Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmyosin light chain binding

MYO19 SPATA6

2.66e-058202GO:0032027
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

SOX17 SOX2 KMT2D EHF ZIC2

1.86e-04560205GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

SOX17 SOX2 KMT2D EHF ZIC2

1.96e-04566205GO:0001216
GeneOntologyMolecularFunctionchromatin binding

SOX2 EP400 STAG2 CRTC2 ZIC2

6.68e-04739205GO:0003682
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

TRERF1 SOX17 SOX2 CRTC2

2.39e-03582204GO:0140297
GeneOntologyMolecularFunctionmyosin binding

MYO19 SPATA6

3.24e-0385202GO:0017022
GeneOntologyBiologicalProcessendocardial cell differentiation

SOX17 NRG1

1.34e-056202GO:0060956
GeneOntologyBiologicalProcesscardiac endothelial cell differentiation

SOX17 NRG1

2.49e-058202GO:0003348
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

TRERF1 SOX17 MEPCE SOX2 KMT2D CRTC2 EHF ZIC2

2.52e-051390208GO:0045944
GeneOntologyBiologicalProcessendodermal cell fate specification

SOX17 SOX2

4.89e-0511202GO:0001714
GeneOntologyBiologicalProcessendocardium development

SOX17 NRG1

6.92e-0513202GO:0003157
GeneOntologyBiologicalProcessendodermal cell fate commitment

SOX17 SOX2

1.35e-0418202GO:0001711
GeneOntologyBiologicalProcessglial cell fate commitment

SOX2 NRG1

1.51e-0419202GO:0021781
GeneOntologyBiologicalProcessstem cell differentiation

SOX17 SOX2 NRG1 ZIC2

1.91e-04306204GO:0048863
HumanPhenoAlobar holoprosencephaly

STAG2 KMT2D ZIC2

1.33e-07973HP:0006988
HumanPhenoHoloprosencephaly

SOX2 STAG2 KMT2D ZIC2

1.91e-068074HP:0001360
HumanPhenoButterfly vertebrae

SOX2 STAG2 KMT2D

2.09e-062173HP:0003316
HumanPhenoProboscis

STAG2 KMT2D ZIC2

2.09e-062173HP:0012806
HumanPhenoVertebral clefting

SOX2 STAG2 KMT2D

1.66e-054173HP:0008428
HumanPhenoExpressive language delay

STAG2 KMT2D ZIC2

4.27e-055673HP:0002474
HumanPhenoMedian cleft palate

STAG2 KMT2D ZIC2

4.27e-055673HP:0009099
HumanPhenoMedian cleft upper lip

STAG2 KMT2D ZIC2

4.27e-055673HP:0000161
HumanPhenoLanguage delay

STAG2 KMT2D ZIC2

4.27e-055673HP:0002336
HumanPhenoMedian cleft lip and palate

STAG2 KMT2D ZIC2

4.27e-055673HP:0008501
HumanPhenoSemilobar holoprosencephaly

STAG2 ZIC2

5.80e-05972HP:0002507
HumanPhenoHemivertebrae

SOX2 STAG2 KMT2D

5.81e-056273HP:0002937
HumanPhenoDiabetes insipidus

SOX2 STAG2 ZIC2

6.39e-056473HP:0000873
HumanPhenoAbnormality of the hypothalamus

SOX2 STAG2 ZIC2

9.88e-057473HP:0002443
HumanPhenoGastrointestinal atresia

SOX2 STAG2 ZIC2

1.96e-049373HP:0002589
HumanPhenoAspiration pneumonia

STAG2 KMT2D ZIC2

2.08e-049573HP:0011951
HumanPhenoOptic nerve hypoplasia

SOX2 STAG2 KMT2D

2.97e-0410773HP:0000609
HumanPhenoAplasia of the falx cerebri

STAG2 ZIC2

3.04e-042072HP:0010654
HumanPhenoSepto-optic dysplasia

SOX2 STAG2

3.04e-042072HP:0100842
HumanPhenoAbnormal septum pellucidum morphology

SOX2 STAG2 ZIC2

3.40e-0411273HP:0007375
HumanPhenoCyclopia

STAG2 ZIC2

3.69e-042272HP:0009914
HumanPhenoSingle naris

STAG2 ZIC2

3.69e-042272HP:0009932
HumanPhenoUreteropelvic junction obstruction

SOX17 KMT2D

4.04e-042372HP:0000074
HumanPhenoDuplicated collecting system

SOX17 KMT2D

4.40e-042472HP:0000081
HumanPhenoAplasia/Hypoplasia of the nares

STAG2 ZIC2

4.40e-042472HP:0100597
HumanPhenoGrowth hormone and pituitary abnormality

SOX2 STAG2 KMT2D ZIC2

4.54e-0431974HP:0000844
HumanPhenoAbnormality of the pituitary gland

SOX2 STAG2 KMT2D ZIC2

4.54e-0431974HP:0000838
HumanPhenoAbnormal heart rate variability

STAG2 ZIC2

4.78e-042572HP:0031860
HumanPhenoAbnormal diencephalon morphology

SOX2 STAG2 ZIC2

5.16e-0412973HP:0010662
HumanPhenoAbnormal lateral ventricle morphology

STAG2 KMT2D ZIC2

5.16e-0412973HP:0030047
HumanPhenoLobar holoprosencephaly

KMT2D ZIC2

5.18e-042672HP:0006870
HumanPhenoDepressed nasal ridge

STAG2 KMT2D ZIC2

5.39e-0413173HP:0000457
HumanPhenoAbnormality of the falx cerebri

STAG2 ZIC2

5.59e-042772HP:0010653
HumanPhenoSingle central incisor

STAG2 ZIC2

5.59e-042772HP:0001573
HumanPhenoSolitary median maxillary central incisor

STAG2 ZIC2

5.59e-042772HP:0006315
HumanPhenoOromotor apraxia

STAG2 ZIC2

6.02e-042872HP:0007301
HumanPhenoAbnormal dura mater morphology

STAG2 ZIC2

6.02e-042872HP:0010652
HumanPhenoDecreased response to growth hormone stimulation test

