Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransition metal ion binding

PEPD TRIM49D1 KDM7A THRB ATP7B POLR1A COMMD1 CYP2J2 MYCBP2 F5

5.50e-0511893810GO:0046914
GeneOntologyMolecularFunctioncopper ion binding

ATP7B COMMD1 F5

4.38e-0478383GO:0005507
GeneOntologyMolecularFunctionrRNA binding

RPS4Y2 RPS4X RPS4Y1

4.55e-0479383GO:0019843
GeneOntologyCellularComponentsmall-subunit processome

RPS4Y2 RPS4X RPS4Y1 PWP2

1.08e-0576384GO:0032040
GeneOntologyCellularComponentpreribosome

RPS4Y2 RPS4X RPS4Y1 PWP2

5.37e-05114384GO:0030684
GeneOntologyCellularComponentcytosolic small ribosomal subunit

RPS4Y2 RPS4X RPS4Y1

7.97e-0546383GO:0022627
GeneOntologyCellularComponentsmall ribosomal subunit

RPS4Y2 RPS4X RPS4Y1

4.29e-0481383GO:0015935
GeneOntologyCellularComponentcytoplasmic ribonucleoprotein granule

RPS4Y2 RPS4X RPS4Y1 SYNE1

1.40e-03269384GO:0036464
GeneOntologyCellularComponentcytosolic ribosome

RPS4Y2 RPS4X RPS4Y1

1.48e-03124383GO:0022626
GeneOntologyCellularComponentribonucleoprotein granule

RPS4Y2 RPS4X RPS4Y1 SYNE1

1.78e-03287384GO:0035770
DomainRIBOSOMAL_S4E

RPS4Y2 RPS4X RPS4Y1

7.16e-093373PS00528
Domain40S_S4_C

RPS4Y2 RPS4X RPS4Y1

7.16e-093373IPR032277
DomainRibosomal_S4e_N_CS

RPS4Y2 RPS4X RPS4Y1

7.16e-093373IPR018199
DomainRibosomal_S4e

RPS4Y2 RPS4X RPS4Y1

7.16e-093373PF00900
DomainRS4NT

RPS4Y2 RPS4X RPS4Y1

7.16e-093373PF08071
DomainRibosomal_S4e_central_region

RPS4Y2 RPS4X RPS4Y1

7.16e-093373IPR013845
DomainRibosomal_S4e_N

RPS4Y2 RPS4X RPS4Y1

7.16e-093373IPR013843
DomainRibosomal_S4e_central

RPS4Y2 RPS4X RPS4Y1

7.16e-093373PD002667
Domain40S_S4_C

RPS4Y2 RPS4X RPS4Y1

7.16e-093373PF16121
DomainRibosomal_S4e

RPS4Y2 RPS4X RPS4Y1

7.16e-093373IPR000876
DomainS4

RPS4Y2 RPS4X RPS4Y1

7.14e-085373PS50889
DomainS4

RPS4Y2 RPS4X RPS4Y1

7.14e-085373SM00363
DomainS4_RNA-bd

RPS4Y2 RPS4X RPS4Y1

1.43e-076373IPR002942
DomainKOW

RPS4Y2 RPS4X RPS4Y1

1.17e-0611373IPR005824
DomainKOW

RPS4Y2 RPS4X RPS4Y1

1.17e-0611373PF00467
DomainS4

RPS4X RPS4Y1

2.29e-054372PF01479
DomainActinin_actin-bd_CS

MACF1 SYNE1

9.41e-0423372IPR001589
DomainACTININ_2

MACF1 SYNE1

9.41e-0423372PS00020
DomainACTININ_1

MACF1 SYNE1

9.41e-0423372PS00019
DomainSpectrin

MACF1 SYNE1

9.41e-0423372PF00435
DomainSpectrin_repeat

MACF1 SYNE1

1.50e-0329372IPR002017
DomainSpectrin/alpha-actinin

MACF1 SYNE1

1.82e-0332372IPR018159
DomainSPEC

MACF1 SYNE1

1.82e-0332372SM00150
DomainQuinoprotein_ADH-like_supfam

EML5 PWP2

4.94e-0353372IPR011047
DomainCH

MACF1 SYNE1

7.34e-0365372SM00033
PathwayREACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY

RPS4Y2 RPS4X RPS4Y1

4.15e-0537263M46427
PathwayREACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY

RPS4Y2 RPS4X RPS4Y1

1.09e-0451263M45019
PathwayREACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

RPS4Y2 RPS4X RPS4Y1

1.78e-0460263M721
PathwayREACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

RPS4Y2 RPS4X RPS4Y1

2.26e-0465263MM15416
PathwayBIOCARTA_EXTRINSIC_PATHWAY

FGB F5

2.52e-0413262M4470
PathwayBIOCARTA_EXTRINSIC_PATHWAY

FGB F5

2.52e-0413262MM1395
PathwayREACTOME_MAJOR_PATHWAY_OF_RRNA_PROCESSING_IN_THE_NUCLEOLUS_AND_CYTOSOL

RPS4Y2 RPS4X RPS4Y1 PWP2

3.09e-04180264MM15324
PathwayKEGG_MEDICUS_REFERENCE_TRANSLATION_INITIATION

RPS4Y2 RPS4X RPS4Y1

4.32e-0481263M47786
PathwayWP_CYTOPLASMIC_RIBOSOMAL_PROTEINS

RPS4Y2 RPS4X RPS4Y1

4.32e-0481263MM15911
PathwayREACTOME_RRNA_PROCESSING

RPS4Y2 RPS4X RPS4Y1 PWP2

5.05e-04205264M27685
PathwayREACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

