Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

MYCL ZNF675 ZNF93 ZNF676 IKZF2 ZNF486 ZFHX4 MYT1 ZNF429 NLRC5 ZNF778 ZNF217 PRDM5 ZNF681 ZNF114

3.61e-0512447315GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

MYCL ZNF675 ZNF93 ZNF676 IKZF2 ZNF486 ZFHX4 MYT1 ZNF429 NLRC5 ZNF778 ZNF217 PRDM5 ZNF681 ZNF114

4.62e-0512717315GO:0000987
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

MYCL ZNF675 ZNF93 ZNF676 IKZF2 ZNF486 ZFHX4 MYT1 ZNF429 OSR2 NLRC5 ZNF778 ZNF217 PRDM5 ZNF681 ZNF114

5.96e-0514597316GO:0000977
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

MYCL ZNF675 ZNF93 ZNF676 ZNF486 ZFHX4 MYT1 ZNF429 OSR2 ZNF778 ZNF217 PRDM5 SP110 ZNF681 ZNF114

1.51e-0414127315GO:0000981
GeneOntologyMolecularFunctionnerve growth factor binding

A2M PCSK6

3.64e-048732GO:0048406
GeneOntologyMolecularFunctionzinc ion binding

ZNF675 TET2 ZNF93 TRIM67 ZFHX4 MID2 MYT1 SF3A3 ZSWIM2 TRIM22 ZMYM6

3.71e-048917311GO:0008270
GeneOntologyMolecularFunctionneurotrophin binding

A2M PCSK6

8.50e-0412732GO:0043121
DomainZnf_C2H2-like

ZNF675 ZNF93 ZNF676 IKZF2 ZNF486 ZFHX4 SF3A3 ZNF429 OSR2 ZNF778 ZNF217 PRDM5 ZNF681 ZNF687 ZNF114

2.91e-077967215IPR015880
Domainzf-C2H2_6

ZNF675 ZNF93 ZNF676 ZNF486 ZNF429 OSR2 ZNF778 PRDM5 ZNF681 ZNF114

3.34e-073147210PF13912
Domainzf-C2H2

ZNF675 ZNF93 ZNF676 IKZF2 ZNF486 ZFHX4 ZNF429 OSR2 ZNF778 ZNF217 PRDM5 ZNF681 ZNF687 ZNF114

3.35e-076937214PF00096
DomainZnf_C2H2

ZNF675 ZNF93 ZNF676 IKZF2 ZNF486 ZFHX4 SF3A3 ZNF429 OSR2 ZNF778 ZNF217 PRDM5 ZNF681 ZNF687 ZNF114

3.36e-078057215IPR007087
DomainZnf_C2H2/integrase_DNA-bd

ZNF675 ZNF93 ZNF676 IKZF2 ZNF486 ZFHX4 ZNF429 OSR2 ZNF778 ZNF217 PRDM5 ZNF681 ZNF687 ZNF114

3.41e-076947214IPR013087
DomainZnF_C2H2

ZNF675 ZNF93 ZNF676 IKZF2 ZNF486 ZFHX4 SF3A3 ZNF429 OSR2 ZNF778 ZNF217 PRDM5 ZNF681 ZNF687 ZNF114

3.53e-078087215SM00355
DomainZINC_FINGER_C2H2_2

ZNF675 ZNF93 ZNF676 IKZF2 ZNF486 ZFHX4 ZNF429 OSR2 ZNF778 ZNF217 PRDM5 ZNF681 ZNF687 ZNF114

1.27e-067757214PS50157
DomainZINC_FINGER_C2H2_1

ZNF675 ZNF93 ZNF676 IKZF2 ZNF486 ZFHX4 ZNF429 OSR2 ZNF778 ZNF217 PRDM5 ZNF681 ZNF687 ZNF114

1.31e-067777214PS00028
Domain-

ZNF675 ZNF93 ZNF676 IKZF2 ZNF486 ZFHX4 ZNF429 OSR2 ZNF778 ZNF217 PRDM5 ZNF681 ZNF114

1.70e-0667972133.30.160.60
DomainKRAB

ZNF675 ZNF93 ZNF676 ZNF486 ZNF429 ZNF778 ZNF681 ZNF114

6.93e-05358728PS50805
DomainKRAB

ZNF675 ZNF93 ZNF676 ZNF486 ZNF429 ZNF778 ZNF681 ZNF114

8.55e-05369728SM00349
DomainKRAB

ZNF675 ZNF93 ZNF676 ZNF486 ZNF429 ZNF778 ZNF681 ZNF114

8.72e-05370728IPR001909
DomainFolate_rcpt

FOLR3 IZUMO1R

1.45e-045722IPR004269
DomainSPRY

TRIM67 MID2 TRIM22 RYR3

3.55e-0487724SM00449
DomainFolate_rcpt-like

FOLR3 IZUMO1R

4.04e-048722IPR018143
DomainFolate_rec

FOLR3 IZUMO1R

4.04e-048722PF03024
DomainKRAB

ZNF675 ZNF93 ZNF486 ZNF429 ZNF778 ZNF681 ZNF114

4.53e-04358727PF01352
DomainSPRY

TRIM67 MID2 TRIM22 RYR3

4.76e-0494724PF00622
DomainSPRY_dom

TRIM67 MID2 TRIM22 RYR3

4.76e-0494724IPR003877
DomainB30.2/SPRY

