Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

DNAH3 DNAH10 ATP13A1 SEPTIN9 RHOBTB3 PSMC6 RGS9 CHD7 DHX33 RRAGC ORC4 EEF2 ABCB9 DNM3 ABCC12 POLQ MX2

6.12e-0677512417GO:0017111
GeneOntologyMolecularFunctionpyrophosphatase activity

DNAH3 DNAH10 ATP13A1 SEPTIN9 RHOBTB3 PSMC6 RGS9 CHD7 DHX33 RRAGC ORC4 EEF2 ABCB9 DNM3 ABCC12 POLQ MX2

1.71e-0583912417GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

DNAH3 DNAH10 ATP13A1 SEPTIN9 RHOBTB3 PSMC6 RGS9 CHD7 DHX33 RRAGC ORC4 EEF2 ABCB9 DNM3 ABCC12 POLQ MX2

1.74e-0584012417GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

DNAH3 DNAH10 ATP13A1 SEPTIN9 RHOBTB3 PSMC6 RGS9 CHD7 DHX33 RRAGC ORC4 EEF2 ABCB9 DNM3 ABCC12 POLQ MX2

1.74e-0584012417GO:0016818
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RASGRF1 ARHGAP10 ARHGAP26 FRMD7 ARFGEF2 RGS9 RCC2 NRP1 TBC1D4 RIN2 HERC2 MCF2L

7.64e-0550712412GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RASGRF1 ARHGAP10 ARHGAP26 FRMD7 ARFGEF2 RGS9 RCC2 NRP1 TBC1D4 RIN2 HERC2 MCF2L

7.64e-0550712412GO:0030695
GeneOntologyMolecularFunctionATP hydrolysis activity

DNAH3 DNAH10 ATP13A1 RHOBTB3 PSMC6 CHD7 DHX33 ORC4 ABCB9 ABCC12 POLQ

9.71e-0544112411GO:0016887
GeneOntologyMolecularFunctionATP-dependent activity

DNAH3 DNAH10 ATP13A1 RHOBTB3 PSMC6 CHD7 DHX33 MYO5C ORC4 ABCB9 DNAH17 ABCC12 POLQ

1.17e-0461412413GO:0140657
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH3 DNAH10 DNAH17

1.78e-04181243GO:0008569
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE1 SYNE2

3.78e-0451242GO:0140444
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

RASGRF1 FRMD7 ARFGEF2 RCC2 RIN2 HERC2 MCF2L

6.06e-042311247GO:0005085
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH3 DNAH10 DNAH17

6.84e-04281243GO:0051959
GeneOntologyMolecularFunctionactin binding

SYNE1 CAMSAP3 MYOZ2 ACTR2 MYO5C EEF2 DST SVIL SYNE2 UTRN

8.19e-0447912410GO:0003779
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH3 DNAH10 DNAH17

1.56e-03371243GO:0045505
GeneOntologyMolecularFunctionrDNA binding

DHX33 MTOR

1.67e-03101242GO:0000182
GeneOntologyBiologicalProcesscilium movement

DNAH3 DNAH10 CAMSAP3 CFAP43 FSIP2 OR4M2 SLC9C1 DNAH17 VPS13A IQCG

4.39e-0626112510GO:0003341
GeneOntologyBiologicalProcesscilium movement involved in cell motility

DNAH3 DNAH10 CFAP43 FSIP2 OR4M2 SLC9C1 DNAH17 VPS13A IQCG

5.46e-062101259GO:0060294
GeneOntologyBiologicalProcesscilium-dependent cell motility

DNAH3 DNAH10 CFAP43 FSIP2 OR4M2 SLC9C1 DNAH17 VPS13A IQCG

6.61e-062151259GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

DNAH3 DNAH10 CFAP43 FSIP2 OR4M2 SLC9C1 DNAH17 VPS13A IQCG

6.61e-062151259GO:0001539
GeneOntologyBiologicalProcessmicrotubule-based movement

DNAH3 DNAH10 CAMSAP3 CFAP43 ACTR2 FSIP2 OR4M2 SLC9C1 DST DNAH17 SYNE2 VPS13A IQCG

9.52e-0649312513GO:0007018
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection assembly

SEPTIN9 SYNE1 FRMD7 RCC2 ACTR2 NRP1 MTOR SYNE2 DNM3

2.07e-052481259GO:0120032
GeneOntologyBiologicalProcessregulation of cell projection assembly

SEPTIN9 SYNE1 FRMD7 RCC2 ACTR2 NRP1 MTOR SYNE2 DNM3

2.27e-052511259GO:0060491
GeneOntologyBiologicalProcesspositive regulation of cellular component biogenesis

CUX2 WARS1 SEPTIN9 FRMD7 CASP5 PSMC6 DHX33 ACTR2 NRP1 PTK2B MTOR SNX7 DNM3

5.36e-0558212513GO:0044089
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

SEPTIN9 SYNE1 FRMD7 CFAP43 RCC2 ACTR2 NRP1 FSIP2 MTOR DNAH17 SYNE2 DNM3 CC2D2A IQCG

5.61e-0567012514GO:0120031
GeneOntologyBiologicalProcesscell projection assembly

SEPTIN9 SYNE1 FRMD7 CFAP43 RCC2 ACTR2 NRP1 FSIP2 MTOR DNAH17 SYNE2 DNM3 CC2D2A IQCG

7.11e-0568512514GO:0030031
GeneOntologyBiologicalProcesspositive regulation of plasma membrane bounded cell projection assembly

SEPTIN9 FRMD7 ACTR2 NRP1 MTOR DNM3

1.05e-041231256GO:0120034
GeneOntologyBiologicalProcessbasal dendrite arborization

NRP1 SEMA3A

1.09e-0431252GO:0150020
GeneOntologyBiologicalProcessfacioacoustic ganglion development

NRP1 SEMA3A

1.09e-0431252GO:1903375
GeneOntologyBiologicalProcessbasal dendrite morphogenesis

NRP1 SEMA3A

1.09e-0431252GO:0150019
GeneOntologyBiologicalProcessbasal dendrite development

NRP1 SEMA3A

1.09e-0431252GO:0150018
GeneOntologyBiologicalProcessintegrin-mediated signaling pathway

ITGA1 RCC2 NRP1 NEDD9 PTK2B DST

1.09e-041241256GO:0007229
GeneOntologyBiologicalProcessregulation of double-strand break repair via homologous recombination

EPC2 TEX15 ACTR2 MORF4L1 POLQ

1.50e-04831255GO:0010569
GeneOntologyBiologicalProcesscilium organization

SEPTIN9 SYNE1 RTTN CFAP43 ACTR2 NEDD9 FSIP2 DNAH17 SYNE2 CC2D2A IQCG

1.54e-0447612511GO:0044782
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

CUX2 SEPTIN9 SYNE1 FRMD7 RCC2 ACTR2 NRP1 SEMA3A NEDD9 PTK2B PTPRG MTOR SYNE2 DNM3 CDH2

1.87e-0484612515GO:0120035
GeneOntologyBiologicalProcessventral trunk neural crest cell migration

NRP1 SEMA3A

2.17e-0441252GO:0036486
GeneOntologyBiologicalProcesssympathetic neuron projection guidance

NRP1 SEMA3A

2.17e-0441252GO:0097491
GeneOntologyBiologicalProcessregulation of cell-matrix adhesion

CAMSAP3 RCC2 NRP1 PTK2B RIN2 UTRN

2.21e-041411256GO:0001952
GeneOntologyBiologicalProcessmicrotubule-based process

DNAH3 DNAH10 RTTN CAMSAP3 CFAP43 ACTR2 FSIP2 OR4M2 SLC9C1 DST DNAH17 SYNE2 VPS13A CC2D2A CENATAC PPP2R3C IQCG

2.21e-04105812517GO:0007017
GeneOntologyBiologicalProcessregulation of cell projection organization

CUX2 SEPTIN9 SYNE1 FRMD7 RCC2 ACTR2 NRP1 SEMA3A NEDD9 PTK2B PTPRG MTOR SYNE2 DNM3 CDH2

2.32e-0486312515GO:0031344
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

CUX2 WARS1 SEPTIN9 SYNE1 FRMD7 CAMSAP3 CASP5 PSMC6 DHX33 RCC2 ACTR2 NRP1 PTK2B MTOR SNX7 SVIL SYNE2 DNM3

2.95e-04118912518GO:0044087
GeneOntologyBiologicalProcesstrigeminal ganglion development

NRP1 SEMA3A

3.60e-0451252GO:0061551
GeneOntologyBiologicalProcessdichotomous subdivision of terminal units involved in salivary gland branching

NRP1 SEMA3A

3.60e-0451252GO:0060666
GeneOntologyBiologicalProcesssmall GTPase-mediated signal transduction

RASGRF1 ARHGAP10 ARHGAP26 FRMD7 ARFGEF2 RRAGC BRAP NRP1 RIN2 MCF2L CDH2

4.37e-0453812511GO:0007264
GeneOntologyBiologicalProcesscell-substrate junction assembly

CAMSAP3 RCC2 NRP1 PTK2B DST

5.11e-041081255GO:0007044
GeneOntologyBiologicalProcessaxoneme assembly

CFAP43 FSIP2 DNAH17 CC2D2A IQCG

5.33e-041091255GO:0035082
GeneOntologyBiologicalProcesstrunk neural crest cell migration

NRP1 SEMA3A

5.38e-0461252GO:0036484
GeneOntologyBiologicalProcesssympathetic neuron projection extension

NRP1 SEMA3A

5.38e-0461252GO:0097490
GeneOntologyBiologicalProcesstrunk segmentation

NRP1 SEMA3A

5.38e-0461252GO:0035290
GeneOntologyBiologicalProcesscranial ganglion development

NRP1 SEMA3A

5.38e-0461252GO:0061550
GeneOntologyBiologicalProcesstrigeminal nerve morphogenesis

NRP1 SEMA3A

5.38e-0461252GO:0021636
GeneOntologyBiologicalProcesstrigeminal nerve structural organization

NRP1 SEMA3A

5.38e-0461252GO:0021637
GeneOntologyBiologicalProcesscell-substrate junction organization

CAMSAP3 RCC2 NRP1 PTK2B DST

6.80e-041151255GO:0150115
GeneOntologyBiologicalProcessgonadotrophin-releasing hormone neuronal migration to the hypothalamus

NRP1 SEMA3A

7.50e-0471252GO:0021828
GeneOntologyBiologicalProcesshypothalamic tangential migration using cell-axon interactions

NRP1 SEMA3A

7.50e-0471252GO:0021856
GeneOntologyBiologicalProcessbranchiomotor neuron axon guidance

NRP1 SEMA3A

7.50e-0471252GO:0021785
GeneOntologyBiologicalProcessneural crest cell migration involved in autonomic nervous system development

