Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GTPase activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D FAM13B TBC1D3C TBC1D3B TBC1D26 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.45e-08	279	126	13	GO:0005096
GeneOntologyMolecularFunction	enzyme activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D FAM13B TBC1D3C TBC1D3B TBC1D26 ABHD5 RPTOR TBC1D3I IL2 TBC1D3G TBC1D3K TBC1D3F	3.83e-06	656	126	16	GO:0008047
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D MYCBP2 FAM13B TBC1D3C TBC1D3B TBC1D26 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	3.96e-06	507	126	14	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D MYCBP2 FAM13B TBC1D3C TBC1D3B TBC1D26 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	3.96e-06	507	126	14	GO:0030695
GeneOntologyMolecularFunction	enzyme regulator activity	TBC1D3E BIN1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D MYCBP2 CIP2A FAM13B TBC1D3C TBC1D3B TBC1D26 ABHD5 SPOCK3 RPTOR WFIKKN2 TBC1D3I IL2 TBC1D3G TBC1D3K TBC1D3F	2.09e-04	1418	126	21	GO:0030234
GeneOntologyMolecularFunction	RNA polymerase III general transcription initiation factor binding	OPTN MTOR	2.35e-04	4	126	2	GO:0001025
GeneOntologyBiologicalProcess	activation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D26 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.73e-12	109	125	12	GO:0090630
GeneOntologyBiologicalProcess	regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D26 PROM2 MTOR TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.64e-08	335	125	14	GO:0043087
GeneOntologyBiologicalProcess	positive regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D26 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	3.10e-08	244	125	12	GO:0043547
GeneOntologyBiologicalProcess	regulation of hydrolase activity	RAG1 TBC1D3E BIN1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D RIPK2 TBC1D3C TBC1D3B TBC1D26 PROM2 CARD9 SPOCK3 MTOR WFIKKN2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	3.21e-07	878	125	20	GO:0051336
GeneOntologyBiologicalProcess	positive regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RIPK2 TBC1D3C TBC1D3B TBC1D26 CARD9 MTOR TBC1D3I TBC1D3G TBC1D3K TBC1D3F	3.65e-07	499	125	15	GO:0051345
Domain	RabGAP-TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D28 TBC1D3C TBC1D3B TBC1D26 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.47e-15	53	129	12	PF00566
Domain	Rab-GTPase-TBC_dom	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D28 TBC1D3C TBC1D3B TBC1D26 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.39e-15	55	129	12	IPR000195
Domain	TBC_RABGAP	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D28 TBC1D3C TBC1D3B TBC1D26 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.39e-15	55	129	12	PS50086
Domain	TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D26 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.58e-14	49	129	11	SM00164
Domain	ARM-like	CIP2A RTTN RANBP6 ZYG11B MEI1 EFR3A MTOR UNC45B RPTOR	1.09e-04	270	129	9	IPR011989
Domain	ARM-type_fold	CIP2A RTTN RANBP6 ZYG11B APOB MEI1 EFR3A MTOR UNC45B RPTOR	1.24e-04	339	129	10	IPR016024
Domain	-	CIP2A RTTN RANBP6 ZYG11B EFR3A MTOR UNC45B RPTOR	1.56e-04	222	129	8	1.25.10.10
Domain	AWS	NSD3 SETD2	4.67e-04	5	129	2	SM00570
Domain	AWS	NSD3 SETD2	4.67e-04	5	129	2	PS51215
Domain	AWS_dom	NSD3 SETD2	4.67e-04	5	129	2	IPR006560
Domain	ZP_dom_CS	TGFBR3 ZP4	2.05e-03	10	129	2	IPR017977
Domain	ZP_2	TGFBR3 ZP4	4.08e-03	14	129	2	PS51034
Domain	ZP_1	TGFBR3 ZP4	4.08e-03	14	129	2	PS00682
Domain	NPIP	NPIPA3 NPIPA2	4.08e-03	14	129	2	IPR009443
Domain	ZP	TGFBR3 ZP4	4.69e-03	15	129	2	SM00241
Domain	Post-SET_dom	NSD3 SETD2	5.33e-03	16	129	2	IPR003616
Domain	PostSET	NSD3 SETD2	5.33e-03	16	129	2	SM00508
