Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

FKBP15 PTPRC DCDC1 CLASP1 CLIP2 CENPE KTN1 PHACTR4 CEP57L1 MYH15 DMD CCDC181 CAP1 PHACTR1

1.79e-0610995714GO:0008092
GeneOntologyMolecularFunctionkinetochore binding

CLASP1 CENPE

1.19e-046572GO:0043515
GeneOntologyMolecularFunctionmicrotubule binding

DCDC1 CLASP1 CLIP2 CENPE CEP57L1 CCDC181

2.40e-04308576GO:0008017
GeneOntologyMolecularFunctiondystroglycan binding

CLASP1 DMD

5.19e-0412572GO:0002162
GeneOntologyMolecularFunctionphosphatidylinositol 3-kinase regulatory subunit binding

PIK3AP1 FAM83B

7.13e-0414572GO:0036312
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine phosphatase activity

PTPRC PTPRE

1.06e-0317572GO:0005001
GeneOntologyMolecularFunctiontransmembrane receptor protein phosphatase activity

PTPRC PTPRE

1.06e-0317572GO:0019198
GeneOntologyMolecularFunctionlamin binding

DMD AKAP8L

1.33e-0319572GO:0005521
GeneOntologyMolecularFunctiontubulin binding

DCDC1 CLASP1 CLIP2 CENPE CEP57L1 CCDC181

1.35e-03428576GO:0015631
GeneOntologyMolecularFunctionmicrotubule plus-end binding

CLASP1 CLIP2

1.78e-0322572GO:0051010
GeneOntologyMolecularFunctionactin binding

FKBP15 PHACTR4 MYH15 DMD CAP1 PHACTR1

2.38e-03479576GO:0003779
GeneOntologyCellularComponentmitotic spindle

DCDC1 CLASP1 CENPE CDC16 CNTRL

2.37e-04201585GO:0072686
GeneOntologyCellularComponentlamellipodium

STXBP2 PHACTR4 ALS2 CTNND1 DMD

4.40e-04230585GO:0030027
GeneOntologyCellularComponentmicrotubule

PARP4 DCDC1 CLASP1 CLIP2 CENPE CEP57L1 CCDC181

6.57e-04533587GO:0005874
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

PARP4 DCDC1 CLASP1 CLIP2 CENPE CEP57L1 KRT20 DMD CCDC181

7.74e-04899589GO:0099513
DomainRPEL

PHACTR4 PHACTR1

1.71e-047542PS51073
DomainRPEL

PHACTR4 PHACTR1

1.71e-047542PF02755
DomainRPEL

PHACTR4 PHACTR1

1.71e-047542SM00707
DomainRPEL_repeat

PHACTR4 PHACTR1

1.71e-047542IPR004018
DomainRCC1

ALS2 HERC5

1.51e-0320542PF00415
DomainRCC1_1

ALS2 HERC5

1.66e-0321542PS00625
DomainRCC1_2

ALS2 HERC5

1.66e-0321542PS00626
DomainRCC1_3

ALS2 HERC5

1.66e-0321542PS50012
DomainReg_chr_condens

ALS2 HERC5

1.83e-0322542IPR000408
Domain-

ALS2 HERC5

1.83e-03225422.130.10.30
DomainRCC1/BLIP-II

ALS2 HERC5

2.00e-0323542IPR009091
DomainPROTEIN_KINASE_TYR

CSF1R PEAK1 RYK

2.78e-0397543PS00109
DomainTyr_kinase_AS

CSF1R PEAK1 RYK

2.78e-0397543IPR008266
DomainPTPc

PTPRC PTPRE

4.85e-0336542SM00194
DomainTYR_PHOSPHATASE_PTP

PTPRC PTPRE

5.68e-0339542PS50055
DomainPTPase_domain

PTPRC PTPRE

6.26e-0341542IPR000242
DomainY_phosphatase

PTPRC PTPRE

6.26e-0341542PF00102
DomainZnf_C2H2-like

ZBTB17 ZNF277 ZNF507 ZNF407 ZNF236 AKAP8L ZUP1

7.70e-03796547IPR015880
DomainZnf_C2H2

ZBTB17 ZNF277 ZNF507 ZNF407 ZNF236 AKAP8L ZUP1

8.17e-03805547IPR007087
DomainZnF_C2H2

ZBTB17 ZNF277 ZNF507 ZNF407 ZNF236 AKAP8L ZUP1

8.33e-03808547SM00355
DomainVWA

PARP4 VWF

1.14e-0256542PF00092
PathwayREACTOME_ROLE_OF_ABL_IN_ROBO_SLIT_SIGNALING

CLASP1 CAP1

2.07e-048392M27351
PathwayREACTOME_MITOTIC_SPINDLE_CHECKPOINT

CLASP1 CENPE CDC16 AHCTF1

2.42e-04111394M27673
PathwayREACTOME_MITOTIC_SPINDLE_CHECKPOINT

CLASP1 CENPE CDC16 AHCTF1

2.96e-04117394MM15387
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

PHACTR4 EFR3B PEAK1 CTNND1 DMD AKAP8L GOLGB1 FAM83B

4.87e-0742158836976175
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

CLASP1 CLIP2 CDC16 UBR4 PEAK1 CTNND1 DMD

1.10e-0632258726514267
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

AHCTF1 KTN1 PHACTR4 EFR3B PEAK1 CTNND1 GOLGB1 CAP1 FAM83B

2.49e-0670858939231216
Pubmed

Myosin gene mutation correlates with anatomical changes in the human lineage.

