Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

ATP8B3 ATP7A ATP7B KIF12 ABCC11 CHD1L DICER1 DDX6 STARD9 ATAD2B SHPRH NAV3 MACF1 ATP11A DNAH5 ALPL AFG1L

1.62e-0661414117GO:0140657
GeneOntologyMolecularFunctionATP hydrolysis activity

ATP8B3 ATP7A ATP7B KIF12 ABCC11 CHD1L DDX6 ATAD2B NAV3 MACF1 ATP11A DNAH5 ALPL AFG1L

3.01e-0644114114GO:0016887
GeneOntologyMolecularFunctionP-type divalent copper transporter activity

ATP7A ATP7B

4.95e-0521412GO:0043682
GeneOntologyMolecularFunctionP-type monovalent copper transporter activity

ATP7A ATP7B

4.95e-0521412GO:0140581
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

EMILIN3 LAMC1 FBLN2

7.24e-05121413GO:0030023
GeneOntologyMolecularFunctioncytoskeletal protein binding

HIP1 RARA HDAC6 CENPF RHBG KIF12 PEX14 LCP1 SMTN PPARGC1A DST BMP10 STARD9 NAV3 AIF1 MACF1 DMD CAMSAP1 ALDOB PDLIM2

9.21e-05109914120GO:0008092
GeneOntologyMolecularFunctionstructural molecule activity conferring elasticity

EMILIN3 LAMC1 FBLN2

1.19e-04141413GO:0097493
GeneOntologyMolecularFunctionmicrotubule binding

HDAC6 CENPF KIF12 PEX14 DST STARD9 NAV3 MACF1 CAMSAP1

3.47e-043081419GO:0008017
GeneOntologyMolecularFunctionneuroligin family protein binding

NRXN3 NRXN2

4.88e-0451412GO:0097109
GeneOntologyMolecularFunctionlipid binding

PLEKHB2 HIP1 RARA CARMIL2 RBP3 LAMC1 ITPR2 PLEK2 CPNE6 MVB12A STARD9 PDIA2 PLA2G4F EXOC7 ALDOB GRAMD1C VPS13B

6.10e-0498814117GO:0008289
GeneOntologyMolecularFunctiontubulin binding

HDAC6 CENPF KIF12 PEX14 PPARGC1A DST STARD9 NAV3 MACF1 CAMSAP1

9.40e-0442814110GO:0015631
GeneOntologyBiologicalProcesscell-substrate junction assembly

ITGA6 LAMC1 ACVRL1 DST LRP1 MACF1 SDC4

9.42e-061081417GO:0007044
GeneOntologyBiologicalProcesscell-substrate junction organization

ITGA6 LAMC1 ACVRL1 DST LRP1 MACF1 SDC4

1.42e-051151417GO:0150115
GeneOntologyBiologicalProcesscell-substrate adhesion

ITGA6 LAMB3 LAMC1 ACVRL1 DICER1 FBLN2 LPXN ATXN3 LRP1 MACF1 DMD SDC4

2.57e-0541014112GO:0031589
GeneOntologyBiologicalProcessactin cytoskeleton organization

HIP1 CARMIL2 HDAC6 CARMIL3 ARHGEF18 LCP1 KANK2 SMTN PLEK2 CPNE6 BMP10 ATXN3 LRP1 AIF1 ARHGAP28 PDLIM2 SDC4

3.54e-0580314117GO:0030036
GeneOntologyBiologicalProcessregulation of cell-substrate adhesion

