Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	sphingolipid floppase activity	ABCA1 ABCB1 ABCB4	2.11e-07	4	76	3	GO:0046623
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC25A3 ATP5MG ABCA1 SLC25A21 SLC9A1 SLC12A1 SLC25A5 ABCB11 SLC7A6 ABCC6 ABCB1 ABCB4	2.33e-07	477	76	12	GO:0022804
GeneOntologyMolecularFunction	sphingolipid transporter activity	CPTP ABCA1 ABCB1 ABCB4	8.96e-07	20	76	4	GO:0046624
GeneOntologyMolecularFunction	transporter activity	SLC25A3 CPTP ATP5MG GJA1 ANO2 ABCA1 SLC25A21 SLC9A1 SIDT2 SLC12A1 SLC25A5 SLC22A13 ABCB11 SLC7A6 SLC48A1 ABCC6 ABCB1 ABCB4	1.17e-06	1289	76	18	GO:0005215
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA1 ABCB11 ABCC6 ABCB1 ABCB4	1.17e-06	49	76	5	GO:0140359
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC25A3 ATP5MG GJA1 ANO2 ABCA1 SLC25A21 SLC9A1 SIDT2 SLC12A1 SLC25A5 SLC22A13 ABCB11 SLC7A6 SLC48A1 ABCC6 ABCB1 ABCB4	1.61e-06	1180	76	17	GO:0022857
GeneOntologyMolecularFunction	phosphatidylcholine floppase activity	ABCA1 ABCB1 ABCB4	2.93e-06	8	76	3	GO:0090554
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ATP5MG ABCA1 ABCB11 ABCC6 ABCB1 ABCB4	3.69e-06	109	76	6	GO:0042626
GeneOntologyMolecularFunction	phospholipid transporter activity	CPTP ANO2 ABCA1 ABCB1 ABCB4	9.17e-06	74	76	5	GO:0005548
GeneOntologyMolecularFunction	ABC-type xenobiotic transporter activity	ABCB11 ABCC6 ABCB1	2.33e-05	15	76	3	GO:0008559
GeneOntologyMolecularFunction	floppase activity	ABCA1 ABCB1 ABCB4	2.86e-05	16	76	3	GO:0140328
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ANO2 ABCA1 ABCB1 ABCB4	4.23e-05	51	76	4	GO:0140303
GeneOntologyMolecularFunction	ceramide floppase activity	ABCB1 ABCB4	4.28e-05	3	76	2	GO:0099038
GeneOntologyMolecularFunction	phosphatidylcholine transporter activity	ABCA1 ABCB1 ABCB4	5.77e-05	20	76	3	GO:0008525
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ATP5MG ABCA1 ABCB11 ABCC6 ABCB1 ABCB4	6.01e-05	178	76	6	GO:0015399
GeneOntologyMolecularFunction	lipid transporter activity	CPTP ANO2 ABCA1 ABCB11 ABCB1 ABCB4	1.02e-04	196	76	6	GO:0005319
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	GJA1 SLC25A21 SLC25A5 SLC22A13 ABCB11 SLC7A6 ABCB1	1.25e-04	293	76	7	GO:0008514
GeneOntologyMolecularFunction	activin receptor activity, type I	TGFBR1 ACVR1C	1.42e-04	5	76	2	GO:0016361
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ABCA1 ABCB1 ABCB4	1.62e-04	28	76	3	GO:0140326
GeneOntologyMolecularFunction	xenobiotic transmembrane transporter activity	ABCB11 ABCC6 ABCB1	2.91e-04	34	76	3	GO:0042910
GeneOntologyMolecularFunction	activin receptor activity	TGFBR1 ACVR1C	5.06e-04	9	76	2	GO:0017002
GeneOntologyMolecularFunction	activin binding	TGFBR1 ACVR1C	9.21e-04	12	76	2	GO:0048185
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC25A3 SLC25A21 SLC9A1 SLC12A1 SLC25A5 SLC7A6	9.24e-04	296	76	6	GO:0015291
GeneOntologyMolecularFunction	BMP receptor binding	ELAPOR2 ACVR1C	1.09e-03	13	76	2	GO:0070700
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	SLC25A21 SLC22A13 ABCB11 SLC7A6 ABCB1	1.16e-03	207	76	5	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	SLC25A21 SLC22A13 ABCB11 SLC7A6 ABCB1	1.19e-03	208	76	5	GO:0005342
GeneOntologyMolecularFunction	efflux transmembrane transporter activity	GJA1 ABCB1	1.66e-03	16	76	2	GO:0015562
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	RAP1GDS1 RAPGEF4 PSD3 ALS2 TIAM2	1.88e-03	231	76	5	GO:0005085
GeneOntologyMolecularFunction	antiporter activity	SLC25A21 SLC9A1 SLC25A5 SLC7A6	1.91e-03	138	76	4	GO:0015297
GeneOntologyMolecularFunction	protein tyrosine kinase activity	HIPK3 FRK AATK LCK	2.28e-03	145	76	4	GO:0004713
GeneOntologyMolecularFunction	transmembrane receptor protein serine/threonine kinase activity	TGFBR1 ACVR1C	2.60e-03	20	76	2	GO:0004675
GeneOntologyMolecularFunction	polypeptide N-acetylgalactosaminyltransferase activity	GALNT17 GALNT16	2.60e-03	20	76	2	GO:0004653
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	SLC25A3 ANO2 SLC12A1 ABCC6	4.13e-03	171	76	4	GO:0015103
GeneOntologyMolecularFunction	phosphatidylinositol phospholipase C activity	GDPD5 PLCB4	4.38e-03	26	76	2	GO:0004435
GeneOntologyMolecularFunction	transmembrane receptor protein serine/threonine kinase binding	ELAPOR2 ACVR1C	4.72e-03	27	76	2	GO:0070696
GeneOntologyBiologicalProcess	sphingolipid translocation	ABCA1 ABCB1 ABCB4	4.78e-07	5	76	3	GO:0099039
GeneOntologyBiologicalProcess	organophosphate ester transport	CPTP GJA1 ABCA1 SLC25A5 ABCC6 ABCB1 ABCB4	2.25e-06	162	76	7	GO:0015748
GeneOntologyBiologicalProcess	xenobiotic transport	GJA1 ABCB11 ABCC6 ABCB1 ABCB4	3.82e-06	64	76	5	GO:0042908
GeneOntologyBiologicalProcess	organic anion transport	CPTP GJA1 SLC25A21 SLC25A5 SLC22A13 ABCB11 SLC7A6 ABCC6 ABCB1 ABCB4	1.88e-05	515	76	10	GO:0015711
GeneOntologyBiologicalProcess	amide transport	CPTP GJA1 ABCA1 SIDT2 SLC12A1 RAPGEF4 ACVR1C ABCB1 ABCB4	2.36e-05	420	76	9	GO:0042886
GeneOntologyBiologicalProcess	ceramide transport	CPTP ABCB1 ABCB4	3.77e-05	18	76	3	GO:0035627
GeneOntologyBiologicalProcess	regulation of T cell mediated cytotoxicity directed against tumor cell target	SLC22A13 MUC4	4.01e-05	3	76	2	GO:0002852
GeneOntologyBiologicalProcess	ceramide translocation	ABCB1 ABCB4	4.01e-05	3	76	2	GO:0099040
GeneOntologyBiologicalProcess	xenobiotic transmembrane transport	ABCB11 ABCC6 ABCB4	4.46e-05	19	76	3	GO:0006855
GeneOntologyBiologicalProcess	ATP transport	GJA1 SLC25A5 ABCC6	8.07e-05	23	76	3	GO:0015867
GeneOntologyBiologicalProcess	carboxylic acid transport	GJA1 SLC25A21 SLC22A13 ABCB11 SLC7A6 ABCC6 ABCB1 ABCB4	1.32e-04	410	76	8	GO:0046942
GeneOntologyBiologicalProcess	organic acid transport	GJA1 SLC25A21 SLC22A13 ABCB11 SLC7A6 ABCC6 ABCB1 ABCB4	1.36e-04	412	76	8	GO:0015849
GeneOntologyBiologicalProcess	T cell mediated cytotoxicity directed against tumor cell target	SLC22A13 MUC4	1.99e-04	6	76	2	GO:0002419
GeneOntologyCellularComponent	apical plasma membrane	TGFBR1 GJA1 SLC9A1 KL SLC12A1 SLC22A13 RAPGEF4 ABCB11 PLEC MUC4 ABCC6 ABCB1 ABCB4	2.04e-08	487	76	13	GO:0016324
GeneOntologyCellularComponent	apical part of cell	TGFBR1 GJA1 SLC9A1 KL SLC12A1 EPB41L4B SLC22A13 RAPGEF4 ABCB11 PLEC MUC4 ABCC6 ABCB1 ABCB4	2.50e-08	592	76	14	GO:0045177
GeneOntologyCellularComponent	intercellular canaliculus	ABCB11 ABCB1 ABCB4	3.82e-06	9	76	3	GO:0046581
GeneOntologyCellularComponent	activin receptor complex	TGFBR1 ACVR1C	1.94e-04	6	76	2	GO:0048179
GeneOntologyCellularComponent	Golgi membrane	GJA1 TLCD3B GALNT17 IER3IP1 ABCB11 LMTK3 GOLT1A GALNT16 ABCB1 ABCB4	2.74e-04	721	76	10	GO:0000139
GeneOntologyCellularComponent	cell-cell junction	TGFBR1 MAGI1 GJA1 SLC9A1 EPB41L4B ABCB11 LCK ABCB1 ABCB4	2.87e-04	591	76	9	GO:0005911
GeneOntologyCellularComponent	basal plasma membrane	TGFBR1 ABCA1 SLC9A1 RAPGEF4 ABCB11 PLEC ABCC6	3.02e-04	354	76	7	GO:0009925
GeneOntologyCellularComponent	membrane raft	TGFBR1 GJA1 ABCA1 SLC9A1 SLC25A5 LCK ABCB4	3.46e-04	362	76	7	GO:0045121
GeneOntologyCellularComponent	membrane microdomain	TGFBR1 GJA1 ABCA1 SLC9A1 SLC25A5 LCK ABCB4	3.57e-04	364	76	7	GO:0098857
GeneOntologyCellularComponent	basal part of cell	TGFBR1 ABCA1 SLC9A1 RAPGEF4 ABCB11 PLEC ABCC6	4.48e-04	378	76	7	GO:0045178
GeneOntologyCellularComponent	organelle envelope	IVD SLC25A3 CPTP ATP5MG GJA1 SLC25A21 HSP90B2P SLC25A5 EXD2 DUSP2 MRGPRF MRPL41 PLEC GOLT1A	5.96e-04	1435	76	14	GO:0031967
GeneOntologyCellularComponent	basolateral plasma membrane	TGFBR1 ABCA1 SLC9A1 RAPGEF4 ABCB11 ABCC6	1.09e-03	320	76	6	GO:0016323
GeneOntologyCellularComponent	mitochondrial membrane	IVD SLC25A3 ATP5MG GJA1 SLC25A21 HSP90B2P SLC25A5 EXD2 MRPL41 PLEC	1.13e-03	866	76	10	GO:0031966
