Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	hexokinase activity	HKDC1 GCK HK2	1.22e-07	5	47	3	GO:0004396
GeneOntologyMolecularFunction	fructokinase activity	HKDC1 GCK HK2	1.22e-07	5	47	3	GO:0008865
GeneOntologyMolecularFunction	glucokinase activity	HKDC1 GCK HK2	1.22e-07	5	47	3	GO:0004340
GeneOntologyMolecularFunction	D-glucose binding	HKDC1 GCK HK2	4.37e-06	14	47	3	GO:0005536
GeneOntologyMolecularFunction	carbohydrate kinase activity	HKDC1 GCK HK2	1.58e-05	21	47	3	GO:0019200
GeneOntologyMolecularFunction	zinc ion binding	MEP1B ZMAT3 TRIM2 KMT2B CPXM2 ADAMTS2 DTNA DTNB ZFP37	1.99e-04	891	47	9	GO:0008270
GeneOntologyMolecularFunction	transition metal ion binding	MEP1B ZMAT3 TRIM2 KMT2B APP CPXM2 ADAMTS2 DTNA DTNB ZFP37	3.70e-04	1189	47	10	GO:0046914
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL2A1 DPT VWF HMCN1	9.89e-04	188	47	4	GO:0005201
GeneOntologyMolecularFunction	microtubule plus-end binding	MAPRE1 MAPRE3	1.22e-03	22	47	2	GO:0051010
GeneOntologyMolecularFunction	monosaccharide binding	HKDC1 GCK HK2	1.45e-03	95	47	3	GO:0048029
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	RAP1GDS1 NET1 DIS3 CYTH3	2.11e-03	231	47	4	GO:0005085
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor binding	LRP2 APP	2.90e-03	34	47	2	GO:0050750
GeneOntologyMolecularFunction	cytoskeletal protein binding	MAPRE1 MAPRE3 ABLIM1 TRIM2 PLEKHH2 ABLIM3 USH2A TTLL6	3.80e-03	1099	47	8	GO:0008092
GeneOntologyMolecularFunction	lipoprotein particle receptor binding	LRP2 APP	3.80e-03	39	47	2	GO:0070325
GeneOntologyBiologicalProcess	positive regulation of microtubule plus-end binding	MAPRE1 MAPRE3	5.08e-06	2	47	2	GO:1903033
GeneOntologyBiologicalProcess	regulation of microtubule plus-end binding	MAPRE1 MAPRE3	5.08e-06	2	47	2	GO:1903031
GeneOntologyBiologicalProcess	carbohydrate phosphorylation	HKDC1 GCK HK2	2.46e-05	25	47	3	GO:0046835
GeneOntologyBiologicalProcess	positive regulation of microtubule binding	MAPRE1 MAPRE3	5.06e-05	5	47	2	GO:1904528
GeneOntologyBiologicalProcess	glucose 6-phosphate metabolic process	HKDC1 GCK HK2	5.25e-05	32	47	3	GO:0051156
GeneOntologyBiologicalProcess	glycolytic process	HKDC1 GCK HK2 APP	1.14e-04	110	47	4	GO:0006096
GeneOntologyBiologicalProcess	ADP catabolic process	HKDC1 GCK HK2 APP	1.31e-04	114	47	4	GO:0046032
GeneOntologyBiologicalProcess	protein localization to organelle	LRP2 FSIP2 MAPRE1 MAPRE3 XPA RAP1GDS1 HK2 APP ABLIM3 KNL1	1.42e-04	1091	47	10	GO:0033365
GeneOntologyBiologicalProcess	purine nucleoside diphosphate catabolic process	HKDC1 GCK HK2 APP	1.45e-04	117	47	4	GO:0009137
GeneOntologyBiologicalProcess	purine ribonucleoside diphosphate catabolic process	HKDC1 GCK HK2 APP	1.45e-04	117	47	4	GO:0009181
GeneOntologyBiologicalProcess	pyridine nucleotide catabolic process	HKDC1 GCK HK2 APP	1.55e-04	119	47	4	GO:0019364
GeneOntologyBiologicalProcess	ADP metabolic process	HKDC1 GCK HK2 APP	1.60e-04	120	47	4	GO:0046031
GeneOntologyBiologicalProcess	ribonucleoside diphosphate catabolic process	HKDC1 GCK HK2 APP	1.65e-04	121	47	4	GO:0009191
GeneOntologyBiologicalProcess	pyridine-containing compound catabolic process	HKDC1 GCK HK2 APP	1.76e-04	123	47	4	GO:0072526
GeneOntologyBiologicalProcess	regulation of microtubule binding	MAPRE1 MAPRE3	1.81e-04	9	47	2	GO:1904526
GeneOntologyBiologicalProcess	nucleoside diphosphate catabolic process	HKDC1 GCK HK2 APP	1.82e-04	124	47	4	GO:0009134
GeneOntologyBiologicalProcess	purine nucleoside diphosphate metabolic process	HKDC1 GCK HK2 APP	2.31e-04	132	47	4	GO:0009135
GeneOntologyBiologicalProcess	purine ribonucleoside diphosphate metabolic process	HKDC1 GCK HK2 APP	2.31e-04	132	47	4	GO:0009179
GeneOntologyBiologicalProcess	pyruvate metabolic process	HKDC1 GCK HK2 APP	3.05e-04	142	47	4	GO:0006090
GeneOntologyBiologicalProcess	ribonucleoside diphosphate metabolic process	HKDC1 GCK HK2 APP	3.13e-04	143	47	4	GO:0009185
GeneOntologyBiologicalProcess	nucleoside diphosphate metabolic process	HKDC1 GCK HK2 APP	3.66e-04	149	47	4	GO:0009132
GeneOntologyBiologicalProcess	embryonic skeletal joint morphogenesis	COL2A1 HOXD11	3.90e-04	13	47	2	GO:0060272
GeneOntologyBiologicalProcess	purine ribonucleotide catabolic process	HKDC1 GCK HK2 APP	5.89e-04	169	47	4	GO:0009154
GeneOntologyBiologicalProcess	fructose 6-phosphate metabolic process	GCK HK2	5.98e-04	16	47	2	GO:0006002
GeneOntologyBiologicalProcess	protein import	LRP2 APP	5.98e-04	16	47	2	GO:0017038
GeneOntologyBiologicalProcess	embryonic skeletal joint development	COL2A1 HOXD11	6.76e-04	17	47	2	GO:0072498
GeneOntologyBiologicalProcess	collagen fibril organization	COL2A1 DPT ADAMTS2	6.94e-04	76	47	3	GO:0030199
GeneOntologyBiologicalProcess	ribonucleotide catabolic process	HKDC1 GCK HK2 APP	7.16e-04	178	47	4	GO:0009261
GeneOntologyBiologicalProcess	purine nucleotide catabolic process	HKDC1 GCK HK2 APP	7.78e-04	182	47	4	GO:0006195
GeneOntologyBiologicalProcess	positive regulation of cell cycle checkpoint	TTI1 KNL1	8.48e-04	19	47	2	GO:1901978
GeneOntologyBiologicalProcess	purine-containing compound catabolic process	HKDC1 GCK HK2 APP	8.78e-04	188	47	4	GO:0072523
GeneOntologyBiologicalProcess	protein localization to microtubule	MAPRE1 MAPRE3	9.41e-04	20	47	2	GO:0035372
GeneOntologyBiologicalProcess	carbohydrate catabolic process	HKDC1 GCK HK2 APP	1.02e-03	196	47	4	GO:0016052
GeneOntologyBiologicalProcess	NADH regeneration	GCK HK2	1.04e-03	21	47	2	GO:0006735
GeneOntologyBiologicalProcess	canonical glycolysis	GCK HK2	1.04e-03	21	47	2	GO:0061621
GeneOntologyBiologicalProcess	glucose catabolic process to pyruvate	GCK HK2	1.04e-03	21	47	2	GO:0061718
GeneOntologyBiologicalProcess	nicotinamide nucleotide metabolic process	HKDC1 GCK HK2 APP	1.15e-03	202	47	4	GO:0046496
GeneOntologyBiologicalProcess	pyridine nucleotide metabolic process	HKDC1 GCK HK2 APP	1.15e-03	202	47	4	GO:0019362
