Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmelatonin receptor activity

GPR50 MTNR1A MTNR1B

2.03e-074753GO:0008502
GeneOntologyMolecularFunctionoleoyl-CoA ligase activity

SLC27A1 SLC27A4

8.31e-054752GO:0090434
GeneOntologyMolecularFunctionoleate transmembrane transporter activity

SLC27A1 SLC27A4

2.07e-046752GO:1901480
GeneOntologyMolecularFunctionvery long-chain fatty acid-CoA ligase activity

SLC27A1 SLC27A4

6.14e-0410752GO:0031957
GeneOntologyMolecularFunctionarachidonate-CoA ligase activity

SLC27A1 SLC27A4

7.49e-0411752GO:0047676
GeneOntologyBiologicalProcessmedium-chain fatty acid transport

SLC27A1 SLC27A4

1.38e-052772GO:0001579
GeneOntologyBiologicalProcessregulation of extrinsic apoptotic signaling pathway via death domain receptors

FEM1B BRCA1 SKIL TMBIM1

4.58e-0553774GO:1902041
DomainMelatonin_rcpt

GPR50 MTNR1A MTNR1B

6.22e-083753IPR000025
DomainMel_1A_rcpt

MTNR1A MTNR1B

1.59e-052752IPR002278
Domain7TM_GPCR_Srsx

GPR50 MTNR1A MTNR1B CCR4 CHRM4

8.76e-05112755SM01381
DomainDUF1981

ARFGEF2 ARFGEF1

9.50e-054752PF09324
DomainSec7_N

ARFGEF2 ARFGEF1

9.50e-054752IPR032691
DomainSec7_N

ARFGEF2 ARFGEF1

9.50e-054752PF12783
DomainDCB_dom

ARFGEF2 ARFGEF1

9.50e-054752IPR032629
DomainDCB

ARFGEF2 ARFGEF1

9.50e-054752PF16213
DomainSec7_C

ARFGEF2 ARFGEF1

9.50e-054752IPR015403
DomainARM-like

IQCB1 ARFGEF2 ARFGEF1 XPO4 ATAD2 STAG3

7.55e-04270756IPR011989
DomainLipocalin_CS

APOD SLC27A4

1.02e-0312752IPR022272
Domain-

ARFGEF2 ARFGEF1

1.62e-03157521.10.1000.11
DomainSec7

ARFGEF2 ARFGEF1

1.62e-0315752PF01369
DomainSec7_alpha_orthog

ARFGEF2 ARFGEF1

1.62e-0315752IPR023394
DomainSec7

ARFGEF2 ARFGEF1

1.84e-0316752SM00222
DomainLaminin_N

LAMA3 USH2A

1.84e-0316752IPR008211
DomainSEC7

ARFGEF2 ARFGEF1

1.84e-0316752PS50190
DomainLAMININ_NTER

LAMA3 USH2A

1.84e-0316752PS51117
DomainSec7_dom

ARFGEF2 ARFGEF1

1.84e-0316752IPR000904
DomainLaminin_N

LAMA3 USH2A

1.84e-0316752PF00055
DomainLamNT

LAMA3 USH2A

1.84e-0316752SM00136
Domain-

ARFGEF2 ARFGEF1 XPO4 ATAD2 STAG3

1.99e-032227551.25.10.10
DomainAMP-bd_C

SLC27A1 SLC27A4

2.08e-0317752IPR025110
DomainAMP-binding_C

SLC27A1 SLC27A4

2.08e-0317752PF13193
DomainARM-type_fold

IQCB1 ARFGEF2 ARFGEF1 XPO4 STAG3 RYR3

2.41e-03339756IPR016024
DomainZnf_FYVE_PHD

MTMR4 ING2 SHPRH KDM4B

2.90e-03147754IPR011011
DomainTUDOR

KDM4B ALG13

3.81e-0323752PS50304
DomainAMP-binding_CS

SLC27A1 SLC27A4

4.86e-0326752IPR020845
DomainPHD

ING2 SHPRH KDM4B

5.52e-0389753SM00249
DomainAMP_BINDING

SLC27A1 SLC27A4

5.62e-0328752PS00455
DomainZnf_PHD

ING2 SHPRH KDM4B

5.87e-0391753IPR001965
DomainAMP-binding

SLC27A1 SLC27A4

6.44e-0330752PF00501
DomainTudor

KDM4B ALG13

6.44e-0330752IPR002999
DomainAMP-dep_Synth/Lig

SLC27A1 SLC27A4

6.44e-0330752IPR000873
DomainEGF_LAM_2

LAMA3 USH2A

6.44e-0330752PS50027
DomainEGF_LAM_1

LAMA3 USH2A

6.44e-0330752PS01248
DomainZF_PHD_2

ING2 SHPRH KDM4B

6.61e-0395753PS50016
DomainZF_PHD_1

ING2 SHPRH KDM4B

6.80e-0396753PS01359
DomainSNF2_N

SHPRH ZRANB3

7.30e-0332752IPR000330
DomainSNF2_N

SHPRH ZRANB3

7.30e-0332752PF00176
DomainDeath

UNC5A DTHD1

7.75e-0333752PF00531
PathwayREACTOME_TRANSPORT_OF_FATTY_ACIDS

SLC27A1 APOD SLC27A4

1.05e-066543MM15470
PathwayREACTOME_TRANSPORT_OF_FATTY_ACIDS

SLC27A1 APOD SLC27A4

2.94e-068543M27727
PathwayWP_SMALL_LIGAND_GPCRS

GPR50 MTNR1A MTNR1B

4.93e-0519543M39728
Pubmed

Identification of pathway-biased and deleterious melatonin receptor mutants in autism spectrum disorders and in the general population.

GPR50 MTNR1A MTNR1B

1.09e-08378320657642
Pubmed

Changes in melatonin receptor expression in a murine model of glaucoma.

GPR50 MTNR1A MTNR1B

4.33e-08478332818016
Pubmed

Mutation screening of melatonin-related genes in patients with autism spectrum disorders.

GPR50 MTNR1A MTNR1B

1.08e-07578320377855
Pubmed

Functional activity of serotoninergic and melatoninergic systems expressed in the skin.

GPR50 MTNR1A MTNR1B

2.16e-07678312767050
Pubmed

The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization.

GPR50 MTNR1A MTNR1B

3.77e-07778316778767
Pubmed

Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand.

MTNR1A MTNR1B

4.97e-06278222171046
Pubmed

Human gastroenteropancreatic expression of melatonin and its receptors MT1 and MT2.