STAG2 KMT2D ZIC2

6.02e-0413673HP:0000824
HumanPhenoAbnormal renal collecting system morphology

SOX17 KMT2D

6.91e-043072HP:0004742
HumanPhenoPanhypopituitarism

STAG2 ZIC2

7.39e-043172HP:0000871
HumanPhenoHypotelorism

STAG2 KMT2D ZIC2

7.42e-0414673HP:0000601
HumanPhenoAbnormality of the anterior pituitary

SOX2 STAG2 KMT2D ZIC2

7.71e-0436674HP:0011747
HumanPhenoCoarctation of aorta

STAG2 KMT2D ZIC2

8.03e-0415073HP:0001680
HumanPhenoUreteral stenosis

SOX17 KMT2D

8.38e-043372HP:0000071
HumanPhenoAbnormal response to endocrine stimulation test

STAG2 KMT2D ZIC2

8.51e-0415373HP:0031073
HumanPhenoAbnormal growth hormone level

STAG2 KMT2D ZIC2

8.67e-0415473HP:0032367
HumanPhenoAbnormal endocrine physiology

STAG2 KMT2D ZIC2

9.01e-0415673HP:0031072
HumanPhenoAbnormal pituitary gland morphology

SOX2 STAG2 KMT2D ZIC2

9.73e-0438974HP:0012503
HumanPhenoAbnormal morphology of the olfactory bulb

STAG2 ZIC2

9.97e-043672HP:0040327
HumanPhenoVertebral segmentation defect

SOX2 STAG2 KMT2D

1.01e-0316273HP:0003422
HumanPhenoBifid uvula

STAG2 KMT2D ZIC2

1.10e-0316773HP:0000193
HumanPhenoUreteral obstruction

SOX17 KMT2D

1.17e-033972HP:0006000
HumanPhenoHydrocephalus

SOX2 STAG2 KMT2D ZIC2

1.32e-0342174HP:0000238
HumanPhenoCentral apnea

STAG2 ZIC2

1.36e-034272HP:0002871
HumanPhenoChronic lung disease

STAG2 ZIC2

1.36e-034272HP:0006528
HumanPhenoAnterior hypopituitarism

STAG2 KMT2D ZIC2

1.41e-0318273HP:0000830
HumanPhenoTemperature instability

STAG2 ZIC2

1.42e-034372HP:0005968
HumanPhenoIris coloboma

SOX2 KMT2D ZIC2

1.43e-0318373HP:0000612
HumanPhenoCleft upper lip

STAG2 KMT2D ZIC2

1.43e-0318373HP:0000204
HumanPhenoSloping forehead

STAG2 ZIC2 TUBGCP4

1.55e-0318873HP:0000340
HumanPhenoDuodenal atresia

STAG2 ZIC2

1.56e-034572HP:0002247
HumanPhenoSleep-wake cycle disturbance

STAG2 ZIC2

1.56e-034572HP:0006979
HumanPhenoMaternal diabetes

SOX2 ZIC2

1.56e-034572HP:0009800
HumanPhenoHypopituitarism

STAG2 KMT2D ZIC2

1.62e-0319173HP:0040075
HumanPhenoAbnormality of the hypothalamus-pituitary axis

SOX2 STAG2 KMT2D ZIC2

1.68e-0344974HP:0000864
HumanPhenoInfantile axial hypotonia

STAG2 ZIC2

1.77e-034872HP:0009062
HumanPhenoAbnormal uvula morphology

STAG2 KMT2D ZIC2

1.78e-0319773HP:0000172
HumanPhenoHypoplastic left heart

STAG2 KMT2D

1.85e-034972HP:0004383
HumanPhenoCongenital malformation of the left heart

STAG2 KMT2D

2.00e-035172HP:0045017
HumanPhenoConstipation

SOX17 SOX2 STAG2 ZIC2

2.03e-0347274HP:0002019
HumanPhenoAbnormal hypothalamus physiology

STAG2 ZIC2

2.16e-035372HP:0012285
HumanPhenoAbnormal vertebral morphology

SOX2 STAG2 KMT2D ZIC2

2.21e-0348374HP:0003468
HumanPhenoHypoplastic heart

STAG2 KMT2D

2.24e-035472HP:0001961
HumanPhenoInfantile muscular hypotonia

STAG2 KMT2D ZIC2

2.41e-0321973HP:0008947
HumanPhenoAtresia of the external auditory canal

STAG2 KMT2D

2.58e-035872HP:0000413
HumanPhenoPreauricular pit

STAG2 KMT2D

2.85e-036172HP:0004467
HumanPhenoAbnormal intestine morphology

SOX17 SOX2 STAG2 KMT2D TNFAIP3 ZIC2

2.90e-03145976HP:0002242
HumanPhenoAbnormal number of incisors

STAG2 ZIC2

3.04e-036372HP:0011064
HumanPhenoCleft soft palate

STAG2 KMT2D ZIC2

3.06e-0323873HP:0000185
HumanPhenoCongenital malformation of the great arteries

SOX2 STAG2 KMT2D ZIC2

3.11e-0352974HP:0011603
HumanPhenoCleft secondary palate

STAG2 KMT2D ZIC2

3.14e-0324073HP:0410004
HumanPhenoCleft lip

STAG2 KMT2D ZIC2

3.14e-0324073HP:0410030
HumanPhenoUreteral duplication

SOX17 KMT2D

3.43e-036772HP:0000073
HumanPhenoIntestinal atresia

STAG2 ZIC2

3.43e-036772HP:0011100
HumanPhenoPeriauricular skin pits

STAG2 KMT2D

3.43e-036772HP:0100277
HumanPhenoAnteriorly placed anus

KMT2D ZIC2

3.53e-036872HP:0001545
HumanPhenoAbnormal uvea morphology

SOX2 KMT2D TNFAIP3 ZIC2 TUBGCP4

3.61e-0396575HP:0000553
HumanPhenoRenal duplication

SOX17 KMT2D

3.63e-036972HP:0000075
HumanPhenoAbsent septum pellucidum

SOX2 STAG2

3.63e-036972HP:0001331
HumanPhenoAbdominal organ duplication

SOX17 KMT2D

3.63e-036972HP:0005217
DomainHMG_box

SOX17 SOX2 KMT2D

2.38e-0553203PF00505
DomainHMG

SOX17 SOX2 KMT2D

2.52e-0554203SM00398
Domain-

SOX17 SOX2 KMT2D

2.66e-05552031.10.30.10
DomainHMG_box_dom

SOX17 SOX2 KMT2D

4.40e-0565203IPR009071
DomainMYB_LIKE

TRERF1 EP400

7.48e-0438202PS50090
DomainSANT

TRERF1 EP400

1.29e-0350202SM00717
DomainSANT/Myb

TRERF1 EP400

1.40e-0352202IPR001005
DomainHMG_BOX_2

SOX17 SOX2

1.51e-0354202PS50118
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

SOX17 SOX2 KMT2D

1.34e-0542163M27272
PathwayWP_MESODERMAL_COMMITMENT_PATHWAY

TRERF1 SOX17 SOX2 ZIC2

2.19e-05153164M39546
PathwayWP_CARDIAC_PROGENITOR_DIFFERENTIATION

SOX17 SOX2 NRG1

2.71e-0553163M39681
PathwayREACTOME_FORMATION_OF_THE_ANTERIOR_NEURAL_PLATE

SOX2 ZIC2

6.60e-0511162M48031
PathwayWP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY

SOX2 EP400 KMT2D ZIC2

3.03e-04301164MM15983
PathwayREACTOME_GASTRULATION

SOX17 SOX2 ZIC2

3.84e-04129163M46433
PathwayWP_ENDODERM_DIFFERENTIATION

TRERF1 SOX17 SOX2

5.20e-04143163M39591
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

SOX2 EP400 STAG2 KMT2D

1.42e-078320428794006
Pubmed

Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies.

NRG1 DLGAP1 TNFAIP3

2.49e-072220323247143
Pubmed

Foxp1 coordinates cardiomyocyte proliferation through both cell-autonomous and nonautonomous mechanisms.

SOX17 SOX2 NRG1

2.86e-072320320713518
Pubmed

Unique and redundant roles of SOX2 and SOX17 in regulating the germ cell tumor fate.

SOX17 SOX2

3.14e-07220231583686
Pubmed

Sox2 gene regulation via the D1 enhancer in embryonic neural tube and neural crest by the combined action of SOX2 and ZIC2.

SOX2 ZIC2

3.14e-07220231997540
Pubmed

Holoprosencephaly Overview

STAG2 KMT2D ZIC2

3.71e-072520320301702
Pubmed

Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells.