GeneOntologyCellularComponent	tight junction	TGFBR1 MAGI1 GJA1 EPB41L4B	1.66e-03	139	76	4	GO:0070160
GeneOntologyCellularComponent	mitochondrial envelope	IVD SLC25A3 ATP5MG GJA1 SLC25A21 HSP90B2P SLC25A5 EXD2 MRPL41 PLEC	1.67e-03	912	76	10	GO:0005740
GeneOntologyCellularComponent	anchoring junction	TGFBR1 MAGI1 GJA1 SLC9A1 EPB41L4B ABCB11 PLEC LCK ABCB1 ABCB4	2.74e-03	976	76	10	GO:0070161
MousePheno	nephrocalcinosis	KL SLC12A1 ABCC6	8.98e-05	20	62	3	MP:0003197
MousePheno	decreased abdominal adipose tissue amount	NQO1 XDH MBD5	1.38e-04	23	62	3	MP:0008853
MousePheno	abnormal endocrine gland physiology	HIPK3 SIDT2 KL RAP1GDS1 RAPGEF4 C1QTNF9 XDH LCK	1.90e-04	363	62	8	MP:0013561
MousePheno	calcified skin	KL ABCC6	1.92e-04	5	62	2	MP:0003196
MousePheno	decreased skin turgor	RAP1GDS1 SLC12A1	1.92e-04	5	62	2	MP:0003653
MousePheno	intrahepatic cholestasis	ABCB11 ABCB4	1.92e-04	5	62	2	MP:0005415
MousePheno	abnormal bile canaliculus morphology	ABCB11 ABCB4	1.92e-04	5	62	2	MP:0008991
MousePheno	abnormal gland physiology	HIPK3 GJA1 SLC9A1 SIDT2 KL RAP1GDS1 RAPGEF4 C1QTNF9 XDH LCK STAT6	2.01e-04	691	62	11	MP:0002164
Domain	ABC_transporter_CS	ABCA1 ABCB11 ABCC6 ABCB1 ABCB4	6.03e-07	42	73	5	IPR017871
Domain	ABC_tran	ABCA1 ABCB11 ABCC6 ABCB1 ABCB4	1.19e-06	48	73	5	PF00005
Domain	ABC_TRANSPORTER_2	ABCA1 ABCB11 ABCC6 ABCB1 ABCB4	1.19e-06	48	73	5	PS50893
Domain	ABC_TRANSPORTER_1	ABCA1 ABCB11 ABCC6 ABCB1 ABCB4	1.32e-06	49	73	5	PS00211
Domain	ABC_transporter-like	ABCA1 ABCB11 ABCC6 ABCB1 ABCB4	1.47e-06	50	73	5	IPR003439
Domain	ABC_membrane	ABCB11 ABCC6 ABCB1 ABCB4	2.15e-06	24	73	4	PF00664
Domain	ABC_TM1F	ABCB11 ABCC6 ABCB1 ABCB4	4.10e-06	28	73	4	PS50929
Domain	ABC1_TM_dom	ABCB11 ABCC6 ABCB1 ABCB4	4.10e-06	28	73	4	IPR011527
Domain	AAA+_ATPase	ABCA1 ABCB11 ABCC6 ABCB1 ABCB4	2.50e-04	144	73	5	IPR003593
Domain	AAA	ABCA1 ABCB11 ABCC6 ABCB1 ABCB4	2.50e-04	144	73	5	SM00382
Domain	GS	TGFBR1 ACVR1C	3.12e-04	7	73	2	SM00467
Domain	GS_dom	TGFBR1 ACVR1C	3.12e-04	7	73	2	IPR003605
Domain	GS	TGFBR1 ACVR1C	3.12e-04	7	73	2	PS51256
Domain	TGF_beta_GS	TGFBR1 ACVR1C	3.12e-04	7	73	2	PF08515
Domain	PROTEIN_KINASE_TYR	FRK AATK LCK LMTK3	5.66e-04	97	73	4	PS00109
Domain	Activin_recp	TGFBR1 ACVR1C	6.64e-04	10	73	2	IPR000472
Domain	Activin_recp	TGFBR1 ACVR1C	6.64e-04	10	73	2	PF01064
Domain	TGFB_receptor	TGFBR1 ACVR1C	9.70e-04	12	73	2	IPR000333
Domain	SOLCAR	SLC25A3 SLC25A21 SLC25A5	1.17e-03	53	73	3	PS50920
Domain	-	SLC25A3 SLC25A21 SLC25A5	1.17e-03	53	73	3	1.50.40.10
Domain	Mitochondrial_sb/sol_carrier	SLC25A3 SLC25A21 SLC25A5	1.17e-03	53	73	3	IPR018108
Domain	Mito_carr	SLC25A3 SLC25A21 SLC25A5	1.17e-03	53	73	3	PF00153
Domain	Mt_carrier_dom	SLC25A3 SLC25A21 SLC25A5	1.17e-03	53	73	3	IPR023395
Domain	Pkinase_Tyr	FRK AATK LCK ACVR1C	1.64e-03	129	73	4	PF07714
Domain	PROTEIN_KINASE_ATP	HIPK3 TGFBR1 FRK AATK LCK ACVR1C LMTK3	2.08e-03	459	73	7	PS00107
Domain	Ser-Thr/Tyr_kinase_cat_dom	FRK AATK LCK ACVR1C	2.09e-03	138	73	4	IPR001245
Domain	PROTEIN_KINASE_DOM	HIPK3 TGFBR1 FRK AATK LCK ACVR1C LMTK3	3.10e-03	493	73	7	PS50011
Domain	AA-permease/SLC12A_dom	SLC12A1 SLC7A6	3.31e-03	22	73	2	IPR004841
Domain	AA_permease	SLC12A1 SLC7A6	3.31e-03	22	73	2	PF00324
Domain	Protein_kinase_ATP_BS	HIPK3 TGFBR1 FRK AATK LCK ACVR1C	3.64e-03	379	73	6	IPR017441
Domain	-	GDPD5 PLCB4	4.26e-03	25	73	2	3.20.20.190
Domain	Ricin_B_lectin	GALNT17 GALNT16	4.26e-03	25	73	2	PF00652
Domain	PLC-like_Pdiesterase_TIM-brl	GDPD5 PLCB4	4.26e-03	25	73	2	IPR017946
Domain	RICIN	GALNT17 GALNT16	5.33e-03	28	73	2	SM00458
Domain	RICIN_B_LECTIN	GALNT17 GALNT16	5.33e-03	28	73	2	PS50231
Domain	Ricin_B_lectin	GALNT17 GALNT16	6.11e-03	30	73	2	IPR000772
Domain	Glycos_transf_2	GALNT17 GALNT16	6.11e-03	30	73	2	PF00535
Domain	Glyco_trans_2-like	GALNT17 GALNT16	6.11e-03	30	73	2	IPR001173
Domain	Tyr_kinase_AS	FRK AATK LCK	6.49e-03	97	73	3	IPR008266
Domain	Mit_carrier	SLC25A21 SLC25A5	6.93e-03	32	73	2	IPR002067
Domain	SH2	FRK LCK STAT6	7.26e-03	101	73	3	PF00017
Pathway	KEGG_ABC_TRANSPORTERS	ABCA1 ABCB11 ABCC6 ABCB1 ABCB4	1.04e-06	44	59	5	M11911
Pathway	BIOCARTA_MRP_PATHWAY	ABCB11 ABCB1 ABCB4	1.38e-06	6	59	3	M22078
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	ABCA1 ABCB11 ABCB1 ABCB4	6.99e-06	30	59	4	MM15866
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	ABCA1 ABCB11 ABCB1 ABCB4	1.17e-05	34	59	4	M16393
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	ABCA1 ABCB11 ABCB1 ABCB4	1.32e-05	35	59	4	M39488
Pathway	BIOCARTA_MRP_PATHWAY	ABCB11 ABCB1	1.71e-04	5	59	2	MM1586
Pathway	WP_DISORDERS_OF_BILE_ACID_SYNTHESIS_AND_BILIARY_TRANSPORT	ABCB11 ABCB1 ABCB4	2.36e-04	29	59	3	M45551
Pathway	REACTOME_ABC_TRANSPORTER_DISORDERS	ABCA1 ABCB11 ABCC6 ABCB4	3.13e-04	78	59	4	M27473
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	ABCA1 ABCB11 ABCB1	3.47e-04	33	59	3	MM1448
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	CPTP ANO2 ABCA1 SLC9A1 SLC12A1 SLC25A5 SLC7A6 ABCC6 ABCB1 ABCB4	4.75e-04	681	59	10	MM14985
Pubmed	Identification of HAX-1 as a protein that binds bile salt export protein and regulates its abundance in the apical membrane of Madin-Darby canine kidney cells.	ABCB11 ABCB1 ABCB4	1.00e-07	5	76	3	15159385
Pubmed	Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes.	ABCB11 ABCB1 ABCB4	1.19e-06	10	76	3	12068294
Pubmed	Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.	ABCA1 ABCB11 SULT4A1 ABCC6 ABCB1 ABCB4	4.28e-06	193	76	6	19343046
Pubmed	Use of a peptide mimotope to guide the humanization of MRK-16, an anti-P-glycoprotein monoclonal antibody.	ABCB1 ABCB4	4.71e-06	2	76	2	10488067
Pubmed	Hydrophilic bile acids prevent liver damage caused by lack of biliary phospholipid in Mdr2-/- mice.	ABCB11 ABCB4	4.71e-06	2	76	2	30416103
Pubmed	Expression Analysis of ATP-Binding Cassette Transporters ABCB11 and ABCB4 in Primary Sclerosing Cholangitis and Variety of Pediatric and Adult Cholestatic and Noncholestatic Liver Diseases.	ABCB11 ABCB4	4.71e-06	2	76	2	31886153
Pubmed	Multidrug resistance gene expression and ABCB1 SNPs in plasma cell myeloma.	ABCB1 ABCB4	4.71e-06	2	76	2	21705081
Pubmed	The role of different P-glycoproteins in hepatobiliary secretion of fluorescently labeled short-chain phospholipids.	ABCB1 ABCB4	4.71e-06	2	76	2	10552998
Pubmed	Differential Coupling of Binding, ATP Hydrolysis, and Transport of Fluorescent Probes with P-Glycoprotein in Lipid Nanodiscs.	ABCB1 ABCB4	4.71e-06	2	76	2	28441502
Pubmed	Genetic dissection of the function of mammalian P-glycoproteins.	ABCB1 ABCB4	4.71e-06	2	76	2	9196326
Pubmed	Tetrahydroxylated bile acids improve cholestatic liver and bile duct injury in the Mdr2-/- mouse model of sclerosing cholangitis via immunomodulatory effects.	ABCB11 ABCB4	4.71e-06	2	76	2	35691019
Pubmed	ABCB11 and ABCB1 gene polymorphisms impact on telaprevir pharmacokinetic at one month of therapy.	ABCB11 ABCB1	4.71e-06	2	76	2	25661339
Pubmed	Effects of cellular, chemical, and pharmacological chaperones on the rescue of a trafficking-defective mutant of the ATP-binding cassette transporter proteins ABCB1/ABCB4.	ABCB1 ABCB4	4.71e-06	2	76	2	22184139
Pubmed	Isolation and expression of a complementary DNA that confers multidrug resistance.	ABCB1 ABCB4	4.71e-06	2	76	2	3022150
Pubmed	Mammalian multidrug-resistance gene: correlation of exon organization with structural domains and duplication of an ancestral gene.	ABCB1 ABCB4	4.71e-06	2	76	2	2570420
Pubmed	MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine.	ABCB1 ABCB4	4.71e-06	2	76	2	8898203
Pubmed	BSEP and MDR3: Useful Immunohistochemical Markers to Discriminate Hepatocellular Carcinomas From Intrahepatic Cholangiocarcinomas and Hepatoid Carcinomas.	ABCB11 ABCB4	4.71e-06	2	76	2	26735860