MTNR1A MTNR1B

4.97e-06278225822611
Pubmed

Melatonin transmits photoperiodic signals through the MT1 melatonin receptor.

MTNR1A MTNR1B

4.97e-06278219261884
Pubmed

Melatonin in the mammalian olfactory bulb.

MTNR1A MTNR1B

4.97e-06278224365461
Pubmed

Association between genetic variations in MTNR1A and MTNR1B genes and gestational diabetes mellitus in Han Chinese women.

MTNR1A MTNR1B

4.97e-06278224157813
Pubmed

MTNR1A and MTNR1B Gene Variants of the Melatonin Receptor and Arterial Stiffness in Persons without Arterial Hypertension.

MTNR1A MTNR1B

4.97e-06278236892670
Pubmed

Melatonin MT₁ and MT₂ receptors display different molecular pharmacologies only in the G-protein coupled state.

MTNR1A MTNR1B

4.97e-06278224117008
Pubmed

Heteromeric MT1/MT2 melatonin receptors modulate photoreceptor function.

MTNR1A MTNR1B

4.97e-06278224106342
Pubmed

BRCA1 accumulates in the nucleus in response to hypoxia and TRAIL and enhances TRAIL-induced apoptosis in breast cancer cells.

BRCA1 TNFSF10

4.97e-06278217803681
Pubmed

Cyclical regulation of GnRH gene expression in GT1-7 GnRH-secreting neurons by melatonin.

MTNR1A MTNR1B

4.97e-06278211606436
Pubmed

MT1 and MT2 melatonin receptors play opposite roles in brain cancer progression.

MTNR1A MTNR1B

4.97e-06278233392634
Pubmed

Hearing impairment caused by mutations in two different genes responsible for nonsyndromic and syndromic hearing loss within a single family.

GJB2 USH2A

4.97e-06278229151245
Pubmed

Nature's knockout: the Mel1b receptor is not necessary for reproductive and circadian responses to melatonin in Siberian hamsters.

MTNR1A MTNR1B

4.97e-0627828923472
Pubmed

MT(1) melatonin receptor overexpression enhances the growth suppressive effect of melatonin in human breast cancer cells.

MTNR1A MTNR1B

4.97e-06278212088876
Pubmed

Stimulatory effects of a melatonin receptor agonist, ramelteon, on BDNF in mouse cerebellar granule cells.

MTNR1A MTNR1B

4.97e-06278218501512
Pubmed

Melatonin pathway genes and breast cancer risk among Chinese women.

MTNR1A MTNR1B

4.97e-06278222138747
Pubmed

Arf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex.

ARFGEF2 ARFGEF1

4.97e-06278223918382
Pubmed

Activation of melatonin receptor 2 but not melatonin receptor 1 mediates melatonin-conferred cardioprotection against myocardial ischemia/reperfusion injury.

MTNR1A MTNR1B

4.97e-06278230903623
Pubmed

Removal of melatonin receptor type 1 induces insulin resistance in the mouse.

MTNR1A MTNR1B

4.97e-06278220168308
Pubmed

Targeted deletions of Mel1a and Mel1b melatonin receptors affect pCREB levels in lactotroph and pars intermedia cells of mice.

MTNR1A MTNR1B

4.97e-06278216959416
Pubmed

Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma.

ARFGEF2 ARFGEF1

4.97e-06278217360629
Pubmed

Melatonin MT1 and MT2 receptor expression in Parkinson's disease.

MTNR1A MTNR1B

4.97e-06278220110911
Pubmed

Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complex.

ARFGEF2 ARFGEF1

4.97e-06278210716990
Pubmed

Placental melatonin production and melatonin receptor expression are altered in preeclampsia: new insights into the role of this hormone in pregnancy.

MTNR1A MTNR1B

4.97e-06278222686298
Pubmed

Melatonin signaling in mouse cerebellar granule cells with variable native MT1 and MT2 melatonin receptors.

MTNR1A MTNR1B

4.97e-06278218621029
Pubmed

Nociceptive responses in melatonin MT2 receptor knockout mice compared to MT1 and double MT1 /MT2 receptor knockout mice.

MTNR1A MTNR1B

4.97e-06278232430930
Pubmed

Membrane association of the Arabidopsis ARF exchange factor GNOM involves interaction of conserved domains.

ARFGEF2 ARFGEF1

4.97e-06278218203920
Pubmed

Major role of MT2 receptors in the beneficial effect of melatonin on long-term recognition memory in C57BL/6J male mice.

MTNR1A MTNR1B

4.97e-06278234634697
Pubmed

Localization of melatonin and its receptors (melatonin 1a and 1b receptors) in the mouse inner ear.

MTNR1A MTNR1B

4.97e-06278231561736
Pubmed

Melatonin inhibits embryonic salivary gland branching morphogenesis by regulating both epithelial cell adhesion and morphology.

MTNR1A MTNR1B

4.97e-06278225876057
Pubmed

Differential and day-time dependent expression of nuclear receptors RORα, RORβ, RORγ and RXRα in the rodent pancreas and islet.

MTNR1A MTNR1B

4.97e-06278223073388
Pubmed

Melatonin modulates visual function and cell viability in the mouse retina via the MT1 melatonin receptor.

MTNR1A MTNR1B

4.97e-06278219706469
Pubmed

Overexpressed FATP1, ACSVL4/FATP4 and ACSL1 increase the cellular fatty acid uptake of 3T3-L1 adipocytes but are localized on intracellular membranes.

SLC27A1 SLC27A4

4.97e-06278223024797
Pubmed

Impact of melatonin receptor deletion on intracellular signaling in spleen cells of mice after polymicrobial sepsis.

MTNR1A MTNR1B

4.97e-06278225352055
Pubmed

Family association study between melatonin receptor gene polymorphisms and polycystic ovary syndrome in Han Chinese.

MTNR1A MTNR1B

4.97e-06278226519818
Pubmed

Redundant roles of BIG2 and BIG1, guanine-nucleotide exchange factors for ADP-ribosylation factors in membrane traffic between the trans-Golgi network and endosomes.

ARFGEF2 ARFGEF1

4.97e-06278218417613
Pubmed

MTNR1A and MTNR1B gene polymorphisms in women with gestational diabetes.

MTNR1A MTNR1B

4.97e-06278228084098
Pubmed

Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer.

MTNR1A MTNR1B

4.97e-06278211940583
Pubmed

Genetic polymorphisms of melatonin receptors 1A and 1B may result in disordered lipid metabolism in obese patients with polycystic ovary syndrome.

