Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
HumanPhenoSporadic

HNF1B NFIA NFIX FLCN CHD7 NIPBL

1.29e-06103196HP:0003745
HumanPhenoAbnormal stomach morphology

CACNA1A GABRG2 HNF1B FOXP2 NFIX FLCN KCNQ3 CHD7 PEX11B NIPBL FOXP3

1.44e-057421911HP:0002577
HumanPhenoFacial tics

CACNA1A GABRG2 KCNQ3

1.95e-0515193HP:0011468
HumanPhenoPhotosensitive tonic-clonic seizure

GABRG2 CLCN2 KCNQ3

1.95e-0515193HP:0007207
HumanPhenoVisually-induced seizure

GABRG2 CLCN2 KCNQ3

3.47e-0518193HP:0020216
HumanPhenoReflex seizure

GABRG2 CLCN2 KCNQ3

6.48e-0522193HP:0020207
HumanPhenoHypoplasia of the semicircular canal

FOXP2 CHD7

7.87e-054192HP:0011382
HumanPhenoInfection-related seizure

CACNA1A GABRG2 CLCN2 NFIX KCNQ3

1.47e-04145195HP:0032892
HumanPhenoSeizure precipitated by febrile infection

CACNA1A GABRG2 CLCN2 NFIX KCNQ3

1.47e-04145195HP:0032894
HumanPhenoFebrile seizure (within the age range of 3 months to 6 years)

CACNA1A GABRG2 CLCN2 NFIX KCNQ3

1.47e-04145195HP:0002373
HumanPhenoOverfolded helix

FOXP2 NFIA NFIX CHD7

2.01e-0482194HP:0000396
HumanPhenoDisinhibition

CACNA1A GABRG2 CLCN2 FOXP2 NFIA NFIX FLCN KCNQ3 CHD7 NIPBL

2.22e-048071910HP:0000734
HumanPhenoInappropriate behavior

CACNA1A GABRG2 CLCN2 FOXP2 NFIA NFIX FLCN KCNQ3 CHD7 NIPBL

2.22e-048071910HP:0000719
HumanPhenoAbnormal response to social norms

CACNA1A GABRG2 CLCN2 FOXP2 NFIA NFIX FLCN KCNQ3 CHD7 NIPBL

2.22e-048071910HP:5200123
HumanPhenoSocial disinhibition

CACNA1A GABRG2 CLCN2 FOXP2 NFIA NFIX FLCN KCNQ3 CHD7 NIPBL

2.22e-048071910HP:5200029
HumanPhenoAutism

CACNA1A GABRG2 HNF1B FLCN CHD7 NIPBL

2.80e-04264196HP:0000717
HumanPhenoAbnormally folded helix

FOXP2 NFIA NFIX CHD7

2.88e-0490194HP:0008544
HumanPhenoDisturbance of facial expression

CACNA1A GABRG2 KCNQ3

2.91e-0436193HP:0005324
HumanPhenoGastroesophageal reflux

CACNA1A GABRG2 FOXP2 NFIX FLCN KCNQ3 CHD7 NIPBL

2.92e-04517198HP:0002020
HumanPhenoReduced impulse control

CACNA1A GABRG2 HNF1B CLCN2 FOXP2 NFIA NFIX FLCN KCNQ3 CHD7 NIPBL

3.39e-0410321911HP:5200045
HumanPhenoAbnormally increased volition

CACNA1A GABRG2 CLCN2 FOXP2 NFIA NFIX FLCN KCNQ3 CHD7 NIPBL

4.16e-048691910HP:5200263
HumanPhenoHyperactivity

CACNA1A GABRG2 FOXP2 NFIA NFIX FLCN CHD7 NIPBL

4.96e-04558198HP:0000752
HumanPhenoPyloric stenosis

HNF1B NFIX PEX11B NIPBL

5.02e-04104194HP:0002021
HumanPhenoAbnormality of the pylorus

HNF1B NFIX PEX11B NIPBL

5.59e-04107194HP:0004400
HumanPhenoAbnormal social development

CACNA1A GABRG2 CLCN2 FOXP2 NFIA NFIX FLCN KCNQ3 CHD7 NIPBL

6.00e-049081910HP:0025732
MousePhenoabnormal corpus callosum morphology

CLCN2 NFIA NFIX CHD7 NIPBL

5.63e-05129455MP:0000780
MousePhenoabnormal dorsal telencephalic commissure morphology

