Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmalate dehydrogenase (decarboxylating) (NADP+) activity

ME1 ME2 ME3

1.87e-083543GO:0004473
GeneOntologyMolecularFunctionmalic enzyme activity

ME1 ME2 ME3

7.46e-084543GO:0004470
GeneOntologyMolecularFunctionoxaloacetate decarboxylase activity

ME1 ME2 ME3

7.46e-084543GO:0008948
GeneOntologyMolecularFunctiongalactose transmembrane transporter activity

SLC2A14 SLC2A3 SLC5A1

3.72e-076543GO:0005354
GeneOntologyMolecularFunctionD-glucose transmembrane transporter activity

SLC2A14 SLC2A3 SLC5A1 SLC5A2

5.79e-0725544GO:0055056
GeneOntologyMolecularFunctionhexose transmembrane transporter activity

SLC2A14 SLC2A3 SLC5A1 SLC5A2

5.79e-0725544GO:0015149
GeneOntologyMolecularFunctionmonosaccharide transmembrane transporter activity

SLC2A14 SLC2A3 SLC5A1 SLC5A2

8.00e-0727544GO:0015145
GeneOntologyMolecularFunctionmalate dehydrogenase activity

ME1 ME2 ME3

1.04e-068543GO:0016615
GeneOntologyMolecularFunctionsugar transmembrane transporter activity

SLC2A14 SLC2A3 SLC5A1 SLC5A2

1.08e-0629544GO:0051119
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

SLC2A14 SLC2A3 SLC5A1 SLC5A2

4.95e-0642544GO:0015144
GeneOntologyMolecularFunctionmalate dehydrogenase (decarboxylating) (NAD+) activity

ME1 ME2

7.18e-062542GO:0004471
GeneOntologyMolecularFunctionalpha-glucoside transmembrane transporter activity

SLC5A1 SLC5A2

7.18e-062542GO:0015151
GeneOntologyMolecularFunctionxylose binding

SLC2A14 SLC2A3

7.18e-062542GO:0033222
GeneOntologyMolecularFunctionglucoside transmembrane transporter activity

SLC5A1 SLC5A2

2.15e-053542GO:0042947
GeneOntologyMolecularFunctionnatriuretic peptide receptor activity

NPR1 NPR2

2.15e-053542GO:0016941
GeneOntologyMolecularFunctionsmall conductance calcium-activated potassium channel activity

KCNN1 KCNN3

4.29e-054542GO:0016286
GeneOntologyMolecularFunctioncarboxy-lyase activity

ME1 ME2 ME3

1.25e-0436543GO:0016831
GeneOntologyMolecularFunctionD-glucose:sodium symporter activity

SLC5A1 SLC5A2

1.49e-047542GO:0005412
GeneOntologyMolecularFunctiondehydroascorbic acid transmembrane transporter activity

SLC2A14 SLC2A3

1.99e-048542GO:0033300
GeneOntologyMolecularFunctiongalactoside binding

SLC2A14 SLC2A3

2.55e-049542GO:0016936
GeneOntologyMolecularFunctionlyase activity

NPR1 NPR2 ME1 ME2 ME3

2.67e-04212545GO:0016829
GeneOntologyMolecularFunctionguanylate cyclase activity

NPR1 NPR2

3.19e-0410542GO:0004383
GeneOntologyMolecularFunctioncarbon-carbon lyase activity

ME1 ME2 ME3

4.68e-0456543GO:0016830
GeneOntologyMolecularFunctionD-glucose binding

SLC2A14 SLC2A3

6.40e-0414542GO:0005536
GeneOntologyMolecularFunctioncalcium-activated potassium channel activity

KCNN1 KCNN3

6.40e-0414542GO:0015269
GeneOntologyMolecularFunctioncarbohydrate:monoatomic cation symporter activity

SLC5A1 SLC5A2

9.51e-0417542GO:0005402
GeneOntologyMolecularFunctionNAD binding

ME1 ME2 ME3

1.02e-0373543GO:0051287
GeneOntologyMolecularFunctionadenylate cyclase activity

NPR1 NPR2

1.07e-0318542GO:0004016
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC4A9 SLC5A1 SLC5A2

1.37e-0381543GO:0015370
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

KCNN1 KCNN3 KCNK7 SLC4A9 SLC5A1 SLC5A2

1.55e-03465546GO:0046873
GeneOntologyMolecularFunctioncyclase activity

NPR1 NPR2

1.91e-0324542GO:0009975
GeneOntologyMolecularFunctionphosphorus-oxygen lyase activity

NPR1 NPR2

2.07e-0325542GO:0016849
GeneOntologyMolecularFunctioncalcium-activated cation channel activity

KCNN1 KCNN3

2.41e-0327542GO:0005227
GeneOntologyMolecularFunctioninward rectifier potassium channel activity

KCNN1 KCNN3

2.59e-0328542GO:0005242
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity

KCNN1 KCNN3 KCNK7

2.66e-03102543GO:0005249
GeneOntologyMolecularFunctionmonoatomic ion-gated channel activity

KCNN1 KCNN3

3.17e-0331542GO:0022839
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLCO1A2 SLC2A14 KCNN1 KCNN3 KCNK7 SLC4A9 SLC2A3 SLC5A1 SLC5A2

4.09e-031180549GO:0022857
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC4A9 SLC5A1 SLC5A2

4.10e-03119543GO:0015294
GeneOntologyMolecularFunctionvitamin transmembrane transporter activity

SLC2A14 SLC2A3

4.26e-0336542GO:0090482
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

ME1 ME2 ME3

4.92e-03127543GO:0016616
GeneOntologyMolecularFunctionpotassium channel activity

KCNN1 KCNN3 KCNK7

5.03e-03128543GO:0005267
GeneOntologyMolecularFunctionprotein kinase activity

NPR1 NPR2 PIK3CA CAMK4 CSNK1G3 MUSK

5.46e-03600546GO:0004672
GeneOntologyMolecularFunctionDNA secondary structure binding

MSH6 SMC5

5.50e-0341542GO:0000217
GeneOntologyMolecularFunctionglycosaminoglycan binding

STAB2 FBN1 TENM1 VEGFA

5.93e-03268544GO:0005539
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH-OH group of donors

ME1 ME2 ME3

6.19e-03138543GO:0016614
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

KCNN1 KCNN3 KCNK7 SLC4A9 SLC5A1 SLC5A2

6.73e-03627546GO:0022890
GeneOntologyMolecularFunctiontransporter activity

SLCO1A2 SLC2A14 KCNN1 KCNN3 KCNK7 SLC4A9 SLC2A3 SLC5A1 SLC5A2

7.23e-031289549GO:0005215
GeneOntologyMolecularFunctionADP binding

MSH6 ME1

7.48e-0348542GO:0043531
GeneOntologyMolecularFunctionsymporter activity

SLC4A9 SLC5A1 SLC5A2

7.79e-03150543GO:0015293
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

KCNN1 KCNN3 KCNK7

8.08e-03152543GO:0022843
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLCO1A2 SLC2A14 SLC4A9 SLC2A3

8.08e-03293544GO:0008514
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLCO1A2 SLC4A9 SLC5A1 SLC5A2

8.37e-03296544GO:0015291
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

KCNN1 KCNN3 KCNK7 SLC4A9 SLC5A1 SLC5A2

8.81e-03664546GO:0008324
GeneOntologyMolecularFunctionpeptide hormone binding

NPR1 NPR2

9.73e-0355542GO:0017046
GeneOntologyBiologicalProcessD-glucose import across plasma membrane

SLC2A3 SLC5A1 SLC5A2

1.60e-075533GO:0098708
GeneOntologyBiologicalProcesscarbohydrate import across plasma membrane

SLC2A3 SLC5A1 SLC5A2

3.19e-076533GO:0098704
GeneOntologyBiologicalProcesshexose import across plasma membrane

SLC2A3 SLC5A1 SLC5A2

3.19e-076533GO:0140271
GeneOntologyBiologicalProcessmalate metabolic process

ME1 ME2 ME3

1.33e-069533GO:0006108
GeneOntologyBiologicalProcessalpha-glucoside transport

SLC5A1 SLC5A2

6.48e-062532GO:0000017
GeneOntologyBiologicalProcessglucoside transport

SLC5A1 SLC5A2

1.94e-053532GO:0042946
GeneOntologyBiologicalProcessrenal D-glucose absorption

SLC5A1 SLC5A2

3.87e-054532GO:0035623
GeneOntologyBiologicalProcessglycoside transport

SLC5A1 SLC5A2

6.45e-055532GO:1901656
GeneOntologyBiologicalProcessgalactose transmembrane transport

SLC2A3 SLC5A1

9.65e-056532GO:0015757
GeneOntologyBiologicalProcessdehydroascorbic acid transport

SLC2A14 SLC2A3

2.31e-049532GO:0070837
GeneOntologyBiologicalProcesspositive regulation of cGMP-mediated signaling

NPR1 NPR2

2.31e-049532GO:0010753
GeneOntologyBiologicalProcessregulation of NADP metabolic process

ME1 ME2

2.88e-0410532GO:1902031
GeneOntologyBiologicalProcessdigestive system process

NPR2 SLCO1A2 SLC4A9 SLC5A1

3.08e-04126534GO:0022600
GeneOntologyBiologicalProcessangiogenesis

TSPAN12 NPR1 NPR2 STAB2 HDAC5 PIK3CA GATA4 VEGFA

4.19e-04708538GO:0001525
GeneOntologyBiologicalProcesscGMP biosynthetic process

NPR1 NPR2

4.21e-0412532GO:0006182
GeneOntologyBiologicalProcessreceptor guanylyl cyclase signaling pathway