SOX17 SOX2 ZIC2

4.19e-072620322992956
Pubmed

A census of human transcription factors: function, expression and evolution.

TRERF1 SOX17 SOX2 RC3H2 KMT2D EHF ZIC2

4.65e-0790820719274049
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

TRERF1 MEPCE SOX2 EP400 AMOTL2

4.75e-0728220523667531
Pubmed

The SOX17/miR-371-5p/SOX2 axis inhibits EMT, stem cell properties and metastasis in colorectal cancer.

SOX17 SOX2

9.42e-07320225868860
Pubmed

Mechanism and Role of SOX2 Repression in Seminoma: Relevance to Human Germline Specification.

SOX17 SOX2

9.42e-07320227132888
Pubmed

The structure of Sox17 bound to DNA reveals a conserved bending topology but selective protein interaction platforms.

SOX17 SOX2

9.42e-07320219328208
Pubmed

MLL4 Regulates the Progression of Non-Small-Cell Lung Cancer by Regulating the PI3K/AKT/SOX2 Axis.

SOX2 KMT2D

1.88e-06420236701842
Pubmed

Neuregulin1 and ErbB expression in the uninjured and regenerating olfactory mucosa.

SOX2 NRG1

1.88e-06420226474499
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

TRERF1 SOX2 EP400 ZIC2 TUBGCP4

2.51e-0639620526687479
Pubmed

G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst.

SOX17 SOX2

3.14e-06520229745895
Pubmed

Neural tube closure depends on expression of Grainyhead-like 3 in multiple tissues.

SOX17 SOX2

3.14e-06520229397878
Pubmed

Interplay of Oct4 with Sox2 and Sox17: a molecular switch from stem cell pluripotency to specifying a cardiac fate.

SOX17 SOX2

3.14e-06520219736317
Pubmed

SOX7 and GATA-4 are competitive activators of Fgf-3 transcription.

SOX17 SOX2

4.71e-06620215082719
Pubmed

Plakoglobin is a mechanoresponsive regulator of naive pluripotency.

SOX17 SOX2

4.71e-06620237419903
Pubmed

Mapping the distribution of stem/progenitor cells across the mouse middle ear during homeostasis and inflammation.

SOX17 SOX2

4.71e-06620229217752
Pubmed

Zic2 is expressed in pluripotent cells in the blastocyst and adult brain expression overlaps with makers of neurogenesis.

SOX2 ZIC2

6.59e-06720218755297
Pubmed

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells.

SOX17 SOX2

6.59e-06720217875931
Pubmed

Dominant and context-specific control of endodermal organ allocation by Ptf1a.

SOX17 SOX2

8.78e-06820225371369
Pubmed

Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm.

SOX17 SOX2

8.78e-06820223474895
Pubmed

Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors.

SOX2 KMT2D

1.13e-05920226691508
Pubmed

Lima1 mediates the pluripotency control of membrane dynamics and cellular metabolism.

SOX17 SOX2

1.41e-051020235105859
Pubmed

MicroRNA-127 Promotes Mesendoderm Differentiation of Mouse Embryonic Stem Cells by Targeting Left-Right Determination Factor 2.

SOX17 SOX2

1.41e-051020227072135
Pubmed

Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal.

SOX17 SOX2

1.41e-051020220123909
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

TRERF1 MEPCE EP400 KMT2D

1.52e-0526820433640491
Pubmed

The Zic2 gene directs the formation and function of node cilia to control cardiac situs.

SOX17 ZIC2

2.07e-051220224585447
Pubmed

Morphogenetic analysis of peri-implantation development.

SOX17 SOX2

2.07e-051220223728800
Pubmed

TMEM132A regulates mouse hindgut morphogenesis and caudal development.

SOX17 SOX2

2.44e-051320237390294
Pubmed

Deciphering the Sox-Oct partner code by quantitative cooperativity measurements.

SOX17 SOX2

2.44e-051320222344693
Pubmed

The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.

EP400 KMT2D

2.44e-051320216510874
Pubmed

Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families.

SOX17 SOX2

2.44e-051320212194848
Pubmed

A Sprouty4 reporter to monitor FGF/ERK signaling activity in ESCs and mice.

SOX17 SOX2

2.44e-051320229964027
Pubmed

Oct4 cell-autonomously promotes primitive endoderm development in the mouse blastocyst.

SOX17 SOX2

2.44e-051320223747191
Pubmed

Numerous members of the Sox family of HMG box-containing genes are expressed in developing mouse teeth.

SOX17 SOX2

2.85e-05142028921394
Pubmed

Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program.

EP400 KMT2D

3.28e-051520216510875
Pubmed

No evidence of involvement of E-cadherin in cell fate specification or the segregation of Epi and PrE in mouse blastocysts.

SOX17 SOX2

3.28e-051520230735538
Pubmed

GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst.

SOX17 SOX2

3.28e-051520224835466
Pubmed

Dominant-negative Sox18 function inhibits dermal papilla maturation and differentiation in all murine hair types.

SOX17 SOX2

3.28e-051520228512199
Pubmed

Endocardium differentiation through Sox17 expression in endocardium precursor cells regulates heart development in mice.

SOX17 NRG1

3.28e-051520231420575
Pubmed

Pluripotency factors regulate definitive endoderm specification through eomesodermin.

SOX17 SOX2

3.75e-051620221245162
Pubmed

The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos.

SOX17 SOX2

3.75e-051620233929320
Pubmed

Dual lineage-specific expression of Sox17 during mouse embryogenesis.

SOX17 SOX2

3.75e-051620222865702
Pubmed

Redundant roles of Tead1 and Tead2 in notochord development and the regulation of cell proliferation and survival.

SOX17 SOX2

3.75e-051620218332127
Pubmed

A balanced Oct4 interactome is crucial for maintaining pluripotency.

SOX17 SOX2

3.75e-051620235171666
Pubmed

Hindgut defects and transformation of the gastro-intestinal tract in Tcf4(-/-)/Tcf1(-/-) embryos.

SOX17 SOX2

3.75e-051620215057272
Pubmed

Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2.

SOX17 SOX2

4.25e-051720231171776
Pubmed

Spatio-temporal expression of Sox genes in murine palatogenesis.

SOX17 SOX2

4.25e-051720227241892
Pubmed

Impaired motor coordination and disrupted cerebellar architecture in Fgfr1 and Fgfr2 double knockout mice.

SOX2 ZIC2

4.25e-051720222578469
Pubmed

Oct4 regulates the embryonic axis and coordinates exit from pluripotency and germ layer specification in the mouse embryo.

SOX17 SOX2

4.25e-051720229915126
Pubmed

Ipsilateral and Contralateral Retinal Ganglion Cells Express Distinct Genes during Decussation at the Optic Chiasm.

SOX2 ZIC2

4.78e-051820227957530
Pubmed

Expression of Sox genes in tooth development.

SOX17 SOX2

4.78e-051820226864488
Pubmed

Neurog3-dependent pancreas dysgenesis causes ectopic pancreas in Hes1 mutant mice.

SOX17 SOX2

4.78e-051820230093553
Pubmed

Cell-Intrinsic Control of Interneuron Migration Drives Cortical Morphogenesis.

SOX2 NRG1

5.34e-051920229474907
Pubmed

Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs.

SOX17 SOX2

5.34e-051920235988542
Pubmed

ASPP2 maintains the integrity of mechanically stressed pseudostratified epithelia during morphogenesis.