GeneOntologyCellularComponent	mitotic spindle astral microtubule end	MAPRE1 MAPRE3	1.48e-05	3	47	2	GO:1905721
GeneOntologyCellularComponent	spindle midzone	MAPRE1 MAPRE3 APP	9.93e-05	40	47	3	GO:0051233
GeneOntologyCellularComponent	cell leading edge	ABLIM1 BMX PLEKHH2 APP ABLIM3 USH2A CYTH3	1.18e-04	500	47	7	GO:0031252
GeneOntologyCellularComponent	mitotic spindle astral microtubule	MAPRE1 MAPRE3	1.37e-04	8	47	2	GO:0061673
GeneOntologyCellularComponent	astral microtubule	MAPRE1 MAPRE3	2.69e-04	11	47	2	GO:0000235
GeneOntologyCellularComponent	aster	MAPRE1 MAPRE3	3.22e-04	12	47	2	GO:0005818
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL2A1 DPT VWF HMCN1 ADAMTS2 USH2A	1.15e-03	530	47	6	GO:0062023
GeneOntologyCellularComponent	cell cortex	MAPRE1 GCK CEP85 PLEKHH2 HMCN1	1.43e-03	371	47	5	GO:0005938
GeneOntologyCellularComponent	lamellipodium	ABLIM1 PLEKHH2 APP ABLIM3	1.76e-03	230	47	4	GO:0030027
GeneOntologyCellularComponent	microtubule plus-end	MAPRE1 MAPRE3	1.80e-03	28	47	2	GO:0035371
Domain	Hexokinase_C	HKDC1 GCK HK2	1.39e-07	5	46	3	IPR022673
Domain	Hexokinase_N	HKDC1 GCK HK2	1.39e-07	5	46	3	IPR022672
Domain	Hexokinase_1	HKDC1 GCK HK2	1.39e-07	5	46	3	PF00349
Domain	Hexokinase_2	HKDC1 GCK HK2	1.39e-07	5	46	3	PF03727
Domain	HEXOKINASE_2	HKDC1 GCK HK2	1.39e-07	5	46	3	PS51748
Domain	Hexokinase_BS	HKDC1 GCK HK2	1.39e-07	5	46	3	IPR019807
Domain	HEXOKINASE_1	HKDC1 GCK HK2	1.39e-07	5	46	3	PS00378
Domain	Hexokinase	HKDC1 GCK HK2	2.78e-07	6	46	3	IPR001312
Domain	Distrobrevin	DTNA DTNB	5.93e-06	2	46	2	IPR017432
Domain	EB1_C	MAPRE1 MAPRE3	1.78e-05	3	46	2	IPR004953
Domain	EB1_C	MAPRE1 MAPRE3	1.78e-05	3	46	2	PS51230
Domain	MAPRE	MAPRE1 MAPRE3	1.78e-05	3	46	2	IPR027328
Domain	EB1	MAPRE1 MAPRE3	1.78e-05	3	46	2	PF03271
Domain	EGF	MEP1B LRP2 SCUBE3 PCSK5 NTNG1 HMCN1	2.29e-05	235	46	6	SM00181
Domain	EGF-like_dom	MEP1B LRP2 SCUBE3 PCSK5 NTNG1 HMCN1	3.17e-05	249	46	6	IPR000742
Domain	cEGF	LRP2 SCUBE3 HMCN1	3.49e-05	26	46	3	IPR026823
Domain	cEGF	LRP2 SCUBE3 HMCN1	3.49e-05	26	46	3	PF12662
Domain	AbLIM_anchor	ABLIM1 ABLIM3	3.55e-05	4	46	2	PF16182
Domain	AbLIM_anchor	ABLIM1 ABLIM3	3.55e-05	4	46	2	IPR032402
Domain	EGF_1	MEP1B LRP2 SCUBE3 NTNG1 HMCN1 USH2A	3.62e-05	255	46	6	PS00022
Domain	VWFA	PSMD4 VWF HMCN1 ITGAE	4.89e-05	82	46	4	PS50234
Domain	VWA	PSMD4 VWF HMCN1 ITGAE	5.38e-05	84	46	4	SM00327
Domain	Galactose-bd-like	MEP1B PCSK5 NTNG1 CPXM2	8.35e-05	94	46	4	IPR008979
Domain	EF-hand_dom_typ1	DTNA DTNB	8.85e-05	6	46	2	IPR015153
Domain	EF-hand_dom_typ2	DTNA DTNB	8.85e-05	6	46	2	IPR015154
Domain	EF-hand_2	DTNA DTNB	8.85e-05	6	46	2	PF09068
Domain	EF-hand_3	DTNA DTNB	8.85e-05	6	46	2	PF09069
Domain	VWF_A	PSMD4 VWF HMCN1 ITGAE	1.02e-04	99	46	4	IPR002035
Domain	HP	ABLIM1 ABLIM3	1.65e-04	8	46	2	PS51089
Domain	-	ABLIM1 ABLIM3	1.65e-04	8	46	2	1.10.950.10
Domain	VHP	ABLIM1 ABLIM3	1.65e-04	8	46	2	PF02209
Domain	Villin_headpiece	ABLIM1 ABLIM3	1.65e-04	8	46	2	IPR003128
Domain	VHP	ABLIM1 ABLIM3	1.65e-04	8	46	2	SM00153
Domain	EGF	MEP1B LRP2 SCUBE3 HMCN1	2.59e-04	126	46	4	PF00008
Domain	EGF_3	MEP1B LRP2 SCUBE3 NTNG1 HMCN1	2.72e-04	235	46	5	PS50026
Domain	EGF-like_CS	MEP1B LRP2 SCUBE3 NTNG1 HMCN1	4.40e-04	261	46	5	IPR013032
Domain	EGF_2	MEP1B LRP2 SCUBE3 NTNG1 HMCN1	4.72e-04	265	46	5	PS01186
Domain	TIL_dom	LRP2 VWF	5.30e-04	14	46	2	IPR002919
Domain	Growth_fac_rcpt_	LRP2 SCUBE3 PCSK5 HMCN1	5.82e-04	156	46	4	IPR009030
Domain	Laminin_N	NTNG1 USH2A	6.97e-04	16	46	2	IPR008211
Domain	LAMININ_NTER	NTNG1 USH2A	6.97e-04	16	46	2	PS51117
Domain	Laminin_N	NTNG1 USH2A	6.97e-04	16	46	2	PF00055
Domain	LamNT	NTNG1 USH2A	6.97e-04	16	46	2	SM00136
Domain	-	PCSK5 NTNG1 CPXM2	7.71e-04	73	46	3	2.60.120.260
Domain	-	PSMD4 VWF HMCN1	8.02e-04	74	46	3	3.40.50.410
Domain	ZZ	DTNA DTNB	8.85e-04	18	46	2	PF00569
Domain	ZF_ZZ_2	DTNA DTNB	8.85e-04	18	46	2	PS50135
Domain	ZF_ZZ_1	DTNA DTNB	8.85e-04	18	46	2	PS01357
Domain	PLAC	PCSK5 ADAMTS2	9.88e-04	19	46	2	PS50900
Domain	Znf_ZZ	DTNA DTNB	9.88e-04	19	46	2	IPR000433
Domain	PLAC	PCSK5 ADAMTS2	9.88e-04	19	46	2	IPR010909
Domain	ZnF_ZZ	DTNA DTNB	9.88e-04	19	46	2	SM00291
Domain	EGF_CA	LRP2 SCUBE3 HMCN1	1.24e-03	86	46	3	PF07645
Domain	Ephrin_rec_like	SCUBE3 PCSK5	1.72e-03	25	46	2	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	SCUBE3 PCSK5	1.72e-03	25	46	2	IPR011641
Domain	EGF_Ca-bd_CS	LRP2 SCUBE3 HMCN1	1.75e-03	97	46	3	IPR018097
Domain	EGF_CA	LRP2 SCUBE3 HMCN1	1.86e-03	99	46	3	PS01187
Domain	ASX_HYDROXYL	LRP2 SCUBE3 HMCN1	1.91e-03	100	46	3	PS00010
Domain	VWC	COL2A1 VWF	2.15e-03	28	46	2	PF00093
Domain	EGF-type_Asp/Asn_hydroxyl_site	LRP2 SCUBE3 HMCN1	2.26e-03	106	46	3	IPR000152
Domain	PH	BMX PLEKHH2 NET1 CYTH3	2.40e-03	229	46	4	PF00169
Domain	EGF_LAM_2	NTNG1 USH2A	2.47e-03	30	46	2	PS50027
Domain	EGF_LAM_1	NTNG1 USH2A	2.47e-03	30	46	2	PS01248
Domain	Laminin_EGF	NTNG1 USH2A	3.35e-03	35	46	2	PF00053
Domain	EGF_Lam	NTNG1 USH2A	3.35e-03	35	46	2	SM00180
Domain	EGF_CA	LRP2 SCUBE3 HMCN1	3.36e-03	122	46	3	SM00179
Domain	EGF-like_Ca-bd_dom	LRP2 SCUBE3 HMCN1	3.52e-03	124	46	3	IPR001881
Domain	VWFC_1	COL2A1 VWF	3.54e-03	36	46	2	PS01208
Domain	VWC	COL2A1 VWF	3.94e-03	38	46	2	SM00214
Domain	VWFC_2	COL2A1 VWF	3.94e-03	38	46	2	PS50184
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL2A1 SCUBE3 VWF APP ITGAE ADAMTS2	3.10e-05	258	34	6	MM14572
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL2A1 SCUBE3 VWF APP ITGAE ADAMTS2	7.19e-05	300	34	6	M610
Pathway	KEGG_MEDICUS_PATHOGEN_SHIGELLA_FIMA_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS	HKDC1 HK2	8.42e-05	6	34	2	M47654
Pubmed	Proteomics identifies the developmental regulation of HKDC1 in liver of pigs and mice.	HKDC1 GCK HK2	2.76e-07	10	47	3	37545422
Pubmed	Phosphorylation of the amyloid precursor protein (APP) at Ser-675 promotes APP processing involving meprin β.	MEP1B APP	1.79e-06	2	47	2	31604820