NPR1 NPR2

4.21e-0412532GO:0007168
DomainMalic_OxRdtase

ME1 ME2 ME3

2.16e-083533IPR001891
DomainMalic_NAD-bd

ME1 ME2 ME3

2.16e-083533IPR012302
DomainMalic_N_dom

ME1 ME2 ME3

2.16e-083533IPR012301
DomainMALIC_ENZYMES

ME1 ME2 ME3

2.16e-083533PS00331
DomainMalic_M

ME1 ME2 ME3

2.16e-083533PF03949
DomainMalic_M

ME1 ME2 ME3

2.16e-083533SM00919
Domainmalic

ME1 ME2 ME3

2.16e-083533PF00390
Domain-

ME1 ME2 ME3

2.16e-0835333.40.50.10380
Domainmalic

ME1 ME2 ME3

2.16e-083533SM01274
DomainMalic_enzyme_CS

ME1 ME2 ME3

2.16e-083533IPR015884
DomainGlc_transpt_3

SLC2A14 SLC2A3

7.90e-062532IPR002945
DomainANF_RECEPTORS

NPR1 NPR2

2.37e-053532PS00458
DomainANPR/GUC

NPR1 NPR2

2.37e-053532IPR001170
DomainK_chnl_dom

KCNN1 KCNN3 KCNK7

2.77e-0521533IPR013099
DomainIon_trans_2

KCNN1 KCNN3 KCNK7

2.77e-0521533PF07885
DomainCaMBD

KCNN1 KCNN3

4.72e-054532PF02888
DomainCaM-bd_dom

KCNN1 KCNN3

4.72e-054532IPR004178
DomainCaMBD

KCNN1 KCNN3

4.72e-054532SM01053
DomainSK_channel

KCNN1 KCNN3

4.72e-054532PF03530
DomainK_chnl_Ca-activ_SK

KCNN1 KCNN3

4.72e-054532IPR015449
DomainANF_lig-bd_rcpt

NPR1 NPR2 GRM8

1.57e-0437533IPR001828
DomainANF_receptor

NPR1 NPR2 GRM8

1.57e-0437533PF01094
DomainPeripla_BP_I

NPR1 NPR2 GRM8

1.83e-0439533IPR028082
DomainNa/solute_symporter_CS

SLC5A1 SLC5A2

2.19e-048532IPR018212
Domain-

STAB2 HMCN1

4.27e-04115322.40.155.10
DomainNA_SOLUT_SYMP_1

SLC5A1 SLC5A2

4.27e-0411532PS00456
DomainGFP-like

STAB2 HMCN1

4.27e-0411532IPR023413
DomainNA_SOLUT_SYMP_2

SLC5A1 SLC5A2

5.12e-0412532PS00457
DomainSSF

SLC5A1 SLC5A2

5.12e-0412532PF00474
DomainNa/solute_symporter

SLC5A1 SLC5A2

5.12e-0412532IPR001734
DomainNA_SOLUT_SYMP_3

SLC5A1 SLC5A2

5.12e-0412532PS50283
DomainMFS_dom

SLCO1A2 SLC2A14 UNC93A SLC2A3

5.65e-04134534IPR020846
DomainSugar/inositol_transpt

SLC2A14 SLC2A3

7.03e-0414532IPR003663
DomainSUGAR_TRANSPORT_2

SLC2A14 SLC2A3

1.05e-0317532PS00217
DomainA/G_cyclase_CS

NPR1 NPR2

1.05e-0317532IPR018297
DomainNucleotide_cyclase

NPR1 NPR2

1.17e-0318532IPR029787
Domain-

NPR1 NPR2

1.17e-03185323.30.70.1230
DomainGUANYLATE_CYCLASE_1

NPR1 NPR2

1.31e-0319532PS00452
DomainGuanylate_cyc

NPR1 NPR2

1.31e-0319532PF00211
DomainGUANYLATE_CYCLASE_2

NPR1 NPR2

1.31e-0319532PS50125
DomainA/G_cyclase

NPR1 NPR2

1.31e-0319532IPR001054
DomainCYCc

NPR1 NPR2

1.31e-0319532SM00044
DomainGPCR_3

GPR158 GRM8

1.60e-0321532IPR000337
Domain7tm_3

GPR158 GRM8

1.76e-0322532PF00003
DomainG_PROTEIN_RECEP_F3_2

GPR158 GRM8

1.76e-0322532PS00980
DomainG_PROTEIN_RECEP_F3_3

GPR158 GRM8

1.76e-0322532PS00981
DomainG_PROTEIN_RECEP_F3_1

GPR158 GRM8

1.76e-0322532PS00979
DomainG_PROTEIN_RECEP_F3_4

GPR158 GRM8

1.76e-0322532PS50259
DomainGPCR_3_C

GPR158 GRM8

1.76e-0322532IPR017978
DomainSUGAR_TRANSPORT_1

SLC2A14 SLC2A3

2.10e-0324532PS00216
DomaincEGF

FBN1 HMCN1

2.46e-0326532IPR026823
DomaincEGF

FBN1 HMCN1

2.46e-0326532PF12662
DomainVWF_A

CPNE2 HMCN1 SEC23A

2.79e-0399533IPR002035
DomainMFS

SLCO1A2 SLC2A14 SLC2A3

3.57e-03108533PS50850
DomainSugar_transporter_CS

SLC2A14 SLC2A3

3.71e-0332532IPR005829
DomainKinase-like_dom

NPR1 NPR2 PIK3CA CAMK4 CSNK1G3 MUSK

4.20e-03542536IPR011009
DomainEGF_3

STAB2 FBN1 HMCN1 TENM1

4.42e-03235534PS50026
DomainEGF

STAB2 FBN1 HMCN1 TENM1

4.42e-03235534SM00181
DomainMFS_sugar_transport-like

SLC2A14 SLC2A3

4.68e-0336532IPR005828
DomainSugar_tr

SLC2A14 SLC2A3

4.68e-0336532PF00083
DomainEGF_CA

STAB2 FBN1 HMCN1

5.02e-03122533SM00179
DomainEGF-like_Ca-bd_dom

STAB2 FBN1 HMCN1

5.25e-03124533IPR001881
DomainEGF-like_dom

STAB2 FBN1 HMCN1 TENM1

5.41e-03249534IPR000742
DomainPkinase_Tyr

NPR1 NPR2 MUSK

5.86e-03129533PF07714
DomainEGF_1

STAB2 FBN1 HMCN1 TENM1

5.88e-03255534PS00022
DomainEGF-like_CS

STAB2 FBN1 HMCN1 TENM1

6.38e-03261534IPR013032
DomainEGF_2

STAB2 FBN1 HMCN1 TENM1

6.73e-03265534PS01186
DomainC2

CPNE2 PIK3CA PLCH2

6.92e-03137533SM00239
PathwayREACTOME_CELLULAR_HEXOSE_TRANSPORT

SLC2A14 SLC2A3 SLC5A1 SLC5A2

3.09e-0719444MM14718
PathwayREACTOME_CELLULAR_HEXOSE_TRANSPORT

SLC2A14 SLC2A3 SLC5A1 SLC5A2

4.75e-0721444M27058
PathwayREACTOME_PHYSIOLOGICAL_FACTORS

NPR1 NPR2 GATA4

1.01e-0514443M27459
PathwayWP_NRF2_PATHWAY

SLC2A14 ME1 SLC2A3 SLC5A1 SLC5A2

7.40e-05141445M39454
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLCO1A2 SLC2A14 SLC4A9 SLC2A3 SLC5A1 SLC5A2

8.97e-05238446MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLCO1A2 SLC2A14 SLC4A9 SLC2A3 SLC5A1 SLC5A2

1.15e-04249446M5988
PathwayREACTOME_CA2_ACTIVATED_K_CHANNELS

KCNN1 KCNN3

1.42e-046442MM14543
PathwayREACTOME_PHYSIOLOGICAL_FACTORS

NPR1 NPR2

1.98e-047442MM15201
PathwayKEGG_PYRUVATE_METABOLISM

ME1 ME2 ME3

2.59e-0440443M7934
PathwayREACTOME_CA2_ACTIVATED_K_CHANNELS

KCNN1 KCNN3

3.38e-049442M26932
PathwayREACTOME_VITAMIN_C_ASCORBATE_METABOLISM

SLC2A14 SLC2A3

3.38e-049442MM14769
PathwayREACTOME_PYRUVATE_METABOLISM

ME1 ME2 ME3

3.44e-0444443MM15393
PathwayWP_TCA_CYCLE_IN_SENESCENCE

ME1 ME2

4.22e-0410442M40058
PathwayREACTOME_PYRUVATE_METABOLISM

ME1 ME2 ME3

4.73e-0449443M17157
PathwayBIOCARTA_NFAT_PATHWAY

PIK3CA CAMK4 GATA4

4.73e-0449443MM1442
PathwayBIOCARTA_NFAT_PATHWAY

PIK3CA CAMK4 GATA4

5.32e-0451443M2288
PathwayBIOCARTA_VITCB_PATHWAY

SLC2A14 SLC2A3

6.16e-0412442MM1526
PathwayREACTOME_CARDIAC_CONDUCTION

NPR1 NPR2 GATA4 KCNK7

7.04e-04130444M27454
PathwayBIOCARTA_ACH_PATHWAY

PIK3CA MUSK

8.46e-0414442M16884
PathwayBIOCARTA_PGC1A_PATHWAY

HDAC5 CAMK4

8.46e-0414442MM1473
PathwayBIOCARTA_ACH_PATHWAY

PIK3CA MUSK

8.46e-0414442MM1485
PathwayBIOCARTA_PGC1A_PATHWAY

HDAC5 CAMK4

9.74e-0415442M15181
Pubmed

Oxygen-regulated expression of GLUT-1, GLUT-3, and VEGF in the mouse blastocyst.

