Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionfour-way junction DNA binding

HMGB1 HMGB3

1.61e-0419202GO:0000400
GeneOntologyMolecularFunctionDNA binding, bending

HMGB1 HMGB3

1.79e-0420202GO:0008301
GeneOntologyMolecularFunctionhistone H3 demethylase activity

KDM2B KDM5D

3.55e-0428202GO:0141052
GeneOntologyMolecularFunctionhistone demethylase activity

KDM2B KDM5D

4.36e-0431202GO:0032452
GeneOntologyMolecularFunctionprotein demethylase activity

KDM2B KDM5D

4.64e-0432202GO:0140457
GeneOntologyMolecularFunctionDNA secondary structure binding

HMGB1 HMGB3

7.63e-0441202GO:0000217
GeneOntologyMolecularFunctiondemethylase activity

KDM2B KDM5D

8.79e-0444202GO:0032451
GeneOntologyMolecularFunctionhistone modifying activity

KDM2B KMT2C KDM5D

1.47e-03229203GO:0140993
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

KDM2B KDM5D

1.91e-0365202GO:0016706
GeneOntologyMolecularFunctiondouble-stranded RNA binding

HMGB1 STAU1

2.73e-0378202GO:0003725
GeneOntologyMolecularFunctionrRNA binding

KDM2B HMGB1

2.80e-0379202GO:0019843
GeneOntologyMolecularFunctiondioxygenase activity

KDM2B KDM5D

4.28e-0398202GO:0051213
GeneOntologyBiologicalProcesspositive regulation of hematopoietic progenitor cell differentiation

HMGB1 FLT1

3.20e-059202GO:1901534
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

SLC12A6 KDM2B RNF213 HMGB1 FLT1 PRX DLX5 CNTN1

4.03e-051483208GO:0048646
GeneOntologyBiologicalProcesssensory organ development

KDM2B HMGB1 KMT2C FLT1 DLX5 ZEB1

4.88e-05730206GO:0007423
GeneOntologyBiologicalProcesseye development

KDM2B HMGB1 KMT2C FLT1 ZEB1

7.76e-05480205GO:0001654
GeneOntologyBiologicalProcessvisual system development

KDM2B HMGB1 KMT2C FLT1 ZEB1

7.99e-05483205GO:0150063
GeneOntologyBiologicalProcesssensory system development

KDM2B HMGB1 KMT2C FLT1 ZEB1

8.64e-05491205GO:0048880
GeneOntologyBiologicalProcessregulation of lymphocyte differentiation

HMGB1 HMGB3 ZAP70 ZEB1

1.11e-04266204GO:0045619
GeneOntologyBiologicalProcesssensory organ morphogenesis

KDM2B FLT1 DLX5 ZEB1

2.95e-04343204GO:0090596
GeneOntologyBiologicalProcessmyelin assembly

PRX CNTN1

3.33e-0428202GO:0032288
GeneOntologyBiologicalProcessembryonic camera-type eye morphogenesis

KDM2B ZEB1

4.35e-0432202GO:0048596
GeneOntologyBiologicalProcesstube morphogenesis

SLC12A6 KDM2B RNF213 HMGB1 FLT1 ZEB1

5.20e-041125206GO:0035239
GeneOntologyBiologicalProcesscamera-type eye morphogenesis

KDM2B FLT1 ZEB1

5.75e-04171203GO:0048593
GeneOntologyBiologicalProcesspotassium ion homeostasis

SLC12A6 ATP4A

5.83e-0437202GO:0055075
GeneOntologyBiologicalProcessembryonic eye morphogenesis

KDM2B ZEB1

6.15e-0438202GO:0048048
GeneOntologyBiologicalProcesscamera-type eye development

KDM2B KMT2C FLT1 ZEB1

6.69e-04426204GO:0043010
GeneOntologyBiologicalProcessregulation of leukocyte differentiation

HMGB1 HMGB3 ZAP70 ZEB1

6.86e-04429204GO:1902105
GeneOntologyBiologicalProcessregulation of mesenchymal cell proliferation

HMGB1 ZEB1

8.62e-0445202GO:0010464
GeneOntologyBiologicalProcessembryonic camera-type eye development

KDM2B ZEB1

8.62e-0445202GO:0031076
GeneOntologyBiologicalProcessregulation of hematopoietic progenitor cell differentiation

HMGB1 FLT1

9.01e-0446202GO:1901532
GeneOntologyBiologicalProcesseye morphogenesis

KDM2B FLT1 ZEB1

9.60e-04204203GO:0048592
GeneOntologyBiologicalProcessregulation of RNA splicing

AHNAK PRX AHNAK2

1.00e-03207203GO:0043484
GeneOntologyBiologicalProcesspotassium ion import across plasma membrane

SLC12A6 ATP4A

1.11e-0351202GO:1990573
GeneOntologyBiologicalProcesssprouting angiogenesis

RNF213 HMGB1 FLT1

1.19e-03220203GO:0002040
GeneOntologyBiologicalProcessregulation of T cell differentiation

HMGB1 ZAP70 ZEB1

1.29e-03226203GO:0045580
GeneOntologyBiologicalProcessmonocyte chemotaxis

HMGB1 FLT1

1.33e-0356202GO:0002548
GeneOntologyBiologicalProcessregulation of epithelial cell proliferation

HMGB1 FLT1 DLX5 ZEB1

1.34e-03514204GO:0050678
GeneOntologyBiologicalProcessmesenchymal cell proliferation

HMGB1 ZEB1

1.48e-0359202GO:0010463
GeneOntologyBiologicalProcessregulation of vascular endothelial cell proliferation

HMGB1 FLT1

1.48e-0359202GO:1905562
GeneOntologyBiologicalProcessvascular endothelial cell proliferation

HMGB1 FLT1

1.53e-0360202GO:0101023
GeneOntologyBiologicalProcesslymphocyte differentiation

HMGB1 HMGB3 ZAP70 ZEB1

1.58e-03537204GO:0030098
GeneOntologyBiologicalProcessregulation of hemopoiesis

HMGB1 HMGB3 ZAP70 ZEB1

1.61e-03540204GO:1903706
GeneOntologyBiologicalProcesstube development

SLC12A6 KDM2B RNF213 HMGB1 FLT1 ZEB1

1.65e-031402206GO:0035295
GeneOntologyBiologicalProcessmononuclear cell migration