NRP1 SEMA3A

7.50e-0471252GO:1901166
GeneOntologyCellularComponentmotile cilium

DNAH3 DNAH10 CAMSAP3 CFAP43 FSIP2 SLC9C1 MROH2B DNAH17 VPS13A PCDH11X IQCG

8.87e-0635512411GO:0031514
GeneOntologyCellularComponent9+2 motile cilium

DNAH3 DNAH10 CFAP43 FSIP2 MROH2B DNAH17 VPS13A PCDH11X IQCG

1.26e-052381249GO:0097729
GeneOntologyCellularComponentfocal adhesion

TES ARHGAP26 ITGA1 ACTR2 NRP1 NEDD9 PTK2B DST SVIL SYNE2 CDH2

5.28e-0543112411GO:0005925
GeneOntologyCellularComponentcell-substrate junction

TES ARHGAP26 ITGA1 ACTR2 NRP1 NEDD9 PTK2B DST SVIL SYNE2 CDH2

6.75e-0544312411GO:0030055
GeneOntologyCellularComponentmicrotubule

DNAH3 DNAH10 SEPTIN9 CAMSAP3 ARFGEF2 RCC2 DST SVIL DNAH17 DNM3 EIF3A MX2

7.97e-0553312412GO:0005874
GeneOntologyCellularComponentcilium

DNAH3 DNAH10 SEPTIN9 RTTN CAMSAP3 ARFGEF2 CFAP43 NEDD9 FSIP2 SLC9C1 MROH2B DNAH17 VPS13A PCDH11X CC2D2A IQCG

8.30e-0589812416GO:0005929
GeneOntologyCellularComponentaxoneme

DNAH3 DNAH10 SEPTIN9 CAMSAP3 ARFGEF2 CFAP43 DNAH17

2.39e-042071247GO:0005930
GeneOntologyCellularComponentciliary plasm

DNAH3 DNAH10 SEPTIN9 CAMSAP3 ARFGEF2 CFAP43 DNAH17

2.46e-042081247GO:0097014
GeneOntologyCellularComponentaxonemal dynein complex

DNAH3 DNAH10 DNAH17

4.26e-04251243GO:0005858
GeneOntologyCellularComponentsperm midpiece

FSIP2 MROH2B VPS13A PCDH11X

5.69e-04641244GO:0097225
GeneOntologyCellularComponentsupramolecular fiber

DNAH3 DNAH10 SEPTIN9 SYNE1 CAMSAP3 MYOZ2 ARFGEF2 RCC2 RYR1 NRP1 DST SVIL DNAH17 SYNE2 DNM3 EIF3A MX2

5.99e-04117912417GO:0099512
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

DNAH3 DNAH10 SEPTIN9 CAMSAP3 ARFGEF2 CFAP43 DST DNAH17

6.15e-043171248GO:0032838
GeneOntologyCellularComponentsupramolecular polymer

DNAH3 DNAH10 SEPTIN9 SYNE1 CAMSAP3 MYOZ2 ARFGEF2 RCC2 RYR1 NRP1 DST SVIL DNAH17 SYNE2 DNM3 EIF3A MX2

6.46e-04118712417GO:0099081
GeneOntologyCellularComponentmicrotubule minus-end

CAMSAP3 SVIL

7.19e-0471242GO:0036449
GeneOntologyCellularComponentcytoplasmic region

DNAH3 DNAH10 SEPTIN9 CAMSAP3 ARFGEF2 CFAP43 DST DNAH17

1.39e-033601248GO:0099568
GeneOntologyCellularComponentmicrotubule end

CAMSAP3 DST SVIL

1.48e-03381243GO:1990752
GeneOntologyCellularComponentinner dynein arm

DNAH3 DNAH10

1.52e-03101242GO:0036156
GeneOntologyCellularComponentnuclear outer membrane

SYNE1 ITPR3 SYNE2

1.71e-03401243GO:0005640
GeneOntologyCellularComponentsperm flagellum

FSIP2 MROH2B DNAH17 VPS13A PCDH11X IQCG

1.76e-032141246GO:0036126
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE1 SYNE2

1.85e-03111242GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE1 SYNE2

1.85e-03111242GO:0106094
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE1 SYNE2

1.85e-03111242GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE1 SYNE2

1.85e-03111242GO:0034993
GeneOntologyCellularComponentasymmetric synapse

ARFGEF2 RGS9 HNRNPD SEMA3A PTK2B DST DNM3 EIF3A CDH2

2.18e-034771249GO:0032279
GeneOntologyCellularComponentcytoplasmic side of membrane

RYR1 ITPR3 ESYT3 DST AP4B1 MCF2L

2.52e-032301246GO:0098562
GeneOntologyCellularComponentlamellipodium

ACTR2 NEDD9 PTK2B SYNE2 MCF2L CDH2

2.52e-032301246GO:0030027
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

DNAH3 DNAH10 SEPTIN9 CAMSAP3 ARFGEF2 RCC2 NRP1 DST SVIL DNAH17 DNM3 EIF3A MX2

2.65e-0389912413GO:0099513
DomainSpectrin

SYNE1 DST SYNE2 MCF2L UTRN

3.35e-07231225PF00435
DomainSpectrin_repeat

SYNE1 DST SYNE2 MCF2L UTRN

1.15e-06291225IPR002017
DomainSPEC

SYNE1 DST SYNE2 MCF2L UTRN

1.91e-06321225SM00150
DomainSpectrin/alpha-actinin

SYNE1 DST SYNE2 MCF2L UTRN

1.91e-06321225IPR018159
DomainCH

SYNE1 CAMSAP3 LRCH3 DST SYNE2 UTRN

6.40e-06701226PF00307
DomainCH

SYNE1 CAMSAP3 LRCH3 DST SYNE2 UTRN

8.17e-06731226PS50021
DomainCH-domain

SYNE1 CAMSAP3 LRCH3 DST SYNE2 UTRN

9.57e-06751226IPR001715
DomainACTININ_2

SYNE1 DST SYNE2 UTRN

1.39e-05231224PS00020
DomainACTININ_1

SYNE1 DST SYNE2 UTRN

1.39e-05231224PS00019
DomainActinin_actin-bd_CS

SYNE1 DST SYNE2 UTRN

1.39e-05231224IPR001589
DomainCH

SYNE1 LRCH3 DST SYNE2 UTRN

6.61e-05651225SM00033
Domain-

SYNE1 LRCH3 DST SYNE2 UTRN

1.01e-047112251.10.418.10
Domain-

DNAH3 DNAH10 SEPTIN9 RHOBTB3 PSMC6 CHD7 DHX33 RRAGC ORC4 EEF2 ABCB9 DNM3 ABCC12 POLQ MX2

1.06e-04746122153.40.50.300
DomainP-loop_NTPase

DNAH3 DNAH10 SEPTIN9 RHOBTB3 PSMC6 CHD7 DHX33 RRAGC MYO5C ORC4 EEF2 ABCB9 DNM3 ABCC12 POLQ MX2

1.29e-0484812216IPR027417
DomainKASH

SYNE1 SYNE2

2.52e-0441222IPR012315
DomainKASH

SYNE1 SYNE2

2.52e-0441222PS51049
DomainKASH

SYNE1 SYNE2

2.52e-0441222SM01249
DomainKASH

SYNE1 SYNE2

2.52e-0441222PF10541
DomainAAA

DNAH3 DNAH10 PSMC6 ORC4 ABCB9 ABCC12

3.67e-041441226SM00382
DomainAAA+_ATPase

DNAH3 DNAH10 PSMC6 ORC4 ABCB9 ABCC12

3.67e-041441226IPR003593
DomainWHEP_TRS_1

EPRS1 WARS1

4.18e-0451222PS00762
DomainWHEP-TRS

EPRS1 WARS1

4.18e-0451222SM00991
DomainWHEP-TRS

EPRS1 WARS1

4.18e-0451222PF00458
DomainWHEP-TRS_dom

EPRS1 WARS1

4.18e-0451222IPR000738
DomainWHEP_TRS_2

EPRS1 WARS1

4.18e-0451222PS51185
DomainDynamin_central

DNM3 MX2

6.24e-0461222IPR000375
DomainRIH_assoc-dom

RYR1 ITPR3

6.24e-0461222IPR013662
DomainGED

DNM3 MX2

6.24e-0461222SM00302
DomainDynamin_M

DNM3 MX2

6.24e-0461222PF01031
DomainGED_dom

DNM3 MX2

6.24e-0461222IPR020850
DomainIns145_P3_rec

RYR1 ITPR3

6.24e-0461222PF08709
DomainRIH_assoc

RYR1 ITPR3

6.24e-0461222PF08454
DomainRIH_dom

RYR1 ITPR3

6.24e-0461222IPR000699
DomainIns145_P3_rcpt

RYR1 ITPR3

6.24e-0461222IPR014821
DomainRyanodine_recept-rel

RYR1 ITPR3

6.24e-0461222IPR015925
DomainGED

DNM3 MX2

6.24e-0461222PS51388
Domain-

RYR1 ITPR3

6.24e-04612221.25.10.30
DomainDynamin_GTPase_CS

DNM3 MX2

6.24e-0461222IPR019762
DomainRYDR_ITPR

RYR1 ITPR3

6.24e-0461222PF01365
DomainGED

DNM3 MX2

6.24e-0461222PF02212
DomainGED

DNM3 MX2

6.24e-0461222IPR003130
Domain-

EPRS1 WARS1

6.24e-04612221.10.287.10
DomainG_DYNAMIN_1

DNM3 MX2

8.70e-0471222PS00410
DomainDYNc

DNM3 MX2

8.70e-0471222SM00053
DomainS15_NS1_RNA-bd

EPRS1 WARS1

1.15e-0381222IPR009068
DomainMIR

RYR1 ITPR3

1.84e-03101222PF02815
DomainMIR_motif

RYR1 ITPR3

1.84e-03101222IPR016093
DomainMIR

RYR1 ITPR3

1.84e-03101222PS50919
DomainMIR

RYR1 ITPR3

1.84e-03101222SM00472
DomainSH3

ARHGAP10 ARHGAP26 NEDD9 DST MCF2L TP53BP2

2.97e-032161226PS50002
DomainI-BAR_dom

ARHGAP10 ARHGAP26

3.15e-03131222IPR013606
DomainSH3_domain

ARHGAP10 ARHGAP26 NEDD9 DST MCF2L TP53BP2

3.25e-032201226IPR001452
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH10

3.66e-03141222IPR024317
DomainDynein_HC_stalk

DNAH3 DNAH10

3.66e-03141222IPR024743
DomainDynein_heavy_dom-2

DNAH3 DNAH10

3.66e-03141222IPR013602
DomainG_DYNAMIN_dom

DNM3 MX2

3.66e-03141222IPR030381
DomainDHC_N2

DNAH3 DNAH10

3.66e-03141222PF08393
DomainATPase_dyneun-rel_AAA

DNAH3 DNAH10

3.66e-03141222IPR011704
DomainMT

DNAH3 DNAH10

3.66e-03141222PF12777
DomainAAA_8

DNAH3 DNAH10

3.66e-03141222PF12780
DomainG_DYNAMIN_2

DNM3 MX2

3.66e-03141222PS51718
DomainAAA_5

DNAH3 DNAH10

3.66e-03141222PF07728
DomainDHC_fam

DNAH3 DNAH10

4.20e-03151222IPR026983
DomainDynamin_GTPase

DNM3 MX2

4.20e-03151222IPR001401
DomainDynamin_SF

DNM3 MX2

4.20e-03151222IPR022812
DomainDynein_heavy

DNAH3 DNAH10

4.20e-03151222PF03028
DomainDynamin_N

DNM3 MX2

4.20e-03151222PF00350
DomainDynein_heavy_dom

DNAH3 DNAH10

4.20e-03151222IPR004273
DomainSH3_1

ARHGAP10 ARHGAP26 NEDD9 DST TP53BP2

4.46e-031641225PF00018
DomainCadherin_CS

FAT4 PCDHGA1 PCDH11X CDH2

5.69e-031091224IPR020894
Domainaa-tRNA-synth_I_CS

EPRS1 WARS1

6.05e-03181222IPR001412
DomainZF_ZZ_2

HERC2 UTRN

6.05e-03181222PS50135
DomainZF_ZZ_1

HERC2 UTRN

6.05e-03181222PS01357
DomainZZ

HERC2 UTRN

6.05e-03181222PF00569
DomainCADHERIN_1

FAT4 PCDHGA1 PCDH11X CDH2

6.46e-031131224PS00232
DomainCadherin

FAT4 PCDHGA1 PCDH11X CDH2

6.46e-031131224PF00028
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

EPRS1 DNAH3 FAT4 ZNF775 SEPTIN9 CAMSAP3 NELFB TMEM132B RYR1 HNRNPL ASB18 TBC1D4 DST CLNS1A ARID5B VPS13A MLLT1 EIF3A UTRN

