Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncarbohydrate binding

HEXB SLC2A8

8.05e-0331092GO:0030246
GeneOntologyBiologicalProcesssingle fertilization

IGSF8 HEXB PLA2G10

8.24e-0520993GO:0007338
GeneOntologyBiologicalProcessfertilization

IGSF8 HEXB PLA2G10

1.63e-0426393GO:0009566
GeneOntologyBiologicalProcessintracellular calcium ion homeostasis

HEXB THADA DHRS7C

4.06e-0435993GO:0006874
GeneOntologyBiologicalProcesscalcium ion homeostasis

HEXB THADA DHRS7C

5.14e-0438993GO:0055074
GeneOntologyBiologicalProcessmaintenance of location

HEXB DHRS7C PLA2G10

5.41e-0439693GO:0051235
GeneOntologyBiologicalProcesslipid storage

HEXB PLA2G10

9.03e-0410592GO:0019915
GeneOntologyBiologicalProcesschemical homeostasis

HEXB THADA DHRS7C PLA2G10

1.32e-03124994GO:0048878
GeneOntologyBiologicalProcessD-glucose transmembrane transport

SLC2A8 DHRS7C

1.78e-0314892GO:1904659
GeneOntologyBiologicalProcesshexose transmembrane transport

SLC2A8 DHRS7C

1.85e-0315192GO:0008645
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

HEXB THADA DHRS7C

1.90e-0361193GO:0030003
GeneOntologyBiologicalProcessmonosaccharide transmembrane transport

SLC2A8 DHRS7C

1.93e-0315492GO:0015749
GeneOntologyBiologicalProcessintracellular monoatomic ion homeostasis

HEXB THADA DHRS7C

2.00e-0362293GO:0006873
GeneOntologyBiologicalProcessinorganic ion homeostasis

HEXB THADA DHRS7C

2.00e-0362293GO:0098771
GeneOntologyBiologicalProcesscarbohydrate transmembrane transport

SLC2A8 DHRS7C

2.29e-0316892GO:0034219
GeneOntologyBiologicalProcesscarbohydrate transport

SLC2A8 DHRS7C

2.79e-0318692GO:0008643
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

HEXB THADA DHRS7C

2.86e-0370593GO:0055080
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

HEXB THADA DHRS7C

3.00e-0371793GO:0050801
GeneOntologyBiologicalProcesslipid homeostasis

THADA PLA2G10

3.58e-0321192GO:0055088
GeneOntologyCellularComponentacrosomal vesicle

HEXB PLA2G10

3.32e-0320692GO:0001669
GeneOntologyCellularComponentlysosome

HEXB SLC2A8 PLA2G10

4.10e-0381193GO:0005764
GeneOntologyCellularComponentlytic vacuole

HEXB SLC2A8 PLA2G10

4.10e-0381193GO:0000323
GeneOntologyCellularComponentvacuole

HEXB SLC2A8 PLA2G10

5.72e-0391393GO:0005773
PathwayREACTOME_SYNTHESIS_OF_PA

ALPP PLA2G10

1.72e-044172MM14583
PathwayREACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS

ALPP PLA2G10

1.47e-0312072MM14585
PathwayREACTOME_METABOLISM_OF_LIPIDS

HEXB ALPP PLA2G10

2.59e-0362073MM15193
PathwayREACTOME_PHOSPHOLIPID_METABOLISM

ALPP PLA2G10

3.86e-0319672MM14591
InteractionCLEC4A interactions

IGSF8 THADA SLC2A8

1.07e-0510393int:CLEC4A
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1-Excitatory_Neuron.Slc17a7.Parm1.Lsamp_(Deep_layer_pyramidal_cells--layer_5)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

C20orf141 PTPRCAP

4.34e-0550926790f78c37288ddf1a80934cae6309b61a929ac6
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGSF8 PTPRCAP

3.41e-041409211e441c3435ad8911ab401ca7d4ae1d3e5fa6eac
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGSF8 PTPRCAP

3.41e-041409294444b92acfad64d811ebb1545dc1dab64473795
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THADA PTPRCAP

4.56e-0416292b877b232f0a879a9058d81ad4730e7846484b7c3
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THADA PTPRCAP

4.56e-04162927384a4dd38ed68ca02a72df6deff4d34c9694ce1
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C20orf141 PTPRCAP

4.68e-04164927c016236f0cea38195c1373ebbd2c0b2b2ec81ad
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C20orf141 PTPRCAP

4.68e-041649207d9252b267cb61c6050fbfa5b440aef1349f673
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.4|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ALPP PTPRCAP