ITGA6 ACVRL1 DICER1 FBLN2 ATXN3 LRP1 MACF1 DMD SDC4

6.44e-052541419GO:0010810
DomainCH

LCP1 SMTN DST NAV3 MACF1 DMD CAMSAP1

1.29e-06731417PS50021
DomainCH-domain

LCP1 SMTN DST NAV3 MACF1 DMD CAMSAP1

1.56e-06751417IPR001715
DomainEGF-like_CS

EPHB4 FAT4 CD248 LAMB3 LAMC1 HHIP FBLN2 NRXN3 NRXN2 LRP1 UMOD

4.77e-0626114111IPR013032
DomainEGF_2

EPHB4 FAT4 CD248 LAMB3 LAMC1 HHIP FBLN2 NRXN3 NRXN2 LRP1 UMOD

5.51e-0626514111PS01186
DomainCH

LCP1 SMTN DST NAV3 MACF1 DMD

9.53e-06651416SM00033
DomainSyndecan

NRXN3 NRXN2 SDC4

1.44e-0571413PF01034
DomainSyndecan/Neurexin_dom

NRXN3 NRXN2 SDC4

1.44e-0571413IPR027789
DomainCH

LCP1 SMTN DST NAV3 MACF1 DMD

1.47e-05701416PF00307
Domain-

LCP1 SMTN DST NAV3 MACF1 DMD

1.59e-057114161.10.418.10
DomainEGF_1

FAT4 CD248 LAMB3 LAMC1 HHIP FBLN2 NRXN3 NRXN2 LRP1 UMOD

2.43e-0525514110PS00022
DomainGrowth_fac_rcpt_

EPHB4 FAT4 CD248 LAMC1 HTRA4 FBLN2 LRP1 UMOD

2.45e-051561418IPR009030
DomainACTININ_2

LCP1 DST MACF1 DMD

2.47e-05231414PS00020
DomainACTININ_1

LCP1 DST MACF1 DMD

2.47e-05231414PS00019
DomainActinin_actin-bd_CS

LCP1 DST MACF1 DMD

2.47e-05231414IPR001589
DomainP-typ_ATPase_IB

ATP7A ATP7B

5.66e-0521412IPR027256
DomainHMA_Cu_ion-bd

ATP7A ATP7B

5.66e-0521412IPR006122
DomainEGF

FAT4 CD248 LAMC1 HHIP FBLN2 NRXN3 NRXN2 LRP1 UMOD

7.52e-052351419SM00181
Domain-

ATP8B3 ATP7A ATP7B ATP11A

9.50e-053214143.40.1110.10
Domain-

ATP8B3 ATP7A ATP7B ATP11A

9.50e-053214142.70.150.10
DomainEGF-like_dom

FAT4 CD248 LAMC1 HHIP FBLN2 NRXN3 NRXN2 LRP1 UMOD

1.17e-042491419IPR000742
DomainATPase_P-typ_cyto_domN

ATP8B3 ATP7A ATP7B ATP11A

1.36e-04351414IPR023299
DomainNeurexin-like

NRXN3 NRXN2 SDC4

1.44e-04141413IPR003585
Domain4.1m

NRXN3 NRXN2 SDC4

1.44e-04141413SM00294
DomainATPase_P-typ_P_site

ATP8B3 ATP7A ATP7B ATP11A

1.52e-04361414IPR018303
DomainP_typ_ATPase

ATP8B3 ATP7A ATP7B ATP11A

1.52e-04361414IPR001757
DomainATPASE_E1_E2

ATP8B3 ATP7A ATP7B ATP11A

1.52e-04361414PS00154
DomainEGF-type_Asp/Asn_hydroxyl_site

FAT4 CD248 FBLN2 NRXN3 LRP1 UMOD

1.53e-041061416IPR000152
DomainCARMIL_C

CARMIL2 CARMIL3

1.69e-0431412IPR031943
DomainLUC7

LUC7L LUC7L2

1.69e-0431412PF03194
DomainCARMIL_C

CARMIL2 CARMIL3

1.69e-0431412PF16000
DomainLuc7-rel

LUC7L LUC7L2

1.69e-0431412IPR004882
DomainHeavy-metal-associated_CS

ATP7A ATP7B

1.69e-0431412IPR017969
DomainATPase_P-typ_transduc_dom_A

ATP8B3 ATP7A ATP7B ATP11A

1.69e-04371414IPR008250
DomainE1-E2_ATPase

ATP8B3 ATP7A ATP7B ATP11A

1.69e-04371414PF00122
DomainHMA

ATP7A ATP7B

3.36e-0441412PF00403
DomainHMA_2

ATP7A ATP7B

3.36e-0441412PS50846
DomainHMA_1

ATP7A ATP7B

3.36e-0441412PS01047
DomainEGF_3

FAT4 CD248 HHIP FBLN2 NRXN3 NRXN2 LRP1 UMOD

4.20e-042351418PS50026
DomainEGF_CA

FAT4 CD248 FBLN2 LRP1 UMOD

4.87e-04861415PF07645
DomainSpectrin

DST MACF1 DMD

6.68e-04231413PF00435
Domain-

DST MACF1

8.32e-04614123.90.1290.10
DomainGAR

DST MACF1

8.32e-0461412PS51460
DomainGAS2

DST MACF1

8.32e-0461412PF02187
Domain-

DST MACF1

8.32e-04614123.30.920.20
DomainGAS_dom

DST MACF1

8.32e-0461412IPR003108
DomainGAS2

DST MACF1

8.32e-0461412SM00243
DomainEGF_Ca-bd_CS

FAT4 CD248 FBLN2 LRP1 UMOD

8.44e-04971415IPR018097
DomainEGF_CA

FAT4 CD248 FBLN2 LRP1 UMOD

9.25e-04991415PS01187
DomainASX_HYDROXYL

FAT4 FBLN2 NRXN3 LRP1 UMOD

9.68e-041001415PS00010
DomainPlectin

DST MACF1

1.16e-0371412PF00681
DomainPlectin_repeat

DST MACF1

1.16e-0371412IPR001101
DomainHMA_dom

ATP7A ATP7B

1.16e-0371412IPR006121
DomainPLEC

DST MACF1

1.16e-0371412SM00250
DomainFHA

STARD9 CEP170B FOXK1

1.20e-03281413SM00240
DomainSpectrin_repeat

DST MACF1 DMD

1.33e-03291413IPR002017
Domain-

ATP8B3 ATP7A ATP7B ATP11A

1.39e-036414143.40.50.1000
DomainFHA

STARD9 CEP170B FOXK1

1.62e-03311413PF00498
DomainSPEC

DST MACF1 DMD

1.78e-03321413SM00150
DomainSpectrin/alpha-actinin

DST MACF1 DMD

1.78e-03321413IPR018159
DomainEGF_CA

FAT4 CD248 FBLN2 LRP1 UMOD

2.34e-031221415SM00179
Domain-

COL6A2 SEC24A CPNE6 VWA5B1

2.38e-037414143.40.50.410
Domain-

STARD9 CEP170B FOXK1

2.51e-033614132.60.200.20
DomainFHA_dom

STARD9 CEP170B FOXK1

2.51e-03361413IPR000253
DomainEGF-like_Ca-bd_dom

FAT4 CD248 FBLN2 LRP1 UMOD

2.51e-031241415IPR001881
DomainEGF

CD248 NRXN3 NRXN2 LRP1 UMOD

2.69e-031261415PF00008
DomainLAM_G_DOMAIN

FAT4 NRXN3 NRXN2

2.93e-03381413PS50025
DomainHAD-like_dom

ATP8B3 ATP7A ATP7B ATP11A

3.02e-03791414IPR023214
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL6A2 CAST ITGA6 LAMB3 EMILIN3 LAMC1 FBLN2 DST BMP10 DMD SDC4

1.30e-0530010411M610
PathwayREACTOME_TYPE_I_HEMIDESMOSOME_ASSEMBLY

ITGA6 LAMB3 DST

6.17e-05111043M27372
PathwayPID_INTEGRIN4_PATHWAY

ITGA6 LAMB3 LAMC1

6.17e-05111043M158
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

ITGA6 LAMB3 LAMC1 DMD SDC4

7.24e-05591045M27218
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

SRPK1 PCARE TEX15 FER1L6 DST MACF1 PPIP5K1 DMD CAMSAP1 DNAH5 VPS13B

4.00e-092341431136243803
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CARMIL2 KLHDC2 SEC24A LAMC1 AKT1S1 DDX6 LUC7L DST STARD9 MACF1 FOXO4 BOD1L1 CAMSAP1 DOCK6 CSPP1 SH3RF3 CEP170B FOXK1

1.81e-088611431836931259
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ATXN7L1 UVSSA HECTD4 CAST TMEM63C ARHGEF18 PEX14 CHD1L RBBP8NL LUC7L SHPRH LRP1 ANKIB1 MACF1 KDM2A BOD1L1 ATP11A DOCK6 USP15 SH3RF3 STAG2 CEP170B VPS13B

4.57e-0814891432328611215
Pubmed

ATP7A and ATP7B copper transporters have distinct functions in the regulation of neuronal dopamine-β-hydroxylase.

ATP7A ATP7B DBH

6.81e-083143330341172
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

LARS1 HEATR5A STARD9 HECW2 ANKIB1 ARHGAP28 BOD1L1 DOCK6

2.51e-07153143810718198
Pubmed

Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.

DST MACF1 DMD

2.71e-07414338954775
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

GATAD2A CENPF SEC24A CAST PEX14 KANK2 DDB1 SMTN DST MACF1 KDM2A CAMSAP1

6.49e-074721431238943005
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

HEATR5A DNAJC6 STARD9 NAV3 MACF1 PPIP5K1 BOD1L1 USP15 CEP170B VPS13B WDR48

1.07e-064071431112693553
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

PLEKHB2 CENPF LAMC1 DST SOHLH1 MACF1 KDM2A CAMSAP1 DNAH5 FOXK1

1.28e-063321431037433992
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

CENPF ARHGEF18 DDB1 DST MACF1 DMD TRIM47 USP15

1.70e-06197143820811636
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UVSSA HECTD4 ZNF507 LARS1 DICER1 GINS1 NRXN3 DST NRXN2 HECW2 ANKIB1 DOCK6

2.12e-065291431214621295
Pubmed

The N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosome.

ITGA6 LAMB3 DST

2.35e-067143310637308
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ATP7B HDAC6 GATAD2A ATXN7L1 EMILIN3 KANK2 DDB1 DICER1 LUC7L2 LRP1 MACF1 TAF5 PDLIM2 CEP170B FOXK1 ALPL WDR48

3.68e-0611161431731753913
Pubmed

EMILIN proteins are novel extracellular constituents of the dentin-pulp complex.

EMILIN3 LAMC1 FBLN2

3.75e-068143332948785
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

HIP1 HDAC6 KLHDC2 HECTD4 LAMC1 DST ATXN3 MACF1 USP15 SDC4 ALPL

5.30e-064811431128190767
Pubmed

Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.

ITGA6 LAMB3 DST

5.61e-069143312482924
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

HIP1 ANP32B PSMB6 LARS1 LAMC1 PEX14 SRPK1 DDB1 EXOSC2 DICER1 DDX6 SMTN ITPR2 LUC7L DST LUC7L2 EXOC7 STAG2 ALPL

7.52e-0614401431930833792
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ZEB1 CENPF ZNF507 LAMC1 RBBP8NL DST LUC7L2 LRP1 CAMSAP1 S100PBP

9.76e-064181431034709266
Pubmed

Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival.

ITGA6 LAMB3 DST

1.10e-051114338707838
Pubmed

The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes.

ITGA6 LAMB3 DST

1.10e-0511143310811835
Pubmed

Interaction of the bullous pemphigoid antigen 1 (BP230) and desmoplakin with intermediate filaments is mediated by distinct sequences within their COOH terminus.

ITGA6 LAMB3 DST

1.10e-0511143312802069
Pubmed

Current insights into the formation and breakdown of hemidesmosomes.

ITGA6 LAMB3 DST

1.10e-0511143316757171
Pubmed

Copper efflux transporters ATP7A and ATP7B: Novel biomarkers for platinum drug resistance and targets for therapy.

ATP7A ATP7B

1.68e-052143229394468
Pubmed

Expression of the Menkes gene homologue in mouse tissues lack of effect of copper on the mRNA levels.

ATP7A ATP7B

1.68e-05214328082762
Pubmed

Rescue of dystrophic skeletal muscle by PGC-1α involves restored expression of dystrophin-associated protein complex components and satellite cell signaling.

PPARGC1A DMD

1.68e-052143223594613
Pubmed

Solution structures of the actuator domain of ATP7A and ATP7B, the Menkes and Wilson disease proteins.

ATP7A ATP7B

1.68e-052143219645496
Pubmed

IL-32 aggravates metabolic disturbance in human nucleus pulposus cells by activating FAT4-mediated Hippo/YAP signaling.

FAT4 IL32

1.68e-052143239178518
Pubmed

Differential intracellular localisation of the Menkes and Wilson copper transporting ATPases in the third trimester human placenta.

ATP7A ATP7B

1.68e-052143221115196
Pubmed

PGC-1alpha regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy.