CLCN2 NFIA NFIX CHD7 NIPBL

6.28e-05132455MP:0008219
MousePhenoabnormal lower incisor morphology

NFIC TNN WWP2

6.82e-0525453MP:0030136
MousePhenoabnormal nervous system electrophysiology

CACNA1A GABRG2 TRPV1 CLCN2 NUP155 KCNQ3 CHD7

7.89e-05329457MP:0002272
MousePhenolethality at weaning

CACNA1A GABRG2 NFIX FOXP3

1.50e-0484454MP:0008569
MousePhenodelayed eyelid opening

FOXP2 NFIX FOXP3

1.59e-0433453MP:0001290
MousePhenoabnormal brain commissure morphology

CLCN2 NFIA NFIX CHD7 NIPBL

1.60e-04161455MP:0002199
MousePhenodilated third ventricle

NFIA NFIX CHD7

1.74e-0434453MP:0000827
MousePhenoabnormal retrosplenial region morphology

NFIX CHD7

2.11e-047452MP:0012489
MousePhenoabnormal cerebellum morphology

CACNA1A CLCN2 FOXP2 NFIA CHD7 PEX11B NIPBL

2.23e-04389457MP:0000849
MousePhenoabnormal cerebellum development

CACNA1A FOXP2 NFIA CHD7

2.51e-0496454MP:0000854
MousePhenoabnormal nervous system tract morphology

CLCN2 NFIA NFIX CHD7 NIPBL

3.38e-04189455MP:0000778
MousePhenoabnormal metencephalon morphology

CACNA1A CLCN2 FOXP2 NFIA CHD7 PEX11B NIPBL

3.55e-04420457MP:0000847
MousePhenoabnormal righting response

CACNA1A GABRG2 TRPV1 FOXP2 CHD7

3.90e-04195455MP:0002862
MousePhenolethality at weaning, complete penetrance

CACNA1A GABRG2 FOXP3

4.30e-0446453MP:0011083
MousePhenoabnormal cingulate gyrus morphology

NFIX CHD7

4.49e-0410452MP:0004167
MousePhenoabnormal postural reflex

CACNA1A GABRG2 TRPV1 FOXP2 CHD7

4.68e-04203455MP:0002980
MousePhenoabnormal neocortex morphology

NFIX CHD7 PEX11B

4.87e-0448453MP:0008547
MousePhenoabnormal brain white matter morphology

CLCN2 NFIA NFIX CHD7 NIPBL

5.01e-04206455MP:0008026
DomainNfI_DNAbd_pre-N

NFIA NFIC NFIX

8.61e-084533PF10524
DomainCTF_NFI

NFIA NFIC NFIX

8.61e-084533PF00859
DomainCTF_NFI_1

NFIA NFIC NFIX

8.61e-084533PS00349
DomainFOXP-CC

FOXP4 FOXP2 FOXP3

8.61e-084533PF16159
DomainFOXP-CC

FOXP4 FOXP2 FOXP3

8.61e-084533IPR032354
DomainCTF/NFI

NFIA NFIC NFIX

8.61e-084533IPR000647
DomainCTF_NFI_2

NFIA NFIC NFIX

8.61e-084533PS51080
DomainCTF/NFI_DNA-bd_N

NFIA NFIC NFIX

8.61e-084533IPR019548
DomainCTF/NFI_DNA-bd_CS

NFIA NFIC NFIX

8.61e-084533IPR019739
DomainCTF/NFI_DNA-bd-dom

NFIA NFIC NFIX

8.61e-084533IPR020604
DomainMAD_homology1_Dwarfin-type

NFIA NFIC NFIX

4.66e-0612533IPR003619
DomainDWA

NFIA NFIC NFIX

4.66e-0612533SM00523
DomainMH1

NFIA NFIC NFIX

4.66e-0612533PF03165
DomainTF_fork_head_CS_2

FOXJ2 FOXP4 FOXP2 FOXP3

8.63e-0646534IPR030456
DomainTF_fork_head_CS_1

FOXJ2 FOXP4 FOXP2 FOXP3

9.42e-0647534IPR018122
DomainFH

FOXJ2 FOXP4 FOXP2 FOXP3

1.11e-0549534SM00339
DomainFORK_HEAD_1

FOXJ2 FOXP4 FOXP2 FOXP3

1.11e-0549534PS00657
DomainFORK_HEAD_2

FOXJ2 FOXP4 FOXP2 FOXP3

1.11e-0549534PS00658
DomainFork_head_dom

FOXJ2 FOXP4 FOXP2 FOXP3

1.11e-0549534IPR001766
DomainFORK_HEAD_3

FOXJ2 FOXP4 FOXP2 FOXP3

1.11e-0549534PS50039
DomainForkhead

FOXJ2 FOXP4 FOXP2 FOXP3

1.11e-0549534PF00250
DomainssDNA-bd_transcriptional_reg

NFIC NFIX

2.37e-053532IPR009044
DomainWHTH_DNA-bd_dom

FOXJ2 CUL1 FOXP4 FOXP2 SNRNP200 FOXP3

6.14e-05242536IPR011991
Domain-

FOXJ2 CUL1 FOXP4 FOXP2 FOXP3

3.76e-042185351.10.10.10
DomainFibrinogen_CS

ANGPTL2 TNN

1.31e-0319532IPR020837
DomainFibrinogen_a/b/g_C_2

ANGPTL2 TNN

2.10e-0324532IPR014715
Domain-

ANGPTL2 TNN

2.10e-03245324.10.530.10
DomainHECT

WWP2 HECTD1

2.65e-0327532PF00632
DomainHECTc

WWP2 HECTD1

2.65e-0327532SM00119
DomainHECT_dom

WWP2 HECTD1

2.65e-0327532IPR000569
DomainHECT

WWP2 HECTD1

2.65e-0327532PS50237
DomainFibrinogen_C

ANGPTL2 TNN

2.65e-0327532PF00147
DomainFBG

ANGPTL2 TNN

3.05e-0329532SM00186
Domain-

ANGPTL2 TNN

3.27e-03305323.90.215.10
DomainFibrinogen_a/b/g_C_1

ANGPTL2 TNN

3.27e-0330532IPR014716
DomainFIBRINOGEN_C_1

ANGPTL2 TNN

3.71e-0332532PS00514
DomainFibrinogen_a/b/g_C_dom

ANGPTL2 TNN

3.71e-0332532IPR002181
DomainFIBRINOGEN_C_2

ANGPTL2 TNN

3.71e-0332532PS51406
DomainIon_trans_dom

CACNA1A TRPV1 KCNQ3

4.16e-03114533IPR005821
DomainIon_trans

CACNA1A TRPV1 KCNQ3

4.16e-03114533PF00520
DomainMFS_dom

SLC37A1 SLC43A3 SLC15A3

6.51e-03134533IPR020846
DomainAAA+_ATPase

ABCA6 RNF213 SNRNP200

7.94e-03144533IPR003593
DomainAAA

ABCA6 RNF213 SNRNP200

7.94e-03144533SM00382
PathwayREACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_TERMINATION

NFIA NFIC NFIX

5.15e-0523453M1024
Pubmed

Nuclear factor one transcription factors as epigenetic regulators in cancer.

NFIA NFIC NFIX

1.50e-08455328076901
Pubmed

Transcription factor NF 1 expression in involuting mammary gland.

NFIA NFIC NFIX

1.50e-08455310959417
Pubmed

Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH.

NFIA NFIC NFIX

1.50e-0845537590749
Pubmed

Identification and characterization of T reg-like cells in zebrafish.

FOXP4 FOXP2 FOXP3

1.50e-08455329066577
Pubmed

Altered expression of the developmentally regulated NFI gene family during phorbol ester-induced differentiation of human leukemic cells.

NFIA NFIC NFIX

1.50e-0845539052991
Pubmed

Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development.

NFIA NFIC NFIX

1.50e-0845539056636
Pubmed

Genomic organization, splice products and mouse chromosomal localization of genes for transcription factor Nuclear Factor One.

NFIA NFIC NFIX

1.50e-08455312568726
Pubmed

Regulation of the CYP3A4 and CYP3A7 promoters by members of the nuclear factor I transcription factor family.

NFIA NFIC NFIX

3.73e-08555319706729
Pubmed

Temporal control of a dendritogenesis-linked gene via REST-dependent regulation of nuclear factor I occupancy.

NFIA NFIC NFIX

7.46e-08655321270437
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

FOXJ2 MRPS30 CUL1 FOXP4 FOXP2 NFIA NFIC NFIX MAGT1 SNRNP200 FOXP3

8.50e-08857551125609649
Pubmed

NFI in the development of the olfactory neuroepithelium and the regulation of olfactory marker protein gene expression.

NFIA NFIC NFIX

1.30e-07755310762365
Pubmed

TGF-β/NF1/Smad4-mediated suppression of ANT2 contributes to oxidative stress in cellular senescence.

NFIA NFIC NFIX

1.30e-07755325220407
Pubmed

Forkhead Box Protein P1 Is Dispensable for Retina but Essential for Lens Development.

FOXP4 FOXP2 FOXP3

4.46e-071055328384713
Pubmed

Nfix regulates fetal-specific transcription in developing skeletal muscle.

NFIA NFIC NFIX

6.12e-071155320178747
Pubmed

Nuclear factor I coordinates multiple phases of cerebellar granule cell development via regulation of cell adhesion molecules.

NFIA NFIC NFIX

1.06e-061355317553984
Pubmed

Exon structure of the nuclear factor I DNA-binding domain from C. elegans to mammals.

NFIA NFIC NFIX

2.07e-061655310087299
Pubmed

Structural analysis of disease-causing mutations in the P-subfamily of forkhead transcription factors.

FOXP2 FOXP3

2.46e-06255214997560
Pubmed

NFIA haploinsufficiency is associated with a CNS malformation syndrome and urinary tract defects.

CASS4 NFIA

2.46e-06255217530927
Pubmed

An Etiological Foxp2 Mutation Impairs Neuronal Gain in Layer VI Cortico-Thalamic Cells through Increased GABAB/GIRK Signaling.