SLC2A14 SLC2A3 VEGFA

1.50e-08455315515055
Pubmed

Altered placental function of 11beta-hydroxysteroid dehydrogenase 2 knockout mice.

SLC2A14 SLC2A3 VEGFA

3.12e-07955318845627
Pubmed

GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc.

SLC2A14 SLC2A3 SLC5A1

3.12e-07955336917198
Pubmed

Prolonged endoplasmic reticulum stress alters placental morphology and causes low birth weight.

SLC2A14 SLC2A3 VEGFA

4.46e-071055324370435
Pubmed

Targeted mutation of the murine arylhydrocarbon receptor nuclear translocator 2 (Arnt2) gene reveals partial redundancy with Arnt.

SLC2A14 SLC2A3 VEGFA

6.12e-071155311381139
Pubmed

Placental and fetal characteristics of the Ohia mouse line recapitulate outcomes in human hypoplastic left heart syndrome.

SLC2A14 SLC2A3 VEGFA

2.07e-061655334890862
Pubmed

Reprogramming- and pluripotency-associated membrane proteins in mouse stem cells revealed by label-free quantitative proteomics.

SLC2A14 SLC2A3

2.46e-06255223615220
Pubmed

The pseudokinase domains of guanylyl cyclase-A and -B allosterically increase the affinity of their catalytic domains for substrate.

NPR1 NPR2

2.46e-06255230696704
Pubmed

The DART Study: Results from the Dose-Escalation and Expansion Cohorts Evaluating the Combination of Dalantercept plus Axitinib in Advanced Renal Cell Carcinoma.

SLPI VEGFA

2.46e-06255228031424
Pubmed

Copy-Number Variation of the Glucose Transporter Gene SLC2A3 and Congenital Heart Defects in the 22q11.2 Deletion Syndrome.

SLC2A14 SLC2A3

2.46e-06255225892112
Pubmed

CD205+ polymorphonuclear myeloid-derived suppressor cells suppress antitumor immunity by overexpressing GLUT3.

SLC2A14 SLC2A3

2.46e-06255233368883
Pubmed

Chimeric natriuretic peptide ACNP stimulates both natriuretic peptide receptors, the NPRA and NPRB.

NPR1 NPR2

2.46e-06255223186809
Pubmed

Neuronal functions, feeding behavior, and energy balance in Slc2a3+/- mice.

SLC2A14 SLC2A3

2.46e-06255218780771
Pubmed

Adaptive and Constitutive Activations of Malic Enzymes Confer Liver Cancer Multilayered Protection Against Reactive Oxygen Species.

ME1 ME3

2.46e-06255233619771
Pubmed

Functional roles of the tetramer organization of malic enzyme.

ME1 ME3

2.46e-06255219416979
Pubmed

Molecular determinants of renal glucose reabsorption. Focus on "Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2".

SLC5A1 SLC5A2

2.46e-06255221048164
Pubmed

Expression of mouse-GLUT3 and human-GLUT3 glucose transporter proteins in brain.

SLC2A14 SLC2A3

2.46e-0625521734877
Pubmed

Glypican-1 is a VEGF165 binding proteoglycan that acts as an extracellular chaperone for VEGF165.

GPC1 VEGFA

2.46e-06255210196157
Pubmed

Sevoflurane Induces Learning and Memory Impairment in Young Mice Through a Reduction in Neuronal Glucose Transporter 3.

SLC2A14 SLC2A3

2.46e-06255231884568
Pubmed

ATP potentiates competitive inhibition of guanylyl cyclase A and B by the staurosporine analog, Gö6976: reciprocal regulation of ATP and GTP binding.

NPR1 NPR2

2.46e-06255221828054
Pubmed

Porcine natriuretic peptide type B (pNPPB) maintains mouse oocyte meiotic arrest via natriuretic peptide receptor 2 (NPR2) in cumulus cells.

NPR1 NPR2

2.46e-06255224615855
Pubmed

Temporal and spatial distribution of murine placental and brain GLUT3-luciferase transgene as a readout of in vivo transcription.

SLC2A14 SLC2A3

2.46e-06255223193055
Pubmed

Vasonatrin peptide stimulates both of the natriuretic peptide receptors, NPRA and NPRB.

NPR1 NPR2

2.46e-06255224699414
Pubmed

Guanylyl cyclase (GC)-A and GC-B activities in ventricles and cardiomyocytes from failed and non-failed human hearts: GC-A is inactive in the failed cardiomyocyte.

NPR1 NPR2

2.46e-06255222133375
Pubmed

Gene expression of GLUT3 glucose transporter regulated by glucose in vivo in mouse brain and in vitro in neuronal cell cultures from rat embryos.

SLC2A14 SLC2A3

2.46e-0625528198523
Pubmed

Mitochondrial malic enzyme (E.C.1.1.1.40) in human leukocytes: formal genetics and population genetics.

ME2 ME3

2.46e-062552511162
Pubmed

Guanylyl cyclases A and B are asymmetric dimers that are allosterically activated by ATP binding to the catalytic domain.

NPR1 NPR2

2.46e-06255222949736
Pubmed

Enhanced expression of natriuretic peptide receptor A and B in neutrophils of culprit lesions in patients with acute myocardial infarction.

NPR1 NPR2

2.46e-06255228765884
Pubmed

ATP-independent activation of natriuretic peptide receptors.

NPR1 NPR2

2.46e-06255215911610
Pubmed

Altered lactate metabolism in Huntington's disease is dependent on GLUT3 expression.

SLC2A14 SLC2A3

2.46e-06255229582588
Pubmed

Placental glucose and amino acid transport in calorie-restricted wild-type and Glut3 null heterozygous mice.

SLC2A14 SLC2A3

2.46e-06255222700768
Pubmed

Glucose transporter isoform-3-null heterozygous mutation causes sexually dimorphic adiposity with insulin resistance.

SLC2A14 SLC2A3

2.46e-06255218445753
Pubmed

Sex-Specific Life Course Changes in the Neuro-Metabolic Phenotype of Glut3 Null Heterozygous Mice: Ketogenic Diet Ameliorates Electroencephalographic Seizures and Improves Sociability.

SLC2A14 SLC2A3

2.46e-06255228324109
Pubmed

Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia.

SLC5A1 SLC5A2

2.46e-06255224226519
Pubmed

Expression of the brain-type glucose transporter is restricted to brain and neuronal cells in mice.

SLC2A14 SLC2A3

2.46e-0625521516757
Pubmed

Glucose Transporter 3 Potentiates Degranulation and Is Required for Platelet Activation.

SLC2A14 SLC2A3

2.46e-06255228663252
Pubmed

Cloning and functional characterization of the 5' flanking region of the human mitochondrial malic enzyme gene. Regulatory role of Sp1 and AP-2.

ME1 ME2

2.46e-06255211358520
Pubmed

Thioglycosides as inhibitors of hSGLT1 and hSGLT2: potential therapeutic agents for the control of hyperglycemia in diabetes.

SLC5A1 SLC5A2

2.46e-06255217505558
Pubmed

Neuronal glucose transporter isoform 3 deficient mice demonstrate features of autism spectrum disorders.

SLC2A14 SLC2A3

2.46e-06255219506559
Pubmed

Adenine nucleotides decrease the apparent Km of endogenous natriuretic peptide receptors for GTP.

NPR1 NPR2

2.46e-06255217848634
Pubmed

Canine brain glucose transporter 3: gene sequence, phylogenetic comparisons and analysis of functional sites.

SLC2A14 SLC2A3

2.46e-0625528654954
Pubmed

Renal SGLT mRNA expression in human health and disease: a study in two cohorts.

SLC5A1 SLC5A2

2.46e-06255231545924
Pubmed

State-of-the-art computational methods to predict protein-protein interactions with high accuracy and coverage.

ME2 ME3

2.46e-06255237401192
Pubmed

Mass spectrometric identification of phosphorylation sites in guanylyl cyclase A and B.

NPR1 NPR2

2.46e-06255220977274
Pubmed

Adult glut3 homozygous null mice survive to demonstrate neural excitability and altered neurobehavioral responses reminiscent of neurodevelopmental disorders.

SLC2A14 SLC2A3

2.46e-06255233482226
Pubmed

Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.

SLC5A1 SLC5A2

2.46e-06255220980548
Pubmed

Purification and properties of cytosolic and mitochondrial malic enzyme isolated from human brain.

ME1 ME2

2.46e-0625527757881
Pubmed

Sodium-glucose co-transporter (SGLT)2 and SGLT1 renal expression in patients with type 2 diabetes.

SLC5A1 SLC5A2

2.46e-06255228419670
Pubmed

Molecular mechanism for the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate.

ME1 ME2

2.46e-06255212121650
Pubmed

Expression of Malic Enzymes in Sebaceous Lesions.

ME1 ME2

2.46e-06255226381116
Pubmed

Small-conductance, calcium-activated potassium channels from mammalian brain.

KCNN1 KCNN3

2.46e-0625528781233
Pubmed

Glucose Transporter 3 is Essential for the Survival of Breast Cancer Cells in the Brain.

SLC2A14 SLC2A3

2.46e-06255231817208
Pubmed

Different regulatory properties of the cytosolic and mitochondrial forms of malic enzyme isolated from human brain.

ME1 ME2

2.46e-0625527496989
Pubmed

Brain glucose transporter (Glut3) haploinsufficiency does not impair mouse brain glucose uptake.

