KCNU1	2.58e-03	59	136	3	EFO_0002614
Disease	alkaline phosphatase measurement	MACC1 GALNT3 CYP19A1 DHX38 ADAMTS13 GCKR CRMP1 MYO3A ATRIP BTNL2 MYMK LRBA	2.63e-03	1015	136	12	EFO_0004533
Disease	Sjogren syndrome	RELN DGKQ PDE8B	2.71e-03	60	136	3	EFO_0000699
Disease	Sjogren's syndrome (implicated_via_orthology)	CYP19A1 THBS1	2.74e-03	17	136	2	DOID:12894 (implicated_via_orthology)
Disease	ulcerative colitis (is_implicated_in)	GSTT1 BTNL2	2.74e-03	17	136	2	DOID:8577 (is_implicated_in)
Disease	t-tau measurement	DLGAP2 PTCHD3 ARL17A PARD3	2.80e-03	126	136	4	EFO_0004760
Disease	esterified cholesterol measurement	ABCA1 DHX38 GCKR HPR	2.96e-03	128	136	4	EFO_0008589
Disease	triglycerides in medium LDL measurement	ABCA1 GCKR HPR	2.97e-03	62	136	3	EFO_0022322
Disease	Child Behaviour Checklist assessment	TENM4 TENM3	3.07e-03	18	136	2	EFO_0005661
Disease	neutrophil count, eosinophil count	IKZF1 GCKR JAML SLC22A4 PXYLP1	3.13e-03	213	136	5	EFO_0004833, EFO_0004842
Disease	alcohol use disorder measurement	TCF20 GRK4 GCKR GABBR2 PKHD1	3.20e-03	214	136	5	EFO_0009458
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	ACACA ADAMTS13 HPR	3.40e-03	65	136	3	DOID:0080208 (biomarker_via_orthology)
Disease	bitter alcoholic beverage consumption measurement	RELN GCKR ANKRD36 PLXNA2	3.40e-03	133	136	4	EFO_0010092
Disease	primary biliary cirrhosis	KIF21B DGKQ TYK2 DNMT3A	3.40e-03	133	136	4	EFO_1001486
Disease	prion disease	ATRIP PXYLP1	3.43e-03	19	136	2	EFO_0004720
Disease	bipolar disorder (is_marker_for)	RELN PTGS1	3.43e-03	19	136	2	DOID:3312 (is_marker_for)
Disease	Cholecystitis	GCKR LRBA	3.43e-03	19	136	2	HP_0001082
Disease	type 1 diabetes mellitus (biomarker_via_orthology)	GSTT1 HPR	3.43e-03	19	136	2	DOID:9744 (biomarker_via_orthology)
Disease	caffeine metabolite measurement	CYP1A2 GCKR	3.43e-03	19	136	2	EFO_0007872
Disease	colorectal cancer, inflammatory bowel disease	DLGAP2 PTCHD3	3.43e-03	19	136	2	EFO_0003767, MONDO_0005575
Disease	polymyositis	UBE3B DGKQ	3.79e-03	20	136	2	EFO_0003063