FOXP2 FOXP3

2.46e-06255233020214
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

FOXP4 NFIA NFIC NFIX CHD7 NIPBL

4.18e-0626855633640491
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

CUL1 CACTIN NFIA NFIC NFIX AATF CHD7 MAGT1 PEX11B NIPBL SNRNP200

4.82e-061294551130804502
Pubmed

CREB binding protein coordinates the function of multiple transcription factors including nuclear factor I to regulate phosphoenolpyruvate carboxykinase (GTP) gene transcription.

NFIA NFIC

7.36e-06355210085123
Pubmed

Foxp4: a novel member of the Foxp subfamily of winged-helix genes co-expressed with Foxp1 and Foxp2 in pulmonary and gut tissues.

FOXP4 FOXP2

7.36e-06355214516685
Pubmed

Human-specific transcriptional regulation of CNS development genes by FOXP2.

FOXP4 FOXP2

7.36e-06355219907493
Pubmed

Cerebellar modules operate at different frequencies.

CACNA1A GABRG2

7.36e-06355224843004
Pubmed

Protein-Protein Interaction Among the FoxP Family Members and their Regulation of Two Target Genes, VLDLR and CNTNAP2 in the Zebra Finch Song System.

FOXP4 FOXP2

7.36e-06355228507505
Pubmed

Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors as Regulating Mitotic Exit and Late-Born Cell Specification.

NFIA NFIX

7.36e-06355231128945
Pubmed

The p53 tumor suppressor gene is regulated in vivo by nuclear factor 1-C2 in the mouse mammary gland during pregnancy.

NFIA NFIC

7.36e-06355212955085
Pubmed

Transcriptional regulation by FOXP1, FOXP2, and FOXP4 dimerization.

FOXP4 FOXP2

7.36e-06355225027557
Pubmed

NFI-B3, a novel transcriptional repressor of the nuclear factor I family, is generated by alternative RNA processing.

NFIC NFIX

7.36e-0635529099724
Pubmed

Patterned expression of ion channel genes in mouse dorsal raphe nucleus determined with the Allen Mouse Brain Atlas.

CACNA1A GABRG2 KCNQ3

7.40e-062455322534482
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

NFIA NFIC CHD7 NIPBL

9.37e-068355428794006
Pubmed

Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions.

FOXP4 FOXP2

1.47e-05455214701752
Pubmed

Differential neuronal and glial expression of nuclear factor I proteins in the cerebral cortex of adult mice.

NFIA NFIX

1.47e-05455228295292
Pubmed

Gene regulatory networks controlling vertebrate retinal regeneration.

NFIA NFIX

1.47e-05455233004674
Pubmed

Neuronal, stromal, and T-regulatory cell crosstalk in murine skeletal muscle.

TRPV1 FOXP3

1.47e-05455232102913
Pubmed

NFIA and GATA3 are crucial regulators of embryonic articular cartilage differentiation.

NFIA NFIX

1.47e-05455229247144
Pubmed

RFX1 and NF-1 associate with P sequences of the human growth hormone locus in pituitary chromatin.

NFIC NFIX

1.47e-05455212624117
Pubmed

A CACNB4 mutation shows that altered Ca(v)2.1 function may be a genetic modifier of severe myoclonic epilepsy in infancy.

CACNA1A GABRG2

1.47e-05455218755274
Pubmed

Synaptic transmission and plasticity at inputs to murine cerebellar Purkinje cells are largely dispensable for standard nonmotor tasks.

CACNA1A GABRG2

1.47e-05455223904597
Pubmed

The transcription factor gene Nfib is essential for both lung maturation and brain development.

NFIA NFIC NFIX

1.47e-053055315632069
Pubmed

Interaction network of human early embryonic transcription factors.

FOXP4 FOXP2 NFIA NFIC CHD7 NIPBL

1.93e-0535155638297188
Pubmed

A Chromatin Accessibility Atlas of the Developing Human Telencephalon.

KCNQ3 CHD7

2.45e-05555232610082
Pubmed

Control of neurogenic competence in mammalian hypothalamic tanycytes.

NFIA NFIX

2.45e-05555234049878
Pubmed

Ion channel expression in the developing enteric nervous system.

CACNA1A CLCN2 KCNQ3

2.80e-053755325798587
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

NUP155 NFIA NFIC NFIX CHD7 APOBEC3C SNRNP200

3.63e-0558355729844126
Pubmed

Generation of mice with a conditional Foxp2 null allele.

FOXP4 FOXP2

3.67e-05655217619227
Pubmed

Absence epilepsy in tottering mutant mice is associated with calcium channel defects.

CACNA1A NFIX

3.67e-0565528929530
Pubmed

Absence of the transcription factor Nfib delays the formation of the basilar pontine and other mossy fiber nuclei.

NFIA NFIX

3.67e-05655219107796
Pubmed

Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.

FOXP4 FOXP2

3.67e-05655228591638
Pubmed

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

CACNA1A GABRG2 KCNQ3

5.07e-054555325979088
Pubmed

Foxp1/2/4-NuRD interactions regulate gene expression and epithelial injury response in the lung via regulation of interleukin-6.

FOXP4 FOXP2

5.13e-05755220185820
Pubmed

Identification and characterization of transcribed enhancers during cerebellar development through enhancer RNA analysis.

CACNA1A FOXP2

5.13e-05755237365500
Pubmed

Modeled changes of cerebellar activity in mutant mice are predictive of their learning impairments.

CACNA1A GABRG2

5.13e-05755227805050
Pubmed

Expansion of the lateral ventricles and ependymal deficits underlie the hydrocephalus evident in mice lacking the transcription factor NFIX.

NFIA NFIX

6.83e-05855225960350
Pubmed

A genome-wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS-mutant melanoma.

CUL1 TAB1

6.83e-05855231549767
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

TTLL12 NUP155 AATF CHD7 HECTD1 NIPBL SNRNP200

7.40e-0565355722586326
Pubmed

A screen for downstream effectors of Neurogenin2 in the embryonic neocortex.

WWP2 FUT9 NIPBL

7.83e-055255315328020
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

CUL1 HNF1B NUP155 NFIC MAGT1 PEX11B

8.38e-0545755632344865
Pubmed

Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.

HNF1B FOXP4

1.10e-041055220676098
Pubmed

Foxp1/2/4 regulate endochondral ossification as a suppresser complex.

FOXP4 FOXP2

1.34e-041155225527076
Pubmed

A genome-wide association study of seasonal pattern mania identifies NF1A as a possible susceptibility gene for bipolar disorder.

NFIA NFIX

1.34e-041155222925353
Pubmed

Immunity to the microbiota promotes sensory neuron regeneration.

TRPV1 FOXP3

1.60e-041255236640762
Pubmed

Transcriptional regulation of Nfix by NFIB drives astrocytic maturation within the developing spinal cord.

NFIA NFIX

1.89e-041355229106906
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

NUP155 NFIA NFIC NFIX

1.93e-0418055435198878
Pubmed

Tat predominantly associates with host promoter elements in HIV-1-infected T-cells - regulatory basis of transcriptional repression of c-Rel.

FOXP4 FOXP2

2.54e-041555225472883
Pubmed

The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice.

FOXP4 FOXP2

2.90e-041655226021489
Pubmed

The ubiquitin conjugating enzyme, UbcM2, engages in novel interactions with components of cullin-3 based E3 ligases.