PPARGC1A DMD

1.68e-052143217403779
Pubmed

Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.

DST MACF1

1.68e-052143211002341
Pubmed

Mechanisms of charge transfer in human copper ATPases ATP7A and ATP7B.

ATP7A ATP7B

1.68e-052143228164426
Pubmed

Biochemical basis of regulation of human copper-transporting ATPases.

ATP7A ATP7B

1.68e-052143217562324
Pubmed

Genes regulating copper metabolism.

ATP7A ATP7B

1.68e-05214329823011
Pubmed

GINS1 promotes ZEB1-mediated epithelial-mesenchymal transition and tumor metastasis via β-catenin signaling in hepatocellular carcinoma.

ZEB1 GINS1

1.68e-052143238468464
Pubmed

Overexpression of a calpastatin transgene in mdx muscle reduces dystrophic pathology.

CAST DMD

1.68e-052143212354790
Pubmed

Molecular pathogenesis of Wilson and Menkes disease: correlation of mutations with molecular defects and disease phenotypes.

ATP7A ATP7B

1.68e-052143217717039
Pubmed

Peroxisome proliferator-activated receptor γ coactivator1- gene α transfer restores mitochondrial biomass and improves mitochondrial calcium handling in post-necrotic mdx mouse skeletal muscle.

PPARGC1A DMD

1.68e-052143222907054
Pubmed

Syndecan-4 deficiency increases susceptibility to kappa-carrageenan-induced renal damage.

UMOD SDC4

1.68e-052143211304570
Pubmed

Genetic polymorphisms of copper- and platinum drug-efflux transporters ATP7A and ATP7B in Japanese cancer patients.

ATP7A ATP7B

1.68e-052143220045993
Pubmed

Regulation of the apico-basolateral trafficking polarity of the homologous copper-ATPases ATP7A and ATP7B.

ATP7A ATP7B

1.68e-052143238032054
Pubmed

Molecular features of copper binding proteins involved in copper homeostasis.

ATP7A ATP7B

1.68e-052143227896900
Pubmed

Dynamics of the metal binding domains and regulation of the human copper transporters ATP7B and ATP7A.

ATP7A ATP7B

1.68e-052143228271598
Pubmed

[Structure and function of ATP7A and ATP7B proteins--Cu-transporting ATPases].

ATP7A ATP7B

1.68e-052143221117320
Pubmed

[From gene to disease: copper-transporting P ATPases alteration].

ATP7A ATP7B

1.68e-052143219046832
Pubmed

A mutation in the ATP7B copper transporter causes reduced dopamine beta-hydroxylase and norepinephrine in mouse adrenal.

ATP7B DBH

1.68e-052143212718440
Pubmed

Expression in mouse kidney of membrane copper transporters Atp7a and Atp7b.

ATP7A ATP7B

1.68e-052143212372948
Pubmed

Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells.

ATP7A ATP7B

1.68e-052143218565219
Pubmed

Copper transporting P-type ATPases and human disease.

ATP7A ATP7B

1.68e-052143212539960
Pubmed

Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in plasma enzyme activities as novel organ-specific disease models.

DMD ALPL

1.68e-052143219151073
Pubmed

Hormonal regulation of the Menkes and Wilson copper-transporting ATPases in human placental Jeg-3 cells.

ATP7A ATP7B

1.68e-052143217109627
Pubmed

Quantitative relationship between mutated amino-acid sequence of human copper-transporting ATPases and their related diseases.

ATP7A ATP7B

1.68e-052143218688737
Pubmed

Rescue of dystrophic skeletal muscle by PGC-1α involves a fast to slow fiber type shift in the mdx mouse.

PPARGC1A DMD

1.68e-052143222253880
Pubmed

Meiotic maturation failure induced by DICER1 deficiency is derived from primary oocyte ooplasm.

DICER1 ALPL

1.68e-052143219129368
Pubmed

Expression and localization of menkes and Wilson copper transporting ATPases in human placenta.

ATP7A ATP7B

1.68e-052143215135234
Pubmed

Developmental expression of the mouse mottled and toxic milk genes suggests distinct functions for the Menkes and Wilson disease copper transporters.

ATP7A ATP7B

1.68e-05214329215673
Pubmed

ZEB1 protects skeletal muscle from damage and is required for its regeneration.

ZEB1 DMD

1.68e-052143230910999
Pubmed

Copper-transporting ATPases ATP7A and ATP7B: cousins, not twins.

ATP7A ATP7B

1.68e-052143218000748
Pubmed

Menkes disease: recent advances and new insights into copper metabolism.

ATP7A ATP7B

1.68e-05214328732640
Pubmed

Trafficking of the copper-ATPases, ATP7A and ATP7B: role in copper homeostasis.

ATP7A ATP7B

1.68e-052143217531189
Pubmed

Myogenic stem cell function is impaired in mice lacking the forkhead/winged helix protein MNF.

DMD FOXK1

1.68e-052143210792059
Pubmed

Intracellular targeting of copper-transporting ATPase ATP7A in a normal and Atp7b-/- kidney.

ATP7A ATP7B

1.68e-052143217928409
Pubmed

RFX2 is a candidate downstream amplifier of A-MYB regulation in mouse spermatogenesis.

RFX2 MYBL1

1.68e-052143220003220
Pubmed

Involvement of Ataxin-3 (ATXN3) in the malignant progression of pancreatic cancer via deubiquitinating HDAC6.

HDAC6 ATXN3

1.68e-052143237460341
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

HDAC6 GATAD2A ANP32B SEC24A PSMB6 CAST LARS1 SRPK1 PFAS DDB1 EXOSC2 DDX6 LUC7L LUC7L2 MACF1 TRIM47 STAG2 FOXK1

2.17e-0514151431828515276
Pubmed

The contribution of rare and common variants in 30 genes to risk nicotine dependence.

DBH NRXN3 NRXN2

2.40e-0514143325450229
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

PFAS KANK2 DICER1 DST MACF1 CAMSAP1 CEP170B

2.68e-05209143736779422
Pubmed

Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.

ITGA6 LAMB3 LAMC1

3.66e-0516143317601529
Pubmed

An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.

GATAD2A PSMB6 RFX2 DDB1 ZNF513

3.83e-0591143520362542
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

CENPF DST LUC7L2 MACF1 DMD EXOC7

3.97e-05151143617043677
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

DICER1 DST NRXN2 MACF1 KDM2A USP15 WDR48

4.29e-05225143712168954
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

KRT72 HIP1 LAMC1 PFAS KANK2 MVB12A ATXN3 ANKIB1 USP15 PDLIM2 SDC4

4.33e-056041431138803224
Pubmed

Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca2+ Influx.

NRXN3 NRXN2

5.02e-053143238891114
Pubmed

Calpain-mediated ataxin-3 cleavage in the molecular pathogenesis of spinocerebellar ataxia type 3 (SCA3).

CAST ATXN3

5.02e-053143223100324
Pubmed

Novel functions and targets of miR-944 in human cervical cancer cells.

HECW2 S100PBP

5.02e-053143225156441
Pubmed

Expression of the mouse Macf2 gene during inner ear development.

DST MACF1

5.02e-053143212399109
Pubmed

Regulation of the ALK1 ligands, BMP9 and BMP10.

ACVRL1 BMP10

5.02e-053143227528761
Pubmed

Cell Migration and Invadopodia Formation Require a Membrane-binding Domain of CARMIL2.

CARMIL2 CARMIL3

5.02e-053143226578515
Pubmed

FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3.

ATXN3 FOXO4

5.02e-053143221536589
Pubmed

alpha-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junction.

NRXN3 NRXN2

5.02e-053143216406382
Pubmed

Association between polymorphisms in CTR1, CTR2, ATP7A, and ATP7B and platinum resistance in epithelial ovarian cancer.

ATP7A ATP7B

5.02e-053143228737129
Pubmed

Functional analyses of human LUC7-like proteins involved in splicing regulation and myeloid neoplasms.

LUC7L LUC7L2

5.02e-053143233852859
Pubmed

Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses.

NRXN3 NRXN2

5.02e-053143231005376
Pubmed

Dicer1 is required for differentiation of the mouse male germline.

DICER1 ALPL

5.02e-053143218633141
Pubmed

The copper-transporting ATPases, menkes and wilson disease proteins, have distinct roles in adult and developing cerebellum.