SOX17 SOX2

5.34e-051920235177595
Pubmed

HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst.

SOX17 SOX2

5.93e-052020225340657
Pubmed

Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning.

SOX17 SOX2

5.93e-052020229412136
Pubmed

Wntless is required for peripheral lung differentiation and pulmonary vascular development.

SOX17 SOX2

5.93e-052020223523683
Pubmed

Developmental SHP2 dysfunction underlies cardiac hypertrophy in Noonan syndrome with multiple lentigines.

SOX17 NRG1

6.55e-052120227348588
Pubmed

Expression of Sox transcription factors in the developing mouse pancreas.

SOX17 SOX2

6.55e-052120212815626
Pubmed

Schwann cell myelination requires integration of laminin activities.

SOX2 NRG1

6.55e-052120222767514
Pubmed

Characterization of a common progenitor pool of the epicardium and myocardium.

SOX17 SOX2

6.55e-052120233414188
Pubmed

Embryo model completes gastrulation to neurulation and organogenesis.

SOX17 SOX2

7.21e-052220236007540
Pubmed

Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS.

SOX2 ZIC2

7.89e-052320224360543
Pubmed

Rap1 controls epiblast morphogenesis in sync with the pluripotency states transition.

SOX17 SOX2

7.89e-052320235998584
Pubmed

cDNAs with long CAG trinucleotide repeats from human brain.

EP400 KMT2D

7.89e-05232029225980
Pubmed

Analyzing embryo dormancy at single-cell resolution reveals dynamic transcriptional responses and activation of integrin-Yap/Taz prosurvival signaling.

SOX17 SOX2

8.61e-052420239047740
Pubmed

Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse.

SOX17 SOX2

9.35e-052520219786569
Pubmed

A cluster of three long-range enhancers directs regional Shh expression in the epithelial linings.

SOX17 SOX2

9.35e-052520219369396
Pubmed

Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development.

SOX17 SOX2

9.35e-052520236046192
Pubmed

LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli.

SOX2 ZIC2

1.01e-042620226439398
Pubmed

The RNA helicase DDX6 controls early mouse embryogenesis by repressing aberrant inhibition of BMP signaling through miRNA-mediated gene silencing.

SOX17 SOX2

1.09e-042720236197846
Pubmed

A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.

TNFAIP3 EHF

1.09e-042720223740937
Pubmed

Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis.

SOX2 ZIC2

1.09e-042720229386106
Pubmed

Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neurons.

SOX2 ZIC2

1.09e-042720233760820
Pubmed

Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency.

SOX17 SOX2

1.09e-042720227586544
Pubmed

An Oct4-centered protein interaction network in embryonic stem cells.

SOX2 EP400 KMT2D

1.17e-0416720320362541
Pubmed

Mediator and cohesin connect gene expression and chromatin architecture.

SOX2 STAG2

1.18e-042820220720539
Pubmed

EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition.

SOX17 SOX2

1.26e-042920218794329
Pubmed

The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap.

SOX2 ZIC2

1.26e-042920225336744
Pubmed

Activation of Wnt signaling reduces ipsilaterally projecting retinal ganglion cells in pigmented retina.

SOX2 ZIC2

1.45e-043120230254141
Pubmed

Lats1/2 inactivation reveals Hippo function in alveolar type I cell differentiation during lung transition to air breathing.

SOX2 AMOTL2

1.45e-043120230305289
Pubmed

Specific functions for ERK/MAPK signaling during PNS development.

SOX2 NRG1

1.45e-043120221220101
Pubmed

Critical role of the p400/mDomino chromatin-remodeling ATPase in embryonic hematopoiesis.

SOX2 EP400

1.54e-043220217535249
Pubmed

A SOX17-PDGFB signaling axis regulates aortic root development.

SOX17 TNFAIP3

1.74e-043420235831318
Pubmed

Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors.

SOX17 SOX2

1.74e-043420230504829
Pubmed

Wnt5a and Wnt11 regulate mammalian anterior-posterior axis elongation.

SOX17 SOX2

1.85e-043520225813538
Pubmed

YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis.

SOX2 AMOTL2

2.42e-044020228323616
Pubmed

NOTCH activation interferes with cell fate specification in the gastrulating mouse embryo.

SOX17 SOX2

2.42e-044020226534985
Pubmed

Identification of molecular compartments and genetic circuitry in the developing mammalian kidney.

SOX17 EHF

2.42e-044020222510988
Pubmed

SOX4 regulates gonad morphogenesis and promotes male germ cell differentiation in mice.

SOX2 AMOTL2

2.54e-044120228118982
Pubmed

Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators.

SOX2 AMOTL2

2.67e-044220223863479
Pubmed

NANOG initiates epiblast fate through the coordination of pluripotency genes expression.

SOX17 SOX2

3.20e-044620235729116
Pubmed

Global expression analysis of gene regulatory pathways during endocrine pancreatic development.