2.34e-117361261929676528
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

EPRS1 DMXL2 VWF WARS1 SEPTIN9 SYNE1 ARHGAP26 CAMSAP3 ARFGEF2 HNRNPD ACTR2 LRCH3 PTK2B EPS15L1 EEF2 DST SVIL EIF3A CDH2 UTRN TP53BP2 HDLBP

9.51e-0914311262237142655
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

EPRS1 SEPTIN9 SYNE1 RCC2 HNRNPD ACTR2 HNRNPL MYO5C NRP1 ITPR3 DST SVIL SYNE2 MKI67 EIF3A HERC2 UTRN HDLBP

3.35e-0810241261824711643
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

EPRS1 DMXL2 VWF WASHC4 WARS1 ATP13A1 SYNE1 RHOBTB3 ARFGEF2 EPS15L1 EEF2 DST MORF4L1 VPS35L ARID5B DNM3 CCDC15 HERC2 UTRN UAP1L1

3.99e-0812851262035914814
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

EPRS1 TES WASHC4 WARS1 NELFB ARFGEF2 PSMC6 POLE3 COG3 RCC2 HNRNPD ACTR2 EPS15L1 EEF2 TBC1D4 PPP6C MTOR CLNS1A PLA2G4A EIF3A HDLBP

6.30e-0814551262122863883
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

EPRS1 SEPTIN9 SYNE1 DHX33 RCC2 HNRNPD ACTR2 HNRNPL LRCH3 MYO5C ITPR3 NEDD9 EEF2 DST SVIL MKI67 EIF3A

6.38e-089491261736574265
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

DMXL2 SYNE1 CAMSAP3 CHD7 TMEM132B EPS15L1 EEF2 DST PPP6C MTOR MORF4L1 SVIL SYNE2 DNM3 HERC2 CDH2 TP53BP2

7.86e-089631261728671696
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

EPRS1 WASHC4 WARS1 SEPTIN9 PSMC6 CHD7 DHX33 RRM2 HNRNPD HNRNPL EEF2 TBC1D4 DST PPP6C MKI67 EIF3A HERC2 UTRN TP53BP2 HDLBP

9.20e-0813531262029467282
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

EPRS1 SEPTIN9 CAMSAP3 NELFB ARFGEF2 CHD7 HNRNPD EPS15L1 EEF2 TBC1D4 ABCB9 SVIL MKI67 PLA2G4A HDLBP

1.49e-077741261515302935
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

EPRS1 WARS1 SEPTIN9 CAMSAP3 PSMC6 POLE3 RCC2 HNRNPD ACTR2 HNRNPL EEF2 TBC1D4 DST PPP6C CLNS1A SVIL EIF3A HDLBP

1.86e-0711491261835446349
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

EPRS1 WARS1 SEPTIN9 SYNE1 COG3 HNRNPD ACTR2 RYR1 HNRNPL EEF2 DST ZNF561 EIF3A UTRN HDLBP

2.53e-078071261530575818
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ARHGAP10 CAMSAP3 PSMC6 HNRNPL ITPR3 TBC1D4 PPP6C PTPRG CLNS1A SVIL SYNE2 VPS13A MKI67 HERC2 UTRN TP53BP2 HDLBP

2.63e-0710491261727880917
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

DMXL2 VWF SYNE1 MYOZ2 RYR1 NEDD9 TBC1D4 DST MORF4L1 SYNE2 EIF3A UTRN

2.84e-074971261223414517
Pubmed

CAMSAP3 is required for mTORC1-dependent ependymal cell growth and lateral ventricle shaping in mouse brains.

CAMSAP3 MTOR MKI67 CDH2

4.83e-0718126433462112
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

EPRS1 SEPTIN9 PSMC6 POLE3 RCC2 ACTR2 HNRNPL BRAP ITPR3 EEF2 TBC1D4 PPP6C CLNS1A SVIL MKI67 MLLT1 TP53BP2 HDLBP

6.11e-0712471261827684187
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

EPRS1 PSMC6 PPWD1 ACTR2 EEF2 TBC1D4 DST PPP6C MTOR MKI67 EIF3A UTRN

6.55e-075381261228524877
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

EPRS1 CUX2 SYNE1 PCDHGA1 MAFA CAMSAP3 HNRNPD ACTR2 EEF2 DST ABCB9 SYNE2 VPS13A CC2D2A MLLT1 EIF3A MCF2L POLQ DNAJC5B

1.13e-0614421261935575683
Pubmed

EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

EPRS1 DNAH3 WARS1 SEPTIN9 SYNE1 PSMC6 HNRNPD ACTR2 HNRNPL EEF2 MKI67 EIF3A MX2 HDLBP

1.39e-068031261436517590
Pubmed

mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.

SEPTIN9 BRAP DST PTPRG SYNE2 HDLBP

1.61e-0698126634943047
Pubmed

CHD7, the gene mutated in CHARGE syndrome, regulates genes involved in neural crest cell guidance.

CHD7 SEMA3A TP53BP2

1.61e-067126324728844
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

DMXL2 WASHC4 ARFGEF2 COG3 RRAGC LRCH3 ITPR3 DST SYNE2 VPS35L VPS13A

2.41e-065041261134432599
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

EPRS1 EPC2 WARS1 SEPTIN9 NELFB PSMC6 CHD7 PPWD1 RCC2 HNRNPD ACTR2 HNRNPL EEF2 MORF4L1 MKI67 HDLBP

2.56e-0611031261634189442
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

EPRS1 ZNF775 WARS1 CAMSAP3 NELFB HNRNPD MTOR C7orf25 SNX7 SYNE2 MKI67 GPCPD1 HMGXB3 MCF2L TP53BP2 IQCG

3.25e-0611241261621900206
Pubmed

The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.

EPRS1 WARS1 RCC2 HNRNPD HNRNPL EEF2 MKI67 EIF3A HDLBP

3.48e-06330126932529326
Pubmed

Human transcription factor protein interaction networks.

EPC2 DNAH10 PSMC6 CHD7 RCC2 HNRNPL MYO5C DST PPP6C MORF4L1 SVIL SYNE2 ARID5B MKI67 MLLT1 EIF3A HERC2 ZNF471

4.16e-0614291261835140242
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

WARS1 CHD7 RCC2 ACTR2 ITPR3 DST MTOR SYNE2 MKI67 HERC2 UTRN HDLBP

4.82e-066531261222586326
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

CAMSAP3 PSMC6 HNRNPD ACTR2 HNRNPL EEF2 PPP6C MTOR CLNS1A VPS13A EIF3A HERC2

5.13e-066571261236180527
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

DNAH10 SYNE1 RTTN EEF2 DST SYNE2 EIF3A

5.72e-06187126726460568
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

EPRS1 WASHC4 NELFB PSMC6 POLE3 RCC2 HNRNPD ACTR2 HNRNPL ORC4 EEF2 TBC1D4 PPP6C MORF4L1 CLNS1A EIF3A HDLBP

6.86e-0613351261729229926
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

VIPR1 ARHGAP10 SEPTIN9 CAMSAP3 ACVR2B COG3 HNRNPL LRCH3 NRP1 EPS15L1 TBC1D4 PTPRG RIN2 VPS35L ARID5B MCF2L CENATAC UTRN

7.32e-0614891261828611215
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

TES WARS1 ATP13A1 BRAP ITPR3 EPS15L1 DST SYNE2 VPS13A PLA2G4A HDLBP

7.49e-065681261137774976
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

WARS1 PSMC6 HNRNPD BRAP ITPR3 EPS15L1 DST EIF3A HERC2 HDLBP

1.08e-054811261028190767
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ATP13A1 ARHGAP26 RTTN ARFGEF2 CFAP43 RYR1 ITPR3 EPS15L1 DST MTOR MLLT1 HMGXB3 HERC2 MCF2L PPP2R3C

1.18e-0511051261535748872
Pubmed

KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development.

SYNE1 SYNE2 MKI67

1.29e-0513126321177258
Pubmed

Semaphorin 3A - a marker for disease activity and a potential putative disease-modifying treatment in systemic lupus erythematosus.

NRP1 SEMA3A

1.30e-052126222875653
Pubmed

Semaphorin 3A mitigates lipopolysaccharide-induced chondrocyte inflammation, apoptosis and extracellular matrix degradation by binding to Neuropilin-1.

NRP1 SEMA3A

1.30e-052126234821196
Pubmed

Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging.

NRP1 SEMA3A

1.30e-052126230661929
Pubmed

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

SYNE1 SYNE2

1.30e-052126211792814
Pubmed

Brain endothelial cells control fertility through ovarian-steroid-dependent release of semaphorin 3A.

NRP1 SEMA3A

1.30e-052126224618750
Pubmed

Semaphorin 3A signaling through neuropilin-1 is an early trigger for distal axonopathy in the SOD1G93A mouse model of amyotrophic lateral sclerosis.

NRP1 SEMA3A

1.30e-052126224918638
Pubmed

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.

SYNE1 SYNE2

1.30e-052126224931616
Pubmed

Blockage of cytosolic phospholipase A2 alpha sensitizes aggressive breast cancer to doxorubicin through suppressing ERK and mTOR kinases.

MTOR PLA2G4A

1.30e-052126229307829
Pubmed

Axon position within the corpus callosum determines contralateral cortical projection.

NRP1 SEMA3A

1.30e-052126223812756
Pubmed

Pontocerebellar axon guidance: neuropilin-1- and semaphorin 3A-sensitivity gradients across basilar pontine nuclei and semaphorin 3A variation across cerebellum.

NRP1 SEMA3A

1.30e-052126212401447
Pubmed

Semaphorin-3A and its receptor neuropilin-1 are predominantly expressed in endothelial cells along the rostral migratory stream of young and adult mice.

NRP1 SEMA3A

1.30e-052126218574596
Pubmed

mTORC1 is a critical mediator of oncogenic Semaphorin3A signaling.

SEMA3A MTOR

1.30e-052126227246732
Pubmed

Control of human thymocyte migration by Neuropilin-1/Semaphorin-3A-mediated interactions.

NRP1 SEMA3A

1.30e-052126217369353
Pubmed

Heterogeneous nuclear ribonucleoprotein D/AUF1 interacts with heterogeneous nuclear ribonucleoprotein L.

HNRNPD HNRNPL

1.30e-052126218202450
Pubmed

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.

SYNE1 SYNE2

1.30e-052126222768332
Pubmed

The role of neuropilin-1/semaphorin 3A signaling in lymphatic vessel development and maturation.

NRP1 SEMA3A

1.30e-052126224276892
Pubmed

Decreased Expression of Semaphorin3A/Neuropilin-1 Signaling Axis in Apical Periodontitis.

NRP1 SEMA3A

1.30e-052126229457037
Pubmed

Transporters, TBC1D4, and ARID5B Variants to Explain Glycated Hemoglobin Variability in Patients with Type 2 Diabetes.

TBC1D4 ARID5B

1.30e-052126234265779
Pubmed

Recurrent Mutations in the MTOR Regulator RRAGC in Follicular Lymphoma.

RRAGC MTOR

1.30e-052126227267853
Pubmed

Semaphorin3A-neuropilin1 signalling is involved in the generation of cortical interneurons.