ATP7A ATP7B

5.02e-053143215634671
Pubmed

ACVRL1 drives resistance to multitarget tyrosine kinase inhibitors in colorectal cancer by promoting USP15-mediated GPX2 stabilization.

ACVRL1 USP15

5.02e-053143237743483
Pubmed

Interaction of the copper chaperone HAH1 with the Wilson disease protein is essential for copper homeostasis.

ATP7A ATP7B

5.02e-053143210557326
Pubmed

Caspase-12 ablation preserves muscle function in the mdx mouse.

CASP12 DMD

5.02e-053143224879640
Pubmed

Role of glutaredoxin1 and glutathione in regulating the activity of the copper-transporting P-type ATPases, ATP7A and ATP7B.

ATP7A ATP7B

5.02e-053143220566629
Pubmed

Characterization of the interaction between the Wilson and Menkes disease proteins and the cytoplasmic copper chaperone, HAH1p.

ATP7A ATP7B

5.02e-053143210497213
Pubmed

Regulated Dynamic Trafficking of Neurexins Inside and Outside of Synaptic Terminals.

NRXN3 NRXN2

5.02e-053143226446217
Pubmed

Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity.

NRXN3 NRXN2

5.02e-053143211944992
Pubmed

MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis.

DICER1 ALPL

5.02e-053143218320056
Pubmed

Alternative splicing of neurexins 1-3 is modulated by neuroinflammation in the prefrontal cortex of a murine model of multiple sclerosis.

NRXN3 NRXN2

5.02e-053143233058888
Pubmed

Important contribution of alpha-neurexins to Ca2+-triggered exocytosis of secretory granules.

NRXN3 NRXN2

5.02e-053143217035546
Pubmed

Neurexins: three genes and 1001 products.

NRXN3 NRXN2

5.02e-05314329448462
Pubmed

Deletion of α-neurexin II results in autism-related behaviors in mice.

NRXN3 NRXN2

5.02e-053143225423136
Pubmed

Resveratrol induces expression of the slow, oxidative phenotype in mdx mouse muscle together with enhanced activity of the SIRT1-PGC-1α axis.

PPARGC1A DMD

5.02e-053143224760981
Pubmed

Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior.

NRXN3 NRXN2

5.02e-053143234133920
Pubmed

Developmental expression of laminin-5 and HD1 in the intestine: epithelial to mesenchymal shift for the laminin gamma-2 chain subunit deposition.

LAMB3 LAMC1

5.02e-05314329019243
Pubmed

The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice.

NRXN3 NRXN2

5.02e-053143230858964
InteractionPPIA interactions

HDAC6 GATAD2A CENPF SEC24A CAST PEX14 SRPK1 HEATR5A KANK2 DDB1 DDX6 SMTN DST STARD9 ATXN3 MACF1 KDM2A DMD CAMSAP1 USP15

4.26e-0688814220int:PPIA
GeneFamilyATPase copper transporting

ATP7A ATP7B

2.56e-0529221212
GeneFamilyEF-hand domain containing|Plakins

DST MACF1

7.03e-048922939
CoexpressionGSE17721_LPS_VS_PAM3CSK4_12H_BMDC_UP

PSMB6 EMILIN3 M1AP LPXN ANKIB1 AIF1 USP15 SDC4 WDR48

1.62e-062001439M3925
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

ZEB1 CENPF SEC24A ITGA6 LAMC1 PEX14 DICER1 GINS1 DST ATAD2B NAV3 MACF1 DMD USP15 STAG2 VPS13B MYBL1

4.54e-0685614317M4500
CoexpressionFAN_EMBRYONIC_CTX_BIG_GROUPS_BRAIN_ENDOTHELIAL

COL6A2 IL32 ZEB1 CD248 CAST LAMC1 ACVRL1 KANK2 SMTN DOCK6 PDLIM2

5.51e-0636514311M39018
CoexpressionBROWNE_HCMV_INFECTION_8HR_DN

GINS1 DST ATAD2B LPXN NAV3

6.39e-06481435M7846
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN

PEX14 DST NAV3 DMD USP15 VPS13B

6.80e-06841436M13008
CoexpressionHALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

COL6A2 IL32 MXRA5 LAMC1 FBLN2 DST LRP1 SDC4

1.47e-052001438M5930
CoexpressionBUSSLINGER_ESOPHAGEAL_PROLIFERATING_BASAL_CELLS

CENPF ANP32B ITGA6 LAMB3 DST

4.10e-05701435M40002
CoexpressionFAN_EMBRYONIC_CTX_BRAIN_ENDOTHELIAL_2

COL6A2 ZEB1 CD248 LAMC1 KANK2 SMTN DMD DOCK6 PDLIM2

4.51e-053031439M39040
CoexpressionHELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS

IL32 SMTN LRP1 DMD SDC4

6.49e-05771435M19128
CoexpressionCUI_TCF21_TARGETS_2_DN

HIP1 ATP7A ATXN7L1 CAST ARHGEF18 HEATR5A NRROS DST LUC7L2 HECW2 UMOD MACF1 ARHGAP28 PDLIM2 STAG2

6.96e-0585414315M1533
CoexpressionRICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_DN

TGIF2 CENPF CSPP1

8.45e-05161433M17006
CoexpressionPOOLA_INVASIVE_BREAST_CANCER_DN

LAMB3 SEZ6L2 DST PPIP5K1 EXOC7 SDC4

9.22e-051331436M6767
CoexpressionGSE18804_SPLEEN_MACROPHAGE_VS_BRAIN_TUMORAL_MACROPHAGE_UP

NRDE2 IL32 PLEK2 BOD1L1 TAF5 SDC4 WDR48

1.04e-041961437M10014
CoexpressionCUI_TCF21_TARGETS_2_DN

HIP1 ATP7A ATXN7L1 CAST ARHGEF18 HEATR5A NRROS DST LUC7L2 HECW2 UMOD MACF1 ARHGAP28 PDLIM2 STAG2

1.07e-0488814315MM1018
CoexpressionGSE29949_CD8_NEG_DC_SPLEEN_VS_CD8_POS_DC_SPLEEN_UP

MXRA5 ATP7B LAMC1 DBH BMP10 LRP1 FOXO4

1.14e-041991437M8390
CoexpressionGSE41978_ID2_KO_AND_BIM_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN

KANK2 KCNF1 LUC7L2 CAMSAP1 SDC4 MYBL1 S100PBP

1.14e-041991437M9567
CoexpressionGSE28726_NAIVE_CD4_TCELL_VS_NAIVE_NKTCELL_DN

TREX1 HDAC6 ITGA6 ARHGEF18 AIF1 FOXO4 KDM2A

1.18e-042001437M8311
CoexpressionGSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_CORD_BLOOD_DN

TREX1 CENPF TEX15 NRROS LRP1 SESN2 S100PBP

1.18e-042001437M7177
CoexpressionGSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_UP

TREX1 ATP7A CENPF NRROS STARD9 LRP1 LRRC75A

1.18e-042001437M7168
CoexpressionGSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP

CAST HEATR5A NRROS LCP1 STARD9 STAG2 S100PBP

1.18e-042001437M6044
CoexpressionGSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_6H_IFNA_STIM_DN

HIP1 CARMIL2 EMILIN3 LAMC1 FBLN2 KCNF1 ALPL

1.18e-042001437M7415
CoexpressionGSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN

HIP1 TM9SF1 HEATR5A LCP1 SLFN12L GRAMD1C MYBL1

1.18e-042001437M6513
CoexpressionBROWNE_HCMV_INFECTION_2HR_DN

CENPF ITGA6 DST LPXN

1.37e-04481434M521
CoexpressionNABA_MATRISOME_BLEO_FIBROTIC_LUNG

COL6A2 LAMB3 LAMC1

1.69e-04201433MM17053
CoexpressionAtlasdev gonad_e13.5_F_DevVascOvary_Flk_top-relative-expression-ranked_1000

FAT4 HIP1 ZEB1 ITGA6 LAMC1 ACVRL1 NRROS LCP1 SMTN ITPR2 USHBP1 STARD9 HECW2 NAV3 AIF1 MACF1 ARHGAP28 DOCK6

9.27e-0683114018gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_1000
ToppCellControl_saline-Endothelial-Endothelial-Gen_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

EPHB4 FAT4 ZEB1 ITGA6 ACVRL1 NRROS DST USHBP1 MACF1 DOCK6

1.03e-09200143103b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A2 FAT4 ZEB1 LAMC1 FBLN2 STARD9 NAV3 LRP1 SH3RF3