TRIM67 MID2 TRIM22 RYR3

4.96e-0495724IPR001870
DomainB302_SPRY

TRIM67 MID2 TRIM22 RYR3

4.96e-0495724PS50188
DomainCOS_domain

TRIM67 MID2

9.43e-0412722IPR017903
DomainCOS

TRIM67 MID2

9.43e-0412722PS51262
DomainBbox_C

TRIM67 MID2

1.49e-0315722IPR003649
DomainBBC

TRIM67 MID2

1.49e-0315722SM00502
DomainConA-like_dom

TRIM67 MID2 WDFY3 TRIM22 RYR3

1.57e-03219725IPR013320
Domainzf-C3HC4

TRIM67 MID2 RNF213 ZSWIM2 TRIM22

1.70e-03223725PF00097
Domain-

TRIM67 MID2 RNF213 ZSWIM2 WDFY3 SP110 TRIM22

1.70e-034497273.30.40.10
DomainZnf_RING/FYVE/PHD

TRIM67 MID2 RNF213 ZSWIM2 WDFY3 SP110 TRIM22

1.92e-03459727IPR013083
DomainBBOX

TRIM67 MID2 TRIM22

2.40e-0369723SM00336
Domain-

TRIM67 MID2 TRIM22

2.60e-03717234.10.45.10
Domainzf-B_box

TRIM67 MID2 TRIM22

2.71e-0372723PF00643
DomainZF_BBOX

TRIM67 MID2 TRIM22

3.65e-0380723PS50119
DomainZnf_B-box

TRIM67 MID2 TRIM22

3.78e-0381723IPR000315
DomainZnf_C3HC4_RING-type

TRIM67 MID2 RNF213 TRIM22

4.39e-03172724IPR018957
DomainZF_RING_2

TRIM67 MID2 RNF213 ZSWIM2 TRIM22

5.86e-03298725PS50089
DomainRING

TRIM67 MID2 RNF213 ZSWIM2 TRIM22

6.45e-03305725SM00184
DomainZnf-RING_LisH

MID2 TRIM22

7.59e-0334722IPR027370
Domainzf-RING_UBOX

MID2 TRIM22

7.59e-0334722PF13445
Pubmed

Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.

ZNF93 ZNF429 ZNF778 ZNF681

8.43e-08207342542606
Pubmed

Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.

ZNF93 ZNF429 ZNF778 ZNF681

8.43e-08207347479878
Pubmed

Comparative analysis of KRAB zinc finger proteins in rodents and man: evidence for several evolutionarily distinct subfamilies of KRAB zinc finger genes.

ZNF93 ZNF429 ZNF681

7.38e-07973310360839
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

RESF1 ZFHX4 SH3TC1 WDR6 PCSK6 RNF213 WDFY3 RFC2 PRDM5 CMAS SP110 ZNF687

3.40e-061116731231753913
Pubmed

Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.

ZNF93 ZNF429 ZNF681

3.96e-061573315885501
Pubmed

Tagging genes with cassette-exchange sites.

ZNF93 RESF1 ZNF429 AKAP13 PRDM5 BIRC6 ZNF681

6.83e-0633573715741177
Pubmed

Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci.

ZNF93 ZNF429 ZNF778 ZNF681

8.51e-06617348662221
Pubmed

Selective reprogramming of regulatory T cells in solid tumors can strongly enhance or inhibit tumor growth.

FOLR3 IZUMO1R

1.30e-05373237928524
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

WDR6 DHX40 TAF1B SF3A3 AKAP13 DGKD WDFY3 RFC2 CMAS BIRC6 CCDC93 KIF2C

2.34e-051353731229467282
Pubmed

Identification of two putative novel folate receptor genes in humans and mouse.

FOLR3 IZUMO1R

2.60e-05473211111049
Pubmed

Proteomic analysis of FOXP proteins reveals interactions between cortical transcription factors associated with neurodevelopmental disorders.

ZFHX4 EMSY ZNF687

2.80e-052873329365100
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TET2 RESF1 ZFHX4 WDR6 ZNF217 BIRC6 ZNF687

2.84e-0541873734709266
Pubmed

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.