MTNR1A MTNR1B

4.97e-06278230664204
Pubmed

Melatonin Signaling Controls the Daily Rhythm in Blood Glucose Levels Independent of Peripheral Clocks.

MTNR1A MTNR1B

4.97e-06278226824606
Pubmed

Evidence for feedback control of pineal melatonin secretion.

MTNR1A MTNR1B

4.97e-06278223528860
Pubmed

Positive relationship between melatonin receptor type 1B polymorphism and rheumatoid factor in rheumatoid arthritis patients in the Korean population.

MTNR1A MTNR1B

4.97e-06278216098099
Pubmed

Removal of melatonin receptor type 1 increases intraocular pressure and retinal ganglion cells death in the mouse.

MTNR1A MTNR1B

4.97e-06278221362461
Pubmed

Sleep-wake characterization of double MT₁/MT₂ receptor knockout mice and comparison with MT₁ and MT₂ receptor knockout mice.

MTNR1A MTNR1B

4.97e-06278223333399
Pubmed

Analysis of genetic variations in the human melatonin receptor (MTNR1A, MTNR1B) genes and antipsychotics-induced tardive dyskinesia in schizophrenia.

MTNR1A MTNR1B

4.97e-06278220726823
Pubmed

Genome-wide interaction with the insulin secretion locus MTNR1B reveals CMIP as a novel type 2 diabetes susceptibility gene in African Americans.

CMIP MTNR1B

4.97e-06278229691896
Pubmed

Food-induced reinforcement is abrogated by the genetic deletion of the MT1 or MT2 melatonin receptor in C3H/HeN mice.

MTNR1A MTNR1B

4.97e-06278229374562
Pubmed

Virtual discovery of melatonin receptor ligands to modulate circadian rhythms.

MTNR1A MTNR1B

4.97e-06278232040955
Pubmed

Description of the constitutive activity of cloned human melatonin receptors hMT(1) and hMT(2) and discovery of inverse agonists.

MTNR1A MTNR1B

4.97e-06278222017484
Pubmed

Preferential formation of MT1/MT2 melatonin receptor heterodimers with distinct ligand interaction properties compared with MT2 homodimers.

MTNR1A MTNR1B

4.97e-06278215266022
Pubmed

Melatonin receptor mRNA expression in human granulosa cells.

MTNR1A MTNR1B

4.97e-06278210612428
Pubmed

The hormone melatonin stimulates renoprotective effects of "early outgrowth" endothelial progenitor cells in acute ischemic kidney injury.

MTNR1A MTNR1B

4.97e-06278222357919
Pubmed

C-terminal domains within human MT1 and MT2 melatonin receptors are involved in internalization processes.

MTNR1A MTNR1B

4.97e-06278218341518
Pubmed

Cloning of a melatonin-related receptor from human pituitary.

GPR50 MTNR1B

4.97e-0627828647286
Pubmed

Melatonin 1A and 1B Receptors' Expression Decreases in the Placenta of Women with Fetal Growth Restriction.

MTNR1A MTNR1B

4.97e-06278232804352
Pubmed

Genetic deletion of MT(1) and MT(2) melatonin receptors differentially abrogates the development and expression of methamphetamine-induced locomotor sensitization during the day and the night in C3H/HeN mice.

MTNR1A MTNR1B

4.97e-06278222672659
Pubmed

Targeted disruption of the mouse Mel(1b) melatonin receptor.

MTNR1A MTNR1B

4.97e-06278212529409
Pubmed

Purification and cloning of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors.

ARFGEF2 ARFGEF1

4.97e-06278210212200
Pubmed

Gender-related invasion differences associated with mRNA expression levels of melatonin membrane receptors in colorectal cancer.

MTNR1A MTNR1B

4.97e-06278221809392
Pubmed

Genetic deletion of the MT1 or MT2 melatonin receptors abrogates methamphetamine-induced reward in C3H/HeN mice.

MTNR1A MTNR1B

4.97e-06278224813704
Pubmed

Melatonin signaling modulates clock genes expression in the mouse retina.

MTNR1A MTNR1B

4.97e-06278225203735
Pubmed

Genetic deletion of MT₁/MT₂ melatonin receptors enhances murine cognitive and motor performance.

MTNR1A MTNR1B

4.97e-06278225046530
Pubmed

Molecular pharmacology of the mouse melatonin receptors MT₁ and MT₂.

MTNR1A MTNR1B

4.97e-06278222202844
Pubmed

Melatonin in humans.

MTNR1A MTNR1B

4.97e-0627828988899
Pubmed

MT1 and MT2 melatonin receptors are expressed in nonoverlapping neuronal populations.

MTNR1A MTNR1B

4.97e-06278230937953
Pubmed

Melatonin receptors limit dopamine reuptake by regulating dopamine transporter cell-surface exposure.

MTNR1A MTNR1B

1.49e-05378230043140
Pubmed

Convergence of melatonin and serotonin (5-HT) signaling at MT2/5-HT2C receptor heteromers.

MTNR1A MTNR1B

1.49e-05378225770211
Pubmed

Interaction of phosphodiesterase 3A with brefeldin A-inhibited guanine nucleotide-exchange proteins BIG1 and BIG2 and effect on ARF1 activity.

ARFGEF2 ARFGEF1

1.49e-05378219332778
Pubmed

Specific functions of BIG1 and BIG2 in endomembrane organization.

ARFGEF2 ARFGEF1

1.49e-05378220360857
Pubmed

Fatty acid transporters in skin development, function and disease.

SLC27A1 SLC27A4

1.49e-05378224120574
Pubmed

AMY-1 (associate of Myc-1) localization to the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors.

ARFGEF2 ARFGEF1

1.49e-05378216866877
Pubmed

Functional domains of the fatty acid transport proteins: studies using protein chimeras.

SLC27A1 SLC27A4

1.49e-05378218258213
Pubmed

Expression of Melatonin and Dopamine D3 Receptor Heteromers in Eye Ciliary Body Epithelial Cells and Negative Correlation with Ocular Hypertension.

MTNR1A MTNR1B

1.49e-05378231936298
Pubmed

Melatonin receptor activation provides cerebral protection after traumatic brain injury by mitigating oxidative stress and inflammation via the Nrf2 signaling pathway.

MTNR1A MTNR1B

1.49e-05378230553970
Pubmed

Greb1 Transiently Accelerates Pancreatic β-Cell Proliferation in Diabetic Mice Exposed to Estradiol.

INS GREB1

1.49e-05378237516458
Pubmed

Evaluation of GPR50, hMel-1B, and ROR-alpha melatonin-related receptors and the etiology of adolescent idiopathic scoliosis.

