Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent protein folding chaperone	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	3.22e-08	40	17	4	GO:0140662
GeneOntologyMolecularFunction	protein folding chaperone	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	3.77e-07	73	17	4	GO:0044183
GeneOntologyMolecularFunction	CTP binding	HSP90AA1 HSP90AB1	6.82e-07	2	17	2	GO:0002135
GeneOntologyMolecularFunction	sulfonylurea receptor binding	HSP90AA1 HSP90AB1	2.05e-06	3	17	2	GO:0017098
GeneOntologyMolecularFunction	unfolded protein binding	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	3.38e-06	126	17	4	GO:0051082
GeneOntologyMolecularFunction	UTP binding	HSP90AA1 HSP90AB1	4.09e-06	4	17	2	GO:0002134
GeneOntologyMolecularFunction	disordered domain specific binding	HSP90AA1 HSP90AB1 HSP90AB3P	4.60e-06	39	17	3	GO:0097718
GeneOntologyMolecularFunction	pyrimidine ribonucleotide binding	HSP90AA1 HSP90AB1	6.81e-06	5	17	2	GO:0032557
GeneOntologyMolecularFunction	dATP binding	HSP90AA1 HSP90AB1	6.81e-06	5	17	2	GO:0032564
GeneOntologyMolecularFunction	adenyl deoxyribonucleotide binding	HSP90AA1 HSP90AB1	1.02e-05	6	17	2	GO:0032558
GeneOntologyMolecularFunction	purine deoxyribonucleotide binding	HSP90AA1 HSP90AB1	1.43e-05	7	17	2	GO:0032554
GeneOntologyMolecularFunction	TPR domain binding	HSP90AA1 HSP90AB1	1.90e-05	8	17	2	GO:0030911
GeneOntologyMolecularFunction	deoxyribonucleotide binding	HSP90AA1 HSP90AB1	2.45e-05	9	17	2	GO:0032552
GeneOntologyMolecularFunction	ATP hydrolysis activity	SMC3 HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	2.55e-05	441	17	5	GO:0016887
GeneOntologyMolecularFunction	nitric-oxide synthase regulator activity	HSP90AA1 HSP90AB1	3.06e-05	10	17	2	GO:0030235
GeneOntologyMolecularFunction	pyrimidine nucleotide binding	HSP90AA1 HSP90AB1	3.74e-05	11	17	2	GO:0019103
GeneOntologyMolecularFunction	ATP-dependent activity	SMC3 HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	1.23e-04	614	17	5	GO:0140657
GeneOntologyMolecularFunction	DNA polymerase binding	HSP90AA1 HSP90AB1	1.71e-04	23	17	2	GO:0070182
GeneOntologyMolecularFunction	MHC class II protein complex binding	HSP90AA1 HSP90AB1	2.36e-04	27	17	2	GO:0023026
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	SMC3 HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	3.64e-04	775	17	5	GO:0017111
GeneOntologyMolecularFunction	transmembrane transporter binding	HSP90AA1 ITPR2 HSP90AB1	3.91e-04	172	17	3	GO:0044325
GeneOntologyMolecularFunction	pyrophosphatase activity	SMC3 HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	5.25e-04	839	17	5	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	SMC3 HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	5.28e-04	840	17	5	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	SMC3 HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	5.28e-04	840	17	5	GO:0016818
GeneOntologyMolecularFunction	MHC protein complex binding	HSP90AA1 HSP90AB1	5.49e-04	41	17	2	GO:0023023
GeneOntologyMolecularFunction	protein domain specific binding	SKIL TLN1 HSP90AA1 HSP90AB1 HSP90AB3P	6.36e-04	875	17	5	GO:0019904
GeneOntologyMolecularFunction	tau protein binding	HSP90AA1 HSP90AB1	6.91e-04	46	17	2	GO:0048156
GeneOntologyMolecularFunction	ubiquitin protein ligase binding	HSP90AA1 SLF1 HSP90AB1	2.72e-03	337	17	3	GO:0031625
GeneOntologyMolecularFunction	scaffold protein binding	HSP90AA1 ITPR2	2.79e-03	93	17	2	GO:0097110
GeneOntologyMolecularFunction	ubiquitin-like protein ligase binding	HSP90AA1 SLF1 HSP90AB1	3.22e-03	358	17	3	GO:0044389
GeneOntologyMolecularFunction	histone deacetylase binding	HSP90AA1 HSP90AB1	6.81e-03	147	17	2	GO:0042826
GeneOntologyMolecularFunction	cytoskeletal protein binding	SMC3 TLN1 HSP90AA1 HSP90AB1	1.22e-02	1099	17	4	GO:0008092
GeneOntologyBiologicalProcess	telomerase holoenzyme complex assembly	HSP90AA1 HSP90AB1	9.57e-06	6	17	2	GO:1905323
GeneOntologyBiologicalProcess	cellular response to heat	HSP90AA1 HSP90AB1 HSP90AB3P	3.81e-05	81	17	3	GO:0034605
GeneOntologyBiologicalProcess	protein folding	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	4.16e-05	246	17	4	GO:0006457
GeneOntologyBiologicalProcess	positive regulation of cell size	HSP90AA1 HSP90AB1	1.08e-04	19	17	2	GO:0045793
GeneOntologyBiologicalProcess	response to heat	HSP90AA1 HSP90AB1 HSP90AB3P	1.26e-04	121	17	3	GO:0009408
GeneOntologyBiologicalProcess	chaperone-mediated protein complex assembly	HSP90AA1 HSP90AB1	1.90e-04	25	17	2	GO:0051131
GeneOntologyBiologicalProcess	telomere maintenance	HSP90AA1 SLF1 HSP90AB1	3.32e-04	168	17	3	GO:0000723
GeneOntologyBiologicalProcess	mitotic sister chromatid cohesion	SMC3 SLF1	3.96e-04	36	17	2	GO:0007064
GeneOntologyBiologicalProcess	telomere organization	HSP90AA1 SLF1 HSP90AB1	5.44e-04	199	17	3	GO:0032200
GeneOntologyBiologicalProcess	response to temperature stimulus	HSP90AA1 HSP90AB1 HSP90AB3P	6.19e-04	208	17	3	GO:0009266
GeneOntologyCellularComponent	dendritic growth cone	HSP90AA1 HSP90AB1	3.61e-05	12	16	2	GO:0044294
GeneOntologyCellularComponent	dendrite terminus	HSP90AA1 HSP90AB1	1.04e-04	20	16	2	GO:0044292
GeneOntologyCellularComponent	sperm plasma membrane	HSP90AA1 HSP90AB1	1.26e-04	22	16	2	GO:0097524
GeneOntologyCellularComponent	mitotic spindle pole	ASPM SMC3	4.87e-04	43	16	2	GO:0097431
GeneOntologyCellularComponent	axonal growth cone	HSP90AA1 HSP90AB1	5.33e-04	45	16	2	GO:0044295
GeneOntologyCellularComponent	brush border membrane	HSP90AA1 HSP90AB1	1.80e-03	83	16	2	GO:0031526
GeneOntologyCellularComponent	inclusion body	SLF1 HSP90AB1	2.12e-03	90	16	2	GO:0016234
GeneOntologyCellularComponent	pigment granule	HSP90AA1 HSP90AB1	3.31e-03	113	16	2	GO:0048770
GeneOntologyCellularComponent	melanosome	HSP90AA1 HSP90AB1	3.31e-03	113	16	2	GO:0042470
GeneOntologyCellularComponent	ficolin-1-rich granule lumen	HSP90AA1 HSP90AB1	3.97e-03	124	16	2	GO:1904813
GeneOntologyCellularComponent	cell projection membrane	TLN1 HSP90AA1 HSP90AB1	3.99e-03	431	16	3	GO:0031253
GeneOntologyCellularComponent	perinuclear region of cytoplasm	TNFSF13B HSP90AA1 HSP90AB1 HSP90AB3P	4.68e-03	934	16	4	GO:0048471
GeneOntologyCellularComponent	apical plasma membrane	ASPM HSP90AA1 HSP90AB1	5.61e-03	487	16	3	GO:0016324
GeneOntologyCellularComponent	brush border	HSP90AA1 HSP90AB1	5.90e-03	152	16	2	GO:0005903
GeneOntologyCellularComponent	secretory granule	SKIL HSP90AA1 ITPR2 HSP90AB1	6.27e-03	1014	16	4	GO:0030141
GeneOntologyCellularComponent	ficolin-1-rich granule	HSP90AA1 HSP90AB1	8.62e-03	185	16	2	GO:0101002
GeneOntologyCellularComponent	apical part of cell	ASPM HSP90AA1 HSP90AB1	9.61e-03	592	16	3	GO:0045177
GeneOntologyCellularComponent	mitotic spindle	ASPM SMC3	1.01e-02	201	16	2	GO:0072686
GeneOntologyCellularComponent	spindle pole	ASPM SMC3	1.05e-02	205	16	2	GO:0000922
HumanPheno	Hooded eyelid	SMC3 CDC42BPB	1.15e-05	6	5	2	HP:0030820
Domain	Heat_shock_protein_90_CS	HSP90AA1 HSP90AB1	1.81e-06	3	15	2	IPR019805
Domain	DUF3496	ANKRD26 ANKRD18A	1.81e-06	3	15	2	IPR021885
Domain	DUF3496	ANKRD26 ANKRD18A	1.81e-06	3	15	2	PF12001
Domain	HSP90	HSP90AA1 HSP90AB1	3.61e-06	4	15	2	PF00183
Domain	Hsp90_N	HSP90AA1 HSP90AB1	3.61e-06	4	15	2	IPR020575
Domain	HSP90	HSP90AA1 HSP90AB1	3.61e-06	4	15	2	PS00298
Domain	Hsp90_fam	HSP90AA1 HSP90AB1	3.61e-06	4	15	2	IPR001404
Domain	CNH	CDC42BPB MAP4K1	5.45e-05	14	15	2	SM00036
Domain	CNH_dom	CDC42BPB MAP4K1	6.28e-05	15	15	2	IPR001180
Domain	CNH	CDC42BPB MAP4K1	6.28e-05	15	15	2	PS50219
Domain	CNH	CDC42BPB MAP4K1	6.28e-05	15	15	2	PF00780
Domain	HATPase_c	HSP90AA1 HSP90AB1	9.14e-05	18	15	2	SM00387
Domain	HATPase_c	HSP90AA1 HSP90AB1	1.02e-04	19	15	2	PF02518
Domain	-	HSP90AA1 HSP90AB1	1.13e-04	20	15	2	3.30.565.10
Domain	HATPase_C	HSP90AA1 HSP90AB1	1.25e-04	21	15	2	IPR003594
Domain	Ribosomal_S5_D2-typ_fold	HSP90AA1 HSP90AB1	3.33e-04	34	15	2	IPR020568
Domain	Ank_2	ANKRD26 ANKRD18A SLF1	6.18e-04	215	15	3	PF12796
Domain	Ank	ANKRD26 ANKRD18A SLF1	7.33e-04	228	15	3	PF00023
Domain	-	ANKRD26 ANKRD18A SLF1	9.35e-04	248	15	3	1.25.40.20
Domain	ANK	ANKRD26 ANKRD18A SLF1	9.68e-04	251	15	3	SM00248
Domain	ANK_REPEAT	ANKRD26 ANKRD18A SLF1	9.91e-04	253	15	3	PS50088