Pubmed	A hexokinase isoenzyme switch in human liver cancer cells promotes lipogenesis and enhances innate immunity.	GCK HK2	1.79e-06	2	47	2	33594203
Pubmed	DNA repair-deficient Xpa and Xpa/p53+/- knock-out mice: nature of the models.	ZMAT3 XPA	1.79e-06	2	47	2	11695546
Pubmed	A comprehensive genetic linkage map of the human genome. NIH/CEPH Collaborative Mapping Group.	COL2A1 VWF	1.79e-06	2	47	2	1439770
Pubmed	Peptide aptamers define distinct EB1- and EB3-binding motifs and interfere with microtubule dynamics.	MAPRE1 MAPRE3	1.79e-06	2	47	2	24478452
Pubmed	The metalloprotease meprin β generates amino terminal-truncated amyloid β peptide species.	MEP1B APP	1.79e-06	2	47	2	22879596
Pubmed	Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules.	MAPRE1 MAPRE3	1.79e-06	2	47	2	18230754
Pubmed	Meprin β knockout reduces brain Aβ levels and rescues learning and memory impairments in the APP/lon mouse model for Alzheimer's disease.	MEP1B APP	1.79e-06	2	47	2	35235058
Pubmed	EB1 and EB3 regulate microtubule minus end organization and Golgi morphology.	MAPRE1 MAPRE3	1.79e-06	2	47	2	28814570
Pubmed	Mammalian end binding proteins control persistent microtubule growth.	MAPRE1 MAPRE3	1.79e-06	2	47	2	19255245
Pubmed	Muscular dystrophies and the dystrophin-glycoprotein complex.	DTNA DTNB	1.79e-06	2	47	2	9146999
Pubmed	Tau regulates the localization and function of End-binding proteins 1 and 3 in developing neuronal cells.	MAPRE1 MAPRE3	1.79e-06	2	47	2	25761518
Pubmed	Novel phenotypes identified by plasma biochemical screening in the mouse.	GCK KMT2B	1.79e-06	2	47	2	12420138
Pubmed	EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms.	MAPRE1 MAPRE3	1.79e-06	2	47	2	21768326
Pubmed	End binding proteins are obligatory dimers.	MAPRE1 MAPRE3	1.79e-06	2	47	2	24040250
Pubmed	Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brain.	DTNA DTNB	5.36e-06	3	47	2	11316798
Pubmed	Molecular insights into mammalian end-binding protein heterodimerization.	MAPRE1 MAPRE3	5.36e-06	3	47	2	20008324
Pubmed	Cerebellar synaptic defects and abnormal motor behavior in mice lacking alpha- and beta-dystrobrevin.	DTNA DTNB	5.36e-06	3	47	2	16540561
Pubmed	Molecular basis of dystrobrevin interaction with kinesin heavy chain: structural determinants of their binding.	DTNA DTNB	5.36e-06	3	47	2	16288919
Pubmed	EB3, a novel member of the EB1 family preferentially expressed in the central nervous system, binds to a CNS-specific APC homologue.	MAPRE1 MAPRE3	5.36e-06	3	47	2	10644998
Pubmed	beta-dystrobrevin, a member of the dystrophin-related protein family.	DTNA DTNB	5.36e-06	3	47	2	9419360
Pubmed	Mitochondrial control of microglial phagocytosis by the translocator protein and hexokinase 2 in Alzheimer's disease.	HK2 APP	5.36e-06	3	47	2	36787364
Pubmed	MAP1B regulates microtubule dynamics by sequestering EB1/3 in the cytosol of developing neuronal cells.	MAPRE1 MAPRE3	5.36e-06	3	47	2	23572079
Pubmed	MicroRNA-146a represses LRP2 translation and leads to cell apoptosis in Alzheimer's disease.	LRP2 APP	5.36e-06	3	47	2	27241555
Pubmed	Megalin interacts with APP and the intracellular adapter protein FE65 in neurons.	LRP2 APP	5.36e-06	3	47	2	20637285
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	LRP2 GPRASP1 PSMD4 ABLIM1 PLAUR RAP1GDS1 CEP85 VWF APP CYTH3	6.81e-06	1285	47	10	35914814
Pubmed	Heterochronically early decline of Hox expression prior to cartilage formation in the avian hindlimb zeugopod.	COL2A1 HOXD11	1.07e-05	4	47	2	22708793
Pubmed	Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin.	APP TTLL6	1.07e-05	4	47	2	24065130
Pubmed	DAMAGE, a novel alpha-dystrobrevin-associated MAGE protein in dystrophin complexes.	DTNA DTNB	1.07e-05	4	47	2	14623885
Pubmed	Biglycan regulates the expression and sarcolemmal localization of dystrobrevin, syntrophin, and nNOS.	DTNA DTNB	1.07e-05	4	47	2	16807372
Pubmed	Interaction of apolipoprotein J-amyloid beta-peptide complex with low density lipoprotein receptor-related protein-2/megalin. A mechanism to prevent pathological accumulation of amyloid beta-peptide.	LRP2 APP	1.07e-05	4	47	2	9228033
Pubmed	CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex.	MAPRE1 MAPRE3	1.78e-05	5	47	2	15631994
Pubmed	EB1 and EB3 control CLIP dissociation from the ends of growing microtubules.	MAPRE1 MAPRE3	1.78e-05	5	47	2	16148041
Pubmed	Glucose metabolism gene polymorphisms and clinical outcome in pancreatic cancer.	GCK HK2	1.78e-05	5	47	2	20845477
Pubmed	EB/RP gene family encodes tubulin binding proteins.	MAPRE1 MAPRE3	1.78e-05	5	47	2	10188731
Pubmed	Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity.	MAPRE1 MAPRE3	1.78e-05	5	47	2	19146815
Pubmed	The mouse Hoxd13(spdh) mutation, a polyalanine expansion similar to human type II synpolydactyly (SPD), disrupts the function but not the expression of other Hoxd genes.	COL2A1 HOXD11	1.78e-05	5	47	2	11543619
Pubmed	Characterization of functional domains of human EB1 family proteins.	MAPRE1 MAPRE3	1.78e-05	5	47	2	14514668
Pubmed	Myospryn is a novel binding partner for dysbindin in muscle.	DTNA DTNB	2.67e-05	6	47	2	14688250
Pubmed	Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin.	ABLIM1 ABLIM3	2.67e-05	6	47	2	17194709
Pubmed	Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein.	LRP2 APP	2.67e-05	6	47	2	9837937
Pubmed	Mitotic regulation of the stability of microtubule plus-end tracking protein EB3 by ubiquitin ligase SIAH-1 and Aurora mitotic kinases.	MAPRE1 MAPRE3	2.67e-05	6	47	2	19696028
Pubmed	Different dystrophin-like complexes are expressed in neurons and glia.	DTNA DTNB	2.67e-05	6	47	2	10545507
Pubmed	Regulation of procollagen amino-propeptide processing during mouse embryogenesis by specialization of homologous ADAMTS proteases: insights on collagen biosynthesis and dermatosparaxis.	COL2A1 ADAMTS2	2.67e-05	6	47	2	16556917