Pubmed	Combined mutations of canalicular transporter proteins cause severe intrahepatic cholestasis of pregnancy.	ABCB11 ABCB4	4.71e-06	2	76	2	16890614
Pubmed	Malaria in pregnancy regulates P-glycoprotein (P-gp/Abcb1a) and ABCA1 efflux transporters in the Mouse Visceral Yolk Sac.	ABCA1 ABCB1	4.71e-06	2	76	2	32779889
Pubmed	[Overexpression of NHE1 suppresses ABCA1 protein expression via increasing calpain activity in RAW264.7 cells].	ABCA1 SLC9A1	4.71e-06	2	76	2	28031107
Pubmed	Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes.	ABCB1 ABCB4	4.71e-06	2	76	2	2473069
Pubmed	Common genetic variation and risk of gallbladder cancer in India: a case-control genome-wide association study.	ABCB1 ABCB4	4.71e-06	2	76	2	28274756
Pubmed	A missense mutation in ABCB4 gene involved in progressive familial intrahepatic cholestasis type 3 leads to a folding defect that can be rescued by low temperature.	ABCB1 ABCB4	4.71e-06	2	76	2	19185004
Pubmed	Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression.	ABCB1 ABCB4	4.71e-06	2	76	2	18215618
Pubmed	Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury.	ABCB11 ABCB4	4.71e-06	2	76	2	17264802
Pubmed	Hepatic immunohistochemistry of bile transporters in progressive familial intrahepatic cholestasis.	ABCB11 ABCB4	4.71e-06	2	76	2	26845599
Pubmed	The role of ABC transporters' gene polymorphism in the etiology of intrahepatic cholestasis of pregnancy.	ABCB11 ABCB4	4.71e-06	2	76	2	30091450
Pubmed	Biliary transporter gene mutations in severe intrahepatic cholestasis of pregnancy: Diagnostic and management implications.	ABCB11 ABCB4	4.71e-06	2	76	2	29992621
Pubmed	What have we learnt thus far from mice with disrupted P-glycoprotein genes?	ABCB1 ABCB4	4.71e-06	2	76	2	8763339
Pubmed	ABCA1/ABCB1 Ratio Determines Chemo- and Immune-Sensitivity in Human Osteosarcoma.	ABCA1 ABCB1	4.71e-06	2	76	2	32155954
Pubmed	Genetic variability, haplotype structures, and ethnic diversity of hepatic transporters MDR3 (ABCB4) and bile salt export pump (ABCB11).	ABCB11 ABCB4	4.71e-06	2	76	2	16763017
Pubmed	Biliary secretion of alpha-tocopherol and the role of the mdr2 P-glycoprotein in rats and mice.	ABCB1 ABCB4	4.71e-06	2	76	2	9473291
Pubmed	The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues.	ABCB1 ABCB4	4.71e-06	2	76	2	2471060
Pubmed	Compensatory role of P-glycoproteins in knockout mice lacking the bile salt export pump.	ABCB11 ABCB1	4.71e-06	2	76	2	19650158
Pubmed	Sequence analysis of bile salt export pump (ABCB11) and multidrug resistance p-glycoprotein 3 (ABCB4, MDR3) in patients with intrahepatic cholestasis of pregnancy.	ABCB11 ABCB4	4.71e-06	2	76	2	15077010
Pubmed	MDR1 and MDR3 genes and drug resistance to cisplatin of ovarian cancer cells.	ABCB1 ABCB4	4.71e-06	2	76	2	18231753
Pubmed	ABC proteins protect the human body and maintain optimal health.	ABCA1 ABCB1	4.71e-06	2	76	2	21389634
Pubmed	ABCB4 and ABCB11 mutations in intrahepatic cholestasis of pregnancy in an Italian population.	ABCB11 ABCB4	4.71e-06	2	76	2	23022423
Pubmed	ABCB1/4 gallbladder cancer risk variants identified in India also show strong effects in Chileans.	ABCB1 ABCB4	4.71e-06	2	76	2	32058310
Pubmed	Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins.	ABCB1 ABCB4	4.71e-06	2	76	2	3768958
Pubmed	Role of ABCB1 and ABCB4 in renal and biliary excretion of perfluorooctanoic acid in mice.	ABCB1 ABCB4	4.71e-06	2	76	2	38522903
Pubmed	Localization of the human multiple drug resistance gene, MDR1, to 7q21.1.	ABCB1 ABCB4	4.71e-06	2	76	2	3477522
Pubmed	Clinical factors and ABCB1 polymorphisms in prediction of antiepileptic drug response: a prospective cohort study.	ABCB1 ABCB4	4.71e-06	2	76	2	16857572
Pubmed	ABCA1 Is Coordinated with ABCB1 in the Arsenic-Resistance of Human Cells.	ABCA1 ABCB1	4.71e-06	2	76	2	29951962
Pubmed	Physical mapping, amplification, and overexpression of the mouse mdr gene family in multidrug-resistant cells.	ABCB1 ABCB4	4.71e-06	2	76	2	1969609
Pubmed	Expression of MDR1 and MDR3 gene products in paclitaxel-, doxorubicin- and vincristine-resistant cell lines.	ABCB1 ABCB4	4.71e-06	2	76	2	24140176
Pubmed	Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis.	ABCB1 ABCB4	4.71e-06	2	76	2	9419367
Pubmed	Cell-specific activity of cis-acting regulatory elements in the promoter of the mouse multidrug resistance gene mdr1.	ABCB1 ABCB4	4.71e-06	2	76	2	2248681
Pubmed	Association of the ATP-binding cassette transporter A1 R230C variant with early-onset type 2 diabetes in a Mexican population.	ABCA1 ABCB1	4.71e-06	2	76	2	18003760
Pubmed	Interaction between SIDT2 and ABCA1 Variants with Nutrients on HDL-c Levels in Mexican Adults.	ABCA1 SIDT2	4.71e-06	2	76	2	36678241
Pubmed	The role of multiple drug resistance proteins in fetal and/or placental protection against teratogen-induced orofacial clefting.	ABCB1 ABCB4	4.71e-06	2	76	2	17440929
Pubmed	Amplification of the murine mdr2 gene and a reconsideration of the structure of the murine mdr gene locus.	ABCB1 ABCB4	4.71e-06	2	76	2	7832992
Pubmed	Common variants of ABCB4 and ABCB11 and plasma lipid levels: a study in sib pairs with gallstones, and controls.	ABCB11 ABCB4	4.71e-06	2	76	2	19408031
Pubmed	Mdr P-glycoproteins are not essential for biliary excretion of the hydrophobic heme precursor protoporphyrin in a griseofulvin-induced mouse model of erythropoietic protoporphyria.	ABCB1 ABCB4	4.71e-06	2	76	2	11826402
Pubmed	BSEP and MDR3 haplotype structure in healthy Caucasians, primary biliary cirrhosis and primary sclerosing cholangitis.	ABCB11 ABCB4	4.71e-06	2	76	2	14999697
Pubmed	A comprehensive analysis of common genetic variation around six candidate loci for intrahepatic cholestasis of pregnancy.	ABCB11 ABCB4	4.71e-06	2	76	2	24366234
Pubmed	mdr1a-encoded P-glycoprotein is not required for peripheral T cell proliferation, cytokine release, or cytotoxic effector function in mice.	ABCB1 ABCB4	4.71e-06	2	76	2	10453001
Pubmed	Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease.	ABCA1 ABCB11 ABCC6 ABCB4	8.75e-06	59	76	4	20855565
Pubmed	Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse.	ABCB1 ABCB4	1.41e-05	3	76	2	7814632
Pubmed	Heterozygous mutations of ATP8B1, ABCB11 and ABCB4 cause mild forms of Progressive Familial Intrahepatic Cholestasis in a pediatric cohort.	ABCB11 ABCB4	1.41e-05	3	76	2	34942279
Pubmed	Transbilayer movement of NBD-labeled phospholipids in red blood cell membranes: outward-directed transport by the multidrug resistance protein 1 (MRP1).	ABCB1 ABCB4	1.41e-05	3	76	2	9778357
Pubmed	Differences between nuclear run-off and mRNA levels for multidrug resistance gene expression in the cephalocaudal axis of the mouse intestine.	ABCB1 ABCB4	1.41e-05	3	76	2	8547326
Pubmed	Clinical phenotype of adult-onset liver disease in patients with variants in ABCB4, ABCB11, and ATP8B1.	ABCB11 ABCB4	1.41e-05	3	76	2	35894240
Pubmed	Human ABCB1 with an ABCB11-like degenerate nucleotide binding site maintains transport activity by avoiding nucleotide occlusion.	ABCB11 ABCB1	1.41e-05	3	76	2	33031417
Pubmed	Src-type tyrosine kinase p56lck is critical for thymic stromal lymphopoietin-induced allergic rhinitis.	LCK STAT6	1.41e-05	3	76	2	29752758
Pubmed	Hepatobiliary transporter expression and post-operative jaundice in patients undergoing partial hepatectomy.	ABCB11 ABCB4	1.41e-05	3	76	2	22098322
Pubmed	Structural and functional analysis of the apoptosis-associated tyrosine kinase (AATYK) family.	AATK LMTK3	1.41e-05	3	76	2	17651901