Domain	Ankyrin_rpt-contain_dom	ANKRD26 ANKRD18A SLF1	1.00e-03	254	15	3	IPR020683
Domain	ANK_REP_REGION	ANKRD26 ANKRD18A SLF1	1.00e-03	254	15	3	PS50297
Domain	Ankyrin_rpt	ANKRD26 ANKRD18A SLF1	1.10e-03	262	15	3	IPR002110
Pathway	REACTOME_SEMAPHORIN_INTERACTIONS	TLN1 HSP90AA1 HSP90AB1	9.59e-06	51	12	3	MM14967
Pathway	REACTOME_UPTAKE_AND_FUNCTION_OF_DIPHTHERIA_TOXIN	HSP90AA1 HSP90AB1	9.95e-06	6	12	2	M27430
Pathway	REACTOME_HSF1_ACTIVATION	HSP90AA1 HSP90AB1	1.85e-05	8	12	2	MM14950
Pathway	REACTOME_SEMAPHORIN_INTERACTIONS	TLN1 HSP90AA1 HSP90AB1	1.91e-05	64	12	3	M7923
Pathway	REACTOME_ATTENUATION_PHASE	HSP90AA1 HSP90AB1	5.15e-05	13	12	2	MM14952
Pathway	REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION	HSP90AA1 HSP90AB1	6.01e-05	14	12	2	MM15029
Pathway	REACTOME_RESPIRATORY_SYNCYTIAL_VIRUS_RSV_GENOME_REPLICATION_TRANSCRIPTION_AND_TRANSLATION	HSP90AA1 HSP90AB1	7.92e-05	16	12	2	M48235
Pathway	REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION	HSP90AA1 HSP90AB1	7.92e-05	16	12	2	M16498
Pathway	REACTOME_CHAPERONE_MEDIATED_AUTOPHAGY	HSP90AA1 HSP90AB1	1.52e-04	22	12	2	M27937
Pathway	REACTOME_RHOBTB2_GTPASE_CYCLE	HSP90AA1 HSP90AB1	1.66e-04	23	12	2	M41723
Pathway	REACTOME_HSF1_DEPENDENT_TRANSACTIVATION	HSP90AA1 HSP90AB1	1.66e-04	23	12	2	MM14953
Pathway	REACTOME_RHOBTB2_GTPASE_CYCLE	HSP90AA1 HSP90AB1	1.97e-04	25	12	2	MM15606
Pathway	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS	HSP90AA1 ITPR2 HSP90AB1	2.10e-04	143	12	3	M27107
Pathway	REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION	SMC3 HSP90AA1 HSP90AB1	2.37e-04	149	12	3	M27888
Pathway	REACTOME_ATTENUATION_PHASE	HSP90AA1 HSP90AB1	2.48e-04	28	12	2	M27254
Pathway	REACTOME_UPTAKE_AND_ACTIONS_OF_BACTERIAL_TOXINS	HSP90AA1 HSP90AB1	2.66e-04	29	12	2	M27431
Pathway	REACTOME_HSF1_ACTIVATION	HSP90AA1 HSP90AB1	3.05e-04	31	12	2	M27252
Pathway	REACTOME_DDX58_IFIH1_MEDIATED_INDUCTION_OF_INTERFERON_ALPHA_BETA	HSP90AA1 HSP90AB1	3.46e-04	33	12	2	MM14666
Pathway	REACTOME_RHO_GTPASE_CYCLE	ANKRD26 CDC42BPB HSP90AA1 HSP90AB1	3.76e-04	439	12	4	MM15595
Pathway	REACTOME_RHOBTB_GTPASE_CYCLE	HSP90AA1 HSP90AB1	3.89e-04	35	12	2	M41738
Pathway	REACTOME_RHO_GTPASE_CYCLE	ANKRD26 CDC42BPB HSP90AA1 HSP90AB1	4.14e-04	450	12	4	M27078
Pathway	REACTOME_RHOBTB_GTPASE_CYCLE	HSP90AA1 HSP90AB1	4.35e-04	37	12	2	MM15683
Pathway	REACTOME_HSF1_DEPENDENT_TRANSACTIVATION	HSP90AA1 HSP90AB1	4.59e-04	38	12	2	M27255
Pathway	SIG_BCR_SIGNALING_PATHWAY	MAP4K1 ITPR2	6.73e-04	46	12	2	M8626
Pathway	REACTOME_ESR_MEDIATED_SIGNALING	SMC3 HSP90AA1 HSP90AB1	7.43e-04	220	12	3	M27794
Pathway	REACTOME_HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR_IN_THE_PRESENCE_OF_LIGAND	HSP90AA1 HSP90AB1	8.60e-04	52	12	2	MM14949
Pathway	REACTOME_HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR_IN_THE_PRESENCE_OF_LIGAND	HSP90AA1 HSP90AB1	1.03e-03	57	12	2	M27251
Pathway	WP_15Q11Q13_COPY_NUMBER_VARIATION	CDC42BPB SLF1	1.11e-03	59	12	2	M48104
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	TLN1 HSP90AA1 HSP90AB1	1.22e-03	261	12	3	MM15676
Pathway	KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY	HSP90AA1 HSP90AB1	1.22e-03	62	12	2	M15569
Pathway	REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION	HSP90AA1 HSP90AB1	1.26e-03	63	12	2	MM15613
Pathway	PID_VEGFR1_2_PATHWAY	HSP90AA1 HSP90AB1	1.51e-03	69	12	2	M237
Pathway	REACTOME_BACTERIAL_INFECTION_PATHWAYS	HSP90AA1 HSP90AB1	1.60e-03	71	12	2	M48033
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	ANKRD26 CDC42BPB HSP90AA1 HSP90AB1	1.64e-03	649	12	4	MM15690
Pathway	REACTOME_THE_ROLE_OF_GTSE1_IN_G2_M_PROGRESSION_AFTER_G2_CHECKPOINT	HSP90AA1 HSP90AB1	1.69e-03	73	12	2	MM15491
Pathway	PID_AVB3_INTEGRIN_PATHWAY	TLN1 HSP90AA1	1.73e-03	74	12	2	M160
Pathway	REACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS	SMC3 HSP90AA1 HSP90AB1	1.75e-03	296	12	3	M27869
Pathway	REACTOME_THE_ROLE_OF_GTSE1_IN_G2_M_PROGRESSION_AFTER_G2_CHECKPOINT	HSP90AA1 HSP90AB1	1.97e-03	79	12	2	M27743
Pathway	REACTOME_DDX58_IFIH1_MEDIATED_INDUCTION_OF_INTERFERON_ALPHA_BETA	HSP90AA1 HSP90AB1	2.12e-03	82	12	2	M1002
Pathway	KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION	HSP90AA1 HSP90AB1	2.28e-03	85	12	2	M3578
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	ANKRD26 CDC42BPB HSP90AA1 HSP90AB1	2.40e-03	720	12	4	M41838
Pathway	KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION	HSP90AA1 HSP90AB1	2.44e-03	88	12	2	M16004
Pathway	KEGG_PROSTATE_CANCER	HSP90AA1 HSP90AB1	2.50e-03	89	12	2	M13191
Pathway	REACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS	HSP90AA1 HSP90AB1	2.66e-03	92	12	2	MM14951
Pathway	REACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS	HSP90AA1 HSP90AB1	3.20e-03	101	12	2	M27253
Pathway	REACTOME_SIGNALING_BY_VEGF	HSP90AA1 ITPR2	3.52e-03	106	12	2	M27077
Pathway	KEGG_OOCYTE_MEIOSIS	SMC3 ITPR2	3.99e-03	113	12	2	M16817
Pathway	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS	HSP90AA1 HSP90AB1	4.06e-03	114	12	2	MM14814
Pathway	REACTOME_RESPIRATORY_SYNCYTIAL_VIRUS_INFECTION_PATHWAY	HSP90AA1 HSP90AB1	4.49e-03	120	12	2	M48233
Pathway	REACTOME_SARS_COV_2_ACTIVATES_MODULATES_INNATE_AND_ADAPTIVE_IMMUNE_RESPONSES	HSP90AA1 HSP90AB1	4.93e-03	126	12	2	M45009
Pathway	REACTOME_ESR_MEDIATED_SIGNALING	HSP90AA1 HSP90AB1	5.48e-03	133	12	2	MM15529
Pathway	WP_NRF2_PATHWAY	HSP90AA1 HSP90AB1	6.14e-03	141	12	2	M39454
Pathway	REACTOME_POTENTIAL_THERAPEUTICS_FOR_SARS	HSP90AA1 HSP90AB1	7.28e-03	154	12	2	M39007
Pathway	REACTOME_AUTOPHAGY	HSP90AA1 HSP90AB1	7.65e-03	158	12	2	M27935
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	TLN1 HSP90AA1 HSP90AB1	7.77e-03	502	12	3	MM14537
Pathway	REACTOME_MUSCLE_CONTRACTION	TLN1 ITPR2	8.32e-03	165	12	2	MM15026
Pathway	REACTOME_MITOTIC_G2_G2_M_PHASES	HSP90AA1 HSP90AB1	1.03e-02	184	12	2	MM15145
Pathway	REACTOME_CELL_CYCLE_MITOTIC	SMC3 HSP90AA1 HSP90AB1	1.05e-02	561	12	3	M5336
Pathway	REACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS	HSP90AA1 HSP90AB1	1.10e-02	191	12	2	MM15586
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	TLN1 HSP90AA1 HSP90AB1	1.13e-02	575	12	3	M29853
Pubmed	The HSP90 family of genes in the human genome: insights into their divergence and evolution.	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	7.08e-11	16	17	4	16269234
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	SMC3 HSP90AA5P TNFSF13B TLN1 HSP90AA1 HSP90AB1 HSP90AB3P	7.79e-08	847	17	7	35235311
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	SMC3 HSP90AA5P TLN1 HSP90AA1 HSP90AB1 HSP90AB3P	1.43e-07	538	17	6	28524877
Pubmed	Expression of hsp90 and cyclin D1 in human breast cancer.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	10376793
Pubmed	HSP90 expression and early recurrence in gastroenteropancreatic neuroendocrine tumors: Potential for a novel therapeutic target.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	33080545
Pubmed	Heat shock protein 90 facilitates SARS-CoV-2 structural protein-mediated virion assembly and promotes virus-induced pyroptosis.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	37011862
Pubmed	Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	33179566
Pubmed	Translational reprogramming in response to accumulating stressors ensures critical threshold levels of Hsp90 for mammalian life.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	36270993
Pubmed	Hsp90 regulation of fibroblast activation in pulmonary fibrosis.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	28239659
Pubmed	Regulation of embryonic stem cell pluripotency by heat shock protein 90.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	22696450
Pubmed	Despite their structural similarities, the cytosolic isoforms of human Hsp90 show different behaviour in thermal unfolding due to their conformation: An FTIR study.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	37028636
Pubmed	Proliferation, migration, and resistance to oxidative and thermal stresses of HT1080 cells with knocked out genes encoding Hsp90α and Hsp90β.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	37406487
Pubmed	Expression and therapeutic relevance of heat-shock protein 90 in pancreatic endocrine tumors.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	22194440