Pubmed	miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics.	ABLIM1 ABLIM3	3.74e-05	7	47	2	22684256
Pubmed	Hox genes regulate digit patterning by controlling the wavelength of a Turing-type mechanism.	COL2A1 HOXD11	3.74e-05	7	47	2	23239739
Pubmed	Reinvestigation of the dysbindin subunit of BLOC-1 (biogenesis of lysosome-related organelles complex-1) as a dystrobrevin-binding protein.	DTNA DTNB	3.74e-05	7	47	2	16448387
Pubmed	Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells.	DTNA DTNB	3.74e-05	7	47	2	10747910
Pubmed	MLC1 trafficking and membrane expression in astrocytes: role of caveolin-1 and phosphorylation.	DTNA DTNB	3.74e-05	7	47	2	19931615
Pubmed	Alpha-dystrobrevin-1 recruits alpha-catulin to the alpha1D-adrenergic receptor/dystrophin-associated protein complex signalosome.	DTNA DTNB	3.74e-05	7	47	2	21115837
Pubmed	Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver.	GCK HK2	3.74e-05	7	47	2	18165236
Pubmed	Similarities and differences in the regulation of HoxD genes during chick and mouse limb development.	COL2A1 HOXD11	4.98e-05	8	47	2	30475793
Pubmed	TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation.	MAPRE1 MAPRE3	4.98e-05	8	47	2	26323690
Pubmed	Hox11 genes establish synovial joint organization and phylogenetic characteristics in developing mouse zeugopod skeletal elements.	COL2A1 HOXD11	4.98e-05	8	47	2	20978074
Pubmed	Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival.	COL2A1 VWF	4.98e-05	8	47	2	11691837
Pubmed	Bone morphology is regulated modularly by global and regional genetic programs.	COL2A1 HOXD11	6.40e-05	9	47	2	31221640
Pubmed	iASPP-PP1 complex is required for cytokinetic abscission by controlling CEP55 dephosphorylation.	MAPRE1 MAPRE3	6.40e-05	9	47	2	29743530
Pubmed	MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progression.	MAPRE1 MAPRE3	6.40e-05	9	47	2	23509069
Pubmed	Multiple roles of Hoxa11 and Hoxd11 in the formation of the mammalian forelimb zeugopod.	COL2A1 HOXD11	6.40e-05	9	47	2	14668414
Pubmed	EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis.	MAPRE1 MAPRE3	7.99e-05	10	47	2	23001180
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	COL2A1 DPT VWF HMCN1	9.33e-05	175	47	4	28071719
Pubmed	Absence of alpha-syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophin.	DTNA DTNB	9.75e-05	11	47	2	10995443
Pubmed	gamma-Syntrophin scaffolding is spatially and functionally distinct from that of the alpha/beta syntrophins.	DTNA DTNB	9.75e-05	11	47	2	16857187
Pubmed	VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5.	PCSK5 HOXD11	1.17e-04	12	47	2	18519639
Pubmed	Hoxa11 and Hoxd11 regulate chondrocyte differentiation upstream of Runx2 and Shox2 in mice.	COL2A1 HOXD11	1.17e-04	12	47	2	22916278
Pubmed	A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa.	LRP2 NTNG1	1.38e-04	13	47	2	21079607
Pubmed	A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome.	ZDHHC14 NSUN5P2 HK2	1.83e-04	81	47	3	16110338
Pubmed	Conditional ablation of the heparan sulfate-synthesizing enzyme Ext1 leads to dysregulation of bone morphogenic protein signaling and severe skeletal defects.	COL2A1 HOXD11	1.86e-04	15	47	2	20404326
Pubmed	Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease.	MAPRE1 APP	1.86e-04	15	47	2	20205790
Pubmed	ERK1 and ERK2 regulate chondrocyte terminal differentiation during endochondral bone formation.	COL2A1 VWF	2.40e-04	17	47	2	25401279
Pubmed	The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements.	COL2A1 HOXD11	2.40e-04	17	47	2	11850178
Pubmed	Gli3 and Plzf cooperate in proximal limb patterning at early stages of limb development.	COL2A1 HOXD11	2.70e-04	18	47	2	16015334
Pubmed	Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4.	COL2A1 HOXD11	2.70e-04	18	47	2	19000668
Pubmed	Misexpression of Pknox2 in mouse limb bud mesenchyme perturbs zeugopod development and deltoid crest formation.	COL2A1 HOXD11	2.70e-04	18	47	2	23717575
Pubmed	Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.	ABLIM1 DTNA	3.01e-04	19	47	2	15024025
Pubmed	Shox2 regulates progression through chondrogenesis in the mouse proximal limb.	COL2A1 HOXD11	3.01e-04	19	47	2	23038774
Pubmed	Hnrnpk is essential for embryonic limb bud development as a transcription activator and a collaborator of insulator protein Ctcf.	COL2A1 HOXD11	3.01e-04	19	47	2	37608075
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	PCSK5 DPT VWF ADAMTS2	3.54e-04	248	47	4	24006456
Pubmed	SOX9 is dispensable for the initiation of epigenetic remodeling and the activation of marker genes at the onset of chondrogenesis.	COL2A1 ABLIM3	3.69e-04	21	47	2	30021842
Pubmed	Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene.	ABLIM1 BMX	4.06e-04	22	47	2	22305495
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	MAPRE1 PSMD4 ABLIM1 CEP85 KNL1	4.32e-04	472	47	5	38943005
Pubmed	p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage.	MAPRE1 PSMD4	4.84e-04	24	47	2	19650074
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	TTI1 PSMD4 CEP85 APP DTNA DTNB KNL1	4.88e-04	1049	47	7	27880917
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	PCSK5 GPRASP1 VWF	5.54e-04	118	47	3	21078624
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	LRP2 MAPRE1 XPA NET1 ABLIM3 DIS3 ZFP37	5.93e-04	1084	47	7	11544199
Pubmed	Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation.	COL2A1 HOXD11	6.14e-04	27	47	2	11566859
Pubmed	Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome.	DTNA DTNB	6.14e-04	27	47	2	18468998
Pubmed	A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies.	COL2A1 ZMAT3	6.14e-04	27	47	2	34242585
Pubmed	Hydroureternephrosis due to loss of Sox9-regulated smooth muscle cell differentiation of the ureteric mesenchyme.	COL2A1 DPT	6.61e-04	28	47	2	20881014