HMGB1 ZAP70 FLT1

1.88e-03258203GO:0071674
GeneOntologyBiologicalProcesspositive regulation of viral process

HMGB1 STAU1

2.02e-0369202GO:0048524
GeneOntologyBiologicalProcessnegative regulation of lymphocyte differentiation

HMGB1 HMGB3

2.07e-0370202GO:0045620
GeneOntologyCellularComponentcostamere

AHNAK AHNAK2

1.99e-0422202GO:0043034
MousePhenoturbinate hypoplasia

DLX5 ZEB1

9.38e-064182MP:0004477
MousePhenodecreased lateral semicircular canal size

DLX5 ZEB1

3.28e-057182MP:0003162
MousePhenojoint dislocation

ZAP70 ZEB1

7.00e-0510182MP:0030795
MousePhenoabnormal turbinate morphology

DLX5 ZEB1

8.55e-0511182MP:0002244
MousePhenoabnormal olfactory bulb mitral cell layer morphology

DLX5 ZEB1

8.55e-0511182MP:0009951
MousePhenoabnormal crista ampullaris neuroepithelium morphology

DLX5 ZEB1

8.55e-0511182MP:0004409
MousePhenoabnormal pterygoid bone morphology

DLX5 ZEB1

1.03e-0412182MP:0004453
MousePhenoabnormal olfactory bulb glomerular layer morphology

DLX5 ZEB1

1.03e-0412182MP:0009948
MousePhenoshort premaxilla

DLX5 ZEB1

1.21e-0413182MP:0000091
MousePhenoabnormal olfactory neuron innervation pattern

DLX5 ZEB1

1.21e-0413182MP:0012014
MousePhenoabnormal mandibular angle morphology

DLX5 ZEB1

1.63e-0415182MP:0004596
MousePhenoabnormal superior semicircular canal morphology

DLX5 ZEB1

1.86e-0416182MP:0003069
MousePhenodecreased cochlea coiling

DLX5 ZEB1

2.11e-0417182MP:0003148
MousePhenoabnormal mandibular condyloid process morphology

DLX5 ZEB1

2.11e-0417182MP:0004595
MousePhenoabnormal mandibular coronoid process morphology

DLX5 ZEB1

2.37e-0418182MP:0004594
MousePhenoabnormal olfactory nerve morphology

DLX5 ZEB1

2.37e-0418182MP:0005236
MousePhenoabnormal posterior semicircular canal morphology