MYH15 MYH16

2.73e-06258215042088
Pubmed

Immunomagnetic CD45 depletion does not improve cytokeratin 20 RT-PCR in colorectal cancer.

PTPRC KRT20

2.73e-06258217378731
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

STRAP PHF3 CDC16 AHCTF1 KTN1 PHACTR4 PEAK1 CTNND1

3.51e-0654958838280479
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RPGRIP1 SPAG1 STXBP2 ATRX KTN1 CNTRL UBR4 KRT20 MYH15 DMD AKAP8L GOLGB1

3.75e-061442581235575683
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

FKBP15 STRAP CLASP1 CLIP2 CENPE KTN1 UBR4 CTNND1 GOLGB1 PHACTR1

3.96e-06963581028671696
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

AHCTF1 EFR3B PEAK1 CTNND1 GOLGB1 FAM83B

5.14e-0626358634702444
Pubmed

Evolution of sarcomeric myosin heavy chain genes: evidence from fish.

MYH15 MYH16

8.19e-06358215014174
Pubmed

CLASPs prevent irreversible multipolarity by ensuring spindle-pole resistance to traction forces during chromosome alignment.

CLASP1 CENPE

8.19e-06358222307330
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

PTPRC ATRX AHCTF1 CNTRL CEP57L1 ZNF507 ALS2 PEAK1 GOLGB1 PHACTR1

1.11e-051084581011544199
Pubmed

A human MAP kinase interactome.

VWF CLIP2 KTN1 CNTRL KRT20 DMD GOLGB1

1.62e-0548658720936779
Pubmed

Evolutionary implications of three novel members of the human sarcomeric myosin heavy chain gene family.

MYH15 MYH16

1.64e-05458211919279
Pubmed

Human MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochores.

CENPE CDC16

1.64e-05458212686615
Pubmed

ADAM12 alleviates the skeletal muscle pathology in mdx dystrophic mice.

PTPRC DMD

1.64e-05458212414501
Pubmed

PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential.

PTPRE PHACTR4 PEAK1 CTNND1

1.90e-059458432062451
Pubmed

Essential roles for the Tec family kinases Tec and Btk in M-CSF receptor signaling pathways that regulate macrophage survival.

PTPRC CSF1R

2.72e-05558218523268
Pubmed

Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC.

CENPE CDC16

2.72e-05558210477750
Pubmed

Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.

CLASP1 CLIP2

2.72e-05558211290329
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

PIK3AP1 FKBP15 STRAP CLASP1 CENPE PHF3 KTN1 CTNND1

2.84e-0573358834672954
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ATRX AHCTF1 KTN1 UBR4 PHACTR4 EFR3B PEAK1 CTNND1 GOLGB1 HERC5 FAM83B

3.01e-051487581133957083
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ATRX CLASP1 ZNF277 PHF3 CDC16 AHCTF1 KTN1 AKAP8L GOLGB1 FAM83B IWS1

3.20e-051497581131527615
Pubmed

Development of a screening set for new (CAG/CTG)n dynamic mutations.

CSF1R PTPRE

4.08e-0565828786123
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

PTPRC ATRX CLASP1 PHF3 PHACTR4 ZNF507 AKAP8L IWS1

4.17e-0577458815302935
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

SPAG1 KTN1 PHACTR4 PEAK1 CTNND1 GOLGB1 FAM83B

4.22e-0556558725468996
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

ATRX CLASP1 CENPE ZNF507 PFDN1 GOLGB1 FAM83B

5.43e-0558858738580884
Pubmed

Phactrs 1-4: A family of protein phosphatase 1 and actin regulatory proteins.

PHACTR4 PHACTR1

5.71e-05758215107502
Pubmed

Identification and typing of members of the protein-tyrosine phosphatase gene family expressed in mouse brain.

PTPRC PTPRE

5.71e-0575821454056
Pubmed

Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases.

PTPRC PTPRE

5.71e-05758212376545
Pubmed

IL-7 receptor alpha+ CD3(-) cells in the embryonic intestine induces the organizing center of Peyer's patches.

PTPRC CSF1R

5.71e-05758210330270
Pubmed

CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages.

PTPRC CSF1R

5.71e-05758230538245
Pubmed

Different expression patterns of Phactr family members in normal and injured mouse brain.

PHACTR4 PHACTR1

5.71e-05758222766235
Pubmed

The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn).

PTPRC CTNND1

5.71e-05758212370829
Pubmed

Identification of novel protein tyrosine phosphatases of hematopoietic cells by polymerase chain reaction amplification.

PTPRC PTPRE

5.71e-0575821932742
Pubmed

Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages.

VWF CSF1R

7.60e-05858215616565
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

PIK3AP1 STXBP2 CENPE CNTRL PHACTR4 ZNF507 PFDN1 FAM83B

8.21e-0585358828718761
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CLASP1 PHF3 PHACTR4 ALS2 PEAK1 CTNND1 GOLGB1 FAM83B

8.76e-0586158836931259
Pubmed

Glucose metabolism controls monocyte homeostasis and migration but has no impact on atherosclerosis development in mice.

PTPRC CSF1R

9.77e-05958239424804
Pubmed

Msx1 and Msx2 are expressed in sub-populations of vascular smooth muscle cells.