Pubmed	JAWS coordinates chondrogenesis and synovial joint positioning.	COL2A1 HOXD11	7.09e-04	29	47	2	18539921
Pubmed	Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function.	GCK HK2	7.59e-04	30	47	2	27133129
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	COL2A1 DPT VWF	8.18e-04	135	47	3	28675934
Pubmed	Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.	FSIP2 ABLIM1 RAP1GDS1 TRIM2 APP	9.19e-04	558	47	5	35063084
Pubmed	Early embryonic expression of murine coagulation system components.	PLAUR VWF	9.75e-04	34	47	2	11154109
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	COL2A1 DPT VWF	1.03e-03	146	47	3	27068509
Pubmed	Inflammation-like changes in the urothelium of Lifr-deficient mice and LIFR-haploinsufficient humans with urinary tract anomalies.	COL2A1 LRP2	1.03e-03	35	47	2	32179912
Pubmed	Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury.	GCK HK2	1.22e-03	38	47	2	20185832
Pubmed	Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter.	COL2A1 DPT	1.22e-03	38	47	2	22833126
Pubmed	Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.	LRP2 HOXD11	1.22e-03	38	47	2	27820600
Cytoband	Ensembl 112 genes in cytogenetic band chr20q11	CDK5RAP1 MAPRE1 TTI1	2.12e-03	248	47	3	chr20q11
Cytoband	Ensembl 112 genes in cytogenetic band chr18q12	MEP1B DTNA	5.14e-03	104	47	2	chr18q12
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	DTNA DTNB	5.46e-04	18	35	2	91
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	BMX PLEKHH2 NET1 CYTH3	6.50e-04	206	35	4	682
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	GPRASP1 RAP1GDS1	3.13e-03	43	35	2	409
GeneFamily	LIM domain containing	ABLIM1 ABLIM3	5.81e-03	59	35	2	1218
Coexpression	NABA_CORE_MATRISOME	COL2A1 NTNG1 CDCP2 DPT VWF HMCN1 USH2A	5.70e-07	275	47	7	M5884
Coexpression	NABA_ECM_GLYCOPROTEINS	NTNG1 CDCP2 DPT VWF HMCN1 USH2A	1.35e-06	196	47	6	M3008
Coexpression	NABA_MATRISOME	COL2A1 MEP1B SCUBE3 PCSK5 NTNG1 CDCP2 DPT VWF HMCN1 ADAMTS2 USH2A	1.50e-06	1026	47	11	M5889
Coexpression	GSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_DN	ZDHHC14 ZMAT3 ABLIM1 XPA ITGAE NET1	1.52e-06	200	47	6	M8656
Coexpression	NABA_CORE_MATRISOME	COL2A1 NTNG1 CDCP2 DPT VWF HMCN1	8.52e-06	270	47	6	MM17057
Coexpression	NABA_MATRISOME	COL2A1 MEP1B SCUBE3 PCSK5 NTNG1 CDCP2 DPT VWF HMCN1 ADAMTS2	9.59e-06	1008	47	10	MM17056
Coexpression	NABA_ECM_GLYCOPROTEINS	NTNG1 CDCP2 DPT VWF HMCN1	2.33e-05	191	47	5	MM17059
Coexpression	GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_UP	NSUN5P2 GPRASP1 ABLIM1 NET1 ZFP37	2.77e-05	198	47	5	M3108
Coexpression	NABA_BASEMENT_MEMBRANES	NTNG1 HMCN1 USH2A	5.10e-05	40	47	3	M5887
Coexpression	HALLMARK_APICAL_SURFACE	NTNG1 PLAUR APP	6.80e-05	44	47	3	M5916
Coexpression	PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP	COL2A1 PCSK5 PLEKHH2	1.48e-04	57	47	3	MM948
Coexpression	WIEDERSCHAIN_TARGETS_OF_BMI1_AND_PCGF2	PLAUR NET1 ABLIM3	1.48e-04	57	47	3	M2316
Coexpression	PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP	COL2A1 PCSK5 PLEKHH2	1.56e-04	58	47	3	M2452
Coexpression	CSR_EARLY_UP.V1_UP	MAPRE1 PLAUR NET1 DIS3	1.64e-04	153	47	4	M2656
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	PCSK5 NTNG1 PLEKHH2 HMCN1 NET1 HOXD11 ADAMTS2 DTNA ZFP37 KNL1	6.00e-06	793	46	10	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPT ABLIM1 HMCN1 NET1 ADAMTS2 CYTH3	4.87e-08	190	47	6	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	ZDHHC14 NTNG1 PLEKHH2 HMCN1 ABLIM3 ADAMTS2	5.35e-08	193	47	6	acad568621ed677031797b8c2e34dafea798d681
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ZDHHC14 NTNG1 PLEKHH2 HMCN1 ABLIM3 ADAMTS2	5.51e-08	194	47	6	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ZDHHC14 NTNG1 PLEKHH2 HMCN1 ABLIM3 ADAMTS2	5.51e-08	194	47	6	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NTNG1 PLEKHH2 HMCN1 ABLIM3 ADAMTS2 DTNA	6.60e-08	200	47	6	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 PLEKHH2 HMCN1 USH2A DTNA	7.26e-07	160	47	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP2 PLEKHH2 HMCN1 USH2A DTNA	7.26e-07	160	47	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTNG1 DPT PLEKHH2 ABLIM3 ADAMTS2	1.30e-06	180	47	5	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTNG1 DPT PLEKHH2 ABLIM3 ADAMTS2	1.30e-06	180	47	5	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZDHHC14 DPT PLEKHH2 HMCN1 DTNA	1.33e-06	181	47	5	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PCSK5 HMCN1 NET1 ADAMTS2 DTNA	1.48e-06	185	47	5	427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ABLIM1 BMX VWF HMCN1 CPXM2	1.48e-06	185	47	5	a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LRP2 PCSK5 HKDC1 ABLIM1 ABLIM3	1.57e-06	187	47	5	3ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	NTNG1 PLEKHH2 HMCN1 ADAMTS2 DTNA	1.57e-06	187	47	5	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D175\|Adult / Lineage, Cell type, age group and donor	NTNG1 PLEKHH2 HMCN1 ADAMTS2 DTNA	1.57e-06	187	47	5	e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABLIM1 BMX VWF HMCN1 CPXM2	1.65e-06	189	47	5	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ZDHHC14 NTNG1 PLEKHH2 HMCN1 ABLIM3	1.65e-06	189	47	5	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZDHHC14 ABLIM1 APP HMCN1 ABLIM3	1.69e-06	190	47	5	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 ABLIM1 BMX VWF HMCN1	1.69e-06	190	47	5	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LRP2 HKDC1 ABLIM1 ABLIM3 DTNA	1.74e-06	191	47	5	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LRP2 HKDC1 ABLIM1 ABLIM3 DTNA	1.74e-06	191	47	5	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 NTNG1 PLEKHH2 ABLIM3 DTNA	1.74e-06	191	47	5	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HKDC1 ABLIM1 TRIM2 PLEKHH2 APP	1.74e-06	191	47	5	9032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HKDC1 ABLIM1 TRIM2 PLEKHH2 APP	1.74e-06	191	47	5	5717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NTNG1 PLEKHH2 HMCN1 ADAMTS2 DTNA	1.74e-06	191	47	5	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NTNG1 PLEKHH2 HMCN1 ADAMTS2 DTNA	1.78e-06	192	47	5	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTNG1 DPT PLEKHH2 ADAMTS2 DTNA	1.78e-06	192	47	5	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NTNG1 PLEKHH2 HMCN1 ADAMTS2 DTNA	1.83e-06	193	47	5	9f69edc97b868d23998abc98928a2e89a885ef8a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HKDC1 ABLIM1 TRIM2 PLEKHH2 APP	1.83e-06	193	47	5	263d185af6ed80e639f864e4966268e0862c61dc
