Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
Pubmed

Pitt-Hopkins syndrome-associated mutations in TCF4 lead to variable impairment of the transcription factor function ranging from hypomorphic to dominant-negative effects.

TCF4 NEUROD2

1.94e-06249222460224
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SECISBP2L HIVEP3 RANBP10 MINAR1 CGNL1 PLEKHH2 PLCH1

5.66e-0649349715368895
Pubmed

VGLL4 targets a TCF4-TEAD4 complex to coregulate Wnt and Hippo signalling in colorectal cancer.

TCF4 VGLL4

1.16e-05449228051067
Pubmed

Heterozygosity for nuclear factor one x affects hippocampal-dependent behaviour in mice.

NFIX PROX1

1.94e-05549223776487
Pubmed

A census of human transcription factors: function, expression and evolution.

HIVEP3 TCF4 NEUROD2 PHF20 NFIX ADNP2 SRY PROX1

3.66e-0590849819274049
Pubmed

Loss of Primary Cilia Protein IFT20 Dysregulates Lymphatic Vessel Patterning in Development and Inflammation.

PODXL PROX1

4.07e-05749234055805
Pubmed

E protein dosage influences brain development more than family member identity.

TCF4 NEUROD2

5.42e-05849218214987
Pubmed

The basic helix-loop-helix transcription factor TCF4 impacts brain architecture as well as neuronal morphology and differentiation.

TCF4 PROX1

6.96e-05949231919899
Pubmed

Pogz deficiency leads to transcription dysregulation and impaired cerebellar activity underlying autism-like behavior in mice.

NEUROD2 PROX1

1.75e-041449233203851
Pubmed

bHLH gene expression in the Emx2-deficient dentate gyrus reveals defective granule cells and absence of migrating precursors.

NEUROD2 PROX1

1.75e-041449215084498
Pubmed

Loss of Axin2 Causes Ocular Defects During Mouse Eye Development.

TCF4 PROX1

2.02e-041549227701636
Pubmed

Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation.

PODXL PROX1

2.61e-041749222306086
Pubmed

NFIX regulates neural progenitor cell differentiation during hippocampal morphogenesis.

NFIX PROX1

2.93e-041849223042739
Pubmed

Genetic analysis of anterior posterior expression gradients in the developing mammalian forebrain.

TCF4 NFIX

2.93e-041849217150988
Pubmed

Genome-wide identification of FOXL2 binding and characterization of FOXL2 feminizing action in the fetal gonads.

SRY ITPR2

3.27e-041949230212841
Pubmed

Molecular evolution of Sry and Sox gene.

TCF4 SRY

3.64e-042049211404013
Pubmed

Molecular characterization of a novel transcription factor that controls stromelysin expression.

TCF4 PROX1

3.64e-04204927760812
Pubmed

Severe defects in dorsal thalamic development in low-density lipoprotein receptor-related protein-6 mutants.

TCF4 PROX1

4.41e-042249215342729
Pubmed

Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53.

NEUROD2 PROX1

4.41e-042249219020049
Pubmed

Ascending Vasa Recta Are Angiopoietin/Tie2-Dependent Lymphatic-Like Vessels.

PODXL PROX1

4.83e-042349229237738
Pubmed

A human MAP kinase interactome.

MAP1A ADNP2 CGNL1 CPLANE1 RNF111

6.00e-0448649520936779
Pubmed

Deletion of Wt1 during early gonadogenesis leads to differences of sex development in male and female adult mice.

PODXL SRY

6.67e-042749235704566
Pubmed

NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure.

SLC4A3 RASGRP2

6.67e-042749223359859
Pubmed

Emx2 and Pax6 function in cooperation with Otx2 and Otx1 to develop caudal forebrain primordium that includes future archipallium.

TCF4 PROX1

7.18e-042849215917450
Pubmed

A genetic linkage map of mouse chromosome 2 extending from thrombospondin to paired box gene 1, including the H3 minor histocompatibility complex.

MAP1A CHRNA1

7.71e-04294928617512
Pubmed

Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.

NEUROD2 PROX1

8.25e-043049230127719
Pubmed

Identification of the COMM-domain containing protein 1 as specific binding partner for the guanine-rich RNA sequence binding factor 1.

HIVEP3 NEUROD2

8.25e-043049232645484
Pubmed

The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex.

UNC5D PROX1

8.25e-043049219409883
Pubmed

Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6.