RPS4Y2 RPS4X RPS4Y1

6.68e-0494263M29556
PathwayREACTOME_NONSENSE_MEDIATED_DECAY_NMD_INDEPENDENT_OF_THE_EXON_JUNCTION_COMPLEX_EJC

RPS4Y2 RPS4X RPS4Y1

7.10e-0496263MM15705
PathwayWP_BLOOD_CLOTTING_CASCADE

FGB F5

7.39e-0422262M39480
PathwayREACTOME_COMMON_PATHWAY_OF_FIBRIN_CLOT_FORMATION

FGB F5

7.39e-0422262M17879
PathwayREACTOME_COMMON_PATHWAY_OF_FIBRIN_CLOT_FORMATION

FGB F5

7.39e-0422262MM14558
PathwayREACTOME_SARS_COV_1_HOST_INTERACTIONS

RPS4Y2 RPS4X RPS4Y1

7.54e-0498263M46424
PathwayBIOCARTA_INTRINSIC_PATHWAY

FGB F5

8.08e-0423262M15997
PathwayBIOCARTA_INTRINSIC_PATHWAY

FGB F5

8.08e-0423262MM1427
PathwayWP_BLOOD_CLOTTING_CASCADE

FGB F5

8.08e-0423262MM15936
PathwayREACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

RPS4Y2 RPS4X RPS4Y1

8.47e-04102263M29813
PathwayREACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

RPS4Y2 RPS4X RPS4Y1

1.14e-03113263M567
PathwayREACTOME_NONSENSE_MEDIATED_DECAY_NMD

RPS4Y2 RPS4X RPS4Y1

1.20e-03115263MM15640
PathwayREACTOME_NONSENSE_MEDIATED_DECAY_NMD

RPS4Y2 RPS4X RPS4Y1

1.23e-03116263M27921
PathwayREACTOME_SELENOAMINO_ACID_METABOLISM

RPS4Y2 RPS4X RPS4Y1

1.29e-03118263M27170
PathwayREACTOME_EUKARYOTIC_TRANSLATION_INITIATION

RPS4Y2 RPS4X RPS4Y1

1.36e-03120263M27686
PathwayREACTOME_EUKARYOTIC_TRANSLATION_INITIATION

RPS4Y2 RPS4X RPS4Y1

1.46e-03123263MM15415
PathwayREACTOME_SARS_COV_1_INFECTION

RPS4Y2 RPS4X RPS4Y1

2.24e-03143263M39006
PathwayREACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE

FGB F5

2.32e-0339262M2844
PathwayREACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE

FGB F5

2.32e-0339262MM14559
PathwayREACTOME_INFLUENZA_INFECTION

RPS4Y2 RPS4X RPS4Y1

2.92e-03157263M4669
PathwayREACTOME_CELLULAR_RESPONSE_TO_STARVATION

RPS4Y2 RPS4X RPS4Y1

2.92e-03157263M41835
PathwayREACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

RPS4Y2 RPS4X RPS4Y1

3.78e-03172263M27876
PathwayWP_COPPER_HOMEOSTASIS

ATP7B COMMD1

4.25e-0353262M39349
PathwayWP_COMPLEMENT_AND_COAGULATION_CASCADES

FGB F5

5.07e-0358262M39649
PathwayWP_DENGUE2_INTERACTIONS_WITH_COMPLEMENT_AND_COAGULATION_CASCADES

FGB F5

5.25e-0359262M48343
PathwayREACTOME_SARS_COV_2_HOST_INTERACTIONS

RPS4Y2 RPS4X RPS4Y1

6.08e-03204263M45011
PathwayREACTOME_SIGNALING_BY_BRAF_AND_RAF1_FUSIONS

FGB KDM7A

6.34e-0365262M38994
Pubmed

Relationship between the monosomy X phenotype and Y-linked ribosomal protein S4 (Rps4) in several species of mammals: a molecular evolutionary analysis of Rps4 homologs.

RPS4Y2 RPS4X RPS4Y1

1.30e-0933938808278
Pubmed

Inactivation of the Rps4 gene on the mouse X chromosome.

RPS4Y2 RPS4X RPS4Y1

1.30e-0933931783379
Pubmed

Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome.

RPS4Y2 RPS4X RPS4Y1

1.30e-0933932124517
Pubmed

Expression level of Rps4 mRNA in 39,X mice and 40,XX mice.

RPS4Y2 RPS4X RPS4Y1

1.30e-0933938187552
Pubmed

Structure and function of ribosomal protein S4 genes on the human and mouse sex chromosomes.

RPS4Y2 RPS4X RPS4Y1

5.21e-0943938139551
Pubmed

Maintenance of X inactivation of the Rps4, Zfx, and Ube1 genes in a mouse in vitro system.

RPS4Y2 RPS4X RPS4Y1

1.30e-0853937681608
Pubmed

Use of a reverse transcriptase-polymerase chain reaction assay to analyze allele-specific expression in individual hippocampal neurons.

RPS4Y2 RPS4X RPS4Y1

1.30e-0853939562962
Pubmed

An evaluation of the inactive mouse X chromosome in somatic cell hybrids.

RPS4Y2 RPS4X RPS4Y1

4.55e-0873938460399
Pubmed

Embryonic growth and the evolution of the mammalian Y chromosome. II. Suppression of selfish Y-linked growth factors may explain escape from X-inactivation and rapid evolution of Sry.

RPS4Y2 RPS4X RPS4Y1

4.55e-0873937928394
Pubmed

Physical mapping of 2000 kb of the mouse X chromosome in the vicinity of the Xist locus.

RPS4Y2 RPS4X RPS4Y1

7.27e-0883938468051
Pubmed

Cloning and localization of the murine Xpct gene: evidence for complex rearrangements during the evolution of the region around the Xist gene.

