Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionacyltransferase activity

PORCN PNPLA3 DTX2 TRIM68 TRIM58 UBE2Z TRIM56

4.45e-05775267GO:0016746
GeneOntologyMolecularFunctionzinc ion binding

POLR1B DTX2 TRIM68 MORC2 TRIM58 NEIL1 TRIM56

1.07e-04891267GO:0008270
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

DTX2 TRIM68 TRIM58 UBE2Z TRIM56

3.18e-04473265GO:0004842
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

DTX2 TRIM68 TRIM58 UBE2Z TRIM56

4.58e-04512265GO:0019787
GeneOntologyMolecularFunctionaminoacyltransferase activity

DTX2 TRIM68 TRIM58 UBE2Z TRIM56

5.45e-04532265GO:0016755
GeneOntologyMolecularFunctiontransition metal ion binding

POLR1B DTX2 TRIM68 MORC2 TRIM58 NEIL1 TRIM56

6.30e-041189267GO:0046914
GeneOntologyMolecularFunctionubiquitin protein ligase activity

DTX2 TRIM68 TRIM58 TRIM56

1.28e-03372264GO:0061630
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

DTX2 TRIM68 TRIM58 TRIM56

1.64e-03398264GO:0061659
GeneOntologyMolecularFunctionO-acyltransferase activity

PORCN PNPLA3

2.67e-0359262GO:0008374
GeneOntologyBiologicalProcessregulation of viral process

SP100 TRIM68 MORC2 TRIM58 TRIM56

2.59e-06186255GO:0050792
GeneOntologyBiologicalProcessregulation of viral life cycle

TRIM68 MORC2 TRIM58 TRIM56

3.52e-05156254GO:1903900
GeneOntologyBiologicalProcessregulation of viral entry into host cell

TRIM68 TRIM58 TRIM56

3.96e-0555253GO:0046596
GeneOntologyBiologicalProcessmodulation by symbiont of entry into host

TRIM68 TRIM58 TRIM56

5.67e-0562253GO:0052372
GeneOntologyBiologicalProcessregulation of biological process involved in symbiotic interaction

TRIM68 TRIM58 TRIM56

1.00e-0475253GO:0043903
GeneOntologyBiologicalProcessviral process

SP100 TRIM68 MORC2 TRIM58 TRIM56

2.06e-04464255GO:0016032
GeneOntologyBiologicalProcessnegative regulation of viral process

SP100 MORC2 TRIM56

2.57e-04103253GO:0048525
GeneOntologyBiologicalProcessviral life cycle

TRIM68 MORC2 TRIM58 TRIM56

6.98e-04340254GO:0019058
GeneOntologyBiologicalProcesssymbiont entry into host cell

TRIM68 TRIM58 TRIM56

1.09e-03169253GO:0046718
GeneOntologyBiologicalProcesssymbiont entry into host

TRIM68 TRIM58 TRIM56

1.22e-03176253GO:0044409
DomainZnf_C3HC4_RING-type

DTX2 TRIM68 TRIM58 TRIM56

7.55e-05172254IPR018957
DomainBBOX

TRIM68 TRIM58 TRIM56

1.05e-0469253SM00336
Domainzf-B_box

TRIM68 TRIM58 TRIM56

1.19e-0472253PF00643
DomainZF_BBOX

TRIM68 TRIM58 TRIM56

1.63e-0480253PS50119
DomainZnf_B-box

TRIM68 TRIM58 TRIM56

1.69e-0481253IPR000315
Domainzf-C3HC4

DTX2 TRIM68 TRIM58 TRIM56

2.05e-04223254PF00097
DomainZF_RING_1

DTX2 TRIM68 TRIM58 TRIM56

5.64e-04291254PS00518
DomainZF_RING_2

DTX2 TRIM68 TRIM58 TRIM56

6.17e-04298254PS50089
DomainRING

DTX2 TRIM68 TRIM58 TRIM56

6.73e-04305254SM00184
DomainZnf_RING

DTX2 TRIM68 TRIM58 TRIM56

8.63e-04326254IPR001841
DomainZnf_RING_CS

TRIM68 TRIM58 TRIM56

1.30e-03163253IPR017907
DomainPRY

TRIM68 TRIM58

1.43e-0342252PF13765
DomainPRY

TRIM68 TRIM58

1.87e-0348252SM00589
DomainPRY

TRIM68 TRIM58

1.87e-0348252IPR006574
Domain-

DTX2 TRIM68 TRIM58 TRIM56

2.79e-034492543.30.40.10
DomainConA-like_dom

LAMA3 TRIM68 TRIM58

3.02e-03219253IPR013320
DomainZnf_RING/FYVE/PHD

DTX2 TRIM68 TRIM58 TRIM56

3.02e-03459254IPR013083
DomainButyrophylin

TRIM68 TRIM58

3.93e-0370252IPR003879
Domain-

TRIM68 TRIM58

4.04e-03712524.10.45.10
DomainSPRY

TRIM68 TRIM58

6.00e-0387252SM00449
DomainSPRY

TRIM68 TRIM58

6.97e-0394252PF00622
DomainSPRY_dom

TRIM68 TRIM58

6.97e-0394252IPR003877
DomainB30.2/SPRY

TRIM68 TRIM58

7.12e-0395252IPR001870
DomainB302_SPRY

TRIM68 TRIM58

7.12e-0395252PS50188
Pubmed

PML-like subnuclear bodies, containing XRCC1, juxtaposed to DNA replication-based single-strand breaks.