SOX17 SOX2

4.58e-045520214660441
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

RC3H2 MYO19 CRTC2 TUBGCP4

4.62e-0465020438777146
InteractionKRT13 interactions

MEPCE SOX2 RC3H2 AMOTL2

4.70e-06116204int:KRT13
InteractionSMARCE1 interactions

SOX17 MEPCE SOX2 NRG1 AMOTL2

7.36e-06287205int:SMARCE1
InteractionPOU5F1 interactions

SOX17 SOX2 EP400 ZIC2 TUBGCP4 AMOTL2

1.58e-05584206int:POU5F1
InteractionHNF1B interactions

SOX17 SOX2 EP400 KMT2D

3.30e-05190204int:HNF1B
InteractionH2BC3 interactions

MEPCE EP400 RC3H2 STAG2 KMT2D

3.91e-05406205int:H2BC3
InteractionDBN1 interactions

MEPCE SOX2 DLGAP1 STAG2 MYO19

4.44e-05417205int:DBN1
InteractionWDR82 interactions

MEPCE SOX2 RC3H2 KMT2D

5.15e-05213204int:WDR82
InteractionHIGD1A interactions

RC3H2 STAG2 TUBGCP4

5.39e-0575203int:HIGD1A
InteractionCAPRIN1 interactions

MEPCE SOX2 DLGAP1 RC3H2 STAG2

6.45e-05451205int:CAPRIN1
InteractionNFIX interactions

SOX17 SOX2 EP400 KMT2D

6.59e-05227204int:NFIX
InteractionPOLDIP3 interactions

SOX17 MEPCE SOX2 RC3H2

7.79e-05237204int:POLDIP3
InteractionPRR12 interactions

SOX17 SOX2 STAG2

8.69e-0588203int:PRR12
InteractionTUBA1B interactions

MEPCE SOX2 RC3H2 STAG2 MYO19

1.03e-04498205int:TUBA1B
InteractionHOXA5 interactions

SOX17 MEPCE SOX2

1.06e-0494203int:HOXA5
InteractionDNTTIP1 interactions

TRERF1 SOX17 SOX2

1.09e-0495203int:DNTTIP1
InteractionACTG1 interactions

MEPCE EP400 RC3H2 MYO19 TUBGCP4

1.26e-04520205int:ACTG1
InteractionYWHAG interactions

MEPCE SOX2 DLGAP1 RC3H2 TNFAIP3 CRTC2 AMOTL2

1.30e-041248207int:YWHAG
InteractionYWHAE interactions

MEPCE SOX2 DLGAP1 RC3H2 TNFAIP3 CRTC2 AMOTL2

1.36e-041256207int:YWHAE
InteractionMIDEAS interactions

TRERF1 SOX17 SOX2

1.60e-04108203int:MIDEAS
InteractionMYL6B interactions

MEPCE SOX2 MYO19

1.60e-04108203int:MYL6B
InteractionARID3B interactions

SOX17 MEPCE SOX2

1.83e-04113203int:ARID3B
InteractionMRPS23 interactions

MEPCE SOX2 RC3H2 TUBGCP4

1.84e-04296204int:MRPS23
InteractionMRPS18B interactions

MEPCE SOX2 RC3H2 TUBGCP4

2.11e-04307204int:MRPS18B
InteractionGLIS3 interactions

CLNK SOX2

2.14e-0422202int:GLIS3
InteractionSEPSECS interactions

SOX2 TNFAIP3

2.34e-0423202int:SEPSECS
InteractionCPLANE1 interactions

SOX2 TUBGCP4

2.77e-0425202int:CPLANE1
InteractionRPL38 interactions

SOX17 MEPCE RC3H2 TUBGCP4

2.91e-04334204int:RPL38
InteractionSOX2 interactions

TRERF1 MEPCE SOX2 EP400 STAG2 KMT2D AMOTL2

2.93e-041422207int:SOX2
InteractionCCAR2 interactions

SOX17 MEPCE SOX2 RC3H2

3.01e-04337204int:CCAR2
InteractionKMT2C interactions

SOX17 SOX2 KMT2D

3.02e-04134203int:KMT2C
InteractionUPF3B interactions

MEPCE SOX2 RC3H2

3.15e-04136203int:UPF3B
InteractionCTNNB1 interactions

SOX17 SOX2 EP400 DLGAP1 KMT2D TNFAIP3

3.28e-041009206int:CTNNB1
InteractionNAP1L1 interactions

MEPCE SOX2 RC3H2 MYO19

3.29e-04345204int:NAP1L1
InteractionPHF10 interactions

SOX17 MEPCE SOX2

3.36e-04139203int:PHF10
InteractionLSM3 interactions

MEPCE SOX2 RC3H2

3.36e-04139203int:LSM3
InteractionYWHAB interactions

MEPCE DLGAP1 RC3H2 TNFAIP3 CRTC2 AMOTL2

3.37e-041014206int:YWHAB
InteractionFLNA interactions

MEPCE SOX2 RC3H2 STAG2 MYO19

3.51e-04648205int:FLNA
InteractionNFIB interactions

SOX17 SOX2 KMT2D

3.58e-04142203int:NFIB
InteractionNCOA6 interactions

SOX17 SOX2 KMT2D

3.80e-04145203int:NCOA6
InteractionITIH4 interactions

SOX2 DLGAP1

4.28e-0431202int:ITIH4
InteractionTLE3 interactions

TRERF1 SOX2 KMT2D CRTC2

4.56e-04376204int:TLE3
InteractionTRERF1 interactions

TRERF1 SOX2

4.85e-0433202int:TRERF1
InteractionHIP1R interactions

SOX2 STAG2 MYO19

4.98e-04159203int:HIP1R
InteractionKDM6A interactions

SOX17 SOX2 KMT2D

5.26e-04162203int:KDM6A
InteractionGAS2L3 interactions

SOX2 MYO19

5.46e-0435202int:GAS2L3
InteractionMSI2 interactions

MEPCE SOX2 RC3H2

5.84e-04168203int:MSI2
InteractionKMT2D interactions

SOX17 SOX2 KMT2D

5.95e-04169203int:KMT2D
InteractionTRAPPC14 interactions

RC3H2 AMOTL2

6.10e-0437202int:TRAPPC14
InteractionEGR2 interactions

TRERF1 EP400 KMT2D

6.15e-04171203int:EGR2
InteractionSPTBN2 interactions

SOX2 DLGAP1 MYO19

6.26e-04172203int:SPTBN2
InteractionSNRPD2 interactions

MEPCE SOX2 RC3H2 AMOTL2

6.55e-04414204int:SNRPD2
InteractionRBM15 interactions

SOX2 RC3H2 STAG2

6.58e-04175203int:RBM15
InteractionSP2 interactions

SOX2 RC3H2

6.78e-0439202int:SP2
InteractionKRT15 interactions

MEPCE TUBGCP4 AMOTL2

6.91e-04178203int:KRT15
InteractionSPTBN1 interactions

SOX2 DLGAP1 RC3H2 MYO19

6.98e-04421204int:SPTBN1
InteractionRPS15 interactions

MEPCE SOX2 RC3H2 TNFAIP3

7.10e-04423204int:RPS15
InteractionE2F7 interactions

MEPCE STAG2

7.14e-0440202int:E2F7
InteractionEXOSC2 interactions

MEPCE RC3H2 STAG2

7.14e-04180203int:EXOSC2
InteractionRPL27 interactions

MEPCE SOX2 RC3H2 TUBGCP4

7.62e-04431204int:RPL27
InteractionPSMD2 interactions

MEPCE SOX2 RC3H2 STAG2

7.88e-04435204int:PSMD2
InteractionRPL36A interactions

MEPCE RC3H2 TUBGCP4

8.10e-04188203int:RPL36A
InteractionNFIA interactions

SOX17 SOX2 KMT2D

8.10e-04188203int:NFIA
InteractionTHRAP3 interactions

MEPCE SOX2 RC3H2 STAG2

8.44e-04443204int:THRAP3
InteractionGTPBP4 interactions

SOX17 MEPCE SOX2 RC3H2

8.44e-04443204int:GTPBP4
InteractionNOP16 interactions

MEPCE SOX2 RC3H2

8.48e-04191203int:NOP16
InteractionRPL18A interactions

MEPCE SOX2 RC3H2 TUBGCP4

8.73e-04447204int:RPL18A
InteractionAKAP8 interactions

SOX2 RC3H2 STAG2

8.74e-04193203int:AKAP8
InteractionKLF5 interactions

SOX2 EP400 KMT2D

9.01e-04195203int:KLF5
InteractionLTV1 interactions

MEPCE SOX2 RC3H2

9.14e-04196203int:LTV1
InteractionZNF281 interactions

SOX17 SOX2 RC3H2

9.28e-04197203int:ZNF281
InteractionPWP1 interactions

SOX17 SOX2 RC3H2

9.41e-04198203int:PWP1
InteractionTRMT1L interactions

MEPCE SOX2 RC3H2

9.83e-04201203int:TRMT1L
InteractionPYGO2 interactions

SOX2 KMT2D

1.03e-0348202int:PYGO2
InteractionMRPL41 interactions

SOX2 RC3H2 TUBGCP4

1.04e-03205203int:MRPL41
InteractionRFC5 interactions

MEPCE SOX2 RC3H2

1.06e-03206203int:RFC5
InteractionPOLDIP2 interactions

MEPCE SOX2 RC3H2

1.10e-03209203int:POLDIP2
InteractionG3BP1 interactions

MEPCE SOX2 RC3H2 STAG2 TNFAIP3

1.11e-03835205int:G3BP1
InteractionNFIC interactions

SOX17 SOX2 KMT2D

1.12e-03210203int:NFIC
InteractionTUBA1C interactions

MEPCE RC3H2 STAG2 TUBGCP4