RPS4Y2 RPS4X RPS4Y1

1.09e-0793939545634
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SMARCA1 FGB RNF213 MACF1 ZNF536 GPATCH4 ATP7B EML5 ATAD5 BRD9

3.03e-071116391031753913
Pubmed

Rps4 maps near the inactivation center on the mouse X chromosome.

RPS4Y2 RPS4X RPS4Y1

3.70e-07133931740345
Pubmed

XIST and the mapping of the X chromosome inactivation centre.

RPS4Y2 RPS4X RPS4Y1

3.70e-07133931772416
Pubmed

Developmental expression of Commd1 in the liver of the Jackson toxic milk mouse.

ATP7B COMMD1

1.23e-06239217910951
Pubmed

Roles of COMM-domain-containing 1 in stability and recruitment of the copper-transporting ATPase in a mouse hepatoma cell line.

ATP7B COMMD1

1.23e-06239220433422
Pubmed

Functional equivalence of human X- and Y-encoded isoforms of ribosomal protein S4 consistent with a role in Turner syndrome.

RPS4X RPS4Y1

1.23e-0623928358435
Pubmed

Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome.

RPS4Y2 RPS4X RPS4Y1

1.47e-062039316635246
Pubmed

Associations of the beta-fibrinogen Hae III and factor XIII Val34Leu gene variants with venous thrombosis.

FGB F5

3.67e-06339217582472
Pubmed

Copper-induced translocation of the Wilson disease protein ATP7B independent of Murr1/COMMD1 and Rab7.

ATP7B COMMD1

3.67e-06339218974300
Pubmed

Distinct Wilson's disease mutations in ATP7B are associated with enhanced binding to COMMD1 and reduced stability of ATP7B.

ATP7B COMMD1

3.67e-06339217919502
Pubmed

Genetic variations observed in arterial and venous thromboembolism--relevance for therapy, risk prevention and prognosis.

FGB F5

3.67e-06339212747593
Pubmed

Molecular analysis of Wilson patients: direct sequencing and MLPA analysis in the ATP7B gene and Atox1 and COMMD1 gene analysis.

ATP7B COMMD1

3.67e-06339222677543
Pubmed

Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction.

RPS4Y2 RPS4Y1

3.67e-06339222708584
Pubmed

Advanced age, low left atrial appendage velocity, and factor V promoter sequence variation as predictors of left atrial thrombosis in patients with nonvalvular atrial fibrillation.

FGB F5

3.67e-06339220082208
Pubmed

Influence of Amerindian mitochondrial DNA haplogroups on thrombosis susceptibility and frequency of four genetic prothrombotic variants in Southern Chilean subjects.

FGB F5

7.34e-06439220064497
Pubmed

Clusterin and COMMD1 independently regulate degradation of the mammalian copper ATPases ATP7A and ATP7B.

ATP7B COMMD1

7.34e-06439222130675
Pubmed

Combined effect of hemostatic gene polymorphisms and the risk of myocardial infarction in patients with advanced coronary atherosclerosis.

FGB F5

7.34e-06439218253477
Pubmed

-455G/A beta-fibrinogen gene polymorphism, factor V Leiden, prothrombin G20210A mutation and MTHFR C677T, and placental vascular complications.

FGB F5

7.34e-06439215091001
Pubmed

The effect of four hemostatic gene polymorphisms on the outcome of septic critically ill patients.

FGB F5

7.34e-06439220051843
Pubmed

Analysis of genes from inner ear developmental-stage cDNA subtraction reveals molecular regionalization of the otic capsule.

RPS4Y2 RPS4X RPS4Y1

8.32e-063539315031101
Pubmed

Absence of association between polymorphisms in the hemostatic factor pathway genes and carotid intimal medial thickness: the Framingham Heart Study.

FGB F5

1.22e-05539214963283
Pubmed

Thrombophilic gene polymorphisms and recurrent pregnancy loss in Greek women.

FGB F5

1.22e-05539228603947
Pubmed

[Genetics of blood coagulation in young stroke patients].

FGB F5

1.22e-05539212122980
Pubmed

[Associations of hemostasis factors genes with early development of ischemic heart disease and manifestation of myocardial infarction in young age].

FGB F5

1.22e-05539216353042
Pubmed

Polymorphisms in coagulation factors and the risk of recurrent cardiovascular events in men after a first myocardial infarction.

FGB F5

1.22e-05539218284606
Pubmed

The copper toxicosis gene product Murr1 directly interacts with the Wilson disease protein.

ATP7B COMMD1

1.22e-05539212968035
Pubmed

Mutations and polymorphisms in genes affecting haemostasis components in children with thromboembolic events.

FGB F5

1.83e-05639217230042
Pubmed

Connection between genetically determined blood coagulation factors and haemorheology.

FGB F5

1.83e-05639218503143
Pubmed

Spectrum and prevalence of prothrombotic single nucleotide polymorphism profiles in the Greek Cypriot population.

FGB F5

1.83e-05639212518110
Pubmed

Prothrombotic phenotype of protein Z deficiency.

FGB F5

1.83e-05639210829076
Pubmed

Which thrombophilic gene mutations are risk factors for recurrent pregnancy loss?

FGB F5

1.83e-05639216938111
Pubmed

[Pharmacogenetics of the local thrombolysis in patients with deep vein thrombosis].

FGB F5

1.83e-05639216466010
Pubmed

Haemostatic genetic variants, ABO blood group and bleeding risk during oral anticoagulant treatment after cerebral ischaemia of arterial origin.

FGB F5

1.83e-05639217994314
Pubmed

Characterization of COMMD protein-protein interactions in NF-kappaB signalling.

ATP7B COMMD1

1.83e-05639216573520
Pubmed

Role of thrombophilic gene polymorphisms in branch retinal vein occlusion.