GPR50 MTNR1B

1.49e-05378220733416
Pubmed

Melatonin exerts an inhibitory effect on insulin gene transcription via MTNR1B and the downstream Raf‑1/ERK signaling pathway.

INS MTNR1B

1.49e-05378229207116
Pubmed

Association of disease-predisposition polymorphisms of the melatonin receptors and sunshine duration in the global human populations.

GPR50 MTNR1B

1.49e-05378220050988
Pubmed

ING2 as a novel mediator of transforming growth factor-beta-dependent responses in epithelial cells.

ING2 SKIL

1.49e-05378218334480
Pubmed

Melatonin receptor depletion suppressed hCG-induced testosterone expression in mouse Leydig cells.

MTNR1A MTNR1B

1.49e-05378230915128
Pubmed

Involvement of BIG1 and BIG2 in regulating VEGF expression and angiogenesis.

ARFGEF2 ARFGEF1

1.49e-05378231199673
Pubmed

Enhancement of β-catenin activity by BIG1 plus BIG2 via Arf activation and cAMP signals.

ARFGEF2 ARFGEF1

1.49e-05378227162341
Pubmed

The Sec7 guanine nucleotide exchange factor GBF1 regulates membrane recruitment of BIG1 and BIG2 guanine nucleotide exchange factors to the trans-Golgi network (TGN).

ARFGEF2 ARFGEF1

1.49e-05378223386609
Pubmed

Regulation of bone mass through pineal-derived melatonin-MT2 receptor pathway.

MTNR1A MTNR1B

1.49e-05378228512916
Pubmed

Association of rotating night shift work, CLOCK, MTNR1A, MTNR1B genes polymorphisms and their interactions with type 2 diabetes among steelworkers: a case-control study.

MTNR1A MTNR1B

1.49e-05378237138267
Pubmed

The antidepressant-like effect of the melatonin receptor ligand luzindole in mice during forced swimming requires expression of MT2 but not MT1 melatonin receptors.

MTNR1A MTNR1B

1.49e-05378216098095
Pubmed

A C-terminal sequence in the guanine nucleotide exchange factor Sec7 mediates Golgi association and interaction with the Rsp5 ubiquitin ligase.

ARFGEF2 ARFGEF1

1.49e-05378218832381
Pubmed

FAT/CD36-mediated long-chain fatty acid uptake in adipocytes requires plasma membrane rafts.

SLC27A1 SLC27A4

1.49e-05378215496455
Pubmed

Molecular organization and dynamics of the melatonin MT₁ receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and G(i) coupling.

MTNR1A MTNR1B

1.49e-05378220859254
Pubmed

Comparative biochemical studies of the murine fatty acid transport proteins (FATP) expressed in yeast.

SLC27A1 SLC27A4

1.49e-05378215699031
Pubmed

Distinct functions for Arf guanine nucleotide exchange factors at the Golgi complex: GBF1 and BIGs are required for assembly and maintenance of the Golgi stack and trans-Golgi network, respectively.

ARFGEF2 ARFGEF1

1.49e-05378218003980
Pubmed

Rhythms in clock proteins in the mouse pars tuberalis depend on MT1 melatonin receptor signalling.

MTNR1A MTNR1B

1.49e-05378216324119
Pubmed

Human NB-2 of the contactin subgroup molecules: chromosomal localization of the gene (CNTN5) and distinct expression pattern from other subgroup members.

ARFGEF2 ARFGEF1

2.97e-05478211013081
Pubmed

Fatty acid transport protein expression in human brain and potential role in fatty acid transport across human brain microvessel endothelial cells.

SLC27A1 SLC27A4

2.97e-05478221395585
Pubmed

Interaction of FK506-binding protein 13 with brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1): effects of FK506.

ARFGEF2 ARFGEF1

2.97e-05478212606707
Cytoband3q26

TNFSF10 SKIL

5.95e-0577823q26
GeneFamilyMelatonin receptors

MTNR1A MTNR1B

9.42e-062562209
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_UP

LIG1 BRCA1 ATAD2 STAG3 ZRANB3 NUP205

8.68e-06163776M8235
CoexpressionDCA_UP.V1_DN

UPK1A LAMA3 MYL10 SKIL STAG3 ZNF248

1.78e-05185776M2760
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000

LIG1 BRCA1 IQCB1 ARFGEF2 XPO4 ATG14 TEX15 ATAD2 STAG3 KIF20B ZRANB3 NKRF NUP205 ALG13

8.00e-078227414gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_1000

BRCA1 IQCB1 XPO4 ATG14 TEX15 ATAD2 STAG3 KIF20B ZRANB3 NKRF NUP205 ALG13 TMEM63A

3.26e-067957413gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_1000
CoexpressionAtlasdev gonad_e11.5_F_PrimGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000

ARFGEF2 TEX15 ATAD2 STAG3 NKRF

3.15e-05104745gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_k2_1000
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500

BRCA1 IQCB1 ARFGEF2 TEX15 ATAD2 STAG3 NKRF ALG13

5.76e-05385748gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_500

BRCA1 IQCB1 ATG14 TEX15 ATAD2 STAG3 NKRF ALG13

8.35e-05406748gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_500
CoexpressionAtlasdev gonad_e11.5_F_PrimGermCell_Oct_top-relative-expression-ranked_1000

BRCA1 ARFGEF2 XPO4 ATG14 TEX15 ATAD2 STAG3 KIF20B ZRANB3 NKRF ALG13

9.60e-057997411gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_1000
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000

BRCA1 XPO4 ATG14 TEX15 ATAD2 STAG3 KIF20B ZRANB3 NKRF NUP205 ALG13

1.08e-048107411gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LIG1 BRCA1 LAMA3 TEX15 ATAD2

1.19e-051697850bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LIG1 BRCA1 LAMA3 TEX15 ATAD2

1.19e-05169785121768fc51fc3441ec725346a1bbe29e21d05971
ToppCelldroplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL21R MYL10 ATAD2 FDXACB1 TMEM18

1.26e-051717852e7cc311005958af52f39ca6c310c85b43a85aaf
ToppCelldroplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL21R MYL10 ATAD2 FDXACB1 TMEM18

1.26e-051717854b599f953c8e5b947b2c8bbbf7fe6f9dc388e336
ToppCelldroplet-Lung-21m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GJB2 BRCA1 CCR4 ARHGAP35 ATAD2

1.41e-051757856751ee4b312d7f87275f2c35e5878cfc3be3ebe3
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIG1 BRCA1 CCR4 TEX15 KIF20B

1.57e-0517978554621d2b3a66e62aa76b7e444118878ed97c1e02
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIG1 BRCA1 ATAD2 STAG3 KIF20B

1.70e-0518278511494a66d986297b837332ee9d382b71b9f22591
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LIG1 BRCA1 LAMA3 ATAD2 KIF20B

1.94e-051877859351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

LIG1 BRCA1 GREB1 ATAD2 KIF20B

2.68e-05200785691b3edf7d8449556e8bf611662eb85772959f0f
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

LIG1 BRCA1 GREB1 ATAD2 KIF20B

2.68e-0520078536a110aa91a791fdf1142e7869e8aa0d342402d0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells-Neuroepithelial_cell|GW08 / Sample Type, Dataset, Time_group, and Cell type.