Pubmed	Immunolocalization of ABC drug transporters in human placenta from normal and gestational diabetic pregnancies.	ABCB1 ABCB4	1.41e-05	3	76	2	25029804
Pubmed	TLR2 mediates gap junctional intercellular communication through connexin-43 in intestinal epithelial barrier injury.	GJA1 ABCB1	1.41e-05	3	76	2	19528242
Pubmed	Selected ABCB1, ABCB4 and ABCC2 polymorphisms do not enhance the risk of drug-induced hepatotoxicity in a Spanish cohort.	ABCB1 ABCB4	1.41e-05	3	76	2	24732756
Pubmed	Association of ABCB1, ABCC5 and xanthine oxidase genetic polymorphisms with methotrexate adverse reactions in Mexican pediatric patients with ALL.	XDH ABCB1	1.41e-05	3	76	2	26353179
Pubmed	Function of prokaryotic and eukaryotic ABC proteins in lipid transport.	ABCA1 ABCB1	1.41e-05	3	76	2	15749056
Pubmed	Intracellular expression of P-170 glycoprotein in peripheral blood mononuclear cell subsets from healthy donors and HIV-infected patients.	ABCB1 ABCB4	1.41e-05	3	76	2	9542318
Pubmed	Identification of genetic variants in pharmacokinetic genes associated with Ewing Sarcoma treatment outcome.	ABCC6 ABCB1	1.41e-05	3	76	2	27287205
Pubmed	Role of common canalicular transporter gene variations in aetiology of idiopathic gallstones in childhood.	ABCB11 ABCB4	1.41e-05	3	76	2	20163776
Pubmed	Localization of the mouse Na+/H+ exchanger gene on distal chromosome 4.	SLC9A1 LCK	1.41e-05	3	76	2	8094369
Pubmed	Sequencing of FIC1, BSEP and MDR3 in a large cohort of patients with cholestasis revealed a high number of different genetic variants.	ABCB11 ABCB4	1.41e-05	3	76	2	28733223
Pubmed	Structural and functional characterization of the mouse multidrug resistance gene family.	ABCB1 ABCB4	1.41e-05	3	76	2	1980424
Pubmed	DHPLC screening for mutations in progressive familial intrahepatic cholestasis patients.	ABCB11 ABCB4	1.41e-05	3	76	2	20414253
Pubmed	ATP8B1, ABCB11, and ABCB4 Genes Defects: Novel Mutations Associated with Cholestasis with Different Phenotypes and Outcomes.	ABCB11 ABCB4	1.41e-05	3	76	2	33915153
Pubmed	Cryptogenic cholestasis in young and adults: ATP8B1, ABCB11, ABCB4, and TJP2 gene variants analysis by high-throughput sequencing.	ABCB11 ABCB4	2.82e-05	4	76	2	29238877
Pubmed	Association of polymorphisms of CYP2C9, CYP2C19, and ABCB1, and activity of P-glycoprotein with response to anti-epileptic drugs.	ABCA1 ABCB1	2.82e-05	4	76	2	25121365
Pubmed	Analysis of gene mutations in children with cholestasis of undefined etiology.	ABCB11 ABCB4	2.82e-05	4	76	2	20683201
Pubmed	A spectrum of ABCC6 mutations is responsible for pseudoxanthoma elasticum.	ABCC6 ABCB1	2.82e-05	4	76	2	11536079
Pubmed	Murine mdr-1, mdr-2, and mdr-3 gene expression: no coinduction with the Cyp1a-1 and Nmo-1 genes in liver by 2,3,7,8-tetrachlorodibenzo-p-dioxin.	ABCB1 ABCB4	2.82e-05	4	76	2	2069718
Pubmed	Familial intrahepatic cholestasis: New and wide perspectives.	ABCB11 ABCB4	2.82e-05	4	76	2	31105019
Pubmed	Hepatic lipase maturation: a partial proteome of interacting factors.	SLC25A3 HSP90B2P SLC25A5	4.31e-05	31	76	3	19136429
Pubmed	A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia.	RAPGEF4 TIAM2	4.69e-05	5	76	2	9789079
Pubmed	Application of high-resolution melting to large-scale, high-throughput SNP genotyping: a comparison with the TaqMan method.	NQO1 ABCB1	4.69e-05	5	76	2	20371868
Pubmed	Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population.	ABCB11 ABCB1	4.69e-05	5	76	2	11829140
Pubmed	Temporal/spatial expression and efflux activity of ABC transporter, P-glycoprotein/Abcb1 isoforms and Bcrp/Abcg2 during early murine development.	ABCB1 ABCB4	4.69e-05	5	76	2	16458078
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SLC25A3 ATP5MG GJA1 RAP1GDS1 HSP90B2P SLC25A5 EPB41L4B RAPGEF4 PSD3 SMU1 SSB PLEC	6.09e-05	1431	76	12	37142655
Pubmed	Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression.	ABCA1 STAT6	7.03e-05	6	76	2	30930171
Pubmed	Molecular alterations of the Fyn-complex occur as late events of human T cell activation.	FRK LCK	7.03e-05	6	76	2	10229084
Pubmed	Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways.	MUC4 STAT6	7.03e-05	6	76	2	12107190
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	SLC25A3 FRK KL RAP1GDS1 SLC12A1 SLC22A13 ABCB11 MBD5 TIAM2 ABCB1	7.22e-05	1016	76	10	19056867
Pubmed	Genetic susceptibility to febrile seizures: case-control association studies.	GJA1 SLC9A1	9.83e-05	7	76	2	19854014
Pubmed	Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis.	ABCA1 KL ABCB1	1.01e-04	41	76	3	19878569
Pubmed	Discovery and refinement of loci associated with lipid levels.	FRK ABCA1 FER1L4 ABCB11 PLEC	1.02e-04	211	76	5	24097068
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	HSP90B2P SLC25A5 XDH SSB EIF3B PLEC	1.09e-04	344	76	6	30333137
Interaction	CDC42 interactions	SLC25A3 TGFBR1 MAGI1 GJA1 ABCA1 SLC9A1 RAP1GDS1 EPB41L4B P4HA1 EXD2 TM9SF3 NQO1 PSD3 PLCB4 SSB ERGIC2 LCK SLC7A6	6.32e-07	1323	72	18	int:CDC42
Interaction	RHOA interactions	SLC25A3 TGFBR1 MAGI1 ATP5MG GJA1 SLC9A1 RAP1GDS1 SLC25A5 P4HA1 EXD2 TM9SF3 PLCB4 ERGIC2 MBD5 SLC7A6 CLEC16A	3.88e-06	1199	72	16	int:RHOA
Cytoband	7q21.12	ELAPOR2 ABCB1	7.52e-05	8	76	2	7q21.12
Cytoband	14q24.1	EXD2 GALNT16	1.55e-03	35	76	2	14q24.1
Cytoband	Ensembl 112 genes in cytogenetic band chr7q21	ELAPOR2 ABCB1 ABCB4	3.27e-03	178	76	3	chr7q21
Cytoband	Ensembl 112 genes in cytogenetic band chr2q31	RAPGEF4 ABCB11 SSB	3.27e-03	178	76	3	chr2q31
GeneFamily	ATP binding cassette subfamily B	ABCB11 ABCB1 ABCB4	4.32e-06	11	55	3	806
GeneFamily	Solute carriers	SLC25A3 SLC25A21 SLC9A1 SLC12A1 SLC25A5 SLC22A13 SLC7A6 SLC48A1	2.40e-05	395	55	8	752
GeneFamily	Type 1 receptor serine/threonine kinases	TGFBR1 ACVR1C	1.89e-04	7	55	2	345
GeneFamily	Polypeptide N-acetylgalactosaminyltransferases	GALNT17 GALNT16	1.67e-03	20	55	2	433
GeneFamily	SH2 domain containing	FRK LCK STAT6	3.60e-03	101	55	3	741
Coexpression	BLALOCK_ALZHEIMERS_DISEASE_DN	SLC25A3 ATP5MG KL RAP1GDS1 SLC25A5 P4HA1 RAPGEF4 NQO1 PSD3 SSB ERGIC2 SULT4A1 PHTF1 ABCB1	1.24e-05	1248	76	14	M17728
Coexpression	GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_1H_UP	PRSS54 GALNT17 BRS3 FER1L4 XDH GALNT16	1.51e-05	182	76	6	M4255
Coexpression	GSE17721_CTRL_VS_PAM3CSK4_24H_BMDC_DN	IVD FRK IER3IP1 DUSP2 NQO1 ABCB4	2.57e-05	200	76	6	M3752
Coexpression	GSE17721_ALL_VS_24H_PAM3CSK4_BMDC_DN	GJA1 FRK NQO1 PSD3 PLCB4 ABCB4	2.57e-05	200	76	6	M4116
Coexpression	BURTON_ADIPOGENESIS_2	GJA1 SIDT2 XDH SLC7A6	5.47e-05	71	76	4	M1582
Coexpression	BURTON_ADIPOGENESIS_2	GJA1 SIDT2 XDH SLC7A6	5.78e-05	72	76	4	MM673
Coexpression	BROWNE_HCMV_INFECTION_30MIN_DN	GJA1 SLC12A1 DUSP2 MMP3 MUC4	6.51e-05	145	76	5	M0
ToppCell	Control-Endothelial-VE_Peribronchial\|Control / Disease state, Lineage and Cell class	MAGI1 GJA1 ANO2 RAPGEF4 PLCB4 ABCB1	8.43e-07	188	76	6	f5b7dbc89f992c13280d36a34935be83906b1bc0
ToppCell	Control-Endothelial-VE_Peribronchial\|World / Disease state, Lineage and Cell class	MAGI1 GJA1 ANO2 RAPGEF4 PLCB4 ABCB1	8.69e-07	189	76	6	c76d8af2e0aa4a83ee0c3439c894566fbf117dd3
ToppCell	IPF-Endothelial-VE_Venous\|IPF / Disease state, Lineage and Cell class	MAGI1 GJA1 ANO2 RAPGEF4 PLCB4 ABCB1	9.82e-07	193	76	6	29a655fa80feaabe846c90a28363b037e22d24ae
ToppCell	IPF-Endothelial\|IPF / Disease state, Lineage and Cell class	MAGI1 GJA1 ANO2 RAPGEF4 PLCB4 ABCB1	1.01e-06	194	76	6	9591993aa2dcba3d09a0f1ea8b8f2439c26482d6
ToppCell	IPF-Endothelial-VE_Peribronchial\|World / Disease state, Lineage and Cell class	MAGI1 GJA1 ANO2 RAPGEF4 PLCB4 ABCB1	1.04e-06	195	76	6	120296531bbc8080dcabacbd64733cc1dc34603a