FGB F5

1.83e-05639216157382
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SMARCA1 RPS4Y2 PKHD1 MACF1 ZBED4 RPS4X RPS4Y1 SYNE1 PWP2

2.43e-05144239935575683
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

MACF1 EML5 CYP2J2 SYNE1

2.56e-0515239434299191
Pubmed

Fibrinogen Aalpha Thr312Ala polymorphism is associated with chronic thromboembolic pulmonary hypertension.

FGB F5

2.56e-05739218057060
Pubmed

Early pregnancy loss in celiac women: The role of genetic markers of thrombophilia.

FGB F5

2.56e-05739219395327
Pubmed

Mutations and polymorphisms in genes affecting hemostasis proteins and homocysteine metabolism in children with arterial ischemic stroke.

FGB F5

2.56e-05739216567932
Pubmed

Polymorphisms in prothrombotic genes and their impact on ischemic stroke in a Sardinian population.

FGB F5

2.56e-05739215968394
Pubmed

Multiple thrombophilic gene mutations rather than specific gene mutations are risk factors for recurrent miscarriage.

FGB F5

2.56e-05739216635210
Pubmed

A role of TNF-alpha gene variant on juvenile ischemic stroke: a case-control study.

FGB F5

2.56e-05739216324093
Pubmed

Thrombophilic gene polymorphisms are risk factors for unexplained infertility.

FGB F5

2.56e-05739218930220
Pubmed

Replication of findings on the association of genetic variation in 24 hemostasis genes and risk of incident venous thrombosis.

FGB F5

2.56e-05739219682239
Pubmed

The nuclear transcription factor RARalpha associates with neuronal RNA granules and suppresses translation.

RPS4Y2 RPS4X RPS4Y1

3.11e-055439318495661
Pubmed

Impact of genetic polymorphisms on platelet function and aspirin resistance.

FGB F5

4.39e-05939219923980
Pubmed

Multi-locus candidate gene polymorphisms and risk of myocardial infarction: a population-based, prospective genetic analysis.

FGB F5

4.39e-05939216420563
Pubmed

Candidate genetic markers and the risk of restenosis after coronary angioplasty.

FGB F5

4.39e-05939212899665
Pubmed

No evidence of association between prothrombotic gene polymorphisms and the development of acute myocardial infarction at a young age.

FGB F5

4.39e-05939212615788
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

SMARCA1 RNF213 MACF1 GPATCH4 POLR1A RPS4X

5.22e-0560139633658012
Pubmed

Genetic polymorphisms associated with thrombophilia and vascular disease in women with unexplained late intrauterine fetal death: a multicenter study.

FGB F5

5.48e-051039214706682
Pubmed

Prevalence of prothrombotic polymorphisms in Greece.

FGB F5

5.48e-051039219072566
Pubmed

Hemostatic gene polymorphisms in young Sardinian with non-fatal acute myocardial infarction.

FGB F5

5.48e-051039220036902
Pubmed

A prospective case-control study analyzes 12 thrombophilic gene mutations in Turkish couples with recurrent pregnancy loss.

FGB F5

5.48e-051039219906129
Pubmed

A comprehensive analysis of 12 thrombophilic mutations and related parameters in patients with inflammatory bowel disease: data from Turkey.

FGB F5

5.48e-051039217111197
Pubmed

Vascular at-risk genotypes and disease severity in Lebanese sickle cell disease patients.

FGB F5

5.48e-051039220425806
Pubmed

Clinical factors such as B-type natriuretic peptide link to factor VII, endothelial NO synthase and estrogen receptor alpha polymorphism in elderly women.

FGB F5

5.48e-051039219560472
Pubmed

Activating signal cointegrator 1, a novel transcription coactivator of nuclear receptors, and its cytosolic localization under conditions of serum deprivation.

GTF2A1 THRB

6.70e-051139210454579
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

MACF1 GTF2A1 F5 SYNE1

7.03e-0519739420811636
Pubmed

Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes.

RPS4Y2 RPS4X RPS4Y1

8.00e-057439329795351
Pubmed

Potential thrombophilic mutations/polymorphisms in patients with no flow-limiting stenosis after myocardial infarction.

FGB F5

8.03e-051239212514663
Pubmed

Gene variants associated with venous thrombosis: confirmation in the MEGA study.

FGB F5

8.03e-051239220128871
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

RNF213 MACF1 MYCBP2

8.66e-057639327542412
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MACF1 ZNF536 SETD1B ZBED4 SYNE1

8.89e-0540739512693553
Pubmed

Genetic cardiovascular risk factors and age-related macular degeneration.

FGB F5

9.48e-051339219860767
Pubmed

Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches.

RPS4X RPS4Y1

9.48e-051339214660691
Pubmed

Prothrombotic genetic variants and atherosclerosis in patients with cerebral ischemia of arterial origin.

FGB F5

9.48e-051339218848323
Pubmed

Genetic influences on blood pressure within the Stanislas Cohort.

FGB F5

9.48e-051339215076187
Pubmed

Gene polymorphisms implicated in influencing susceptibility to venous and arterial thromboembolism: frequency distribution in a healthy German population.

FGB F5

9.48e-051339217003923
Pubmed

Structure of the human 80S ribosome.

RPS4Y2 RPS4X RPS4Y1

1.09e-048239325901680
Pubmed

Gene polymorphisms in association with emerging cardiovascular risk markers in adult women.

FGB F5

1.11e-041439220078877
Pubmed

Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling.

RPS4Y2 RPS4X RPS4Y1

1.13e-048339319799774
Pubmed

A male germ-cell-specific ribosome controls male fertility.

RPS4Y2 RPS4X RPS4Y1

1.21e-048539336517592
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

MACF1 POLR1A MYCBP2 F5 RPS4X SYNE1 PWP2

1.27e-04102439724711643
Pubmed

A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo.