ZNF93 ZNF429 ZNF681

3.12e-052973314563677
Pubmed

A pair of mouse KRAB zinc finger proteins modulates multiple indicators of female reproduction.

ZNF93 ZNF429

4.33e-05573220042539
Pubmed

The KRAB zinc finger protein RSL1 modulates sex-biased gene expression in liver and adipose tissue to maintain metabolic homeostasis.

ZNF93 ZNF429

4.33e-05573224190968
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

MYCL ZNF93 IKZF2 ZC3H13 MYT1 ZNF429 PRDM5 ZNF681 ZNF687

4.85e-0580873920412781
Pubmed

Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding.

TRIM67 MID2

6.48e-05673216434393
Pubmed

Degree of predicted minor histocompatibility antigen mismatch correlates with poorer clinical outcomes in nonmyeloablative allogeneic hematopoietic cell transplantation.

AKAP13 SP110

6.48e-05673220353833
Pubmed

The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons.

ZNF93 ZNF429

6.48e-05673230846446
Pubmed

A whole genome screen for HIV restriction factors.

ZNF93 NLRC5 DGKD SPAG16

8.12e-0510873422082156
Pubmed

The KRAB zinc finger protein RSL1 regulates sex- and tissue-specific promoter methylation and dynamic hormone-responsive chromatin configuration.

ZNF93 ZNF429

9.06e-05773222801370
Pubmed

Interaction network of human early embryonic transcription factors.

TET2 RESF1 ZFHX4 WDR6 ZNF217 EMSY

9.76e-0535173638297188
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

RESF1 DHX40 EMSY ZNF687 KIF2C

1.07e-0422273537071664
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

MYCL IKZF2 MYT1 PCSK6 OSR2 ZNF217 BIRC6 ZNF687

1.20e-0470973822988430
Pubmed

Spatial and temporal expression of folate-related transporters and metabolic enzymes during mouse placental development.

FOLR3 IZUMO1R

1.21e-04873222365888
Pubmed

Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.

ZNF429 ZNF778 ZNF681

1.52e-04497339630514
Pubmed

Transcriptional mechanisms of EphA7 gene expression in the developing cerebral cortex.

IKZF2 EPHA5

2.36e-041173221940705
Pubmed

Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling.

A2M UNC5C EPHA5

2.65e-045973331351040
Pubmed

Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions.

DONSON TRIM22 ZNF687

3.53e-046573317567994
Pubmed

Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC.

RASIP1 WDR6

3.89e-041473222354037
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

AKAP13 BIRC6 RYR3 CCDC93

4.41e-0416873430631154
Pubmed

In the developing cerebral cortex: axonogenesis, synapse formation, and synaptic plasticity are regulated by SATB2 target genes.

UNC5C EPHA5

4.48e-041573236028553
Pubmed

Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation.

ZNF486 IQCH TAF1B AKAP13 KIF2C

4.63e-0430573521244100
Pubmed

Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.

ZNF93 ZNF114

5.12e-04167328467795
Pubmed

Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice.

ZFHX4 WDFY3

5.12e-041673216096065
Pubmed

Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells.

IKZF2 ZNF217 RFC2 KIF2C

5.48e-0417873427637333
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF93 ZNF486 ZNF778 ZNF681

5.84e-0418173437372979
Pubmed

TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity.

MID2 TRIM22

6.51e-041873223077300
Pubmed

Development of the prethalamus is crucial for thalamocortical projection formation and is regulated by Olig2.

UNC5C EPHA5

6.51e-041873224803655
Pubmed

TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity.

MID2 TRIM22

7.26e-041973226347139
Pubmed

Zfhx4 regulates endochondral ossification as the transcriptional platform of Osterix in mice.

ZFHX4 OSR2

7.26e-041973234732852
Pubmed

KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.

SF3A3 CMAS

8.06e-042073233995658
Pubmed

ISL1 and POU4F1 Directly Interact to Regulate the Differentiation and Survival of Inner Ear Sensory Neurons.

MYT1 EPHA5

8.06e-042073238267260
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

ZNF675 CFAP47 ESRP2 ZC3H13 RNF213 AKAP13 BIRC6

8.98e-0473673729676528
Pubmed

Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS.

UNC5C EPHA5

1.07e-032373224360543
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TET2 RESF1 RNF213

1.28e-0310173310997877
Pubmed

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.