NRP1 SEMA3A

1.30e-052126227858201
Pubmed

The Neuropilin-1 Ligand, Sema3A, Acts as a Tumor Suppressor in the Pathogenesis of Acute Leukemia.

NRP1 SEMA3A

1.30e-052126230378769
Pubmed

Impeding macrophage entry into hypoxic tumor areas by Sema3A/Nrp1 signaling blockade inhibits angiogenesis and restores antitumor immunity.

NRP1 SEMA3A

1.30e-052126224332039
Pubmed

Neuron-derived semaphorin 3A is an early inducer of vascular permeability in diabetic retinopathy via neuropilin-1.

NRP1 SEMA3A

1.30e-052126224093675
Pubmed

Cis and trans interactions of L1 with neuropilin-1 control axonal responses to semaphorin 3A.

NRP1 SEMA3A

1.30e-052126212456642
Pubmed

Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.

SYNE1 SYNE2

1.30e-052126217267447
Pubmed

Nesprins: tissue-specific expression of epsilon and other short isoforms.

SYNE1 SYNE2

1.30e-052126224718612
Pubmed

Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

SYNE1 SYNE2

1.30e-052126224586179
Pubmed

Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A.

NRP1 SEMA3A

1.30e-052126216424390
Pubmed

Sema3A Alleviates the Malignant Behaviors of Gastric Cancer Cells by Inhibiting NRP-1.

NRP1 SEMA3A

1.30e-052126237533240
Pubmed

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

SYNE1 SYNE2

1.30e-052126217761684
Pubmed

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.

SYNE1 SYNE2

1.30e-052126231578382
Pubmed

Common allosteric mechanisms between ryanodine and inositol-1,4,5-trisphosphate receptors.

RYR1 ITPR3

1.30e-052126221150295
Pubmed

Sema3a plays a role in the pathogenesis of CHARGE syndrome.

CHD7 SEMA3A

1.30e-052126229432577
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

EPRS1 SEPTIN9 ARFGEF2 PSMC6 HNRNPD HNRNPL EEF2 PPP6C MKI67 EIF3A

1.35e-054941261026831064
Pubmed

LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway.

EPRS1 WARS1 SEPTIN9 EEF2 DST EIF3A

1.37e-05142126630809309
Pubmed

BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.

WARS1 SEPTIN9 BRAP EPS15L1 PLA2G4A EIF3A HDLBP

1.46e-05216126731519766
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

EPRS1 SEPTIN9 CAMSAP3 NELFB RRM2 EPS15L1 EEF2 TBC1D4 MKI67 PLA2G4A

1.58e-055031261016964243
Pubmed

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.

WARS1 ATP13A1 SEPTIN9 HNRNPD ACTR2 HNRNPL MTOR SVIL MKI67

1.62e-05400126935013556
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH3 DNAH10 DNAH17

1.64e-051412639373155
Pubmed

Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.

SEPTIN9 ITPR3 EIF3A HDLBP

1.82e-0543126434672947
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

PSMC6 COG3 PTGFRN RCC2 HNRNPD ACTR2 HNRNPL LRCH3 ITPR3 EEF2 DST PPP6C MTOR SYNE2 VPS35L MKI67 EIF3A

1.82e-0514401261730833792
Pubmed

Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.

CAMSAP3 PSMC6 HNRNPD HNRNPL EEF2 PPP6C CLNS1A VPS13A EIF3A

1.90e-05408126933766124
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

DMXL2 CUX2 SYNE1 CHD7 DST SYNE2 DNM3

1.90e-05225126712168954
Pubmed

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.

EPRS1 SEPTIN9 EEF2 MTOR SVIL EIF3A UAP1L1 HDLBP

1.93e-05312126837120454
Pubmed

Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development.

WARS1 HNRNPD ACTR2 EEF2 HDLBP

1.98e-0590126528978906
Pubmed

A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project.

RASGRF1 ARHGAP10 PTPRG

2.05e-0515126320031603
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

CHD7 PTGFRN PCDH11X GPCPD1 CC2D2A ZNF471

2.09e-05153126610718198
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

EPRS1 NELFB PSMC6 RRM2 RCC2 HNRNPD HNRNPL EEF2 TBC1D4 MTOR EIF3A

2.20e-056381261133239621
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

FAT4 ARHGAP26 CHD7 RYR1 ITPR3 SYNE2 ARID5B VPS13A C5 MCF2L PPP2R3C

2.20e-056381261131182584
Pubmed

Defining the membrane proteome of NK cells.

EPRS1 ATP13A1 ARFGEF2 PSMC6 ITGA1 ACTR2 HNRNPL ITPR3 EPS15L1 EEF2 MTOR MKI67 EIF3A HERC2 GNPAT

2.26e-0511681261519946888
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

DNAH3 SYNE1 DST PCDH11X MKI67 EIF3A UAP1L1

2.38e-05233126737704626
Pubmed

RBR-type E3 ubiquitin ligase RNF144A targets PARP1 for ubiquitin-dependent degradation and regulates PARP inhibitor sensitivity in breast cancer cells.

EPRS1 MYO5C EEF2 SVIL

2.60e-0547126429212245
Pubmed

The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells.

EPRS1 WARS1 SEPTIN9 HNRNPD HNRNPL EEF2 EIF3A

2.80e-05239126726641092
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ATP13A1 ARHGAP10 SYNE1 CAMSAP3 PSMC6 CHD7 DHX33 RCC2 LRCH3 ORC4 DST MORF4L1 MLLT1 EIF3A HERC2 UTRN HDLBP

2.98e-0514971261731527615
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

SEPTIN9 PPWD1 RCC2 ACTR2 HNRNPL RRAGC ITPR3 DST SVIL MKI67 EIF3A

2.99e-056601261132780723
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

EPRS1 TES WARS1 SEPTIN9 RCC2 BRAP EPS15L1 DST MKI67 EIF3A UTRN TP53BP2 HDLBP

3.63e-059341261333916271
Pubmed

Expression of semaphorin 3A and its receptors during mouse corneal development.

NRP1 SEMA3A

3.90e-053126221075075
Pubmed

Semaphorin-3a, neuropilin-1 and plexin-A1 in prosthetic-particle induced bone loss.

NRP1 SEMA3A

3.90e-053126226602825
Pubmed

SEMA3A partially reverses VEGF effects through binding to neuropilin-1.

NRP1 SEMA3A

3.90e-053126228636974
Pubmed

Age-dependent effects of secreted Semaphorins 3A, 3F, and 3E on developing hippocampal axons: in vitro effects and phenotype of Semaphorin 3A (-/-) mice.

NRP1 SEMA3A

3.90e-053126211461151
Pubmed

The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.

SYNE1 SYNE2

3.90e-053126216079285
Pubmed

Pre-target axon sorting establishes the neural map topography.

NRP1 SEMA3A

3.90e-053126219589963
Pubmed

Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells.

NRP1 SEMA3A

3.90e-053126214500350
Pubmed

Aberrant NRP-1 expression serves as predicator of metastatic endometrial and lung cancers.

NRP1 NEDD9

3.90e-053126226701889
Pubmed

CUX2, BRAP and ALDH2 are associated with metabolic traits in people with excessive alcohol consumption.

CUX2 BRAP

3.90e-053126233093602
Pubmed

Semaphorin3A Signaling Is Dispensable for Motor Axon Reinnervation of the Adult Neuromuscular Junction.

NRP1 SEMA3A

3.90e-053126229774231
InteractionRNF123 interactions

EPRS1 DNAH3 FAT4 ZNF775 SEPTIN9 CAMSAP3 NELFB TMEM132B RYR1 HNRNPL ASB18 TBC1D4 DST CLNS1A ARID5B VPS13A MLLT1 EIF3A UTRN

5.98e-0782412319int:RNF123
InteractionACTN4 interactions

EPRS1 TES SEPTIN9 MYOZ2 RGS9 HNRNPD ACTR2 HNRNPL MYO5C NRP1 SVIL MKI67 UTRN

1.04e-0640012313int:ACTN4
InteractionH3-4 interactions

EPRS1 VWF DNAH10 CFAP43 RCC2 HNRNPL ORC4 TBC1D4 MORF4L1 SVIL DNM3 MLLT1 HERC2

3.64e-0644812313int:H3-4
InteractionARHGAP10 interactions

ARHGAP10 ARHGAP26 HNRNPL PTK2B MKI67

4.91e-06411235int:ARHGAP10
InteractionCALD1 interactions

EPRS1 TES ACTR2 HNRNPL LRCH3 MYO5C ITPR3 DST SVIL EIF3A

5.31e-0626512310int:CALD1
InteractionCCDC8 interactions

EPRS1 RCC2 HNRNPL MYO5C NRP1 ITPR3 DST SVIL ARID5B MKI67 EIF3A HERC2 DNAJC5B UTRN HDLBP

1.13e-0565612315int:CCDC8
InteractionKCTD13 interactions

EPRS1 DMXL2 VWF WARS1 SEPTIN9 SYNE1 ARHGAP26 CAMSAP3 ARFGEF2 HNRNPD ACTR2 LRCH3 PTK2B EPS15L1 EEF2 DST SVIL EIF3A CDH2 UTRN TP53BP2 HDLBP

3.39e-05139412322int:KCTD13
InteractionOBSL1 interactions

SEPTIN9 SYNE1 RTTN RCC2 HNRNPD ACTR2 HNRNPL ITPR3 SLC9C1 DST SYNE2 MKI67 EIF3A HERC2 POLQ UTRN HDLBP

3.43e-0590212317int:OBSL1
InteractionTRPM2 interactions

HNRNPL ITPR3 HDLBP

3.53e-05111233int:TRPM2
InteractionIL1R2 interactions

ATP13A1 RHOBTB3 ORC4 DNM3 GNPAT

4.13e-05631235int:IL1R2
InteractionDNAH3 interactions

DNAH3 HNRNPD MKI67

4.69e-05121233int:DNAH3
InteractionEED interactions

EPRS1 EPC2 WASHC4 WARS1 SEPTIN9 CHD7 DHX33 POLE3 PPWD1 HNRNPD ACTR2 HNRNPL PTK2B EPS15L1 EEF2 SNX7 SVIL VPS35L EIF3A HERC2 UAP1L1 HDLBP

5.82e-05144512322int:EED
InteractionDISC1 interactions

ATP13A1 SYNE1 ITGA1 POLR3C SEMA3A EEF2 DST SVIL HERC2 AP4B1 UTRN

6.51e-0542912311int:DISC1
Cytoband16p12.3

DNAH3 TMC7 VPS35L

1.13e-0434126316p12.3
GeneFamilyDyneins, axonemal

DNAH3 DNAH10 DNAH17

9.06e-0517953536
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE1 SYNE2

1.63e-0449521252
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

CAMSAP3 RYR1 ITPR3 PCDH11X MKI67 TP53BP2

3.85e-04181956694
CoexpressionZHENG_BOUND_BY_FOXP3

VWF CHD7 RRM2 NRP1 IFNAR2 PTK2B EPS15L1 TBC1D4 SYNE2 ARID5B CC2D2A UTRN

4.50e-0649812412M1741
CoexpressionGSE24574_NAIVE_VS_TCONV_CD4_TCELL_UP

VIPR1 SYNE1 RGS9 ACVR2B DNM3 MCF2L CDH2 UTRN

5.16e-062001248M8328
CoexpressionZHENG_BOUND_BY_FOXP3

VWF CHD7 RRM2 NRP1 IFNAR2 PTK2B EPS15L1 TBC1D4 SYNE2 ARID5B CC2D2A UTRN

5.40e-0650712412MM1030
CoexpressionMURARO_PANCREAS_BETA_CELL

EPRS1 DMXL2 WARS1 RASGRF1 MAFA ARFGEF2 PSMC6 CHD7 TMEM132B RRAGC ITPR3 EEF2 TBC1D4 DST SYNE2 UTRN

1.04e-0594612416M39169
CoexpressionBUSSLINGER_ESOPHAGEAL_PROLIFERATING_BASAL_CELLS