LIG1 BRCA1 GREB1 ATAD2 KIF20B

2.68e-052007854e077aa7faddcebdfc54667f8b3990704441005b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

LIG1 BRCA1 GREB1 ATAD2 KIF20B

2.68e-05200785d17ba4239e1fd702a3d757687110f0f2c6f91ef7
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Hs3st6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TCAF2 THBD GJB2 APOD

6.49e-0512378464a2d7e40d9c948a9ccaf61c465fb2207e0b7ab8
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)|Striatum / BrainAtlas - Mouse McCarroll V32

NWD2 GPR68 PGAP6 ZNF248

7.57e-051287847e3f5cea91af005f08d8e9340fb8630bf1c887c3
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6|Striatum / BrainAtlas - Mouse McCarroll V32

NWD2 GPR68 PGAP6 ZNF248

7.57e-05128784a876303c852db2af9418d1a1711d7c950805018a
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)-|Striatum / BrainAtlas - Mouse McCarroll V32

NWD2 GPR68 PGAP6 ZNF248

7.57e-05128784388062f840fd04cb8087f27a9a78e7a192920e3e
ToppCellfacs-Pancreas-Exocrine-24m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NWD2 UPK1A SLC5A7 PKHD1L1

8.04e-051307848c81853c806e9a0d562e00dc5e00a8fc569a854c
ToppCelldroplet-Skin-nan-18m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD GJB2 APOD DTHD1

8.04e-051307844c8b931987432e8bcd39029d4fa124dc383ea355
ToppCellfacs-Pancreas-Exocrine-24m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NWD2 UPK1A SLC5A7 PKHD1L1

8.04e-051307843041d20fe964d282d95c0312396f26bc93929056
ToppCellfacs-Pancreas-Exocrine-24m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NWD2 UPK1A SLC5A7 PKHD1L1

8.04e-051307843b6a8eaef593db73c2fad2260b9f1e15950ccb70
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THBD COX6B1 RYR3 LRRC9

9.05e-05134784cb676d5bbc468bd3ce1b6712d41c986ee9221ac5
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-9|TCGA-Liver / Sample_Type by Project: Shred V9

FEM1B NWD2 TNFSF10 USH2A

1.33e-04148784683b2b80ee389469d948aaf6a77632b24f56e989
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

RINT1 XPO4 ZHX1 ZNF248

1.51e-04153784553dff9688a1996d8f4ba16e60c683593d781389
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

RINT1 XPO4 ZHX1 ZNF248

1.51e-0415378488ca2d2c2ab19fbee13e18951b993ee05dd30f67
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Efna5|Hippocampus / BrainAtlas - Mouse McCarroll V32

UPK1A SPATA9 STAG3

1.52e-045978352cf452beca2fc91f131997610228a1b04a7f5df
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Efna5-Inhibitory_Gad1Gad2_Htr3a.Efba5_(Interneuron,__(candidate_CGE-derived_4))|Hippocampus / BrainAtlas - Mouse McCarroll V32

UPK1A SPATA9 STAG3

1.52e-0459783e85f816cbebe7efe99d368cf5c01e68b39e231ac
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Efna5-Inhibitory_Gad1Gad2_Htr3a.Efba5_(Interneuron,__(candidate_CGE-derived_4))-|Hippocampus / BrainAtlas - Mouse McCarroll V32

UPK1A SPATA9 STAG3

1.52e-045978318cb0aaa7c0652721b4004a042cbc8ff4328a065
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LIG1 UPK1A APOD ZRANB3

1.75e-041597847ed659163f45e0c4df4782997c0786900c8186c8
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DTHD1 USH2A PKHD1L1 RYR3

1.79e-04160784c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DTHD1 USH2A PKHD1L1 RYR3

1.79e-0416078425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IQCB1 XPO4 KIF20B ZNF248

1.83e-04161784d72c572613f8eff3251cb7b1e9dcc76d193b2f21
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LIG1 GPR68 CCR4 CHRM4

1.97e-04164784e5258efd6765acfc394708f697ec76acaef09079
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LIG1 BRCA1 LAMA3 ATAD2

2.01e-0416578488681101d7cf60b99b8ace5d8c0944323b937306
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRCA1 SLC5A7 PGAP6 ALG13

2.01e-041657841703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCelldroplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD2 STAG3 KIF20B ZRANB3

2.01e-0416578496f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCelldroplet-Marrow-BM-30m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INS TEX15 PPP1R42 SLC27A4

2.06e-04166784019d365df44c3bbd88c1f4bdceb3de0ff76d3e8d
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC5A7 KRTAP24-1 TEX15 NKRF

2.06e-04166784548d0d6c0ffd564036ddba78620734220ebb73d7
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC5A7 KRTAP24-1 TEX15 NKRF

2.06e-0416678480e164a89d22098cabe4a99a78283ba69ea0561e
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GJB2 BRCA1 CCR4 ARHGAP35

2.06e-0416678421ba5fd755c0fb31ada42a1b5d60bede0153323d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL21R POGZ ZRANB3 NKRF

2.11e-041677843b717d33aaf1ef0869cc4bca8432ba8008875cc5
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LIG1 BRCA1 ATAD2 KIF20B

2.11e-0416778450c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LIG1 BRCA1 LAMA3 ATAD2

2.11e-04167784108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZDHHC21 ATG14 ATAD2 KIF20B

2.16e-041687844c402a1613fcf0a6e4d9b9d5551812940e91ff32
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BRCA1 GYG1 KIF20B LRRC9

2.21e-04169784563c267edaade0e5df192ad953801ef9768d4270
ToppCellwk_15-18-Hematologic-Meg-ery-Megakaryocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CMIP CCR4 PKHD1L1 TMBIM1