ToppCell	IPF-Endothelial-VE_Peribronchial\|IPF / Disease state, Lineage and Cell class	MAGI1 GJA1 ANO2 RAPGEF4 PLCB4 ABCB1	1.04e-06	195	76	6	2c3ad3cb79f11119ac69c413a938d21199145040
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC25A3 CPTP ATP5MG SLC12A1 SLC25A5 MRPL41	1.17e-06	199	76	6	41f3f5df41a142240947d9a57a6a282cba0c7aaa
ToppCell	facs-Liver-Hepatocytes-3m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPB41L4B RAPGEF4 ABCB11 GOLT1A ENTPD8	4.06e-06	139	76	5	82bf5ba69a907fbd9b4e2b2dd1dd27b8c4c75f25
ToppCell	facs-Liver-Hepatocytes-3m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPB41L4B RAPGEF4 ABCB11 GOLT1A ENTPD8	4.06e-06	139	76	5	fc9ac09c2106e88104a52575832d71d17765eec8
ToppCell	facs-Liver-Hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPB41L4B RAPGEF4 ABCB11 GOLT1A ENTPD8	4.06e-06	139	76	5	fc4b39ac9a10cf0acacfebbc4295edf324d930d5
ToppCell	facs-Liver-Hepatocytes-3m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPB41L4B RAPGEF4 ABCB11 GOLT1A ENTPD8	4.06e-06	139	76	5	4ddfbc36a0560fb70594627178bff652ab1ea3e9
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAPGEF4 ABCB11 ABCC6 ENTPD8 ABCB4	7.12e-06	156	76	5	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	ZMYND15 FRK FER1L4 TM9SF3 MUC4	7.81e-06	159	76	5	655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCell	facs-Marrow-KLS-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A21 NQO1 SLFN14 FAM187A ABCB4	8.55e-06	162	76	5	860ebf2390b4ad86475ad54717cbefcf61cd3b2a
ToppCell	facs-Marrow-KLS-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A21 NQO1 SLFN14 FAM187A ABCB4	8.55e-06	162	76	5	14e9f8aaba308619eb9da90796c336e76cedac1f
ToppCell	P07-Endothelial-lymphatic_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GJA1 DUSP2 NQO1 C3orf80 LCK	8.81e-06	163	76	5	5cbab3d03bb1af9391ecad635d6eea1dd42c1337
ToppCell	P07-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GJA1 DUSP2 NQO1 C3orf80 LCK	8.81e-06	163	76	5	322ba94c3ec1e1859c2e2195ecb3f7dab8d190f6
ToppCell	Endothelial-endothelial_cell_of_bronchial_vessel\|World / Lineage, Cell type, age group and donor	MAGI1 ANO2 RAPGEF4 PLCB4 ABCB1	9.35e-06	165	76	5	84e553d699ac56df89a77248f7308b9133e1b683
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ATP5MG SLC12A1 SLC25A5 MRPL41 GALNT16	1.05e-05	169	76	5	42c31fe94e34f54dbbb5d8b33cedb55badd6232c
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAGI1 ABCA1 C1QTNF9 ABCC6 ABCB4	1.31e-05	177	76	5	d68132e145bd413404fdbe215b5dbe520e756e50
ToppCell	droplet-Kidney-nan-21m-Epithelial-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A3 ATP5MG SLC12A1 SLC25A5 SLC22A13	1.42e-05	180	76	5	2b2c656d6620afa32555f14aad94ac56e71e360c
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANO2 RAPGEF4 C3orf80 PLCB4 ABCB1	1.42e-05	180	76	5	27e8bbee388e64dd79d70b160b76d45b1f398006
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CPTP ATP5MG SLC12A1 SLC25A5 MRPL41	1.42e-05	180	76	5	40f79b4455dbd1c2720dc32d9d77c70f835cecb3
ToppCell	Control-Endothelial_cells-Pulmonary_venous_endothelial_cells\|Control / group, cell type (main and fine annotations)	ANO2 RAPGEF4 PLCB4 SLC48A1 ABCB1	1.54e-05	183	76	5	46be9f96755c7b65aeac061d95d15abeb6466034
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT17 AATK SLC25A5 MRGPRF ABCB11	1.54e-05	183	76	5	f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	MAGI1 ANO2 RAPGEF4 PLCB4 ABCB1	1.62e-05	185	76	5	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	COPD-Endothelial-VE_Peribronchial\|COPD / Disease state, Lineage and Cell class	MAGI1 GJA1 ANO2 RAPGEF4 PLCB4	1.67e-05	186	76	5	23c7d0e8372a71546d687278b985f761d282f92f
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	MAGI1 ANO2 RAPGEF4 PLCB4 ABCB1	1.71e-05	187	76	5	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	droplet-Spleen-nan-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TLCD3B SLC25A21 FER1L4 NQO1 ABCB4	1.71e-05	187	76	5	c81d11d9fdc22dc39222f62c2888025c2e8c3e65
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 ANO2 RAPGEF4 PLCB4 ABCB1	1.75e-05	188	76	5	117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCell	COVID-19-lung-Vein_EC\|lung / Disease (COVID-19 only), tissue and cell type	MAGI1 ANO2 RAPGEF4 PLCB4 ABCB1	1.75e-05	188	76	5	d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell	droplet-Kidney-nan-3m-Epithelial-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A3 ATP5MG KL SLC12A1 SLC25A5	1.75e-05	188	76	5	6b185d0aaeea64f9ae584a9bcb9741658bb1c7bd
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAGI1 GJA1 ABCA1 NQO1 C3orf80	1.85e-05	190	76	5	e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAGI1 GJA1 ABCA1 NQO1 C3orf80	1.85e-05	190	76	5	f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCell	facs-Heart-RV-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 GJA1 C1QTNF9 XDH PLCB4	1.85e-05	190	76	5	89d1d686cc683206534e2157554d7d0df5d53497
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAGI1 GJA1 ABCA1 NQO1 C3orf80	1.85e-05	190	76	5	b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCell	facs-Heart-RV-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 GJA1 C1QTNF9 XDH PLCB4	1.85e-05	190	76	5	65ba6c4f4a2905c0bf4ff99518ae49e3dfd5e640
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAGI1 GJA1 ABCA1 NQO1 C3orf80	1.85e-05	190	76	5	a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAGI1 GJA1 ABCA1 NQO1 C3orf80	1.85e-05	190	76	5	0bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCell	COVID-19-Endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	MAGI1 ANO2 RAPGEF4 PLCB4 ABCB1	1.85e-05	190	76	5	9fbd92cd6d4683b2490504d29c43cf42020433d4
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAGI1 GJA1 ABCA1 NQO1 C3orf80	1.85e-05	190	76	5	26e2237f65cb43723c5da853831b40df2982d6e4
ToppCell	facs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 GJA1 ABCA1 NQO1 C3orf80	1.89e-05	191	76	5	48823a97c38263f2c6e58348214f5b62773a6368
ToppCell	Control-Endothelial-VE_Venous\|Control / Disease state, Lineage and Cell class	MAGI1 GJA1 ANO2 RAPGEF4 PLCB4	1.89e-05	191	76	5	617546cf4883dedf3323e03a53ba5adec334cf8e
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 GJA1 ABCA1 NQO1 C3orf80	1.89e-05	191	76	5	0eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 RAPGEF4 C1QTNF9 XDH PLCB4	1.94e-05	192	76	5	8f20d3511dcb44445592b17d005a53da0052ae56
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-SVEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GJA1 ANO2 RAPGEF4 PLCB4 ABCB1	1.94e-05	192	76	5	c3dda7c48732b0b8bde36de282d64192f5e9b98f
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial-endothelial_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 RAPGEF4 C1QTNF9 XDH PLCB4	1.94e-05	192	76	5	0986b7900021efe2a4df84a935e7c9a0af1b0e57
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 RAPGEF4 C1QTNF9 XDH PLCB4	1.94e-05	192	76	5	b28d294e42b303d1db6060231d84d7b9e4d9fccf
ToppCell	COPD-Endothelial\|COPD / Disease state, Lineage and Cell class	MAGI1 GJA1 ANO2 RAPGEF4 PLCB4	1.99e-05	193	76	5	093b28dcccb5841c995d0b33fae0efd6b88f97e0
ToppCell	IPF-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	MAGI1 GJA1 ANO2 RAPGEF4 PLCB4	1.99e-05	193	76	5	ef66a46e7ab44fcc4005a23416e6da478a4cce37
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)\|356C / Donor, Lineage, Cell class and subclass (all cells)	GJA1 ANO2 KL RAPGEF4 C1QTNF9	2.04e-05	194	76	5	2e5b195e02dcd5e9432b9a98b22e0478e65b9ba2
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 ANO2 RAPGEF4 PLCB4 ABCB1	2.04e-05	194	76	5	71ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	GJA1 ANO2 KL RAPGEF4 C1QTNF9	2.04e-05	194	76	5	b6b5b0ab506b05a005ba8a05a3c7f4c725ba9200