Pubmed	Circadian expression of 86- and 84-kDa heat shock proteins in the mouse suprachiasmatic nucleus.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	18480550
Pubmed	Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	22895790
Pubmed	Mitochondrial heat shock protein-90 modulates vascular smooth muscle cell survival and the vascular injury response in vivo.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	22841823
Pubmed	Hsp90 is cleaved by reactive oxygen species at a highly conserved N-terminal amino acid motif.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	22848402
Pubmed	Expression of Hsp90 chaperone [corrected] proteins in human tumor tissue.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	19576239
Pubmed	A mouse tumor-specific transplantation antigen is a heat shock-related protein.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	3458168
Pubmed	Mechanism of dimer formation of the 90-kDa heat-shock protein.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	7588731
Pubmed	Substitution of only two residues of human Hsp90alpha causes impeded dimerization of Hsp90beta.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	18347946
Pubmed	Murine 86- and 84-kDa heat shock proteins, cDNA sequences, chromosome assignments, and evolutionary origins.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	2925609
Pubmed	Heat shock protein 90 overexpression independently predicts inferior disease-free survival with differential expression of the alpha and beta isoforms in gastrointestinal stromal tumors.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	19047110
Pubmed	Heat-shock proteins, Hsp84 and Hsp86, of mice and men: two related genes encode formerly identified tumour-specific transplantation antigens.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	2469626
Pubmed	Conserved conformational changes in the ATPase cycle of human Hsp90.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	18400751
Pubmed	Inhibition of RPE cell sterile inflammatory responses and endotoxin-induced uveitis by a cell-impermeable HSP90 inhibitor.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	22019372
Pubmed	Heat shock protein HSP86 expression during mouse embryo development, especially in the germ-line.	HSP90AA1 HSP90AB1	2.25e-07	2	17	2	12136260
Pubmed	Conformational diversity in the TPR domain-mediated interaction of protein phosphatase 5 with Hsp90.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	16531226
Pubmed	Heat Shock Protein 90 Family Isoforms as Prognostic Biomarkers and Their Correlations with Immune Infiltration in Breast Cancer.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	33145341
Pubmed	Molecular recognition via coupled folding and binding in a TPR domain.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	15713458
Pubmed	Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	19996089
Pubmed	HSP-enriched properties of extracellular vesicles involve survival of metastatic oral cancer cells.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	29768689
Pubmed	Two human 90-kDa heat shock proteins are phosphorylated in vivo at conserved serines that are phosphorylated in vitro by casein kinase II.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	2492519
Pubmed	Conformational activation of a basic helix-loop-helix protein (MyoD1) by the C-terminal region of murine HSP90 (HSP84).	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	1406681
Pubmed	Mammalian CHORD-containing protein 1 is a novel heat shock protein 90-interacting protein.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	15642353
Pubmed	Mutations that increase both Hsp90 ATPase activity in vitro and Hsp90 drug resistance in vivo.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	20226818
Pubmed	Hsp90 activity is necessary to acquire a proper neuronal polarization.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	24286867
Pubmed	Hsp90 regulates the activity of wild type p53 under physiological and elevated temperatures.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	15358771
Pubmed	The significance of HSP90AA1, HSP90AB1 and HSP90B1 gene polymorphisms in a Turkish population with non-small cell lung cancer.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	24511009
Pubmed	Modulation of Akt kinase activity by binding to Hsp90.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	10995457
Pubmed	Regulation of cytosolic phospholipase A2alpha by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	18550790
Pubmed	Chaperone ligand-discrimination by the TPR-domain protein Tah1.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	18412542
Pubmed	Interaction of pro-apoptotic protein HGTD-P with heat shock protein 90 is required for induction of mitochondrial apoptotic cascades.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	16698020
Pubmed	N-terminal domain of human Hsp90 triggers binding to the cochaperone p23.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	21183720
Pubmed	Synergistic role of HSP90α and HSP90β to promote myofibroblast persistence in lung fibrosis.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	29386344
Pubmed	Hsp90 stabilizes Cdc25A and counteracts heat shock-mediated Cdc25A degradation and cell-cycle attenuation in pancreatic carcinoma cells.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	22843495
Pubmed	HSP90 affects the stability of BMAL1 and circadian gene expression.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	24682203
Pubmed	HSP90 regulates cell survival via inositol hexakisphosphate kinase-2.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	18195352
Pubmed	Mammalian heat shock factor 1 is essential for oocyte meiosis and directly regulates Hsp90alpha expression.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	19158073
Pubmed	Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells.	HSP90AA1 HSP90AB1	6.74e-07	3	17	2	22849407
Pubmed	HSP90 promotes radioresistance of cervical cancer cells via reducing FBXO6-mediated CD147 polyubiquitination.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	35043518
Pubmed	Stabilization of Notch1 by the Hsp90 Chaperone Is Crucial for T-Cell Leukemogenesis.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	28143869
Pubmed	Identification of HSP90 as a new GABARAPL1 (GEC1)-interacting protein.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	22120110
Pubmed	Functional requirement of p23 and Hsp90 in telomerase complexes.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	10197982
Pubmed	Integrative proteomics reveals the role of E3 ubiquitin ligase SYVN1 in hepatocellular carcinoma metastasis.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	34196494
Pubmed	Hsp90B enhances MAST1-mediated cisplatin resistance by protecting MAST1 from proteosomal degradation.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	31449053
Pubmed	Interaction of HSP90 to N-WASP leads to activation and protection from proteasome-dependent degradation.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	15791211
Pubmed	A heat-shock protein axis regulates VEGFR2 proteolysis, blood vessel development and repair.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	23139789
Pubmed	Hsp90 regulates activation of interferon regulatory factor 3 and TBK-1 stabilization in Sendai virus-infected cells.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	16394098
Pubmed	REV-ERBα influences the stability and nuclear localization of the glucocorticoid receptor.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	27686098
Pubmed	Curcumin inhibits nuclear localization of telomerase by dissociating the Hsp90 co-chaperone p23 from hTERT.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	19751963
Pubmed	Hsp90 regulates p50(cdc37) function during the biogenesis of the activeconformation of the heme-regulated eIF2 alpha kinase.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	11036079
Pubmed	Hsp90-Akt phosphorylates ASK1 and inhibits ASK1-mediated apoptosis.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	15782121