2.21e-04169784d571e84e01e3316748d4407ed98881b17484e035
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UPK1A USH2A PKHD1L1 RYR3

2.21e-0416978412bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellfacs|World / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD INS SKIL TMBIM1

2.31e-041717845bcb96ed7fc15548f2dc9cf47482f890640cb39c
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL21R CCR4 DTHD1 CHRM4

2.36e-041727844d04df9776394ea156ed5822f92ae74fdefbaa3d
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL21R CCR4 DTHD1 CHRM4

2.36e-041727843acf35b774ebc0f9e96299d0bd3e9d03bbf6b90c
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF1 TEX15 PPP1R42 SLC27A4

2.36e-04172784d354424c1f861b6607dfd63b9724f4c237b30275
ToppCellfacs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BRCA1 TMEM45B IL21R PGAP6

2.36e-0417278448d0cfc37d1b1ae48ed8f8b2711abeb609d2bb6e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TCAF2 IL21R ZRANB3 NUP205

2.41e-041737841bf9c91c1803a540b5e43bc4280aab4289341cee
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIG1 BRCA1 GPR68 ATAD2

2.41e-0417378420a20429aa898097d5ec4880ed64846558b5890f
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

BRCA1 ARHGAP35 ZRANB3 NKRF

2.41e-041737847e2149205e119cec4f5099c83c85d1e13470137a
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOD USH2A PKHD1L1 RYR3

2.41e-0417378466f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOD USH2A PKHD1L1 RYR3

2.41e-04173784649b08a409095592cccf31883be69c754411280d
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC27A1 GREB1 MYL10 CHRM4

2.52e-041757849a96794df049d8228fea57c1584c160191d36b56
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL21R CCR4 DTHD1 CHRM4

2.52e-041757843bdccb4037053795d62ab5b6fcc09cdd406f9b50
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-regulatory_T_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL21R CCR4 DTHD1 CHRM4

2.52e-04175784770546ddaa49ee482c4c7577ab76efbc6c304a29
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LIG1 BRCA1 UPK1A ATAD2

2.58e-041767849e719e6323597ecfc758c957256872cd4ae24d4d
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SHPRH XPO4 KIF20B NUP205

2.58e-0417678491ad2c34144f72283ca112fd3b3784f2f6259f65
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LIG1 THBD TNFSF10 ATAD2

2.63e-041777840e74980a7686c31fcf1476b8f19a3392541df240
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LIG1 TMEM45B TEX15 ATAD2

2.75e-04179784bf012825e88626e59cd1deebf67c2cd269ce4829
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LIG1 BRCA1 ATAD2 KIF20B

2.75e-0417978454191c00b29f53b520cd3243b5791daa4a2c72d7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LIG1 BRCA1 LAMA3 ATAD2

2.75e-0417978488d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellT_cells-GZMK+_CD8+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

GPR68 GYG1 ARHGAP35 DTHD1

2.75e-04179784798f208014f2229c597934775646ddbbacf94b69
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ARFGEF2 ARFGEF1 ARHGAP35 PPP1R42

2.81e-0418078462511d76d24b836839c3dcc2bf30485ffe9401e2
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR68 IQCB1 KIF20B ZRANB3

2.81e-0418078487347af8f28cf7c486c19f3f98c0afb022c323b5
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CMIP GPR68 GYG1 DTHD1

2.81e-04180784f24d4cbba4cb50fce3b3d9c4629aa856d9b05358
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LIG1 BRCA1 ATAD2 KIF20B

2.81e-04180784f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCellfacs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBD POGZ NKRF KDM4B

2.81e-041807847368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GPR68 XPO4 KIF20B NKRF

2.87e-04181784986c036e656f24fe374807e2711cec9e3c83c892
ToppCellfacs-Heart-RA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC5A TMEM45B UPK1A FDXACB1

2.87e-04181784c68d272eb41f81bd8ea4d0360733a2396bc87037
ToppCellfacs-Heart-RA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC5A TMEM45B UPK1A FDXACB1

2.87e-041817845e5eb89f224ee48065a328ade030cbc4dcdcac12
ToppCellMesenchymal_cells-Stromal_fibro.|Mesenchymal_cells / Lineage and Cell class

GJB2 SLC27A1 GREB1 APOD

2.87e-04181784f8d914fdc06aaa75a4dc9158daf574ca28fa5432
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Ciliated|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CATSPERE MS4A8 DTHD1 PPP1R42

2.87e-041817848eed9d46d924b16f6dd1a025ff612244b02b4391
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRCA1 UPK1A ATAD2 SLC38A8

2.87e-04181784d90faa6115b408c9fbca61fc90ff951e070754ba
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CATSPERE MS4A8 DTHD1 PPP1R42

2.93e-04182784975f6275777fc578eba528e50f69891c66ec44ad
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5A THBD APOD PKHD1L1

2.93e-0418278441b070085edba7a58b81c20aa4942d06f745acf8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5A THBD APOD PKHD1L1

2.93e-041827845e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5A THBD APOD PKHD1L1

2.93e-04182784b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CATSPERE MS4A8 DTHD1 PPP1R42

2.93e-04182784f8c28fa76751062c4cfba0db8af1b377f947f739
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZDHHC21 TNFSF10 INS PKHD1L1

2.99e-041837846c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LIG1 BRCA1 ATAD2 ALG13

2.99e-041837846c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA1 LAMA3 ATAD2 KIF20B

3.11e-0418578430e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

CMIP BRCA1 GREB1 ZRANB3

3.18e-04186784de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

CMIP BRCA1 GREB1 ZRANB3

3.18e-041867840b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell18-Distal-Epithelial-Multiciliated_cell|Distal / Age, Tissue, Lineage and Cell class

CATSPERE MS4A8 DTHD1 PPP1R42

3.24e-041877848d7fa6b2950898e7f283401808378ba2a41b9651
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5A THBD APOD PKHD1L1

3.31e-0418878426915db8863f4115b46a81982e187322e21600fd
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5A THBD APOD PKHD1L1

3.31e-041887843f76c0f912f8f023ea425be7f43593b3d7f967e3
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BRCA1 LAMA3 TEX15 LRRC9

3.31e-041887840476d7ee3e0ce78c3c5b111e9ade01098f9ea7ec
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5A THBD APOD PKHD1L1

3.31e-0418878461ee7b152745164293d8a44ef91ee2393efbdca5
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LIG1 XPO4 ARHGAP35 KIF20B

3.38e-04189784d05e043d0874b8563b9f5514f6c884b35c603e3a
ToppCellT_cells-GZMK+_CD8+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