1.12e-03478204int:TUBA1C
InteractionNANOG interactions

TRERF1 SOX2 EP400 ZIC2

1.15e-03481204int:NANOG
InteractionGSN interactions

DLGAP1 RC3H2 MYO19

1.15e-03212203int:GSN
InteractionTRIP12 interactions

MEPCE SOX2 STAG2

1.18e-03214203int:TRIP12
InteractionMRPL23 interactions

MEPCE SOX2 RC3H2

1.26e-03219203int:MRPL23
InteractionMRPS14 interactions

MEPCE RC3H2 TUBGCP4

1.28e-03220203int:MRPS14
InteractionSPTAN1 interactions

SOX2 DLGAP1 RC3H2 MYO19

1.28e-03496204int:SPTAN1
InteractionHDAC2 interactions

MEPCE SOX2 EP400 STAG2 CRTC2

1.30e-03865205int:HDAC2
InteractionTUT1 interactions

MEPCE SOX2

1.35e-0355202int:TUT1
InteractionYWHAZ interactions

MEPCE SOX2 NRG1 DLGAP1 TNFAIP3 CRTC2

1.36e-031319206int:YWHAZ
InteractionIGF2BP1 interactions

MEPCE SOX2 RC3H2 TUBGCP4

1.40e-03508204int:IGF2BP1
InteractionKLF3 interactions

SOX2 EP400 KMT2D

1.41e-03228203int:KLF3
InteractionFOXC1 interactions

SOX17 SOX2 RC3H2

1.41e-03228203int:FOXC1
InteractionSEPTIN7 interactions

SOX2 DLGAP1 KMT2D

1.41e-03228203int:SEPTIN7
InteractionDYNLL1 interactions

CLNK DLGAP1 RC3H2 AMOTL2

1.42e-03510204int:DYNLL1
InteractionRPS20 interactions

MEPCE SOX2 RC3H2 TNFAIP3

1.45e-03513204int:RPS20
InteractionXRCC5 interactions

MEPCE SOX2 RC3H2 EHF

1.47e-03515204int:XRCC5
InteractionCCT4 interactions

MEPCE SOX2 RC3H2 MYO19

1.47e-03515204int:CCT4
GeneFamilySRY-boxes

SOX17 SOX2

8.10e-0519132757
GeneFamilyAtaxins|Trinucleotide repeat containing

EP400 KMT2D

1.42e-0425132775
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

TRERF1 EP400

6.44e-0453132532
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_11|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CLNK HYAL3 EHF

5.09e-05163203a09449a502627aa369db600dba5bda93de7ce5c0
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

CLNK TRERF1 EHF

5.66e-05169203a4204bdd75837f5fee9aaac459cb4c19ee2a7bf4
ToppCellwk_20-22-Epithelial-Proximal_epithelial-basal_late|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SOX2 NRG1 EHF

6.61e-0517820303f22485074b3cbf9a6ad4d543c5bbfa826dc741
ToppCellEpithelial-basal_cell|World / Lineage, Cell type, age group and donor

SOX2 NRG1 EHF

6.72e-05179203d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_late|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SOX2 NRG1 EHF

6.83e-05180203255097d8eb244a32eb2ecd0e7e48e1a20bafb5cd
ToppCell10x5'v1-week_14-16-Lymphocytic_NK-T_NK-ILC_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CLNK TNFAIP3 EHF

6.83e-05180203a999a6d219a8e58a8b63802ddf8c95ffaab9cfa0
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX2 DLGAP1 HYAL3

7.17e-051832038330c39184ce076e1f95fd3725b68af551d89db0
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_proximal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SOX2 NRG1 EHF

7.29e-05184203575de705053da8b289670b5c40c1627c0833b5ed
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SOX2 NRG1 ZIC2

7.53e-05186203c7983281a290201567b398e9ea6baddb96c692bb
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SOX2 NRG1 EHF

7.77e-051882033cfba3addcc9058f4ec31ad96261f79988f551a0
ToppCellfacs-Lung-EPCAM-18m-Epithelial-Basal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX2 NRG1 EHF

7.89e-05189203783c1db856f2defe6f3b8748dd0bc29a8102f6d1
ToppCelldroplet-Tongue-nan-24m-Epithelial-basal_cell_of_epidermis|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRG1 TNFAIP3 EHF

7.89e-05189203258ef4a52f90236dbed92f325ca033c8fa6156a5
ToppCellfacs-Lung-EPCAM-18m-Epithelial-respiratory_basal_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX2 NRG1 EHF

7.89e-0518920388b72fafbe58463543e0818f27f3dd9e5b4d34d2
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX2 NRG1 EHF

8.02e-0519020347e07ea22733306d8885ee9e5f0b033e2f5e2afb
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX2 NRG1 EHF

8.02e-05190203261b8afddfdcba4f70b50df126cef7ad00a0aae0
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SOX2 NRG1 EHF

8.14e-0519120360ff989fe99d243a3d52955223680cdd1f1917a4
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 NRG1 AMOTL2

8.27e-0519220324d28e28a5c54ca7770f7e5ad7f4d00039e0aaf9
ToppCellfacs-Lung-EPCAM-18m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX2 NRG1 EHF

8.27e-0519220312096302a3a4d26e21ca04357aa557143f482155
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX2 NRG1 EHF

8.40e-05193203739fb2a57772a800a2e94bdd6c71285bb2c162a7
ToppCellwk_08-11-Epithelial-Proximal_epithelial-basal_intermediate_|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SOX2 NRG1 EHF

8.40e-0519320383d2dd823808a2b5ca1a6889eefb541ec042b24c
ToppCell18-Airway-Epithelial-Basal_cell|Airway / Age, Tissue, Lineage and Cell class

SOX2 NRG1 EHF

8.40e-051932035067b0db24f96e26cf3f9437736415f694e7a614
ToppCellPCW_13-14-Epithelial-Epithelial_airway|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SOX2 NRG1 EHF

8.53e-051942037b2b40a56eb9c7203ca50133b2da4fd8fdd4a5cf
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SOX2 NRG1 EHF

8.53e-051942036b286992d4bb56013c0ea5a7601d3476d806175a
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SOX2 NRG1 EHF

8.53e-05194203f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SOX2 NRG1 EHF

8.66e-05195203d673f8844896d5c7b76a7bc7f6b88a039f1bc263
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX2 NRG1 EHF

8.66e-05195203ed052c6d3dc104b02e34b645abfdee477af050c6
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_basal-Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SOX2 EHF AMOTL2

8.79e-05196203c5adab88140a465698abcbedc6505a43cae7bfd1
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids|BALF-PFMC / Compartment, severity and other cell annotations on 10x 3' data (130k)

SOX2 EHF AMOTL2

8.92e-05197203495bfdb40b640591fbbaaa99f419bb6468cef405
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SOX2 EHF AMOTL2

8.92e-05197203ac9c0c25cfeaabd53d332982c73fc6c47b0c6478
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SOX2 EHF AMOTL2

8.92e-05197203b57d2e3413ef6dd1da56c45087926f2f3eab876c
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_TRM/EMRA|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CLNK TRERF1 TNFAIP3

9.06e-0519820390863377ed36afc30bc1a068612ad1adc77af5a8
ToppCellPCW_10-12-Epithelial-Epithelial_airway|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SOX2 NRG1 EHF