Disease	HbA1c measurement	FLOT2 SLC30A8 ADAMTS13 GCKR SLC7A7 RHAG ATRIP PXYLP1 UNC5D	4.16e-03	675	136	9	EFO_0004541
Disease	haptoglobin measurement	DHX38 HPR	4.18e-03	21	136	2	EFO_0004640
Disease	sex interaction measurement, COVID-19	MACC1 EPHA7	4.18e-03	21	136	2	EFO_0008343, MONDO_0100096
Disease	esophagus adenocarcinoma (is_implicated_in)	CYP19A1 GSTT1	4.18e-03	21	136	2	DOID:4914 (is_implicated_in)
Disease	Manic Disorder	RELN ADCY2 TENM4	4.35e-03	71	136	3	C0024713
Disease	childhood trauma measurement, alcohol consumption measurement	DLGAP2 PCDHGC5 GABBR2	4.35e-03	71	136	3	EFO_0007878, EFO_0007979
Disease	serum metabolite measurement	CYP1A2 CFAP251 ACADL KIF26B DHX38 PYROXD2 OR52L1 GCKR TENM3 SLC22A4 EPHA7	4.43e-03	945	136	11	EFO_0005653
Disease	Seckel syndrome	ATRIP DNMT3A	4.59e-03	22	136	2	C0265202
Disease	fat intake measurement	NOL6 DNMT3A	4.59e-03	22	136	2	EFO_0010809

Protein segments in the cluster

Peptide	Gene	Start	Entry
GISQEVIQHMPVSCA	C2orf16	1006	Q68DN1
GHINPAVSLAMCLFG	AQP9	81	O43315
PILAMAGGHVELQCQ	BTNL10	41	A8MVZ5
QRFCIGHPTQEMTFG	CCDC17	31	Q96LX7
MVSLNGHCGPVAFLA	ARHGEF10L	1106	Q9HCE6
LPIGLVFHTMVTCGG	CCIN	361	Q13939
NVTLEHPLFVGGMCQ	DNMT3A	501	Q9Y6K1
HFIPQMTAGKCIGAI	ACADL	156	P28330
HMEGPGESGVQLVCT	BTNL2	151	Q9UIR0
VQHECIPQAILGMDV	DDX39B	71	Q13838
VVEQIPHGCVLVMGN	GOT1L1	171	Q8NHS2
CFVAVMHGDTEGTVP	EHD2	96	Q9NZN4
MGNCHTVGPNEALVV	FLOT2	1	Q14254
GVCPQHNVLFDMLTV	ABCA1	976	O95477
PESFQLVEVAMGCRH	DGKQ	441	P52824
PDTMLGVVCGALHVA	ACACA	626	Q13085
MGTAQVLPGILQKHC	DLGAP2	1	Q9P1A6
SGVLPIKCSHVEFGM	ARL17A	101	Q8IVW1
LACATGQPEMVHLLV	ANKRD36	71	A6QL64
HVPCVENMIQTLTGG	DNHD1	571	Q96M86
GPNEVLLRMHSVGIC	SORD	31	Q00796
CQVHGFPKIMGVLTH	BMS1	171	Q14692
CILVEMHTGEPLFSG	DYRK1B	301	Q9Y463
ACGRQHLEPTGTIDM	ADAMTS13	1191	Q76LX8
VHTIFDSCPEGNGIM	CFAP251	336	Q8TBY9
AIVCHPNGVAGMAVS	CFAP251	886	Q8TBY9
PVDVACGVDHMVTLA	RCC1L	446	Q96I51
FMADCPHTIGVEFGT	RAB14	36	P61106
CQGPGVRTDFEMVHL	RAB3GAP1	181	Q15042
VANVIGAMCFGQHFP	CYP1A2	196	P05177
LACATGQPEMVHLLV	ANKRD36C	71	Q5JPF3