TET2 EMSY

1.47e-032773223395962
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

RESF1 DHX40 ZNF217 EMSY ZMYM6 KIF2C

1.49e-0358873638580884
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

TET2 RESF1 ZFHX4 ZNF217 C9orf72

1.52e-0339873535016035
CytobandEnsembl 112 genes in cytogenetic band chr19p12

ZNF675 ZNF93 ZNF676 ZNF486 ZNF429 ZNF681

4.58e-08122736chr19p12
Cytoband19p12

ZNF675 ZNF93 ZNF676 ZNF486 ZNF681

3.50e-079073519p12
Cytoband13q14.13

ZC3H13 RUBCNL

6.17e-042373213q14.13
Cytoband2q34

IKZF2 SPAG16

9.18e-04287322q34
CytobandEnsembl 112 genes in cytogenetic band chr1p34

MYCL SF3A3 ZMYM6 KIF2C

1.27e-03294734chr1p34
CytobandEnsembl 112 genes in cytogenetic band chr2q34

IKZF2 SPAG16

2.36e-0345732chr2q34
Cytoband1p34.2

MYCL ZMYM6

3.76e-03577321p34.2
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF675 ZNF93 ZNF676 IKZF2 ZNF486 ZNF429 OSR2 ZNF778 ZNF217 PRDM5 ZNF681 ZNF114

1.04e-06718541228
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

RESF1 AKAP13 SP110 TRIM22

1.60e-0551544870
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TET2 RESF1 RNF213 AKAP13 SP110 BIRC6 TRIM22

3.92e-0820073712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ESRP2 PCSK6 ZNF778 KEL RFC2 RYR3

3.43e-071687368f0c4dfad9f6fed9dcc31795abfe77758ceb46a1
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|368C / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 SH3TC1 RNF213 METTL8 ZMYM6 CCDC93

5.31e-07181736b193f3606554adc55c5906219d114288bb1f978a
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX4 UNC5C ADCY8 RYR3 EPHA5

6.60e-06160735c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX4 UNC5C ADCY8 RYR3 EPHA5

6.60e-0616073525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellmetastatic_Brain-Myeloid_cells-pDCs|metastatic_Brain / Location, Cell class and cell subclass

RASIP1 SH3TC1 SP110 TRIM22 KIF2C

7.44e-0616473506db4cc064f0765c481ce880207823872c27bfa9
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-B_cells-Pre-B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IKZF2 RUBCNL NLRC5 SP110 TRIM22

1.08e-05177735ecd26d086c1aff3be442fcb055611a563ca034ef
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

RASIP1 MID2 RNF213 NXPE2 NRROS

1.23e-051827357af3b2029b7f55b923d5a4b764d4292f4ea48599
ToppCellE18.5-samps-Endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

RASIP1 MID2 RNF213 NXPE2 NRROS

1.23e-05182735e2d799e6e7526176a6fe6515b8fbe4d83d3a3ea1
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

NLRC5 RNF213 ZNF217 SP110 TRIM22

1.27e-051837358f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TET2 PALS1 UNC5C PRDM5 RYR3

1.27e-05183735eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 SH3TC1 RNF213 ZMYM6 CCDC93

1.40e-05187735689b3cc76f1e04bd35a7d3ce19e9f08744a7835b
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 SH3TC1 RNF213 ZMYM6 CCDC93

1.40e-051877354527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCellFetal_29-31_weeks-Immune-B_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IKZF2 RUBCNL NLRC5 DGKD SP110

1.52e-05190735424550418c1bd4eb070cf3c41cf09fa9d89aef37
ToppCellFetal_29-31_weeks-Immune-B_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IKZF2 RUBCNL NLRC5 DGKD SP110

1.56e-0519173584452125d1b5b76974e3f9126f611eff16d45c25
ToppCellPBMC-Mild|PBMC / Compartment, Disease Groups and Clusters

TET2 RNF213 NRROS SP110 TRIM22

1.68e-05194735d1366b169d14011194e61d16b6b0953349febc78
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

A2M IKZF2 RESF1 NLRC5 RNF213

1.80e-05197735836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

A2M IKZF2 NLRC5 RNF213 TRIM22

1.89e-05199735f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellmild-MAIT|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

A2M IKZF2 RESF1 RNF213 TRIM22

1.89e-05199735cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

RASIP1 RESF1 RNF213 NRROS TRIM22

1.94e-05200735bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RASIP1 RESF1 RNF213 NRROS TRIM22

1.94e-0520073589821a264e872ed53e08e9d3609d5cc5c314503e
ToppCellVE|World / Condition, Cell_class and T cell subcluster

RESF1 RNF213 AKAP13 SP110 TRIM22

1.94e-052007358ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RASIP1 RESF1 RNF213 NRROS TRIM22

1.94e-05200735a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCellLPS_IL1RA_TNF-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RASIP1 RESF1 RNF213 NRROS TRIM22

1.94e-05200735d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

RASIP1 RESF1 RNF213 NRROS TRIM22

1.94e-05200735432384faeade8e609154fab3d96c955a8ec868dd
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