Pubmed	Extracellular heat shock protein 90 binding to TGFβ receptor I participates in TGFβ-mediated collagen production in myocardial fibroblasts.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	27418101
Pubmed	Evidence that peroxisome proliferator-activated receptor alpha is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	12482853
Pubmed	Hsp90 interactions and acylation target the G protein Galpha 12 but not Galpha 13 to lipid rafts.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	12117999
Pubmed	Combination of pan-histone deacetylase inhibitor and autophagy inhibitor exerts superior efficacy against triple-negative human breast cancer cells.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	22367781
Pubmed	Exosomal circSHKBP1 promotes gastric cancer progression via regulating the miR-582-3p/HUR/VEGF axis and suppressing HSP90 degradation.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	32600329
Pubmed	Involvement of heat-shock protein 90 in the interleukin-6-mediated signaling pathway through STAT3.	HSP90AA1 HSP90AB1	1.35e-06	4	17	2	12559950
Pubmed	Defining the Na+/H+ exchanger NHE1 interactome in triple-negative breast cancer cells.	TLN1 HSP90AA1 HSP90AB1	1.45e-06	46	17	3	27751915
Pubmed	A mitochondrial SCF-FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease.	HSP90AA1 HSP90AB1 HSP90AB3P	1.99e-06	51	17	3	36896912
Pubmed	Interactome of the Autoimmune Risk Protein ANKRD55.	SMC3 TLN1 HSP90AA1 HSP90AB1	2.24e-06	197	17	4	31620119
Pubmed	The mammalian CHORD-containing protein melusin is a stress response protein interacting with Hsp90 and Sgt1.	HSP90AA1 HSP90AB1	2.25e-06	5	17	2	18474241
Pubmed	17-AAG, an Hsp90 inhibitor, causes kinetochore defects: a novel mechanism by which 17-AAG inhibits cell proliferation.	HSP90AA1 HSP90AB1	2.25e-06	5	17	2	16501598
Pubmed	MafG controls the hypoxic response of cells by accumulating HIF-1alpha in the nuclei.	HSP90AA1 HSP90AB1	2.25e-06	5	17	2	18538669
Pubmed	Chaperoning checkpoint kinase 1 (Chk1), an Hsp90 client, with purified chaperones.	HSP90AA1 HSP90AB1	2.25e-06	5	17	2	16330544
Pubmed	HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor.	HSP90AA1 HSP90AB1	2.25e-06	5	17	2	15916966
Pubmed	Hsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagy.	HSP90AA1 HSP90AB1	2.25e-06	5	17	2	21855797
Pubmed	Enhanced interaction between Hsp90 and raptor regulates mTOR signaling upon T cell activation.	HSP90AA1 HSP90AB1	2.25e-06	5	17	2	19586661
Pubmed	Interaction of Hsp90 with ribosomal proteins protects from ubiquitination and proteasome-dependent degradation.	HSP90AA1 HSP90AB1	2.25e-06	5	17	2	16314389
Pubmed	Inhibition of Hsp90 via 17-DMAG induces apoptosis in a p53-dependent manner to prevent medulloblastoma.	HSP90AA1 HSP90AB1	2.25e-06	5	17	2	19805107
Pubmed	A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin.	HSP90AA1 HSP90AB1	2.25e-06	5	17	2	9083006
Pubmed	Hsp90/p50cdc37 is required for mixed-lineage kinase (MLK) 3 signaling.	HSP90AA1 HSP90AB1	2.25e-06	5	17	2	15001580
Pubmed	Celastrol inhibits Hsp90 chaperoning of steroid receptors by inducing fibrillization of the Co-chaperone p23.	HSP90AA1 HSP90AB1	2.25e-06	5	17	2	19996313
Pubmed	Middle domain of human Hsp90 isoforms differentially binds Aha1 in human cells and alters Hsp90 activity in yeast.	HSP90AA1 HSP90AB1	2.25e-06	5	17	2	25486457
Pubmed	A screen for deubiquitinating enzymes involved in the G₂/M checkpoint identifies USP50 as a regulator of HSP90-dependent Wee1 stability.	HSP90AA1 HSP90AB1	2.25e-06	5	17	2	20930503
Pubmed	GCUNC45 is the first Hsp90 co-chaperone to show alpha/beta isoform specificity.	HSP90AA1 HSP90AB1	2.25e-06	5	17	2	18285346
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	ANKRD26 CDC42BPB TLN1 HSP90AA1 HSP90AB1	3.14e-06	497	17	5	23414517
Pubmed	Defective Tibetan PHD2 binding to p23 links high altitude adaption to altered oxygen sensing.	HSP90AA1 HSP90AB1	3.37e-06	6	17	2	24711448
Pubmed	Mixed Hsp90-cochaperone complexes are important for the progression of the reaction cycle.	HSP90AA1 HSP90AB1	3.37e-06	6	17	2	21170051
Pubmed	Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53.	HSP90AA1 HSP90AB1	3.37e-06	6	17	2	11707401
Pubmed	URI is required to maintain intestinal architecture during ionizing radiation.	HSP90AA1 HSP90AB1	3.37e-06	6	17	2	31147493
Pubmed	Structural basis for phosphorylation-dependent recruitment of Tel2 to Hsp90 by Pih1.	HSP90AA1 HSP90AB1	3.37e-06	6	17	2	24794838
Pubmed	Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70.	HSP90AA1 HSP90AB1	3.37e-06	6	17	2	9261129
Pubmed	Heat shock induces rapid resorption of primary cilia.	HSP90AA1 HSP90AB1	3.37e-06	6	17	2	22718348
Pubmed	The Inhibition of Heat Shock Protein 90 Facilitates the Degradation of Poly-Alanine Expanded Poly (A) Binding Protein Nuclear 1 via the Carboxyl Terminus of Heat Shock Protein 70-Interacting Protein.	HSP90AA1 HSP90AB1	3.37e-06	6	17	2	26414348
Pubmed	Targeting GRP78-dependent AR-V7 protein degradation overcomes castration-resistance in prostate cancer therapy.	HSP90AA1 HSP90AB1	3.37e-06	6	17	2	32206096
Pubmed	Regulation of Nod1 by Hsp90 chaperone complex.	HSP90AA1 HSP90AB1	3.37e-06	6	17	2	16083881
Pubmed	Pink1 Parkinson mutations, the Cdc37/Hsp90 chaperones and Parkin all influence the maturation or subcellular distribution of Pink1.	HSP90AA1 HSP90AB1	3.37e-06	6	17	2	18003639
Pubmed	Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex.	HSP90AA1 HSP90AB1	3.37e-06	6	17	2	30382094
Interaction	CDKL4 interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	2.47e-10	13	17	4	int:CDKL4
Interaction	UNC45B interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	2.51e-09	22	17	4	int:UNC45B
Interaction	CCDC117 interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	5.12e-09	26	17	4	int:CCDC117
Interaction	STK35 interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	9.37e-09	30	17	4	int:STK35
Interaction	RPS6KA4 interactions	HSP90AA5P MAP4K1 HSP90AA1 HSP90AB1 HSP90AB3P	1.60e-08	100	17	5	int:RPS6KA4
Interaction	SRMS interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	3.11e-08	40	17	4	int:SRMS
Interaction	AURKC interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	4.19e-08	43	17	4	int:AURKC
Interaction	SGK2 interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	4.19e-08	43	17	4	int:SGK2
Interaction	TSSK6 interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	6.04e-08	47	17	4	int:TSSK6
Interaction	MAP2K2 interactions	SMC3 HSP90AA5P MAP4K1 HSP90AA1 HSP90AB1 HSP90AB3P	7.11e-08	278	17	6	int:MAP2K2
Interaction	MAP3K6 interactions	ASPM HSP90AA5P TNFSF13B HSP90AA1	8.45e-08	51	17	4	int:MAP3K6
Interaction	CDK4 interactions	ASPM SMC3 HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	9.51e-08	292	17	6	int:CDK4
Interaction	GBP2 interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	1.07e-07	54	17	4	int:GBP2
Interaction	AMHR2 interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	1.24e-07	56	17	4	int:AMHR2
Interaction	ITK interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	1.88e-07	62	17	4	int:ITK
Interaction	SMYD3 interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	3.25e-07	71	17	4	int:SMYD3
Interaction	PDIK1L interactions	HSP90AA5P HSP90AA1 HSP90AB1	6.57e-07	21	17	3	int:PDIK1L
Interaction	AKT3 interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	6.73e-07	85	17	4	int:AKT3
Interaction	STK32C interactions	ASPM HSP90AA5P HSP90AA1 HSP90AB1	7.39e-07	87	17	4	int:STK32C
Interaction	MYLK4 interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	8.47e-07	90	17	4	int:MYLK4
Interaction	GUCY2D interactions	HSP90AA5P HSP90AA1 HSP90AB3P	8.74e-07	23	17	3	int:GUCY2D
Interaction	INSRR interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	9.66e-07	93	17	4	int:INSRR
Interaction	PTGES3 interactions	HSP90AA5P CDC42BPB MAP4K1 HSP90AA1 HSP90AB1 HSP90AB3P	1.02e-06	437	17	6	int:PTGES3
Interaction	GRK7 interactions	HSP90AA1 HSP90AB1 HSP90AB3P	1.13e-06	25	17	3	int:GRK7
Interaction	ANKK1 interactions	SMC3 HSP90AA1 HSP90AB1	2.21e-06	31	17	3	int:ANKK1