VWF PTPRC

9.77e-05958218627106
Pubmed

Claudin-4 localization in epithelial ovarian cancer.

PHACTR4 CTNND1 GOLGB1

1.03e-045458336237976
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

FKBP15 CDC16 KTN1 UBR4 PEAK1 CTNND1 AKAP8L CAP1 PHACTR1

1.06e-04113958936417873
Pubmed

A generic approach for the purification of signaling complexes that specifically interact with the carboxyl-terminal domain of G protein-coupled receptors.

CLASP1 CLIP2 CTNND1

1.09e-045558318448421
Pubmed

VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.

FKBP15 CLASP1 UBR4 ALS2 CTNND1

1.20e-0428858523383273
Pubmed

Self-renewing resident arterial macrophages arise from embryonic CX3CR1(+) precursors and circulating monocytes immediately after birth.

PTPRC CSF1R

1.22e-041058226642357
Pubmed

Endocardially Derived Macrophages Are Essential for Valvular Remodeling.

PTPRC CSF1R

1.22e-041058230799229
Pubmed

Defining the membrane proteome of NK cells.

FKBP15 PARP4 PTPRC CLASP1 CENPE KTN1 CNTRL UBR4 GOLGB1

1.28e-04116858919946888
Pubmed

Absence of colony stimulation factor-1 receptor results in loss of microglia, disrupted brain development and olfactory deficits.

PTPRC CSF1R

1.49e-041158222046273
Pubmed

Gene expression analysis of myeloid and lymphoid lineage markers during mouse haematopoiesis.

PTPRC CSF1R

1.49e-041158216925795
Pubmed

c-kit+ cells minimally contribute cardiomyocytes to the heart.

VWF PTPRC

1.49e-041158224805242
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

FKBP15 ATRX STRAP AHCTF1 KTN1 CTNND1 GOLGB1 HERC5

1.53e-0493458833916271
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

ATRX CDC16 CCDC168 PHACTR1

1.82e-0416858430631154
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

SPAG1 CENPE UBR4 PUS7L

1.90e-0417058423314748
Pubmed

Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function.

VWF PTPRC

2.11e-041358229114040
Pubmed

Fli-1 is required for murine vascular and megakaryocytic development and is hemizygously deleted in patients with thrombocytopenia.

VWF CSF1R

2.46e-041458210981960
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

STRAP CLASP1 CENPE PHF3 KTN1 AKAP8L HERC5

2.62e-0475958735915203
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

ATRX STRAP KTN1 PFDN1 DMD CAP1

2.73e-0453858628524877
Pubmed

Cloning and characterization of PTP-K1, a novel nonreceptor protein tyrosine phosphatase highly expressed in bone marrow.

PTPRC PTPRE

3.23e-04165828875997
Pubmed

Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex.

PTPRC CSF1R

3.23e-041658225425146
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PTPRC PTPRE EFR3B PEAK1 CTNND1 DMD AKAP8L IWS1

3.36e-04104958827880917
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

VWF KTN1 PFDN1 AKAP8L GOLGB1

3.38e-0436058533111431
Pubmed

Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping.

ZNF407 ZNF236

3.66e-041758219690890
Pubmed

Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control.

CDC16 UBR4

3.66e-041758229033132
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

PARP4 ATRX CLASP1 CDC16 CTNND1 GOLGB1

4.14e-0458258620467437
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

PHACTR4 EFR3B PEAK1 CTNND1 DMD

4.17e-0437758538117590
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

STRAP CLASP1 CLIP2 PHF3 CDC16 AHCTF1 KTN1 CTNND1 AKAP8L

4.18e-04137158936244648
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

CENPE CDC16 AHCTF1 IWS1

4.25e-0421058416565220
Pubmed

Functional proteomics mapping of a human signaling pathway.

VWF PTPRC ATRX UBR4 CCDC181 GOLGB1

4.49e-0459158615231748
Pubmed

Phactr4 regulates neural tube and optic fissure closure by controlling PP1-, Rb-, and E2F1-regulated cell-cycle progression.

PHACTR4 PHACTR1

4.59e-041958217609112
Pubmed

A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication.

STXBP2 ZNF277 CDC16 UBR4

4.89e-0421858419460752
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

STRAP CLIP2 PHF3 AHCTF1 KTN1 CTNND1 AKAP8L

5.06e-0484758735850772
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

STRAP KTN1 UBR4 PFDN1 CTNND1

5.39e-0439958537536630
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

ATRX CLASP1 PEAK1 PHACTR1

6.07e-0423158416452087
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

STRAP CLASP1 CENPE CDC16 AHCTF1 PFDN1 AKAP8L FAM83B

6.34e-04115558820360068
Pubmed

Centrosome-related genes, genetic variation, and risk of breast cancer.

CLASP1 CDC16 CNTRL

6.72e-0410258320508983
Pubmed

p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas.

PTPRC CTNND1

6.76e-042358225523391
Pubmed

Yolk-sac-derived macrophages regulate fetal testis vascularization and morphogenesis.

PTPRC CSF1R

7.37e-042458224912173
Pubmed

PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.

CENPE CDC16 CNTRL AKAP8L

7.80e-0424758432989298
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

ATRX PHF3 CDC16 CTNND1 AKAP8L

8.37e-0444058534244565
Pubmed

Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.