ToppCell	Control-Endothelial\|Control / Disease state, Lineage and Cell class	MAGI1 GJA1 ANO2 RAPGEF4 PLCB4	2.04e-05	194	76	5	485fe5538fabec457b9a51feb641f2a91cbf4e18
ToppCell	Control-Endothelial-VE_Arterial\|Control / Disease state, Lineage and Cell class	MAGI1 GJA1 ANO2 RAPGEF4 PLCB4	2.09e-05	195	76	5	56c66a3655820961e1390b8f4bcc5618e8d0c5a8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC25A3 ATP5MG SLC12A1 SLC25A5 MRPL41	2.14e-05	196	76	5	6cfb45827e70a65d6a81a7bcb305b2dafbbf641f
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 ABCA1 SIDT2 TM9SF3 XDH	2.14e-05	196	76	5	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA1 ABCA1 SIDT2 TM9SF3 XDH	2.14e-05	196	76	5	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GDPD5 ANO2 RAPGEF4 PLCB4 ABCB1	2.20e-05	197	76	5	b2b7f8dc8ca421441e4c99c4f5d18fbc1668d79f
ToppCell	distal-Endothelial-Bronchial_Vessel_1-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MAGI1 GJA1 RAPGEF4 C1QTNF9 ABCB1	2.20e-05	197	76	5	0d1afd1ad7489c071db08b3dfff598423097d7e0
ToppCell	distal-3-Endothelial-Bronchial_Vessel_2\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MAGI1 GJA1 RAPGEF4 C1QTNF9 PLCB4	2.25e-05	198	76	5	f701d06e3d7fd2192afae3698c5ec3c355e96da3
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC25A3 ATP5MG SLC12A1 SLC25A5 MRPL41	2.25e-05	198	76	5	64d73804902a043bdf66b413b769e853d111c033
ToppCell	distal-1-Endothelial-Bronchial_Vessel_1\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MAGI1 GJA1 RAPGEF4 C1QTNF9 ABCB1	2.25e-05	198	76	5	5cd81fe1a21c0e1a7f0d5a62ddf8e422b05aedc7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC25A3 ATP5MG SLC12A1 SLC25A5 MRPL41	2.25e-05	198	76	5	8777117249077d4964dd7566aebde7c443475c7e
ToppCell	(07)_Ionocytes\|World / shred by cell type by condition	SLC25A5 EPB41L4B PSD3 PLCB4 TIAM2	2.30e-05	199	76	5	8194777d367405a7840787e977854b5c07e3bd6b
ToppCell	kidney_cells-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC25A3 ATP5MG SLC25A5 MRPL41 FKBP2	2.36e-05	200	76	5	874ae350634936c7efd8b44895d20935a1747acd
ToppCell	E18.5-samps-Epithelial-Alveolar_epithelial-AT2_progenitor\|E18.5-samps / Age Group, Lineage, Cell class and subclass	SLC9A1 MTBP SLFN14 GOLT1A	6.24e-05	125	76	4	b5fed0e0295aa8ad323c318b59bf23cde3e758c8
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-ILC\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC25A5 IER3IP1 MMP3 ABCB1	6.44e-05	126	76	4	e33957cf1541733b06de9f9e7b2801b3d8ae831d
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-cortical_neurons_1\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	EPB41L4B BRS3 SULT4A1 ABCB1	9.95e-05	141	76	4	73b3e967357cba7585d97ec9e9d48d3e94ebe31e
ToppCell	367C-Epithelial_cells-Epithelial-D_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	GDPD5 ELAPOR2 ALS2 ACVR1C	9.95e-05	141	76	4	f3b1d757c4cac8596c542959c8f27f8bcaf3f513
ToppCell	367C-Epithelial_cells-Epithelial-D_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	GDPD5 ELAPOR2 ALS2 ACVR1C	9.95e-05	141	76	4	bf68a54e755cda89fbc416636e522cd71d1e42d0
ToppCell	E18.5-samps-Epithelial-Alveolar_epithelial-AT1_-_meso\|E18.5-samps / Age Group, Lineage, Cell class and subclass	KL EPB41L4B LMTK3 SULT4A1	1.02e-04	142	76	4	77fd145c1c500d580f70ac4e54c3fd879ecf0ab3
ToppCell	Enthrocyte\|World / shred on cell class and cell subclass (v4)	SLFN14 SLC48A1 ENTPD8 ABCB4	1.36e-04	153	76	4	654265f3c14344071b2af7ca05cbdbb17ce2c5d3
ToppCell	Enthrocyte\|World / shred on cell class and cell subclass (v4)	SLFN14 SLC48A1 ENTPD8 ABCB4	1.36e-04	153	76	4	105b91f5277d145f7717307d7eb9b7d8e8e23576
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 FRK GALNT17 PSD3	1.36e-04	153	76	4	0a4fbe46125b05ee235deb528855808c2bf33cba
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Pcdh11x_(Neuron.Gad1Gad2.Synpr-Pcdh11x)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	PRSS54 BRS3 SLFN14	1.41e-04	59	76	3	439a9d56eeecccd70a4defb430e228329655cb80
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Pcdh11x_(Neuron.Gad1Gad2.Synpr-Pcdh11x)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	PRSS54 BRS3 SLFN14	1.41e-04	59	76	3	50432c7b52fd197e8856ba0296c34cf66a2faaf5
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANO2 KL RAPGEF4 ABCB1	1.47e-04	156	76	4	ff39712c7a2dc1b85c598d5105789aa291dea726
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	KL MRGPRF NQO1 ABCB11	1.58e-04	159	76	4	cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DUSP2 LCK LMTK3 PHTF1	1.70e-04	162	76	4	0321fc954ae4ad67ca438cbbc84632562d222188
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DUSP2 LCK LMTK3 PHTF1	1.70e-04	162	76	4	5731f9514434296132df4bc86f78ce87b07cdeca
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA1 TLCD3B DUSP2 C3orf80	1.70e-04	162	76	4	96c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANO2 RAPGEF4 PLCB4 ABCB1	1.74e-04	163	76	4	977a970b1296234c22178420294cea73506ee02f
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANO2 RAPGEF4 PLCB4 ABCB1	1.74e-04	163	76	4	ba7d02db0f0e2f9916ec8db52c067c87b6917c23
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZMYND15 SLC25A21 SLC12A1 SLC48A1	1.78e-04	164	76	4	f3772227f5aa75a3672d945f8d5bf3fa0b4e456b
ToppCell	facs-Marrow-B-cells-24m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A21 ABCB11 SLFN14 ABCB4	1.78e-04	164	76	4	18eeda51e69722992c3a7f699be293535a90868b
ToppCell	droplet-Fat-Gat-18m-Hematologic\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A21 SLFN14 SLC48A1 ABCB4	1.78e-04	164	76	4	7dbe34a98a3b475c1ba678db8a5494c0c6a91e2d
ToppCell	droplet-Fat-Gat-18m-Hematologic-erythroblast\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A21 SLFN14 SLC48A1 ABCB4	1.78e-04	164	76	4	febcb8f8b305aa94e21131fa83d2890f7a6838fc
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCA1 DUSP2 NQO1 C3orf80	1.82e-04	165	76	4	347b59aa625a8a960828b8620824d8ac48990e07
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCA1 DUSP2 NQO1 C3orf80	1.82e-04	165	76	4	507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCA1 DUSP2 NQO1 C3orf80	1.82e-04	165	76	4	39a25be081a5d59c7cf107a997d352793d5025fb
ToppCell	droplet-Fat-Gat-18m-Hematologic-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC25A21 SLFN14 SLC48A1 ABCB4	1.82e-04	165	76	4	1e89154114327650df39befb2c56d0379ea6a221
ToppCell	PND03-Endothelial-Endothelial_lymphatic\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCA1 DUSP2 NQO1 C3orf80	1.82e-04	165	76	4	1890f9c33b0c5b381d57f97042da2610a093a6de
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANO2 RAPGEF4 PLCB4 ABCB1	1.91e-04	167	76	4	d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GALNT17 PSD3 ACVR1C GALNT16	1.95e-04	168	76	4	6db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANO2 RAPGEF4 ABCB1 ABCB4	2.00e-04	169	76	4	0d8b681404e18f3061d84425fb5f7d84e8e2b8d7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 GALNT17 PSD3 MUC4	2.00e-04	169	76	4	2a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCell	PND01-03-samps-Mesenchymal-Pericyte-pericyte_F\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	C1QTNF9 SLC7A6 GALNT16 ABCB4	2.04e-04	170	76	4	71718dcebd48105994c313bb55babc70301170a0
ToppCell	356C-Myeloid-Dendritic-cDC_activated\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	GJA1 FRK PSD3 TIAM2	2.04e-04	170	76	4	513d9036aa41d4d902da8baa66a66206abb6f3b0
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_dendritic-mature_conventional_dendritic_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GJA1 FRK RAPGEF4 GALNT16	2.09e-04	171	76	4	d934d68efc5739483c735dc702ccd30b07a6aa7e
Drug	Soybean Oil	ABCB11 ABCC6 ABCB1 ABCB4	5.33e-07	20	76	4	ctd:D013024