SLC2A14 SLC2A3

2.46e-06255221316350
Pubmed

The indolocarbazole, Gö6976, inhibits guanylyl cyclase-A and -B.

NPR1 NPR2

2.46e-06255221366551
Pubmed

NFκB up-regulation of glucose transporter 3 is essential for hyperactive mammalian target of rapamycin-induced aerobic glycolysis and tumor growth.

SLC2A14 SLC2A3

7.36e-06355225578782
Pubmed

Molecular properties of small-conductance Ca2+-activated K+ channels expressed in murine colonic smooth muscle.

KCNN1 KCNN3

7.36e-06355211557517
Pubmed

Quantitative expression analysis of the small conductance calcium-activated potassium channels, SK1, SK2 and SK3, in human brain.

KCNN1 KCNN3

7.36e-06355211146124
Pubmed

Sodium-glucose co-transporter (SGLT) and glucose transporter (GLUT) expression in the kidney of type 2 diabetic subjects.

SLC5A1 SLC5A2

7.36e-06355228477418
Pubmed

Differential expression of small-conductance Ca2+-activated K+ channels SK1, SK2, and SK3 in mouse atrial and ventricular myocytes.

KCNN1 KCNN3

7.36e-06355216055520
Pubmed

Glucose transporter GLUT3: ontogeny, targeting, and role in the mouse blastocyst.

SLC2A14 SLC2A3

7.36e-0635529108057
Pubmed

Improved glycemic control in mice lacking Sglt1 and Sglt2.

SLC5A1 SLC5A2

7.36e-06355223149623
Pubmed

Antibodies to a renal Na+/glucose cotransport system localize to the apical plasma membrane domain of polar mouse embryo blastomeres.

SLC5A1 SLC5A2

7.36e-0635521702069
Pubmed

A sensitive method for determining the phosphorylation status of natriuretic peptide receptors: cGK-Ialpha does not regulate NPR-A.

NPR1 NPR2

7.36e-06355216430226
Pubmed

Skeletal muscle derived Musclin protects the heart during pathological overload.

NPR1 NPR2

7.36e-06355235013221
Pubmed

Significant reduction of the GLUT3 level, but not GLUT1 level, was observed in the brain tissues of several scrapie experimental animals and scrapie-infected cell lines.

SLC2A14 SLC2A3

7.36e-06355224243341
Pubmed

Nerve growth factor regulates the expression of vascular endothelial growth factor in human HaCaT keratinocytes via PI3K/mTOR pathway.

PIK3CA VEGFA

7.36e-06355224615084
Pubmed

Involvement of phosphoinositide 3-kinase class IA (PI3K 110α) and NADPH oxidase 1 (NOX1) in regulation of vascular differentiation induced by vascular endothelial growth factor (VEGF) in mouse embryonic stem cells.

PIK3CA VEGFA

7.36e-06355226553657
Pubmed

Glucose transporter expression in brain. cDNA sequence of mouse GLUT3, the brain facilitative glucose transporter isoform, and identification of sites of expression by in situ hybridization.

SLC2A14 SLC2A3

7.36e-0635521730609
Pubmed

Small conductance Ca2+-activated K+ channel knock-out mice reveal the identity of calcium-dependent afterhyperpolarization currents.

KCNN1 KCNN3

7.36e-06355215190101
Pubmed

Glucose transporter isoform-3 mutations cause early pregnancy loss and fetal growth restriction.

SLC2A14 SLC2A3

7.36e-06355217213475
Pubmed

Characterization and modulation of glucose uptake in a human blood-brain barrier model.

SLC2A3 SLC5A1

7.36e-06355223975336
Pubmed

Gestational changes of glucose transporter gene expression in the mouse placenta and decidua.

SLC2A14 SLC2A3

7.36e-0635528905482
Pubmed

Regular Exercise Enhances Cognitive Function and Intracephalic GLUT Expression in Alzheimer's Disease Model Mice.

SLC2A14 SLC2A3

7.36e-06355231561359
Pubmed

High NOV/CCN3 expression during high-fat diet pregnancy in mice affects GLUT3 expression and the mTOR pathway.

SLC2A14 SLC2A3

7.36e-06355233586490
Pubmed

Hyperglycemia reduces mitochondrial content and glucose transporter expression in mouse embryos developing in vitro.

SLC2A14 SLC2A3

7.36e-06355219550108
Pubmed

Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons.

KCNN1 KCNN3

7.36e-06355224434522
Pubmed

Placental glucose transporter expression is regulated by glucocorticoids.

SLC2A14 SLC2A3

7.36e-06355210199793
Pubmed

Differential regulation of mouse kidney sodium-dependent transporters mRNA by cadmium.

SLC5A1 SLC5A2

7.36e-06355211749115
Pubmed

Glucose transporter proteins in brain.

SLC2A14 SLC2A3

7.36e-0635527926364
Pubmed

Molecular cloning of murine homologue dentatorubral-pallidoluysian atrophy (DRPLA) cDNA: strong conservation of a polymorphic CAG repeat in the murine gene.

SLC2A14 SLC2A3

7.36e-0635529070948
Pubmed

Glucose Metabolism Is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes.

SLC2A14 SLC2A3

7.36e-06355230765335
Pubmed

Evidence for a family of human glucose transporter-like proteins. Sequence and gene localization of a protein expressed in fetal skeletal muscle and other tissues.

SLC2A14 SLC2A3

7.36e-0635523170580
Pubmed

Comparative immunohistochemical distribution of three small-conductance Ca2+-activated potassium channel subunits, SK1, SK2, and SK3 in mouse brain.

KCNN1 KCNN3

7.36e-06355215234350
Pubmed

Calpain I Activation Causes GLUT3 Proteolysis and Downregulation of O-GlcNAcylation in Alzheimer's Disease Brain.

SLC2A14 SLC2A3

7.36e-06355229614685
Pubmed

Small-conductance calcium-activated K(+) channels 3 (SK3) regulate blastocyst hatching by control of intracellular calcium concentration.

KCNN1 KCNN3

7.36e-06355222416006
Pubmed

Peritoneal Expression of SGLT-2, GLUT1, and GLUT3 in Peritoneal Dialysis Patients.

SLC2A3 SLC5A2

7.36e-06355234781282
Pubmed

Partial apamin sensitivity of human small conductance Ca2+-activated K+ channels stably expressed in Chinese hamster ovary cells.

KCNN1 KCNN3

7.36e-06355212382077
Pubmed

Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence.

ME1 ME2

7.36e-06355223334421
Pubmed

Regulation of natriuretic peptides postprandially in vivo and of their receptors in adipocytes by fatty acids in vitro.

NPR1 NPR2

7.36e-06355229409758
Pubmed

Knockdown of malic enzyme 2 suppresses lung tumor growth, induces differentiation and impacts PI3K/AKT signaling.

PIK3CA ME2

7.36e-06355224957098
Pubmed

Cardiac small conductance Ca2+-activated K+ channel subunits form heteromultimers via the coiled-coil domains in the C termini of the channels.

KCNN1 KCNN3

7.36e-06355220689065
Pubmed

LPCAT1 Facilitates Keratinocyte Hyperproliferation and Skin Inflammation in Psoriasis by Regulating GLUT3.

SLC2A14 SLC2A3

7.36e-06355238246582
Pubmed

Chromosomal distribution of three members of the human natriuretic peptide receptor/guanylyl cyclase gene family.

NPR1 NPR2

7.36e-0635521979052
Pubmed

Recurrent moderate hypoglycemia accelerates the progression of Alzheimer's disease through impairment of the TRPC6/GLUT3 pathway.

SLC2A14 SLC2A3

7.36e-06355235077394
Pubmed

Cardiac fibrosis in end-stage human heart failure and the cardiac natriuretic peptide guanylyl cyclase system: regulation and therapeutic implications.

NPR1 NPR2

7.36e-06355225117468
Pubmed

Retinal degeneration protein 3 controls membrane guanylate cyclase activities in brain tissue.

NPR1 NPR2

7.36e-06355236618828
Pubmed

Vitamin C enters mouse T cells as dehydroascorbic acid in vitro and does not recapitulate in vivo vitamin C effects.

SLC2A14 SLC2A3

7.36e-06355219327547
Pubmed

Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2.

SLC5A1 SLC5A2

7.36e-06355230132032
Pubmed

Down-regulation does not mediate natriuretic peptide-dependent desensitization of natriuretic peptide receptor (NPR)-A or NPR-B: guanylyl cyclase-linked natriuretic peptide receptors do not internalize.