CUL1 KLHL42

2.90e-041655219256485
Pubmed

Identification of forkhead transcription factors in cortical and dopaminergic areas of the adult murine brain.

FOXJ2 FOXP2

2.90e-041655216376864
Pubmed

Foxp-mediated suppression of N-cadherin regulates neuroepithelial character and progenitor maintenance in the CNS.

FOXP4 FOXP2

2.90e-041655222542185
Pubmed

Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.

GABRG2 KCNQ3

3.70e-041855237321992
Pubmed

Genetic analysis of anterior posterior expression gradients in the developing mammalian forebrain.

NFIC NFIX

3.70e-041855217150988
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

CUL1 NUP155 NFIC RNF213 TAB1 APOBEC3C

3.77e-0460455638803224
Pubmed

SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.

CUL1 WWP2

4.13e-041955221572392
Pubmed

Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding.

FOXP4 NFIA

4.58e-042055234407390
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

CUL1 FLCN AATF HECTD1

5.04e-0423255425515538
Pubmed

Global analysis of genes differentially expressed in branching and non-branching regions of the mouse embryonic lung.

NFIX WWP2

5.06e-042155215328023
Pubmed

Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions.

FOXP2 WWP2

5.06e-042155229659575
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

MRPS30 CUL1 NUP155 RNF213 AATF TAB1 MAGT1 PEX11B C2CD2L

5.24e-04149655932877691
Pubmed

A census of human transcription factors: function, expression and evolution.

FOXJ2 FOXP4 FOXP2 NFIA NFIC NFIX FOXP3

5.51e-0490855719274049
Pubmed

Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates.

FOXP4 FOXP2

5.56e-042255232049024
Pubmed

Cerebellar cortical lamination and foliation require cyclin A2.

FOXP4 FOXP2

6.08e-042355224184637
Pubmed

Foxp2 and Foxp1 cooperatively regulate lung and esophagus development.

FOXP4 FOXP2

7.20e-042555217428829
Pubmed

Morphogenetic lung defects of JSAP1-deficient embryos proceeds via the disruptions of the normal expressions of cytoskeletal and chaperone proteins.

NFIA NFIX

7.20e-042555218324732
Pubmed

System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.

WWP2 HECTD1

7.79e-042655226949039
Pubmed

Foxp transcription factors suppress a non-pulmonary gene expression program to permit proper lung development.

FOXP4 FOXP2

7.79e-042655227341756
Pubmed

Cerebellar dysfunction and schizophrenia-like behavior in Ebp1-deficient mice.

CACNA1A FOXP2

7.79e-042655235165395
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

FOXJ2 FOXP4 FOXP2 FOXP3

8.05e-0426355420932939
Pubmed

Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease.

CUL1 NFIA NFIC AATF APOBEC3C

8.23e-0446355527503909
Pubmed

TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma.

NUP155 TAB1

9.04e-042855229653964
Pubmed

Proteomic analysis of FOXP proteins reveals interactions between cortical transcription factors associated with neurodevelopmental disorders.

FOXP4 FOXP2

9.04e-042855229365100
Pubmed

Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning.

NFIA NFIX

1.04e-033055223042737
Pubmed

The DNA sequence and biology of human chromosome 19.

CACNA1A CACTIN NFIC NFIX

1.07e-0328455415057824
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NFIA RNF213 PPP6R2 HECTD1 SNRNP200

1.09e-0349355515368895
Pubmed

Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.

CUL1 KLHL42 RNF213 TAB1 SNRNP200

1.11e-0349555528581483
Pubmed

Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1.

FOXP4 FOXP2

1.26e-033355218662545
Pubmed

The role of primary cilia in corpus callosum formation is mediated by production of the Gli3 repressor.

NFIA NFIX

1.26e-033355226071364
Pubmed

The DNA sequence of human chromosome 22.