DLX5 ZEB1

2.93e-0420182MP:0002858
MousePhenometeorism

DLX5 ZEB1

2.93e-0420182MP:0009247
MousePhenoabnormal pterygoid process morphology

DLX5 ZEB1

3.24e-0421182MP:0004452
MousePhenoabnormal lateral semicircular canal morphology

DLX5 ZEB1

3.24e-0421182MP:0000037
MousePhenoabnormal olfactory bulb layer morphology

DLX5 ZEB1

3.56e-0422182MP:0009946
MousePhenoabnormal physiological neovascularization

RNF213 FLT1

3.56e-0422182MP:0003710
MousePhenoabnormal mandibular ramus morphology

DLX5 ZEB1

3.90e-0423182MP:0010150
MousePhenosmall premaxilla

DLX5 ZEB1

4.62e-0425182MP:0004870
MousePhenoabnormal crista ampullaris morphology

DLX5 ZEB1

5.80e-0428182MP:0004249
MousePhenoabnormal limb posture

SLC12A6 CNTN1

5.80e-0428182MP:0004263
MousePhenoabnormal maxillary shelf morphology

DLX5 ZEB1

6.23e-0429182MP:0004538
MousePhenoabnormal endolymphatic duct morphology

DLX5 ZEB1

7.12e-0431182MP:0006011
MousePhenoabnormal semicircular canal ampulla morphology

DLX5 ZEB1

7.59e-0432182MP:0008488
MousePhenoabnormal T cell compartment

ZAP70 ZEB1

9.09e-0435182MP:0013887
MousePhenoabnormal T cell subpopulation ratio

ZAP70 ZEB1

9.09e-0435182MP:0003944
MousePhenoabnormal metatarsal bone morphology

DLX5 ZEB1

9.61e-0436182MP:0003072
MousePhenoshort maxilla

DLX5 ZEB1

1.13e-0339182MP:0000097
MousePhenoabnormal premaxilla morphology

DLX5 ZEB1

1.13e-0339182MP:0002820
MousePhenoimpaired humoral immune response

ZAP70 ZEB1

1.19e-0340182MP:0020154
MousePhenoabnormal Meckel's cartilage morphology

DLX5 ZEB1

1.25e-0341182MP:0005587
MousePhenoabnormal nasal septum morphology

DLX5 ZEB1

1.64e-0347182MP:0002239
MousePhenoabnormal olfactory epithelium morphology

DLX5 ZEB1

1.71e-0348182MP:0008789
MousePhenoabnormal ligament morphology

SLC12A6 DLX5

1.78e-0349182MP:0005504
MousePhenoabnormal cranial cartilage morphology

DLX5 ZEB1

1.85e-0350182MP:0030464
MousePhenoabnormal palate bone morphology

DLX5 ZEB1

1.92e-0351182MP:0009891
MousePhenoabnormal axon morphology

SLC12A6 PRX CNTN1

1.98e-03199183MP:0005404
MousePhenoabnormal neurite morphology

SLC12A6 PRX CNTN1 STAU1

2.12e-03442184MP:0008415
MousePhenoabnormal macrophage chemotaxis

PON2 FLT1

2.31e-0356182MP:0010760
MousePhenoabnormal olfactory system morphology

DLX5 ZEB1

2.31e-0356182MP:0005499
MousePhenodecreased interleukin-2 secretion

ZAP70 AHNAK

2.40e-0357182MP:0008688
MousePhenoabnormal basisphenoid bone morphology

DLX5 ZEB1

2.40e-0357182MP:0000106
MousePhenocurly tail

KDM2B ZEB1

2.40e-0357182MP:0003051
MousePhenoabnormal nerve conduction

SLC12A6 PRX

2.57e-0359182MP:0005403
MousePhenosmall maxilla

DLX5 ZEB1

2.57e-0359182MP:0004540
MousePhenoimpaired limb coordination

SLC12A6 CNTN1

2.57e-0359182MP:0001524
MousePhenoabnormal semicircular canal morphology

DLX5 ZEB1

2.57e-0359182MP:0002428
MousePhenoabnormal head development

KDM2B DLX5

2.83e-0362182MP:0012176
MousePhenoopen neural tube

KDM2B DLX5 ZEB1

2.84e-03226183MP:0000929
MousePhenoabnormal inner ear canal morphology

DLX5 ZEB1

2.92e-0363182MP:0002729
MousePhenosmall lymph nodes

ZAP70 ZEB1

2.92e-0363182MP:0002217
MousePhenoexencephaly

KDM2B DLX5 ZEB1

2.99e-03230183MP:0000914
MousePhenoshort mandible

DLX5 ZEB1

3.01e-0364182MP:0000088
MousePhenodistended abdomen

DLX5 ZEB1

3.10e-0365182MP:0001270
MousePhenoabnormal intervertebral disk morphology

DLX5 ZEB1

3.30e-0367182MP:0004173
MousePhenoabnormal hard palate morphology

DLX5 ZEB1

3.30e-0367182MP:0003756
MousePhenoabnormal symphysis morphology

DLX5 ZEB1

3.69e-0371182MP:0030877
MousePhenoabnormal cochlea morphology

SLC12A6 DLX5 ZEB1

3.70e-03248183MP:0000031
MousePhenoabnormal nervous system development

KDM2B PRX DLX5 ZEB1 CNTN1 STAU1

3.76e-031257186MP:0003861
DomainHMG_boxA_CS

HMGB1 HMGB3

3.27e-063202IPR017967
DomainHMG_box

HMGB1 KMT2C HMGB3

2.38e-0553203PF00505
DomainHMG

HMGB1 KMT2C HMGB3

2.52e-0554203SM00398
DomainHMG_box_2

HMGB1 HMGB3

3.90e-059202PF09011
DomainHMG_box_dom

HMGB1 KMT2C HMGB3

4.40e-0565203IPR009071
DomainHMG_BOX_1

HMGB1 HMGB3

4.88e-0510202PS00353
DomainZnf_PHD-finger

KDM2B KMT2C KDM5D

7.88e-0579203IPR019787
DomainPHD

KDM2B KMT2C KDM5D

1.12e-0489203SM00249
DomainZnf_PHD

KDM2B KMT2C KDM5D

1.20e-0491203IPR001965
DomainZF_PHD_2

KDM2B KMT2C KDM5D

1.36e-0495203PS50016
DomainZF_PHD_1

KDM2B KMT2C KDM5D

1.41e-0496203PS01359
DomainJmjC

KDM2B KDM5D

2.96e-0424202PF02373
DomainPDZ

AHNAK PRX AHNAK2

4.37e-04141203PF00595
DomainZnf_FYVE_PHD

KDM2B KMT2C KDM5D

4.94e-04147203IPR011011
DomainPDZ

AHNAK PRX AHNAK2

5.03e-04148203SM00228
Domain-

AHNAK PRX AHNAK2

5.24e-041502032.30.42.10
DomainJMJC

KDM2B KDM5D

5.30e-0432202PS51184
DomainJmjC_dom

KDM2B KDM5D

5.30e-0432202IPR003347
DomainPDZ

AHNAK PRX AHNAK2

5.34e-04151203PS50106
DomainPDZ

AHNAK PRX AHNAK2

5.44e-04152203IPR001478
DomainJmjC

KDM2B KDM5D

5.64e-0433202SM00558
Domain-

KDM2B RNF213 KMT2C KDM5D

1.18e-034492043.30.40.10
DomainZnf_RING/FYVE/PHD

KDM2B RNF213 KMT2C KDM5D

1.28e-03459204IPR013083
DomainHMG_BOX_2

HMGB1 HMGB3

1.51e-0354202PS50118
Domain-

HMGB1 HMGB3

1.56e-03552021.10.30.10
DomainPHD

KMT2C KDM5D

2.88e-0375202PF00628
DomainTyrKc

ZAP70 FLT1

3.95e-0388202SM00219
DomainTyr_kinase_cat_dom

ZAP70 FLT1

3.95e-0388202IPR020635
DomainPROTEIN_KINASE_TYR

ZAP70 FLT1

4.77e-0397202PS00109
DomainTyr_kinase_AS

ZAP70 FLT1

4.77e-0397202IPR008266
DomainPkinase_Tyr

ZAP70 FLT1

8.29e-03129202PF07714
DomainSer-Thr/Tyr_kinase_cat_dom

ZAP70 FLT1

9.44e-03138202IPR001245
Pubmed

Self-regulated alternative splicing at the AHNAK locus.

AHNAK PRX AHNAK2

1.90e-10321321940993
Pubmed

Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers.

AHNAK PRX CNTN1

1.06e-071621321745462
Pubmed

Hmg4, a new member of the Hmg1/2 gene family.

HMGB1 HMGB3

3.47e-0722129598312
Pubmed

The AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells.

AHNAK AHNAK2

3.47e-07221215007166
Pubmed

AHNAK1 and AHNAK2 are costameric proteins: AHNAK1 affects transverse skeletal muscle fiber stiffness.

AHNAK AHNAK2

3.47e-07221220833135
Pubmed

ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.

LARS1 RNF213 AHNAK AHNAK2 STAU1

4.81e-0726821533024031
Pubmed

CUL4A-mediated ZEB1/microRNA-340-5p/HMGB1 axis promotes the development of osteoporosis.

HMGB1 ZEB1

1.04e-06321237253097
Pubmed

Bioinformatics analysis of the prognosis and biological significance of HMGB1, HMGB2, and HMGB3 in gastric cancer.

HMGB1 HMGB3

1.04e-06321231621076
Pubmed

AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration.

AHNAK AHNAK2

2.08e-06421217185750
Pubmed

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.

KDM2B KMT2C KDM5D

3.43e-064921334368113
Pubmed

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses.

HMGB1 HMGB3

3.47e-06521219890330
Pubmed

New nomenclature for chromatin-modifying enzymes.

KDM2B KMT2C KDM5D

5.44e-065721318022353
Pubmed

SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action.

AHNAK AHNAK2

7.28e-06721223415230
Pubmed

Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS.

HMGB1 HMGB3 STAU1

9.27e-066821336966392
Pubmed

Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling.

ZAP70 ZEB1

9.70e-0682128176201
Pubmed

Human transcription factor protein interaction networks.