RRM2 EEF2 DST SYNE2 MKI67

2.07e-05701245M40002
CoexpressionRODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP

EPRS1 WASHC4 WARS1 RHOBTB3 ARFGEF2 PPWD1 RCC2 ACTR2 BRAP POLR3C SEMA3A PPP2R3C CDH2

3.86e-0572112413M10237
CoexpressionGSE40273_XBP1_KO_VS_WT_TREG_DN

SEPTIN9 SYNE1 CHD7 VPS13A MKI67 HERC2 RASSF4

4.65e-051991247M9124
CoexpressionGSE9037_WT_VS_IRAK4_KO_LPS_1H_STIM_BMDM_UP

EPC2 TES PTPRG VPS35L PLA2G4A CC2D2A AP4B1

4.80e-052001247M5815
CoexpressionGSE25890_CTRL_VS_IL33_IL7_TREATED_NUOCYTES_UP

ARHGAP10 LRCH3 SNX7 RIN2 CLNS1A SVIL HERC2

4.80e-052001247M7358
CoexpressionLAKE_ADULT_KIDNEY_C22_ENDOTHELIAL_CELLS_GLOMERULAR_CAPILLARIES

SYNE1 ARHGAP26 ITGA1 PTPRG SVIL UTRN

4.92e-051371246M39241
CoexpressionOISHI_CHOLANGIOMA_STEM_CELL_LIKE_DN

TMC7 ARHGAP10 SEPTIN9 ARHGAP26 SEMA3A PTK2B RIN2 MX2

4.98e-052741248M289
CoexpressionGAUTAM_EYE_IRIS_CILIARY_BODY_CILIARY_BODY_ENDOTHELIAL_CELLS

FAT4 ACVR2B IFNAR2 SEMA3A PPP6C PCDH11X PPP2R3C CDH2 GNPAT

5.12e-053561249M43609
CoexpressionLAKE_ADULT_KIDNEY_C28_INTERSTITIUM

ARHGAP10 SYNE1 ITGA1 DST UTRN

5.60e-05861245M39247
CoexpressionLAKE_ADULT_KIDNEY_C29_UNKNOWN_NOVEL_PT_CFH_POS_SUBPOPULATION_S2

SYNE1 NEDD9 DST SVIL UTRN

5.60e-05861245M39248
CoexpressionJIANG_TIP30_TARGETS_UP

PSMC6 NEDD9 EEF2 CDH2

6.68e-05461244M12641
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HENDO

TES VWF TMC7 ITGA1 MYO5C NRP1 ITPR3 NEDD9 TBC1D4 PTPRG SVIL GPCPD1 MCF2L UTRN

8.16e-0588812414M39049
CoexpressionBOQUEST_STEM_CELL_DN

VWF WARS1 CHD7 MYO5C NEDD9 DNM3 MCF2L

8.26e-052181247M1578
CoexpressionREN_ALVEOLAR_RHABDOMYOSARCOMA_UP

VWF CHD7 RYR1 SYNE2 RASSF4

1.10e-04991245M768
CoexpressionMARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN

EPRS1 POLE3 RCC2 ACTR2 POLR3C PTPRG MLLT1 CDH2 UTRN HDLBP

1.85e-0451912410M3395
CoexpressionLAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2

ARHGAP26 NRP1 PTPRG SVIL SYNE2 VPS13A

1.95e-041761246M39223
CoexpressionGSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_UP

EPC2 CHD7 RRM2 DST MKI67 MX2

1.95e-041761246M2981
CoexpressionLAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS

SYNE1 ITGA1 DST PTPRG ARID5B UTRN

2.01e-041771246M39245
CoexpressionCHEOK_RESPONSE_TO_MERCAPTOPURINE_AND_HD_MTX_UP

POLR3C PTPRG

2.20e-0451242M5076
CoexpressionDAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP

WARS1 ARHGAP26 CHD7 DST SYNE2 HERC2 RASSF4 IQCG

2.21e-043401248M2012
CoexpressionGSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP

SYNE1 PPWD1 EEF2 HERC2 UTRN GNPAT

2.48e-041841246M9005
CoexpressionFIGUEROA_AML_METHYLATION_CLUSTER_7_UP

VWF HNRNPD IFNAR2 MORF4L1 DNM3

2.50e-041181245M2179
CoexpressionMARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN

EPRS1 POLE3 RCC2 ACTR2 POLR3C PTPRG MLLT1 CDH2 UTRN HDLBP

2.65e-0454312410MM997
CoexpressionHOUNKPE_HOUSEKEEPING_GENES

NELFB ARFGEF2 POLE3 COG3 HNRNPD ACTR2 POLR3C PPP6C MTOR MORF4L1 CLNS1A HMGXB3 EIF3A GNPAT HDLBP

2.93e-04112912415M42508
CoexpressionMURARO_PANCREAS_ENDOTHELIAL_CELL

VWF ITGA1 RCC2 NRP1 NEDD9 MLLT1 MCF2L UTRN

3.36e-043621248M39176
CoexpressionCASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN

EPRS1 VWF WARS1 RRM2 HNRNPD ACTR2 TBC1D4 ARID5B MKI67 PLA2G4A POLQ

3.44e-0466912411M18635
CoexpressionGSE13485_DAY1_VS_DAY7_YF17D_VACCINE_PBMC_DN

WARS1 CASP5 RRM2 RIN2 PPP2R3C MX2

3.67e-041981246M3296
CoexpressionGSE360_CTRL_VS_B_MALAYI_LOW_DOSE_DC_UP

MYOZ2 CASP5 RRM2 TBC1D4 DNM3 EIF3A

3.67e-041981246M5152
CoexpressionGSE3982_BASOPHIL_VS_NKCELL_DN

RASGRF1 SEPTIN9 SYNE1 PCDHGA1 MYO5C CLNS1A

3.67e-041981246M5563
CoexpressionGSE45365_WT_VS_IFNAR_KO_CD8A_DC_DN

WARS1 CASP5 BRAP RIN2 RASSF4 TP53BP2

3.77e-041991246M9963
CoexpressionGSE5589_WT_VS_IL6_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN

SEPTIN9 RHOBTB3 NEDD9 SYNE2 EIF3A CDH2

3.77e-041991246M6646
CoexpressionGSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_DN

SEPTIN9 SYNE1 ACTR2 SVIL CDH2 GNPAT

3.77e-041991246M5201
CoexpressionGSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_MAC_UP

DMXL2 ACTR2 ORC4 MKI67 EIF3A TP53BP2

3.77e-041991246M5239
CoexpressionGSE10325_CD4_TCELL_VS_LUPUS_CD4_TCELL_DN

WARS1 HERC2P3 HNRNPD ARID5B UAP1L1 MX2

3.77e-041991246M3093
CoexpressionGSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_DN

CFAP43 TEX15 PPWD1 NRP1 ABCC12 CDH2

3.77e-041991246M4328
CoexpressionCHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN

FAT4 WASHC4 DHX33 ITGA1 ACTR2 NRP1 SEMA3A PTPRG SNX7

3.78e-044651249M9192
CoexpressionHOUNKPE_HOUSEKEEPING_GENES

NELFB ARFGEF2 POLE3 COG3 HNRNPD ACTR2 POLR3C PPP6C MTOR MORF4L1 CLNS1A HMGXB3 EIF3A GNPAT HDLBP

3.83e-04115812415MM1338
CoexpressionGSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_DN

ATP13A1 CASP5 RIN2 MKI67 UTRN MX2

3.88e-042001246M3288
CoexpressionGSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_DN

SYNE1 HERC2P3 SYNE2 DNM3 EIF3A MCF2L

3.88e-042001246M8306
CoexpressionGSE1432_CTRL_VS_IFNG_24H_MICROGLIA_DN

WARS1 RHOBTB3 CASP5 POLR3C PLA2G4A MX2

3.88e-042001246M3408
CoexpressionGSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_UP

VIPR1 PPWD1 TBC1D4 SVIL ARID5B MX2

3.88e-042001246M9883
CoexpressionGSE17721_LPS_VS_CPG_2H_BMDC_UP

ARHGAP10 NEDD9 ESYT3 SVIL AP4B1 MX2

3.88e-042001246M3989
CoexpressionGSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_DN

NELFB CHD7 POLR3C PTK2B SYNE2 CDH2

3.88e-042001246M6372
CoexpressionGSE25123_WT_VS_PPARG_KO_MACROPHAGE_ROSIGLITAZONE_STIM_UP

RASGRF1 RHOBTB3 RYR1 NRP1 TBC1D4 DST

3.88e-042001246M7978
CoexpressionGSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_DN

DMXL2 SEPTIN9 CAMSAP3 NEDD9 CLNS1A SYNE2

3.88e-042001246M6617
CoexpressionHALLMARK_MTORC1_SIGNALING

EPRS1 TES WARS1 PSMC6 RRM2 ACTR2

3.88e-042001246M5924
CoexpressionMURARO_PANCREAS_MESENCHYMAL_STROMAL_CELL

EPRS1 WARS1 ITGA1 PTGFRN RCC2 NRP1 EEF2 SVIL ARID5B EIF3A HDLBP

3.99e-0468112411M39175
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_1000

SEPTIN9 RHOBTB3 ARHGAP26 CAMSAP3 CHD7 TEX15 IFNAR2 SEMA3A NEDD9 PTK2B TBC1D4 DST PTPRG RIN2 PCDH11X PLA2G4A CDH2 UTRN

1.78e-0683712418gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_1000
CoexpressionAtlasdev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000

FAT4 ARHGAP26 CAMSAP3 CHD7 TEX15 IFNAR2 SEMA3A TBC1D4 DST PTPRG RIN2 PCDH11X GPCPD1 PLA2G4A CDH2 UTRN

1.81e-0580312416gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_1000
ToppCellLV-09._Endothelium_I|World / Chamber and Cluster_Paper

VWF WARS1 SYNE1 ITGA1 NEDD9 SLC9C1 RIN2 SYNE2 DNM3 MCF2L UTRN

9.20e-121951251119e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

VWF WARS1 SYNE1 ITGA1 NRP1 NEDD9 SLC9C1 RIN2 SYNE2 MCF2L UTRN

9.20e-121951251150a193475db1bb1e05b8590225a553688c372c14
ToppCellLV-09._Endothelium_I|LV / Chamber and Cluster_Paper

VWF WARS1 SYNE1 ITGA1 NEDD9 SLC9C1 RIN2 SYNE2 DNM3 MCF2L UTRN

1.03e-1119712511f9731d4d636e51b94a96805eee6afe9aedc175e3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP10 SYNE1 ARHGAP26 RGS9 NEDD9 TBC1D4 DNAH17 DNM3 CDH2 UTRN

7.80e-1117612510327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellCOVID-19-Heart-EC_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

VWF SYNE1 ITGA1 NRP1 NEDD9 SLC9C1 PTPRG RIN2 SYNE2 MCF2L

1.57e-1018912510fe49852ba15f948b384d6b4c258927c70b741357
ToppCellRV-09._Endothelium_I|World / Chamber and Cluster_Paper

VWF WARS1 SYNE1 ITGA1 NEDD9 SLC9C1 RIN2 SYNE2 MCF2L UTRN

1.93e-1019312510e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCellRA-09._Endothelium_I|RA / Chamber and Cluster_Paper