ORC5 SP100

1.22e-05727230260704
Pubmed

Odorant and vomeronasal receptor genes in two mouse genome assemblies.

OR4A8 OR4C11 OR11H4

2.61e-057427315081110
Pubmed

The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly.

CEP170 CEP76

9.84e-051927224421332
Pubmed

A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system.

TRIM68 UBE2Z TRIM56

1.05e-0411827319690564
Pubmed

Proteomic characterization of the human centrosome by protein correlation profiling.

CEP170 CEP76

1.86e-042627214654843
Pubmed

Interaction proteomics identify NEURL4 and the HECT E3 ligase HERC2 as novel modulators of centrosome architecture.

CEP170 CEP76

2.66e-043127222261722
Pubmed

The DNA sequence of human chromosome 7.

ORC5 MGAM DTX2 TRIM56

3.55e-0444127412853948
Pubmed

CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.

CEP170 MGAM TRIM56

3.76e-0418227331067453
Pubmed

Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons.

OR11H4 OR4N4C

5.88e-044627232126975
CytobandEnsembl 112 genes in cytogenetic band chr11q11

OR4A8 OR4C11

2.56e-0440272chr11q11
Cytoband1q44

CEP170 TRIM58

1.92e-031102721q44
Cytoband7q22.1

ORC5 TRIM56

2.02e-031132727q22.1
Cytoband7q34

MGAM DENND11

4.35e-031672727q34
Cytoband14q11.2

METTL17 OR11H4

5.03e-0318027214q11.2
CytobandEnsembl 112 genes in cytogenetic band chr7q34

MGAM DENND11

5.31e-03185272chr7q34
CytobandEnsembl 112 genes in cytogenetic band chr7q22

ORC5 TRIM56

7.35e-03219272chr7q22
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM68 TRIM58 TRIM56

1.08e-049518359
GeneFamilyRing finger proteins

DTX2 TRIM68 TRIM58 TRIM56

1.35e-0427518458
GeneFamilyOlfactory receptors, family 4

OR4A8 OR4C11

7.17e-03129182151
DrugdcaB

MGAM LPO

3.47e-063252CID000015340
Diseasesensory perception of bitter taste

MGAM DENND11

2.04e-0426242GO_0050913
Diseasemitochondrial heteroplasmy measurement

MGAM DENND11

1.44e-0369242EFO_0600008
DiseaseFatty Liver

PNPLA3 NEIL1

2.33e-0388242C0015695
DiseaseSteatohepatitis

PNPLA3 NEIL1

2.33e-0388242C2711227
Diseaseeosinophil measurement

METTL17 LPO

3.48e-03108242EFO_0803540
Diseaseobsolete_red blood cell distribution width

CEP170 PNPLA3 MFSD14B TRIM58 TRIM56

4.05e-031347245EFO_0005192
Diseasebitter alcoholic beverage consumption measurement

ORC5 MGAM

5.22e-03133242EFO_0010092
Diseasebilirubin measurement

QRFP PNPLA3 MFSD14B

5.35e-03442243EFO_0004570
Diseasehemoglobin A1 measurement

MGAM MFSD14B TRIM58

8.36e-03520243EFO_0007629
Diseaseobesity (implicated_via_orthology)

PNPLA3 NEIL1

1.31e-02215242DOID:9970 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
LFPFCREPSYFEIPT

CEP170

231

Q5SW79
QPKPLYPYRTIGCVF

CEP76

446

Q8TAP6
FGPAIFIYICPFRAL

OR4N4C

251

A0A096LPK9
YPIPIFYISQLPFCG

OR11H4

166

Q8NGC9
YYNFPFCLRIPIFPV

LAMA3

461

Q16787
FYTAPPGPRLALCFV

NEIL1

101

Q96FI4
KPFTARGFPRQCYLP

DTX2

526

Q86UW9
NPPFTPRILDGYLFC

MGAM

551

O43451
FPSAYFCLPRLPIGR

OPTC

316

Q9UBM4
PFFRAGFVCPTPPYK

LPO

276

P22079
CFIPFYSGLIPPSFR

PNPLA3

146

Q9NST1
ILFFGPCIFIYTRPP

OR4C11

246

Q6IEV9
RNCLRYFLPPSFPIS

MORC2

916

Q9Y6X9
PLIYFLFLPLGACFP

QRFP

6

P83859
LSTCVGPYLFPYFIP

PORCN

206

Q9H237
IFSPPPVGVVCYRVY

DENND11

261

A4D1U4
YIPGVFFRQFLPVSP

METTL17

241

Q9H7H0
PFLLGTVFFTCFPIP

MFSD14C

111

Q5VZR4
PFLLGTVFFTCFPIP

MFSD14B

111

Q5SR56
ILFFVPCIFLYVRPV

OR4A8

246

P0C604
PCIFLYVRPVSNFPI

OR4A8

251

P0C604
TYLERANCFPPPVFI

RHBDL2

61

Q9NX52
RPNTGCFEPFVLYFP

ORC5

166

O43913
PPVFGLYTSFFPVLI

SLC26A10

51

Q8NG04
IFTFPRYPFPGRLLP

TRIM68

446

Q6AZZ1
RPPLAFFLFCSEYRP

SP100

771

P23497
GFFLFVFRCPPDYPI

UBE2Z

146

Q9H832
LYPGLFLFTTPCRLV

POLR1B

606

Q9H9Y6
PYFFICDATPLILPP

TRIM58

446

Q8NG06
GLLPRPIFYCSFPTR

TRIM56

486

Q9BRZ2