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NTNG1 PLEKHH2 HMCN1 ABLIM3 ADAMTS2	1.83e-06	193	47	5	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	COPD-Endothelial\|COPD / Disease state, Lineage and Cell class	ZDHHC14 ABLIM1 VWF APP ABLIM3	1.83e-06	193	47	5	093b28dcccb5841c995d0b33fae0efd6b88f97e0
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTNG1 PLEKHH2 ABLIM3 ADAMTS2 DTNA	1.83e-06	193	47	5	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HKDC1 ABLIM1 TRIM2 PLEKHH2 APP	1.83e-06	193	47	5	80e058c224749b5fe0ba3e944b48317c2371cb63
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HKDC1 ABLIM1 TRIM2 PLEKHH2 APP	1.83e-06	193	47	5	b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCell	21-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	NTNG1 DPT PLEKHH2 ABLIM3 ADAMTS2	1.87e-06	194	47	5	8fc98d2c9d94f3bc6292265e20ab71c4f1f37bb3
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NTNG1 PLEKHH2 HMCN1 ADAMTS2 DTNA	1.87e-06	194	47	5	71d3c7448b1734de54187f902f65649f9283bd4c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ABLIM1 VWF APP HMCN1 NET1	1.87e-06	194	47	5	ea5e1bc8d9e27cabfe1fb833ca47ec0893593b12
ToppCell	21-Trachea-Mesenchymal\|Trachea / Age, Tissue, Lineage and Cell class	NTNG1 DPT PLEKHH2 ABLIM3 ADAMTS2	1.87e-06	194	47	5	749dd8113ef260e00facac09de9861d61725124a
ToppCell	facs-Heart-LA-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 BMX VWF NET1 ABLIM3	1.87e-06	194	47	5	33cc4f1d716cb71d54cdedbe9bbdc0d7b17c4777
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ABLIM1 VWF APP HMCN1 NET1	1.87e-06	194	47	5	cceb7c88492bb6cd531e1c2651638da1ddf30931
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	NTNG1 PLEKHH2 HMCN1 ADAMTS2 DTNA	1.92e-06	195	47	5	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	NTNG1 PLEKHH2 HMCN1 ADAMTS2 DTNA	1.92e-06	195	47	5	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NTNG1 DPT PLEKHH2 HMCN1 ADAMTS2	1.97e-06	196	47	5	9737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell	5'-Adult-LymphNode-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BMX VWF APP CPXM2 ABLIM3	2.07e-06	198	47	5	d7e15e61b6018e4c36461c9471ee29601929925c
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	NTNG1 PLEKHH2 HMCN1 ADAMTS2 DTNA	2.07e-06	198	47	5	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	5'-Adult-Appendix-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BMX VWF APP CPXM2 ABLIM3	2.07e-06	198	47	5	90e85fe7a0ab376a41666dfff6c0e95b7f1c9475
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NTNG1 PLEKHH2 HMCN1 ABLIM3 ADAMTS2	2.07e-06	198	47	5	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NTNG1 DPT PLEKHH2 HMCN1 ADAMTS2	2.07e-06	198	47	5	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	proximal-mesenchymal-Alveolar_Fibroblast\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NTNG1 DPT PLEKHH2 HMCN1 ADAMTS2	2.12e-06	199	47	5	7f4840ae6a888380feca722543e5e52783f3e35d
ToppCell	proximal-3-mesenchymal-Alveolar_Fibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NTNG1 DPT PLEKHH2 HMCN1 ADAMTS2	2.12e-06	199	47	5	301d02bbb37e6f1d24b6e865bc3fe3e91260eb30
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	NTNG1 PLEKHH2 HMCN1 ABLIM3 ADAMTS2	2.12e-06	199	47	5	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	proximal-mesenchymal-Alveolar_Fibroblast-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NTNG1 DPT PLEKHH2 HMCN1 ADAMTS2	2.12e-06	199	47	5	9a16e519fb0651a7c4d8e05b931df4fb3b0eb3d1
ToppCell	human_hepatoblastoma-Tumor_cells-T9\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	MAPRE1 HK2 NET1 DTNA CYTH3	2.12e-06	199	47	5	e9c83555d2197b740797a9f33b64f8f7a7ba1ee2
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NTNG1 DPT PLEKHH2 HMCN1 ADAMTS2	2.12e-06	199	47	5	66a79732caf2f04c09b4d9832377aa01ca477677
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Vein\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ABLIM1 VWF APP HMCN1 NET1	2.12e-06	199	47	5	cfb624c7728046fc7f3ef071f57e4d7b013f3fef
ToppCell	343B-Fibroblasts-Fibroblast-G\|343B / Donor, Lineage, Cell class and subclass (all cells)	NTNG1 DPT PLEKHH2 HMCN1 ADAMTS2	2.12e-06	199	47	5	f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell	distal-mesenchymal-Alveolar_Fibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NTNG1 DPT PLEKHH2 HMCN1 ADAMTS2	2.12e-06	199	47	5	655d07cf9a2fd9b945a2ed4f824cba0297de72a8
ToppCell	343B-Fibroblasts-Fibroblast-G-\|343B / Donor, Lineage, Cell class and subclass (all cells)	NTNG1 DPT PLEKHH2 HMCN1 ADAMTS2	2.12e-06	199	47	5	9c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCell	medial-mesenchymal-Alveolar_Fibroblast\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NTNG1 DPT PLEKHH2 HMCN1 ADAMTS2	2.18e-06	200	47	5	c22cbfecee00183dd4be678f116ab9fd9ad0a4dd
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Vein\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ABLIM1 VWF APP HMCN1 NET1	2.18e-06	200	47	5	7eb366b2c5394af7c77650bde6261e7dac67154e
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	NTNG1 DPT PLEKHH2 HMCN1 ADAMTS2	2.18e-06	200	47	5	8c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCell	medial-2-mesenchymal-Alveolar_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NTNG1 DPT PLEKHH2 HMCN1 ADAMTS2	2.18e-06	200	47	5	cc6062dac07916c29091fc6bee2b864d29e6525b