NPR1 NPR2

7.36e-06355215459247
GeneFamilyPotassium calcium-activated channels

KCNN1 KCNN3

6.76e-056392255
GeneFamilyGuanylate cyclase receptors

NPR1 NPR2

9.46e-057392343
GeneFamilySolute carriers

SLCO1A2 SLC2A14 SLC4A9 SLC2A3 SLC5A1 SLC5A2

1.86e-04395396752
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

KIRREL3 HMCN1 MUSK

5.01e-03161393593
CoexpressionMOOTHA_GLUCONEOGENESIS

ME1 ME2 ME3

3.77e-0531553M13448
CoexpressionGSE29949_CD8_POS_DC_SPLEEN_VS_DC_BRAIN_DN

NPR2 SLCO1A2 KCNN3 UNC93A ME1

5.43e-05194555M8408
CoexpressionSHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4

NPR1 PPP2R3A HDAC5 DLEC1 ME3

5.84e-05197555M12824
CoexpressionGSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_DN

PLCH2 DLEC1 SLC2A3 VEGFA ZNF44

6.13e-05199555M5264
CoexpressionGSE22935_UNSTIM_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP

TSPAN12 NPR2 STAB2 CSNK1G3 YIPF7

6.28e-05200555M7765
CoexpressionGSE27786_NKCELL_VS_ERYTHROBLAST_DN

NPR1 NPR2 PLCH2 SLCO1A2 IPP

6.28e-05200555M4854
CoexpressionGSE360_DC_VS_MAC_M_TUBERCULOSIS_DN

PLCH2 RECQL5 DLEC1 ME1 VEGFA

6.28e-05200555M5191
CoexpressionLOCKWOOD_AMPLIFIED_IN_LUNG_CANCER

SETDB1 NPR1 PIK3CA SEC23A VEGFA

9.03e-05216555M4572
CoexpressionAtlasStromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4

TSPAN12 CPNE2 NPR1 NPR2 STAB2 FBN1 HMCN1 ME1

1.23e-05439538GSM777059_500
CoexpressionAtlasStromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4

TSPAN12 CPNE2 NPR1 NPR2 STAB2 FBN1 HMCN1 ME1

1.47e-05450538GSM777063_500
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 NPR1 STAB2 HMCN1 GATA4

4.24e-0619555512ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TSPAN12 KIRREL3 NPR1 SLCO1A2 SLPI

4.35e-0619655534e79918a448f6c19b87e1b1ce13c012b24be1f8
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TSPAN12 KIRREL3 NPR1 SLCO1A2 SLPI

4.35e-061965558f82e01ca50aa4cd6149547505b4474a02fad618
ToppCellSerous|World / shred by cell class for turbinate

KIRREL3 SLCO1A2 SLPI SLC5A1

3.55e-051505546a326662d58b0f17d6efa8cc28571f4cbbf57c2d
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Fos_(Deep_layer_pyramidal_cells_(IEG))-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

UNC93A KCNK7 SLC5A1

3.88e-05535531593743b4ab678670e569c3e68174f508ad8e843
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Fos_(Deep_layer_pyramidal_cells_(IEG))|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

UNC93A KCNK7 SLC5A1

3.88e-05535533f206f9c095676e0abb889306a36608b08b0fce3
ToppCellfacs-Lung-EPCAM-24m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR158 SLPI SLC4A9 SLC2A3

4.24e-05157554d2cb261a9ee2c90e2e0fc656bd6413fbccb465fc
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR158 SLPI SLC4A9 SLC2A3

4.24e-05157554350069e4d2dbddc82e813e2a2cc43032daa23605
ToppCell18-Distal-Epithelial-Basal_cell|Distal / Age, Tissue, Lineage and Cell class

PLCH2 UGGT1 SLPI SLC2A14

4.34e-05158554183f445967e09e871c93d8e94781ed9fec894169
ToppCelldroplet-Spleen-nan-18m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 SLPI SLC2A3 VEGFA

4.90e-05163554bc37c5d9f48b16096d5313657563f3ec84028c8c
ToppCelldroplet-Heart-nan-24m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 CAMK4 ARHGAP25 SLC2A3

5.39e-05167554a35ace2c722936d2a3e1f0826e5b6ec6b1340d2b
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3|TCGA-Stomach / Sample_Type by Project: Shred V9

HMCN1 CAMK4 ARHGAP25 MUSK

5.39e-05167554d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCell(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts|(0)_Normal/No_Treatment / Stress and Cell class

GPC1 ME1 ME2 SEC23A

6.18e-05173554c2a0f674681836b5a868c13f67caa7d555ef6519
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NPR1 FBN1 HMCN1 MUSK

6.32e-051745541d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMK4 PLCH2 SLPI TENM1

6.46e-0517555465571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCelldroplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 STAB2 SLPI GATA4

6.60e-051765543494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCelldroplet-Liver-Npc-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 STAB2 SLPI GATA4

6.60e-05176554d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TSPAN12 KIRREL3 NPR1 SLCO1A2

7.36e-051815545f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TSPAN12 KIRREL3 NPR1 SLCO1A2

7.36e-05181554c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 KCNN1 ME3 SLC5A1

7.68e-051835546b5fa169477821355d1ab7aa11935cdfde1c339c
ToppCell10x5'v1-week_12-13-Endothelial-stroma-sinusoidal_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TSPAN12 NPR1 STAB2 HMCN1

8.18e-05186554e8ead5634686ebaa6a230eea69795d923ce9939d
ToppCelldroplet-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 KIRREL3 NPR1 HMCN1

8.35e-0518755464dd28b23eda7dfb7fd069be2742de7bad0fd87a
ToppCelldroplet-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 KIRREL3 NPR1 HMCN1

8.35e-05187554b535d5447bf15e95dcf025a0a455628b956fc857
ToppCell18-Airway-Epithelial-Submucosal_gland|Airway / Age, Tissue, Lineage and Cell class

TSPAN12 SLCO1A2 SLPI SLC5A1

8.70e-05189554c1ea2dc44cf5340378e56e0ffc2e6f64e6c95a58
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 PPP2R3A ME3 SLC5A1

9.06e-051915545a5b5402a077b3189ca156f2bac5f47ad780aebf
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 PPP2R3A ME3 SLC5A1

9.06e-0519155478bcce497920cc5b3bef083eab50deb1cc82cd2e
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 NPR1 STAB2 GATA4

9.06e-051915541924af7d8b0a0b892e480a9fd6d874941b0c0b5d
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 NPR1 STAB2 GATA4

9.06e-0519155488f91e57a1409bdeb91e9bf47510a6fb998a1bf5
ToppCell10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TSPAN12 NPR1 STAB2 HMCN1

9.06e-05191554dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCellLPS-antiTNF-Endothelial-Endothelial-Artery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBN1 HMCN1 KCNN3 GRM8

9.06e-051915544b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCellLPS_only-Endothelial-Endothelial-Vein|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NPR1 HMCN1 SLPI ME3

9.25e-0519255452acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 NPR1 STAB2 GATA4

9.25e-051925542bfac6b3956265205ca47d06888851ed68b65999
ToppCellLPS-IL1RA-Endothelial-Endothelial-Vein|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NPR1 HMCN1 SLPI ME3

9.25e-05192554717f3d3bbee4d0f64ba1341ee2b00a407ba1e0f3
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 NPR1 STAB2 GATA4

9.25e-05192554d525f7f088a53110912600a7c9f6d33b9270d534
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 NPR1 STAB2 GATA4

9.62e-05194554c8b9551b93a5aed62154b487db90130604a6125c
ToppCellIPF-Stromal-Fibroblast|Stromal / Disease state, Lineage and Cell class

NPR1 FBN1 SLPI VEGFA

9.62e-05194554da3e1d39575969a069ef43e552afe94b2f441d0b
ToppCell10x5'v1-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TSPAN12 NPR1 STAB2 HMCN1

9.62e-05194554e141beafc9252e5d8c949252bfab53e127c881dc
ToppCell10x5'v1-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TSPAN12 NPR1 STAB2 HMCN1

9.62e-05194554953578102ffc7b612ee8fce45e414750800fef5d
ToppCelldroplet-Lung-30m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TSPAN12 NPR1 HMCN1 VEGFA

9.62e-05194554fc3f81b5bdc544a69c355e482f002643e029a7b0
ToppCell10x5'v1-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TSPAN12 NPR1 STAB2 HMCN1

9.82e-0519555422a481927147ec4ae9d59e6af7c87df0e9cb51e4
ToppCelldroplet-Lung-30m-Endothelial-capillary_endothelial-capillary_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TSPAN12 NPR1 HMCN1 VEGFA

1.00e-041965549e737eaa98fd49972fce64d1d4a4d1f34b9bcb96
ToppCelldroplet-Lung-30m-Endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TSPAN12 NPR1 HMCN1 VEGFA

1.00e-0419655458871891185aa7e1e4ab9b99cd25c1ca3c932cc8
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 NPR1 STAB2 GATA4

1.00e-0419655481900dcc9451ff6606ec940c16b559d73247590e
ToppCelldroplet-Lung-30m-Endothelial-capillary_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TSPAN12 NPR1 HMCN1 VEGFA

1.00e-0419655499a7f2e57774884216525897dcd32a289107548b
ToppCellCOPD-Stromal-Fibroblast|Stromal / Disease state, Lineage and Cell class

NPR1 FBN1 SLPI SLC2A3

1.00e-041965544930eeb303d174c28fd91021723e26fdf1af9170
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 NPR1 STAB2 GATA4

1.02e-04197554d584d0334ea97e3fa8c4cd869f5eeea2c7a1ed04
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 NPR1 STAB2 GATA4

1.02e-04197554412091994196a06c2779b4c2cfed84be889a5f8d
ToppCellTCGA-Skin-Metastatic-Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

MSH6 PIK3CA ARHGAP25 SEC23A

1.04e-04198554af4fb9eb2295c7b90624b38ba25619aa15254efa
ToppCellTCGA-Skin-Metastatic|TCGA-Skin / Sample_Type by Project: Shred V9

MSH6 PIK3CA ARHGAP25 SEC23A

1.04e-04198554ad39cce004867f083f8da1954e0cf5a263815184
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

MSH6 PIK3CA ARHGAP25 SEC23A

1.04e-0419855462cbf4b29e8af4983fb47a17f96da62682a5137e
ToppCell10x3'2.3-week_14-16-Endothelial|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TSPAN12 NPR1 STAB2 KCNN3

1.06e-0419955441f046646fff65b7e51b63d3204f76ef32054781
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FBN1 HMCN1 TENM1 MUSK

1.06e-04199554e1f1950d6f840485e263b83dc81b98910be3ae7a
ToppCell10x3'2.3-week_14-16-Endothelial-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TSPAN12 NPR1 STAB2 KCNN3