Drug	Nitrofurantoin	NQO1 ABCB11 XDH ABCB4	1.16e-06	24	76	4	ctd:D009582
Drug	Doxycycline	GJA1 ABCB11 MMP3 ABCB1 ABCB4	1.72e-06	60	76	5	ctd:D004318
Drug	senkirkine	RAPGEF4 NQO1 ABCB11 XDH ABCC6	1.86e-06	61	76	5	ctd:C009238
Drug	calcein AM	ABCB11 ABCC6 ABCB1	1.98e-06	8	76	3	ctd:C085925
Drug	T beta-MC	ABCB11 ABCB1 ABCB4	1.98e-06	8	76	3	CID000168408
Drug	Methamphetamine	IVD CPTP TGFBR1 MAGI1 TLCD3B SIDT2 P4HA1 SLC22A13 NQO1 PSD3 XDH MRPL41 PLEC LMTK3 ABCC6 STAT6 ABCB1	2.81e-06	1401	76	17	ctd:D008694
Drug	pregnenolone-16 alpha-carbonitrile	NQO1 ABCB11 PLEC ABCB1 ABCB4	2.98e-06	67	76	5	CID000015032
Drug	Pravastatin	ABCA1 ABCB11 MMP3 ABCB1 ABCB4	2.98e-06	67	76	5	ctd:D017035
Drug	Itraconazole	NQO1 ABCB11 ABCB1 ABCB4	3.84e-06	32	76	4	ctd:D017964
Drug	rhodamine 123	NQO1 ABCB11 ABCC6 ABCB1 ABCB4	3.98e-06	71	76	5	CID000065217
Drug	Cholic Acid	ABCA1 NQO1 ABCB11 ABCB1 ABCB4	5.22e-06	75	76	5	ctd:D019826
Drug	phenylalanine	HIPK3 SLC25A3 PLCB4 MMP3 SLC7A6 SULT4A1 PHTF1	6.15e-06	208	76	7	CID000000994
Drug	benzbromarone	XDH ABCC6 ABCB1 ABCB4	6.96e-06	37	76	4	CID000002333
Drug	IC-1	SSB ABCB1 ABCB4	7.69e-06	12	76	3	CID000049829
Drug	CaLam	ABCB11 ABCC6 ABCB1 ABCB4	8.63e-06	39	76	4	CID004126474
Drug	Phalloidine	NQO1 ABCB11 ABCB1	9.98e-06	13	76	3	ctd:D010590
Drug	antofine	GJA1 ABCB1	1.10e-05	2	76	2	ctd:C473343
Drug	tasosartan	ABCB11 ABCB4	1.10e-05	2	76	2	ctd:C086167
Drug	1,9-dideoxyforskolin	ABCB1 ABCB4	1.10e-05	2	76	2	ctd:C047983
Drug	benziodarone	ABCB11 ABCB4	1.10e-05	2	76	2	ctd:C058702
Drug	tipranavir	ABCB11 ABCB4	1.10e-05	2	76	2	ctd:C107201
Drug	estradiol-3-glucuronide	KL ABCB11	1.10e-05	2	76	2	ctd:C025482
Drug	AC1Q6PCP	SLC9A1 SLC12A1 MMP3 PLEC ABCC6 ABCB1 ABCB4	1.19e-05	230	76	7	CID000005267
Drug	cyclophorine	GJA1 KL SLC25A5 ABCB11 SULT4A1 FKBP2 ABCC6 ABCB1 ABCB4	1.22e-05	426	76	9	CID000002909
Drug	robinetin	SLC25A21 ABCB1 ABCB4	1.27e-05	14	76	3	CID005281692
Drug	NSC648766	SLC12A1 ABCB11 PLEC ABCB1 ABCB4	1.50e-05	93	76	5	CID000003199
Drug	Lithocholic Acid	TGFBR1 ABCA1 NQO1 ABCB11 ABCC6 ABCB1 ABCB4	1.56e-05	240	76	7	ctd:D008095
Drug	lapatinib	NQO1 ABCB11 ABCB1 ABCB4	1.83e-05	47	76	4	ctd:C490728
Drug	GW3965	ABCB11 PLEC ABCB1 ABCB4	1.83e-05	47	76	4	CID000447905
Drug	AC1NQGK1	KL NQO1 ABCC6 ABCB4	2.75e-05	52	76	4	CID005195977
Drug	adrenochrome	IVD NQO1 XDH	2.81e-05	18	76	3	CID000005898
Drug	Fluvoxamine	ABCB11 ABCB1 ABCB4	2.81e-05	18	76	3	ctd:D016666
Drug	Flavin-Adenine Dinucleotide	IVD NQO1 XDH	2.81e-05	18	76	3	DB03147
Drug	Technetium Tc 99m Sestamibi	ABCB1 ABCB4	3.29e-05	3	76	2	ctd:D017256
Drug	efonidipine	ABCA1 ABCB1	3.29e-05	3	76	2	ctd:C066425
Drug	Elacridar	ABCB11 ABCB1	3.29e-05	3	76	2	ctd:C083501
Drug	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	ABCB11 ABCB1	3.29e-05	3	76	2	ctd:C541506
Drug	Apa-sg	NQO1 ABCC6 ABCB1	3.33e-05	19	76	3	CID000126348
Drug	AC1L3C9O	GJA1 ABCB11 ABCC6 ABCB1 ABCB4	3.38e-05	110	76	5	CID000002521
Drug	oltipraz	NQO1 ABCB11 ABCC6 ABCB1	3.69e-05	56	76	4	ctd:C026209
Drug	Carboplatin	NQO1 XDH ACVR1C STAT6 ABCB4	3.84e-05	113	76	5	ctd:D016190
Drug	Streptozocin	SLC25A3 TGFBR1 KL SLC25A5 NQO1 ABCB11 XDH MMP3 ABCC6 ABCB1 ABCB4	4.03e-05	756	76	11	ctd:D013311
Drug	ciprofibrate	AIG1 NQO1 ABCB11 ABCB1 ABCB4	4.18e-05	115	76	5	ctd:C019304
Drug	3-isoreserpine	ABCA1 NQO1 ABCB11 ABCC6 ABCB1 ABCB4	4.20e-05	190	76	6	CID000005052
Drug	5 beta-pregnanediol	ABCA1 ABCB11 FKBP2 ABCB1	4.85e-05	60	76	4	CID000012547
Drug	Tremorine dihydrochloride [300-68-5]; Up 200; 15uM; MCF7; HT_HG-U133A	HIPK3 GDPD5 FRK XDH PLEC SLC48A1	5.00e-05	196	76	6	6273_UP
Drug	phorbol acetate myristate	GJA1 SLC25A21 SLC9A1 KL SLC12A1 BRS3 DUSP2 XDH PLCB4 MMP3 LCK MUC4 PHTF1 ABCB1 ABCB4	5.08e-05	1399	76	15	CID000004792
Drug	6-methylpurine-2'-deoxyriboside	ABCB11 ABCC6 ABCB1 ABCB4	5.18e-05	61	76	4	CID000097184
Drug	NSC119914	ABCB11 PLEC ABCB1	5.26e-05	22	76	3	CID000274126
Drug	estradiol-17 beta-glucuronide	ABCB11 ABCB1 ABCB4	5.26e-05	22	76	3	ctd:C025483
Drug	pitavastatin	ABCA1 ABCB11 ABCB1	5.26e-05	22	76	3	ctd:C108475
Drug	Calcein AM	GJA1 ABCC6 ABCB1 ABCB4	5.52e-05	62	76	4	CID000390986
Drug	3-OHBaP	KL NQO1 XDH SULT4A1	5.88e-05	63	76	4	CID000025890
Drug	hydroxyrubicin	XDH ABCC6 ABCB1	6.03e-05	23	76	3	CID000072398
Drug	dimethylaminobenzoate	ABCB1 ABCB4	6.57e-05	4	76	2	CID012241998
Drug	phosphorus pentoxide	ANO2 XDH	6.57e-05	4	76	2	CID000014812
Drug	fipexide	ABCB11 ABCB4	6.57e-05	4	76	2	ctd:C038628
Drug	fluorexon	ABCC6 ABCB1	6.57e-05	4	76	2	ctd:C007740
Drug	8-azidoadenosine 5'-triphosphate	ABCC6 ABCB1	6.57e-05	4	76	2	ctd:C017040
Drug	2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)acetamide	ABCB11 ABCB1	6.57e-05	4	76	2	ctd:C521104
Drug	FK317	NQO1 ABCB1	6.57e-05	4	76	2	CID000190373
Drug	AC1L85AO	ABCB11 ABCC6 ABCB1 ABCB4	7.06e-05	66	76	4	CID000372705
Drug	nsc25485	SLC25A3 SLC9A1 SLC12A1 PLCB4 LCK PHTF1 ABCB1	8.26e-05	312	76	7	CID000004605
Drug	DMEs	NQO1 PLEC SULT4A1 ABCB1	9.40e-05	71	76	4	CID003038361
Drug	oltipraz	NQO1 ABCB11 PLEC ABCC6 ABCB4	9.61e-05	137	76	5	CID000047318
Drug	AC1L1TSE	ABCB11 ABCC6 ABCB1 ABCB4	9.93e-05	72	76	4	CID000060719
Drug	BCECF	SLC25A3 SLC9A1 ABCC6 ABCB1	1.05e-04	73	76	4	CID004241719
Drug	GDP-Ara	SULT4A1 ABCC6	1.09e-04	5	76	2	CID003036025
Drug	PAME	SLC25A3 ABCB11	1.09e-04	5	76	2	CID000152956
Drug	L-754,394	KL ABCB1	1.09e-04	5	76	2	CID005481990
Drug	sakuranin	XDH ABCB1	1.09e-04	5	76	2	CID000073607
Drug	epiallopregnanolone sulfate	ABCB11 ABCB4	1.09e-04	5	76	2	ctd:C579439
Drug	AC1L2MCS	ABCB1 ABCB4	1.09e-04	5	76	2	CID000023441
Drug	Texas Red	GJA1 ABCC6 ABCB1	1.10e-04	28	76	3	CID000452705
Drug	senecionine	RAPGEF4 NQO1 ABCB11 ABCC6	1.10e-04	74	76	4	ctd:C009237
Drug	oxidized glutathione	NQO1 XDH MMP3 ABCC6 ABCB1 ABCB4	1.12e-04	227	76	6	CID000000975
Drug	troglitazone	HIPK3 FRK ABCA1 SLC9A1 KL AATK SLC12A1 ABCB11 PLEC SLC7A6 GALNT16 ABCC6 ABCB1 ABCB4	1.13e-04	1329	76	14	ctd:C057693
Drug	valdecoxib	IVD ASNSD1 GJA1 P4HA1 RAPGEF4 AIG1 NQO1 PHTF1 ABCB1 ABCB4	1.15e-04	705	76	10	ctd:C406224
Drug	3 alpha,6 alpha-dihydroxy-5 beta-cholanoic acid	PLEC ABCB1 ABCB4	1.23e-04	29	76	3	CID000006747
Drug	2,8-dihydroxyadenine	SLC12A1 NQO1 XDH	1.23e-04	29	76	3	CID000092268
Drug	Loratadine	ABCB11 ABCB1 ABCB4	1.36e-04	30	76	3	ctd:D017336
Drug	davidigenin	ABCB11 ABCB1 ABCB4	1.36e-04	30	76	3	CID000442342
Drug	AC1L9E0Q	ABCC6 ABCB1 ABCB4	1.36e-04	30	76	3	CID000443095
Drug	AC1L1J6H	GJA1 ABCB11 MMP3 ABCC6 ABCB1 ABCB4	1.39e-04	236	76	6	CID000004889
Drug	Clofibric Acid	SIDT2 SLC25A5 RAPGEF4 ABCB11 XDH SSB EIF3B ABCC6 ABCB1 ABCB4	1.48e-04	727	76	10	ctd:D002995
Drug	NSC332598	ABCA1 NQO1 ABCB1	1.50e-04	31	76	3	CID000615942
Drug	bisbenzimide ethoxide trihydrochloride	ABCB11 ABCB1	1.64e-04	6	76	2	ctd:C017807
Drug	PIHCA	ABCB1 ABCB4	1.64e-04	6	76	2	CID000108097
Drug	AC1L99H3	ABCB1 ABCB4	1.64e-04	6	76	2	CID000440540
Drug	v 104	ABCB1 ABCB4	1.64e-04	6	76	2	CID000107262
Drug	Brilliant Blue R	SLC12A1 XDH	1.64e-04	6	76	2	CID000061365
Drug	H0336	SLC25A21 NQO1	1.64e-04	6	76	2	CID000011600
Drug	17beta-estradiol glucuronide	ABCB11 ABCC6 ABCB1	1.65e-04	32	76	3	CID000066424
Drug	18b-glycyrrhetic acid	GJA1 SLC25A21 KL STAT6	1.73e-04	83	76	4	CID000003230
Drug	NSC 117356	SLC22A13 XDH MMP3 ABCC6 ABCB1 ABCB4	1.74e-04	246	76	6	CID000004112
Drug	Adenosine triphosphate	ABCA1 ABCB11 ABCB1	1.81e-04	33	76	3	DB00171
Drug	N-methylnicotinamide	NQO1 XDH ABCB1	1.99e-04	34	76	3	CID000064950
Drug	AC1LCF1F	KL ABCB11 ABCC6 ABCB1 ABCB4	2.05e-04	161	76	5	CID000627275
Drug	AC-759	ABCB11 ABCC6 ABCB1 ABCB4	2.16e-04	88	76	4	CID000005396
Disease	cholestasis (biomarker_via_orthology)	NQO1 ABCB11 XDH ABCB1 ABCB4	1.32e-07	49	72	5	DOID:13580 (biomarker_via_orthology)