GTF2A1 THRB

1.27e-041539210567404
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

MACF1 GPATCH4 POLR1A MYCBP2 ATAD5 BRD9

1.45e-0472439636232890
Pubmed

Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning.

RPS4Y2 RPS4X RPS4Y1

1.73e-049639321529712
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

SMARCA1 RNF213 EEF2K POLR1A

1.76e-0425039433536335
Pubmed

Isolation of genes identified in mouse renal proximal tubule by comparing different gene expression profiles.

RPS4Y2 RPS4X RPS4Y1

1.84e-04983939507200
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

MACF1 GPATCH4 POLR1A MYCBP2 ATAD5 PWP2

1.87e-0475939635915203
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

MACF1 SYNE1 KIAA0753

2.01e-041013939872452
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

MACF1 GTF2A1 EEF2K MYCBP2 ATAD5 SYNE1 KIAA0753 PWP2

2.06e-04148739833957083
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

MACF1 GPATCH4 POLR1A ATAD5 SYNE1 ZNF652 BRD9 PWP2

2.16e-04149739831527615
Pubmed

Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.

RNF213 MYCBP2 RPS4X RPS4Y1

2.17e-0426439432814769
Pubmed

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.

RPS4Y2 RPS4X RPS4Y1

2.20e-0410439326167872
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

MACF1 SYNE1

2.30e-042039221689717
Pubmed

Candidate genes and cerebral palsy: a population-based study.

FGB F5

2.54e-042139218977990
Pubmed

Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.

ZNF536 PALMD BRD9

2.59e-0411039337219487
GeneFamilyS ribosomal proteins

RPS4Y2 RPS4X RPS4Y1

1.93e-0534283728
CoexpressionTABULA_MURIS_SENIS_PANCREAS_PANCREATIC_STELLATE_CELL_AGEING

RPS4Y2 RPS4X RPS4Y1

2.35e-079383MM3821
CoexpressionBILANGES_SERUM_RESPONSE_TRANSLATION

RPS4Y2 RPS4X RPS4Y1

1.94e-0536383MM1308
CoexpressionTABULA_MURIS_SENIS_KIDNEY_FIBROBLAST_AGEING

RPS4Y2 RPS4X RPS4Y1

2.48e-0539383MM3721
CoexpressionTABULA_MURIS_SENIS_LIVER_ENDOTHELIAL_CELL_OF_HEPATIC_SINUSOID_AGEING

RPS4Y2 MACF1 MYCBP2 RPS4X RPS4Y1 BRD9

2.84e-05418386MM3752
CoexpressionTABULA_MURIS_SENIS_LUNG_NON_CLASSICAL_MONOCYTE_AGEING

RPS4Y2 RPS4X RPS4Y1

4.95e-0549383MM3772
CoexpressionGSE7568_IL4_VS_IL4_AND_DEXAMETHASONE_TREATED_MACROPHAGE_DN

PKHD1 KDM7A EML5 MYCBP2

6.71e-05151384M369
CoexpressionGSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_DN

RNF213 MYCBP2 RPS4X SYNE1

1.24e-04177384M7632
CoexpressionBILANGES_SERUM_AND_RAPAMYCIN_SENSITIVE_GENES

RPS4Y2 RPS4X RPS4Y1

1.63e-0473383MM1304
CoexpressionTABULA_MURIS_SENIS_LUNG_NK_CELL_AGEING

RPS4Y2 RPS4X RPS4Y1

1.77e-0475383MM3759
CoexpressionTABULA_MURIS_SENIS_KIDNEY_BRUSH_CELL_AGEING

RPS4Y2 RPS4X RPS4Y1

1.77e-0475383MM3718
CoexpressionGSE17301_CTRL_VS_48H_IFNA2_STIM_CD8_TCELL_DN

MACF1 SETD1B KIAA0753 BRD9

1.83e-04196384M8034
CoexpressionKAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_UP

EML5 CYP2J2 MYCBP2 RPS4X

1.98e-04200384M3012
CoexpressionKIM_MYC_AMPLIFICATION_TARGETS_UP

EEF2K GPATCH4 MYCBP2 RPS4X

2.06e-04202384M8445
CoexpressionTABULA_MURIS_SENIS_THYMUS_PROFESSIONAL_ANTIGEN_PRESENTING_CELL_AGEING

RPS4Y2 RPS4X RPS4Y1

2.22e-0481383MM3848
CoexpressionTABULA_MURIS_SENIS_KIDNEY_KIDNEY_COLLECTING_DUCT_PRINCIPAL_CELL_AGEING

RPS4Y2 MACF1 MYCBP2 RPS4X RPS4Y1

2.50e-04394385MM3724
CoexpressionLAKE_ADULT_KIDNEY_C29_UNKNOWN_NOVEL_PT_CFH_POS_SUBPOPULATION_S2

MACF1 THRB SYNE1

2.65e-0486383M39248
CoexpressionAtlaskidney single cell_e11.5_MetanephMesench_StemCellamp_k-means-cluster#3_top-relative-expression-ranked_500

SMARCA1 RPS4Y2 ZBED4 RPS4X

5.55e-05120374gudmap_kidney single cell_e11.5_MetanephMesench_Scamp_k3_500
CoexpressionAtlasB cells, proB.FrA.BM, CD19- IgM- CD43+ CD24- AA4.1+ CD45R+ CD117+ IL7R+, Bone marrow, avg-1

CCDC125 EEF2K CYP2J2 F5 SYNE1 ZNF652

5.69e-05395376GSM538351_500
CoexpressionAtlasdev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_100

SMARCA1 RNF213

1.32e-0410372gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k3_100
CoexpressionAtlasdev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#1_top-relative-expression-ranked_100