TTLL12 TAB1 APOBEC3C PPP6R2

1.31e-0330055410591208
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

CACTIN NFIA NFIC CHD7 NIPBL SNRNP200

1.37e-0377455615302935
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

CUL1 NUP155 RNF213 SNRNP200

1.37e-0330455432235678
InteractionSATB2 interactions

FOXJ2 HNF1B FOXP4 FOXP2 NFIA NFIC NFIX FOXP3

1.12e-08159558int:SATB2
InteractionPAX8 interactions

HNF1B FOXP4 NFIA NFIC NFIX CHD7 NIPBL

2.07e-08111557int:PAX8
InteractionTBR1 interactions

HNF1B FOXP4 FOXP2 NFIA NFIC NFIX CHD7

2.35e-08113557int:TBR1
InteractionTLX2 interactions

HNF1B FOXP4 NFIA NFIC NFIX CHD7 NIPBL

1.14e-07142557int:TLX2
InteractionPAX2 interactions

HNF1B FOXP4 NFIA NFIC NFIX CHD7

1.16e-0785556int:PAX2
InteractionZNF148 interactions

FOXJ2 FOXP4 FOXP2 NFIA NFIC NFIX FOXP3

1.25e-07144557int:ZNF148
InteractionFOXC1 interactions

FOXJ2 HNF1B FOXP4 FOXP2 NFIA NFIC NFIX SNRNP200

1.83e-07228558int:FOXC1
InteractionSOX17 interactions

HNF1B FOXP4 NFIA NFIC NFIX CHD7

2.25e-0795556int:SOX17
InteractionSOX9 interactions

CUL1 HNF1B NFIA NFIC NFIX CHD7

2.55e-0797556int:SOX9
InteractionSOX5 interactions

HNF1B FOXP4 FOXP2 NFIA NFIC NFIX CHD7

2.79e-07162557int:SOX5
InteractionEGR2 interactions

FOXP4 FOXP2 NFIA NFIC WWP2 CHD7 NIPBL

4.03e-07171557int:EGR2
InteractionMIDEAS interactions

HNF1B NFIA NFIC NFIX WWP2 FOXP3

4.82e-07108556int:MIDEAS
InteractionARID1A interactions

CUL1 HNF1B NFIA NFIC NFIX WWP2 CHD7 FOXP3

7.80e-07276558int:ARID1A
InteractionPAX7 interactions

HNF1B FOXP4 NFIA NFIC NFIX CHD7

1.09e-06124556int:PAX7
InteractionTLX3 interactions

HNF1B FOXP4 AOC1 NFIA NFIC NFIX CHD7 NIPBL

1.16e-06291558int:TLX3
InteractionPAX9 interactions

FOXP4 NFIA NFIC NFIX CHD7 NIPBL

1.44e-06130556int:PAX9
InteractionSP7 interactions

CUL1 HNF1B FOXP4 NFIA NFIC NFIX CHD7 NIPBL

1.61e-06304558int:SP7
InteractionZFHX4 interactions

FOXJ2 HNF1B FOXP4 FOXP2 NFIX

1.64e-0673555int:ZFHX4
InteractionCOIL interactions

CACTIN NFIA NFIC KLHL42 CHD7 HECTD1 NIPBL SNRNP200 TGS1 FOXP3

2.12e-065525510int:COIL
InteractionRFX1 interactions

FOXJ2 FOXP4 FOXP2 NFIC NFIX

2.75e-0681555int:RFX1
InteractionYY1 interactions

FOXJ2 HNF1B FOXP4 FOXP2 NFIA NFIC NFIX CHD7 FOXP3

3.50e-06454559int:YY1
InteractionGSC interactions

FOXP4 FOXP2 NFIA NFIC WWP2

3.92e-0687555int:GSC
InteractionSOX6 interactions

HNF1B FOXP4 NFIA NFIC NFIX CHD7

4.30e-06157556int:SOX6
InteractionSOX10 interactions

HNF1B NFIA NFIC NFIX CHD7

5.16e-0692555int:SOX10
InteractionCRX interactions

HNF1B FOXP4 FOXP2 NFIA NFIC CHD7 NIPBL

5.64e-06254557int:CRX
InteractionLHX4 interactions

HNF1B FOXP4 NFIA NFIC NFIX CHD7

5.92e-06166556int:LHX4
InteractionFOXP1 interactions

HNF1B FOXP4 FOXP2 NFIA NFIC NFIX FOXP3

5.93e-06256557int:FOXP1
InteractionFOXP4 interactions

FOXP4 FOXP2 NFIA NFIC FOXP3

7.04e-0698555int:FOXP4
InteractionSIX4 interactions

HNF1B NFIA NFIC NFIX

7.44e-0646554int:SIX4
InteractionARID3B interactions

HNF1B NFIA NFIC NFIX HECTD1

1.41e-05113555int:ARID3B
InteractionBCL7C interactions

HNF1B NFIA NFIC NFIX FOXP3

1.54e-05115555int:BCL7C
InteractionCUX1 interactions

FOXJ2 CUL1 HNF1B NFIC NFIX SLC15A3

1.67e-05199556int:CUX1
InteractionFTSJ3 interactions

CUL1 NFIA WWP2 AATF APOBEC3C HECTD1 TGS1 FOXP3

1.78e-05422558int:FTSJ3
InteractionFEV interactions

FOXP4 FOXP2 NFIA NFIC CHD7 NIPBL

1.86e-05203556int:FEV
InteractionARID3A interactions

HNF1B NFIA NFIC NFIX SNRNP200

2.04e-05122555int:ARID3A
InteractionERG interactions

FOXP4 NFIA NFIC CHD7 NIPBL SNRNP200

3.16e-05223556int:ERG
InteractionSOX15 interactions

HNF1B FOXP4 NFIA NFIC NFIX

4.10e-05141555int:SOX15
InteractionNFIB interactions

HNF1B FOXP4 NFIA NFIC NFIX

4.24e-05142555int:NFIB
InteractionTRPS1 interactions

FOXJ2 HNF1B NFIA NFIC NFIX

4.39e-05143555int:TRPS1
InteractionZNF609 interactions

HNF1B NFIA NFIC NFIX FLCN

4.84e-05146555int:ZNF609
InteractionETV7 interactions

NFIA NFIC CHD7

5.37e-0527553int:ETV7
InteractionTFAP4 interactions

CUL1 NFIA NFIC NFIX SNRNP200

6.05e-05153555int:TFAP4
InteractionSLU7 interactions

FOXJ2 CACTIN HECTD1 SNRNP200 FOXP3

6.64e-05156555int:SLU7
InteractionTLE3 interactions

FOXJ2 CACTIN HNF1B NFIA NFIC NFIX NIPBL

6.99e-05376557int:TLE3
InteractionKDM2B interactions

CUL1 HNF1B NFIA NFIC NFIX

7.71e-05161555int:KDM2B
InteractionNR2C1 interactions

HNF1B NFIA NFIC NFIX

8.15e-0584554int:NR2C1
InteractionPRDM1 interactions

HNF1B NFIA NFIC NFIX

8.15e-0584554int:PRDM1
InteractionIRF4 interactions

FOXP4 NFIA CHD7 NIPBL

8.53e-0585554int:IRF4
InteractionCDC5L interactions

CUL1 CACTIN FOXP4 NUP155 FOXP2 WWP2 HECTD1 NIPBL SNRNP200 FOXP3

9.24e-058555510int:CDC5L
InteractionATXN1 interactions

HNF1B CLCN2 NUP155 NFIA NFIC NFIX FUT9 TAB1 MAGT1 PPP6R2 SNRNP200

9.60e-0510395511int:ATXN1
InteractionKMT2D interactions

HNF1B NUP155 NFIA NFIC NFIX

9.69e-05169555int:KMT2D
InteractionPRR12 interactions

HNF1B NFIA NFIC NFIX

9.77e-0588554int:PRR12
InteractionPWP2 interactions

CUL1 WWP2 AATF HECTD1 FOXP3

1.05e-04172555int:PWP2
InteractionTLX1 interactions

FOXP4 NFIA NFIC CHD7 NIPBL

1.14e-04175555int:TLX1
InteractionSMC3 interactions

FOXJ2 NFIX AATF HECTD1 NIPBL SNRNP200 FOXP3

1.16e-04408557int:SMC3
InteractionSOX13 interactions

HNF1B FOXP4 FOXP2

1.18e-0435553int:SOX13
InteractionARID1B interactions

HNF1B NFIA NFIC NFIX WWP2

1.20e-04177555int:ARID1B
InteractionZNF608 interactions

HNF1B NFIA NFIC NFIX

1.21e-0493554int:ZNF608
InteractionDNTTIP1 interactions

FOXJ2 HNF1B CLCN2 WWP2

1.31e-0495554int:DNTTIP1
InteractionSAP130 interactions

CUL1 HNF1B NFIC NFIX HECTD1

1.34e-04181555int:SAP130
InteractionLHX3 interactions

FOXP4 NFIA NFIC CHD7 NIPBL

1.48e-04185555int:LHX3
InteractionNFAT5 interactions

FOXP4 FOXP2 FOXP3

1.52e-0438553int:NFAT5