LARS1 KDM2B HMGB1 KMT2C HMGB3 ZEB1 STAU1

1.36e-05142921735140242
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

LARS1 PON2 RNF213 HMGB1 AHNAK AHNAK2 STAU1

1.43e-05144021730833792
Pubmed

A novel cell-cell junction system: the cortex adhaerens mosaic of lens fiber cells.

AHNAK PRX

1.90e-051121214625392
Pubmed

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.

KMT2C KDM5D

2.70e-051321224619213
Pubmed

TBX1 targets the miR-200-ZEB2 axis to induce epithelial differentiation and inhibit stem cell properties.

FLT1 ZEB1

4.15e-051621236418889
Pubmed

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.

HMGB1 HMGB3 AHNAK PRX

4.19e-0533021421044950
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

LARS1 RNF213 AHNAK AHNAK2

4.29e-0533221432786267
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

LARS1 HMGB1 HMGB3 ATP4A HMGB1P1 STAU1

4.64e-05115321629845934
Pubmed

A transposon in Comt generates mRNA variants and causes widespread expression and behavioral differences among mice.

SLC12A6 STAU1

4.70e-051721220808911
Pubmed

Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality.

PON2 DLX5

6.55e-052021216341224
Pubmed

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

KDM2B KMT2C

7.24e-052121227626377
Pubmed

HMGB factors are required for posterior digit development through integrating signaling pathway activities.

HMGB1 HMGB3

7.96e-052221221384471
Pubmed

A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity.

ZAP70 ZEB1

8.72e-052321222761313
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

LARS1 HMGB1 AHNAK AHNAK2 STAU1

9.93e-0580721530575818
Pubmed

A chemical tool for blue light-inducible proximity photo-crosslinking in live cells.

AHNAK STAU1

1.03e-042521235211260
Pubmed

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.

LARS1 HMGB1 AHNAK AHNAK2

1.09e-0442221427342126
Pubmed

Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition.

FLT1 ZEB1

1.21e-042721227178982
Pubmed

Isolation and characterization of proteins associated with histone H3 tails in vivo.

HMGB1 KMT2C

1.50e-043021217403666
Pubmed

Dlx1&2-dependent expression of Zfhx1b (Sip1, Zeb2) regulates the fate switch between cortical and striatal interneurons.

DLX5 ZEB1

1.60e-043121223312518
Pubmed

Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening.

AHNAK ZEB1

1.60e-043121232546759
Pubmed

Interaction proteomics of the HMGA chromatin architectural factors.

HMGB1 HMGB3

1.70e-043221218850631
Pubmed

Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.

KDM2B KDM5D

1.81e-043321226864203
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

HMGB1 HMGB3 AHNAK HMGB1P1 STAU1

2.17e-0495421536373674
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

LARS1 HMGB3 AHNAK AHNAK2

2.75e-0453821428524877
Pubmed

N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.

SLC12A6 KMT2C AHNAK

2.93e-0421721334048709
Pubmed

Proteome analysis of the HIV-1 Gag interactome.

LARS1 STAU1

3.24e-044421225010285
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

LARS1 HMGB1 KMT2C HMGB3 STAU1

4.23e-04110321534189442
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

SLC12A6 HMGB1 ATP4A CNTN1

4.73e-0462121422794259
Pubmed

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers.

HMGB1 AHNAK AHNAK2

4.92e-0425921331162944
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

LARS1 HMGB1 HMGB3 AHNAK STAU1

5.10e-04114921535446349
Pubmed

Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation.

LARS1 HMGB1 AHNAK

5.61e-0427121326816005
Pubmed

Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription.

KMT2C AHNAK2

5.82e-045921228813667
Pubmed

A cellular and spatial map of the choroid plexus across brain ventricles and ages.