A2M RESF1 NLRC5 RNF213

4.69e-0512173419333a660800b583fa27b495c1f7828e6636a257
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZFHX4 ZC3H12B RYR3 ZNF687

5.84e-051287342cf0384240a4a663869cf6b27d954236f6214a9a
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DONSON RIMOC1 OSR2 CCDC93

8.27e-051407340e1e9281de87df178ac41ed6b697b4fa09be2749
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M UNC5C TRPV2 KEL

1.08e-041507348645b9c7f9511ed6cc9afe04440c2873a3094150
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-8|TCGA-Bladder / Sample_Type by Project: Shred V9

MYCL ZNF675 ZNF217 ZNF681

1.08e-041507341aa9320d97ff10994ea024751790524fe133aba9
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ESRP2 RASIP1 SH3TC1 NXPE2

1.20e-04154734b0735365de153d4586ca17896431d7bd9c7d8eac
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK|Thalamus / BrainAtlas - Mouse McCarroll V32

RASIP1 SH3TC1 NXPE2 SP110

1.23e-04155734fe6c4aba0e98cda84bf178aeac2e9fa834477f22
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NLRC5 RNF213 NRROS SP110

1.39e-0416073418954241e11309ecb0f3ca87897eadcb20dc8eca
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_STALK|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RASIP1 SH3TC1 NXPE2 SP110

1.39e-0416073404714d0b9bad4c11fa193ed168e2d84a4df39e2e
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 RESF1 NLRC5 PRDM5

1.45e-041627344b9f80f701dcbb2508f497095cb8a7a2ca51cb5e
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

A2M WDR6 RNF213 KEL

1.45e-04162734f0a92c92c3a6cf9fa11fb279a584e7f328cb7d43
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IKZF2 DONSON IZUMO1R SRSF12

1.49e-041637344af92b211d12c5b88b65bb746242cd702b545bd0
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IKZF2 DONSON IZUMO1R SRSF12

1.49e-04163734d24774e0aa612322c22fdb3b314aef275fa01d68
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

A2M GPD1L RASIP1 ZC3H13

1.56e-041657345e7ee76f3dcddbd1b560bacd043f9001b0c18b5f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

A2M RESF1 NLRC5 ZNF687

1.60e-041667349e916fc1858573358e1eb5e3789b2c9f8ef74476
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M RASIP1 SH3TC1 OR10W1

1.79e-04171734b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK6 PXYLP1 CCDC93 KIF2C

1.83e-04172734dd9ba79e1542fe9fa2c319077d83dd3fc0158f46
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

RASIP1 ZNF676 ZFHX4 PCSK6

1.87e-04173734a81992965137195d20fc498f750975303961a828
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-B_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RUBCNL TRPV2 NLRC5 TRIM22

1.91e-041747341b2a2129c08bac01fc638692313b196759a1e0d7
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MLIP TRIM22 RYR3 EPHA5

1.91e-04174734e4d65fe121a32ac4cdd6312e7b8f867f0852e991
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M RASIP1 ZSWIM2 NRROS

1.91e-0417473442735f6a8e5ec36dd3d35aceea6d37cf3eaa1871
ToppCellmetastatic_Brain-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

MYCL RUBCNL NLRC5 ZNF114

1.91e-041747345ec8a48a390379d6c422120dce46437a77da67cc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-B_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RUBCNL TRPV2 NLRC5 TRIM22

1.91e-041747345bde24eb588dc588efc413811379548120ec0c7f
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNF213 SP110 TRIM22 ZNF114

1.95e-0417573497616bb5c127284aa9e67bc336dfcf29e137164b
ToppCellEndothelial-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

RASIP1 ZNF676 ZFHX4 NXPE2

2.00e-04176734b288116a4588a1f9db9d49af92cea118937c9201
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRIM67 PCSK6 DGKD ADCY8

2.00e-04176734682a1dfcc507ec540f5fadf08e872533ea9f0291
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MLIP TRIM22 RYR3 EPHA5

2.04e-041777344c069f0d044a96118090b85ca592a21d6b5d9399
ToppCellBAL-Control-cDC_1|Control / Compartment, Disease Groups and Clusters

RNF213 SP110 TRIM22 ZNF114

2.04e-04177734aa021f6d62e9d740c5ea499faaf875de835a2865
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-B_cells-Pre-B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IKZF2 RUBCNL SP110 TRIM22

2.08e-041787348545c0238d8d833a6a179872d44bfb739310ea17
ToppCellrenal_papilla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

IKZF2 ZFHX4 PXYLP1 NYAP1

2.17e-0418073449829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCellwk_20-22-Hematologic-Meg-ery-Platelet|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RESF1 ZNF778 KEL RYR3