VWF WARS1 SYNE1 ITGA1 NEDD9 RIN2 SYNE2 MCF2L UTRN

3.88e-0919212598a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCellRV-09._Endothelium_I|RV / Chamber and Cluster_Paper

VWF WARS1 SYNE1 ITGA1 NEDD9 RIN2 SYNE2 MCF2L UTRN

4.25e-0919412597b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCellLA-09._Endothelium_I|World / Chamber and Cluster_Paper

VWF WARS1 SYNE1 ITGA1 NEDD9 SLC9C1 RIN2 SYNE2 MCF2L

4.45e-091951259fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

VWF WARS1 SYNE1 ITGA1 NEDD9 SLC9C1 RIN2 SYNE2 MCF2L

4.86e-091971259ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FAT4 VWF CHD7 NRP1 DST PTPRG SYNE2 MCF2L UTRN

5.55e-092001259dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP10 SYNE1 NEDD9 TBC1D4 DNAH17 DNM3 CDH2 UTRN

3.89e-081771258da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

VIPR1 VWF SYNE1 ITGA1 NRP1 PTPRG RIN2 MCF2L

6.73e-0819012587f3f419fffe02934b6f27b697f7a6401072491ed
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

VWF ARHGAP26 ITGA1 NRP1 NEDD9 SYNE2 MCF2L UTRN

6.73e-081901258a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

VWF WARS1 SYNE1 ITGA1 NEDD9 RIN2 SYNE2 MCF2L

7.01e-081911258c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

VIPR1 FAT4 VWF SYNE1 ITGA1 PTPRG RIN2 MCF2L

7.90e-08194125840842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCellCOVID-19-lung-Capillary_Aerocytes|COVID-19 / Disease (COVID-19 only), tissue and cell type

VIPR1 WARS1 SYNE1 RGS9 ITGA1 SEMA3A NEDD9 SYNE2

8.55e-08196125849cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCellControl-Control-Myeloid-immature_Neutrophil|Control / Disease, condition lineage and cell class

DMXL2 DNAH10 ARFGEF2 CHD7 VPS13A MKI67 POLQ HDLBP

9.99e-082001258118321ac443feb42aee171baccfc4610f00a8822
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FAT4 VWF NRP1 DST PTPRG SYNE2 MCF2L UTRN

9.99e-082001258a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 RGS9 RCC2 NEDD9 ABCB9 MLLT1 MCF2L

7.82e-07180125712f3c4c4aa7fe03c0ef847bd4d4942c808015f5f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 RGS9 RCC2 NEDD9 ABCB9 MLLT1 MCF2L

7.82e-0718012571bc01bb76d0d3f8db74f9244436d3e6d6015ed5d
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 RGS9 RCC2 NEDD9 ABCB9 MLLT1 MCF2L

7.82e-0718012572a28fbfe10a340c8662c2c8be33792f41fc09088
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP26 RGS9 NRP1 NEDD9 ASB18 TBC1D4 CDH2

8.42e-0718212575e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DMXL2 DNAH10 CHD7 VPS13A MKI67 POLQ HDLBP

9.06e-071841257a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DMXL2 DNAH10 CHD7 VPS13A MKI67 POLQ HDLBP

9.06e-071841257081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

DMXL2 DNAH10 CHD7 VPS13A MKI67 POLQ HDLBP

9.06e-07184125745f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DMXL2 DNAH10 CHD7 VPS13A MKI67 POLQ HDLBP

9.06e-07184125784c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DMXL2 DNAH10 CHD7 VPS13A MKI67 POLQ HDLBP

9.06e-071841257d31d4116d1d196633784863781fa45673607a421
ToppCellMyeloid-B_(Activated_Macrophage)|World / shred on cell class and cell subclass (v4)

DMXL2 SEPTIN9 ACTR2 RRAGC DST EIF3A RASSF4

9.74e-07186125733d731a7883d75e4e7db83b641cdb1e9a39938bf
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

ARHGAP26 ITGA1 SYNE2 GPCPD1 CENATAC UTRN TP53BP2

1.05e-061881257ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 ARHGAP26 NEDD9 TBC1D4 DNM3 CDH2 UTRN

1.05e-06188125763a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

VIPR1 FAT4 SYNE1 ARHGAP26 RGS9 ITGA1 RIN2

1.16e-061911257f229abf69a1217194f74b0502486907e07dba989
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 ARHGAP26 TBC1D4 PTPRG RIN2 EIF3A HERC2

1.20e-0619212571ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 VWF NRP1 IFNAR2 NEDD9 GPCPD1 MCF2L

1.25e-061931257e1d546165dcc2392f540162206852c4717d7306f
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

VWF ARHGAP26 ITGA1 NEDD9 RIN2 SYNE2 PCDH11X

1.25e-0619312572531266bc57339d4e2b22a88817008e32b8c1598
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 ARHGAP26 ITPR3 TBC1D4 SVIL SYNE2 DNM3

1.29e-061941257e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

VIPR1 FAT4 VWF ITGA1 PTPRG RIN2 MCF2L

1.29e-06194125768004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 SYNE1 CFAP43 RRM2 PTPRG SYNE2 MKI67

1.38e-061961257af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 SYNE1 CFAP43 RRM2 PTPRG SYNE2 MKI67

1.38e-0619612576d02d494196e3f857d53eea46d9419690d43beca
ToppCellCOPD-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

VIPR1 VWF WARS1 ITGA1 PTPRG RIN2 MCF2L

1.43e-06197125730dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CAMSAP3 CHD7 MYO5C SYNE2 PCDH11X C5 UTRN

1.43e-0619712573d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 VWF WARS1 ITGA1 NRP1 NEDD9 SYNE2

1.48e-061981257d5990cab01de6e6f3757f5a50ef70ced711bb1fa
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Vein|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

VWF SEPTIN9 NRP1 DST PTPRG SYNE2 MCF2L

1.58e-0620012577eb366b2c5394af7c77650bde6261e7dac67154e
ToppCellControl_saline-Endothelial-Endothelial-Gen_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

FAT4 VWF NEDD9 DST PTPRG GPCPD1 MCF2L

1.58e-0620012573b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

VIPR1 ARHGAP26 RGS9 ITGA1 SYNE2 PCDH11X

2.71e-0613912562fdc8f36510aff24abbc79ef2a842db75a85f946
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

VIPR1 ARHGAP26 RGS9 ITGA1 SYNE2 PCDH11X

2.71e-0613912565970a654c64e3b54f9d18c102f5b125eec892fc5
ToppCellfacs-Lung-3m-Hematologic-myeloid-non-classical_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEPTIN9 RYR1 PTK2B MKI67 GPCPD1 RASSF4

6.77e-061631256bbbc3f0ce2616d07136f69ce682ba1d3790711d9
ToppCellfacs-Lung-3m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEPTIN9 RYR1 PTK2B MKI67 GPCPD1 RASSF4

7.02e-06164125611dfd84f5fb90de330858e1e852848832734e004
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHD7 ITGA1 TMEM132B DST RASSF4 CDH2

8.05e-061681256af82e07d1eec51fc6530155f37addbce6221885d
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CUX2 ARFGEF2 MKI67 RASSF4 POLQ ZNF471

8.91e-06171125641932c9e70829ee3d55ca5fdb74d290fc8229416
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TES ITGA1 NRP1 SLC9C1 ZNF561 RASSF4

8.91e-061711256285533ca2a6a411773313166bee35542f34d1a3c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH10 DHX33 MKI67 ZNF561 C5 AP4B1

9.52e-061731256506efcaa5afd6ed5e565c4c4def6a4505fea97c5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP26 CFAP43 NRP1 NEDD9 ASB18 CDH2

1.02e-051751256284fdc7a9d303636a637041846850d19d114861a
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DMXL2 SEPTIN9 RRM2 RRAGC MKI67 EIF3A

1.05e-051761256270d7908dbd84028958d257f94941dc685e20255
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA1 NEDD9 PTPRG ARID5B MCF2L POLQ

1.12e-051781256ba2f0585626988b511046630bc16be5c5fec3fb2
ToppCell343B-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

RRM2 MKI67 CCDC15 PLA2G4A MCF2L POLQ

1.12e-051781256c7e890cd02206c516cf1d7692ea7abc8ce746482
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

ARHGAP10 SYNE1 ITGA1 NRP1 DST CDH2

1.16e-051791256e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

VIPR1 ARHGAP26 ITGA1 SEMA3A RIN2 PCDH11X

1.19e-051801256b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac|lymph-node_spleen / Manually curated celltypes from each tissue

DMXL2 RRM2 NRP1 MKI67 PLA2G4A RASSF4

1.19e-0518012564eea8366cdb82c356325ce88f09ad8b302c17a07
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHD7 ITGA1 TMEM132B DST RASSF4 CDH2

1.23e-051811256a436e7e4c36403257ea90160a58ca0d6d7c0cdfc
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(other)|COVID-19 / group, cell type (main and fine annotations)

VIPR1 VWF ITGA1 PTPRG SYNE2 MCF2L

1.23e-05181125626eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

VIPR1 SYNE1 ITGA1 SEMA3A SYNE2 PCDH11X

1.23e-051811256c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

NRP1 SEMA3A NEDD9 PTPRG GPCPD1 CDH2

1.27e-0518212567b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPRS1 VWF IFNAR2 SLC9C1 EIF3A TP53BP2

1.35e-051841256c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

MYOZ2 ASB18 TBC1D4 DST SVIL CDH2

1.35e-051841256ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCelldroplet-Lung-LUNG-1m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 SEPTIN9 ACTR2 PTK2B GPCPD1 RASSF4

1.39e-05185125653a5218c1e6eb12daccde3d6e02f337e2586d74c
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DMXL2 SEPTIN9 RRAGC DST EIF3A RASSF4

1.44e-0518612567950e03ea080238c168b9d807e217f459acdfb28
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 VWF WARS1 ITGA1 PTPRG MCF2L

1.53e-051881256117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCell10x5'-GI_large-bowel-Myeloid_Monocytic|GI_large-bowel / Manually curated celltypes from each tissue

DMXL2 ZNF285 NRP1 RIN2 PLA2G4A CC2D2A

1.53e-051881256d0045fdda757d191dabc7853f6a6e99c0e97d93d
ToppCell10x5'-GI_large-bowel-Myeloid_Monocytic-Classical_monocytes|GI_large-bowel / Manually curated celltypes from each tissue

DMXL2 ZNF285 NRP1 RIN2 PLA2G4A CC2D2A

1.53e-0518812560bcf04aa47738f43c1a87dae5dc487738ee86f8c
ToppCellControl-Endothelial_cells|Control / group, cell type (main and fine annotations)

VIPR1 VWF ARHGAP26 PTPRG RIN2 MCF2L

1.53e-0518812563953b08abfea93468fc8d177bdb16ca7c6ffa1ab
ToppCellCOPD-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

WARS1 HERC2P3 NEDD9 PTK2B UTRN MX2

1.62e-051901256aece860b5609ad5a8fc920d685f0d0ec71bf9018
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH3 DNAH10 SYNE1 CFAP43 CC2D2A IQCG

1.62e-0519012569ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH3 DNAH10 SYNE1 CFAP43 CC2D2A IQCG

1.62e-051901256833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

VIPR1 FAT4 SYNE1 ARHGAP26 ITGA1 RIN2

1.62e-0519012560e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

VIPR1 SYNE1 RGS9 ITGA1 SEMA3A RIN2

1.62e-0519012560a351609a72fd638c84b2435782e312ee6a33aac
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-filiform|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR1 NRP1 ESYT3 SNX7 SYNE2 RASSF4

1.62e-0519012568a53f4d3c9aca45b5826f53f7dcdfb8bc8280acb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP43 NEDD9 TBC1D4 SYNE2 DNM3 CDH2