1.06e-04199554ef7f7f7c861827574b120f48cf4052c563929081
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PPP2R3A SLCO1A2 SLPI SLC5A1

1.08e-042005547c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FBN1 HMCN1 TENM1 KCNN3

1.08e-0420055458b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Stem_cells-neuroepithelial-like_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

NPR2 SLCO1A2 TENM1

5.18e-041275539071cd0953c8bb6746dc9cd13d153e3d6ef40b08
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3|Hippocampus / BrainAtlas - Mouse McCarroll V32

ARHGAP25 RWDD2A GRM8

6.59e-04138553b63e26afafbd2cdeed9c9451e6f530ab6295504c
ToppCellCOVID-19-Fibroblasts-Mesothelial_FB|COVID-19 / group, cell type (main and fine annotations)

OR2C1 KIRREL3 GRM8

7.02e-041415537e6dcccb74e7ee90b69dc91b59491b84f3a713c9
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLPI ARHGAP25 SLC2A3

7.46e-041445531efa434e577d1f87e02df01667782f414d63bd60
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLPI ARHGAP25 SLC2A3

7.46e-04144553c0c5f254a960ba5e5f1354599d54e77360e6c2ac
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GPC1 SLCO1A2 SLPI

7.61e-041455538da10bc6611976e1ec85e09f04a2dc5bf6555c9e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC2A14 TENM1 KCNK7

7.76e-04146553deeb2c90a478deac7805e1f0d1466bf5bc42f746
ToppCell(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

GPC1 ME2 SEC23A

7.92e-0414755387c24843cb0e87ad42e725d08423131a5d2d25a3
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIRREL3 HMCN1 SLPI

8.07e-04148553b4632029ebd14969bda59a1bd1454eadb8efe563
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIRREL3 HMCN1 SLPI

8.07e-04148553ba277c898678dd36f8dc1d681301c71901b89055
ToppCell-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

CAMK4 YIPF7 SLC2A3

8.07e-041485539952747a42e7875db92325f8edfab324951b29cc
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIRREL3 NPR1 STAB2

8.23e-04149553cc6224c6b79f43b97adc1ce48ca4906bff2ad318
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIRREL3 NPR1 STAB2

8.23e-0414955324a7538b54b2a5291503c7493fefed4e45e8d710
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CPNE2 KIRREL3 GRM8

8.23e-0414955310ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CPNE2 SLPI SLC2A3

8.23e-041495534de52569611e63a780cde9bd111d6d9c11a05a11
ToppCellfacs-Trachea-nan-3m-Myeloid-granulocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLPI ARHGAP25 SLC2A3

8.23e-041495539c4837aa63e46382ff45a41c72beb5722b3ada19
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CPNE2 SLPI SLC2A3

8.23e-04149553c957ac23ad6343eacce7e6be4a6d3ac043af4f86
ToppCellLPS-antiTNF-Stromal_mesenchymal-Fibroblasts-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLPI ME1 ZNF124

8.55e-04151553f13a117ae26ae525da4f3e837d8f204d00dc6ee3
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CPNE2 NPR2 PPP2R3A

9.06e-041545538dc8f02534c3ebda30bf9e702e36d0c53d89e5a5
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIRREL3 GPR158 ME1

9.06e-04154553e94cd11488003347120eacd3ced0a8923ed09ccc
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CPNE2 KIRREL3 GRM8

9.23e-04155553cba6f3f7742b4d5d54ad0a0ac0dd4016e73fe658
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNN3 ARHGAP25 SLC2A3

9.23e-041555530e24e767a3895d31d34cabeaca0354aadae34e44
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CPNE2 KIRREL3 GRM8

9.23e-0415555399e749f7075e2c64e9a0bf91009f95b6969197c8
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNN3 ARHGAP25 SLC2A3

9.23e-04155553f3489a548a2c0cc2d9117ff85865c6089ea0835d
ToppCellVE-Treg-naive_CD4|VE / Condition, Cell_class and T cell subcluster

HMCN1 PIK3CA UGGT1

9.40e-041565536501baf73616e702946de9fb13d267e30a68888b
ToppCellfacs-Spleen-nan-24m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 SLPI SLC2A3

9.40e-04156553034d4359359a44c205c6931f38a375271ac2752b
ToppCellfacs-Spleen-nan-24m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 SLPI SLC2A3

9.40e-041565532a4dac4100c0339aad4905b8eaca6e8fe806718b
ToppCellfacs-Spleen-nan-24m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 SLPI SLC2A3

9.40e-0415655321267718d3a3dc19988663b6846aed8bb3eae836
ToppCellfacs-Lung-24m-Hematologic-myeloid-neutrophil|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR158 SLPI SLC2A3

9.57e-04157553e96241db2b5ff52b230e3e33207e7bb968900cab
ToppCellfacs-Lung-24m-Hematologic-myeloid-neutrophil-neutrophil|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR158 SLPI SLC2A3

9.57e-0415755307a0f8d29a3111be670eae030a91474465eba734
ToppCelldroplet-Lung-LUNG-1m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 SLPI SLC2A3

9.75e-0415855330cceb73cf5e24b692da84d33342fd3b1ad5efe5
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NPR1 ARHGAP25 GRM8

9.75e-041585539e0589f770920f8ac41cfe5cd0a29e9e7a04a308
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 SLPI SLC2A3

9.75e-0415855347793463640f98ee5f680a1ee5786b453355fd57
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPC1 CAMK4 GRM8

9.93e-041595534750ba9ca06ed97b18df3c74eeb51d3ac8763f63
ToppCellIIF-Lymphocyte-T_NK-ILC|IIF / Disease, Lineage and Cell Type

FBN1 IPP SLC5A2

9.93e-0415955355e4f21548f480ca414c00cbff5ec3b13bafd271
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

FBN1 HMCN1 SLC4A9

9.93e-041595533f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCelldroplet-Lung-nan-21m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 SLPI SLC2A3

9.93e-04159553555ebf719504980c7584203a3ee1ba5779ab76d8
ToppCelldroplet-Lung-1m-Hematologic-myeloid-neutrophil-neutrophil|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPNE2 SLPI SLC2A3

9.93e-04159553be54b910ccb73e37eb81945bbad9a89d2bcec34b
ToppCelldroplet-Lung-1m-Hematologic-myeloid-neutrophil|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPNE2 SLPI SLC2A3

9.93e-04159553178678173b005cb8225472306657f0d8289b133b
ToppCelldroplet-Lung-nan-21m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 SLPI SLC2A3

9.93e-04159553a6a5cded6da02a112e04c2c71ce08cc27c1c5002
ToppCell(1)_Control_(PBS)-(4)_COL2.3+_osteoblasts|(1)_Control_(PBS) / Stress and Cell class

GPC1 SLPI ME2

1.01e-031605538450466fc2465c56798df2b520edd23c2c2e941c
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HMCN1 PLCH2 KCNK7

1.03e-03161553da9eecf919866a9c579d7a707a996cf335213134
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HMCN1 PLCH2 KCNK7

1.03e-03161553d431625c32f59a6b552191f3adc5198bd16ad5cf
ToppCellBAL-Mild-cDC_5|Mild / Compartment, Disease Groups and Clusters

NPR2 FBN1 SLC2A3

1.03e-031615537a6e8ed0b5d999efce8945d8083ab01d71be9a92
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-1|TCGA-Kidney / Sample_Type by Project: Shred V9

KCNN3 SLC5A1 VEGFA

1.03e-031615536cacae4a759ace763597ee394cff498dc5d96f74
Drug3-O-methyl-alpha-D-glucopyranose

PIK3CA SLC2A14 SLC2A3 SLC5A1 SLC5A2

2.60e-0757555CID000083246
DrugPiperine [94-62-2]; Down 200; 14uM; MCF7; HT_HG-U133A

MSH6 SETDB1 NPR2 PPP2R3A PIK3CA PTDSS2 SEC23A

3.92e-071925574830_DN
Drug3-O-methyl-D-glucose

PIK3CA SLC2A14 SLC2A3 SLC5A1 SLC5A2

8.45e-0772555CID000008973
DrugMeta Vanadate

ME1 ME2 ME3

1.11e-069553CID000445092
Drugbeta-sulfinylpyruvate

ME1 ME2 ME3

2.17e-0611553CID000000110
DrugD-402

ME1 ME2 ME3

2.17e-0611553CID005744486
DrugErythrityl Tetranitrate

NPR1 NPR2

5.73e-062552DB01613
Drugbenzylphenol

SLC5A1 SLC5A2

5.73e-062552CID000024216
DrugTartronate

ME2 ME3

5.73e-062552DB03680
Drugbeta-D-glucopyranosylphenyl isothiocyanate

SLC5A1 SLC5A2

5.73e-062552CID004182945
Drugsergliflozin

SLC5A1 SLC5A2

5.73e-062552CID009824918
DrugAcebutolol hydrochloride [34381-68-5]; Up 200; 10.8uM; PC3; HG-U133A

SETDB1 RECQL5 PTDSS2 SEC23A SLC5A1 ZNF124

7.47e-061955561911_UP
DrugQuinic acid [86-68-0]; Down 200; 19.6uM; PC3; HT_HG-U133A