2.22e-04181734724efbc200e8388829bc7d81830c2689a95fa838
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_A|E18.5-samps / Age Group, Lineage, Cell class and subclass

RASIP1 MID2 RNF213 NXPE2

2.27e-04182734ea4f6c8f600ffe9f8e0609637b3371a5ac48ca03
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

A2M IKZF2 RNF213 DGKD

2.32e-04183734f593a89b0aa8fffdfa403769916facfd30358521
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PALS1 UNC5C PRDM5 RYR3

2.32e-041837343c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALS1 UNC5C PRDM5 RYR3

2.32e-04183734612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PALS1 UNC5C PRDM5 RYR3

2.32e-041837349c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellCF-Myeloid-Neutrophil|CF / Disease state, Lineage and Cell class

RESF1 RUBCNL ZNF429 C9orf72

2.32e-04183734da43827952e6fdee2ce94648c316182f272b321c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M ZFHX4 RYR3 EPHA5

2.36e-041847342cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M ZFHX4 RYR3 EPHA5

2.36e-04184734ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M ZFHX4 RYR3 EPHA5

2.36e-041847342b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PALS1 UNC5C PRDM5 RYR3

2.36e-041847347294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PALS1 UNC5C PRDM5 RYR3

2.41e-041857349197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PALS1 UNC5C PRDM5 RYR3

2.41e-04185734ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ZFHX4 UNC5C ZNF217

2.41e-04185734e1fbec55b71f604189eb2431768fadbaa0453a83
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ZFHX4 UNC5C ZNF217

2.41e-041857349d933cd5ebc8368fd37aa83113d2dfa6938ff72d
ToppCellsaliva-Severe-critical_progression_d28-40|saliva / Compartment, severity and other cell annotations on 10x 3' data (130k)

TET2 PALS1 RUBCNL WDFY3

2.46e-041867340095560ca776b01aa473ad4d6015ed78fc93ff51
ToppCell5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-B_cells-Pro-B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IKZF2 SH3TC1 NLRC5 TRIM22

2.46e-041867344a5264e32ba004ed58dc4102d84e4bc4dbbe1440
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells-Memory_B|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1 RUBCNL SP110 TRIM22

2.46e-04186734b5e094850ac3785775393cd78a939b02339732b0
ToppCell5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-B_cells|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IKZF2 SH3TC1 NLRC5 TRIM22

2.46e-04186734528ee88f6e27863c7bcdffd4416cbbd83fc65e9d
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RASIP1 NLRC5 RNF213 TRIM22

2.51e-04187734f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCell3'_v3-blood-Lymphocytic_T_CD8-Trm/em_CD8|blood / Manually curated celltypes from each tissue

A2M RESF1 NLRC5 RNF213

2.57e-0418873421730497f95dc271e4cdfaaf1da8b9ac6eec2ded
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

A2M ZFHX4 MID2 UNC5C

2.57e-04188734116ca07ee4413dcc0e9e5ac99bfee6ed7b7847c6
ToppCellwk_15-18-Hematologic_Lymphocytic-B-small_pre-B-II_cell|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

IKZF2 RUBCNL NLRC5 TRIM22

2.57e-0418873456d78b5a86a71b2e752db379f4a46dc4c623b553
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRIM67 RUBCNL DGKD ADCY8

2.57e-0418873472cbfe9dc0583dbeafa6cb0945fa370d0c808284
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

WDR6 NYAP1 EPHA5 SRSF12

2.57e-04188734b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRIM67 RUBCNL DGKD ADCY8

2.57e-041887348de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRIM67 RUBCNL DGKD ADCY8

2.62e-0418973478cf414b98bcb19deb934409acddaad1cd51b67f
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TET2 FOLR3 AKAP13 C9orf72

2.62e-0418973455aba1ebc012006a5db3ff9c92589cb3d9f7c68a
ToppCellwk_20-22-Hematologic_Lymphocytic-B-small_pre-B-II_cell|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

IKZF2 RUBCNL NLRC5 TRIM22

2.67e-04190734f49ceda3622cf079cffde9c9a9e3d0380c571d39
ToppCell(1)_T_cells-(1)_T_CD4_fh|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

RESF1 SH3TC1 AKAP13 METTL8

2.67e-04190734120ca702600373c208a3d032fede0a040736e5cf
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

NLRC5 RNF213 SP110 TRIM22

2.72e-041917342da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-cDC1|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYCL RUBCNL TRPV2 TRIM22

2.72e-041917349774d423e448ec2d415261e4ad386a81558129b3
ToppCellCV-Healthy-6|CV / Virus stimulation, Condition and Cluster