Interaction	PPP5C interactions	HSP90AA5P CDC42BPB MAP4K1 HSP90AA1 HSP90AB1	2.34e-06	272	17	5	int:PPP5C
Interaction	CDK15 interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	2.42e-06	117	17	4	int:CDK15
Interaction	STK33 interactions	TLN1 HSP90AA1 HSP90AB1	4.13e-06	38	17	3	int:STK33
Interaction	BTK interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	5.69e-06	145	17	4	int:BTK
Interaction	HSP90AB1 interactions	HSP90AA5P MAP4K1 TLN1 HSP90AA1 GIPC2 HSP90AB1 HSP90AB3P	6.95e-06	960	17	7	int:HSP90AB1
Interaction	AGO3 interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	7.04e-06	153	17	4	int:AGO3
Interaction	CDK13 interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	7.04e-06	153	17	4	int:CDK13
Interaction	STIP1 interactions	SMC3 HSP90AA5P MAP4K1 TLN1 HSP90AA1 HSP90AB1 HSP90AB3P	9.46e-06	1006	17	7	int:STIP1
Interaction	PINK1 interactions	SMC3 HSP90AA5P TLN1 HSP90AA1 HSP90AB1 HSP90AB3P	1.29e-05	679	17	6	int:PINK1
Interaction	CDK11A interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	1.34e-05	180	17	4	int:CDK11A
Interaction	SBK2 interactions	HSP90AA1 HSP90AB1	1.40e-05	7	17	2	int:SBK2
Interaction	MAP3K11 interactions	MAP4K1 HSP90AA1 HSP90AB1	1.66e-05	60	17	3	int:MAP3K11
Interaction	LYN interactions	ANKRD26 CDC42BPB MAP4K1 HSP90AA1 HSP90AB1 HSP90AB3P	1.80e-05	720	17	6	int:LYN
Interaction	SLC17A1 interactions	HSP90AA1 HSP90AB1	1.87e-05	8	17	2	int:SLC17A1
Interaction	NLRC3 interactions	HSP90AA1 HSP90AB1	1.87e-05	8	17	2	int:NLRC3
Interaction	PSKH2 interactions	HSP90AA5P HSP90AA1 HSP90AB1	2.31e-05	67	17	3	int:PSKH2
Interaction	ZNF541 interactions	HSP90AA1 HSP90AB1	2.40e-05	9	17	2	int:ZNF541
Interaction	LCK interactions	ANKRD26 CDC42BPB HSP90AA1 HSP90AB1 HSP90AB3P	3.08e-05	463	17	5	int:LCK
Interaction	NUMA1 interactions	ASPM SMC3 TLN1 HSP90AA1 HSP90AB1	3.28e-05	469	17	5	int:NUMA1
Interaction	ANKRD55 interactions	SMC3 TLN1 HSP90AA1 HSP90AB1	3.38e-05	228	17	4	int:ANKRD55
Interaction	HLA-DRB4 interactions	HSP90AA1 HSP90AB1	4.40e-05	12	17	2	int:HLA-DRB4
Interaction	UNC13C interactions	HSP90AA1 HSP90AB1	4.40e-05	12	17	2	int:UNC13C
Interaction	MYG1 interactions	SKIL HSP90AA1 HSP90AB1	4.55e-05	84	17	3	int:MYG1
Interaction	FKBP6 interactions	HSP90AA5P HSP90AA1 HSP90AB1	4.89e-05	86	17	3	int:FKBP6
Interaction	BMX interactions	HSP90AA1 HSP90AB1 HSP90AB3P	5.60e-05	90	17	3	int:BMX
Interaction	FGR interactions	HSP90AA1 HSP90AB1 HSP90AB3P	6.17e-05	93	17	3	int:FGR
Interaction	HSP90AA5P interactions	HSP90AA5P HSP90AA1 HSP90AB1	6.17e-05	93	17	3	int:HSP90AA5P
Interaction	TRAF3IP1 interactions	SMC3 HSP90AA1 HSP90AB1	6.79e-05	96	17	3	int:TRAF3IP1
Interaction	LY6E interactions	HSP90AA1 HSP90AB1	6.99e-05	15	17	2	int:LY6E
Interaction	TESK2 interactions	HSP90AA5P HSP90AA1 HSP90AB1	7.00e-05	97	17	3	int:TESK2
Interaction	HSP90AB3P interactions	HSP90AA1 HSP90AB1 HSP90AB3P	7.22e-05	98	17	3	int:HSP90AB3P
Interaction	MYLK2 interactions	HSP90AA1 HSP90AB1 HSP90AB3P	7.89e-05	101	17	3	int:MYLK2
Interaction	FKBP4 interactions	HSP90AA5P MAP4K1 HSP90AA1 HSP90AB1	8.06e-05	285	17	4	int:FKBP4
Interaction	LRRK1 interactions	MAP4K1 HSP90AA1 HSP90AB1	8.13e-05	102	17	3	int:LRRK1
Interaction	PTK6 interactions	HSP90AA1 HSP90AB1 HSP90AB3P	8.61e-05	104	17	3	int:PTK6
Interaction	SCG2 interactions	HSP90AA1 HSP90AB1	9.04e-05	17	17	2	int:SCG2
Interaction	IKBKE interactions	MAP4K1 HSP90AA1 HSP90AB1	9.12e-05	106	17	3	int:IKBKE
Interaction	FBXL4 interactions	HSP90AA1 HSP90AB1 HSP90AB3P	9.12e-05	106	17	3	int:FBXL4
Interaction	CEBPB interactions	ASPM SKIL SMC3 TLN1 HSP90AA1 GIPC2 HSP90AB1	9.75e-05	1443	17	7	int:CEBPB
Interaction	NANS interactions	SKIL HSP90AA1 HSP90AB1	9.90e-05	109	17	3	int:NANS
Interaction	STK32A interactions	HSP90AA1 HSP90AB1	1.02e-04	18	17	2	int:STK32A
Interaction	CDK3 interactions	HSP90AA5P HSP90AA1 HSP90AB1	1.13e-04	114	17	3	int:CDK3
Interaction	SLC34A1 interactions	HSP90AA1 HSP90AB1	1.14e-04	19	17	2	int:SLC34A1
Interaction	TNNI3K interactions	HSP90AA1 HSP90AB1	1.14e-04	19	17	2	int:TNNI3K
Interaction	AGO4 interactions	HSP90AA5P HSP90AA1 HSP90AB1	1.25e-04	118	17	3	int:AGO4
Interaction	MAP2K5 interactions	CDC42BPB HSP90AA1 HSP90AB1	1.32e-04	120	17	3	int:MAP2K5
Interaction	STK11 interactions	HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	1.35e-04	326	17	4	int:STK11
Interaction	IP6K2 interactions	HSP90AA1 HSP90AB1	1.39e-04	21	17	2	int:IP6K2
Interaction	SYNDIG1 interactions	HSP90AA1 HSP90AB1	1.39e-04	21	17	2	int:SYNDIG1
Interaction	CDC37 interactions	HSP90AA5P MAP4K1 HSP90AA1 HSP90AB1 HSP90AB3P	1.49e-04	645	17	5	int:CDC37
Interaction	FAF1 interactions	SKIL TLN1 HSP90AA1 HSP90AB1	1.49e-04	334	17	4	int:FAF1
Interaction	DTX4 interactions	MAP4K1 HSP90AA1	1.53e-04	22	17	2	int:DTX4
Interaction	ZNF215 interactions	HSP90AA1 HSP90AB1	1.53e-04	22	17	2	int:ZNF215
Interaction	NUDC interactions	MAP4K1 TLN1 HSP90AA1 HSP90AB1	1.54e-04	337	17	4	int:NUDC
Interaction	HSP90B1 interactions	ASPM SMC3 CDC42BPB HSP90AA1 HSP90AB1	1.54e-04	650	17	5	int:HSP90B1
Interaction	CHORDC1 interactions	HSP90AA1 HSP90AB1 HSP90AB3P	1.67e-04	130	17	3	int:CHORDC1
Interaction	MAP4K1 interactions	MAP4K1 HSP90AA1 HSP90AB1	1.67e-04	130	17	3	int:MAP4K1
Interaction	MAP3K15 interactions	TNFSF13B HSP90AA1	1.68e-04	23	17	2	int:MAP3K15
Interaction	GSDMD interactions	HSP90AA1 HSP90AB1	1.68e-04	23	17	2	int:GSDMD
Interaction	CDK18 interactions	HSP90AA5P HSP90AA1 HSP90AB1	1.71e-04	131	17	3	int:CDK18
Interaction	FTL interactions	ASPM SMC3 SLF1 HSP90AB3P	1.74e-04	348	17	4	int:FTL
Interaction	MTOR interactions	ASPM TNFSF13B HSP90AA1 HSP90AB1	1.76e-04	349	17	4	int:MTOR
Interaction	PCBP1 interactions	SMC3 HSP90AA5P TLN1 HSP90AA1 HSP90AB1	1.79e-04	671	17	5	int:PCBP1
Interaction	SPHKAP interactions	HSP90AA1 HSP90AB1	1.83e-04	24	17	2	int:SPHKAP
Interaction	TTC9C interactions	CDC42BPB HSP90AA1 HSP90AB1	1.91e-04	136	17	3	int:TTC9C
Interaction	LURAP1 interactions	ASPM ANKRD26 CDC42BPB	1.95e-04	137	17	3	int:LURAP1
Interaction	CDK9 interactions	SMC3 HSP90AA5P HSP90AA1 HSP90AB1 HSP90AB3P	1.97e-04	685	17	5	int:CDK9
Interaction	NEK11 interactions	HSP90AA1 HSP90AB1	1.99e-04	25	17	2	int:NEK11
Interaction	ITGB1BP2 interactions	HSP90AA1 HSP90AB1	1.99e-04	25	17	2	int:ITGB1BP2
Interaction	CDKL1 interactions	HSP90AA5P HSP90AB3P	1.99e-04	25	17	2	int:CDKL1
Interaction	MOB3C interactions	SMC3 TLN1 HSP90AA1 HSP90AB1	2.07e-04	364	17	4	int:MOB3C
Interaction	YWHAQ interactions	ANKRD26 ANKRD18A TNFSF13B TLN1 HSP90AA1 HSP90AB1	2.10e-04	1118	17	6	int:YWHAQ
Interaction	DDX59 interactions	HSP90AA1 HSP90AB1	2.15e-04	26	17	2	int:DDX59
Interaction	METTL22 interactions	HSP90AA1 HSP90AB1	2.15e-04	26	17	2	int:METTL22
Interaction	TSSK2 interactions	HSP90AA1 HSP90AB1	2.15e-04	26	17	2	int:TSSK2
Cytoband	Ensembl 112 genes in cytogenetic band chr9p13	ANKRD18A TLN1	1.87e-03	174	17	2	chr9p13
Cytoband	Ensembl 112 genes in cytogenetic band chr6p21	APOBEC2 HSP90AB1	1.46e-02	503	17	2	chr6p21
Cytoband	Ensembl 112 genes in cytogenetic band chr14q32	CDC42BPB HSP90AA1	1.83e-02	566	17	2	chr14q32
GeneFamily	Heat shock 90kDa proteins	HSP90AA1 HSP90AB1	4.77e-06	5	13	2	586
GeneFamily	Ankyrin repeat domain containing	ANKRD26 ANKRD18A SLF1	6.13e-04	242	13	3	403
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	ASPM SMC3 HSP90AA1 SLF1 ITPR2	3.36e-05	656	16	5	M18979
Coexpression	KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP	ASPM SMC3 TNFSF13B HSP90AA1 SLF1 HSP90AB1	7.34e-05	1290	16	6	M80
Coexpression	WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP	ANKRD26 MAP4K1 ANKRD18A TNFSF13B	7.78e-05	392	16	4	M2131
Coexpression	SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP	ASPM SMC3 HSP90AA1 HSP90AB1	8.74e-05	404	16	4	M19488
Coexpression	GSE7219_WT_VS_NIK_NFKB2_KO_DC_UP	SKIL HSP90AA1 HSP90AB1	1.81e-04	185	16	3	M377
Coexpression	GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_DN	SKIL TNFSF13B HSP90AB1	1.96e-04	190	16	3	M384
Coexpression	GSE369_SOCS3_KO_VS_IFNG_KO_LIVER_UP	SKIL SLF1 ITPR2	2.24e-04	199	16	3	M5978
Coexpression	GSE34006_UNTREATED_VS_A2AR_AGONIST_TREATED_TREG_DN	MAP4K1 TLN1 HSP90AB1	2.28e-04	200	16	3	M9050
Coexpression	GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_IL4_DN	ANKRD26 HSP90AA1 SLF1	2.28e-04	200	16	3	M5081