TCF4 PROX1

8.81e-043149221985497
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MAP1A ADNP2 ZZEF1 UNC5D ADCY9 PROX1 ALG13

9.10e-04111649731753913
Pubmed

A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties.

TCF4 UNC5D

9.39e-043249224192035
Pubmed

Delayed maturation and migration of excitatory neurons in the juvenile mouse paralaminar amygdala.

NEUROD2 PROX1

1.32e-033849238086370
Pubmed

Defining the molecular character of the developing and adult kidney podocyte.

PODXL PLEKHH2

1.39e-033949221931791
Pubmed

Transcriptional network orchestrating regional patterning of cortical progenitors.

TCF4 NFIX

1.39e-033949234921112
GeneFamilyTudor domain containing

PHF20 ALG13

1.49e-0337282780
GeneFamilyEF-hand domain containing

PLCH1 ZZEF1 RASGRP2

4.59e-03219283863
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

CDK17 TCF4 PODXL VGLL4 CGNL1 ITPR2

5.38e-08189486c81787a8c662db5d7814c583dd64562857629e81
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

CDK17 TCF4 PODXL CGNL1 ITPR2

1.83e-0618948575c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CGNL1 PLEKHH2 SDC1 PROX1 ITPR2

1.98e-06192485ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

TCF4 NEUROD2 NFIX UNC5D PROX1

2.30e-06198485de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Intermediate|GW26 / Sample Type, Dataset, Time_group, and Cell type.

NEUROD2 PODXL CGNL1 VWA7

5.84e-0610948448f675d36fece070410eb9cfe64805f4629e290f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 CDK17 TCF4 PODXL

2.28e-05154484e51a5114f0ec38f997f5b8bbf3a7770f98595474
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Gpc3_Slc18a3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAM184B TCF4 C3orf70 PROX1

2.85e-05163484ec9a20cfe0d69430f9c68cddd1ab0e4a3e4554b8
ToppCellEndothelial-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

TCF4 PODXL C3orf70 PROX1

3.14e-051674846a03d16165e0b003092c39972928981abd4a75aa
ToppCellNS-moderate-d_07-13-Myeloid-pDC|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TCF4 MAP1A FUT7 SLC4A3

3.21e-05168484d03e91f0e0518b33555c0ec98124fc5ed0f11be5
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

TCF4 MAP1A FUT7 SLC4A3

3.21e-05168484dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCell3'_v3-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

TCF4 C3orf70 PLCH1 ITPR2

3.29e-05169484241644823e6f949aaf4c671d4579721d7ef6b0e5
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TCF4 MAP1A FUT7 SLC4A3

3.36e-05170484b49f7c8a27078de2137ed04f74cfee30729cfa5e
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TCF4 MAP1A FUT7 SLC4A3

3.36e-0517048492e765ae0d3adb38d3b22fddb873fd5ccad3fd44
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TCF4 MAP1A FUT7 SLC4A3

3.36e-051704849f8b215caa1afa3cd7104c06fca7cfd790640f66
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TCF4 MAP1A FUT7 SLC4A3

3.44e-051714844fd2c7977c512c51507f055fc74b111c0228ed8b
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Chat_Htr1f|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAM184B TCF4 CGNL1 PROX1

3.44e-05171484f9ae7964a3740f559431125c17c660549798cccc
ToppCell368C-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CDK17 TCF4 MAP1A FUT7

3.44e-05171484714a0b0d0c9886fef64170cf53eb64f0d8a47280
ToppCellICU-SEP-Myeloid-pDC|ICU-SEP / Disease, Lineage and Cell Type

TCF4 MAP1A MINAR1 SLC4A3

3.44e-0517148472c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCDC168 PLEKHH2 PLCH1 UNC5D

3.44e-051714849d5cabd71a901a00eb16c4d151189296f1b3bf6f
ToppCellEndothelial-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

TCF4 TXLNB PODXL PROX1

3.52e-05172484d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCDC168 PLEKHH2 PLCH1 UNC5D

3.60e-051734848335b77f730ed43fc348a005566e73a103c6774b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCDC168 PLEKHH2 PLCH1 UNC5D

3.68e-05174484ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAM184B UMODL1 PLCH1 ITPR2

3.76e-051754841d8da48236549c01381f777ce5b2937f9f86acc2
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TCF4 MAP1A FUT7 SLC4A3

3.76e-0517548497fe431f224b592b3076632d101e19136c138dcc
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCDC168 PLEKHH2 PLCH1 UNC5D