InteractionDDX17 interactions

CUL1 CACTIN TRPV1 WWP2 AATF HECTD1 NIPBL

1.52e-04426557int:DDX17
InteractionHIVEP1 interactions

CACNA1A HNF1B NFIA NFIC NFIX

1.52e-04186555int:HIVEP1
InteractionNFIA interactions

HNF1B FOXP4 NFIA NFIC NFIX

1.60e-04188555int:NFIA
InteractionQSER1 interactions

FOXJ2 HNF1B NFIA NFIX

1.60e-04100554int:QSER1
InteractionFOXL1 interactions

MRPS30 FOXP4 NFIA NFIC CHD7

1.94e-04196555int:FOXL1
InteractionBPTF interactions

HNF1B NFIX HECTD1 SNRNP200 FOXP3

1.98e-04197555int:BPTF
InteractionCOX10 interactions

MAGT1 COA8

2.03e-048552int:COX10
InteractionRGSL1 interactions

RGSL1 MAGT1

2.03e-048552int:RGSL1
InteractionGATA2 interactions

CUL1 NFIA NFIC CHD7 NIPBL

2.08e-04199555int:GATA2
InteractionARID4B interactions

HNF1B NFIA NFIC NFIX HECTD1

2.08e-04199555int:ARID4B
InteractionNSUN2 interactions

TTLL12 CUL1 NFIC WWP2 AATF HECTD1

2.42e-04323556int:NSUN2
InteractionTBXT interactions

NFIA NFIC CHD7 NIPBL

2.83e-04116554int:TBXT
InteractionSATB1 interactions

HNF1B FOXP4 FOXP2 FOXP3

2.83e-04116554int:SATB1
InteractionAR interactions

TTLL12 FOXP4 NFIA NFIC NFIX RNF213 AATF CHD7 NIPBL SNRNP200

3.10e-049925510int:AR
InteractionELK3 interactions

FOXP4 NFIA NFIC CHD7

3.23e-04120554int:ELK3
InteractionWIZ interactions

HNF1B NFIA NFIC NFIX FOXP3

3.31e-04220555int:WIZ
InteractionPOLR1G interactions

CUL1 CACTIN AATF CHD7 APOBEC3C HECTD1 NIPBL

3.52e-04489557int:POLR1G
InteractionDPF2 interactions

HNF1B NFIA NFIC NFIX WWP2 FOXP3

3.66e-04349556int:DPF2
InteractionPOLR1E interactions

CUL1 CACTIN AATF CHD7 APOBEC3C HECTD1

3.72e-04350556int:POLR1E
InteractionCIC interactions

HNF1B NUP155 NFIA NFIC NFIX CHD7 APOBEC3C SNRNP200

4.51e-04673558int:CIC
InteractionHNRNPK interactions

CUL1 NFIC NFIX WWP2 RNF213 APOBEC3C HECTD1 NIPBL SNRNP200

4.61e-04853559int:HNRNPK
InteractionPAX6 interactions

HNF1B NFIA NFIC NFIX CHD7 NIPBL

4.71e-04366556int:PAX6
InteractionDAO interactions

AOC1 KLHL42

4.74e-0412552int:DAO
InteractionTFDP1 interactions

FOXP4 FOXP2 NFIC NFIX

4.76e-04133554int:TFDP1
InteractionRBM28 interactions

CUL1 WWP2 AATF APOBEC3C HECTD1 FOXP3

4.85e-04368556int:RBM28
InteractionGTF3C1 interactions

FOXJ2 NFIX WWP2 HECTD1 FOXP3

5.01e-04241555int:GTF3C1
InteractionUACA interactions

HNF1B TRPV1 WWP2 RNF213

5.18e-04136554int:UACA
InteractionSRSF3 interactions

ADCY10 MRPS30 CUL1 CACTIN NFIA WWP2 AATF

5.20e-04522557int:SRSF3
InteractionHSP90AA1 interactions

CUL1 CACTIN TRPV1 FOXP2 NFIC WWP2 FLCN TAB1 NLRP4 NIPBL SNRNP200

5.22e-0412635511int:HSP90AA1
InteractionTUBB1 interactions

CUL1 GABRG2 TRPV1 MAGT1

5.33e-04137554int:TUBB1
InteractionTBL1X interactions

HNF1B NFIA NFIC NFIX

5.48e-04138554int:TBL1X
InteractionBNC2 interactions

FOXP4 FOXP2

5.60e-0413552int:BNC2
InteractionLDLRAD4 interactions

WWP2 FLCN MAGT1

5.61e-0459553int:LDLRAD4
InteractionNCBP2 interactions

CUL1 WWP2 AATF SNRNP200

5.94e-04141554int:NCBP2
InteractionRPL10 interactions

MRPS30 WWP2 FLCN AATF TAB1 APOBEC3C HECTD1 NIPBL

5.96e-04702558int:RPL10
InteractionHIC2 interactions

FOXJ2 FOXP4 FOXP2

6.19e-0461553int:HIC2
InteractionZNF536 interactions

FOXJ2 HNF1B NFIX

6.19e-0461553int:ZNF536
InteractionRBPJ interactions

CUL1 NFIA NFIC NFIX CHD7

6.36e-04254555int:RBPJ
Cytoband19p13.3

CACTIN NFIC NFIX TINCR

1.92e-0423755419p13.3
CytobandEnsembl 112 genes in cytogenetic band chr22q13

TTLL12 TAB1 APOBEC3C PPP6R2

6.70e-04330554chr22q13
CytobandEnsembl 112 genes in cytogenetic band chr19p13

CACNA1A CACTIN NFIC NFIX TINCR

2.65e-03797555chr19p13
Cytoband7q36.1

CUL1 AOC1

3.60e-03745527q36.1
Cytoband22q13.1

TAB1 APOBEC3C

4.72e-038555222q13.1
CytobandEnsembl 112 genes in cytogenetic band chr8q12

CHD7 TGS1

5.51e-0392552chr8q12
Cytoband17q12

HNF1B AATF

6.35e-039955217q12
GeneFamilyForkhead boxes

FOXJ2 FOXP4 FOXP2 FOXP3

2.63e-0643414508
GeneFamilyFibrinogen C domain containing

ANGPTL2 TNN

1.46e-0325412554
CoexpressionGSE3039_NKT_CELL_VS_B2_BCELL_DN

WWP2 AKR1B15 FLCN CHD7 MMP10 SLC15A3

3.89e-06200556M6436
CoexpressionBOYLAN_MULTIPLE_MYELOMA_D_UP

NFIX SLC15A3 COA8 TGS1

4.23e-0592554MM786
CoexpressionBOYLAN_MULTIPLE_MYELOMA_D_UP

NFIX SLC15A3 COA8 TGS1

4.23e-0592554M5863
CoexpressionGSE14026_TH1_VS_TH17_UP

SLC37A1 GABRG2 CACTIN TRPV1 CHD7

6.28e-05200555M3356
CoexpressionGSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN

ANGPTL2 NFIC CHD7 SLC43A3 HECTD1

6.28e-05200555M7026
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-OPC_related-Oligodendrocyte/OPC|2m / Sample Type, Dataset, Time_group, and Cell type.

ANGPTL2 NFIA NFIX KCNQ3 CHD7 TINCR

1.73e-072005563c9a2f02294a9fb892b89e856291bd6423ffa0a9
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-OPC_related|2m / Sample Type, Dataset, Time_group, and Cell type.

ANGPTL2 NFIA NFIX KCNQ3 CHD7 TINCR

1.73e-072005568e49e7e9b02d8411e4ffae1f5113a2c18f5bf179
ToppCelldroplet-Heart-nan-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANGPTL2 FOXP2 ABCA6 NFIA SLC43A3

4.03e-061935550ca0439dfdcb2361ca8d1015fb874a5b5c635d31
ToppCellfacs-GAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANGPTL2 NFIA NFIC NFIX SLC43A3

4.13e-061945559709dc95fb6982b6a0467b507845d5bc17252e3e
ToppCellfacs-GAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANGPTL2 NFIA NFIC NFIX SLC43A3

4.13e-0619455593b7a9065430740ec31fce4e8c14ffccb498591d
ToppCellfacs-Heart-RA-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANGPTL2 FOXP2 ABCA6 NFIA SLC43A3

4.13e-0619455548063c9fe3e12aeff0707acada1baa2f8621f093
ToppCellfacs-GAT-Fat-18m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANGPTL2 NFIA NFIC NFIX SLC43A3

4.13e-061945550d2e65b44e3f143971c2fd24c4552f042b049cfa
ToppCellfacs-Heart-RA-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANGPTL2 FOXP2 ABCA6 NFIA SLC43A3