PIK3AP1 CLIP2 GOLGB1

8.59e-0411158322558309
Pubmed

Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene.

PTPRC CTNND1

9.34e-042758223001562
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

SPAG1 KTN1 CNTRL PHACTR4 EFR3B KRT20

9.76e-0468658629987050
Pubmed

Phosphoproteomics screen reveals akt isoform-specific signals linking RNA processing to lung cancer.

ATRX IWS1

1.00e-032858224462114
Pubmed

Loss of Mafb and Maf distorts myeloid cell ratios and disrupts fetal mouse testis vascularization and organogenesis†.

PTPRC CSF1R

1.08e-032958234007995
Pubmed

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.

KTN1 EFR3B PEAK1 CTNND1 GOLGB1

1.09e-0346758530194290
Pubmed

Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays.

PTPRC CENPE

1.23e-033158214684825
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

ATRX STRAP CLASP1 ZNF277 UBR4 ALS2 PFDN1 AKAP8L

1.26e-03128458817353931
Pubmed

Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome.

CDC16 RYK

1.31e-033258220056645
Pubmed

Murine txk: a protein tyrosine kinase gene regulated by T cell activation.

CSF1R RYK

1.31e-03325827542761
Pubmed

Mitochondrial Raf1 Regulates Glutamine Catabolism.

SPAG1 PEAK1 AKAP8L CAP1

1.37e-0328858438496616
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PARP4 CLIP2 KTN1 ZNF407 PEAK1

1.39e-0349358515368895
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

STRAP AHCTF1 KTN1 PEAK1 CTNND1 GOLGB1 CAP1

1.39e-03100758734597346
Pubmed

Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions.

PTPRC CSF1R

1.40e-033358236922518
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

CLASP1 CENPE KTN1 CTNND1 AKAP8L

1.44e-0349758536774506
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

FKBP15 ATRX PHF3 CDC16 UBR4 CTNND1 IWS1

1.45e-03101458732416067
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

CLASP1 AHCTF1 KTN1 UBR4 CAP1

1.45e-0349858536634849
Pubmed

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

RABEPK RPGRIP1 CEP57L1 ALS2 DMD ZUP1

1.46e-0374258626871637
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

FKBP15 KTN1 CTNND1 GOLGB1 FAM83B

1.53e-0350458534432599
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

ATRX STRAP CDC16 UBR4 PFDN1 CCDC178 ZNF236 IWS1

1.55e-03132758832694731
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

PHF3 AHCTF1 PHACTR4 GOLGB1 CAP1

1.55e-0350658530890647
InteractionPTPRA interactions

PTPRC PTPRE PHACTR4 PEAK1 CTNND1 RYK

7.56e-06164586int:PTPRA
InteractionWWTR1 interactions

STRAP PHF3 CDC16 AHCTF1 KTN1 PHACTR4 PEAK1 CTNND1

2.65e-05422588int:WWTR1
InteractionSTX4 interactions

STXBP2 KTN1 PHACTR4 EFR3B PEAK1 CTNND1 GOLGB1 FAM83B

2.93e-05428588int:STX4
InteractionEPHA2 interactions

CSF1R PHACTR4 EFR3B PEAK1 CTNND1 DMD AKAP8L RYK GOLGB1 FAM83B

3.48e-057195810int:EPHA2
InteractionMTNR1B interactions

CLASP1 CDC16 UBR4 PEAK1 CTNND1

4.32e-05135585int:MTNR1B
InteractionAFDN interactions

PHACTR4 EFR3B PEAK1 CTNND1 RYK GOLGB1 FAM83B

4.61e-05333587int:AFDN
InteractionLAMP1 interactions

CLASP1 KTN1 UBR4 PHACTR4 EFR3B PEAK1 CTNND1 GOLGB1 FAM83B

8.63e-05644589int:LAMP1
GeneFamilyPhosphatase and actin regulators

PHACTR4 PHACTR1

2.18e-054352679
GeneFamilyMyosin heavy chains

MYH15 MYH16

3.76e-04153521098
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRC PTPRE

7.47e-0421352813
GeneFamilyReceptor Tyrosine Kinases|CD molecules

CSF1R RYK

2.71e-0340352321
GeneFamilyX-linked mental retardation|Angiotensin receptors

ATRX DMD

4.72e-0353352103
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

FKBP15 CENPE PHACTR4

5.10e-03181353694
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

ATRX CENPE KTN1 CEP57L1 ZNF507 ZNF407 DMD AKAP8L GOLGB1 IWS1

5.96e-066295710Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

ATRX PHF3 KTN1 CNTRL GOLGB1 IWS1

2.32e-07199586fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell11.5-Distal-Immune-Hematopoietic,_Macrophage|Distal / Age, Tissue, Lineage and Cell class

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE PHACTR1

2.32e-07199586dd61854de202c805100bad58f1ce08c3bd04bb58
ToppCellTracheal-10x5prime-Immune_Myeloid-Monocytic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE PHACTR1

2.39e-072005867076b0db66c8f90c8f9ccfbc8bc0dcc82b15e5f3
ToppCell11.5-Distal-Immune|Distal / Age, Tissue, Lineage and Cell class

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE PHACTR1

2.39e-07200586c9ed06ae7a8f5a88578c8269d762d8739ae79c7f
ToppCellBronchus_Control_(B.)-Immune-TX-MoAM-1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE PHACTR1