3.94e-05177484f902600c639087664316b3cf30cab243bc3d1c5c
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCDC168 PLEKHH2 PLCH1 UNC5D

4.02e-051784840e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCDC168 PLEKHH2 PLCH1 UNC5D

4.11e-051794848766a5a066091879f521acfc612abf563ff78808
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

GALNT15 CDK17 TCF4 PODXL

4.11e-051794841ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCellCOPD-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

HIVEP3 TCF4 MAP1A FUT7

4.11e-0517948429b058c5e33fda9f0d738c074bdb67ff16b9b6d5
ToppCellASK454-Endothelial-Lymphatic|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

TCF4 FAM193A TXLNB PROX1

4.11e-05179484fd84a79f76a01c0377dff5b20016b004d369f96f
ToppCellCOVID-19-kidney-PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

GALNT15 CDK17 TCF4 PODXL

4.20e-05180484493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCellmoderate-Myeloid-pDC|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TCF4 MAP1A SLC4A3 RASGRP2

4.20e-05180484a0751ad5e42a21cb107d900abfa9ee967a0069fc
ToppCellNS-moderate-d_16-33-Myeloid-pDC|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TCF4 MAP1A FUT7 RASGRP2

4.20e-05180484144818e69613296cde43f29cb8c20899c670b319
ToppCelltumor_Lung-Myeloid_cells-pDCs|tumor_Lung / Location, Cell class and cell subclass

TCF4 MAP1A FUT7 SLC4A3

4.29e-05181484c864ffeb9234b8c29754afc91c85a972889617f4
ToppCellmetastatic_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

TCF4 MAP1A FUT7 SLC4A3

4.39e-0518248402e04294fce12591c32d7bd0e866a000ad1f836e
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-pDC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TCF4 MAP1A FUT7 SLC4A3

4.39e-0518248402c0824373a0ecebc922d4ca848ace9d570722c4
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 CDK17 TCF4 PODXL

4.48e-05183484dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 CDK17 TCF4 PODXL

4.48e-051834844759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCellnormal_Lung-B_lymphocytes-GrB-secreting_B_cells|normal_Lung / Location, Cell class and cell subclass

TCF4 MAP1A FUT7 SLC4A3

4.48e-05183484c930b957d16f9b0904b6c424acd914532e5cc137
ToppCell(7)_DC_plasmacytoid|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

TCF4 MAP1A FUT7 SLC4A3

4.48e-051834842c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCellURO-Myeloid-pDC|URO / Disease, Lineage and Cell Type

TCF4 MAP1A FUT7 SLC4A3

4.58e-051844840edb5dd003c2bca0b9e3ec18d03610d68bd52538
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

GALNT15 CDK17 TCF4 PODXL

4.67e-05185484673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCDC168 PLEKHH2 PLCH1 ITPR2

4.67e-051854845a0340c25196453f19e424d346efbf66d2c53ac3
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SECISBP2L HIVEP3 ZZEF1 ITPR2

4.77e-0518648474c238759c5d3fd39127ec0060d0c2cb16b326d4
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-plasmacytoid_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TCF4 MAP1A FUT7 SLC4A3

4.77e-05186484a07694caf7fede06a47636725bcc7f09909cdf07
ToppCellMultiple_Sclerosis-Myeloid-pDC|Multiple_Sclerosis / Disease, Lineage and Cell Type

TCF4 MAP1A FUT7 SLC4A3

4.77e-05186484330a4f669adea91ff9f2dff2de2210f5e3401e19
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PODXL VGLL4 CGNL1 PLCH1

4.87e-051874847e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SECISBP2L HIVEP3 ZZEF1 ITPR2

4.87e-05187484816d37a70f7ec382a268fe828b3dfe737a36a4bf
ToppCellcontrol-pDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TCF4 MAP1A FUT7 SLC4A3

4.87e-05187484c78aee98b32719aa45811b620fc97be1ecf5fd53
ToppCellPBMC-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

TCF4 MAP1A FUT7 SLC4A3

4.98e-0518848489411c4db3df5e1dc36cf8af4ffcc0abbecbe4df
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-plasmacytoid_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TCF4 MAP1A FUT7 SLC4A3

4.98e-0518848426405ef1b934744e672c642db78834c21d3ba28f
ToppCellPBMC-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

TCF4 MAP1A FUT7 SLC4A3

4.98e-05188484de6a270b6e4fe09c39a52c296632d86ada98465b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 CDK17 TCF4 PODXL