4.13e-06194555c422aeddb4e949a22f731da675bdf91dee86ba61
ToppCellfacs-Heart-RA-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANGPTL2 FOXP2 ABCA6 NFIA SLC43A3

4.13e-061945554f31d2cf7eb37b45fefc4da5b41aac0bfdd847b3
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

CUL1 FOXP4 NFIA KCNQ3 CHD7

4.57e-061985556d12ecaa9532c134d9c4562534dcb59a6420b4d3
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like-IPs_and_early_cortical_neurons|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

CUL1 FOXP4 NFIA KCNQ3 CHD7

4.57e-061985557943e4f67c3d6efb5c8b00aa0ff3cfe7be10c48d
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Mup5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TRPV1 FOXP2 ABCA6 NFIA

1.85e-051275546df92f80b8922ca00eb383f79cd8dda4d602adfc
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rxfp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANGPTL2 FOXP2 ABCA6 NFIA

2.09e-0513155481efe8b0ca4377e557a42ddb12aecaf3f46b15bf
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TRPV1 FOXP2 ABCA6 NFIA

2.78e-051415545ef3166c5271aa90fd0633016edfe2c74b835319
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY10 GABRG2 RGSL1 FUT9

3.11e-0514555496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCelldroplet-Heart-nan-24m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXJ2 MRPS30 CACNA1A ANGPTL2

4.45e-051595547ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCell356C-Epithelial_cells-Epithelial-C_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

HNF1B RGSL1 FOXP2 NFIX

4.67e-0516155478cb72c462167021195917a06052bcdc367ad890
ToppCell356C-Epithelial_cells-Epithelial-C_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

HNF1B RGSL1 FOXP2 NFIX

4.67e-0516155406e7becfd11d6ef1a45a9cfdfcb40b812600038e
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASS4 OVGP1 TNN SLC15A3

5.02e-051645548e6dbddacd56a07769163813e3ebfad13302bb62
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

TTLL12 ABCA6 FLCN SLC43A3

5.64e-0516955484b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CACTIN CHD7 MMP10 TINCR

8.35e-05187554f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGSL1 ANGPTL2 FOXP2 NFIA

9.06e-051915549d3fa8d8138700640cc7927521c7635299df697d
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3_mon-IPC_like-IPCs|3_mon / Sample Type, Dataset, Time_group, and Cell type.

FOXP4 NFIA KCNQ3 CHD7

9.06e-05191554e4c1c533771b582e21683dbec6f93a558d865e00
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGSL1 ANGPTL2 FOXP2 NFIA

9.06e-05191554d04ed1e04b8cb904237d8e8388fe7740c724237b
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3_mon-IPC_like|3_mon / Sample Type, Dataset, Time_group, and Cell type.

FOXP4 NFIA KCNQ3 CHD7

9.06e-0519155448cffb55c71bb8b34e926fc461fcd345ce43ea00
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

FOXP4 NFIA KCNQ3 CHD7

9.43e-05193554f24bae40f5cbcfece04fbefe4e3de1b88ac90de4
ToppCellfacs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANGPTL2 NFIA NFIX SLC43A3

9.43e-05193554735a72fac16397edde95e8eefa6f83caeb5ee5df
ToppCelldroplet-Heart-nan-24m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXP2 ABCA6 NFIA SLC43A3

9.43e-05193554d08919db9601941569b9a143dad4d8e6f56a4389
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANGPTL2 NFIA NFIC NFIX

9.43e-05193554eff718664fe0aaf89050efd9cc7b6dfb1df46666
ToppCellfacs-MAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIA NFIC NFIX SLC43A3

9.43e-05193554733f557bdc80293b40ccdf560f1675793df932d6
ToppCellfacs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANGPTL2 NFIA NFIX SLC43A3

9.43e-05193554ff901d2f3d7a511639c1e3b76058896c0d8a8602
ToppCellfacs-MAT-Fat-24m-Mesenchymal|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIA NFIC NFIX SLC43A3

9.43e-05193554eb3c46b6fb06dc8708dc3032189b47ed93ee2357
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like-IPCs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

FOXP4 NFIA KCNQ3 CHD7

9.43e-051935542088f1d210c73f74685492c63065c62ac3f553e9
ToppCellfacs-MAT-Fat-24m-Mesenchymal-mesenchymal_progenitor|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFIA NFIC NFIX SLC43A3

9.43e-05193554b45cd02081f97904eaea2d013e1fa980505d060b
ToppCellfacs-MAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANGPTL2 NFIA NFIC SLC43A3

9.62e-05194554f906b090f67df4cfe3498cdbb52cc0efa08e06cc
ToppCellfacs-MAT-Fat-18m-Mesenchymal|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANGPTL2 NFIA NFIC SLC43A3

9.62e-05194554944cdb0403d80a10a2eea2a3516a9343dbccc32c
ToppCellfacs-MAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANGPTL2 NFIA NFIC SLC43A3

9.62e-0519455485081d255fcc1e9854c0073321dd9f0feaa48866
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-IPC_like|3_mon / Sample Type, Dataset, Time_group, and Cell type.

FOXP4 NFIA KCNQ3 CHD7

9.62e-051945543e90be6f5b1c5c83632e62941fb18d6a627ec1b5
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-IPC_like-IPCs/Immature_PNs|3_mon / Sample Type, Dataset, Time_group, and Cell type.

FOXP4 NFIA KCNQ3 CHD7

9.82e-051955545e36a881fe2646f5a95d07d7b9265e6ada38730c
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38|World / Primary Cells by Cluster

FOXP4 NFIC NFIX KCNQ3

1.00e-0419655438da0751941adca650fe9b383d9f343153978eb5
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn|World / Primary Cells by Cluster

FOXP4 NFIC NFIX KCNQ3

1.00e-04196554721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CASS4 RGSL1 OVGP1 NLRP4

1.02e-04197554b597c292fc1cb381a4325fed15a32966c38def28
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANGPTL2 FOXP2 NFIA NFIC

1.02e-041975549af431323da6d099459b7360af40e5df998cffbd
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANGPTL2 NFIC NFIX TNN

1.02e-041975543fe665c0277d091290b63f0dd24c0c6536a45309
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Polychromatic_Erythroblast|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

TTLL12 NFIA SLC43A3 TGS1

1.06e-04199554fa698f00d2dad74d28b4696c8c23dce70f123e52
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANGPTL2 NFIA NFIC NFIX

1.06e-0419955449690494270981eec5b5261c59e0545dff90cc21
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

FOXP4 NFIA CHD7 NLRP4

1.06e-041995548e72efcd421639ac36ed036ee13f13de070d361f
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANGPTL2 ABCA6 NFIA NFIC

1.06e-0419955436883044787a9fb79cf7e83a7da8e34eea83f2f1
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Neuron|3m / Sample Type, Dataset, Time_group, and Cell type.

FOXP4 NFIA KCNQ3 CHD7

1.08e-042005543d134ae3c48ff4d1849db4fbe44ff73fb6c8c779
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-OPC_related|6m / Sample Type, Dataset, Time_group, and Cell type.