FLT1 CNTN1

5.82e-045921233932339
InteractionLHX2 interactions

KDM2B HMGB1 KMT2C HMGB3 STAU1

1.06e-06183215int:LHX2
InteractionAHNAK interactions

HMGB1 ATP4A AHNAK PRX STAU1

1.57e-05318215int:AHNAK
InteractionGJB7 interactions

AHNAK CNTN1 AHNAK2

2.61e-0556213int:GJB7
InteractionAGR2 interactions

LARS1 HMGB1 ATP4A ZAP70 AHNAK AHNAK2 STAU1

2.95e-05934217int:AGR2
InteractionFEV interactions

KDM2B KMT2C HMGB3 ZEB1

5.23e-05203214int:FEV
InteractionHNF1A interactions

KDM2B HMGB1 KMT2C

7.61e-0580213int:HNF1A
InteractionISG15 interactions

LARS1 RNF213 AHNAK AHNAK2 STAU1

1.27e-04494215int:ISG15
InteractionPRX interactions

AHNAK PRX

1.57e-0418212int:PRX
InteractionATP6V1A interactions

LARS1 PON2 ATP4A STAU1

1.58e-04270214int:ATP6V1A
InteractionLHX1 interactions

KDM2B KMT2C STAU1

1.61e-04103213int:LHX1
InteractionDNAAF2 interactions

HMGB1 ATP4A CNTN1

1.61e-04103213int:DNAAF2
InteractionEN1 interactions

KDM2B KMT2C ZEB1

1.96e-04110213int:EN1
InteractionTERF2IP interactions

KDM2B HMGB1 HMGB3 PRX ZEB1

2.14e-04552215int:TERF2IP
InteractionJSRP1 interactions

AHNAK AHNAK2

2.15e-0421212int:JSRP1
InteractionH3C1 interactions

KDM2B HMGB1 KMT2C HMGB3 AHNAK STAU1

2.39e-04901216int:H3C1
InteractionSP7 interactions

KDM2B KMT2C DLX5 STAU1

2.48e-04304214int:SP7
InteractionFOS interactions

KDM2B HMGB1 KMT2C ZEB1

2.74e-04312214int:FOS
InteractionGTPBP1 interactions

LARS1 ZEB1 STAU1

2.79e-04124213int:GTPBP1
InteractionPAX7 interactions

KDM2B KMT2C ZEB1

2.79e-04124213int:PAX7
InteractionSUMO2 interactions

LARS1 RNF213 AHNAK HMGB1P1 AHNAK2

2.94e-04591215int:SUMO2
InteractionFLT3 interactions

LARS1 PON2 RNF213 STAU1

2.94e-04318214int:FLT3
InteractionKLF8 interactions

KDM2B HMGB1 ZEB1 STAU1

3.35e-04329214int:KLF8
Cytoband13q12

HMGB1 FLT1

5.47e-052421213q12
CytobandEnsembl 112 genes in cytogenetic band chr7q21

PON2 DLX5

2.99e-03178212chr7q21
CytobandEnsembl 112 genes in cytogenetic band chr13q12

HMGB1 FLT1

5.10e-03234212chr13q12
CytobandEnsembl 112 genes in cytogenetic band chr20q13

HMGB1P1 STAU1

1.58e-02422212chr20q13
GeneFamilyCanonical high mobility group

HMGB1 HMGB3

6.36e-0511202511
GeneFamilyPHD finger proteins

KDM2B KMT2C KDM5D

1.28e-049020388
GeneFamilyPHD finger proteins|Lysine demethylases

KDM2B KDM5D

3.16e-0424202485
GeneFamilyPDZ domain containing

AHNAK PRX AHNAK2

5.98e-041522031220
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

FLT1 CNTN1

1.35e-02161202593
GeneFamilyImmunoglobulin like domain containing

FLT1 CNTN1

1.90e-02193202594
CoexpressionSU_PLACENTA

HMGB3 FLT1 DLX5

1.77e-0630213M6349
CoexpressionGSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN

SLC12A6 KMT2C ZEB1 STAU1

1.71e-05198214M8624
CoexpressionSWEET_LUNG_CANCER_KRAS_DN

FLT1 AHNAK PRX ZEB1 CNTN1

1.74e-05422215M7396
CoexpressionSWEET_LUNG_CANCER_KRAS_DN

FLT1 AHNAK PRX ZEB1 CNTN1

2.22e-05444215MM1051
CoexpressionCUI_TCF21_TARGETS_2_DN

PON2 SLC12A6 KMT2C FLT1 AHNAK PRX

4.19e-05854216M1533
CoexpressionCUI_TCF21_TARGETS_2_DN

PON2 SLC12A6 KMT2C FLT1 AHNAK PRX

5.21e-05888216MM1018
CoexpressionLAKE_ADULT_KIDNEY_C23_ENDOTHELIAL_CELLS_AVR

FLT1 AHNAK ZEB1

1.35e-04126213M39242
CoexpressionRUBENSTEIN_SKELETAL_MUSCLE_ENDOTHELIAL_CELLS

HMGB1 FLT1 AHNAK

1.73e-04137213M41743
CoexpressionLAKE_ADULT_KIDNEY_C24_ENDOTHELIAL_CELLS_AEA_AND_DVR

FLT1 AHNAK ZEB1

2.36e-04152213M39243
CoexpressionMARSON_FOXP3_TARGETS_STIMULATED_UP

KDM2B ZAP70

2.62e-0430212M3146
CoexpressionMARSON_FOXP3_TARGETS_STIMULATED_UP

KDM2B ZAP70

2.62e-0430212MM728
CoexpressionGSE4984_UNTREATED_VS_VEHICLE_CTRL_TREATED_DC_DN

LARS1 PON2 HMGB1

3.50e-04174213M6501
CoexpressionGSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_DN

RNF213 AHNAK AHNAK2

3.68e-04177213M7632
CoexpressionGSE27291_0H_VS_7D_STIM_GAMMADELTA_TCELL_DN

SLC12A6 KDM2B KMT2C

4.53e-04190213M8457
CoexpressionFIGUEROA_AML_METHYLATION_CLUSTER_3_DN

AHNAK AHNAK2

4.68e-0440212M2169
CoexpressionGSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_UP

LARS1 FLT1 AHNAK

4.96e-04196213M3203
CoexpressionGSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_UP

SLC12A6 AHNAK KDM5D

5.03e-04197213M3133
CoexpressionGSE26351_UNSTIM_VS_BMP_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_DN

RNF213 HMGB1 FLT1

5.18e-04199213M8481
CoexpressionGSE14769_40MIN_VS_360MIN_LPS_BMDM_DN

KMT2C ZEB1 KDM5D

5.18e-04199213M3517
CoexpressionGSE42021_TREG_VS_TCONV_PLN_DN

AHNAK CNTN1 AHNAK2

5.18e-04199213M9574
CoexpressionGSE37532_WT_VS_PPARG_KO_LN_TCONV_UP

SLC12A6 KMT2C AHNAK2

5.26e-04200213M8954
CoexpressionGSE40273_GATA1_KO_VS_WT_TREG_DN

KDM2B KMT2C ZEB1

5.26e-04200213M9133
CoexpressionGSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY15_EFFECTOR_CD8_TCELL_UP

SLC12A6 RNF213 FLT1

5.26e-04200213M9522
CoexpressionGSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP

PON2 AHNAK2 STAU1

5.26e-04200213M6057
CoexpressionGSE42021_CD24HI_VS_CD24INT_TREG_THYMUS_UP

AHNAK CNTN1 AHNAK2

5.26e-04200213M9584
CoexpressionHOLLMANN_APOPTOSIS_VIA_CD40_UP

HMGB1 HMGB3 KDM5D

5.49e-04203213M9695
CoexpressionPARENT_MTOR_SIGNALING_DN

SLC12A6 CNTN1

5.67e-0444212M16644
CoexpressionFIGUEROA_AML_METHYLATION_CLUSTER_1_DN

AHNAK AHNAK2

6.19e-0446212M2161
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

RNF213 FLT1 AHNAK PRX ZEB1

2.42e-0820020572ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

RNF213 FLT1 AHNAK PRX ZEB1

2.42e-082002055c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

RNF213 FLT1 PRX ZEB1

1.19e-061822047af3b2029b7f55b923d5a4b764d4292f4ea48599
ToppCellE18.5-samps-Endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

RNF213 FLT1 PRX ZEB1

1.19e-06182204e2d799e6e7526176a6fe6515b8fbe4d83d3a3ea1
ToppCellControl-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

PON2 FLT1 PRX ZEB1

1.27e-06185204a28187c2fd23564314b35759479ff2ca21f61485
ToppCellControl-Endothelial-VE_Capillary_A|Control / Disease state, Lineage and Cell class

PON2 FLT1 PRX ZEB1

1.33e-0618720454d7588172ac145ff5045ad9771636729ca3f0ca
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RNF213 KMT2C ZAP70 AHNAK