4.98e-05188484c2c51c6526defe2600302901159b8abbb58d7595
ToppCellPBMC-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TCF4 MAP1A FUT7 SLC4A3

4.98e-05188484879054b780378ae05be68e597c77c931bf0ade03
ToppCellPBMC-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TCF4 MAP1A FUT7 SLC4A3

5.08e-05189484209cae68d78c8f72479b169e27c3ff7e143adece
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-pDC|lymph-node_spleen / Manually curated celltypes from each tissue

TCF4 MAP1A FUT7 SLC4A3

5.08e-051894846c2ace61a7d62bcf7e76b73e2da8b722d03e713b
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

TCF4 PODXL CGNL1 ITPR2

5.08e-051894847346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCellPBMC-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TCF4 MAP1A FUT7 SLC4A3

5.08e-05189484a9ad1fb12304541f909dd0eeac9b9eb28c31fd41
ToppCellCOVID-19_Mild-Myeloid-pDC|COVID-19_Mild / Disease group, lineage and cell class

TCF4 MAP1A FUT7 SLC4A3

5.08e-05189484c6cfd6aa21c19f2c62d80218bbc924e14e82aada
ToppCellPBMC-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TCF4 MAP1A FUT7 SLC4A3

5.08e-0518948498ca646231fbd5f29827c2dd31ac4503026bad7d
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|kidney / Disease (COVID-19 only), tissue and cell type

GALNT15 CDK17 TCF4 PODXL

5.18e-051904841519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCellmyeloid-pDC|World / Lineage and Cell class

TCF4 MAP1A FUT7 SLC4A3

5.18e-0519048488c42779ce2f817d28e672d83f3f1158581edf73
ToppCellBLOOD--(3)_MNP-(3)_DC_(cDC+pDC)|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TCF4 MAP1A FUT7 SLC4A3

5.18e-051904849b8de47f7a2e6137d934ccce32417ab15eb54f46
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 HIVEP3 TCF4 PODXL

5.29e-05191484f663131a4810584c5854bd64ee7991a237b7707f
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TCF4 PODXL CGNL1 ITPR2

5.29e-05191484adb2e3efcad02889d8229325080da5e7830fd3ae
ToppCellCOVID-19-kidney-Stressed_EC|kidney / Disease (COVID-19 only), tissue and cell type

GALNT15 CDK17 TCF4 PODXL

5.29e-05191484d35aa842b813ea0eff7362abc894cca4e86b2fb2
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

GALNT15 CDK17 TCF4 PODXL

5.29e-051914842f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 TCF4 PODXL C3orf70

5.51e-05193484456aa8a8f1f9cbba0bd618a5f623909079c0f56b
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

TCF4 PODXL VGLL4 CGNL1

5.51e-051934842531266bc57339d4e2b22a88817008e32b8c1598
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

GALNT15 CDK17 TCF4 PODXL

5.51e-05193484479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCellnormal-na-Myeloid-plasmacytoid_dendritic_cell-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

TCF4 MAP1A FUT7 SLC4A3

5.62e-0519448474545942aded51a0f4ee96054b4ce12c4d99a8a0
ToppCellnormal-na-Myeloid-plasmacytoid_dendritic_cell|normal / PBMC cell types (v2) per disease, treatment status, and sex

TCF4 MAP1A FUT7 SLC4A3

5.62e-05194484c25fc353001cdf9fcd772da5a254c857e555eab8
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TCF4 NFIX CHRNA1 PROX1

5.62e-051944848b81f039f5b25d35a4d5a41b27d4d9360ba22f15
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 HIVEP3 TCF4 PODXL

5.62e-05194484b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCell10x5'-bone_marrow-Myeloid_Dendritic|bone_marrow / Manually curated celltypes from each tissue

TCF4 MAP1A FUT7 SLC4A3

5.62e-05194484768271ae45ff9f6aa3cd9b0ed15fa3caaa68a7b0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 HIVEP3 TCF4 PODXL

5.62e-05194484fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

GALNT15 CDK17 TCF4 PODXL

5.73e-05195484a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 CDK17 TCF4 PODXL

5.73e-051954846bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 TCF4 PODXL C3orf70

5.73e-0519548423ced69fd904f1d4114b1a7f99f4b5f65ea8824b
ToppCellmild-B_cell|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CDK17 TCF4 ZZEF1 USP21

5.73e-051954841e5f1967bcc898318f4e970b844b4a944eb168e5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 CDK17 TCF4 PODXL