1.80e-082001439b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

EPHB4 FAT4 ZEB1 ITGA6 ACVRL1 NRROS DST USHBP1 DOCK6

1.80e-082001439b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

EPHB4 ZEB1 ITGA6 ACVRL1 NRROS DST USHBP1 MACF1 DOCK6

1.80e-0820014394bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A2 FAT4 ZEB1 LAMC1 FBLN2 STARD9 NAV3 LRP1 SH3RF3

1.80e-0820014390c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

EPHB4 FAT4 ZEB1 ITGA6 ACVRL1 DST USHBP1 MACF1 DOCK6

1.80e-082001439dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

EPHB4 FAT4 ZEB1 ITGA6 ACVRL1 NRROS USHBP1 MACF1 DOCK6

1.80e-082001439eb94a5111ef0e903ee5be9f7efe571b4e6d5fce1
ToppCellLPS_only-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

EPHB4 ZEB1 ITGA6 ACVRL1 NRROS DST USHBP1 MACF1 DOCK6

1.80e-08200143981e76508c9050d533853d5fd2f3097b27613d836
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

EPHB4 FAT4 ZEB1 ITGA6 ACVRL1 DST USHBP1 MACF1 DOCK6

1.80e-082001439a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A2 ZEB1 KIAA1210 HHIP FBLN2 NAV3 LRP1 DMD

1.76e-071881438ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellGlobus_pallidus-Endothelial|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

EPHB4 CD248 CAST KANK2 SMTN CASP12 TRIM47 DOCK6

1.83e-071891438ad7dc9d25edd68fb624380a082c389fe7d640e7d
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 ZEB1 ITGA6 ACVRL1 NRROS USHBP1 HECW2 DOCK6

2.07e-071921438c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 ZEB1 ITGA6 ACVRL1 NRROS USHBP1 HECW2 DOCK6

2.07e-07192143804f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

EPHB4 FAT4 ZEB1 ITGA6 NRXN3 HECW2 NAV3 DOCK6

2.24e-07194143868004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 ZEB1 ITGA6 ACVRL1 DST HECW2 MACF1 DOCK6

2.24e-0719414380b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HDAC6 CARMIL3 KIF12 SEZ6L2 DDB1 DST MACF1 BOD1L1

2.32e-0719514387796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A2 FAT4 CD248 LAMC1 FBLN2 DST NAV3 LRP1

2.32e-071951438f54bc4454270ff06e85596f98199372b50d0179f
ToppCellIPF-Stromal-Myofibroblast|IPF / Disease state, Lineage and Cell class

COL6A2 FAT4 MXRA5 CD248 LAMC1 KANK2 FBLN2 NAV3

2.42e-0719614382d0a48e49b3b37bb66e33e74c52915911e1f8a74
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FAT4 MXRA5 CD248 TM9SF1 LAMC1 KANK2 STARD9 PDLIM2

2.51e-0719714382872a78b1be61aa1d50bc9a49294a21e922dc033
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL6A2 FAT4 MXRA5 CD248 LAMC1 KANK2 HHIP LRP1

2.61e-07198143875d104eead681f6bf47c4dd24913cc768c9a1717
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

EPHB4 IL32 ZEB1 ITGA6 ACVRL1 USHBP1 HECW2 DOCK6

2.71e-071991438243b7c72f83c12a34d8ea300fca63b04216268a4
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DDX6 LUC7L SLFN12L ATAD2B MACF1 USP15 VPS13B MYBL1

2.71e-071991438f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

EPHB4 ZEB1 ITGA6 ACVRL1 DST USHBP1 MACF1 DOCK6

2.82e-0720014385c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellLPS_anti-TNF-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

EPHB4 ZEB1 ITGA6 ACVRL1 NRROS DST USHBP1 DOCK6

2.82e-0720014381d105eeda5a2c51f9a4654ffc79b7e2348ad593b
ToppCellLPS_anti-TNF-Endothelial-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

EPHB4 ZEB1 ITGA6 ACVRL1 NRROS DST USHBP1 DOCK6

2.82e-07200143860d2cbf41f37f1b11eddb4c9d9246c9c1fc5a5af
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

EPHB4 ZEB1 ITGA6 ACVRL1 DST USHBP1 MACF1 DOCK6

2.82e-07200143872ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A2 FAT4 ZEB1 LAMC1 FBLN2 STARD9 NAV3 LRP1

2.82e-0720014383dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLEKHB2 LAMB3 TEX15 RBBP8NL PPIP5K1 ATP11A SDC4

1.12e-061661437575c325db88d6909cdf0d5e664bd9098b89d4401
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CARMIL2 CENPF ARHGEF18 SRPK1 CHD1L TAF5 MYBL1

1.17e-061671437754e6412d3b9cc0b126e59593df2f5956b4712ef
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHBG ITGA6 FER1L6 ITPR2 PLEK2 ARHGAP28 VWA5B1

1.27e-0616914374b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHBG ITGA6 FER1L6 ITPR2 PLEK2 ARHGAP28 VWA5B1

1.27e-061691437a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RHBG ITGA6 FER1L6 ITPR2 NRXN3 ARHGAP28 VWA5B1

1.48e-0617314370bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEK2 FBLN2 DST USHBP1 TRIM47 ALDOB ALPL

1.86e-061791437a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Proliferative_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

ZEB1 ACVRL1 NRROS USHBP1 HECW2 ALDOB MYBL1

1.86e-061791437d24513a404c9b1d37dd47aa1cdb5713b64b88f89
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAT4 PLEK2 FBLN2 DMD TRIM47 ALDOB ALPL

2.15e-061831437351d575339038bd4a66f408da518c567444208e8
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHB4 ITGA6 ACVRL1 PLEK2 FBLN2 USHBP1 TRIM47

2.40e-061861437b80aaeebc03a318052076d2f02c123f5ddc5e73a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RHBG ITGA6 ITPR2 PPARGC1A NRXN3 DST VWA5B1

2.40e-061861437a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHB4 ITGA6 ACVRL1 PLEK2 FBLN2 USHBP1 TRIM47

2.40e-0618614378a8ed1502542d4895cba3fd5d534256206578716
ToppCellFrontal_cortex-Endothelial|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

EPHB4 CD248 KANK2 SMTN CASP12 TRIM47 DOCK6

2.57e-061881437a43392dbd10fc7dbfb31be39b8af8a7ea121c894
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB4 IL32 ITGA6 ACVRL1 USHBP1 HECW2 DOCK6

2.57e-0618814370026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RHBG ITGA6 ITPR2 PPARGC1A NRXN3 DST VWA5B1

2.57e-061881437e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA6 ACVRL1 PLEK2 FBLN2 DST USHBP1 TRIM47

2.76e-061901437d87b9e9ca863270a9c7f61674271a6440c97d1f4
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 ZEB1 ACVRL1 STARD9 HECW2 DOCK6 CSPP1

2.76e-0619014370e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL32 ZEB1 CD248 ZNF507 ITGA6 SLFN12L FBLN2

2.86e-061911437696921a4f160b6b55698652488ed781e855e5e51
ToppCellPSB-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ATP7A ITPR2 KIAA1210 PPARGC1A DST USHBP1 NAV3

2.86e-0619114378f4637e801554e2343b974fe7794f01dd2151418
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 CD248 LAMC1 HTRA4 FBLN2 LRP1 PDLIM2

2.86e-0619114371efb47743b6834b64cb0f61721ddbe875b1a66ca
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 CD248 LAMC1 HTRA4 FBLN2 LRP1 PDLIM2

2.96e-061921437136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 CD248 LAMC1 HTRA4 FBLN2 LRP1 PDLIM2

2.96e-0619214375e6f8206ee0b10cdba79a7c4a05452cb025a5512
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA6 ACVRL1 PLEK2 FBLN2 DST USHBP1 TRIM47

2.96e-061921437285a9d332a1e07b94f222d4b518dd56928b9e075
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZEB1 ITGA6 ACVRL1 NRXN3 HECW2 NAV3 DOCK6

3.06e-061931437ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPHB4 ITGA6 ACVRL1 FBLN2 NRXN3 DST TRIM47

3.06e-06193143758c590dd6f21bc7ae58ae1729dd574c0f1069592
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL6A2 FAT4 KANK2 SMTN HHIP ARHGAP28 DMD