Disease	cystic fibrosis (implicated_via_orthology)	ABCB11 ABCB1 ABCB4	1.16e-06	9	72	3	DOID:1485 (implicated_via_orthology)
Disease	Colorectal Neoplasms	TGFBR1 ABCA1 NQO1 ABCB11 ABCC6 ABCB1 ABCB4	5.21e-06	277	72	7	C0009404
Disease	human immunodeficiency virus infectious disease (implicated_via_orthology)	LCK ABCB1	5.87e-06	2	72	2	DOID:526 (implicated_via_orthology)
Disease	aspartate aminotransferase measurement	SLC25A3 MAGI1 FRK ABCA1 ABCB11 XDH SLC48A1 GOLT1A CLEC16A ABCB1 ABCB4	1.15e-05	904	72	11	EFO_0004736
Disease	polypeptide N-acetylgalactosaminyltransferase 16 measurement	GALNT17 GALNT16	1.76e-05	3	72	2	EFO_0801900
Disease	Progressive intrahepatic cholestasis (disorder)	ABCB11 ABCB4	1.76e-05	3	72	2	C0268312
Disease	Progressive familial intrahepatic cholestasis type 3	ABCB11 ABCB4	1.76e-05	3	72	2	cv:C1865643
Disease	Cholestasis, benign recurrent intrahepatic 1	ABCB11 ABCB4	1.76e-05	3	72	2	C4551899
Disease	polyunsaturated fatty acid measurement	FRK ABCA1 FER1L4 PSD3 ABCB11	1.76e-05	131	72	5	EFO_0010733
Disease	apolipoprotein B measurement	FRK SIDT2 FER1L4 PSD3 ABCB11 PLEC ACVR1C ABCB1 ABCB4	3.33e-05	663	72	9	EFO_0004615
Disease	intrahepatic cholestasis (is_implicated_in)	ABCB11 ABCB4	3.51e-05	4	72	2	DOID:1852 (is_implicated_in)
Disease	overactive bladder syndrome (biomarker_via_orthology)	GJA1 NQO1	3.51e-05	4	72	2	DOID:0070355 (biomarker_via_orthology)
Disease	Glycochenodeoxycholic acid measurement	GALNT17 GALNT16	3.51e-05	4	72	2	EFO_0021599
Disease	Cholestasis, progressive familial intrahepatic 1	ABCB11 ABCB4	3.51e-05	4	72	2	C4551898
Disease	Disease Exacerbation	GJA1 FKBP2 ABCC6 ABCB1 ABCB4	5.32e-05	165	72	5	C0235874
Disease	low density lipoprotein cholesterol measurement, alcohol consumption measurement	FRK ABCA1 PSD3 ABCB11	1.03e-04	99	72	4	EFO_0004611, EFO_0007878
Disease	coronary artery disease (is_implicated_in)	ABCA1 KL MMP3 ABCC6	1.07e-04	100	72	4	DOID:3393 (is_implicated_in)
Disease	low density lipoprotein cholesterol measurement, alcohol drinking	FRK ABCA1 PSD3 ABCB11	1.16e-04	102	72	4	EFO_0004329, EFO_0004611
Disease	omega-6 polyunsaturated fatty acid measurement	FRK ABCA1 FER1L4 PSD3 ABCB11	1.23e-04	197	72	5	EFO_0005680
Disease	Cholestasis of pregnancy	ABCB11 ABCB4	1.63e-04	8	72	2	C0268318
Disease	gallbladder neoplasm	ABCB1 ABCB4	2.09e-04	9	72	2	EFO_0004606
Disease	cholestasis (implicated_via_orthology)	ABCB11 ABCB4	2.09e-04	9	72	2	DOID:13580 (implicated_via_orthology)
Disease	phosphatidylethanolamine ether measurement	GALNT17 GALNT16	2.61e-04	10	72	2	EFO_0010229
Disease	aspartate aminotransferase to alanine aminotransferase ratio	ABCB11 PLEC GOLT1A ABCB1 ABCB4	3.01e-04	239	72	5	EFO_0010934
Disease	Colorectal Carcinoma	TGFBR1 ABCA1 KL NQO1 ABCB11 ABCC6 ABCB1 ABCB4	3.09e-04	702	72	8	C0009402
Disease	Peripheral Nervous System Diseases	ABCA1 MMP3 ABCB1	3.16e-04	54	72	3	C4721453
Disease	urate measurement	FRK ABCA1 HSP90B2P SLC12A1 PSD3 SMU1 XDH MBD5 SLC48A1	3.21e-04	895	72	9	EFO_0004531
Disease	chronic kidney disease (implicated_via_orthology)	NQO1 XDH	3.81e-04	12	72	2	DOID:784 (implicated_via_orthology)
Disease	respiratory system disease	TGFBR1 GJA1 CLEC16A STAT6	4.44e-04	145	72	4	EFO_0000684
Disease	type 2 diabetes mellitus (biomarker_via_orthology)	GJA1 SLC9A1 KL MMP3	4.68e-04	147	72	4	DOID:9352 (biomarker_via_orthology)
Disease	Intrahepatic cholestasis of pregnancy	ABCB1 ABCB4	6.89e-04	16	72	2	EFO_0009048
Disease	triglyceride measurement, low density lipoprotein cholesterol measurement	ZMYND15 ABCA1 PSD3 ABCB11	7.38e-04	166	72	4	EFO_0004530, EFO_0004611
Disease	renal fibrosis (implicated_via_orthology)	XDH STAT6	7.80e-04	17	72	2	DOID:0050855 (implicated_via_orthology)
Disease	renovascular hypertension (biomarker_via_orthology)	GJA1 SLC9A1	9.77e-04	19	72	2	DOID:1591 (biomarker_via_orthology)
Disease	HMG CoA reductase inhibitor use measurement	ABCA1 NQO1 PSD3 PLEC	1.19e-03	189	72	4	EFO_0009932
Disease	chronic myeloid leukemia (is_implicated_in)	NQO1 ABCB1	1.20e-03	21	72	2	DOID:8552 (is_implicated_in)
Disease	peripheral arterial disease, traffic air pollution measurement	ABCA1 EPB41L4B MBD5 GOLT1A	1.31e-03	194	72	4	EFO_0004265, EFO_0007908
Disease	visual epilepsy (biomarker_via_orthology)	GJA1 NQO1 ABCB1	1.41e-03	90	72	3	DOID:11832 (biomarker_via_orthology)
Disease	non-high density lipoprotein cholesterol measurement	FRK ABCA1 PSD3 ABCB11 ERGIC2 ACVR1C ABCB4	1.77e-03	713	72	7	EFO_0005689
Disease	Edema	SLC9A1 STAT6	1.84e-03	26	72	2	C0013604
Disease	Anasarca	SLC9A1 STAT6	1.84e-03	26	72	2	C0151603
Disease	retinal degeneration (biomarker_via_orthology)	LCK ACVR1C	2.13e-03	28	72	2	DOID:8466 (biomarker_via_orthology)
Disease	corpus callosum central volume measurement	PLEC CLEC16A	2.13e-03	28	72	2	EFO_0010296
Disease	Neurotoxicity Syndromes	NQO1 ABCB1	2.28e-03	29	72	2	C0235032
Disease	Encephalopathy, Toxic	NQO1 ABCB1	2.28e-03	29	72	2	C0149504
Disease	Toxic Encephalitis	NQO1 ABCB1	2.28e-03	29	72	2	C0154659
Disease	hepatocellular carcinoma (biomarker_via_orthology)	ABCA1 XDH ABCB1	2.37e-03	108	72	3	DOID:684 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
GIALWGGEKFKQIQR	EIF3B	356	P55884
GGSWKFLTFIDLVIQ	AIG1	36	Q9NVV5
DIALLGFLGVQRKFW	ALS2	1516	Q96Q42
FWQFFVRLCGIVGGI	ERGIC2	311	Q96RQ1
LLDERKFWAGIVFTG	ABCA1	526	O95477
VLQEIVGKGRFGEVW	ACVR1C	196	Q8NER5
KQIFLGGVDKRTQFW	SLC25A5	96	P05141
IRKGIVMGFFTGFVW	ABCB11	316	O95342
WRQGVLVAGFRLGVT	FAM187A	346	A6NFU0
GIWFDILSGIGKFSV	ANO2	801	Q9NQ90
WFYVGEIIGKRGIIG	ATP5MG	86	O75964
VIAGGIFVIDKSWFN	GALNT16	291	Q8N428
RFLKNIGWGTDQGIG	IER3IP1	26	Q9Y5U9
FTGFIVGFTRGWKLT	ABCB1	201	P08183
LLLGVGTFVVLRFWG	MUC4	5381	Q99102
EFWRKFGIGLLSGTI	SLC25A21	206	Q9BQT8
FWKEFGTNIKLGVIE	HSP90B2P	141	Q58FF3
LGFKGVWKGLFARII	SLC25A3	306	Q00325
DIFLWRKETGFGFRI	MAGI1	841	Q96QZ7
WIDFVRGAKEGIILF	SSB	261	P05455
FVFSLGTGQVIKGWD	FKBP2	76	P26885
SLEFRKQAGGVDIGW	ENTPD8	426	Q5MY95
EFRVEVLFWGLRGLG	FER1L4	936	A9Z1Z3
LVFIFKGNQFWAIRG	MMP3	351	P08254
LQEIGSGWFGKVILG	LMTK3	136	Q96Q04
GFIDWVKNSGGRVLV	DUSP2	241	Q05923
GVAVGGFVLWKGIQR	EXD2	16	Q9NVH0
KLVERLGAGQFGEVW	LCK	246	P06239
IVGIFVLQKWRLGGI	GDPD5	511	Q8WTR4
QFDLWVLRGVLNFGG	PRSS54	231	Q6PEW0
REFWKQLGNLGVLGI	IVD	81	P26440
DFLGRGTFGQVVKCW	HIPK3	201	Q9H422
FWLKVGAGVGAFTAV	ELAPOR2	926	A8MWY0
EWQKIGVGITGFGIF	GOLT1A	6	Q6ZVE7
TWLKGLRGFFFVGVL	SLC48A1	66	Q6P1K1
AILKGWFERVFIGEF	NQO1	111	P15559
FIVGFIRGWKLTLVI	ABCB4	206	P21439
FKELGTGNRIATWLF	P4HA1	441	P13674
VWLQVTGGERFNGLF	C1QTNF9	301	P0C862
LLKRLGSGQFGEVWE	FRK	236	P42685
WKGLVRFLNSLGTIF	CPTP	36	Q5TA50
GGKVWLSVLFIFRIL	GJA1	21	P17302
EGGKGSVFQRVLSWI	RAP1GDS1	311	P52306
FLDNVGWFVRKLSGL	C3orf80	71	F5H4A9
IEGWKVATGQVTGFF	GALNT17	231	Q6IS24
RTFNVGDLVWGQIKG	MBD5	1381	Q9P267
FASRGIGWLVAQEGV	ASNSD1	466	Q9NWL6
FIVENGWFVSGTTKR	KL	411	Q9UEF7
RFGRKWSQLGTLVLG	SLC22A13	386	Q9Y226
ILIFEGANKIGLFFW	EPB41L4B	296	Q9H329
GKIQIWERKFGFEIS	MTBP	241	Q96DY7
IGFLTSGWRFVQIKE	MRPL41	41	Q8IXM3
KGITLFRQGDIGTNW	RAPGEF4	66	Q8WZA2
VIFSRSWAGDVGFRK	SLFN14	436	P0C7P3
VLGVVFGKGNTAFWI	SIDT2	621	Q8NBJ9
FFLTWRSEGKEGQVL	PLCB4	46	Q15147
IGRGWFGKVFLGEVN	AATK	131	Q6ZMQ8
WEGAFLDRVLGIRGQ	ABCC6	506	O95255
GNGLVLWFFGFSIKR	MRGPRF	61	Q96AM1
LFIRLSWIVGEAGIG	SLC12A1	196	Q13621
VLQESIGKGRFGEVW	TGFBR1	206	P36897
EGWLFGRIGCKVLSF	BRS3	111	P32247
VSRLGWGVVKFAGLL	CLEC16A	741	Q2KHT3
EKEQGVVRKAGWLFF	TIAM2	501	Q8IVF5
GFIEVWNFTTGKIRK	SMU1	236	Q2TAY7
GRGRVGLWKDIFTVS	SULT4A1	246	Q9BR01
IIGGFWETIFGNRIK	PHTF1	196	Q9UMS5
QFNKEILLGRGFTFW	STAT6	501	P42226
VLGVLGLTWFINKFR	SLC9A1	426	P19634
VFRGVLEQLRWFAGK	XDH	326	P47989
GGFKGRTVTVWELIS	PLEC	3381	Q15149
GGRRWIKQMFIGAFL	TM9SF3	351	Q9HD45
LEAFGGFIAFIRLWV	SLC7A6	116	Q92536
LSVVWRQGKGDFFLG	TLCD3B	146	Q71RH2
WFRKFVAERGAVGTS	ZMYND15	21	Q9H091
FQGVEILWTGGDKRE	PSD3	301	Q9NYI0