2.39e-07200586fe7f8b04067b6680b69c8523f0fa514ef97207e2
ToppCell11.5-Distal-Immune-Immune|Distal / Age, Tissue, Lineage and Cell class

PTPRC CSF1R STXBP2 PTPRE PHACTR1

3.84e-06181585193ee02f547a218b2fc13e1174ea4cff4f8a3450
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC ATRX PHF3 KTN1 CNTRL

4.16e-061845851154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

5.39e-06194585de9c7c602d886d0cd8bbd1d7e7744f84df951238
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

5.39e-0619458549441ca0a8fa34cb847fecbb4b809dd01d879ebb
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

5.39e-0619458516c6fcbd36d473b883fb5361caca86eb134767ab
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

5.52e-0619558501da7115e38c280fb0baff2032b62bdb609bad5e
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

5.66e-06196585b904f3a6d6a93e149f5a1b34b6adad5c7894754d
ToppCellBL-critical-LOC-Myeloid-Neutrophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PIK3AP1 PTPRC STXBP2 PTPRE PHACTR1

5.66e-06196585f64d7fed31e418c55fe946744d78c3cbecec9bbf
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

5.81e-06197585b4f6501c266328439cba4f174e594a6a04a252a1
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

5.81e-06197585c6e977adb1248957d31300312310e08238b64236
ToppCell3'-Broncho-tracheal-Immune_Myeloid|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3AP1 PTPRC CSF1R PTPRE PHACTR1

5.81e-06197585d568354aff89ac84dd06360f19100ef578a041ed
ToppCellcritical-Myeloid|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PIK3AP1 PTPRC STXBP2 PTPRE PHACTR1

5.95e-06198585a5807517f8ca93b77f49f5787fd9036178b8fc2a
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

5.95e-061985857015b9f5ead65937e056d746340d44d0655d6a3e
ToppCell15-Distal-Immune-Hematopoietic,_Macrophage|Distal / Age, Tissue, Lineage and Cell class

PIK3AP1 PTPRC CSF1R PTPRE PHACTR1

5.95e-061985850e4aa6c7d74c5b1bb26996df1be3d58f998d18ac
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

5.95e-0619858579c8ab15e73f727c5e110ab9eab3ccb5edf9f714
ToppCellTracheal-10x5prime-Immune_Myeloid-Monocytic-Monocyte_CD14|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PTPRC CSF1R STXBP2 PTPRE PHACTR1

5.95e-061985854ba72ba1f0cebc93053aae72d763c33e155b6fa4
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

5.95e-061985856edf6c547e8a3aa2b23df4662bf59ed38caa9e5e
ToppCellBAL-Severe-cDC_1|Severe / Compartment, Disease Groups and Clusters

PIK3AP1 PTPRC CSF1R PTPRE HERC5

6.10e-061995859f5750212b887f92761ade33fc6e108cd5275297
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

6.10e-06199585e12cea071e46436835cc22fe7badcbe878a1305b
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

6.10e-061995852ff5007b971c6fca9a9ef433e257739f0322a2a5
ToppCellcritical|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PIK3AP1 PTPRC STXBP2 PTPRE PHACTR1

6.10e-0619958516c55cb8a0e740342009965f0eddfb0ed2858fab
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIK3AP1 PTPRC CSF1R PTPRE PHACTR1

6.10e-061995855ceeed92f831d068ff4bb3994f420002338330e7
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PIK3AP1 FKBP15 PTPRC CSF1R STXBP2

6.10e-0619958522001aa733273e784051b7f750e07d99aaf7a225
ToppCellLPS_anti-TNF-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PIK3AP1 PTPRC STXBP2 CENPE PHACTR1

6.10e-0619958576aab03a51681f0ce3369887cf71a884b0998ec5
ToppCellkidney_cells-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

6.10e-061995850a9783808528bc4c6d797d849a9177330c8fb867
ToppCellLPS_anti-TNF-Hematopoietic_Myeloid-Granulocytic_cells|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PIK3AP1 PTPRC STXBP2 CENPE PHACTR1

6.10e-061995857227e6be56e9f333ee143e1418d22de32a4ca66a
ToppCellNS-critical|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PIK3AP1 PTPRC STXBP2 PTPRE PHACTR1

6.10e-06199585f7c14dc9a9e659f89352dccf8954d6cbada011ab
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PIK3AP1 PTPRC CSF1R PTPRE PHACTR1

6.25e-06200585700960201ae0df2c79e2907f5a0f95d73f8034fe
ToppCellParenchymal-10x5prime-Immune_Myeloid-Monocytic-Monocyte_CD16|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

6.25e-0620058583d9aa5b46ae7a71a258b2e44b3251f95bc9a1b7
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

6.25e-0620058547abc2ebf5d6575af59aa044b584acf63a463bbb
ToppCellBronchial-10x5prime-Immune_Myeloid-Monocytic-Monocyte_CD16|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

6.25e-06200585d39bf03817b76c9dfcbcd868341b51bb8601ea9b
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PTPRC ATRX PHF3 GOLGB1 HERC5

6.25e-0620058512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellParenchyma_COVID-19-Immune-TX-MoAM-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

6.25e-062005858fd88dfc6e08e0186fc0f061526ad98a3b00bc31
ToppCellBronchial-10x5prime-Immune_Myeloid-Monocytic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