1.67e-051911256d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellControl-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

VIPR1 FAT4 VWF SYNE1 ITGA1 PTPRG

1.67e-051911256c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCellControl-Endothelial-VE_Capillary_B|Control / Disease state, Lineage and Cell class

VIPR1 FAT4 VWF SYNE1 ITGA1 PTPRG

1.67e-051911256322237793a1278bafb14e63cab688b353e352dcc
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRP1 TBC1D4 PTPRG GPCPD1 MCF2L UTRN

1.72e-0519212569ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRP1 TBC1D4 PTPRG GPCPD1 MCF2L UTRN

1.72e-051921256a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRP1 TBC1D4 PTPRG GPCPD1 MCF2L UTRN

1.72e-05192125666defad13bd8e79319741e43ddb056841710b1d7
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

VIPR1 VWF ITGA1 PTPRG RIN2 MCF2L

1.77e-051931256f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

VWF ARHGAP26 ITGA1 NEDD9 RIN2 PCDH11X

1.77e-05193125601c2df9206f1527c578e808978e58196c35e72f5
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 VWF NRP1 IFNAR2 NEDD9 MCF2L

1.77e-051931256aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 VWF NRP1 IFNAR2 NEDD9 MCF2L

1.77e-051931256c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellIPF-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

VIPR1 FAT4 VWF ITGA1 PTPRG MCF2L

1.77e-051931256d7750a7575ef257963b7f1c64fa67c52dbff797b
ToppCellCOPD-Myeloid-ncMonocyte|COPD / Disease state, Lineage and Cell class

WARS1 HERC2P3 NEDD9 PTK2B UTRN MX2

1.77e-051931256936ca95995599356b794fba32bfd82d8de339365
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

VIPR1 VWF ITGA1 PTPRG RIN2 MCF2L

1.77e-051931256ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)|Children_(3_yrs) / Lineage, Cell type, age group and donor

VIPR1 FAT4 VWF ITGA1 PTPRG MCF2L

1.82e-05194125671ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-Plasma_cell|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EPRS1 RRM2 IFNAR2 ABCB9 MKI67 HDLBP

1.82e-051941256297286c57d7ee6338d9cf77b27eb2809378ce15d
ToppCellfacs-Heart-LA-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF ITGA1 NRP1 PTPRG MCF2L UTRN

1.82e-05194125633cc4f1d716cb71d54cdedbe9bbdc0d7b17c4777
ToppCellCOPD-Endothelial-VE_Capillary_B|COPD / Disease state, Lineage and Cell class

VIPR1 VWF ITGA1 PTPRG RIN2 MCF2L

1.82e-05194125618b7f901c12ca4f21f9a1eafd092aefe4d668b6d
ToppCellMonocytes-Inflammatory_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

DMXL2 WARS1 SEPTIN9 CASP5 NEDD9 SVIL

1.82e-05194125628d19105123b015f8aa25ea8e6c078f630d4ba80
ToppCell367C-Endothelial_cells-Endothelial-E-|367C / Donor, Lineage, Cell class and subclass (all cells)

VIPR1 VWF ITGA1 NEDD9 PTPRG MCF2L

1.88e-05195125665fc50e3818e902028fc4226070fa57609c66b9c
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

MYOZ2 ASB18 TBC1D4 DST SVIL CDH2

1.88e-05195125675fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell367C-Endothelial_cells-Endothelial-E|367C / Donor, Lineage, Cell class and subclass (all cells)

VIPR1 VWF ITGA1 NEDD9 PTPRG MCF2L

1.88e-0519512563b79e6bb525b17192ecec9e1227a29c419968144
ToppCellControl-Classical_Monocyte-cMono_2|Control / Disease condition and Cell class

DMXL2 WASHC4 ARHGAP26 GPCPD1 EIF3A RASSF4

1.88e-0519512560fea64ee3eedf3929abb0dd9c5f5fc72f181eed9
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 DNAH10 SYNE1 CFAP43 CC2D2A IQCG

1.88e-0519512563486eae5fdb062a75a907b896c9d7b396d2aa195
DrugGSK-3 Inhibitor IX; Down 200; 0.5uM; PC3; HT_HG-U133A

DNAH3 FAT4 WARS1 NEDD9 ORC4 ABCB9 ARID5B VPS13A HDLBP

1.31e-0619612496585_DN
DrugYohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; MCF7; HT_HG-U133A

DMXL2 TMC7 SEPTIN9 ARHGAP26 NEDD9 TBC1D4 ABCB9 MTOR RIN2

1.31e-0619612492755_DN
Drug0297417-0002B [362658-29-5]; Up 200; 10uM; MCF7; HT_HG-U133A

SEPTIN9 ACVR2B NEDD9 ABCB9 RIN2 SVIL MCF2L HDLBP

8.71e-0618712486902_UP
DiseaseMalignant neoplasm of breast

VWF WARS1 SYNE1 ARFGEF2 COG3 HNRNPL SEMA3A EEF2 MTOR SYNE2 MKI67 PLA2G4A HERC2 CDH2 TP53BP2 HDLBP

1.04e-05107412316C0006142
Diseasetestosterone measurement

CUX2 WARS1 ARHGAP10 SEPTIN9 ARHGAP26 CHD7 IFNAR2 UGT1A4 SEMA3A NEDD9 PTPRG RIN2 SYNE2 ARID5B DNM3 UTRN ZNF654

2.26e-05127512317EFO_0004908
DiseaseHeterotopia, Periventricular, Autosomal Recessive

FAT4 ARFGEF2

5.16e-0531232C1842563
DiseaseX-linked mental retardation with cerebellar hypoplasia and distinctive facial appearance (implicated_via_orthology)

ARHGAP10 ARHGAP26

1.03e-0441232DOID:0080311 (implicated_via_orthology)
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE1 SYNE2

1.03e-0441232cv:CN293514
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

1.71e-0451232C1450051
Diseaseinterstitial cystitis (is_marker_for)

MTOR MKI67

1.71e-0451232DOID:13949 (is_marker_for)
Diseasecentronuclear myopathy 1 (implicated_via_orthology)

DNM3 MX2

1.71e-0451232DOID:0111223 (implicated_via_orthology)
Diseasemicrocytic anemia (implicated_via_orthology)

DNM3 MX2

1.71e-0451232DOID:11252 (implicated_via_orthology)
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE1 SYNE2

1.71e-0451232C0410190
DiseaseCharcot-Marie-Tooth disease dominant intermediate B (implicated_via_orthology)

DNM3 MX2

1.71e-0451232DOID:0110197 (implicated_via_orthology)
DiseaseEmery-Dreifuss muscular dystrophy

SYNE1 SYNE2

2.56e-0461232cv:C0410189
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE1 SYNE2

2.56e-0461232C0410189
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

3.57e-0471232C0751337
DiseaseBreast Carcinoma

SYNE1 HNRNPL EEF2 MTOR MKI67 PLA2G4A HERC2 CDH2 TP53BP2

4.36e-045381239C0678222
Diseaseliver fibrosis measurement

VWF BRAP ITPR3 DNM3

4.69e-04861234EFO_0010576
Diseasemelanoma

FAT4 TMEM132B PTK2B PPP6C CLNS1A MX2

6.21e-042481236C0025202
Diseaseepilepsy

CUX2 BRAP PLA2G4A

6.71e-04411233EFO_0000474
Diseasesmall vessel stroke

FAT4 ARHGAP26 BRAP PLA2G4A

7.10e-04961234EFO_1001504
DiseaseTetralogy of Fallot

BRAP NRP1

7.59e-04101232HP_0001636
DiseaseAsthma, Occupational

PLA2G4A HERC2

7.59e-04101232C0264423
Diseasenon-high density lipoprotein cholesterol measurement

DNAH10 ARFGEF2 CHD7 ITGA1 ZNF285 UGT1A4 SYNE2 DNM3 GPCPD1 ZNF471

8.26e-0471312310EFO_0005689
DiseaseHypermetropia

RASGRF1 ARHGAP10 SEPTIN9 CHD7

9.25e-041031234HP_0000540
Diseaseexecutive function measurement

DMXL2 ARFGEF2 RCC2 RYR1 LRCH3 MYO5C NEDD9

1.03e-033761237EFO_0009332
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE1 SYNE2

1.11e-03121232DOID:11726 (implicated_via_orthology)
Diseaseblood copper measurement

CUX2 BRAP ITPR3

1.20e-03501233EFO_0007578
Diseasedevelopmental and epileptic encephalopathy (implicated_via_orthology)

DNM3 MX2

1.30e-03131232DOID:0112202 (implicated_via_orthology)
Diseaseintraocular pressure measurement

TES SEPTIN9 BRAP MTOR OR4A16 ARID5B HERC2 HDLBP

1.35e-035091238EFO_0004695
Diseasereticulocyte count

EPRS1 VWF DNAH10 SEPTIN9 RHOBTB3 RGS9 ITGA1 BRAP NRP1 DNAH17 SYNE2 VPS13A

1.43e-03104512312EFO_0007986
DiseaseCarcinoma, Granular Cell

FAT4 EEF2 MTOR MKI67

1.44e-031161234C0205644
DiseaseAdenocarcinoma, Tubular

FAT4 EEF2 MTOR MKI67

1.44e-031161234C0205645
DiseaseAdenocarcinoma, Oxyphilic

FAT4 EEF2 MTOR MKI67

1.44e-031161234C0205642
DiseaseCarcinoma, Cribriform

FAT4 EEF2 MTOR MKI67

1.44e-031161234C0205643
DiseaseAdenocarcinoma, Basal Cell

FAT4 EEF2 MTOR MKI67

1.44e-031161234C0205641
DiseaseAdenocarcinoma

FAT4 EEF2 MTOR MKI67

1.44e-031161234C0001418
Diseaseurinary bladder cancer (biomarker_via_orthology)

RRM2 MKI67

1.52e-03141232DOID:11054 (biomarker_via_orthology)
Diseasereticulocyte measurement

VWF DNAH10 SEPTIN9 RHOBTB3 MYOZ2 ARFGEF2 RGS9 ITGA1 BRAP DNAH17 SYNE2 VPS13A

1.52e-03105312312EFO_0010700
Diseaseimmature platelet measurement

VWF RTTN SVIL DNM3

1.58e-031191234EFO_0803541
DiseaseMammary Carcinoma, Human

SYNE1 HNRNPL EEF2 MTOR MKI67 PLA2G4A CDH2 TP53BP2

1.64e-035251238C4704874
DiseaseMammary Neoplasms, Human

SYNE1 HNRNPL EEF2 MTOR MKI67 PLA2G4A CDH2 TP53BP2

1.64e-035251238C1257931
DiseaseMammary Neoplasms

SYNE1 HNRNPL EEF2 MTOR MKI67 PLA2G4A CDH2 TP53BP2

1.68e-035271238C1458155
DiseaseDyskinesia, Medication-Induced

RASGRF1 RGS9

1.75e-03151232C0751088
DiseaseDyskinesia, Drug-Induced

RASGRF1 RGS9

1.75e-03151232C0013386
Diseaseresponse to beta blocker, heart rate

EPC2 NRP1 DNAH17

1.76e-03571233EFO_0004326, EFO_0007766
Diseasewaist-hip ratio

DMXL2 CUX2 DNAH10 MYOZ2 NRP1 NEDD9 PTPRG ABCB9 DNAH17 SYNE2 ARID5B DNM3 GPCPD1

1.84e-03122612313EFO_0004343
DiseaseSarcomatoid Renal Cell Carcinoma

RYR1 EEF2 MTOR SYNE2

2.06e-031281234C1266043
DiseaseChromophobe Renal Cell Carcinoma

RYR1 EEF2 MTOR SYNE2

2.06e-031281234C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

RYR1 EEF2 MTOR SYNE2

2.06e-031281234C1266044
DiseasePapillary Renal Cell Carcinoma

RYR1 EEF2 MTOR SYNE2

2.06e-031281234C1306837
DiseaseRenal Cell Carcinoma

RYR1 EEF2 MTOR SYNE2

2.06e-031281234C0007134
Diseasemethadone dose measurement

TEX15 SNX7 UTRN

2.23e-03621233EFO_0007907
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

DNAH10 UGT1A4

2.25e-03171232EFO_0004611, EFO_0007800
Diseasepolycystic kidney disease (biomarker_via_orthology)