GPR68 GYG1 ARHGAP35 DTHD1

3.38e-04189784e2ca075aedf7c370ab4ede6272254ffd06cbcdec
ToppCellwk_08-11-Endothelial-Lymph_endothelial-Lymphatic_endo|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

UNC5A TNFSF10 APOD PKHD1L1

3.44e-04190784279c5f68b993dc7adbf9aa69fffb1321cdebc48a
ToppCellPBMC-Severe-cDC_12|Severe / Compartment, Disease Groups and Clusters

LIG1 BRCA1 ATAD2 NUP205

3.44e-0419078484ee185939bdefb10705b621a70da27701eadcee
ToppCellwk_08-11-Endothelial-Lymph_endothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

UNC5A TNFSF10 APOD PKHD1L1

3.44e-04190784d7f1dc032d161529559e01832d1a3112c6f6cc1a
ToppCellMild-T/NK_proliferative|World / Disease group and Cell class

LIG1 BRCA1 ATAD2 KIF20B

3.51e-041917849dba5526fd5ea8065ad305feb2ee562335f887c6
ToppCelldroplet-Spleen-SPLEEN-30m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIG1 BRCA1 ATAD2 KIF20B

3.51e-04191784c8b99bd3a30c81ee4deba9cbf0196920ab3ab550
ToppCellwk_15-18-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TMEM45B MS4A8 DTHD1 PPP1R42

3.51e-04191784e81cd65dbf0ef1c2ab7088f73ce605d456dd3a7a
DrugS-20928

SLC27A1 MTNR1A MTNR1B

7.38e-076773CID000127856
Drugtetrahydrophenanthrene

MTNR1A MTNR1B

1.13e-052772CID000136808
Drug2-chloromelatonin

MTNR1A MTNR1B

1.13e-052772CID000195276
Drugcyclo(Leu-Trp

MTNR1A MTNR1B

1.13e-052772CID003082081
DrugPhenalenes

MTNR1A MTNR1B

1.13e-052772ctd:D043803
DrugN-(2-(2-ethyl-8,9-dihydrofuro(3,2-c)pyrazolo(1,5-a)pyridin-1-yl)ethyl)acetamide

MTNR1A MTNR1B

1.13e-052772ctd:C561057
DrugRamelteon

MTNR1A MTNR1B

1.13e-052772DB00980
DrugLG 100754

INS SLC27A1

1.13e-052772ctd:C101596
Drug3-acetylindole

MTNR1A MTNR1B

1.13e-052772CID000012802
DrugIIK7

MTNR1A MTNR1B

1.13e-052772CID004172142
DrugAgomelatine

MTNR1A MTNR1B

3.38e-053772DB06594
DrugN-Bromoacetyl-2-iodo-5-methoxytryptamine

MTNR1A MTNR1B

3.38e-053772CID000131983
DrugAH-001

MTNR1A MTNR1B

3.38e-053772CID003018920
DrugGR196429

MTNR1A MTNR1B

3.38e-053772CID005311134
DrugN-(2-(2-methoxy-6H-dipyrido(2,3-a-3,2-e)pyrrolizin-11-yl)ethyl)-2-furamide

MTNR1A MTNR1B

3.38e-053772ctd:C550454
Drug2-methyl-6,7-dichloromelatonin

MTNR1A MTNR1B

3.38e-053772CID000128592
DrugAcenaphthenes

MTNR1A MTNR1B

3.38e-053772ctd:D000073
DrugI 392

MTNR1A MTNR1B

3.38e-053772CID005474706
Drug1H-pyrrolo

MTNR1A MTNR1B

3.38e-053772CID000009226
Drugindiplon

THBD INS MTNR1A MTNR1B

4.17e-0557774CID006450813
Drugbeta-methyl-6-chloromelatonin

INS MTNR1A MTNR1B

4.73e-0521773CID000219018
DrugKaempferol [520-18-3]; Down 200; 14uM; MCF7; HT_HG-U133A

AGO3 LAMA3 STAG3 KDM4B ZNF248 TMEM63A

5.08e-051947767196_DN
Drugagomelatine

GPR50 MTNR1A MTNR1B

6.27e-0523773CID000082148
Drug5-methoxyluzindole

MTNR1A MTNR1B

6.74e-054772CID000129776
Drug4,6-difluoromelatonin

MTNR1A MTNR1B

6.74e-054772CID000610660
Drug2,7-dimethoxynaphthalene

MTNR1A MTNR1B

6.74e-054772CID000077021
Drug1,4-benzodioxin

MTNR1A MTNR1B

6.74e-054772CID000136071
Drugramelteon

MTNR1A MTNR1B

6.74e-054772ctd:C495910
Drug2-bromomelatonin

MTNR1A MTNR1B

6.74e-054772CID000126731
DrugK 185

MTNR1A MTNR1B

1.12e-045772CID005311198
Drug5-MCA-NAT

MTNR1A MTNR1B

1.12e-045772CID004284525
DrugDH97

MTNR1A MTNR1B

1.12e-045772CID003467177
DrugAMMTC

MTNR1A MTNR1B

1.12e-045772CID005311004
Drugtetrahydroanthracene

MTNR1A MTNR1B

1.12e-045772CID000035385
DrugSureCN7064917

MTNR1A MTNR1B

1.12e-045772CID010657206
Drug5-methoxy-N-isobutanoyltryptamine

MTNR1A MTNR1B

1.68e-046772CID006455231
Drugphenalene

MTNR1A MTNR1B

1.68e-046772CID000009149
Drugthiochroman

MTNR1A MTNR1B

1.68e-046772CID000137415
Drugacetyl-leucyl-glutamyl-histidyl-aspartal

GJB2 TNFSF10

1.68e-046772ctd:C420218
Drugazide radical

MTNR1A MTNR1B

1.68e-046772CID006857664
Disease3-(3-amino-3-carboxypropyl)uridine measurement

ATAD2 ZHX1

6.04e-062732EFO_0800632
Diseaseischemia (biomarker_via_orthology)

THBD GJB2 MUC2

1.15e-0518733DOID:326 (biomarker_via_orthology)
DiseaseAutism Spectrum Disorders

GPR50 MTNR1A MTNR1B USH2A

6.00e-0585734C1510586
Diseasetype 2 diabetes mellitus (is_marker_for)

THBD INS MTNR1B APOD

3.67e-04136734DOID:9352 (is_marker_for)
DiseaseMalignant Glioma

TNFSF10 CCR4 APOD

7.06e-0470733C0555198
Diseasemixed gliomas

TNFSF10 CCR4 APOD

7.06e-0470733C0259783
Diseasegestational diabetes (is_marker_for)