6.25e-06200585d237cf947d6768b022d18211e14af4adb4990708
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PIK3AP1 SPAG1 PTPRC STXBP2 CENPE

6.25e-06200585fd1b6db3c62f5a205b769ba0e61433dae6285b67
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-BMP_responsible_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

6.25e-0620058526251ed8c7fa7e87973d6f59bd398c88ad025395
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Granulocytic_cells|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PIK3AP1 SPAG1 PTPRC STXBP2 CENPE

6.25e-062005850b7573ec4e9c67c7d11dd8f5011a70bade30e930
ToppCellParenchymal-10x5prime-Immune_Myeloid-Monocytic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PIK3AP1 PTPRC CSF1R STXBP2 PTPRE

6.25e-062005850855ebb10b925664aa5cf813d97e97683c46180d
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

UBR4 ZNF507 CCDC168 CCDC178

4.26e-05149584768877bade04ca0321593b8470b5011ad8270431
ToppCellControl-Myeloid-Neutrophils|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PIK3AP1 PTPRC CSF1R PTPRE

4.73e-05153584c33d63b2d1a220bc428e776b157b23faa43ea8ca
ToppCellControl-Myeloid-Neutrophils-Neutrophils|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PIK3AP1 PTPRC CSF1R PTPRE

4.73e-05153584e3630f2b10f33092a3b6a63dba3a39fbdecbc7bd
ToppCelldroplet-Marrow-BM-30m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF CSF1R UBR4 CTNND1

5.91e-0516258475df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCellfacs-Heart-RA-18m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 PTPRC CSF1R KRT20

6.05e-05163584da7ab9582e8070b07ca628a6394c86684d37d6ef
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIK3AP1 PTPRC CSF1R PTPRE

6.19e-051645846a113191ea91d103d21c5f056b1950217688ea26
ToppCellNS-control-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PIK3AP1 PTPRE CCDC168 PHACTR1

6.34e-051655848b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCellcontrol-Myeloid-pDC|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PIK3AP1 PTPRE CCDC168 PHACTR1

6.34e-05165584243c74adf8d993ff92acbff2768bdc5a1693eca3
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

SPAG1 DCDC1 CCDC181 NEK11

6.64e-0516758426cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellfacs-Kidney-nan-3m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 PTPRC CSF1R PTPRE

6.64e-05167584991a93e1075d562b7391f0689b2f62c1351d48d1
ToppCellfacs-Kidney-nan-3m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 PTPRC CSF1R PTPRE

6.64e-05167584f22d1471c785b30d096ec5cdc68974e850ed7de0
ToppCellfacs-Kidney-nan-3m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 PTPRC CSF1R PTPRE

6.64e-05167584934905aeaafbc215ec8f6a7903498b0e258b9220
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 PTPRC CNTRL MYH15

7.12e-05170584a965e3ee6818790a4a6916824fde64333d9b11b7
ToppCellfacs-Heart-LV-18m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 PTPRC CSF1R STXBP2

7.12e-051705844eaa22040e475100061475123aefa32b56481464
ToppCellfacs-Heart-LV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 PTPRC CSF1R STXBP2

7.12e-0517058460041b2e57e958f300a5bc76851705c8baf297c2
ToppCellfacs-Heart-LV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 PTPRC CSF1R STXBP2

7.12e-05170584793dde64f5517538b66de5f461a445c4ad6dd7b3
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC CSF1R ATRX KTN1

7.62e-05173584869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC CSF1R ATRX KTN1

7.62e-051735840672bd8a4a9d18af343d01f09253fb3388896c10
ToppCellfacs-Brain_Myeloid-Cerebellum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC CSF1R ATRX KTN1

7.62e-05173584870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 PTPRC CSF1R STXBP2

7.96e-05175584e991ffa4d1d278a011592b9915cd35fe76db20cc
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PIK3AP1 PTPRC CSF1R PTPRE

8.14e-0517658498176bf3c961d5262593e2d5d002836adb010e13
ToppCellLPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PIK3AP1 PTPRC CSF1R PTPRE

8.32e-05177584cdad5a2f672a7f07c05669bfcaf1ec74defd3de7
ToppCellLPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PIK3AP1 PTPRC CSF1R PTPRE

8.32e-05177584991ae76bb615392d84aeb89886148fa42c1c649c
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPRC CSF1R PTPRE PHACTR1

8.51e-051785848184a2b9872f7ca12a9823535de485e841aeffb1
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3AP1 PTPRC CSF1R PTPRE

8.51e-05178584aa9f68a66e292f331faef881bbd0d028f0f2b0c5
ToppCellLPS-IL1RA-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PIK3AP1 PTPRC CSF1R PTPRE

8.88e-0518058497241f62ee133dcb0d4855ffda5dd1349de9f7b2
ToppCellLPS-IL1RA-Myeloid-Monocytes,_Macrophages|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PIK3AP1 PTPRC CSF1R PTPRE

8.88e-0518058441896546cd1cc458e08c0d4e19aa4860e5d4fcd6
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIK3AP1 PTPRC CSF1R STXBP2

9.07e-05181584bad77767e64cc093a827a6b0f3f401f3f108e457
ToppCellControl-Myeloid|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PIK3AP1 PTPRC CSF1R PTPRE

9.07e-0518158425170e5285996cc80337d5f86a0255569861ae77
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PIK3AP1 PTPRC CSF1R PTPRE