1.48e-0619220447646d7e4990be85072987f92bf18d52f8da752e
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PON2 FLT1 PRX ZEB1

1.51e-06193204ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PON2 FLT1 PRX ZEB1

1.51e-06193204aaf681f16f310168e4719464814a1fc0a2f8431a
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PON2 FLT1 PRX ZEB1

1.54e-0619420440842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCellCOVID-19-lung-Capillary_Aerocytes|COVID-19 / Disease (COVID-19 only), tissue and cell type

PON2 FLT1 PRX ZEB1

1.60e-0619620449cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCellCOVID-19-lung-Capillary_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

PON2 FLT1 PRX ZEB1

1.60e-06196204ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCellCOVID-19-lung-Capillary_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PON2 FLT1 PRX ZEB1

1.67e-0619820445419f2804b4be79bae6632e71c54e1af482d115
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HMGB1 HMGB3 DLX5 CNTN1

1.70e-0619920459915b6db86fd0cc83a0bf9a3a1dda08522ec8d3
ToppCellcellseq-Endothelial-Endothelial_Vascular|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PON2 FLT1 PRX ZEB1

1.70e-06199204307d29816a224193aa3d8c4540e128b2ad2e90b9
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RNF213 FLT1 PRX ZEB1

1.74e-06200204a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

RNF213 KMT2C FLT1 ZEB1

1.74e-06200204dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellLPS_IL1RA_TNF-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RNF213 FLT1 PRX ZEB1

1.74e-06200204d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

RNF213 FLT1 PRX ZEB1

1.74e-06200204edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

RNF213 AHNAK PRX ZEB1

1.74e-0620020479e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellBiopsy_Control_(H.)-Endothelial-Endothelial_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

PON2 FLT1 PRX ZEB1

1.74e-062002040242d465da2dfba0da629a43e152949c5192465b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 PRX ZEB1

4.72e-05159203d3f81ba22160568ccaa6d2b04ebfd30630f9a6db
ToppCellControl-Endothelial_cells-Inflamed_endothelial_cells|Control / group, cell type (main and fine annotations)

FLT1 PRX ZEB1

4.81e-05160203958256e3d3836160763b82bb48f794087918d935
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 PRX ZEB1

5.18e-051642031592a5becad7e0f3f990f0d7581d75fcfc7da023
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

FLT1 PRX ZEB1

5.47e-051672035af9127bae05768a5164d5708a4ad37edca99324
ToppCellLA-16._Neuronal|World / Chamber and Cluster_Paper

AHNAK PRX CNTN1

5.56e-051682032fd1fd2a16ac1c5eb028f93cc3a2477c7747693e
ToppCellLA-16._Neuronal|LA / Chamber and Cluster_Paper

AHNAK PRX CNTN1

5.56e-05168203c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 PRX ZEB1

5.66e-05169203987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122|Adult / Lineage, Cell type, age group and donor

FLT1 PRX ZEB1

5.86e-05171203bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 PRX ZEB1

6.07e-05173203f193c63cc536d891c9d23043765e320252bb6e65
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 PRX ZEB1

6.07e-05173203afa6bb19df52541d8d17cbfac9cbdd18a5f3632d
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high|PND01-03-samps / Age Group, Lineage, Cell class and subclass

FLT1 PRX ZEB1

6.17e-05174203cb0109661e8c9ca04d67d33f2d926f0e649bf67d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 PRX ZEB1

6.39e-05176203dc5a22f9d1347f157bdd93e6e5769b983deccf1a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 PRX ZEB1

6.39e-0517620364e426f5e84884ce2c29acf6f4b958962a63927f
ToppCellfacs-Skin-Anagen-3m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAP70 ZEB1 CNTN1

6.50e-051772037853430fb0d1a18d835e8956777e0616c5d7d412
ToppCellfacs-Skin-Anagen-3m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAP70 ZEB1 CNTN1

6.50e-05177203395f005f019aabb18738d3a10a04c37f216deda3
ToppCellfacs-Skin-Anagen-3m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAP70 ZEB1 CNTN1

6.50e-051772039a5bf67a801826d094f679dd2189b62296c9694f
ToppCellE17.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLT1 PRX ZEB1

6.61e-05178203982205ba117a4c7b7e9b713689a5b69190f0bca9
ToppCellEndothelial-A-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

FLT1 ZEB1 AHNAK2

6.72e-05179203138fd6ba6bdbd0ad01c574168addf720b67a0fea
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|367C / Donor, Lineage, Cell class and subclass (all cells)

PON2 FLT1 PRX

6.83e-05180203162cec1734e560c068cd61717e40e18dcf92308c
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLT1 PRX ZEB1

6.83e-05180203d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

FLT1 PRX ZEB1

6.83e-05180203b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|367C / Donor, Lineage, Cell class and subclass (all cells)

PON2 FLT1 PRX

6.83e-0518020333c86c22ba877358cd8c1e39b5c0b3dc3a45b7dd
ToppCellLPS-IL1RA-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AHNAK PRX ZEB1

6.83e-05180203544fb373a3346186ec60afe2cfcf141bb04a1eed
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

FLT1 PRX ZEB1

6.94e-05181203c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HMGB1 HMGB3 DLX5

6.94e-05181203f2ebeb4941510c4b6e50f2379c574d1778d6ced1
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FLT1 PRX ZEB1

7.06e-05182203a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_A|E18.5-samps / Age Group, Lineage, Cell class and subclass

RNF213 PRX ZEB1

7.06e-05182203ea4f6c8f600ffe9f8e0609637b3371a5ac48ca03
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

FLT1 PRX ZEB1

7.06e-05182203fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175|Adult / Lineage, Cell type, age group and donor

FLT1 PRX ZEB1

7.06e-051822038b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCellIPF-Myeloid-DC_Langerhans|World / Disease state, Lineage and Cell class

PON2 FLT1 ZEB1

7.06e-051822030e8cfbd8ea196f27a227dbb4d2eb93bc48d27922
ToppCellIPF-Myeloid-DC_Langerhans|IPF / Disease state, Lineage and Cell class

PON2 FLT1 ZEB1

7.41e-05185203f8ee3cb2aa9ec70f9ce8797be2b155da27ef6464
ToppCellIPF-Myeloid-DC_Langerhans|Myeloid / Disease state, Lineage and Cell class