ToppCell	medial-mesenchymal-Alveolar_Fibroblast-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NTNG1 DPT PLEKHH2 HMCN1 ADAMTS2	2.18e-06	200	47	5	5c0716bf375c8158f7dc2c82bf5eaf37af594dd0
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NTNG1 PLEKHH2 HMCN1 ADAMTS2 DTNA	2.18e-06	200	47	5	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ABLIM1 BMX VWF HMCN1 NET1	2.18e-06	200	47	5	061ba851f941c616ddb462512e826c412881c3ce
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTNG1 PLEKHH2 ABLIM3 ADAMTS2	9.23e-06	125	47	4	b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1\|E16.5-samps / Age Group, Lineage, Cell class and subclass	DPT HOXD11 ADAMTS2 DTNA	2.62e-05	163	47	4	f1ec2625b52664308968b01d8e0275e1e0751480
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|E18.5-samps / Age Group, Lineage, Cell class and subclass	DPT ABLIM3 ADAMTS2 DTNA	2.69e-05	164	47	4	519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRP2 HKDC1 BMX HK2	2.69e-05	164	47	4	382e42701779d12a7948690b3be72d06dd75c8b4
ToppCell	normal_Lung-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	CEP85 TRIM2 APP NET1	3.24e-05	172	47	4	0657c736f3c52d25cf7f652eac005ddcde9232ef
ToppCell	Endothelial-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	ZDHHC14 BMX APP CPXM2	3.24e-05	172	47	4	d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCell	E15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCSK5 ABLIM1 BMX VWF	3.31e-05	173	47	4	b0ff9808e38cb64a734ced498cd0546728746cd5
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NTNG1 BMX DTNA ZFP37	3.46e-05	175	47	4	bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MEP1B PCSK5 HKDC1 MAPRE3	3.54e-05	176	47	4	7622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	BMX VWF HMCN1 CPXM2	3.54e-05	176	47	4	52af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-Myeloid-Mast_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAPRE1 MAPRE3 PLAUR GCK	3.62e-05	177	47	4	0176ffa5e66fa684d0a8264af0db8f77fc391afd
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DPT GCK PLEKHH2 TTLL6	3.62e-05	177	47	4	ac90e4ce5be304a5a7473736397327010f2d1999
ToppCell	Endothelial\|World / shred by cell class for turbinate	MAPRE3 BMX VWF ABLIM3	3.78e-05	179	47	4	052b2681974be00efb8503fa4e2c85d91d5ebd06
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	BMX VWF HMCN1 CPXM2	3.78e-05	179	47	4	8c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PCSK5 ABLIM1 BMX VWF	3.78e-05	179	47	4	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CEP85 VWF CPXM2 KNL1	3.86e-05	180	47	4	40d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTNG1 DPT PLEKHH2 ABLIM3	3.95e-05	181	47	4	9e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMX VWF HMCN1 TTLL6	3.95e-05	181	47	4	cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NTNG1 PLEKHH2 HMCN1 ABLIM3	3.95e-05	181	47	4	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-chondrocyte\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL2A1 SCUBE3 PLEKHH2 HOXD11	4.03e-05	182	47	4	ed487f3a774812caa2903a646b60c86edcc1e65e
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABLIM1 BMX VWF ABLIM3	4.03e-05	182	47	4	840427d1c23d60482c943ff006b14007ed44d247
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 LRP2 HMCN1 USH2A	4.21e-05	184	47	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NTNG1 PLEKHH2 CPXM2 ADAMTS2	4.21e-05	184	47	4	658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 LRP2 HMCN1 USH2A	4.21e-05	184	47	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 LRP2 HMCN1 USH2A	4.21e-05	184	47	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L3-4_RORB_RPS3P6\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NTNG1 PLEKHH2 CPXM2 USH2A	4.30e-05	185	47	4	10da5c2a92bfb3248d3f6f94a0933996326cf590
ToppCell	droplet-Heart-nan-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 BMX VWF ABLIM3	4.30e-05	185	47	4	a32d5cb596ebac80eb1ac301055e65d420879ec8
ToppCell	Control-Endothelial-Endothelial-Artery\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 BMX VWF HMCN1	4.39e-05	186	47	4	2d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LRP2 HKDC1 ABLIM1 ABLIM3	4.39e-05	186	47	4	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	BMX VWF HMCN1 CPXM2	4.48e-05	187	47	4	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	LRP2 PCSK5 ABLIM3 DTNA	4.48e-05	187	47	4	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	DPT PLEKHH2 HMCN1 ADAMTS2	4.48e-05	187	47	4	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	E17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCSK5 BMX VWF HMCN1	4.58e-05	188	47	4	59f276e23c8380bae57d7ecca3a8b83df4bc150b
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	ABLIM1 TRIM2 HMCN1 CPXM2	4.58e-05	188	47	4	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPT PLEKHH2 CPXM2 ADAMTS2	4.67e-05	189	47	4	544d95df910f1b276995624509a7e41b219baca0
Drug	Vincamine [1617-90-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A	ABLIM1 PLAUR CEP85 TRIM2 APP DTNA	3.11e-06	197	47	6	3865_DN
Drug	rofecoxib; Down 200; 10uM; MCF7; HG-U133A	LRP2 MAPRE3 ABLIM1 PLAUR APP ADAMTS2	3.20e-06	198	47	6	251_DN
Drug	C11122	DPT DTNA DTNB	3.69e-06	15	47	3	CID000119498
Drug	bromoacetylcholamine	DTNA DTNB	4.17e-06	2	47	2	CID000192097
Drug	NSC 226836	GCK HK2 DTNB	9.17e-06	20	47	3	CID000012600
Drug	olesoxime	MAPRE1 MAPRE3	2.50e-05	4	47	2	ctd:C522838
Drug	2,3-anhydro-D-allose	GCK HK2	2.50e-05	4	47	2	CID000191595
Drug	lofenal	GCK HK2	2.50e-05	4	47	2	CID000159256
Drug	N-bromoacetylglucosamine	GCK HK2	2.50e-05	4	47	2	CID000152920
Drug	1,5-anhydroglucitol 6-phosphate	GCK HK2	2.50e-05	4	47	2	CID003081444