5.73e-05195484d35102f95bb1e419d2df05ff0a01b6c5c923acef
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38|World / Primary Cells by Cluster

TCF4 NEUROD2 NFIX UNC5D

5.85e-0519648438da0751941adca650fe9b383d9f343153978eb5
ToppCelldistal-Hematologic-Plasmacytoid_Dendritic-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NEUROD2 MAP1A FUT7 SLC4A3

5.85e-05196484170629b9ae82e9a911b93e8739dcd38176fbecb4
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 CDK17 TCF4 PODXL

5.85e-051964848f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn|World / Primary Cells by Cluster

TCF4 NEUROD2 NFIX UNC5D

5.85e-05196484721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn|World / Primary Cells by Cluster

TCF4 NEUROD2 NFIX UNC5D

5.85e-051964849401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 CDK17 TCF4 PODXL

5.85e-05196484b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 CDK17 TCF4 PODXL

5.85e-05196484145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 HIVEP3 TCF4 PODXL

5.85e-05196484adee900dcd16dbaba15c58bdcace09ba20214950
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

GALNT15 CDK17 TCF4 PODXL

5.85e-05196484b71b197cb92117dd9efaa13de000841901cc4ca8
ToppCelldistal-3-Hematologic-Plasmacytoid_Dendritic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TCF4 MAP1A FUT7 SLC4A3

5.85e-051964846028b790abba9bad1d5373bab13eb24855988f48
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 CDK17 TCF4 PODXL

5.85e-05196484d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCellmedial-Hematologic-Myeloid_Dendritic_Type_1|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRABD2A FUT7 SLC4A3 CHRNA1

5.97e-051974845bd2f32137fd849931e52093d630d2e7e27daf4f
ToppCellmedial-Hematologic-Myeloid_Dendritic_Type_1-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRABD2A FUT7 SLC4A3 CHRNA1

5.97e-05197484d9baa0be469fd8737a74b5078d30ce7d66759160
ToppCelldistal-Hematologic-Plasmacytoid_Dendritic-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TCF4 MAP1A FUT7 SLC4A3

5.97e-051974843a5908deb5c5a2bf06019a102fb1652233cf2a2a
ToppCelldistal-1-Hematologic-Plasmacytoid_Dendritic|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TCF4 MAP1A FUT7 SLC4A3

5.97e-05197484166d47359df9279ea8c3946f10bd3d4b88c95857
ToppCellmedial-2-Hematologic-Myeloid_Dendritic_Type_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRABD2A FUT7 SLC4A3 CHRNA1

5.97e-051974843c1147857de6a7ab6b0cf77f5a6364d4c8669693
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 HIVEP3 TCF4 PODXL

6.08e-0519848407701c73137947ed4a27e225975329235bbb8734
ToppCellBiopsy_IPF-Immune-pDCs|Biopsy_IPF / Sample group, Lineage and Cell type

TCF4 MAP1A FUT7 SLC4A3

6.08e-05198484aa8943e6796f619406056cf763b751fe9a9a3e0c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 HIVEP3 TCF4 PODXL

6.08e-0519848431ba87552be97c9b78c9e82f98e96699ccb19824
DrugAG-013608 [351320-38-2]; Up 200; 10uM; PC3; HT_HG-U133A

DHRS12 PHF20 PLCH1 FUT7 CPLANE1 ITPR2

3.23e-061944865909_UP
Diseasecoffee consumption measurement, insomnia

TCF4 PODXL

1.06e-0410462EFO_0004698, EFO_0006781
Diseaserefractive error

GALNT15 HIVEP3 NEUROD2 ZZEF1 ITPR2

1.51e-04326465MONDO_0004892
DiseaseNeurodevelopmental Disorders

HIVEP3 TCF4 ALG13

4.17e-0493463C1535926
Diseasealcohol use disorder measurement, alcohol consumption measurement

GALNT15 TCF4 PLCH1

4.72e-0497463EFO_0007878, EFO_0009458
Diseasesex interaction measurement, cerebral amyloid angiopathy

GALNT15 ADCY9

4.90e-0421462EFO_0006790, EFO_0008343
DiseaseAbnormality of refraction

GALNT15 HIVEP3 TCF4 NFIX ZZEF1 ITPR2

5.93e-04673466HP_0000539
Diseasetestosterone measurement

GALNT15 FAM184B MAP1A MINAR1 SDC1 UNC5D ADCY9 PROX1

7.17e-041275468EFO_0004908
Diseasecortex volume change measurement, age at assessment