IKZF2 NLRC5 SP110 TRIM22

2.83e-041937341e285c31823d3e1a18d8c01748cc3604f400c954
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MLIP ZFHX4 PCSK6 OSR2

2.89e-041947340e315c63407fa00643722a7d6138b1502f79b10d
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M TET2 SH3TC1 AKAP13

2.89e-04194734449ce4167d64c170d914e0250f739eabedcf915d
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MLIP ZFHX4 PCSK6 OSR2

2.89e-04194734c2990d6eda3954dc01913bf3910df79f06e0010a
ToppCellCOVID-19_Moderate-CD8+_T_activated|World / disease group, cell group and cell class

IKZF2 NLRC5 RNF213 TRIM22

2.95e-04195734070c5d3bdbd4ea54a579c01c37fb99bcf823982e
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RESF1 RUBCNL C9orf72 SP110

3.01e-04196734fe8d3f45a64323947c36b127355d5940eb56c0ca
ToppCellhealthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

A2M RESF1 NLRC5 RNF213

3.01e-04196734af00c31612e4fe068e5fccae05368edba46bbd20
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RESF1 RUBCNL C9orf72 SP110

3.01e-04196734526d037bb12d81f1c235c60ddc787fbad0bbad77
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

A2M IKZF2 RNF213 AKAP13

3.01e-0419673417f17edadafdad9f24e88d708d7e1c765503131c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M RNF213 AKAP13 TRIM22

3.01e-04196734e54c08f88779f9fd453a4f5b85aed1f460d8a1e1
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

A2M IKZF2 NLRC5 RNF213

3.06e-04197734e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellsevere-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ZNF429 RNF213 SP110 TRIM22

3.06e-04197734c8a90d82170cf20e14aebecddcf7cc0ca56cda87
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_4|Classical_Monocyte / Disease condition and Cell class

FOLR3 RNF213 SP110 TRIM22

3.06e-04197734e666f6580e9a20b5e550f02125706db17eec8510
DiseaseOpitz GBBB syndrome (implicated_via_orthology)

TRIM67 MID2

8.75e-056722DOID:0080697 (implicated_via_orthology)
Diseasebeta-Ala-His dipeptidase measurement