INS APOD

8.02e-0417732DOID:11714 (is_marker_for)
DiseaseGlioma

TNFSF10 CCR4 APOD

1.33e-0387733C0017638
Diseaseclinical and behavioural ideal cardiovascular health

MTNR1B TMEM18

1.48e-0323732EFO_0007654
DiseaseDiabetes Mellitus, Non-Insulin-Dependent

CMIP INS MTNR1B TMEM18

2.23e-03221734C0011860
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

FEM1B INS TMEM18

2.27e-03105733DOID:9352 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
LCYVNSTINPACYAL

CHRM4

441

P08173
ENYALVYSCTCIIQL

APOD

126

P05090
CLQSIDSGYSYQCIL

C21orf140

201

B9A014
SCCIAFQNLIDYIYE

ERICH6

296

Q7L0X2
SSAAVCQAVLYEILY

ALG13

356

Q9NP73
LEIAVFLNYCTVCNV

CATSPERE

401

Q5SY80
NTNCAVVVLLYYIRS

CXorf65

16

A6NEN9
YTISAALCYATQLVN

ATG14

301

Q6ZNE5
VLQAVRTCYNIYLAS

ARFGEF1

171

Q9Y6D6
ICADAQCVVDIYVNY

ARFGEF2

506

Q9Y6D5
NLVAVCLAAIYSCYE

CMIP

326

Q8IY22
FVLCQYCGLLQIYSA

CCR4

326

P51679
QLENLYAVISQCIYR

ATAD2

1351

Q6PL18
NVTELCYLLIRYCSG

GJB2

206

P29033
QLLTYQLCHTYVRCT

AGO3

781

Q9H9G7
CEQLAVNYRCLVQSY

NWD2

471

Q9ULI1
IVEQCCTSICSLYQL

INS

91

P01308
ELCYQVIYQLCACSD

NUP205

1061

Q92621
QYTTNPVCLLCNYST

LRRC9

201

Q6ZRR7
YAVFVVTYLILACCQ

TMBIM1

141

Q969X1
QVNIYSCNYSVLCRS

LAMA3

986

Q16787
DCYLNLGSQISVCYV

GREB1

1841

Q4ZG55
ITAIAINRYCYICHS

MTNR1B

131

P49286
AIAINRYCYICHSLQ

GPR50

121

Q13585
ECNLYTFLYLVCIST

FEM1B

441

Q9UK73
SVLICCVLNDTYYAP

MUC2

4331

Q02817
ISQCYLAYDETLNVL

KIF20B

456

Q96Q89
ICTLFYPYCQALQTE

KDM4B

686

O94953
VCGNLDYRNLCYVIT

MYL10

206

Q9BUA6
AVLCILSYDTLQYCD

PGAP6

596

Q9HCN3
AYPTCEVVDVQLCYN

TMEM63A

251

O94886
AFYCYVLQVVKLACT

OR4D6

176

Q8NGJ1
SRLLTCYVQDYLECV

ING2

21

Q9H160
DQQLYDPVLVCNSCY

MTMR4

1156

Q9NYA4
SVALYQCQELDTYLI

BRCA1

1841

P38398
CSYVNVLSDLVYTLA

GYG1

271

P46976
CYITAPSYVLQQLEC

DTHD1

186

Q6ZMT9
CCQSSNVSVIYPNIY

MS4A8

211

Q9BY19
QDIYCYDLIQYCLLV

IQCB1

51

Q15051
LCYISNSCQPQSYLV

KRTAP24-1

191

Q3LI83
PDLVCYTDYLQTVIC

IL21R

21

Q9HBE5
TQQVSLCYRLTYQTC

FDXACB1

581

Q9BRP7
IQVQVCLYAFDLIYL

LIG1

651

P18858
ISVCEWYQRVYQSLC

COX6B1

51

P14854
LYENIYISVGFLCCI

GPR68

101

Q15743
DCYVAICSPLLYNVI

OR8G3P

121

P0DMU2
LYSVAYTDVVQLFCI

SLC5A7

181

Q9GZV3
TIYDIQVEVCTIYAC

USH2A

3081

O75445
YQCQPLNQTSYLCVC

THBD

376

P07204
LLYIQSHYQLELQCC

SMG5

126

Q9UPR3
QQINTVCDELYIYCS

SKIL

181

P12757
YCINAYNDTLTATLI

TCAF2

126

A6NFQ2
ACEVRCQNIYLTTGY

NKRF

241

O15226
SVFQVLSVLVVCYYQ

SLC35G2

141

Q8TBE7
VCQVCQYRSSLYSEV

POGZ

591

Q7Z3K3
NLSVLYLYDNCISQI

PPP1R42

51

Q7Z4L9
CFCNECISIIIEQYS

SHPRH

1451

Q149N8
TLAACYLALVITVQY

SLC38A8

181

A6NNN8
CLCLYNSKESLSYVV

ARHGAP35

661

Q9NRY4
SYAALIYLAVCVNAV

SPATA9

151

Q9BWV2
ALSIVAVNYSLVYCL

TMEM45B

226

Q96B21
LCNQYYKLITFICEI

XPO4

976

Q9C0E2
YNVICLTCTVVAVCY

PIGT

526

Q969N2
RTLVCQCQYSLLYDG

STAG3

196

Q9UJ98
YCAILNAVNYISTVL

RINT1

536

Q6NUQ1
CIKYNCTVVQYIGEI

SLC27A1

326

Q6PCB7
YNCTIVQYIGELCRY

SLC27A4

326

Q6P1M0
DVQISCYHILCSLYS

RYR3

3021

Q15413
VVLNSSYVCVECNFL

ZHX1

96

Q9UKY1
CVEANSCSLYQYRLI

PKHD1L1

536

Q86WI1
LIVYIFECASCITSY

UPK1A

101

O00322
VACTSLEYNIRVYCL

UNC5A

601

Q6ZN44
LQLCFYTELLTCYAL

ZDHHC21

136

Q8IVQ6
IICKYNEAVNCSYAI

TEX15

2141

Q9BXT5
LQSLCVAVTYVYFTN

TNFSF10

26

P50591
FLCLVILVYCAEYIN

TMEM18

56

Q96B42
VILENYSNLVSVGYC

ZNF248

36

Q8NDW4
QCSLCTYINNSELPY

ZRANB3

626

Q5FWF4
FNITGIAINRYCYIC

MTNR1A

116

P48039