Coexpression	GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_DN	ANKRD26 MAP4K1 ITPR2	2.28e-04	200	16	3	M3202
Coexpression	GSE27670_CTRL_VS_BLIMP1_TRANSDUCED_GC_BCELL_DN	HSP90AA1 GIPC2 HSP90AB1	2.28e-04	200	16	3	M8208
Coexpression	TABULA_MURIS_SENIS_LUNG_FIBROBLAST_OF_LUNG_AGEING	TLN1 HSP90AA1 HSP90AB1	3.18e-04	224	16	3	MM3767
Coexpression	SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP	HSP90AA1 HSP90AB1	3.41e-04	45	16	2	M104
Coexpression	TABULA_MURIS_SENIS_LUNG_ADVENTITIAL_CELL_AGEING	TNFSF13B HSP90AA1 HSP90AB1	3.61e-04	234	16	3	MM3761
CoexpressionAtlas	facebase_RNAseq_e10.5_MandArch_2500	ASPM ANKRD26 SMC3 MAP4K1 HSP90AA1 GIPC2 SLF1 ITPR2	3.99e-06	1468	16	8	facebase_RNAseq_e10.5_MandArch_2500
CoexpressionAtlas	facebase_RNAseq_e10.5_MandArch_2500_K1	ASPM ANKRD26 SMC3 MAP4K1 HSP90AA1 SLF1 ITPR2	1.64e-05	1241	16	7	facebase_RNAseq_e10.5_MandArch_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500	ASPM ANKRD26 SMC3 HSP90AA1 HSP90AB3P	2.45e-05	498	16	5	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	ASPM ANKRD26 SMC3 HSP90AA1 HSP90AB1 HSP90AB3P	5.38e-05	989	16	6	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	ASPM ANKRD26 SMC3 HSP90AA1 SLF1 HSP90AB1	2.03e-04	1257	16	6	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	HSP90AA1 HSP90AB1 HSP90AB3P	2.57e-04	169	16	3	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3	ASPM ANKRD26 SMC3	3.74e-04	192	16	3	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500	ASPM ANKRD26 SMC3 TNFSF13B HSP90AA1 SLF1	3.86e-04	1414	16	6	facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	ASPM ANKRD26 SMC3 HSP90AA1 SLF1 HSP90AB1	4.58e-04	1459	16	6	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000	ASPM ANKRD26 SMC3 HSP90AB1 HSP90AB3P	5.99e-04	983	16	5	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000	SMC3 CDC42BPB HSP90AA1 HSP90AB1 HSP90AB3P	6.22e-04	991	16	5	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000
ToppCell	PND03\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SKIL TLN1 HSP90AA1 GIPC2	6.59e-07	187	17	4	b3fcb36d853adfdea7172c5591de06f027e50af3
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	ASPM ANKRD26 ANKRD18A HSP90AA1	8.12e-07	197	17	4	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	ANKRD26 SMC3 ANKRD18A HSP90AA1	8.45e-07	199	17	4	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	ANKRD26 SMC3 ANKRD18A HSP90AA1	8.45e-07	199	17	4	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular\|TCGA-Stomach / Sample_Type by Project: Shred V9	ASPM HSP90AB1 HSP90AB3P	1.86e-05	138	17	3	93497c0a5d5e54006653b2dedc7a7041e1a613e6
ToppCell	Dividing_Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	ASPM TNFSF13B SLF1	3.23e-05	166	17	3	c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TNFSF13B HSP90AA1 HSP90AB1	3.41e-05	169	17	3	d4a0bd792bddfa34332d7dc432ce253f50d98c6f
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SKIL HSP90AA1 HSP90AB1	3.91e-05	177	17	3	ea2c2d2d7ffd34780882299229ff8614fdd7c79c
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SKIL HSP90AA1 HSP90AB1	3.91e-05	177	17	3	63b5ebbe505f22091bc7b0db818e01fae5d92bb7
ToppCell	Severe-CD4+_T_activated\|Severe / Disease group and Cell class	TNFSF13B HSP90AA1 HSP90AB1	3.91e-05	177	17	3	a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMC3 HSP90AA1 HSP90AB1	3.97e-05	178	17	3	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	Severe-CD4+_T_activated\|World / Disease group and Cell class	TNFSF13B HSP90AA1 HSP90AB1	3.97e-05	178	17	3	ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HSP90AA5P TNFSF13B HSP90AB3P	4.25e-05	182	17	3	b86690c109cdc16844a6cd2216c1bf2bf28efd45
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SKIL HSP90AA1 HSP90AB1	4.32e-05	183	17	3	7534587fa35837c0aaca93c542f2eee493eba637
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HSP90AA5P TNFSF13B HSP90AB3P	4.53e-05	186	17	3	855c2e5a8a6cf94c7de31982e0e2416f924439d3
ToppCell	COVID-19_Mild-Neu_4\|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients	ASPM SMC3 HSP90AB1	4.60e-05	187	17	3	714851e757c71c559ee6413a3f61d6c117c79ad2
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-Trm_Th1/Th17\|lymph-node_spleen / Manually curated celltypes from each tissue	HSP90AA1 SLF1 HSP90AB1	4.68e-05	188	17	3	a20521198c6db17589535fb439533329582c9dd2
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-Trm_Th1/Th17\|Lung / Manually curated celltypes from each tissue	HSP90AA1 SLF1 HSP90AB1	4.75e-05	189	17	3	f43960506ed3e699e910ec7711c1113e2e9b80d1
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SKIL HSP90AA1 HSP90AB1	4.83e-05	190	17	3	4d401b73c0e7eb38e95d0851a128bf12bb0d3a9f
ToppCell	Myeloid-Myeloid-B_(Activated_Macrophage)\|Myeloid / shred on cell class and cell subclass (v4)	HSP90AA1 ITPR2 HSP90AB1	4.90e-05	191	17	3	7bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCell	10x3'2.3\|World / cell types per 3 fetal stages;per 3',per 5'	SKIL HSP90AA1 HSP90AB1	5.13e-05	194	17	3	fc7ed8350ffe1475b8934dfbb107b51991876b0b
ToppCell	HSPCs-Mk_prog.\|World / Lineage and Cell class	SKIL MAP4K1 TLN1	5.13e-05	194	17	3	5049f4f102844d766eca577e809cf21f7908a9d2
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SKIL HSP90AA1 HSP90AB1	5.21e-05	195	17	3	562e4c0e4e81f6303e57b846da71d1667fc35963
ToppCell	(0)_NK_cells-(0)_NK_CD160pos\|(0)_NK_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	TLN1 HSP90AA1 HSP90AB1	5.21e-05	195	17	3	6cbeceb52bb207f3c074e57b5b3f7cfb24fd5877
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SKIL HSP90AA1 HSP90AB1	5.21e-05	195	17	3	fa8ac154e5aebc26463ff84f0ad1038095770bc6
ToppCell	COVID-19_Severe\|World / Disease condition and Cell class	TLN1 HSP90AA1 HSP90AB1	5.29e-05	196	17	3	450ac2aff89c5ca73b8bfbc80663e03be066931f
ToppCell	E12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ASPM SMC3 HSP90AA1	5.29e-05	196	17	3	62b2de1d38a99ab23211bf51595845f8a1fdb7d2
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-immature_B_cell\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SKIL HSP90AA1 HSP90AB1	5.29e-05	196	17	3	9a6e4eea19348a6e3379d3b872456ab6280cb74f
ToppCell	10x3'2.3-week_17-19\|World / cell types per 3 fetal stages;per 3',per 5'	SKIL HSP90AA1 HSP90AB1	5.37e-05	197	17	3	f5cfad0b42d0f817e22cc78b9bfb2b4b7e4330ed
ToppCell	COVID-19-kidney-Macrophages\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TNFSF13B HSP90AA1 ITPR2	5.37e-05	197	17	3	3912301018d0863144dcfac8d1fa8adc081748d7
ToppCell	myeloid-Dendritic_cell-Conventional_dendritic_cell\|myeloid / Lineage, cell class and subclass	MAP4K1 HSP90AA1 HSP90AB1	5.54e-05	199	17	3	1e7ce1a1d6a7af18351d64b7a5334efa6dd9abc5
ToppCell	Bronchial_Biopsy-Immune-Dendritic_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	SKIL TNFSF13B TLN1	5.54e-05	199	17	3	be916332291ea48e244c05ab1855f9fcd718ac54
ToppCell	Transverse-T_cell-Th1\|T_cell / Region, Cell class and subclass	HSP90AA1 SLF1 HSP90AB1	5.54e-05	199	17	3	9271d9d36ffe1c169049d4340258f366916adfaf
ToppCell	Severe\|World / Disease group and Cell class	ASPM HSP90AA1 HSP90AB1	5.54e-05	199	17	3	b73ae402b258fcc17e6cd6d6045244eccfe38ef8
ToppCell	(00)_Basal-(2)_GFP_FOXI1\|(00)_Basal / shred by cell type by condition	ANKRD26 SMC3 HSP90AA1	5.54e-05	199	17	3	19674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-CD4_TRM/EMRA\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ASPM MAP4K1 HSP90AA1	5.54e-05	199	17	3	5a29db2610ba06a2248325a16cad755d20debf2c
ToppCell	myeloid-Dendritic_cell\|myeloid / Lineage, cell class and subclass	MAP4K1 HSP90AA1 HSP90AB1	5.54e-05	199	17	3	b81c0a40481f1006ac4aa8759af95448cb5fc2e6
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ASPM SMC3 SLF1	5.54e-05	199	17	3	c7c501ad144ac5488d0b0496554d46616f2e01a6
ToppCell	severe\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TLN1 HSP90AA1 HSP90AB1	5.62e-05	200	17	3	accc618d6b960bff30cb531c1226295bfc8650f6
ToppCell	severe-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TLN1 HSP90AA1 HSP90AB1	5.62e-05	200	17	3	6aa77955017d073a96324e4db6b9950a2ec46cf8