SMARCA1 RNF213

1.32e-0410372gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k1_100
ToppCellLPS_IL1RA_TNF-Hematopoietic_Myeloid-Granulocytic_cells-Mast-cells|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CCDC125 GPATCH4 F5 RPS4X RPS4Y1

8.20e-07199395892ca0dc9928d3985bf99de8afc68c06d22e6e2e
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

PKHD1 RNF213 MACF1 SYNE1

5.88e-06135394ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 THRB F5 SYNE1

1.87e-051813945f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 THRB F5 SYNE1

1.87e-05181394c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMH+-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

RNF213 MACF1 RPS4Y1 SYNE1

2.03e-05185394097d628f92e13250c15b550f2fd1f4225fc07558
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 THRB F5 SYNE1

2.03e-0518539434fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 THRB F5 SYNE1

2.03e-051853948816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 THRB F5 SYNE1

2.17e-05188394874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 THRB F5 SYNE1

2.17e-05188394b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell3'_v3-blood-Lymphocytic_T_CD8-Tem/emra_CD8|blood / Manually curated celltypes from each tissue

RNF213 MACF1 RPS4Y1 SYNE1

2.26e-051903945624f711b34132081f93fa70702316962e3e3c64
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

RNF213 MACF1 MYCBP2 ARHGAP11B

2.30e-051913949454f642c3621370fa23640b631301346b300950
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-SST-MGE1-4|World / Primary Cells by Cluster

ZNF536 THRB MYCBP2 RPS4Y1

2.40e-051933942eb6e4cff4fe3ce564c1581f6f7df4834895aaa9
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF213 MACF1 RPS4X SYNE1

2.55e-051963940f3c7fd450aaa1f866b8558692534c0ea2a34e75
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RNF213 MACF1 RPS4X SYNE1

2.55e-051963944e1f8828413896ab8a4ec92a89d6789e8e37e05a
ToppCellmild-MAIT|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RNF213 MACF1 SYNE1 ZNF652

2.71e-05199394cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

RNF213 MACF1 SYNE1 PWP2

2.76e-052003942281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

RNF213 MACF1 SYNE1

1.62e-0412139319333a660800b583fa27b495c1f7828e6636a257
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 F5 SYNE1

2.86e-04147393989a48bda98fbff398985397a6b1189a4cbc80e7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 F5 SYNE1

2.86e-04147393f6681c849c4c06154548bd29a094f202d1c946c2
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

RNF213 MACF1 SYNE1

3.41e-04156393afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 F5 SYNE1

3.41e-04156393abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 F5 SYNE1

3.41e-04156393dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM7A F5 SYNE1

3.47e-041573930673c7161c25feceee8f1e5fd237171576c42c6b
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM7A F5 SYNE1

3.47e-04157393d307d0b48af35e0e1af41ecd3ebf91be8fd29dc0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 F5 SYNE1

3.54e-04158393e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 F5 SYNE1

3.54e-04158393d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal-GABAergic_neurons|GW16 / Sample Type, Dataset, Time_group, and Cell type.

ZNF536 THRB MYCBP2

3.95e-041643934d7b2d0980fb4f47721fa2891151e2bd892ccb91
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM7A F5 SYNE1

4.46e-04171393ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM7A F5 SYNE1

4.46e-0417139397ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RNF213 MACF1 SYNE1

4.46e-041713932e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellpdx-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CCDC125 THRB COMMD1

4.85e-041763931e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM7A F5 SYNE1

4.93e-04177393065bebd22031f143e90a407f952b444a3f8818c7
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF213 MACF1 SYNE1

4.93e-04177393d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF213 MACF1 SYNE1

4.93e-04177393f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

RNF213 MACF1 SYNE1

4.93e-04177393936ab2b180a052387124f68d0c7f41c0b164e748
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RNF213 MACF1 SYNE1

4.93e-04177393d5aeda113afaa2425874394610344570c9078478
ToppCellfacs-Marrow-Granulocytes-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM7A F5 SYNE1

4.93e-04177393eb304f20aab075bd17aa3aef819386c0e1a235bd
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

RNF213 MACF1 SYNE1

4.93e-041773936978a22fef40c8b455342373abe7593f5ede0fa4
ToppCelldroplet-Limb_Muscle-nan-24m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF536 F5 KIAA0753

5.01e-04178393f2002a5c4758d0af6c1880ca12f0af0d5e8888e4
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 ZNF536 THRB

5.01e-04178393544379f5a6145429762258d426b876bb36c112f5
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MACF1 KDM7A ATP7B

5.09e-041793936e965e424eebef50f0202cff75f458be395cfca1
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

ZNF536 THRB SYNE1

5.09e-04179393e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCelldroplet-Fat-Bat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PALMD ATAD5 KIAA0753

5.09e-041793939863ab3ceb160a4b1d9790033a4ac48845863d65
ToppCelldroplet-Fat-Bat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PALMD ATAD5 KIAA0753

5.09e-04179393dfe110add7228cd834b35916cbcc849769a01bb9
ToppCelldroplet-Fat-Bat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PALMD ATAD5 KIAA0753

5.09e-04179393e6224864eb76a2e9c1fc0c61513d9e936bb5c72c
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MACF1 MYCBP2 BRD9

5.18e-04180393423454e3390080ae03bb3cbb267255ebfe4df080
ToppCellCV-Healthy-2|CV / Virus stimulation, Condition and Cluster

SMARCA1 GPATCH4 BRD9

5.18e-04180393e182e5c495dd82d4fcbf1a920086c70b064801f3
ToppCellMatrixFB-Fibroblast-A|MatrixFB / shred on cell class and cell subclass (v4)

RPS4Y2 MACF1 RPS4X

5.18e-04180393adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MACF1 MYCBP2 BRD9

5.18e-04180393dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MACF1 MYCBP2 ATAD5