PON2 FLT1 ZEB1

7.41e-05185203ced17f69486591c3cbbdc852a3e82c3f3a4a30d7
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZAP70 ZEB1 KDM5D

7.41e-05185203f1263899a2d41d182022dc4ca62cbae08a463c89
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMH+-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

RNF213 AHNAK KDM5D

7.41e-05185203097d628f92e13250c15b550f2fd1f4225fc07558
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D231|Adult / Lineage, Cell type, age group and donor

FLT1 PRX ZEB1

7.41e-0518520307f9f38f0739d7c830641723a38385550ac1ac92
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT1 ZEB1 AHNAK2

7.41e-05185203fa94c4a1660967f211ba095606cd0aa37d38e17a
ToppCellControl-Endothelial_cells-Endothelial_cells_(other)|Control / group, cell type (main and fine annotations)

FLT1 PRX ZEB1

7.53e-05186203c6075fe84226b370c5139066793844ad33ae2db1
ToppCell343B-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PON2 FLT1 PRX

7.53e-05186203080e56113b89138277a2bd2eabddfa6cd1a18b61
ToppCell343B-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PON2 FLT1 PRX

7.53e-05186203dae6a98963c78bf7518ebab8dc02f173c3b0f7f7
ToppCell3'-Adult-Appendix-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT1 ZEB1 AHNAK2

7.65e-05187203ec98d5e480b08854dfd0ba6b1dc6610455f90640
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLT1 PRX ZEB1

7.65e-0518720397b2463fb37e7196dd2f92553acf8e7bc3ec40dd
ToppCellEndothelial-A-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

FLT1 ZEB1 AHNAK2

7.65e-05187203fd93f3f4b82dae3bf4eef245bfedc2a9e3251b61
ToppCellP15-Endothelial-unknown_endothelial_cell-endothelial_unknown_1|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PON2 FLT1 PRX

7.65e-0518720360f41b1f1b656d211b80398aa2cf0ac0cdad9372
ToppCellControl-Endothelial_cells-Endothelial_cells_(general)|Control / group, cell type (main and fine annotations)

FLT1 PRX ZEB1

7.65e-05187203fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT1 ZEB1 AHNAK2

7.65e-0518720337d8ee5c8bd6324749e5a2adef1d0482c75da80c
ToppCellP15-Endothelial-unknown_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PON2 FLT1 PRX

7.65e-05187203d543ddc63f864b6d0982c4ff652af174af085c4a
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RNF213 PRX ZEB1

7.65e-05187203f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Adult / Lineage, Cell type, age group and donor

FLT1 PRX ZEB1

7.77e-05188203e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D122|Adult / Lineage, Cell type, age group and donor

FLT1 PRX ZEB1

7.77e-0518820302a62888e9db29d20133eeca1686d302545a39c9
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-cycling_neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HMGB1 HMGB3 DLX5

7.77e-0518820333afe31b1093d317dc38c324197c6e91bf6c39d3
ToppCellControl-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

PON2 FLT1 PRX

7.77e-0518820388b3415e33db81726dd29c1f50c886e057af50a0
ToppCellControl-Endothelial_cells|Control / group, cell type (main and fine annotations)

FLT1 PRX ZEB1

7.77e-051882033953b08abfea93468fc8d177bdb16ca7c6ffa1ab
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNF213 ZAP70 AHNAK

7.89e-051892030e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCellIPF-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

FLT1 PRX ZEB1

7.89e-05189203ea3aa3ef38f1d405bb527ae383cd12c551a3dd6f
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FLT1 PRX ZEB1

7.89e-05189203b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellPND07-28-samps-Endothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

FLT1 PRX ZEB1

7.89e-05189203eb2f8c8a90e5e9f6697a2d13274c94f40e1973e4
ToppCellNon-neuronal-Non-dividing-OPC|World / Primary Cells by Cluster

PON2 ZEB1 CNTN1

7.89e-0518920313848a031ab896b4b24c8319e4745b9b17ff9cfd
ToppCellNon-neuronal-Non-dividing-OPC-OPC|World / Primary Cells by Cluster

PON2 ZEB1 CNTN1

7.89e-05189203ddf5be73912570c32c50f4ac2902da9b590526f8
ToppCellNon-neuronal-Non-dividing-OPC-OPC-30|World / Primary Cells by Cluster

PON2 ZEB1 CNTN1

7.89e-05189203313d165fad541ec6e8dd524b88856e2c93eeb681
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

FLT1 PRX ZEB1

7.89e-05189203d4a25d59d88325d3b20f4287e9b1160c82961a96
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FLT1 PRX ZEB1

8.02e-051902030a351609a72fd638c84b2435782e312ee6a33aac
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

FLT1 PRX ZEB1

8.02e-051902035130fb325f80f591b9b36beacb8072c4472304f2
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(general)|COVID-19 / group, cell type (main and fine annotations)

FLT1 PRX ZEB1

8.02e-05190203812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

PON2 FLT1 PRX

8.02e-051902037f3f419fffe02934b6f27b697f7a6401072491ed
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

DLX5 CNTN1 KDM5D

8.02e-0519020362a3ec1ae0829602b0569cc051210551644f1d46
ToppCellPND01-03-samps-Endothelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

FLT1 PRX ZEB1

8.02e-051902031357bd4527399d7013ee33272bda7453f472999a
ToppCellIPF-Endothelial-VE_Capillary_A|IPF / Disease state, Lineage and Cell class

FLT1 PRX ZEB1

8.02e-05190203b4e35cbfe4d43d2cd51f29c3085e4d9b1012e6f0
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FLT1 PRX ZEB1

8.02e-051902030e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

FLT1 PRX ZEB1

8.14e-05191203f229abf69a1217194f74b0502486907e07dba989
ToppCellControl-Endothelial-VE_Capillary_B|Control / Disease state, Lineage and Cell class

PON2 PRX ZEB1

8.14e-05191203322237793a1278bafb14e63cab688b353e352dcc
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLT1 PRX ZEB1

8.14e-051912031de0bdfd13bd930691564c2673f2e66393bc0255
ToppCellControl-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

PON2 PRX ZEB1

8.14e-05191203c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCellE17.5-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HMGB1 HMGB3 FLT1

8.14e-05191203efe0cb0b6602621f5eda72a723b83b38bf15607f
ToppCellE17.5-Endothelial-proliferative_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HMGB1 HMGB3 FLT1