9.06e-051982039a12e5e47236433e512c668005fe3f8be6fde95c
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CLNK DLGAP1 TNFAIP3

9.06e-05198203d021d0edb6aba2f15c51a3ec4e08c7233d0c1962
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SOX2 NRG1 EHF

9.33e-05200203afac850d5a40de0d6f02857cf81a19443d90b1eb
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_basal-Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SOX2 NRG1 EHF

9.33e-052002039da214f756a03516eaafde00289b90f69623b9f3
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-gdT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CLNK TRERF1 TNFAIP3

9.33e-052002031779a8ff4443a85ac500f849764e86d9c7529b84
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SOX2 NRG1 EHF

9.33e-052002032a9d715aba8bdef2341b0d44ff60825c074a4b03
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal-Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SOX2 NRG1 EHF

9.33e-052002030594ca7bc313b73e1dc800cf058f8f798b0284cb
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-erythrocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLNK TUBGCP4

4.97e-04742026f222ebf7cb106bbb2ae3fb3cda660dfec3ea5d0
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Gpr50|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CLNK EHF

9.23e-041012026523c314166dcf66c3ed13c02ca4b886b068e5b8
ToppCelldroplet-Heart-nan-24m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 AMOTL2

1.19e-03115202e11128262ba1e2a7053b1b6c039f1aab37d2ce27
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLNK EHF

1.21e-03116202a07f16917c66ce25f23ebef350d693cc4c324075
ToppCellBAL-Control-cDC_7|Control / Compartment, Disease Groups and Clusters

NRG1 KMT2D

1.32e-03121202b49b044a687a31883dfccecf10a183b5ba567f7a
ToppCell(5)_Dendritic_cell-(51)_cDC1|(5)_Dendritic_cell / shred on Cell_type and subtype

CLNK TRERF1

1.36e-03123202d46cfdf8b3e561d8db33903207d5151cdb2a91d4
ToppCellLymphoid-T_cells_(Cd8+_T_cell)|World / shred on cell class and cell subclass (v4)

CLNK TNFAIP3

1.74e-03139202c85f50fb536f4df6fa4dbdebe48e1ecea1df1121
ToppCellAT1-AT2_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

NRG1 AMOTL2

1.76e-0314020245d52a086ced8d58e01ac51ac4a90338e8649b16
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLNK MYO19

1.76e-03140202e64f6aa57bc069cfe970089bd1c298433bfaf771
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_4|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

TRERF1 TNFAIP3

1.84e-03143202091708a47ac55c6585923ee30190ff296fa87f6f
ToppCellmild_COVID-19_(asymptomatic)-Treg|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

CLNK DLGAP1

1.89e-031452022d0903009e918500facfd017ff31f2cec1e76131
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

SOX17 TNFAIP3

1.89e-0314520237580218f6a6f65a1d827cbcf59465f8827f9a55
ToppCellmild_COVID-19_(asymptomatic)-Treg|World / disease group, cell group and cell class (v2)

CLNK DLGAP1

1.89e-03145202a3b0e1d0ce0caa8b281a146439d6455db64cc3e5
ToppCellAdult-Immune-dendritic_cell-D231|Adult / Lineage, Cell type, age group and donor

CLNK TRERF1

1.94e-031472027cc4f74dd7a86247db8dc049ed7eadeb53825a96
ToppCellE18.5-samps-Epithelial-Epithelial-non_alveolar-Club_cell|E18.5-samps / Age Group, Lineage, Cell class and subclass

SOX2 EHF

1.99e-0314920282edfecb7981d8c336cf9da7aa7e2b3f7a017a3f
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_dendritic-myeloid_dendritic_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CLNK HYAL3

1.99e-0314920271d72a6e7b128ee96161e08f6a0d77be925e73a1
ToppCellE18.5-samps-Epithelial-Epithelial-non_alveolar|E18.5-samps / Age Group, Lineage, Cell class and subclass

SOX2 EHF

1.99e-0314920214a01ae540db8a350ea26a350b2e6ce6c07639d9
ToppCelldroplet-Heart-4Chambers-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRTC2 EHF

1.99e-0314920238890ddde0979977c8350f01497f1245ab51641a
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CLNK AMOTL2

2.02e-03150202ecc4fc94958cf2378dd003966dccba81b3c00f8e
ToppCellfacs-GAT-Fat-3m-Lymphocytic-NK_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLNK TNFAIP3

2.04e-031512023d07b79ecbcfad13116f0f2b039bd181a7ffe853
ToppCellTransverse-Dendritic_cell-cDC1|Dendritic_cell / Region, Cell class and subclass

CLNK TRERF1

2.04e-031512026870f3b5d2bfad849c3203658b5f28f0ae181295
ToppCelldroplet-Fat-Scat-21m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLNK TNFAIP3

2.04e-0315120279827a76c675dcb82f59c0a45d0f962b02d5bfd6
ToppCellCOVID-19_Severe-multiplets|COVID-19_Severe / disease group, cell group and cell class

CLNK EHF

2.07e-03152202451745151322c2fcea22dbb3dba681e12634a510
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYO19 TUBGCP4

2.10e-0315320288ca2d2c2ab19fbee13e18951b993ee05dd30f67
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYO19 TUBGCP4

2.10e-03153202553dff9688a1996d8f4ba16e60c683593d781389
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CLNK EHF

2.12e-03154202ce4b1e878cd88065fbfd2df18caf19703fec37d8
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NRG1 HYAL3

2.12e-03154202e65e4636646164610f33f7bbac0d879a3ea55986
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CLNK AMOTL2

2.12e-031542028dc8f02534c3ebda30bf9e702e36d0c53d89e5a5
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CLNK EHF

2.12e-031542025967a0a33456d5930fc492a700ebb015ac050abb
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CLNK SOX2

2.15e-03155202105d59d8a1bb8cb37eef2c1767d737b2108ac7c5
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|343B / Donor, Lineage, Cell class and subclass (all cells)

TNFAIP3 CRTC2

2.15e-03155202a4ff78e2efc6fe9a513bb2b64e5848f2ce65a09f
ToppCellMonocytes-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

NRG1 TNFAIP3

2.15e-0315520282abfcee23ba08a1eb4208d367393285026e5388
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CLNK EHF

2.15e-03155202fab281db4c275d51240b122be78713c839ba5a95
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLNK TNFAIP3

2.18e-0315620239aa3adbee9f04cdc0055487d393edfa515e062b
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLNK TNFAIP3

2.18e-03156202a09e3aefe78d63ad5428ad48c6f83e547eb819f6
ToppCellsevere_COVID-19-cDC|severe_COVID-19 / disease group, cell group and cell class (v2)

CLNK EHF

2.21e-03157202ec1978e07e2214048d015d8bb793c1d9991f6e37
ToppCellfacs-MAT-Fat-18m-Lymphocytic-NK_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLNK TNFAIP3

2.21e-03157202e6846ffd1bb18bf0469bc6d49ab6cf3533d9cde6
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-cDC1|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLNK EHF

2.23e-0315820278a8a498a9c84ed65e0eefaac781d5247c5b477a
ToppCellFetal_29-31_weeks-Immune-mast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CLNK TNFAIP3

2.23e-031582020c27c475289c70b17b6a66fc71f628511c5f0ae1
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SOX2 EHF

2.23e-0315820298712ed7e8e65e8c5ff9318cf0e0a04e271a055d
ToppCellControl-Myeloid-Monocytes,_Macrophages-Mast-cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLNK HYAL3