3.06e-061931437146e8c148478ab61b1c1dbaf1ee98a8cd4a0ff8a
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 CD248 LAMC1 HTRA4 FBLN2 LRP1 PDLIM2

3.06e-0619314370a665531d581d4e3941e29d3f95569da8f166447
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 ZEB1 ITGA6 ACVRL1 USHBP1 HECW2 DOCK6

3.06e-06193143702f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 ZEB1 ITGA6 ACVRL1 USHBP1 HECW2 DOCK6

3.06e-0619314375122b1ffba42de190061be34ecdc6176f84e56a3
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 CD248 LAMC1 HTRA4 FBLN2 LRP1 PDLIM2

3.06e-06193143724ce1f37cca655415410d2403a52d1ebb3332280
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 ZEB1 ITGA6 ACVRL1 DST HECW2 DOCK6

3.17e-06194143743f92b0533e26633dc94cce554045d641ef8fd76
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 ZEB1 ITGA6 ACVRL1 DST HECW2 DOCK6

3.17e-0619414371d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellfacs-Heart-RA-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 CD248 LAMC1 KANK2 NRXN2 LRP1 PDLIM2

3.17e-061941437bc945450b350f597c3ff910d3a14a533d90086a8
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 CD248 LAMC1 HTRA4 FBLN2 LRP1 PDLIM2

3.17e-0619414372d0cff9dc538a14518741e2a96d9d78442c81a72
ToppCellfacs-Heart-LA-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 ZEB1 CD248 LAMC1 FBLN2 LRP1 PDLIM2

3.28e-06195143779a6e8e6de040ff07539e8901fc407363a50e355
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-Late_cap|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EPHB4 IL32 ITGA6 ACVRL1 USHBP1 HECW2 DOCK6

3.28e-061951437dfc5da514fb34a2c318a5c4c61f44049fa43960e
ToppCellfacs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 CD248 LAMC1 FBLN2 NRXN2 LRP1 PDLIM2

3.28e-061951437690d6e15d7c863fc8f2d33b1f7bf86f019f415c9
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HDAC6 CARMIL3 KIF12 SEZ6L2 DST MACF1 BOD1L1

3.28e-0619514373e519cffa6144a62b06124642a14c9ff39b76554
ToppCellPosterior_cortex-Endothelial|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

EPHB4 CD248 KANK2 SMTN CASP12 TRIM47 DOCK6

3.28e-061951437988e3449691cc228cb55e5e30355136c97b12262
ToppCellfacs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 CD248 LAMC1 FBLN2 NRXN2 LRP1 PDLIM2

3.28e-0619514375c05e2bcea3d5d7ebe6325f7187ccf83301053d8
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL32 ZEB1 ZNF507 ITGA6 DDX6 SLFN12L MYBL1

3.39e-061961437c4e7133c609bcbc48c4947ea0aa1a7d9d7251b04
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB4 ZEB1 STARD9 HECW2 NAV3 DOCK6 SH3RF3

3.39e-061961437ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCellfacs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 ZEB1 CD248 LAMC1 FBLN2 LRP1 PDLIM2

3.39e-061961437ad1838dabd043cb140260843e3527d8c7d58850e
ToppCellCOVID-19-lung-Capillary_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

FAT4 ZEB1 ITGA6 ACVRL1 NRXN3 HECW2 DOCK6

3.39e-061961437ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL6A2 LAMC1 FBLN2 DST NAV3 MACF1 ARHGAP28

3.39e-0619614377d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellfacs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A2 ZEB1 CD248 LAMC1 FBLN2 LRP1 PDLIM2

3.39e-061961437cbc15c0769016fe9972445169029bd8d14a7e6ef
ToppCellCOVID_non-vent-Lymphocytic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

IL32 ZNF507 ITGA6 DDX6 SLFN12L MACF1 MYBL1

3.51e-061971437c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL6A2 MXRA5 ZEB1 LAMC1 HHIP ARHGAP28 DNAH5

3.51e-0619714371da8ba5bbab232add6e43ad78b15c2339d0c2bc3
ToppCellCOVID-19-lung-Capillary_1|lung / Disease (COVID-19 only), tissue and cell type

FAT4 ZEB1 ITGA6 ACVRL1 NRXN3 HECW2 DOCK6

3.51e-0619714377e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL6A2 MXRA5 ZEB1 LAMC1 HHIP ARHGAP28 DNAH5

3.51e-061971437d9e196c8b4a6ede4733946dbdba3331534954beb
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A2 FAT4 ZEB1 FBLN2 KCNF1 NAV3 SH3RF3

3.51e-06197143744673c38384453207871d3fd8e8ba9093cc06bc5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB4 ZEB1 STARD9 HECW2 NAV3 DOCK6 SH3RF3

3.51e-061971437cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellwk_15-18-Epithelial-Distal_epithelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KIF12 LAMB3 RBBP8NL GLDC ATP11A DMD SDC4

3.51e-061971437b7aff83c27606d87565382a768119a863fe1c294
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB4 ZEB1 STARD9 HECW2 NAV3 DOCK6 SH3RF3

3.51e-061971437412cb5f37df57121ddd1492021445479c7cbccbf
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB4 IL32 ITGA6 ACVRL1 USHBP1 HECW2 DOCK6

3.51e-061971437b18f2c14d6720f6ae8520c0800356f4a57393ad3
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-Late_cap|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

EPHB4 IL32 ITGA6 ACVRL1 USHBP1 HECW2 DOCK6

3.51e-061971437797ea1c9f75f88b51fdfc17a2b27ed0199ae64c9
ToppCell18-Airway-Endothelial-Endothelial|Airway / Age, Tissue, Lineage and Cell class

EPHB4 IL32 ITGA6 ACVRL1 USHBP1 HECW2 DOCK6

3.63e-06198143770d3ea0837dd6ad62abdf349e566a2e62c8e345a
ToppCellwk_15-18-Endothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EPHB4 ZEB1 ITGA6 ACVRL1 USHBP1 HECW2 DOCK6

3.63e-061981437dcf453e22dba90c0ae349fa6c3d4c20758bb95af
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL6A2 FAT4 MXRA5 LAMC1 HHIP LRP1 ALPL

3.63e-06198143709be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-intermediate_cap|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

IL32 ZEB1 ITGA6 ACVRL1 USHBP1 HECW2 DOCK6

3.63e-06198143775270600b5b29187dfa86f01f8f927ae0621cda4
ToppCell18-Airway-Endothelial|Airway / Age, Tissue, Lineage and Cell class

EPHB4 IL32 ITGA6 ACVRL1 USHBP1 HECW2 DOCK6

3.63e-0619814376b7f1b352dc3a803af87106ffb63944bd4286dfe
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL6A2 LAMC1 KANK2 SMTN HHIP DST DMD

3.75e-061991437e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

COL6A2 FAT4 KANK2 HHIP DST LRP1 DMD

3.75e-06199143738cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-tip_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

EPHB4 IL32 ITGA6 LAMC1 ACVRL1 ARHGAP28 DOCK6

3.75e-0619914371c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCellwk_20-22-Endothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

EPHB4 ZEB1 ITGA6 ACVRL1 USHBP1 HECW2 DOCK6

3.75e-06199143707be9509a8ec9c9a7d721912d77c20e841f49808
ToppCellFibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

COL6A2 MXRA5 CD248 LAMC1 KANK2 DST LRP1

3.75e-06199143740de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB4 IL32 ITGA6 ACVRL1 USHBP1 HECW2 DOCK6

3.75e-061991437f0bf75bfae7b288ecb6801be458b03ebd0108ea7
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LAMC1 ACVRL1 SMTN USHBP1 HECW2 DOCK6 ALPL

3.75e-061991437463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CAST DDX6 ATAD2B MACF1 KDM2A BOD1L1 USP15

3.87e-06200143712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB4 ZEB1 ACVRL1 FBLN2 USHBP1 HECW2 DOCK6

3.87e-0620014372e47888e041ec3d265425d1df97b6665c6da889c
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A2 FAT4 ZEB1 LAMC1 STARD9 NAV3 LRP1

3.87e-062001437c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuroepithelial|5w / Sample Type, Dataset, Time_group, and Cell type.