8.14e-0519120300676c598f6dae0ff9158d064248f1265432f3e1
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT1 PRX ZEB1

8.14e-05191203a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT1 PRX ZEB1

8.27e-05192203c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCellCOPD-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

PON2 FLT1 ZEB1

8.27e-05192203984cdc2f1d93e164bc946d63f58dacb629f82eb7
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PON2 FLT1 PRX

8.27e-05192203aedddccacf60e884af044cefba6c64ca10ac97d2
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMH+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RNF213 ZAP70 KDM5D

8.27e-05192203fdc741e1846cfd8ed741b160e3c611c310c5d36d
Diseaserheumatoid arthritis (implicated_via_orthology)

KMT2C ZAP70

3.17e-0512212DOID:7148 (implicated_via_orthology)
DiseaseKawasaki disease (is_marker_for)

HMGB1 FLT1

4.37e-0514212DOID:13378 (is_marker_for)
DiseaseSezary Syndrome

KMT2C ZEB1

1.68e-0427212C0036920
Diseaseamyotrophic lateral sclerosis (is_implicated_in)

PON2 HMGB1

2.36e-0432212DOID:332 (is_implicated_in)
DiseaseVasodilators used in cardiac diseases use measurement

RNF213 FLT1

2.67e-0434212EFO_0009926
Diseasenasopharynx carcinoma (is_marker_for)

KMT2C FLT1

4.28e-0443212DOID:9261 (is_marker_for)
DiseaseAlzheimer disease, age at onset

LARS1 AHNAK DLX5

1.77e-03343213EFO_0004847, MONDO_0004975
Diseasehypertrophic cardiomyopathy

KMT2C AHNAK

1.94e-0392212EFO_0000538
DiseaseSquamous cell carcinoma of esophagus

HMGB1 KMT2C

2.07e-0395212C0279626
Diseaseangina pectoris

RNF213 FLT1

3.55e-03125212EFO_0003913

Protein segments in the cluster

PeptideGeneStartEntry
LKGPKFKMPEMNIKV

AHNAK

801

Q09666
EGKLKGPKFKMPEMN

AHNAK

926

Q09666
GPKFKMPEMNIKAPK

AHNAK

931

Q09666
IKMPKFSMPSLKGEG

AHNAK

1001

Q09666
PEGKLKGPKFKMPEM

AHNAK

1046

Q09666
GKLKGPKFKMPEMHF

AHNAK

1176

Q09666
DAKLKGPKFKMPEMS

AHNAK

1431

Q09666
PKVKMPKFSMPGFKG

AHNAK

1511

Q09666
KLKGPKFKMPSMNIQ

AHNAK

1561

Q09666
PDAKLKGPKFKMPDM

AHNAK

1901

Q09666
KGPKFKMPDMHFKAP

AHNAK

1906

Q09666
KLKGPKFKMPEMHFK

AHNAK

1971

Q09666
KGPKLKMPEMHFKAP

AHNAK

2101

Q09666
KLKGPKFKMPEMHFK

AHNAK

2166

Q09666
MKMPKFSMPGFKGEG

AHNAK

2246

Q09666
PEGKLKGPKFKMPEM

AHNAK

2291

Q09666
KLKGPKLKMPEMNIK

AHNAK

2561

Q09666
PEGKLKGPKFKMPEM

AHNAK

2686

Q09666
KGPKFKMPEMNIKAP

AHNAK

2691

Q09666
LKGPKFKMPEMNIKA

AHNAK

2946

Q09666
EGKLKGPKFKMPEMN

AHNAK

3071

Q09666
GPKFKMPEMNIKAPK

AHNAK

3076

Q09666
KLKGPKFKMPEMNIK

AHNAK

3201

Q09666
MPDLDLNLKGPKMKG

AHNAK

3221

Q09666
LKGPKFKMPDMNIKA

AHNAK

3526

Q09666
DAKLKGPKFKMPEMN

AHNAK

3651

Q09666
GPKFKMPEMNIKAPK

AHNAK

3656

Q09666
KVKMPKFSMPGFKGE

AHNAK

3806

Q09666
LKGPKFKMPEMNIKA

AHNAK

3856

Q09666
DAKLKGPKFKMPEMN

AHNAK

3981

Q09666
GPKFKMPEMNIKAPK

AHNAK

3986

Q09666
PKVKMPKFSMPGFKG

AHNAK

4061

Q09666
MPEVDLNLKGPKMKG

AHNAK

4131

Q09666
PDAKLKGPKFKMPEM

AHNAK

4236

Q09666
KGPKFKMPEMNIKAP

AHNAK

4241

Q09666
AKLKGPKFKMPEMNI

AHNAK

4366

Q09666
KLKGPKFKMPEMNIK

AHNAK

4441

Q09666
DAKLKGPKFKMPEMS

AHNAK

4701

Q09666
PKVKMPKFSMPGFKG

AHNAK

4781

Q09666
KIKKIMKNGEMPPEH

DLX5

191

P56178
FKDKTMLCPMHKPKG

KMT2C

4496

Q8NEZ4
MGKGDPKKPRGKMSS

HMGB1

1

P09429
PGPKMMGLGLMAKDK

KDM5D

241

Q9BY66
KPGGILMMDLKEEKP

PON2

81

Q15165
KDMKKFGGPGRMKQS

KDM2B

631

Q8NHM5
EMNPMKKKILAAKGG

CNTN1

416

Q12860
KMAAEAGKKQPGMKP

BPIFB6

46

Q8NFQ5
MAKGDPKKPKGKMSA

HMGB3

1

O15347
KKKPTKTPQMGTFMG

SLC12A6

176

Q9UHW9
PGPGGDMAAKMSKKK

ATP4A

16

P20648
YMMPAKGKKTDKQPL

LARS1

916

Q9P2J5
MGKGDPKKPRGKMSS

HMGB1P1

1

B2RPK0
MPKVALKGPQMDVKG

AHNAK2

1751

Q8IVF2
GKEMKEKTQRMKQPP

RNF213

286

Q63HN8
GQKPYKKMKGPEVMA

ZAP70

536

P43403
CMKLGKKPMYKPVDP

STAU1

81

O95793
EFGFKMPKMTMPKLG

PRX

796

Q9BXM0
PPKKKMRKTENGMYA

ZEB1

891

P37275
KKEKMEPGLEQGKKP

FLT1

941

P17948