SETDB1 RECQL5 TENM1 RWDD2A ME3 VEGFA

7.69e-061965567317_DN
Drugbumetanide

NPR1 FBN1 SLCO1A2 SLC4A9 SLC5A1 SLC5A2

1.11e-05209556CID000002471
DrugT 1095

SLC2A14 SLC2A3 SLC5A2

1.48e-0520553CID006918410
DrugNesiritide

NPR1 NPR2

1.72e-053552DB04899
DrugThallium

KCNN1 KCNN3 GRM8

1.99e-0522553ctd:D013793
Drugnitrofen

NPR1 NPR2 FBN1 PIK3CA GATA4 VEGFA

2.26e-05237556ctd:C007350
Drughydroxymalonate

ME1 ME2 ME3

2.28e-0523553CID000000044
DrugSKA-31

KCNN1 KCNN3

3.43e-054552CID000094880
DrugApamin

KCNN1 KCNN3

3.43e-054552ctd:D001030
DrugD-K-I

CAMK4 CSNK1G3

3.43e-054552CID005330812
DrugAC1MBZ1C

NPR1 NPR2 PIK3CA CAMK4 GRM8 SLC5A1 VEGFA

3.90e-05387557CID000003541
Drugphlorizine

SLC2A14 SLC2A3 SLC5A1 SLC5A2

4.00e-0579554CID000004789
Drugdiethylenetriamine

NPR1 NPR2 SLC2A14 SLC2A3

4.00e-0579554CID000008111
Drughyaluronan

GPC1 MSH6 FBN1 PIK3CA GRM8 VEGFA

4.05e-05263556CID000024759
Drugcalmidazolium chloride

NPR1 CAMK4 SLCO1A2 KCNN1 KCNN3

4.22e-05160555CID000002531
DrugLaevuflex

SLC2A14 ME1 ME2 SLC2A3 ME3 SLC5A1

4.88e-05272556CID000003426
DrugAC1L1CV3

PIK3CA CSNK1G3 GATA4 SLC5A1 SLC5A2

5.47e-05169555CID000002076
Drugsenicapoc

KCNN1 KCNN3

5.70e-055552CID000216327
Drug5-methylisatin

NPR1 NPR2

5.70e-055552CID000011840
Drug3-OMG

SLC2A14 SLC2A3 SLC5A1

6.91e-0533553CID000097217
DrugOD-q

NPR1 NPR2 KCNN1 KCNN3 VEGFA

7.19e-05179555CID000001456
DrugBAPTA-AM

PIK3CA CAMK4 KCNN1 KCNN3 GRM8 SLC5A2

7.37e-05293556CID000002293
Drugglycylsarcosine

SLCO1A2 SLC5A1 SLC5A2

8.26e-0535553CID000093131
Drug6-o-phosphonohexose

SLC2A14 ME1 ME2 SLC2A3 ME3

8.40e-05185555CID000099058
Drugresveratrol; Up 200; 10uM; MCF7; HT_HG-U133A_EA

PPP2R3A HDAC5 RWDD2A GRM8 VEGFA

8.40e-05185555841_UP
Drugtetramisole

ME1 ME2 MUSK ME3

8.94e-0597554CID000003913
Drug0175029-0000 [211245-78-2]; Up 200; 10uM; PC3; HT_HG-U133A

FBN1 GRM8 MUSK SEC23A VEGFA

1.00e-041925556875_UP
DrugMethotrimeprazine maleat salt [7104-38-3]; Up 200; 9uM; PC3; HT_HG-U133A

HDAC5 TENM1 RWDD2A ME3 SLC5A2

1.05e-041945557399_UP
DrugAntazoline hydrochloride [2508-72-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A

GPC1 NPR1 CAMK4 KCNN1 GRM8

1.05e-041945553173_UP
DrugFlucloxacillin sodium [1847-24-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A

HDAC5 CAMK4 TENM1 ARHGAP25 GRM8

1.05e-041945556507_UP
DrugGuanfacine hydrochloride [29110-48-3]; Down 200; 14.2uM; PC3; HT_HG-U133A

PPP2R3A ME3 SLC5A2 ZNF124 ZNF44

1.08e-041955554660_DN
DrugMiconazole [22916-47-8]; Up 200; 9.6uM; MCF7; HT_HG-U133A

SLCO1A2 KCNN1 GRM8 MUSK SLC2A3

1.08e-041955554960_UP
DrugPhenethicillin potassium salt [132-93-4]; Down 200; 10uM; PC3; HT_HG-U133A

NPR2 HDAC5 SLCO1A2 TENM1 SLC5A2

1.08e-041955555763_DN
DrugGlycocholic acid [475-31-0]; Down 200; 8.6uM; MCF7; HT_HG-U133A

NPR2 PPP2R3A CAMK4 RECQL5 SLPI

1.08e-041955553315_DN
Drugtrichostatin A; Up 200; 0.1uM; HL60; HG-U133A

HDAC5 ARHGAP25 DLEC1 SLC2A3 SEC23A

1.08e-04195555364_UP
DrugSulfathiazole [72-14-0]; Up 200; 15.6uM; PC3; HG-U133A

PPP2R3A UGGT1 RECQL5 ZNF124 VEGFA

1.08e-041955551883_UP
DrugErgocryptine-alpha [511-09-1]; Up 200; 7uM; PC3; HT_HG-U133A

NPR1 KCNN1 ARHGAP25 GRM8 SLC5A1

1.10e-041965553817_UP
DrugY-27632; Up 200; 3uM; MCF7; HT_HG-U133A_EA

PPP2R3A RECQL5 GRM8 ME3 ZNF44

1.10e-04196555832_UP
DrugPempidine tartrate [546-48-5]; Up 200; 13uM; MCF7; HT_HG-U133A

FBN1 CAMK4 RECQL5 KCNN1 GRM8

1.10e-041965556027_UP
Drugestradiol, USP; Down 200; 0.01uM; ssMCF7; HG-U133A

NPR2 STAB2 CAMK4 DLEC1 SLC5A2

1.10e-04196555373_DN
Drug(+/-)-blebbistatin; Up 200; 17uM; MCF7; HT_HG-U133A_EA

PPP2R3A RECQL5 SLPI GRM8 VEGFA

1.10e-04196555837_UP
DrugFluoxetine hydrochloride [59333-67-4]; Down 200; 11.6uM; MCF7; HT_HG-U133A

STAB2 CAMK4 RECQL5 SLPI PTDSS2

1.13e-041975553314_DN
DrugMinoxidil [38304-91-5]; Up 200; 19.2uM; PC3; HT_HG-U133A

NPR1 SLCO1A2 GRM8 SLC5A2 ZNF44

1.16e-041985554216_UP
DrugBromperidol [10457-90-6]; Up 200; 9.6uM; HL60; HG-U133A

STAB2 HDAC5 RECQL5 KCNN1 RWDD2A

1.16e-041985551723_UP
DrugClonidine hydrochloride [4205-91-8]; Up 200; 15uM; MCF7; HT_HG-U133A

NPR1 PPP2R3A CAMK4 SLPI GRM8

1.16e-041985553172_UP
Drugl 1400

KCNN1 KCNN3

1.19e-047552CID000015548
DrugBisoprolol fumarate; Up 200; 9uM; MCF7; HT_HG-U133A

STAB2 SLPI GRM8 SLC5A2 VEGFA

1.21e-042005552642_UP
DrugSertaconazole nitrate [99592-39-9]; Up 200; 8uM; HL60; HT_HG-U133A

GPC1 NPR1 FBN1 RECQL5 SLC5A2

1.21e-042005556128_UP
DrugKhellin [82-02-0]; Up 200; 15.4uM; MCF7; HT_HG-U133A

STAB2 HDAC5 PTDSS2 SLC5A2 VEGFA

1.21e-042005551504_UP
DrugMeprylcaine hydrochloride [956-03-6]; Up 200; 14.8uM; HL60; HT_HG-U133A

GPC1 NPR1 PLCH2 KCNN1 VEGFA

1.21e-042005556123_UP
DrugYC-1 compound

NPR1 NPR2 VEGFA

1.33e-0441553CID000005712
DrugSkl tripeptide

ME1 ME2 ME3

1.43e-0442553CID000131223
Drug7-OMEN

NPR1 RECQL5

1.59e-048552CID000051370
Drug2-bromoethylamine

NPR1 NPR2

1.59e-048552ctd:C004504
DrugNSC-327434

SLC2A14 SLC2A3

1.59e-048552CID000332025
DrugL-I TC

SLC2A14 SLC2A3

1.59e-048552CID000129434
DrugThioredoxin Sulfide

ME1 ME2 ME3

1.76e-0445553CID006857408
Drugalpha-methyl-D-mannoside

SLC2A14 SLC2A3 SLC5A1 SLC5A2

1.79e-04116554CID000002108
DrugAp 811

NPR1 NPR2

2.04e-049552CID000130279
Drugphosphocreatine disodium

CAMK4 ME1 ME2 ME3

2.45e-04126554CID000000587
Drugguanidine hydrochloride

GPC1 ME1 ME2 ME3

2.68e-04129554CID000005742
Drugphloretin

SLC2A14 SLC2A3 SLC5A1 SLC5A2

2.84e-04131554CID000004788
DrugAC1L1IR1

CAMK4 KCNN1 KCNN3

3.03e-0454553CID000004697
DrugL-NNA

NPR1 NPR2 KCNN1 KCNN3 VEGFA

3.05e-04244555CID000004367
DrugBiggam

ME1 ME3

3.11e-0411552CID000196426
Drugethylidene glucose

SLC2A14 SLC2A3

3.11e-0411552CID000093075
DrugDequalinium

KCNN1 VEGFA

3.11e-0411552ctd:D003868
DrugAC1L1KC5

NPR1 PIK3CA CAMK4 KCNN1 PTDSS2 GRM8 VEGFA

3.11e-04541557CID000005428
DrugSQ22536

NPR1 NPR2 KCNN1 KCNN3

3.19e-04135554CID000005270
Diseaselysophosphatidylethanolamine 20:4 measurement

SLCO1A2 MUSK SEC23A

2.16e-0529553EFO_0010370
DiseasePortal Hypertension

KCNN3 VEGFA

3.40e-055552C0020541
Disease1-eicosatrienoylglycerophosphocholine measurement

SLCO1A2 MUSK

7.12e-057552EFO_0021081
Disease2-arachidonoyl-GPE (20:4) measurement

SLCO1A2 MUSK

9.48e-058552EFO_0800260
Disease1-linoleoyl-GPE (18:2) measurement

SLCO1A2 MUSK

9.48e-058552EFO_0800247
Diseaseresponse to selective serotonin reuptake inhibitor, body mass index