9.27e-05182584d5d6bc16458bc665e7ad6669040d79f73f640044
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC ATRX KTN1 CNTRL

9.27e-05182584f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PIK3AP1 PTPRC CSF1R PTPRE

9.27e-051825840b59ead4bb4486c7ec2ee90b94ee3a09905612c5
ToppCell5'-Adult-LymphNode-Hematopoietic-Myeloid-Monocytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIK3AP1 CSF1R STXBP2 PTPRE

9.27e-051825841fb9bdf2e9f0a9c230f109b471672f9c31e27c82
ToppCellLPS_only-Myeloid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PIK3AP1 PTPRC CSF1R CENPE

9.27e-05182584666ac86ee5f6fa9241ae8d80340743707e54b278
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PIK3AP1 PTPRC CSF1R PTPRE

9.47e-0518358424679153b654c148dbd572e9013c0a6e58718ada
ToppCell367C-Fibroblasts-Fibroblast-D-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CSF1R STXBP2 PTPRE PHACTR1

9.47e-05183584b12b89debc9dd6396188bc8fe44f54c01c560966
ToppCell367C-Fibroblasts-Fibroblast-D|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CSF1R STXBP2 PTPRE PHACTR1

9.47e-0518358419cc0009f5332b6e4d4274df123eebbfc80b669a
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTPRC CSF1R STXBP2 PTPRE

9.67e-05184584d7f348aa8901d819c68da20728b9238407bcdca9
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIK3AP1 CSF1R PTPRE PHACTR1

9.67e-05184584b45b1fdba13c8ed2a04a4fb3b62d8ad92785c768
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

EFR3B PEAK1 DMD PHACTR1

9.87e-0518558432b4e68e551d435a732f253f6ad83408c759a642
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC ATRX KTN1 CNTRL

9.87e-051855847adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellwk_08-11-Hematologic-Myeloid-Cycling_DC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PTPRC CSF1R STXBP2 PHACTR1

1.01e-04186584de1f0bc5dbf6dc0e716f5ebbf2bbcfe249811c54
ToppCellLPS-antiTNF-Myeloid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PIK3AP1 PTPRC CSF1R PTPRE

1.01e-04186584839c6da5244f469461b2e5563e36162b2911cd01
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CSF1R STXBP2 PTPRE PHACTR1

1.01e-041865840859737021747518731aa67fe181d4ca4fdc0721
ToppCellwk_08-11-Hematologic-Myeloid-S100A12-lo_cla._mono.|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PTPRC CSF1R STXBP2 PHACTR1

1.01e-04186584be50f5c7f32b3126442ebff1e7d38aa78b6e4e71
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

PARP4 ATRX FAM83B IWS1

1.01e-0418658403db813598b67b1e08f759758a1c2023396921fa
ToppCellILEUM-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PTPRC RNF207 GOLGB1 PHACTR1

1.03e-041875840099def970fbc828756fbf853eca2ce77b8cd342
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRC CSF1R CENPE CNTRL

1.03e-0418758473931a5ea73799095daff100b5f18853c57c74dc
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PIK3AP1 PTPRC CSF1R PTPRE

1.05e-041885843be2d50148daa4eddddc2c7f269f45c97f7e4931
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

PTPRC AHCTF1 ZNF407 GOLGB1

1.05e-04188584ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellMonocytes-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

PTPRC CSF1R STXBP2 PTPRE

1.05e-04188584756375cf9c9cccc4fb4a7f5e4756fa3fc36a7892
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 PTPRC CSF1R PTPRE

1.05e-041885844e27ada1bda88811b73376c8a6136cbfc83bfdb9
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIK3AP1 PTPRC CSF1R STXBP2

1.05e-04188584239bec13476dd43bebc2c6eba8d1fe35f2744673
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PIK3AP1 PTPRC CSF1R PTPRE

1.07e-04189584440c422369de1c49112d18cf8c506a2a3a81f6ba
ToppCellMacrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

PIK3AP1 PTPRC CSF1R STXBP2

1.07e-04189584c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_macrophage|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PIK3AP1 PTPRC CSF1R PTPRE

1.07e-04189584a438c64a893d43f781ede42e1c7b615b74dc76ef
ToppCellMonocytes-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

PTPRC CSF1R STXBP2 PTPRE

1.07e-0418958422d08c7dde697f385100f72e009eeac8d19d329d
Diseasemigraine without aura, susceptibility to, 4, systolic blood pressure

STXBP2 PHACTR1

2.12e-054562EFO_0006335, MONDO_0011847
Diseasemigraine without aura

STXBP2 PHACTR1

3.52e-055562MONDO_0100431
Diseasepulse pressure measurement, migraine without aura, susceptibility to, 4

STXBP2 PHACTR1

1.26e-049562EFO_0005763, MONDO_0011847
Diseasemagnesium measurement

DCDC1 CCDC168 IZUMO3

2.72e-0466563EFO_0004845
Diseaseintellectual disability (implicated_via_orthology)

ATRX UBR4 RYK

3.97e-0475563DOID:1059 (implicated_via_orthology)
Diseaselung small cell carcinoma (is_marker_for)

CSF1R ATRX

4.17e-0416562DOID:5409 (is_marker_for)
Diseasemigraine without aura, susceptibility to, 4