MPGHLQEGFGCVVTN	SERBP1	1	Q8NC51
HSMEFAPCQVEARVG	NUP210	536	Q8TEM1
LPMAHCVVTAIEGFS	KIAA0825	426	Q8IV33
TQHGKPMFTQVCVEG	LDB1	166	Q86U70
VPQIPRIFHAGDCGM	MGAT2	366	Q10469
NVPELVMCFHVNGIV	EDRF1	361	Q3B7T1
GVQPILNEHTFCVGM	HPR	271	P00739
AMVSHLVGGILPTCE	KATNIP	1531	O60303
QTCFGHGEAMAEPVA	KIF26B	1301	Q2KJY2
NIFEGMVCHGVPLVT	DPYS	426	Q14117
CEMGHALVGTTSGPV	PLXNA2	916	O75051
PHIDGCLSVIAQAFM	PLXNC1	1436	O60486
VTPAGCMYIHGGVVN	KLHDC10	371	Q6PID8
CGFLMVVAGILGFVH	OR4C45	136	A6NMZ5
CGGFIHSIMQVILVI	OR4Q3	151	Q8NH05
GQPAMEGHCVIQVDV	PCDHGC5	326	Q9Y5F6
MGCAPSIHVSQSGVI	PDE8B	1	O95263
GHIGPVMCLTVTQTA	KIF21B	1451	O75037
YVEPMTVVCHLEGSG	NOL6	731	Q9H6R4
GEVMAALVPCGHNLF	MEX3D	606	Q86XN8
AMHSIGGVQVLFPLF	LRBA	466	P50851
IVACVFGDAHSAPMG	KCNU1	716	A8MYU2
ICGIICIGPNVLMVH	IKZF1	121	Q13422
VVFIGPDTHAIQAMG	PCCA	161	P05165
CHPNSIFGESMIEIG	PTGS1	511	P23219
CEASIMGQFDHPNVV	EPHA7	681	Q15375
VCGMVCIGPNVLMVH	IKZF2	116	Q9UKS7
IMPLGTIHCIFHATG	OSBP	556	P22059
FHQVCVGVSPEMAEN	KDM5A	1636	P29375
CGAIMHGNAVTFCEP	RELN	231	P78509
MIQFSINLGCGTHQP	RELN	571	P78509
GNIPMAGHCTLLVEV	PCDHA13	326	Q9Y5I0
IAIMDGVECIHTFGA	GCKR	341	Q14397
GAIVRCPMAGISHTA	PPT2	271	Q9UMR5
FHAIGQMCEAPVVTR	BRCA1	1821	P38398
CSPGELVHMLNELFG	ADCY2	306	Q08462
ARGCGMVAPQEHLII	ATP13A2	761	Q9NQ11
FAMAALLGGVHQCPL	HEATR5B	506	Q9P2D3
TISIQEHMAIDVCPG	DOC2B	11	Q14184
PGFVMVGSHTVQCQT	CR1	1621	P17927
GLQCIGMHEKGIIFN	CYP19A1	121	P11511
IVCVGGDGMFSEVLH	CERK	191	Q8TCT0
CGGQLEIMPCSVVGH	GALNT3	401	Q14435
CGPVHTAFMEKVLGS	HSD17B1	186	P14061
IQGMFVSLFPIHLVG	EI24	186	O14681
IICVEGMAGGAVHID	DLD	371	P09622
VVLTVCGHNYMPGQL	MACC1	386	Q6ZN28
GFMDVVCIGLIIHEG	MARCHF4	281	Q9P2E8
NHLMVFGGVCPSVTS	GABBR2	126	O75899
MLLDGGITVPSFHEC	ACOD1	341	A6NK06
VVLLDANHCPGAVMI	DCLRE1A	786	Q6PJP8
CVEVLHQFDQVMPGV	ATRIP	741	Q8WXE1
FMLQQIEEPCSLGVH	DGKZ	221	Q13574
GQESVHCGPMFIQVS	C1orf127	11	Q8N9H9
GLGCLIYEMIQGHSP	GRK4	371	P32298
GMCLEVLGVQPTAHE	B3GNT7	331	Q8NFL0
EDPVSCAFVVLMAHG	CASP14	76	P31944
GMSVVFLAGTPEHRC	SLC22A4	36	Q9H015
DVMCSFVPHQLGVFK	CFAP47	471	Q6ZTR5
GEFVNVFCHGSLVMQ	DDB1	1001	Q16531