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	TLN1 HSP90AA1 HSP90AB1	5.62e-05	200	17	3	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	myeloid-pro-cDC\|myeloid / Lineage and Cell class	ASPM SMC3 MAP4K1	5.62e-05	200	17	3	4aa2308eeb94e0bdff4e02eb9e45ba8837ae14bf
ToppCell	severe-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TLN1 HSP90AA1 HSP90AB1	5.62e-05	200	17	3	2253d74049cc49c92e897ff4aa298d913daeb739
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Tac1-Inhibitory_Gad1Gad2_Id2.Tac1_(Interneuron,_Neurogliaform1)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	TNFSF13B GIPC2	2.04e-04	56	17	2	c1bdee477c871c03d60feed26b24d9f3d4171cb6
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Tac1-Inhibitory_Gad1Gad2_Id2.Tac1_(Interneuron,_Neurogliaform1)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	TNFSF13B GIPC2	2.04e-04	56	17	2	c78cbec68922b382595758e100dda9d284836c25
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	SKIL TNFSF13B	5.05e-04	88	17	2	142d2e00ef19c0ad011a21945bf1111271056eae
ToppCell	Frontal_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)--\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TNFSF13B APOBEC2	5.63e-04	93	17	2	d84d8fb3f2553364edf4cf5488a2747512fe65af
ToppCell	Frontal_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TNFSF13B APOBEC2	5.63e-04	93	17	2	3223e3e4e1a571bd947949ae545c49cfefe53dce
ToppCell	Frontal_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TNFSF13B APOBEC2	5.63e-04	93	17	2	b6653a0eafe0409d7582640706e729202f3b40ea
ToppCell	Frontal_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TNFSF13B APOBEC2	5.63e-04	93	17	2	78de1ca2c5a8511580fa47734df951d0ee5c518a
ToppCell	TCGA-Ovary-Primary_Tumor\|TCGA-Ovary / Sample_Type by Project: Shred V9	CDC42BPB TLN1	7.31e-04	106	17	2	14f548be39cec604fbdae0382cbf434fa4049840
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma\|TCGA-Ovary / Sample_Type by Project: Shred V9	CDC42BPB TLN1	7.31e-04	106	17	2	939b80950d39cdc7149a05fdfb64c8810064cdb1
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma\|TCGA-Ovary / Sample_Type by Project: Shred V9	CDC42BPB TLN1	7.31e-04	106	17	2	e9e1b55f32b3d5b9eeec94a997912e5c21c1fb48
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-mDC\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAP4K1 TNFSF13B	1.13e-03	132	17	2	f8e2ba53063007d7507f1837ad669b0e4333cd23
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic-granulocyte\|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ANKRD18A HSP90AB1	1.23e-03	138	17	2	d29eb8d361609048e789334a78c51064c296ad2a
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	HSP90AA1 HSP90AB1	1.30e-03	142	17	2	d60d2a5d0876a552bc161fc4e2dfe180f88f03a5
ToppCell	tumor_Lung-T/NK_cells-CD8_low_T\|T/NK_cells / Location, Cell class and cell subclass	HSP90AA1 SLF1	1.30e-03	142	17	2	eaf08a0dbacc9ebbd54e377922e76d8ba854dcb8
ToppCell	NS-control-d_0-4-Epithelial-Ciliated-diff\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	HSP90AA1 HSP90AB1	1.30e-03	142	17	2	1e57c75e9f28aae2ca99543448433fa7326398ad
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_3\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	APOBEC2 HSP90AB1	1.34e-03	144	17	2	ce5e219f2548b51440b8b3e1a9f011afd4510d19
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated\|lymph-node_spleen / Manually curated celltypes from each tissue	HSP90AA1 HSP90AB1	1.43e-03	149	17	2	32b0a8789d3be4889821afab0b52214deeff7e4d
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|367C / Donor, Lineage, Cell class and subclass (all cells)	SMC3 ITPR2	1.43e-03	149	17	2	41f28138bde45d0b814e116837e5a32b5e80d54a
ToppCell	Dividing_Macrophages-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	ASPM TNFSF13B	1.49e-03	152	17	2	e39cfc346b35235546b303e7d73e4d9d7120a5fb
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP4K1 APOBEC2	1.53e-03	154	17	2	3fa6f77ad2c30ec24b9b904e2732ec5b419dff5b
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP4K1 APOBEC2	1.53e-03	154	17	2	ee03b386d28a524084eaf1c0091f7389daa34250
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-Tfh\|Liver / Manually curated celltypes from each tissue	ANKRD26 ANKRD18A	1.57e-03	156	17	2	85bc34ff507f9a66c6e3ba7a3ffd5416d0073ccf
ToppCell	human_hepatoblastoma-Tumor_cells-T4\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	HSP90AA1 HSP90AB1	1.61e-03	158	17	2	53afcc8132cd61bae1adbdedb83e5bac6690bc8d
ToppCell	356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1\|356C / Donor, Lineage, Cell class and subclass (all cells)	MAP4K1 SLF1	1.61e-03	158	17	2	cf1b77abd05f18526679c0d305b4dd2caef2b306
ToppCell	3'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSP90AA1 ITPR2	1.63e-03	159	17	2	6ec5489d55667e53bd9c021ada7de458bfef43a3
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ASPM ANKRD18A	1.63e-03	159	17	2	2233fee5dcdb6c7dee5b1bd8efbc07d86b339927
ToppCell	343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	HSP90AA1 HSP90AB1	1.65e-03	160	17	2	21f7c0337fbd99e4a20650920d8302d7318bd25e
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ASPM MAP4K1	1.67e-03	161	17	2	0dd1401b4c990d49fccb702a9f9867590a58e203
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ASPM MAP4K1	1.67e-03	161	17	2	b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ASPM MAP4K1	1.67e-03	161	17	2	efb811dda4d73107983a5f68302bdcf4f408d5b4
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ASPM MAP4K1	1.67e-03	161	17	2	28d5dbd20c9f8e0069f172d552997a044790e1a7
ToppCell	control-Epithelial-Ciliated-diff\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	HSP90AA1 HSP90AB1	1.67e-03	161	17	2	ef4b946914a4e2727ed57362dc6965c299520f35
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_3\|343B / Donor, Lineage, Cell class and subclass (all cells)	SKIL TNFSF13B	1.69e-03	162	17	2	0acb8f7b51bf422d4f4f8e99bd10360163ae4eb7
ToppCell	3'-Adult-Distal_Rectal-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSP90AA1 ITPR2	1.69e-03	162	17	2	075f73ff10e1a7f5695e014e47acc4db513e9cfb
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MAP4K1 HSP90AB1	1.69e-03	162	17	2	3b89c3758835b7b9f9d4fb0bc8ed06da382fe48b
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-Trm_Th1/Th17\|bone_marrow / Manually curated celltypes from each tissue	HSP90AA1 HSP90AB1	1.71e-03	163	17	2	4d1fd0b1246833723b938eca0cb246e937380e12
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ASPM MAP4K1	1.73e-03	164	17	2	249d8f75a64bce7db52ce0c563f496b9edf602a6
ToppCell	PSB-critical-LOC-Lymphoid-PC\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ASPM MAP4K1	1.73e-03	164	17	2	3e672124dea2497c5bdf8a315c8cfacfab5780dc
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ASPM MAP4K1	1.75e-03	165	17	2	953c8242a81a39ade63ac8e5b34fe58575771746
ToppCell	Monocytes-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	TNFSF13B TLN1	1.75e-03	165	17	2	83d06210a50073fbb7082eabd8298dd355c40416
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP4K1 APOBEC2	1.77e-03	166	17	2	6842735750dcb361e4c9844f05233b0fbb879652
ToppCell	facs-Heart-RV-24m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP4K1 APOBEC2	1.77e-03	166	17	2	16d42eda958b2a6f9d598e9b4b967505dee426ef
ToppCell	facs-Heart-RV-24m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP4K1 APOBEC2	1.77e-03	166	17	2	08d7db4ff1c9c9cea3a36a87b8690838e79d4e0e
ToppCell	facs-Brain_Myeloid-Cerebellum_-18m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SKIL TNFSF13B	1.77e-03	166	17	2	4ab1959c526c2fd83077fc03e4de207f34841a19
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated\|Liver / Manually curated celltypes from each tissue	ANKRD26 CDC42BPB	1.77e-03	166	17	2	9afa33b5ad27dc33576be592f9b22d8161366838
ToppCell	Dividing_Macrophages-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	ASPM TNFSF13B	1.77e-03	166	17	2	ea95b94ccc2ac67df741b30c27f4ae698925875f
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells-CD8_Tmem\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP4K1 HSP90AA1	1.80e-03	167	17	2	d80b64322d16d98c82a52724809740b9de208f39
ToppCell	facs-Heart-LV-24m-Lymphocytic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP4K1 APOBEC2	1.80e-03	167	17	2	4a669eafde3582a451614ad304769b47aa1d9578