MTOR PLA2G4A

2.81e-03191232DOID:0080322 (biomarker_via_orthology)
Diseasecoagulation factor measurement

VWF MCF2L

3.12e-03201232EFO_0004634
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

RYR1 EEF2 MTOR SYNE2

3.48e-031481234C0279702
Diseasemean platelet volume

VWF PCDHGA1 RTTN CHD7 RCC2 TBC1D4 OR4A16 SVIL SYNE2 DNM3 MCF2L

3.64e-03102012311EFO_0004584
Diseaseeosinophil count

DNAH3 CUX2 ARHGAP26 CHD7 PTGFRN BRAP ITPR3 IFNAR2 PTK2B EPS15L1 SLC9C1 TBC1D4 DNAJC5B HDLBP

3.68e-03148812314EFO_0004842
DiseaseImmunologic Deficiency Syndromes

CHD7 C5

4.12e-03231232C0021051

Protein segments in the cluster

PeptideGeneStartEntry
IPDDMEAIPVKQFVK

PTPRG

821

P23470
DETFEFFVPMEEVKK

ESYT3

821

A0FGR9
FFVPMEEVKKRSLDV

ESYT3

826

A0FGR9
VPVADKMRFDEIFLK

EPS15L1

271

Q9UBC2
AQQVFREKKESMVIP

EPC2

61

Q52LR7
DLMKFVAPFNEVIEQ

BRAP

176

Q7Z569
ENFPMKARTVEELKE

CFAP43

906

Q8NDM7
FVMVAKTVPDDAKQL

NEDD9

531

Q14511
KAEMVVPDFSELFKE

ATP13A1

226

Q9HD20
KADFPKVRAKEQTFM

FAT4

2561

Q6V0I7
KMQIEVFFKEIFLNI

ARFGEF2

471

Q9Y6D5
VENVKSETFPAVKME

AP4B1

461

Q9Y6B7
EDMEKKETEIFFQPS

DMXL2

866

Q8TDJ6
EFKKNVPEEIREMVA

CUX2

51

O14529
QIKSDMEKDVDFPVF

DNAJC5B

161

Q9UF47
FMCFEVLKPDFVQVK

CAMSAP3

311

Q9P1Y5
QAKIEEFEKLMSREP

CHD7

926

Q9P2D1
EKKVRPFSMFDAVDQ

TP53BP2

451

Q13625
PTKNREKIVEVMFET

ACTR2

116

P61160
KEDAVEQFMFQIKTL

CCDC83

36

Q8IWF9
VEFNKMQDLVFKKPT

IQCG

141

Q9H095
EQKDEMVPRLVKLFD

RCC2

366

Q9P258
FEMPVLDSFVEKLKE

RASSF4

276

Q9H2L5
SKRVANFFQIKMDVP

RGS9

626

O75916
LSVFKKEFVEVFPMQ

ITPR3

991

Q14573
ITAPEMLIDFFVERK

OR4M2B

76

A0A0X1KG70
EETFMNRVEVKVKIP

MORF4L1

186

Q9UBU8
SFQDVKDEIFDMVKP

PPP2R3C

386

Q969Q6
NFEKPVVMKAFEHLQ

ORC4

366

O43929
QEIQERKKFEFVEPM

ARHGAP10

186

A1A4S6
VKPVAIREFQKTEDM

LRCH3

421

Q96II8
KKPRELMNFKSFVEE

LEXM

256

Q3ZCV2
VNDFDLMKFEVKKEP

MAFA

21

Q8NHW3
EFALKEEPVDVEKMR

HERC2

1641

O95714
LNMFKVFQKEEIEPL

DST

5321

Q03001
KEVIPEEVFQMHKPF

ASB18

396

Q6ZVZ8
KEIVFKFMVKFFPVD

FRMD7

71

Q6ZUT3
ENREIMKPFFISKQS

FSIP2

3351

Q5CZC0
IFPAKFLEDVITEMV

FSIP2

5781

Q5CZC0
PFEIVKMEFNEKELR

DNM3

371

Q9UQ16
RTSQVKVVEVKPDMF

HMGXB3

586

Q12766
TQDPDVKKTLFVMFL

OR4A16

16

Q8NH70
ITAPEMLIDFFVERK

OR4M2

76

Q8NGB6
DSQVFKEPKMEVELI

NELFB

356

Q8WX92
MEFQRFVTPLKEALE

POLE3

76

Q9NRF9
EMKEIERPFETYKEN

MKI67

921

P46013
MLFIKVKDENDNAPV

PCDH11X

451

Q9BZA7
DVAVVKVTMNFEPNK

ITGA1

666

P56199
MVKFPSIVEEELQFD

IFNAR2

151

P48551
IVFVPKMSEIILEFE

NRP1

176

O14786
VVFDCIMELKDPNVK

IGSF22

251

Q8N9C0
VLEEAQRKNPMFKFE

CBLIF

346

P27352
MVNAKFEEESKEPVA

CLNS1A

81

P54105
MKKKFDADPVELFEI

GPCPD1

381

Q9NPB8
LMEIFRKVQKSFEVP

CASP5

396

P51878
MNPREEKVKIITEEF

CC2D2A

1

Q9P2K1
NIVMEPFFKREVFDT

GNPAT

261

O15228
KVKERQAATDNMFEP

DNAH17

1131

Q9UFH2
NIFPADEKADIVEKM

DNAH3

2516

Q8TD57
PDFIMAKQVEQLEKE

EIF3A

666

Q14152
EQVLPQLEAFMKDKE

C7orf25

286

Q9BPX7
KLFVEQLEEFMTKVS

COG3

706

Q96JB2
KENLQDVFRKVEMPS

POLQ

2066

O75417
KAKVFKDVFLEMNIP

C5

816

P01031
DEFEKFDKMTVPEIQ

DHX33

421

Q9H6R0
FKFNRDDFKMKVPVI

MCF2L

181

O15068
VVVMPKKRQALVEFE

HNRNPL

131

P14866
AEVQMKEKFLVTPQD

CENATAC

111

Q86UT8
PIFKVFDAIMNFKKE

EEF2

296

P13639
FIMPIEVHFKNKEEP

MLLT1

81

Q03111
KEVGLDLFFPKQMQE

PTK2B

206

Q14289
EIENKMPKVFDLDQV

DNAH10

4206

Q8IVF4
MPQVKESKRQFIFDV

RYR1

4206

P21817
VVKPIDFETNRMFVL

CDH2

446

P19022
KFFLNKPMLADVVFE

RHOBTB3

411

O94955
FNILVEDKMKLFPVE

PCDHGA1

106

Q9Y5H4
EKKEVPFIFNQVTEM

PLA2G4A

116

P47712
CFEVAMTREKFPEKI

MTOR

2361

P42345
CFITFKEEEPVKKIM

HNRNPD

226

Q14103
PVFITVKMDVLNAFK

PTGFRN

816

Q9P2B2
KDVIMQDFPAEIFLQ

RTTN

211

Q86VV8
EVTDEIVKEFMTPRK

WARS1

451

P23381
MAFREEIAPINFKVK

UTRN

2736

P46939
QNFSKMFEIVFEDPK

EPRS1

1246

P07814
KVNPDMNFEVFIHKV

RRAGC

166

Q9HB90
ELSPREVKEMEQFVK

TES

166

Q9UGI8
IDQMVESKEKDFPII

SLC9C1

926

Q4G0N8
FREMEKSFDEQNVPK

SVIL

701

O95425
PFEEKVEVENVMKRK

SVIL

1036

O95425
LKIQMKDFEVSAEPI

SYNE1

3171

Q8NF91
LVTEFMKVEEPKIAQ

TMEM132B

601

Q14DG7
KPMEQKDFIKFIEFN

SYNE2

4391

Q8WXH0
RDVFNEKPSKEEVMA

PPWD1

466

Q96BP3
QEVQERKMFEFVEPL

ARHGAP26

186

Q9UNA1
LVNEKFREMIPFAVV

SEPTIN9

486

Q9UHD8
DELQDVFLMNFKDPK

SEMA3A

306

Q14563
PVKAIFDKQELEERM

HERC2P3

1106

Q9BVR0
FKLAFVKEPQMQVLE

SERPINB11

221

Q96P15
VSKFIPNEEILMFLE

MROH2B

996

Q7Z745
VMENGKVIEFDKPEV

ABCC12

1326

Q96J65
FEENSKVTVPQMIKR

RASGRF1

596

Q13972
LPEKFIVKGMVERFN

SNX7

96

Q9UNH6
AEKVFEFIDRQPTMV

ABCB9

476

Q9NP78
KVKFKNPLFVLMEEE

CCDC15

301

Q0P6D6
PKVLVVQSFDMFKDK

ARID5B

646

Q14865
KAQLMNDFVAVKIFP

ACVR2B

206

Q13705
ICPFEEKTKVERMVE

ZNF561

16

Q8N587
PDFVDVEKIKVKFMT

RIN2

646

Q8WYP3
PDNFKPEVKMVFELV

VIPR1

361

P32241
PMVEKIFRKSVEFCN

TTC30B

441

Q8N4P2
VNMTTFKIRFEVPKV

VPS13A

876

Q96RL7
VEKFLPFLDMFQKES

VPS35L

566

Q7Z3J2
PFLDMFQKESVRVEV

VPS35L

571

Q7Z3J2
EQKQVEDFAMIPAKE

POLR3C

376

Q9BUI4
VNVKRPMKDETHFEV

VWF

941

P04275
IMVFKDVNTREPKLF

PPP6C

271

O00743
EFLFNAIETMPCVKK

RRM2

191

P31350
APQAMLVEKDKENIF

ZNF775

31

Q96BV0
NVRVIFPFMKIIKDE

ZNF654

331

Q8IZM8
PNGIKMEKFVFDVFR

UAP1L1

376

Q3KQV9
NKTFFIMLKIPEECV

TTMP

106

Q5BVD1
EQADIFERVQKMKPV

TBC1D4

491

O60343
FERVQKMKPVSDQEE

TBC1D4

496

O60343
VKVMPQDLVTFKDVA

ZNF471

6

Q9BX82
PMVEKVFRKSVEFCN

TTC30A

441

Q86WT1
TFKDEELFPLQVVMK

WASHC4

571

Q2M389
FVVQEDFMKAVRKVA

PSMC6

361

P62333
RKIMDEFKVDIRFPQ

HDLBP

1151

Q00341
KDIPQAKEMFIDTVI

TEX15

386

Q9BXT5
MIKFQERVTFKDVAV

ZNF285

1

Q96NJ3
FVLIPFKDMDKQCTV

TMC7

201

Q7Z402
LTPEVNMHIKEEKFF

UGT1A4

61

P22310
IPSQEADKMFFLIEK

MX2

411

P20592
KEDFQMDVFKILAAI

MYO5C

316

Q9NQX4
EKASRMVKFKVPDFE

MYOZ2

196

Q9NPC6