GMECHGSPLVVISQG	CRMP1	436	Q14194
VMIFGAAHGLIFIPV	PTCHD3	931	Q3KNS1
RVVVPCGDGHMKVFS	PARD3	11	Q8TEW0
QHGVCMGLLEENVPE	PHF20	676	Q9BVI0
STILHPGVIGCIGMV	OR52L1	151	Q8NGH7
ITELMHPVGAGCQVF	GSTT1	171	P30711
FHFACSGEGIINMVL	SZT2	831	Q5T011
VALAGHTGEFMCLVV	STK11IP	816	Q8N1F8
EVTHFCRGIPMVLIG	RHOF	116	Q9HBH0
EGLCLMQTVFGEVPH	PRDM14	251	Q9GZV8
MQTVFGEVPHFGVFC	PRDM14	256	Q9GZV8
TMLPECFFLGADHVV	FANCL	246	Q9NW38
VDNPGHPFIMTVGCV	CKM	61	P06732
HPFIMTVGCVAGDEE	CKM	66	P06732
HVGGLIQMGCVFQST	JAML	146	Q86YT9
AIQAALPGICHMAFV	PKDREJ	2081	Q9NTG1
CVTAMEILNEFPGHG	ERCC5	871	P28715
MFHLGVPTTRAGACV	SELENOO	206	Q9BVL4
NHPLCEMGELTQTGV	PXYLP1	156	Q8TE99
VFCDRMNGIHIDPGT	PKHD1	2836	P08F94
VEIMQQGSQLPCFHG	PI4KB	751	Q9UBF8
HALFQPCDGEMIIVL	SUPT16H	706	Q9Y5B9
QPSFMAHLAGAVVGV	RHBDL1	371	O75783
LITFGRMVQVHELGC	SEC23A	166	Q15436
VVVHVCGLEMPPDAV	CIZ1	481	Q9ULV3
RQIFEPGLGMEHCDT	CNN1	226	P51911
MPCTTAVIHEVQHFG	CYP2D7	371	A0A087X1C5
ITVCGDIHGQFFDLM	PPP3CC	81	P48454
CFIFMIAEVVGGHIA	SLC30A8	81	Q8IWU4
FLMHVCGTNRIPESG	THBS1	11	P07996
PGTHLLAVGFAECML	WDR90	1686	Q96KV7
CGVFPPHLVEAVMGR	ZC3H12A	561	Q5D1E8
PGGNIFHCAMSLDQL	PYROXD2	516	Q8N2H3
KCVPSVVVGVVGMGH	TRABD	286	Q9H4I3
FVGSREGHLPDAICM	SLC7A7	336	Q9UM01
CVLGMEGQQVILHLP	THEMIS2	146	Q5TEJ8
EMQCLVAGAHAPSIV	FLT4	696	P35916
GIIEVENMAHCEFPL	SEPTIN12	271	Q8IYM1
VAVGTCADMAIHPFG	RHAG	281	Q02094
FDGGHACVIRGQVMT	TENM4	916	Q6N022
QHRMAIPSGGLTEIC	SASH1	1156	O94885
IAAGRPMHCQVPGVE	TENM3	1376	Q9P273
VHGVSGPVVTACDMA	ATP6V1A	21	P38606
GIGEYVNIRTGMPCH	DHX38	1086	Q92620
VSSAGVKVLMGHFPC	PKHD1L1	1686	Q86WI1
QCIVGDHAGGTFPVM	PKHD1L1	1966	Q86WI1
GPVVTESSVMGHLVC	TCF20	1691	Q9UGU0
QGREVPIEGMIVLHC	UNC5D	166	Q6UXZ4
IGDVQVMAHLPDVCV	PRKDC	1386	P78527
FPCGMEVHSGQRELE	ZNF839	731	A8K0R7
EDVMGQLVCHELIPG	UBE3B	851	Q7Z3V4
SQVQMGGHPTEVLCL	U2AF2	366	P26368
GGHPTEVLCLMNMVL	U2AF2	371	P26368
VHTVANCFVVPMATG	SEPSECS	131	Q9HD40
HGGACQLSEGPVVME	ZFYVE9	1401	O95405
HCKSGPMTGVVLVAV	SIGLEC16	426	A6NMB1
AFVHGVCVRGPENIM	TYK2	671	P29597
NGPGLSVLCFMRHDI	MYMK	51	A6NI61
LTEFIGIHQCMGGTE	MYO3A	301	Q8NEV4