GPC1 PLCH2

9.48e-058552EFO_0004340, EFO_0005658
Diseasecataract (biomarker_via_orthology)

SLC2A14 SLC2A3

2.63e-0413552DOID:83 (biomarker_via_orthology)
Diseaseomega-3 polyunsaturated fatty acid measurement, diet measurement

RWDD2A ME1

4.03e-0416552EFO_0008111, EFO_0010119
DiseaseKeloid

GPC1 FOXL2NB

4.56e-0417552EFO_0004212
Diseasecholelithiasis

GATA4 KCNN3 MUSK

6.01e-0488553EFO_0004799
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

PPP2R3A CSNK1G3 MUSK VEGFA

6.99e-04215554EFO_0008317, EFO_0008591
Diseasemiddle cerebral artery infarction (biomarker_via_orthology)

HDAC5 SLPI VEGFA

7.06e-0493553DOID:3525 (biomarker_via_orthology)
Diseasecolorectal carcinoma (is_implicated_in)

MSH6 PIK3CA

7.69e-0422552DOID:0080199 (is_implicated_in)
Diseasebone density

TSPAN12 HDAC5 CSNK1G3 ARHGAP25 ESPL1

7.77e-04388555EFO_0003923
Diseasetotal cholesterol measurement, very low density lipoprotein cholesterol measurement

PPP2R3A CSNK1G3 MUSK VEGFA

8.14e-04224554EFO_0004574, EFO_0008317
Diseasecholesteryl ester measurement, very low density lipoprotein cholesterol measurement

PPP2R3A CSNK1G3 MUSK VEGFA

8.28e-04225554EFO_0008317, EFO_0010351
Diseasevery low density lipoprotein cholesterol measurement, phospholipid measurement

PPP2R3A CSNK1G3 MUSK VEGFA

8.84e-04229554EFO_0004639, EFO_0008317
Diseasecongenital heart disease (is_implicated_in)

GATA4 VEGFA

9.17e-0424552DOID:1682 (is_implicated_in)
Diseasebreast cancer (implicated_via_orthology)

MSH6 PIK3CA

9.96e-0425552DOID:1612 (implicated_via_orthology)
Diseasecortical thickness

NPR2 FBN1 SLCO1A2 FOXL2NB DLEC1 ME1 ME2 MUSK

1.01e-031113558EFO_0004840
Diseasegallstones

GATA4 MUSK VEGFA

1.09e-03108553EFO_0004210
DiseaseHereditary non-polyposis colorectal cancer syndrome

MSH6 PIK3CA

1.16e-0327552C1112155
Diseasefactor VIII measurement, von Willebrand factor measurement

KIRREL3 STAB2

1.16e-0327552EFO_0004629, EFO_0004630
Diseaseprimary biliary cholangitis (biomarker_via_orthology)

SLCO1A2 VEGFA

1.25e-0328552DOID:12236 (biomarker_via_orthology)
Diseasechronic obstructive pulmonary disease (biomarker_via_orthology)

SLPI VEGFA

1.25e-0328552DOID:3083 (biomarker_via_orthology)
DiseaseNeoplasm of uncertain or unknown behavior of ovary

MSH6 PIK3CA

1.34e-0329552C0496920
DiseaseHereditary Nonpolyposis Colorectal Cancer

MSH6 PIK3CA

1.34e-0329552C1333990
Diseasevery low density lipoprotein cholesterol measurement

PPP2R3A CSNK1G3 MUSK VEGFA

1.41e-03260554EFO_0008317
DiseaseOvarian Carcinoma

MSH6 PIK3CA

1.44e-0330552C0029925
DiseaseAge related macular degeneration

HMCN1 VEGFA

1.44e-0330552C0242383
DiseaseIschemic stroke, von Willebrand factor measurement

KIRREL3 STAB2

1.44e-0330552EFO_0004629, HP_0002140
DiseaseBreast Cancer, Familial

MSH6 PIK3CA

1.44e-0330552C0346153
Diseasemelanoma (is_marker_for)

SETDB1 VEGFA

1.74e-0333552DOID:1909 (is_marker_for)
DiseaseHead and Neck Neoplasms

PIK3CA VEGFA

1.74e-0333552C0018671
Diseasefactor VIII measurement, venous thromboembolism

KIRREL3 STAB2

1.84e-0334552EFO_0004286, EFO_0004630
Diseasetriglyceride measurement, physical activity

GATA4 VEGFA

1.84e-0334552EFO_0003940, EFO_0004530

Protein segments in the cluster

PeptideGeneStartEntry
KAVKAGMPIGCYLAL

EPG5

1011

Q9HCE0
FCLLLGPCMLGKGYH

SLC4A9

266

Q96Q91
AAGAAPMGPQYCVCK

CPNE2

11

Q96FN4
CAGVVGLKMPRYCLF

NPR2

966

P20594
CAGVVGLKMPRYCLF

NPR1

981

P16066
GCCEMQGLIYVIGGI

IPP

431

Q9Y573
GMGIPVGKLALYTAC

ME1

166

P48163
VGKLALYTACGGMNP

ME1

171

P48163
MKLVYCAHCLGVPGA

GPC1

251

P35052
ECMPIKGLGFVLGAY

GPR158

336

Q5T848
VLMKTVCGTPGYCAP

CAMK4

196

Q16566
ACTLGRAGIGLPKMC

FOXL2NB

46

Q6ZUU3
MVPHTYCGKGVCLLT

KCNN1

336

Q92952
YCGKGVCLLTGIMGA

KCNN1

341

Q92952
PGGKAFCMVYAALGL

KCNK7

116

Q9Y2U2
GDMVPHTYCGKGVCL

KCNN3

511

Q9UGI6
GFLCEVPAMIKLACG

OR2C1

176

O95371
KAYCVLVTGPNMGGK

MSH6

1126

P52701
IGLFCGLCTGFVPMY

SLC2A14

151

Q8TDB8
KDLCPGYIGLCPRMS

GRM8

421

O00222
GPCGKYNAMVLELLG

CSNK1G3

106

Q9Y6M4
IYEMGKIAKVCGCPL

PPP2R3A

746

Q06190
LRMLPYGCLSIGDCV

PIK3CA

831

P42336
GCEPGYQLKGRKCMD

HMCN1

5216

Q96RW7
VCNACGLYMKLHGVP

GATA4

291

P43694
EGAGIVLKYIMAGCP

ESPL1

2041

Q14674
KNLIGTYMCICGPGY

FBN1

2266

P35555
DLGVYGMGIPVGKLC

ME2

171

P23368
GMGIPVGKLCLYTAC

ME2

176

P23368
DLGCYGMGIPVGKLA

ME3

196

Q16798
GMGIPVGKLALYTAC

ME3

201

Q16798
CGLCTGFVPMYIGEI

SLC2A3

131

P11169
GLQKRGCCLVLGYMA

KIRREL3

21

Q8IZU9
ISQKMYAVLPCGGIG

HDAC5

771

Q9UQL6
PVLDCGYCLIGGVKM

DLEC1

481

Q9Y238
GYCLIGGVKMTRFIC

DLEC1

486

Q9Y238
MIGFGCKQGIIPTVC

KIF28P

121

B7ZC32
PGKCPVTYGQCLMLN

SLPI

86

P03973
LVCNGLGIYCGMKTL

PTDSS2

251

Q9BVG9
TCIMGVCICVPGYKG

TENM1

606

Q9UKZ4
IGCVVMGLGCFLKSL

SLCO1A2

91

P46721
FCMTGKPGIICVEGF

RWDD2A

186

Q9UIY3
GLLEMKCCPNLTGGY

SEC23A

356

Q15436
MGFHVIYKTPCGLCL

SETDB1

621

Q15047
CMPTGAGKSLCYQLP

RECQL5

51

O94762
MVLGGCPVSYLLLCG

TM2D2

1

Q9BX73
KAGCILCGYLKLTPM

SLC5A2

311

P31639
MAKGYLLLPGCPCLH

TEX37

146

Q96LM6
ANGGCGYVLKPGCMC

PLCH2

726

O75038
GYVLKPGCMCQGVFN

PLCH2

731

O75038
PQGCMYLPGCTIKEI

ARHGAP25

86

P42331
GCKGTIILSMCGYVA

UNC93A

66

Q86WB7
CALNLGVKCPDGYTM

STAB2

46

Q8WWQ8
CCFLIIVGMLGYCGT

TSPAN12

71

O95859
GEKPYECMECGKALG

ZNF124

146

Q15973
GCVASVLGYCLLPMV

YIPF7

201

Q8N8F6
YIFKPSCVPLMRCGG

VEGFA

71

P15692
NMSHVKGGCILCGYL

SLC5A1

306

P13866
CAICLGLAGKPAFMG

SMC5

91

Q8IY18
MVVKGGDGPYKCELC

ZNF44

236

P15621
CAAGALPVTGVCYKM

UGGT1

11

Q9NYU2
LLGVCAVGKPMCLLF

MUSK

641

O15146