2.26e-0315920281782e9e370558d61af5e0c760ac9759d69fb725
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MEPCE NRG1

2.26e-03159202ded4e3626a62fb6334403b7213b467fb7e8131c3
ToppCellClub_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

SOX2 EHF

2.26e-03159202a7bcff268b1962a561fd2848e01ae16565bce895
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Lymphocytic-mature_NK_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLNK TNFAIP3

2.26e-0315920232d4c9f7ba6a96ce8443396b80568b41cbfc4927
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MEPCE NRG1

2.26e-031592022f6c60ddff2208a68146f9786143d9aefd528840
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX2 EHF

2.29e-03160202028b5261a1da832d52f66fb620db83e5fbbd874a
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX2 EHF

2.29e-03160202b4844a8c7755a2b2868019791d8d224154973445
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLNK TNFAIP3

2.29e-031602026b0faaa371650563f585722f5b2fb319e124ec38
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX2 EHF

2.29e-031602021f4ee446436726c3d373f56d87dd80b6a12e8b9e
ToppCell10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-LMPP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SOX17 EP400

2.29e-0316020260fa1c717410aad7e8647703cb416cd7617cac29
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX2 EHF

2.29e-0316020201ae730e9d0d05f3277f862f0c09bafb32b89db5
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX2 EHF

2.29e-031602026de9e7be1d860d82d503bfbc779e72f072a6efc3
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CLNK DLGAP1

2.32e-03161202b24293fdae9637983fcf4f2d4659a3554e00a53f
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLNK TRERF1

2.32e-03161202afc719ffa53ab34c5628da47936da1f731dceab1
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX2 EHF

2.32e-031612022d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX2 EHF

2.32e-0316120241a89a3d99a9bd6039a3d881d1d9dcd18bc07f25
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX2 EHF

2.32e-03161202c4970501c038ed36de447da70eabff020ad78713
ToppCell10x5'-bone_marrow-Myeloid_Dendritic-DC1|bone_marrow / Manually curated celltypes from each tissue

CLNK EHF

2.32e-031612022f068ee643de2f647c289779a6624265ab9a749b
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLNK TNFAIP3

2.32e-031612026d9907e2949a742c0933128fde57832a9ca5f77c
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLNK TNFAIP3

2.35e-031622025731f9514434296132df4bc86f78ce87b07cdeca
ToppCellAT1_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

NRG1 AMOTL2

2.35e-03162202ae2ba4f21f6f6c512006fa531d670b88be7c04c9
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLNK TNFAIP3

2.35e-031622020321fc954ae4ad67ca438cbbc84632562d222188
Diseaseholoprosencephaly (is_implicated_in)

STAG2 ZIC2

1.22e-058202DOID:4621 (is_implicated_in)
Diseaseintracranial aneurysm (is_implicated_in)

SOX17 KMT2D

2.87e-0512202DOID:10941 (is_implicated_in)
DiseaseLymphoma, Large-Cell, Follicular

KMT2D TNFAIP3

4.56e-0515202C0079745
DiseaseLymphoma, Small Cleaved-Cell, Follicular

KMT2D TNFAIP3

4.56e-0515202C0079765
DiseaseLymphoma, Mixed-Cell, Follicular

KMT2D TNFAIP3

4.56e-0515202C0079758
DiseaseLymphoma, Follicular, Grade 2

KMT2D TNFAIP3

4.56e-0515202C1956132
DiseaseLymphoma, Follicular, Grade 3

KMT2D TNFAIP3

4.56e-0515202C1956131
DiseaseLymphoma, Follicular, Grade 1

KMT2D TNFAIP3

4.56e-0515202C1956130
DiseaseLymphoma, Follicular

KMT2D TNFAIP3

8.23e-0520202C0024301
DiseaseBladder Neoplasm

SOX2 STAG2 KMT2D

1.12e-04140203C0005695
DiseaseMalignant neoplasm of urinary bladder

SOX2 STAG2 KMT2D

1.15e-04141203C0005684
Diseaseejection fraction measurement

DLGAP1 TNFAIP3

3.88e-0443202EFO_0005527
DiseaseProstatic Neoplasms

SOX2 KMT2D EHF ZIC2

6.98e-04616204C0033578
DiseaseMalignant neoplasm of prostate

SOX2 KMT2D EHF ZIC2

6.98e-04616204C0376358
Diseaserheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement

CLNK TNFAIP3

8.32e-0463202EFO_0000685, EFO_0007791, EFO_0009459
Diseasecholangiocarcinoma (is_marker_for)

SOX2 TNFAIP3

8.58e-0464202DOID:4947 (is_marker_for)
Diseasesclerosing cholangitis

CLNK TNFAIP3

9.12e-0466202EFO_0004268
Diseaseschizophrenia (implicated_via_orthology)

NRG1 ZIC2

9.68e-0468202DOID:5419 (implicated_via_orthology)
Diseaseesophagus squamous cell carcinoma (is_marker_for)

KMT2D TNFAIP3

1.14e-0374202DOID:3748 (is_marker_for)
DiseaseSquamous cell carcinoma of esophagus

SOX2 KMT2D

1.88e-0395202C0279626
Diseasespontaneous preterm birth

DLGAP1 SPATA6

2.12e-03101202EFO_0006917
Diseasemalaria

NRG1 TNFAIP3

2.16e-03102202EFO_0001068
Diseasetreatment-resistant hypertension

CLNK DLGAP1

2.46e-03109202EFO_1002006
Diseaserheumatoid arthritis

CLNK DLGAP1 TNFAIP3

3.57e-03462203EFO_0000685
DiseaseNeoplastic Cell Transformation

NRG1 TNFAIP3

3.96e-03139202C0007621

Protein segments in the cluster

PeptideGeneStartEntry
RQEPQGQEHQGGENH

AMOTL2

71

Q9Y2J4
MHHGTGPQNVQHQLQ

EP400

1

Q96L91
ANAQIHGPASQHMGN

DLGAP1

606

O14490
GMAVENGHPVQQHQK

RC3H2

1096

Q9HBD1
RNNMMNIANGPHHPN

NRG1

286

Q02297
QAQQHRGGGPQAQSH

MEPCE

81

Q7L2J0
MLQQVNGHNPGSDGQ

MYO19

1

Q96H55
VQQQDHHPSQQGQGG

TUBGCP4

66

Q9UGJ1
MGGPQDPHTFNHQNL

CRTC2

591

Q53ET0
GGVMNLNPGNNLLHQ

EHF

6

Q9NZC4
GIIANRGQHFHGQNM

HYAL3

56

O43820
PQHPGLNAHGAAQMQ

SOX2

181

P48431
GGGRGFQMQPQHQHQ

SOX17

306

Q9H6I2
NHSVQNRDHRGGMQP

CLNK

251

Q7Z7G1
CQHPNQRMGPGAHRG

TNFAIP3

736

P21580
GPNRMNGHHQQNGVE

STAG2

66

Q8N3U4
GQASQREGHLQQGNM

nan

291

A8MX80
PGPNQMSGHHDSNRQ

SPATA6

111

Q9NWH7
HGPHGSQNVLNGQMR

ZIC2

166

O95409
PSGIHLNNMGPQHQQ

TRERF1

456

Q96PN7
SNQGHMLSGQHGGQA

KMT2D

3351

O14686