COL6A2 MXRA5 CD248 EMILIN3 KANK2 ITPR2 FBLN2

3.87e-06200143769707f9576d326a06faac49701ef5cd632e760f6
ToppCellLPS_IL1RA_TNF-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

EPHB4 ZEB1 ITGA6 ACVRL1 NRROS USHBP1 DOCK6

3.87e-062001437d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCellFibroblast|World / shred by cell class for parenchyma

COL6A2 MXRA5 CD248 FBLN2 DST LRP1 PDLIM2

3.87e-062001437dec9ce1bc2571197003596f32e5f742ede72aa79
DrugVitexin [3681-93-4]; Up 200; 9.2uM; HL60; HT_HG-U133A

FAT4 SEC24A TEX15 RFX2 EXOSC2 CAMSAP1 EXOC7 DOCK6 CEP170B WDR48

5.17e-07198143102155_UP
DiseaseMuscular Dystrophy, Animal

PPARGC1A DMD

2.27e-0521412C0026851
Diseaseoccipital horn syndrome (implicated_via_orthology)

ATP7A ATP7B

2.27e-0521412DOID:0111272 (implicated_via_orthology)
DiseaseColorectal Carcinoma

ATP7B CD248 RBP3 LAMB3 LAMC1 SMTN CNPPD1 HHIP FBLN2 LRP1 KDM2A SESN2 DMD

3.41e-0570214113C0009402
Diseaseknee injury

DBH FER1L6

6.78e-0531412EFO_0009507
Diseasehereditary hemorrhagic telangiectasia (implicated_via_orthology)

ACVRL1 BMP10

6.78e-0531412DOID:1270 (implicated_via_orthology)
Diseasejunctional epidermolysis bullosa Herlitz type (implicated_via_orthology)

ITGA6 LAMB3

6.78e-0531412DOID:0060737 (implicated_via_orthology)
Diseasemetal metabolism disorder (implicated_via_orthology)

ATP7A ATP7B

1.35e-0441412DOID:896 (implicated_via_orthology)
DiseaseLiver Failure, Acute

ATP7B CAST ALDOB

2.01e-04241413C0162557
DiseaseWilson disease (implicated_via_orthology)

ATP7A ATP7B

2.25e-0451412DOID:893 (implicated_via_orthology)
DiseaseMenkes disease (implicated_via_orthology)

ATP7A ATP7B

2.25e-0451412DOID:1838 (implicated_via_orthology)
Diseasejunctional epidermolysis bullosa (is_implicated_in)

ITGA6 LAMB3

4.69e-0471412DOID:3209 (is_implicated_in)
DiseaseParkinson's disease (is_implicated_in)

CAST DBH DNAJC6 PPARGC1A

4.91e-04761414DOID:14330 (is_implicated_in)
Diseasedilated cardiomyopathy (implicated_via_orthology)

CENPF DICER1 PPARGC1A DMD

5.96e-04801414DOID:12930 (implicated_via_orthology)
Diseasespinal muscular atrophy (implicated_via_orthology)

ATP7A ATP7B

7.98e-0491412DOID:12377 (implicated_via_orthology)
Diseasemean corpuscular hemoglobin concentration

ATP7B GATAD2A ANP32B HECTD4 SRPK1 PFAS LCP1 ITPR2 LUC7L HECW2 ATAD2B PDIA2 MACF1 VPS13B

8.60e-04110514114EFO_0004528
DiseaseParkinson's disease (implicated_via_orthology)

HDAC6 HTRA4 DNAJC6 PPARGC1A FOXO4

9.67e-041571415DOID:14330 (implicated_via_orthology)
Diseaselevel of Triacylglycerol (51:3) in blood serum

GATAD2A LCP1

9.95e-04101412OBA_2045163
DiseaseCystic Kidney Diseases

FAT4 UMOD

1.21e-03111412C1691228
DiseaseRetinitis Pigmentosa

RBP3 ARHGEF18 PCARE ZNF513

1.59e-031041414C0035334
Diseaseamyotrophic lateral sclerosis (biomarker_via_orthology)

RARA CASP12

1.71e-03131412DOID:332 (biomarker_via_orthology)
Diseasecomplex trait

EPHB4 GATAD2A ZNF507 EMILIN3 HHIP MACF1

1.98e-032711416EFO_0010578
Diseasetetralogy of Fallot (implicated_via_orthology)

BMP10 DNAH5

1.99e-03141412DOID:6419 (implicated_via_orthology)
Diseasesusceptibility to bacterial meningitis measurement

CYB5R4 DNAH5 SDC4

1.99e-03521413EFO_0008411
DiseaseColorectal Neoplasms

ATP7B CNPPD1 HHIP FBLN2 KDM2A SESN2

2.21e-032771416C0009404
DiseaseAlzheimer's disease (biomarker_via_orthology)

ATP7A CASP12 LRP1

2.72e-03581413DOID:10652 (biomarker_via_orthology)
Diseasesleep duration, high density lipoprotein cholesterol measurement

CARMIL2 LCP1 MACF1 DOCK6

2.76e-031211414EFO_0004612, EFO_0005271
Diseasevelopharyngeal dysfunction

ITPR2 SLC28A1 UMOD SDC4

2.84e-031221414EFO_0009336
DiseaseHypertriglyceridemia

LAMC1 LCP1

3.68e-03191412EFO_0004211
Diseasebody surface area

DICER1 DDX6 HHIP FBLN2 NRXN3 ATXN3 MACF1 KDM2A AFG1L

3.85e-036431419EFO_0022196
DiseaseSeizures

TREX1 ATP7A GLDC MACF1 ALPL

4.03e-032181415C0036572
DiseaseParkinson's disease (is_marker_for)