ToppCell	facs-Kidney-nan-24m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP4K1 APOBEC2	1.80e-03	167	17	2	3c4183a8225bae37b9f5341ebd1b95409ced2022
ToppCell	facs-Kidney-nan-24m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP4K1 APOBEC2	1.80e-03	167	17	2	28e9670586ff551b700c794313d27eedbfa1286b
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAP4K1 APOBEC2	1.80e-03	167	17	2	3c3e1c31aacca48099693aea2efdfa22fc0e4af4
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	APOBEC2 ITPR2	1.80e-03	167	17	2	b0eb7a40491dd2432f5282f578ce569df86d21a7
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-Zbtb32+_B_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAP4K1 APOBEC2	1.80e-03	167	17	2	77a4d7ce44847c76074d4f5340d61b398fe43e6c
ToppCell	facs-Spleen-nan-24m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APOBEC2 HSP90AA1	1.80e-03	167	17	2	9a8e291c082d7c26bab21df77bd36ce927032a70
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSP90AA1 HSP90AB1	1.82e-03	168	17	2	696b31bedbc7d40817a733e8c6ec2633404be619
ToppCell	LPS-antiTNF-Myeloid-Dendritic_cells-mDC\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAP4K1 TNFSF13B	1.82e-03	168	17	2	2dca1c4a33b6da9357fa3b2a523af19baab1c21c
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l4\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	APOBEC2 ITPR2	1.82e-03	168	17	2	19d2c763b50e7168dfa7449fc407489b055526c2
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HSP90AA1 HSP90AB1	1.14e-03	50	11	2	GAVISH_3CA_METAPROGRAM_CD4_T_CELLS_STRESS_HSP
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HSP90AA1 HSP90AB1	1.14e-03	50	11	2	GAVISH_3CA_METAPROGRAM_B_CELLS_HSP_STRESS
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HSP90AA1 HSP90AB1	1.14e-03	50	11	2	GAVISH_3CA_METAPROGRAM_MACROPHAGES_STRESS_HSP
Computational	Genes upregulated in subsets of cells of a given type within various tumors	HSP90AA1 HSP90AB1	1.14e-03	50	11	2	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_HEAT_SHOCK
Drug	8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE	HSP90AA1 HSP90AB1	4.63e-07	2	16	2	DB07877
Drug	4-[4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-METHYL-1H-PYRAZOL-5-YL]-6-ETHYLBENZENE-1,3-DIOL	HSP90AA1 HSP90AB1	4.63e-07	2	16	2	DB07594
Drug	9-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-Amine	HSP90AA1 HSP90AB1	4.63e-07	2	16	2	DB02754
Drug	Geldanamycin	HSP90AA1 HSP90AB1	4.63e-07	2	16	2	DB02424
Drug	N-(5-methylisoxazol-3-yl)-2-(4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-ylthio)acetamide	HSP90AA1 HSP90AB1	2.78e-06	4	16	2	ctd:C576667
Drug	Riboflavine [83-88-5]; Down 200; 10.6uM; MCF7; HT_HG-U133A	SKIL ANKRD26 TLN1 ITPR2	9.49e-06	199	16	4	2760_DN
Drug	NSC330499	HSP90AA1 HSP90AB1	9.70e-06	7	16	2	CID000433447
Drug	phenyldichloroarsine	HSP90AA1 HSP90AB1	1.29e-05	8	16	2	CID000012762
Drug	6-anilino-5,8-quinolinedione	HSP90AA1 HSP90AB1	1.66e-05	9	16	2	ctd:C041715
Drug	5,8-quinolinedione	HSP90AA1 HSP90AB1	1.66e-05	9	16	2	CID000388306
Drug	Pu-3	HSP90AA1 HSP90AB1	2.54e-05	11	16	2	CID000448965
Drug	AC1L9PMA	HSP90AA1 HSP90AB1	4.84e-05	15	16	2	CID000451405
Drug	BHTOH-QM	HSP90AA1 HSP90AB1	7.86e-05	19	16	2	ctd:C110172
Drug	dimyristoylphosphatidic acid	ASPM SMC3	8.73e-05	20	16	2	CID000093134
Drug	dimethyl pimelimidate	HSP90AA1 HSP90AB1	8.73e-05	20	16	2	CID000065403
Drug	tamoxifen aziridine	HSP90AA1 HSP90AB1	1.06e-04	22	16	2	CID003033894
Drug	CCT018159	HSP90AA1 HSP90AB1	1.06e-04	22	16	2	CID005327091
Drug	S2A	HSP90AA1 HSP90AB1	1.16e-04	23	16	2	CID016058643
Drug	SC-10	HSP90AA1 HSP90AB1	1.73e-04	28	16	2	CID000005175
Drug	2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone	HSP90AA1 HSP90AB1	1.73e-04	28	16	2	ctd:C024709
Drug	TM02	HSP90AA1 HSP90AB1	1.73e-04	28	16	2	CID000012902
Drug	p-iodophenol	HSP90AA1 HSP90AB1	1.86e-04	29	16	2	CID000010894
Drug	17-AAG; Up 200; 1uM; HL60; HT_HG-U133A	HSP90AA1 ITPR2 HSP90AB1	2.21e-04	172	16	3	1159_UP
Drug	1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid	HSP90AA1 HSP90AB1	2.27e-04	32	16	2	ctd:C025603
Drug	prostaglandin A1	HSP90AA1 HSP90AB1	2.56e-04	34	16	2	ctd:C100573
Drug	Adenosine-5'-Diphosphate	HSP90AA1 HSP90AB1	2.88e-04	36	16	2	DB03431
Drug	Humic Substances	HSP90AA1 HSP90AB1	2.88e-04	36	16	2	ctd:D006812
Drug	Thioguanosine [85-31-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A	ASPM ANKRD26 SMC3	2.96e-04	190	16	3	2619_DN
Drug	2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A_EA	ANKRD26 TLN1 ITPR2	3.14e-04	194	16	3	1060_UP
Drug	Benperidol [2062-84-2]; Down 200; 10.4uM; HL60; HT_HG-U133A	SKIL ANKRD26 ITPR2	3.19e-04	195	16	3	2475_DN
Drug	Zuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; HL60; HT_HG-U133A	SKIL ANKRD26 ITPR2	3.24e-04	196	16	3	2936_DN
Drug	Midecamycin [35457-80-8]; Down 200; 5uM; PC3; HT_HG-U133A	ANKRD26 TLN1 ITPR2	3.24e-04	196	16	3	6745_DN
Drug	Reserpinic acid hydrochloride; Down 200; 9.2uM; HL60; HT_HG-U133A	ANKRD26 APOBEC2 ITPR2	3.29e-04	197	16	3	2903_DN
Drug	SC-58125; Down 200; 10uM; MCF7; HG-U133A	SKIL APOBEC2 TLN1	3.29e-04	197	16	3	208_DN
Drug	Tiabendazole [148-79-8]; Down 200; 19.8uM; HL60; HT_HG-U133A	SKIL ANKRD26 ITPR2	3.29e-04	197	16	3	2479_DN
Drug	Sisomicin sulfate [53179-09-2]; Down 200; 2.8uM; MCF7; HT_HG-U133A	ANKRD26 TLN1 ITPR2	3.29e-04	197	16	3	2853_DN
Drug	Estropipate [7280-37-7]; Up 200; 9.2uM; PC3; HT_HG-U133A	ANKRD26 APOBEC2 ITPR2	3.34e-04	198	16	3	4472_UP
Drug	Suxibuzone [27470-51-5]; Up 200; 9.2uM; PC3; HT_HG-U133A	SKIL ANKRD26 ITPR2	3.39e-04	199	16	3	5806_UP
Drug	AC1L1JAF	HSP90AA1 HSP90AB1	4.50e-04	45	16	2	CID000004952
Drug	Albendazole	HSP90AA1 HSP90AB1	4.71e-04	46	16	2	ctd:D015766
Drug	AC1L194G	HSP90AA1 HSP90AB1	5.34e-04	49	16	2	CID000000386
Drug	tanespimycin	HSP90AA1 HSP90AB1	6.97e-04	56	16	2	ctd:C112765
Drug	nickel hydroxide	SKIL MAP4K1 TNFSF13B	7.30e-04	259	16	3	CID000025500
Drug	pyrithione zinc	HSP90AA1 HSP90AB1	9.97e-04	67	16	2	ctd:C010423
Drug	2-amino-4,6-dinitrotoluene	HSP90AA1 HSP90AB1	1.09e-03	70	16	2	ctd:C035208
Drug	alachlor	SMC3 HSP90AA1	1.12e-03	71	16	2	CID000002078
Drug	dimethyl phthalate	ASPM SKIL TLN1 ITPR2	1.29e-03	714	16	4	ctd:C024629
Drug	Succimer	SKIL ANKRD26 TNFSF13B SLF1 ITPR2	1.37e-03	1264	16	5	ctd:D004113
Disease	intrahepatic cholangiocarcinoma (is_marker_for)	HSP90AA1 HSP90AB1	4.69e-05	19	16	2	DOID:4928 (is_marker_for)
Disease	muscular atrophy (biomarker_via_orthology)	HSP90AB1 HSP90AB3P	1.11e-04	29	16	2	DOID:767 (biomarker_via_orthology)
Disease	pancreatitis (biomarker_via_orthology)	HSP90AB1 HSP90AB3P	2.02e-04	39	16	2	DOID:4989 (biomarker_via_orthology)
Disease	pulmonary fibrosis (biomarker_via_orthology)	HSP90AB1 HSP90AB3P	3.33e-04	50	16	2	DOID:3770 (biomarker_via_orthology)
Disease	cancer (implicated_via_orthology)	HSP90AA1 HSP90AB1 HSP90AB3P	3.80e-04	268	16	3	DOID:162 (implicated_via_orthology)
Disease	Neurodevelopmental Disorders	SMC3 CDC42BPB	1.15e-03	93	16	2	C1535926
Disease	HIV Coinfection	HSP90AA1 HSP90AB1	1.40e-03	103	16	2	C4505456
Disease	HIV Infections	HSP90AA1 HSP90AB1	1.40e-03	103	16	2	C0019693
Disease	QT interval	TNFSF13B GIPC2 ITPR2	2.77e-03	534	16	3	EFO_0004682
Disease	Mood Disorders	TNFSF13B HSP90AA1	3.67e-03	168	16	2	C0525045
Disease	obesity (implicated_via_orthology)	ANKRD26 ITPR2	5.93e-03	215	16	2	DOID:9970 (implicated_via_orthology)
Disease	platelet component distribution width	TNFSF13B TLN1 GIPC2	7.29e-03	755	16	3	EFO_0007984
Disease	platelet crit	TNFSF13B TLN1 ITPR2	1.37e-02	952	16	3	EFO_0007985
Disease	serum non-albumin protein measurement	CDC42BPB TNFSF13B	1.60e-02	361	16	2	EFO_0004568

Protein segments in the cluster

Peptide	Gene	Start	Entry
EKCEKLEKDKKMLEE	ANKRD18A	786	Q8IVF6
KLKELKKEELFTMKL	GIPC2	181	Q8TF65
CELLTVKIKKMEDKV	ANKRD26	746	Q9UPS8
AQRKLLMLKKEKLEK	ASPM	1331	Q8IZT6
LKKLKEAGCKLRIMK	APOBEC2	166	Q9Y235
KKLMEKEEKLCIKIL	ITPR2	1661	Q14571
ENLCKLMKEILDKKV	HSP90AB1	561	P08238
LCKLMKEILDKKVEK	HSP90AB3P	436	Q58FF7
LCKIMKDMLEKKVKK	HSP90AA5P	256	Q58FG0
KEILMLKDKLEKSKR	CDC42BPB	731	Q9Y5S2
LCKIMKDILEKKVEK	HSP90AA1	571	P07900
KEKMKRKGCALLVKL	MAP4K1	476	Q92918
MLLKKKEECMKKIRE	SMC3	931	Q9UQE7
EKKLKIILEEMKEKF	SKIL	341	P12757
LLRDEKKMEKLKQKL	TLN1	151	Q9Y490
KMEEKEALVKLLLKL	SLF1	16	Q9BQI6
LKKREEMKLKECVSI	TNFSF13B	16	Q9Y275