STXBP2 PHACTR1

4.17e-0416562MONDO_0011847
Diseasecervical artery dissection

STXBP2 PHACTR1

4.72e-0417562EFO_1000059
Diseasemigraine disorder, systolic blood pressure

STXBP2 PHACTR1

5.31e-0418562EFO_0006335, MONDO_0005277
DiseaseMalignant neoplasm of breast

VWF PTPRC CSF1R ZNF277 KTN1 UBR4 DMD GOLGB1

9.04e-041074568C0006142
Diseasemigraine disorder, pulse pressure measurement

STXBP2 PHACTR1

1.12e-0326562EFO_0005763, MONDO_0005277
Diseaseretinal degeneration (biomarker_via_orthology)

PTPRC DMD

1.30e-0328562DOID:8466 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
LMTELEIEKSLKHHE

CNTRL

1401

Q7Z7A1
TMTDKEDHVIISDSH

ALS2

241

Q96Q42
SITHALKHVSDDMKT

CAP1

266

Q01518
HDLETAMHVKEKEAL

CLIP2

671

Q9UDT6
DLTSHEISLEEMKKH

DMD

1416

P11532
LKSHIKEELMHGEEA

PIK3AP1

401

Q6ZUJ8
EDEMASHLDSKFHKE

AKAP8L

401

Q9ULX6
KHTTEHEMSILKKSL

CCNB3

336

Q8WWL7
HEAEKEDSADKVMSH

RABEPK

321

Q7Z6M1
HSSDSEEEEHKKQKM

IWS1

361

Q96ST2
EKVILSMTAKEHHKE

DCDC1

421

M0R2J8
ELDVSSLEKHLQTMH

PTPRE

401

P23469
ALHKDIHMATKEVVD

KIAA1109

3301

Q2LD37
GTLFHLTKHKTDEME

CCDC178

506

Q5BJE1
EDLLKSSKSMHNVTH

FAM83B

701

Q5T0W9
KKHAHLTDTEIMTLV

PFDN1

41

O60925
IVVESKHDSHMAKER

PDZK1P1

371

A8MUH7
PKKILSHMTHEVTED

PEAK1

1041

Q9H792
HSSHDDLEIKTKIRM

EFR3B

151

Q9Y2G0
DHLMTKVEELQKHSA

FKBP15

531

Q5T1M5
LSVDVLHEKTHLKGM

NEK11

386

Q8NG66
KVLEHKLKEADEMHT

KTN1

1116

Q86UP2
LHENETSHEMKKQTL

PARP4

1141

Q9UKK3
QSHLSMKESLEHTLE

KRT20

301

P35900
EFKSSEMEVHEESKH

PHACTR4

681

Q8IZ21
KSTEMEVHELSRHLT

PHACTR1

561

Q9C0D0
KLESHTSEKELIMIA

HERC5

351

Q9UII4
DLKENETVMEHTKRH

CCDC181

51

Q5TID7
TSHHMLTAQEEKELL

CDC16

171

Q13042
EAKLSRKQVDSEHMH

ATRX

461

P46100
TAHADEKEALMSELK

CSF1R

621

P07333
VHTDMTKDLKEEHLK

CBR4

181

Q8N4T8
HQELLKQMKETESHS

CEP57L1

341

Q8IYX8
LHSVSEERTDEMTHK

AHCTF1

2061

Q8WYP5
HKDKAKTADVESTMH

CCDC168

2786

Q8NDH2
HLHSMKRIELDDSIS

RYK

251

P34925
LENSLHEAKESAMHK

CENPE

2386

Q02224
HEAKESAMHKESKII

CENPE

2391

Q02224
KMEIVDHALHALTDE

CTNND1

486

O60716
KEMIHLSFKVSHSDK

IZUMO3

56

Q5VZ72
DLTKHHSLIKAEIMG

RNF207

451

Q6ZRF8
QHEEEEMTLSHSALK

RPGRIP1

1056

Q96KN7
MEDHDIDVKTKGSHI

PUS7L

656

Q9H0K6
DLHMEEEKLSSLSKA

MYH15

1021

Q9Y2K3
GDELMTLAHKHIVKT

STRAP

91

Q9Y3F4
ELTIMKTLEAHKDSH

CLASP1

1386

Q7Z460
EVKHSALSVELHSDM

VWF

2006

P04275
IKKEEDKMHFHETET

SPAG1

106

Q07617
LRHMHIADVSKKVTE

STXBP2

291

Q15833
DSKETVKLSHEDDHI

PHF3

321

Q92576
RKKHVDSMAELTEHV

MYH16

356

Q9H6N6
TSKENLLDHMKEHEG

ZNF507

921

Q8TCN5
TSKMRHLETHDTDKE

ZBTB17

431

Q13105
KIEEHSEDMETHVKT

ZUP1

161

Q96AP4
SEDMETHVKTKHANL

ZUP1

166

Q96AP4
DLRTHMEETKHTSLL

ZNF277

371

Q9NRM2
EFETSSELKEHMKTH

ZNF236

161

Q9UL36
TQMKTHDAESVLKHL

ZNF407

466

Q9C0G0
HHMATLASIIKEVDK

UBR4

681

Q5T4S7
PLKHELEMSKESEHD

PTPRC

986

P08575
AIHMTKDATKEALHA

UHRF1BP1

1021

Q6BDS2
LEQKHKAEMEEKTSH

GOLGB1

366

Q14789