CASS4 ANGPTL2 FOXP2 CHD7

1.08e-04200554ea1e3eeddbc398ac97863120f7aa3f17569ca12a
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANGPTL2 ABCA6 NFIA NFIC

1.08e-04200554d87ca8b0007b1743ae23ebd3c7e8aa7f53e39335
ToppCellBiopsy_Control_(H.)-Immune-cDCs|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

CASS4 AOC1 ABCA6 NLRP4

1.08e-04200554cc6ba99a877a13c63dc1d6f81538065a7f29b8f6
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-OPC_related-Oligodendrocyte/OPC|6m / Sample Type, Dataset, Time_group, and Cell type.

CASS4 ANGPTL2 FOXP2 CHD7

1.08e-042005544a57f2f2dc6e2402ac4772b5cd38e033a6f1adee
ToppCell5'-Adult-LargeIntestine-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANGPTL2 ABCA6 NFIA NFIC

1.08e-042005545a87bb8eb1c6bd2fbc357e1528e15ba1c0051438
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CUL1 RGSL1 FOXP3

2.88e-04104553b5ca6e589f414e549f4990fe334d4ee54829b298
DrugA-K-V

NFIA NFIC NFIX MMP10

1.90e-0637554CID011840919
Drug7-biopterin

NFIA NFIC NFIX

3.75e-0613553CID005488923
DrugRetrorsine [480-54-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A

CACTIN TRPV1 AOC1 ANGPTL2 KCNQ3 C2CD2L

7.69e-061965562784_UP
DrugNetilmicin sulfate [56931-57-2]; Up 200; 2.8uM; PC3; HT_HG-U133A

CACNA1A OVGP1 ANGPTL2 CLCN2 TAB1 SNRNP200

8.15e-061985567302_UP
Drug3-bp

NFIA NFIC NFIX

1.26e-0519553CID005326878
Drugnitrazine paper

AOC1 MMP10

1.72e-053552CID005473499
DrugNSC325316

NFIA NFIC NFIX

2.28e-0523553CID000331608
Drug4alpha-hydroxytetrahydrobiopterin

NFIA NFIC NFIX

2.95e-0525553CID000129803
Diseasespecific developmental disorder (implicated_via_orthology)

FOXP4 FOXP2 FOXP3

2.45e-084553DOID:0060038 (implicated_via_orthology)
DiseaseRENAL CELL CARCINOMA, NONPAPILLARY

HNF1B FLCN

7.12e-057552144700
DiseaseNonpapillary renal cell carcinoma

HNF1B FLCN

7.12e-057552cv:CN074294
DiseaseJuvenile Myoclonic Epilepsy

CLCN2 KCNQ3

9.48e-058552C0270853
Diseasemigraine (is_implicated_in)

CACNA1A TRPV1

1.22e-049552DOID:6364 (is_implicated_in)
Diseasechronic musculoskeletal pain

FOXP2 WWP2

2.22e-0412552EFO_0022195
DiseaseNeonatal diabetes mellitus

HNF1B FOXP3

9.96e-0425552C0158981
Diseaseage at first birth measurement

MRPS30 CACNA1A FOXP2

1.48e-03120553EFO_0009101

Protein segments in the cluster

PeptideGeneStartEntry
ILNYFRDAWNIFDFV

CACNA1A

1621

O00555
FVSRKWRFRDYLEAN

CASS4

461

Q9NQ75
TFYFQFKNLWEANDR

APOBEC3C

16

Q9NRW3
RKRRKNSGLWSFYFF

ABCA6

1121

Q8N139
SVNFFRNWETYKQGF

ANGPTL2

326

Q9UKU9
ARLQEWDNFYKFSNR

ADCY10

1431

Q96PN6
QTQYSWERQAAFRFK

AOC1

556

P19801
QFDWNQFRAFARLDK

CHD7

1991

Q9P2D1
FAYTWFNLQARKRKY

NFIA

26

Q12857
RKFFLFYRQQKWASG

IQCH

386

Q86VS3
LFFKDRYFWRRSHWN

MMP10

306

P09238
QTWRFYFRTLFQQHN

PAQR7

56

Q86WK9
FSYTWFNLQARKRKY

NFIX

26

Q14938
ANSWRYSSAFTNRIF

MAGT1

101

Q9H0U3
FFIKDSLARGFQRWY

FLCN

156

Q8NFG4
NEIYHWFTRMFAFFR

FOXP3

361

Q9BZS1
RFRTAFRMKAYAFWQ

KCNQ3

471

O43525
LYLSYFNWRKDFTVN

FUT9

311

Q9Y231
EGNFNWRFVFRFDYL

FER1L4

1546

A9Z1Z3
YSWFTRTFAYFRRNA

FOXP2

531

O15409
RTFAYFRRNAATWKN

FOXP2

536

O15409
FSRKFYIAQWFRDTT

NIPBL

1671

Q6KC79
WFTRMFAYFRRNTAT

FOXP4

496

Q8IVH2
FAYFRRNTATWKNAV

FOXP4

501

Q8IVH2
AWSDNKIFRDRFLYT

NLRP4

171

Q96MN2
INFQDLSWSFRNLYK

FOXJ2

246

Q9P0K8
LWRYYEKNRSFSNAA

NUP155

1081

O75694
IISFSRDQWYRAFIF

SLC37A1

11

P57057
KQWYDFDRSSFVFVR

HECTD1

1041

Q9ULT8
SLFAFKSFRENWQRA

C2CD2L

91

O14523
LKFYTQQWEDYRFSS

CUL1

116

Q13616
FFAQTWYDRRLKFNS

GABRG2

116

P18507
EFKSWLFKFYQARSQ

C7orf77

36

A4D0Y5
ANGIFQLWFHFKRYR

CACTIN

741

Q8WUQ7
QEKWAQRSFRYYLFS

PEX11B

116

O96011
GRDATRRFFNWFYWS

SLC15A3

191

Q8IY34
DLFFKYTWNNFLHFQ

PPP6R2

376

O75170
YDNAISFSYKAWFIR

OVGP1

331

Q12889
VYNWFANRRKEEAFR

HNF1B

296

P35680
NADRWYQYFTKTVFL

MRPS30

101

Q9NP92
DYWFLLFTTQNRFIS

RGSL1

491

A5PLK6
DSWLKFRSENNCFLY

TAB1

51

Q15750
ELRSFWSYAFSRRFA

SLC43A3

266

Q8NBI5
AFAYTWFNLQARKRK

NFIC

26

P08651
SFNRNWRAFDFKEFS

AKR1B15

291

C9JRZ8
FADFTVYRNRTLQKW

AATF

356

Q9NY61
RWNYIEGTKLFAAFF

CNDP1

486

Q96KN2
NRDWYKRNFAITFFM

COA8

171

Q96IL0
AVRNYWRGFFAATFS

CLCN2

271

P51788
SWSELRNFARFLNYQ

RNF213

2211

Q63HN8
YDRSFRWKYHQFRFL

WWP2

491

O00308
NTGQLDFFKRWRSYV

TNN

1116

Q9UQP3
KWDRFVKRIFYFNFL

TRPV1

426

Q8NER1
FVYDVFWLRFSNRAF

TTLL12

486

Q14166
SWKRAFYYNARRLDD

TINCR

51

A0A2R8Y7D0
FWLQRQLSRFYDDAI

SNRNP200

266

O75643
KYWAQRYRLFSRFDD

TGS1

646

Q96RS0
KYNIFSDSWEAFRRF

KLHL42

471

Q9P2K6