VGLL4 CGNL1

8.76e-0428462EFO_0008007, EFO_0021500
DiseaseHeart Diseases

TCF4 SLC4A3

2.36e-0346462C0018799
Diseasebody mass index, fasting blood glucose measurement

ADCY9 PROX1

2.89e-0351462EFO_0004340, EFO_0004465
Diseaseobesity (implicated_via_orthology)

TCF4 PROX1 ITPR2

4.60e-03215463DOID:9970 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
LQPMASTVHHLHSAP

UMODL1

206

Q5DID0
PSSSSMNSVLGNHHP

SLC4A3

441

P48751
MNSVLGNHHPTPSHG

SLC4A3

446

P48751
VMSNEHFHPQHPSPR

ALG13

636

Q9NP73
GNSQFVHPSHHPEIM

ABHD11

266

Q8NFV4
APHSHRMSPEEVSAH

C3orf70

151

A6NLC5
TSSHSPSRHMNHSEP

FAM193A

981

P78312
HSPPAAGQSHMTLVS

ADNP2

321

Q6IQ32
MHHRTPSMHNQSHVP

IGDCC4

616

Q8TDY8
PSLSPRHGPSSSHMH

RANBP10

366

Q6VN20
FLGSNTPHVNHHMPP

ITPR2

2686

Q14571
INTHHRSPSTHVMPN

CHRNA1

316

P02708
HPVATPTSSGHDHLM

PODXL

196

O00592
SDSHIQRAPHPPNMH

KIAA0100

476

Q14667
SSQGSSPRMAFTHHP

NFIX

336

Q14938
TSHHTAPMSVPEPHA

MAP1A

1246

P78559
PMHSHHHRAFSFSLP

RASGRP2

566

Q7LDG7
SLPPMSTFHRSGTNH

TCF4

276

P15884
AMSHRNRSFSFNPHP

FAM184B

941

Q9ULE4
AMLHPPHHTLHQTVT

GALNT15

31

Q8N3T1
PGHPASSLHFMHADA

CSKMT

131

A8MUP2
MESPSHTHGLSHLRG

FUT7

121

Q11130
HFHSAFKSMAHSPGP

MICAL1

606

Q8TDZ2
GRPPTSHSMHSFLHQ

CDK17

46

Q00537
HHSLPFSIPVHFMNG

PLEKHH2

1116

Q8IVE3
MTHPLPHDSHTSGAP

GSN-AS1

1

Q9NRJ2
AFSHPGHTTPQSMQV

CPLANE1

1971

Q9H799
FTSGRPLTAHSPHAH

CGNL1

251

Q0VF96
THQDMARGPGLPHTH

LINC00315

76

P59091
AQGHPAIHFSSMHPG

DHRS12

216

A0PJE2
MASPPHQQLLHHHST

ADCY9

1

O60503
KTHPFMPSLSHHRFS

CCDC168

4826

Q8NDH2
SSHKPGVHMSPQLHG

PHF20

581

Q9BVI0
PRMFHAHSGSHGPKL

MINAR1

661

Q9UPX6
QPGLSAHMAPAHQHS

RNF165

61

Q6ZSG1
TKMSSHHLSHHPCSP

PROX1

526

Q92786
SHPHRDMQPGHHETS

SDC1

151

P18827
PHHMGHSRNPSAASA

SECISBP2L

841

Q93073
SPAGPHHHRPRMAST

SPATA31E1

1411

Q6ZUB1
QPASPSAHMVSHSHS

VGLL4

271

Q14135
PPASHGSFHMISARS

USP21

176

Q9UK80
GHHIHVPQTMSSHPR

RNF111

786

Q6ZNA4
TMSHHPAASHDGAQP

FAM90A2P

376

Q658T7
LGTHMLTVPSHHPHA

HIVEP3

971

Q5T1R4
LPRRGHSHHSQMVAS

TRABD2A

466

Q86V40
PHGNNHSFSTMHPRN

UNC5D

511

Q6UXZ4
HLHNTSVMSGHCPLP

PLCH1

1216

Q4KWH8
YGHLPTHSITAHPMV

ZZEF1

1866

O43149
ATHSRMEHQLGHLPP

SRY

171

Q05066
AFMIIHHPESTPHQS

TXLNB

506

Q8N3L3
TSPGFSPHHMLHLQA

VWA7

266

Q9Y334
SMHYSALPGSRPTGH

NEUROD2

326

Q15784