5.35e-041823931710eab3037a87609d21838be2d2d29c3bc36651
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MACF1 MYCBP2 ATAD5

5.35e-04182393e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCellCOVID-19_Mild-NK_activated|COVID-19_Mild / Disease condition and Cell class

RNF213 MACF1 SYNE1

5.43e-0418339322bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

RNF213 MACF1 SYNE1

5.43e-04183393f593a89b0aa8fffdfa403769916facfd30358521
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMK+-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

RNF213 RPS4Y1 SYNE1

5.43e-0418339379defd22b3194dad16db55b9bdd220c09c1e6b90
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-SST-MGE1-3|World / Primary Cells by Cluster

ZNF536 THRB RPS4X

5.52e-04184393907ba412166bcb0526c5be0b06a76b6bd37c5a35
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SMARCA1 ZNF536 PALMD

5.52e-04184393a6dee97ee4ef9d89e11d17339e0dadaea1210ce5
ToppCellremission-CD8+_T_naive|remission / disease stage, cell group and cell class

ATP7B RPS4X RPS4Y1

5.52e-04184393fe20fa4457d4a4a75689978275b0afb5f6243faf
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

RNF213 MACF1 SYNE1

5.52e-04184393791f1bcb954aadc63d4117c400537d036f68734d
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF536 THRB SYNE1

5.61e-04185393e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCellnormal-na-Lymphocytic_NK-NK_dim-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

RNF213 RPS4Y1 SYNE1

5.61e-04185393b1a8a8c4d0fc7605eabc17dcb6bd9e8ab4fd578c
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

RNF213 MACF1 MYCBP2

5.61e-04185393a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

RNF213 MACF1 MYCBP2

5.69e-041863938571956890fc9894d766ba294a28e376b4aba428
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SMARCA1 EEF2K SYNE1

5.78e-04187393ac8e092b37e042975e2ee057d3f7c6821e58e8b5
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SMARCA1 EEF2K SYNE1

5.78e-04187393d591a3c216997663ab77710fed0d230ffc37e41a
ToppCellCOVID-19_Mild-Neu_4|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

EEF2K TBC1D9B PWP2

5.78e-04187393714851e757c71c559ee6413a3f61d6c117c79ad2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

THRB RPS4Y1 SYNE1

5.78e-04187393cfdc1585c80d2bb475d9145395fb50a88c53f838
ToppCelldroplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS4Y2 ATAD5 SYNE1

5.78e-0418739314c239af77116d28d511dea754b6150d20488080
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_dim-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RNF213 RPS4Y1 SYNE1

5.78e-041873930bca79cea4886b66350c56c61859bd71e1e7a85c
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SMARCA1 EEF2K SYNE1

5.78e-04187393d1dc8c9a2c2cd10c640257161a75e7730ec5bb41
ToppCell3'_v3-blood-Lymphocytic_T_CD8-Trm/em_CD8|blood / Manually curated celltypes from each tissue

RNF213 RPS4Y1 SYNE1

5.87e-0418839321730497f95dc271e4cdfaaf1da8b9ac6eec2ded
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CCDC125 PKHD1 THRB

5.97e-041893937659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 THRB SYNE1

5.97e-04189393830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell3'_v3-blood-Lymphocytic_T_CD8|blood / Manually curated celltypes from each tissue

RNF213 RPS4Y1 SYNE1

6.06e-041903935dca8654964c41580fa3b094579fe7cb296d406f
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MACF1 PALMD MYCBP2

6.06e-04190393d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

MACF1 THRB RPS4Y1

6.06e-0419039362a3ec1ae0829602b0569cc051210551644f1d46
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNF213 MACF1 SYNE1

6.06e-04190393d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-ELP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MACF1 MYCBP2 RPS4X

6.24e-0419239338ec82aa2ec4f2c0a843e83f7fe54f6b2483ca3d
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMH+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RNF213 RPS4Y1 SYNE1

6.24e-04192393fdc741e1846cfd8ed741b160e3c611c310c5d36d
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CCDC125 PKHD1 THRB

6.24e-04192393b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RNF213 MACF1 SYNE1

6.24e-04192393ed1fb700d3e8f00495727d61e164fc0b70274fd0
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RNF213 RPS4Y1 SYNE1

6.24e-04192393ab88ea7723f0fa3b39611981c043445f27425404
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RNF213 MACF1 SYNE1

6.24e-041923936779b0294bb058e748e22b795b6a381c4add37e9
ToppCellhuman_hepatoblastoma-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PALMD THRB F5

6.24e-04192393e785135262f4c9cc66c403bf362bb34643b212c5
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-SST-MGE1|World / Primary Cells by Cluster

ZNF536 THRB RPS4X

6.24e-04192393bcc499f4c7ba2898ecd9c47bf68c92ed359b81ba
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RNF213 MACF1 SYNE1

6.34e-041933936e1498153a7766c03fddbda1701dbf1596d21736
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA1 ZNF536 F5

6.34e-041933936995ee29bf403a71247de92a37dfd851be5acf2e
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MACF1 ZBED4 SYNE1

6.34e-04193393a594f89a18273797506287d9e22f72abe53e4920
ToppCellCOVID-19_Severe-CD8+_T_activated|World / disease group, cell group and cell class

RNF213 RPS4Y1 SYNE1

6.34e-04193393ddc1db516568e03be8e82b2ca770c67756418185
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RNF213 MACF1 SYNE1

6.34e-041933939337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-22|World / Primary Cells by Cluster

PALMD RPS4X RPS4Y1

6.34e-041933933b927d4b8ecb21a408424ef91a23746c21741f49
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RNF213 MACF1 SYNE1

6.34e-04193393fce4f805e53669acb4c188f87ac7d84408c0c218
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RNF213 RPS4X SYNE1