Drug	1-deoxy-D-manno-heptulose	GCK HK2	2.50e-05	4	47	2	CID000193198
Drug	AC1L5VHN	GCK HK2	2.50e-05	4	47	2	CID000235938
Drug	3-chloromethylthiochromone-1,1-dioxide	GCK HK2	4.15e-05	5	47	2	CID000100620
Drug	pyrimidin-4-one	DPT APP	4.15e-05	5	47	2	CID000020695
Drug	2-fluoro-2-deoxy-6-phosphogluconate	GCK HK2	4.15e-05	5	47	2	CID000127270
Drug	Alsterpaullone; Up 200; 10uM; PC3; HT_HG-U133A	COL2A1 ABLIM1 APP DTNA DIS3	4.21e-05	188	47	5	7056_UP
Drug	ikarugamycin; Up 200; 2uM; MCF7; HT_HG-U133A_EA	GPRASP1 PLAUR TRIM2 DTNA DIS3	4.21e-05	188	47	5	974_UP
Drug	3-OMG	GCK VWF HK2	4.31e-05	33	47	3	CID000097217
Drug	Hymecromone [90-33-5]; Down 200; 22.8uM; PC3; HT_HG-U133A	GPRASP1 RAP1GDS1 APP DIS3 DTNB	4.77e-05	193	47	5	4623_DN
Drug	Palmatine chloride [3486-67-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A	PLAUR CEP85 TRIM2 APP DTNA	5.01e-05	195	47	5	4957_DN
Drug	Propoxycaine hydrochloride [550-83-4]; Down 200; 12uM; MCF7; HT_HG-U133A	GPRASP1 PLAUR TRIM2 DTNA DIS3	5.01e-05	195	47	5	6803_DN
Drug	Amyleine hydrochloride [532-59-2]; Down 200; 14.8uM; HL60; HG-U133A	XPA CEP85 APP NET1 DTNA	5.26e-05	197	47	5	1991_DN
Drug	Chlorzoxazone [95-25-0]; Down 200; 23.6uM; MCF7; HT_HG-U133A	ABLIM1 PLAUR XPA TRIM2 DTNA	5.39e-05	198	47	5	7456_DN
Drug	Acetopromazine maleate salt [3598-37-6]; Up 200; 9uM; PC3; HT_HG-U133A	LRP2 HKDC1 MAPRE3 TRIM2 HOXD11	5.52e-05	199	47	5	4494_UP
Drug	Labetalol hydrochloride [32780-64-6]; Up 200; 11uM; MCF7; HT_HG-U133A	PCSK5 APP DTNA DTNB CYTH3	5.65e-05	200	47	5	3167_UP
Drug	1,4-butanedithiol	GCK DTNA	6.22e-05	6	47	2	CID000079148
Drug	8-thiocyano-ATP	GCK HK2	6.22e-05	6	47	2	CID000132196
Drug	DTNP	DTNA DTNB	6.22e-05	6	47	2	CID000016474
Drug	Benzene	ZDHHC14 PCSK5 ZMAT3 ABLIM1 PLAUR XPA VWF KMT2B APP	7.45e-05	892	47	9	ctd:D001554
Drug	glucose 6-arsenate	GCK HK2	8.70e-05	7	47	2	CID000128033
Drug	AC1L5A5F	GCK HK2	8.70e-05	7	47	2	CID000173497
Drug	AFDG	GCK HK2	1.16e-04	8	47	2	CID000164297
Drug	NSC73599	DPT DTNB	1.16e-04	8	47	2	CID000007549
Drug	tetrahydropyran-2-methanol	GCK HK2	1.16e-04	8	47	2	CID000007524
Drug	mitomycin C	COL2A1 ZMAT3 PSMD4 XPA APP	1.36e-04	241	47	5	CID000005746
Drug	2-nitroimidazole	COL2A1 USH2A DTNA DTNB	1.45e-04	129	47	4	CID000010701
Drug	ethyl chloride	ITGAE ADAMTS2 DTNB	1.60e-04	51	47	3	CID000006337
Drug	3-bromopyruvate	GCK HK2 DTNB	1.70e-04	52	47	3	CID000070684
Drug	AC1O5VRZ	LRP2 APP	1.86e-04	10	47	2	CID006441686
Drug	ATP-EDC	GCK HK2	1.86e-04	10	47	2	CID000195647
Drug	Urokinase	LRP2 PLAUR	1.86e-04	10	47	2	DB00013
Drug	benzyl thiocyanate	COL2A1 GCK	1.86e-04	10	47	2	CID000018170
Drug	Creatine	COL2A1 APP	1.86e-04	10	47	2	ctd:D003401
Drug	Mitomycin	ZDHHC14 MAPRE1 ABLIM1 XPA TRIM2 APP	1.89e-04	410	47	6	ctd:D016685
Disease	hyperinsulinemic hypoglycemia (implicated_via_orthology)	HKDC1 GCK HK2	3.54e-08	5	46	3	DOID:13317 (implicated_via_orthology)
Disease	maturity-onset diabetes of the young (implicated_via_orthology)	HKDC1 GCK HK2	4.22e-07	10	46	3	DOID:0050524 (implicated_via_orthology)
Disease	hyperglycemia (implicated_via_orthology)	HKDC1 GCK HK2	2.37e-06	17	46	3	DOID:4195 (implicated_via_orthology)
Disease	glucose metabolism disease (implicated_via_orthology)	HKDC1 GCK HK2	1.13e-05	28	46	3	DOID:4194 (implicated_via_orthology)
Disease	Sensory hearing loss	COL2A1 LRP2	1.30e-04	11	46	2	C1691779
Disease	TNF-related apoptosis-inducing ligand measurement	MEP1B PLAUR DTNA	1.96e-04	72	46	3	EFO_0008300
Disease	Proteinuria	LRP2 VWF	2.46e-04	15	46	2	HP_0000093
Disease	Kidney Diseases	LRP2 PCSK5 HOXD11	3.55e-04	88	46	3	C0022658
Disease	unipolar depression, bipolar disorder, schizophrenia	PCSK5 ADAMTS2	4.44e-04	20	46	2	EFO_0003761, MONDO_0004985, MONDO_0005090
Disease	obesity (is_marker_for)	PLAUR VWF APP	5.31e-04	101	46	3	DOID:9970 (is_marker_for)
Disease	Sensorineural Hearing Loss (disorder)	COL2A1 LRP2	5.89e-04	23	46	2	C0018784
Disease	Bone Diseases, Developmental	PCSK5 HOXD11	8.14e-04	27	46	2	C0005941
Disease	glucose tolerance test	HKDC1 GCK	8.14e-04	27	46	2	EFO_0004307
Disease	immature platelet measurement	ZDHHC14 ZMAT3 VWF	8.55e-04	119	46	3	EFO_0803541
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	DTNA DTNB	1.45e-03	36	46	2	DOID:11723 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
CVRCHQMFTEGEEMY	ABLIM3	236	O94929
CSRCNQMFTEGEEMY	ABLIM1	311	O14639
FDTEEYCMAVCGSAM	APP	331	P05067
ECQEVYMAMRGNFSS	CDCP2	256	Q5VXM1
SQLLEMCYDVCEGMA	BMX	511	P51813
MCYDVCEGMAFLESH	BMX	516	P51813
FIMCRMTEYDCEFAN	DPT	186	Q07507
QCRFDFGLGYMMCTA	ADAMTS2	491	O95450
MKVFCNMETGETCVY	COL2A1	1311	P02458
KNCMVGYDMGATRCD	CPXM2	701	Q8N436
VGTGCNACYMEEMQN	GCK	226	P35557
ENAYRCGSGMQMAED	NET1	551	Q7Z628
KGGMDCECLQVDYMS	FSIP2	3806	Q5CZC0
GSNACYMEEMRNVEL	HK2	681	P52789
SNMMRNFYEKCFECN	ITGAE	226	P38570
MCQMGAICKDGEYVD	PCSK5	866	Q92824
VYSMCSLCQEENEDM	NSUN5P2	171	Q63ZY6
CKTVFYSSCNDAMEM	KNL1	451	Q8NG31
CTRCYEDNDYESKMM	KMT2B	1341	Q9UMN6
NMRGSFRCSCDTGYM	LRP2	1406	P98164
SEEGVQCSRMGSEMY	PLEKHH2	311	Q8IVE3
NRMCFNMRGSYQCID	HMCN1	5486	Q96RW7
TMSDRYAQDMGENCV	CEP85	746	Q6P2H3
TVFCGMLMNYSNEND	RAP1GDS1	156	P52306
MNDFDECGQSAASMY	HOXD11	1	P31277
DRMMEAFASRYCLCN	CYTH3	166	O43739
VECSYCRCESMMGFR	DTNB	241	O60941
EQLCSGAAYCQFMDM	MAPRE1	36	Q15691
EQLCSGAAYCQFMDM	MAPRE3	36	Q9UPY8
CHSESMMGFRYRCQQ	DTNA	246	Q9Y4J8
TMVCVDNSEYMRNGD	PSMD4	6	P55036
SCVNMMGSYECHCRE	SCUBE3	126	Q8IX30
FMDSCSFELENVCGM	MEP1B	261	Q16820
AMGNPYMCNNECDAS	NTNG1	81	Q9Y2I2
YMDCRAETSCDTMQG	GPRASP1	591	Q5JY77
MFCCGQDYVNMSDTI	USH2A	3321	O75445
GTGTNACYMEDMSNI	HKDC1	231	Q2TB90
RCMMQAVYFCSGMDN	DIS3	746	Q9Y2L1
FVSIMRGCDNMCSYC	CDK5RAP1	251	Q96SZ6
QSYMVRGCATASMCQ	PLAUR	256	Q03405
TCQNYDLECMSMGCV	VWF	791	P04275
SAMRDPCMQDQEAYS	TTLL6	816	Q8N841
MYGATQSQSDMCDQD	ZDHHC14	346	Q8IZN3
NLEDDMYRKTCTMCG	XPA	251	P23025
FYCSMCNVGAGEEME	ZMAT3	246	Q9HA38
MEFYCQSCETAMCRE	TRIM2	126	Q9C040
MLENYCNQASMGCQA	ZFP37	61	Q9Y6Q3
ATSTMMDVCRACGYD	TTI1	671	O43156