CAST DBH PPARGC1A

4.09e-03671413DOID:14330 (is_marker_for)
Diseasereticulocyte measurement

GATAD2A ANP32B HECTD4 PFAS LCP1 KANK2 PLEK2 LUC7L SLFN12L ATAD2B ATP11A AFG1L

4.73e-03105314112EFO_0010700

Protein segments in the cluster

PeptideGeneStartEntry
EGLSMQLGQREAEAT

USHBP1

326

Q8N6Y0
GGTNLRDDIMRLDDT

DDX6

201

P26196
GGLFVMDEDATLQDL

AKT1S1

126

Q96B36
SMEDLSLDLGALQGS

ARHGEF18

16

Q6ZSZ5
GTELGLNAEEMENLS

GRAMD1C

196

Q8IYS0
LSGGMSEEDATLNLN

ALDOB

271

P05062
LEGNTMADESLITGE

ATP7B

846

P35670
SLAGNLLDDRGMTAL

CARMIL2

281

Q6F5E8
MGAQASQDLGDELLD

CD248

356

Q9HCU0
ELLMLRATDGDLGDN

FAT4

601

Q6V0I7
SLLVRADDGLQSSDM

FAT4

1811

Q6V0I7
LMDDLGLSQDSAEGL

AFG1L

431

Q8WV93
LELGDSLMRLGAEND

ANKIB1

916

Q9P2G1
ASEQGDSMLGDLLDS

ACVRL1

166

P37023
DSMLGDLLDSDCTTG

ACVRL1

171

P37023
LSENRIFGGLDMLAE

ANP32B

71

Q92688
SMGSLGQREDLQDED

ATP8B3

86

O60423
RQAEGLSEDGAAMAV

DMD

1931

P11532
RDESDDGGVAQRMAL

CEP170B

616

Q9Y4F5
ASDGFNLERLEMLGD

DICER1

1306

Q9UPY3
GSELDLLGMRDLLEN

CASP12

116

Q6UXS9
LEDLMRDGSDGAALL

CAMSAP1

241

Q5T5Y3
DLASRLSSDEGEMDG

ATXN7L1

431

Q9ULK2
LRGAIEDMGFDATLS

ATP7A

431

Q04656
VGNADFSDMRLLDGD

CPNE6

471

O95741
QEMLENSEGLDTLSG

RARA

411

P10276
ANALALAMERDGSSG

PSMB6

191

P28072
GEGSMLRLEDLGDQR

ITPR2

531

Q14571
SLEEEGGLIMFSRAS

HECW2

481

Q9P2P5
MERGLLASDLNTDGD

GATAD2A

31

Q86YP4
SLLAGTADGSLRMDD

M1AP

271

Q8TC57
LDQLMGTARDGDETR

LUC7L

11

Q9NQ29
MENGALDSFLRLNDG

EPHB4

696

P54760
LENLEAGADDINGLM

DST

3946

Q03001
AATGSRGELMLEANS

KIF12

271

Q96FN5
RQDLGMESTSLDDVL

LRRC75A

81

Q8NAA5
LDGSGLEVIDAMRSQ

LRP1

1771

Q07954
VSTLLALMDGLDNRG

ATAD2B

526

Q9ULI0
RVLEANDGSGMLDED

ATXN3

211

P54252
QENGMATRLDEGLED

CARMIL3

1001

Q8ND23
DDLSTGGRLQNMTVD

TMEM63C

6

Q9P1W3
EMAGREALSLGTEAE

FBLN2

581

P98095
NLMATGDLDQDGRIS

LCP1

56

P13796
IISDLMDEGEGLDFN

FOXO4

486

P98177
MSDGDILGKSLRTDD

NAV3

821

Q8IVL0
NEDLRSGLSSALGEM

CSPP1

511

Q1MSJ5
RESNGTMADLGNIAD

ABCC11

841

Q96J66
ALGMAGSRELKDSDL

NRDE2

806

Q9H7Z3
ESADTLRLELDGGQM

NRXN2

776

Q9P2S2
TASGESEILDLEGDM

NRXN3

566

Q9Y4C0
ASLDSMLGGLEQELQ

LPXN

126

O60711
MELDSEEALGTRTEG

ANKRD65

21

E5RJM6
VLSQNLRIEDDMDGG

ITGA6

156

P23229
MRLEDEAAAQALIGG

PDIA2

156

Q13087
LIGLSSLDGEDELME

HECTD4

3191

Q9Y4D8
EMSSGDLDLRLGFDL

PLA2G4F

306

Q68DD2
EDELAMRGFLQEGDL

EXOSC2

126

Q13868
DSLIQDALDGLMLEG

EXOC7

396

Q9UPT5
GLSRDMQGLSLDAAS

MVB12A

161

Q96EY5
ELDGMGAIGRDTDSL

MACF1

5146

Q9UPN3
GDDASSLRSRLEAMN

MACF1

6296

Q9UPN3
INSGLAMDGLFDDSE

PPARGC1A

501

Q9UBK2
EAVEMDRAIGQAGSL

ALPL

351

P05186
SALAGMQDLRLEGAL

RBBP8NL

341

Q8NC74
VEGGLSDALRTEENM

BOD1L1

2091

Q8NFC6
MDLTGLLLDEEGTFS

CNPPD1

1

Q9BV87
DSDSLSMAVLRGKDN

HTRA4

451

P83105
GRGQVMSSLAELEDD

IL32

81

P24001
DAVMSDGNLETRLGS

HEATR5A

391

Q86XA9
MDLELNGLESGNGDE

KDM2A

361

Q9Y2K7
DNEGERNMLVLVSGE

BMP10

176

O95393
RLASMLDSDTEGEGD

DOCK6

1191

Q96HP0
EQTGDMSLLSNLEGA

CENPF

1501

P49454
GLDKLLASEGSTMDE

CHD1L

521

Q86WJ1
DMDVLTTLSLGDRAA

COL6A2

981

P12110
LFGMSDRGELENADL

DBH

86

P09172
DVDLLGLEGSAMSNS

DNAJC6

496

O75061
MAEVGEDSGARALLA

FOXK1

1

P85037
SGMDAALDDLIDTLG

CAST

151

P20810
GASGSNTEEEIRMEL

KANK2

576

Q63ZY3
LTDRDGSTALMVALD

KANK2

801

Q63ZY3
MADGNEDLRADDLPG

KLHDC2

1

Q9Y2U9
LSDKDDMGRRNAGID

KIAA1210

611

Q9ULL0
DLESLDRSFNGLLTM

LAMB3

681

Q13751
ELESLIANLGTGDEM

LAMC1

1051

P11047
AGDELTRLSAAMLEG

EMILIN3

416

Q9NT22
LQGMDLNLEAEALAG

HDAC6

71

Q9UBN7
SGSGDLDDLEDSMIG

SDC4

61

P31431
SLGEEMREDGLSPNE

S100PBP

176

Q96BU1
DGSGMKREATADDLI

DDB1

1116

Q16531
SELRDGSLNDGGNMA

MYBL1

461

P10243
NMLDAADGGLLNSVR

DNAH5

151

Q8TE73
RLDLSGNALTEDMAA

NRROS

136

Q86YC3
GNTIMRLDDSVFEGL

NRROS

166

Q86YC3
TESLRMLGDSKDAGA

PCARE

741

A6NGG8
LDQLMGTSRDGDTTR

LUC7L2

11

Q9Y383
RLSSDDFLGTLEMNL

FER1L6

1701

Q2WGJ9
RDGEILASGSMDNTV

TAF5

721

Q15542
GLEALMSSGRVDNLA

SESN2

66

P58004
MLAQEAGSALGSDVD

SOHLH1

286

Q5JUK2
EDRMDELGAGIAQSR

TRIM47

236

Q96LD4
EGEAAMLGRSQGDLR

TRIM47

291

Q96LD4
ELMRDVEAATGQDLG

UVSSA

626

Q2YD98
DNDSDLALGMLAGAA

PLEKHB2

196

Q96CS7
GELDLSMTNLRGAEG

TMEM200C

416

A6NKL6
TLLDKDDMGDEQRGS

RFX2

681

P48378
ADGMRLALADAGDTV

LARS1

736

Q9P2J5
EKLSRDGAFLMDAGS

SEC24A

976

O95486
EALLQGEEEMGLTSS

MTF1

736

Q14872
GNLQMSDRQLDEAGE

HIP1

161

O00291
LVESSFSGEMLEDLG

SHPRH

176

Q149N8
SLDEDNDRLMVRSGG

SEZ6L2

396

Q6UXD5
TLMERDTEGGAAEIN

SRPK1

341

Q96SB4
LDMTEEELGASGDLS

STARD9

4156

Q9P2P6
LMRAAGSDGTELFDQ

CYB5R4

96

Q7L1T6
ERMEAGLSELSGSVA

PEX14

146

O75381
EMDGLSDFTGSVLRL

HHIP

381

Q96QV1
SMDSEGGSLLLDEDS

PDLIM2

206

Q96JY6
MSDSDLGEDEGLLSL

TGIF2

1

Q9GZN2
EFDLNGNGDIDIMSL

AIF1

56

P55008
LTRDNLSGLSADMQD

ATP11A

741

P98196
QLMGFERDSEGDSLG

ZNF513

61

Q8N8E2
MGAIRSGDLAEQFLD

PLEK2

201

Q9NYT0
RDSGGETESMLLNET

WDR48

531

Q8TAF3
LAEILGADLQMLSGD

RBP3

981

P10745
LDGGDLSRFALLMTN

UMOD

491

P07911
DGIGLDLENSFSNML

SLFN12L

91

Q6IEE8
FALSALVGEDGRLDM

RHBG

266

Q9H310
NSLLAGGDDDTMSVI

STAG2

1046

Q8N3U4
GAGEDMDESSLLDLL

SH3RF3

41

Q8TEJ3
RFGLTEAGDLSAEDM

ARHGAP28

326

Q9P2N2
AILREEGSNGDREMA

PFAS

1066

O15067
MAEGGAADLDTQRSD

USP15

1

Q9Y4E8
LENMGADFLESLEEG

SLC28A1

21

O00337
GLMKDDRAESQASSL

ZEB1

1091

P37275
LSLTEAQIGREGMDD

ZNF507

426

Q8TCN5
LLEKMSSERDGLGSD

ZNF543

146

Q08ER8
DMLGNITGSEDETRI

VPS13B

306

Q7Z7G8
GLLALDNGEMEVLES

TEX15

721

Q9BXT5
RSLGGDEGLDITQDM

GINS1

126

Q14691
AELAMLGLTSALDGA

TREX1

136

Q9NSU2
MADEALAGLDEGALR

SMTN

1

P53814
ANMNGLLDSDGDSLS

PPIP5K1

611

Q6PFW1
SLSLGEVLDGDRMAE

TM9SF1

76

O15321
SVSEGSAELLMEGER

VWA5B1

506

Q5TIE3
ITGLDMANASLLDEG

GLDC

186

P23378
ELELMELNSSSGGEG

KCNF1

426

Q9H3M0
QLEMLSGDGVRLDSE

KRT72

186

Q14CN4
GSGMGDEENTSRRLL

MXRA5

701

Q9NR99