4.73e-04165924d364e1aae41aea483d1311e5e8ef4fc33e30d5e
ToppCellfacs-Lung-24m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IGSF8 HEXB

4.79e-04166927be2b5c62e2be3437ea50b9a473cf9fc7f05e0b1
ToppCellfacs-Lung-24m-Hematologic-myeloid-interstitial_macrophage|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IGSF8 HEXB

4.79e-04166928418b191e7f16cb39301df3ddbfb1bab6c0632d6
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THADA PTPRCAP

4.90e-04168926c758eb120faf06ff72d157b495e399191c79ec9
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THADA PTPRCAP

4.96e-0416992a388e53deac861a185c31e9cceddae7bcb344700
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HEXB PTPRCAP

4.96e-0416992c100a91be9b94bd433a3b172f4a1bfb9d2393003
ToppCellPND03-Immune|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HEXB PTPRCAP

5.20e-04173928543304ae72f781da311deca05871098eabc4a19
ToppCelldroplet-Heart-4Chambers-21m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DHRS7C PTPRCAP

5.26e-0417492f098778ea74012861ec74b425e45776a31f67679
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DHRS7C PTPRCAP

5.26e-0417492ecdff386d7f0bc57c170a2c1f4deae5ba7e431b5
ToppCellfacs-Lung-nan-3m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THADA PTPRCAP

5.50e-04178925ecbea15efd304057aef826ec2f385997bfaf0c9
ToppCellLPS-antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HEXB THADA

5.50e-0417892289d1425c4e57fabcca994b27f9af1c0ce5d5bec
ToppCellfacs-Lung-nan-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THADA PTPRCAP

5.50e-0417892a9a8567d8fdc0fffd612fee16b5b29ef7b1c9307
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEXB PLA2G10

5.63e-0418092a0faed4cf23f6d5e6e8f6b0284cea8a5bd0680a0
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l5|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THADA PTPRCAP

5.63e-0418092d6e69ac2bd619557ef62ada684c37a44dc4e3f41
ToppCelldroplet-Kidney-nan-3m-Hematologic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THADA PTPRCAP

5.69e-041819258d7e76dfaa818aeaef7f129c4472bf5b6563218
ToppCelldroplet-Kidney-nan-3m-Hematologic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THADA PTPRCAP

5.69e-04181925d76e99bf2b5b337041efd3cd33bebbb0637b64e
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEXB PLA2G10

5.69e-041819275340f0c06977c88f9d2e56265f4aa84d706d2c6
ToppCellAT1-AT2_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

ALPP PLA2G10

5.69e-0418192ca23ce4f2c7b684d8ddd0e8619b3b696023d75e3
ToppCelldroplet-Kidney-nan-3m-Hematologic-leukocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THADA PTPRCAP

5.69e-0418192970fc90e27236ee30190f1a02f418a378919c60b
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THADA PTPRCAP

5.81e-0418392c9cb69377883d4579c608ec8b265153fe5290e67
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THADA PTPRCAP

5.88e-0418492cdacb61878e0824b8416bf365d89965797208359
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEXB PLA2G10

5.94e-0418592fd1911b57927c03470f9387962ca9581e5643fb3
ToppCellfacs-Large_Intestine-Distal-3m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEXB PLA2G10

5.94e-04185927a18d525de6f874924bfc61b9666b307da86421a
ToppCellfacs-Large_Intestine-Distal-24m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEXB PLA2G10

5.94e-04185922ecc4b76b3645b65c226c2298bff307cc6479172
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEXB PLA2G10

5.94e-0418592e29079ef09aee62c3e9756341db4e59ca9dbf7ac
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DHRS7C C20orf141

6.07e-04187926f47a80e612b320f571210483e62ff5db2a8ea43
ToppCellAT1-AT2_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

ALPP PLA2G10

6.13e-0418892be710bc957118cf426dd71c2d57e6f1b41c9a467
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEXB PLA2G10

6.13e-0418892bfd3b4f57785596b2bd2c657e0d2d8b0f40ba36d
ToppCellfacs-Large_Intestine-Distal|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEXB PLA2G10

6.26e-04190923964a8390522b61b73235151bb0a2ff36b856867
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-DC3-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ALPP PTPRCAP

6.46e-04193925a4accf3af236ff285942163c45277a80263f421
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-DC3|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ALPP PTPRCAP

6.59e-0419592de60fa0c69c835f0b1d6d2dba1a1acd73246b001
ToppCell(1)_T_cell-(15)_Treg|(1)_T_cell / shred on Cell_type and subtype