6.43e-041943939588a9b4baebbae08e13d201d4b9dfcf0e6521fb
ToppCellsevere_COVID-19-CD4+_CTL|World / disease group, cell group and cell class (v2)

RNF213 RPS4Y1 SYNE1

6.43e-04194393bdafc1173b7b8cde8714573fbeee5394a2484a5f
ToppCellIIF-Lymphocyte-T_NK-CD8_TEM|IIF / Disease, Lineage and Cell Type

RNF213 RPS4X SYNE1

6.43e-04194393f4f7c85963ba52ee7ca2ef5657e60680fe6332fe
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 RNF213 SYNE1

6.43e-04194393e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF536 F5 SYNE1

6.43e-041943931374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCellCV-Moderate-0|CV / Virus stimulation, Condition and Cluster

RPS4X RPS4Y1 SYNE1

6.43e-041943939ff69139dae007fcc349daefcb5021defb0e0d2a
ToppCellCOVID-19_Severe-CD8+_Tem|COVID-19_Severe / Disease condition and Cell class

RNF213 MACF1 SYNE1

6.53e-04195393ff7ae62393e1c858a10592db8e6d9f36b8bae396
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMH+|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RNF213 RPS4Y1 SYNE1

6.53e-041953931a7c2c4cf30df435770794a989be438579bf98f2
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

RNF213 MACF1 SYNE1

6.53e-041953939990440bda7fac5d00ef80444fab07459be625e1
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

RNF213 MACF1 SYNE1

1.79e-0450243GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
Diseasethrombosis (is_implicated_in)

FGB F5

1.59e-0415372DOID:0060903 (is_implicated_in)
Diseasemyocardial infarction (is_implicated_in)

FGB CYP2J2 F5

2.62e-0499373DOID:5844 (is_implicated_in)
DiseaseLiver Cirrhosis

ATP7B COMMD1 F5

2.94e-04103373C0023890
DiseaseFibrosis, Liver

ATP7B COMMD1 F5

3.12e-04105373C0239946
Diseasemean corpuscular hemoglobin concentration

MACF1 GTF2A1 SETD1B THRB ATP7B POLR1A COMMD1

3.90e-041105377EFO_0004528
DiseaseD dimer measurement

FGB F5

6.51e-0430372EFO_0004507
Diseasepulmonary hypertension (is_implicated_in)

CYP2J2 F5

6.51e-0430372DOID:6432 (is_implicated_in)
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

PEPD PKHD1 MACF1 POLR1A

1.09e-03364374EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Diseaseend stage renal disease (is_implicated_in)

FGB F5

1.22e-0341372DOID:783 (is_implicated_in)
Diseasetotal cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement

SETD1B ZNF652

1.73e-0349372EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612

Protein segments in the cluster

PeptideGeneStartEntry
HKITMKEEWHKFIQL

ATAD5

1481

Q96QE3
WKKLKLFVSHMIDKH

CYP2J2

251

P51589
MGKKHKKHKAEWRSS

BRD9

1

Q9H8M2
LDHKMEIKQWKKSFL

ATP7B

641

P35670
TWMGKIHSKEHFKEK

PEPD

106

P12955
VLLHHWKALKKVNMK

ARHGAP11B

241

Q3KRB8
LKHQHLKKKALREKW

PALMD

36

Q9NP74
GVKALHTALKLWMKK

KDM7A

431

Q6ZMT4
KKKKRWHHEEEKMGV

GPATCH4

291

Q5T3I0
SWSFHKLKTMKHLLL

FGB

6

P02675
KWVNKHLMKVRKHIN

MACF1

86

Q9UPN3
HKKATKWMNWKHLKE

CCDC125

351

Q86Z20
KFWKSHKTKIRESLM

COMMD1

96

Q8N668
FKEAWKHAIQKAKHM

EEF2K

81

O00418
KLITAGIKHMKFWRK

EML5

831

Q05BV3
IWKKHYIQMVKELHI

FBXO16

151

Q8IX29
KMFWEKKIEHHARHL

FAM240C

26

A0A1B0GVR7
ESKSKLIALFWKAHM

POLR1A

186

O95602
EMVIKEKSVFKKFHW

SMARCA1

291

P28370
LKWAFSKHETAKNKM

SYNE1

2121

Q8NF91
AKHRFSWMKLLAHKV

F5

876

P12259
KKHLKRVAAPKHWML

RPS4Y1

6

P22090
KKHLKRVAAPKHWML

RPS4Y2

6

Q8TD47
KKKLKFCKSHIHDWG

SETD1B

1826

Q9UPS6
KKAALMHKWPLKEIS

MYCBP2

346

O75592
KSMVHKKAWLISAKQ

PKHD1

236

P08F94
KKHLKRVAAPKHWML

RPS4X

6

P62701
LSPHKIKHTKKSWAM

KIAA0753

286

Q2KHM9
KGAKEKMKEESWHIH

TBC1D9B

471

Q66K14
KIHRSKNKWKFHLKD

GTF2A1

341

P52655
SAFMKHLKKLWKALD

RNF213

1486

Q63HN8
LKLHNKKLAAFWLMK

RMDN1

271

Q96DB5
LWTHKLLMLHGQKLK

PWP2

821

Q15269
KHHVTHFWPKLLMKV

THRB

411

P10828
WFLKNHMKVHLNKLS

ZNF536

386

O15090
HREKLLKKMQSLWEK

TRIM49D1

136

C9J1S8
TLEPLHTLLHMKWKK

TRPV3

421

Q8NET8
HTLLHMKWKKFAKHM

TRPV3

426

Q8NET8
KSFKKLWSLHEHIKI

ZNF652

306

Q9Y2D9
KKVMKRLKSEVWHHF

ZBED4

451

O75132