ZNF675 ZNF681

1.63e-048722EFO_0008033
Diseasealpha-2-macroglobulin measurement

A2M TET2

1.63e-048722EFO_0020138
Diseaseage at menarche

TET2 IQCH ZFHX4 NXPE2 IZUMO1R ADCY8 EPHA5

6.15e-04594727EFO_0004703
Diseaseasthma, allergic disease

ZNF217 NRROS EMSY

9.64e-0479723MONDO_0004979, MONDO_0005271
Diseasecarnosine measurement

ZNF675 ZNF681

1.57e-0324722EFO_0010470
Diseaseeye measurement

RASIP1 AKAP13

1.98e-0327722EFO_0004731
Diseaseeosinophil count

TET2 IKZF2 RESF1 WDR6 MYT1 ZNF429 NLRC5 AKAP13 NRROS EMSY

3.20e-0314887210EFO_0004842
Diseasemultiple sclerosis

TET2 IKZF2 NLRC5 AKAP13 NRROS ADCY8

3.30e-03594726MONDO_0005301
DiseasePapillary Renal Cell Carcinoma

TET2 UNC5C AKAP13

3.82e-03128723C1306837
DiseaseRenal Cell Carcinoma

TET2 UNC5C AKAP13

3.82e-03128723C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

TET2 UNC5C AKAP13

3.82e-03128723C1266043
DiseaseChromophobe Renal Cell Carcinoma

TET2 UNC5C AKAP13

3.82e-03128723C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

TET2 UNC5C AKAP13

3.82e-03128723C1266044
Diseasecolorectal cancer, endometrial neoplasm

TET2 ZNF429

4.75e-0342722EFO_0004230, MONDO_0005575

Protein segments in the cluster

PeptideGeneStartEntry
LPEPRQDHAHCCVEM

ADCY8

471

P40145
RHHVPQQCNKMPITA

BIRC6

3666

Q9NR09
NMIHETNEHTLPKCR

BLOC1S5

81

Q8TDH9
SCVNHSVTDEPPKMH

EPHA5

261

P54756
ERDLCQVSHPHTKLM

AKAP13

2681

Q12802
KSFVHLEPMSHELPC

A2M

456

P01023
ACNKLSHPMVAIPEH

MLIP

436

Q5VWP3
RHCTVRAGPEHPAMV

RASIP1

436

Q5U651
DHPPCQLDIRLMRHK

RUBCNL

36

Q9H714
TPEAVNIFPKHHMCL

IQCH

536

Q86VS3
HKMTHNPNRPLAECQ

PRDM5

591

Q9NQX1
DVPPVMHVVCAQSHI

OR10W1

171

Q8NGF6
ICMNAKHHKRVPSPE

IZUMO1R

26

A6ND01
PVQEMLSCLQSHPEH

GPD1L

336

Q8N335
VPSQHMCVAASDKRP

PCSK6

496

P29122
VCMNAKHHKTQPSPE

FOLR3

36

P41439
HKTLHMQESPHKCPT

OSR2

246

Q8N2R0
HHVPPMEDCKEQEPI

IKZF2

236

Q9UKS7
IPCDMAQHLKSQEPR

NLRC5

1836

Q86WI3
PEEHQKHREMAVDCP

PALS1

26

Q8N3R9
RMKCPHQLEPHQIQG

CCDC93

96

Q567U6
SEEKMDHRVCPPLSH

DGKD

651

Q16760
MEVVHKELTNCGLHP

DONSON

521

Q9NYP3
PDVQHTQHPMVAKDR

EMSY

1016

Q7Z589
QCMPDHVIPEIKRTS

DHX40

416

Q8IX18
HNHRSCEEPVKDMLL

CFAP47

571

Q6ZTR5
HPLTMTDPIEEHRIC

KIF2C

246

Q99661
FSRMHCPTVPDEKNH

METTL8

141

Q9H825
DVNTVKQMPPCHEHI

C9orf72

311

Q96LT7
QNCLMTLHIREHEPP

NRROS

361

Q86YC3
ERELPNSHSMICPKA

NYAP1

421

Q6ZVC0
VRPQHMPCEALTHMT

NXPE2

256

Q96DL1
SPCLHPTDLQKVAEM

CMAS

146

Q8NFW8
PEILVKENNMHPKHC

RIMOC1

106

A6NDU8
NVPCDSEHMRPSKLA

RESF1

1471

Q9HCM1
NLPDEMHSLTCHVVK

TAF1B

316

Q53T94
HVNHPCTVEEEMSVP

NDUFV1

281

P49821
CPDHHVRVMTGPRDA

SH3TC1

216

Q8TE82
QDHHKRSPKPMCPLE

PXYLP1

436

Q8TE99
HMQHPSTCPARDLTV

ESRP2

166

Q9H6T0
FHEDCHIPPVEAKRM

SP110

556

Q9HB58
MKSKERHPCSPSDHR

SRSF12

96

Q8WXF0
PVLHCCMELAPRHKD

RNF213

696

Q63HN8
KRHEMVANPSVICSH

ZNF93

66

P35789
TARKFPTCPEHEMEN

TRIM67

296

Q6ZTA4
MEHHCPNARLPVLKD

ZFHX4

96

Q86UP3
HEMVEEPPVICSHFS

ZNF676

36

Q8N7Q3
ATPVEMHAVRNPHVC

ZNF778

241

Q96MU6
LFTELCHPPRHMTQK

WDFY3

31

Q8IZQ1
CHPPRHMTQKEQEEK

WDFY3

36

Q8IZQ1
VRADPLDPCMKHFHI

MYCL

191

P12524
NVPKDHPHIEVMRID

RYR3

1246

Q15413
HELPVSCVSMQPHKD

SPAG16

351

Q8N0X2
HCKSPHRHRMVVLEP

TRPV2

361

Q9Y5S1
DEPHPLLVKEMIQHC

RFC2

256

P35250
DPSTPSRLACHVMHL

WDR6

821

Q9NNW5
EMHSKPHRQLCRSPC

ZC3H12B

71

Q5HYM0
KRHEMVNEPPVMCSH

ZNF675

66

Q8TD23
PIVHKNIVCPTAMES

ZSWIM2

516

Q8NEG5
PHTQHKECQTDLPMP

ZMYM6

706

O95789
KRHRMVAEPPVICSH

ZNF681

66

Q96N22
KRHEMVDEPPVVCSH

ZNF429

66

Q86V71
NKHVLMQHRPTLCEP

ZNF217

81

O75362
SAHQRMHKNRPPHVC

ZNF687

721

Q8N1G0
RKHPNEICVPMSVEF

SF3A3

96

Q12874
VRHNNKEMLVDVPPH

MID2

636

Q9UJV3
ESCHSQMHRPIKVEP

TET2

971

Q6N021
RHEMIAKPPVVCSHF

ZNF486

76

Q96H40
MSPQEGQKRDVCEHH

TRIM22

86

Q8IYM9
LTRPVVLTMHHCADP

UNC5C

601

O95185
PHVTIEDAQHRKPMD

ZC3H13

1171

Q5T200
HEMRNHSKPTCRLVP

ZNF114

126

Q8NC26
MCRKPSPQDSHDTHS

KEL

681

P23276
CPHKDRIPPEILAMH

MYT1

466

Q01538