THADA PTPRCAP

6.73e-04197926e7723e8b977be35c60cc11ac7cfa4f71339441e
ToppCellASK428-Immune|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

HEXB PTPRCAP

6.80e-0419892777ee3e46943f8ec76ffc0f42be0e2658c0bd57f
ToppCellBiopsy_Control_(H.)-Epithelial-Transitional_AT2|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

ALPP PLA2G10

6.87e-0419992e04a57a55c724091db353e2b3baf84372d788728
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-DC3-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

THADA PTPRCAP

6.87e-04199927271dbeca9aa838b88ad44d00059263a29c0316b
ToppCellGoblet_3|World / shred by cell class for nasal brushing

HEXB PLA2G10

6.87e-04199924229a17a3a6d8855655acc0a1c8704166f8e74c0
Drugglucose-6-P

HEXB SLC2A8 ALPP

2.17e-0436683CID000000208
DrugL-dehydroascorbic acid

SLC2A8 ALPP

4.26e-049082CID000000835
Drug4-nitro-phen-yl

HEXB ALPP

4.55e-049382CID000119211
DrugAC1L9R2Z

HEXB ALPP

1.47e-0316882CID000453624
Drug4-nitrophenol

HEXB ALPP

1.63e-0317782CID000000980
Drugbutyrate

SLC2A8 ALPP PLA2G10

1.88e-0376783CID000000264
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HG-U133A

THADA PTPRCAP

1.92e-03192821400_DN
DrugFluticasone propionate [80474-14-2]; Up 200; 8uM; MCF7; HT_HG-U133A

SLC2A8 PTPRCAP

1.92e-03192824129_UP
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HG-U133A

THADA PTPRCAP

1.92e-03192821971_DN
DrugImipenem [74431-23-5]; Down 200; 13.4uM; HL60; HG-U133A

THADA PTPRCAP

1.96e-03194821724_DN
DrugAlbendazole [54965-21-8]; Down 200; 15uM; HL60; HG-U133A

THADA PTPRCAP

1.96e-03194821547_DN
DrugAjmalicine hydrochloride [4373-34-6]; Down 200; 10.2uM; HL60; HG-U133A

THADA PTPRCAP

1.96e-03194821748_DN
Drug2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A_EA

THADA SLC2A8

1.96e-03194821060_UP
DrugChlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; PC3; HT_HG-U133A

THADA SLC2A8

1.96e-03194821822_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HG-U133A

THADA PTPRCAP

2.00e-03196822035_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HG-U133A

THADA PTPRCAP

2.02e-03197821732_DN
DrugMemantine Hydrochloride [41100-52-1]; Up 200; 18.6uM; MCF7; HT_HG-U133A

SLC2A8 PTPRCAP

2.02e-03197827354_UP
DrugN6-methyladenosine [1867-73-8]; Down 200; 14.2uM; MCF7; HT_HG-U133A

THADA SLC2A8

2.02e-03197825332_DN
DrugNialamide [51-12-7]; Up 200; 13.4uM; PC3; HT_HG-U133A

ALPP PTPRCAP

2.04e-03198823790_UP
Drughaloperidol; Down 200; 10uM; MCF7; HT_HG-U133A

THADA SLC2A8

2.06e-03199826963_DN
DrugZalcitabine [7481-89-2]; Down 200; 19uM; MCF7; HT_HG-U133A

THADA PTPRCAP

2.06e-03199824799_DN
Drug2-propylpentanoic acid; Down 200; 2000uM; MCF7; HG-U133A

THADA SLC2A8

2.06e-0319982346_DN
Drugalpha-Santonin [481-06-1]; Up 200; 16.2uM; PC3; HT_HG-U133A

ALPP PTPRCAP

2.08e-03200823795_UP
DrugLS-63783

HEXB ALPP PLA2G10

2.15e-0380483CID000000231
Drugperiodic acid

HEXB ALPP

2.18e-0320582CID000065185

Protein segments in the cluster

PeptideGeneStartEntry
MGPLPVCLPIMLLLL

PLA2G10

1

O15496
MLGPCMLLLLLLLGL

ALPP

1

P05187
PSLPLLLLLMLGMGC

IGSF8

11

Q969P0
LLLMGLGPLLRACGM

C20orf141

136

Q9NUB4
MLMLPLLLLGISGLL

DHRS7C

6

A6NNS2
MELCGLGLPRPPMLL

HEXB

1

P07686
ALLLGMLCQLLPMQP

THADA

1061

Q6YHU6
MALPCTLGLGMLLAL

PTPRCAP

1

Q14761
VLGCVPPSLMLLLMC

SLC2A8

186

Q9NY64