Domain	POST_SET	NSD3 SETD2	5.33e-03	16	129	2	PS50868
Domain	ZP_dom	TGFBR3 ZP4	6.02e-03	17	129	2	IPR001507
Domain	Zona_pellucida	TGFBR3 ZP4	6.02e-03	17	129	2	PF00100
Pathway	WP_17Q12_COPY_NUMBER_VARIATION_SYNDROME	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3C TBC1D3B UNC45B TBC1D3I TBC1D3G TBC1D3K	3.30e-10	99	84	10	M46448
Pubmed	TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.54e-27	11	132	11	16863688
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	STAM2 LIMA1 MYCBP2 PPFIA1 CCDC18 RIPK2 PRAG1 NSD3 OPTN MTOR N4BP2 RPTOR PLEKHA3 ANKRD17 TANC1 GEN1 DOP1A VCPIP1	5.01e-09	861	132	18	36931259
Pubmed	DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.	TBC1D3E TBC1D3 TBC1D3H TBC1D3D TBC1D3B TBC1D3G TBC1D3F	1.41e-08	74	132	7	16625196
Pubmed	PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.	TBC1D3 TBC1D3D TBC1D3F	2.13e-07	4	132	3	12359748
Pubmed	Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.	TBC1D3 TBC1D3D TBC1D3F	2.13e-07	4	132	3	8406013
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	STAM2 RNF169 RPGRIP1L MYCBP2 CIP2A PPFIA1 CCDC18 ZYG11B NSD3 CASK EFR3A PHKA1 PTPRE VPS33B KCTD3 TANC1 KNL1	5.16e-07	1049	132	17	27880917
Pubmed	The Tre2 (USP6) oncogene is a hominoid-specific gene.	TBC1D3 TBC1D3D TBC1D3C	5.31e-07	5	132	3	12604796
Pubmed	Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.	TBC1D3 TBC1D3D TBC1D3F	5.31e-07	5	132	3	8471161
Pubmed	IL-2 signaling prevents T cell anergy by inhibiting the expression of anergy-inducing genes.	JAK3 MTOR IL2	5.31e-07	5	132	3	18990450
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	STAM2 RPGRIP1L CIP2A SETD2 N4BP2 CEP44 RPTOR ZNF451 TANC1 FAM135A KNL1 VCPIP1	2.70e-06	588	132	12	38580884
Pubmed	Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.	RAG1 MTOR RPTOR	2.95e-06	8	132	3	29399633
Pubmed	Dnmt3b recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissues.	TEX11 MAEL SYCE1	4.41e-06	9	132	3	20439742
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	RNF169 BIN1 RPGRIP1L MYCBP2 CIP2A PPFIA1 SETD2 ATAD1 N4BP2 ZNF451 TANC1 KNL1 VCPIP1	4.71e-06	733	132	13	34672954
Pubmed	Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.	RIPK2 APBB2 TEX11 ZBTB24 OPTN ABHD5 VPS33B CARD9 CEP44 CBY2 ZFP64 UMPS SYCE1	5.37e-06	742	132	13	26871637
Pubmed	Interleukin-2 critically regulates bone marrow erythropoiesis and prevents anemia development.	RAG1 JAK3 IL2	6.29e-06	10	132	3	26404745
Pubmed	The mTORC1 component RPTOR is required for maintenance of the foundational spermatogonial stem cell pool in mice†.	MTOR RPTOR	1.43e-05	2	132	2	30202948
Pubmed	VPS33B interacts with NESG1 to suppress cell growth and cisplatin chemoresistance in ovarian cancer.	VPS33B CFAP45	1.43e-05	2	132	2	33788346
Pubmed	A role for cell-autocrine interleukin-2 in regulatory T-cell homeostasis.	RAG1 IL2	1.43e-05	2	132	2	32187647
Pubmed	Refining the phenotype associated with CASC5 mutation.	MCPH1 KNL1	1.43e-05	2	132	2	26626498
Pubmed	Hepatic overexpression of a dominant negative form of raptor enhances Akt phosphorylation and restores insulin sensitivity in K/KAy mice.	MTOR RPTOR	1.43e-05	2	132	2	18270303
Pubmed	Initiation of O-glycan synthesis in IgA1 hinge region is determined by a single enzyme, UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2.	GALNT2 GALNT8	1.43e-05	2	132	2	12438318
Pubmed	Deletion of mTORC1 Activity in CD4+ T Cells Is Associated with Lung Fibrosis and Increased γδ T Cells.	MTOR RPTOR	1.43e-05	2	132	2	27649073
Pubmed	mTORC2, but not mTORC1, is required for hippocampal mGluR-LTD and associated behaviors.	MTOR RPTOR	1.43e-05	2	132	2	29786082
Pubmed	Activation of mTORC1 is essential for β-adrenergic stimulation of adipose browning.	MTOR RPTOR	1.43e-05	2	132	2	27018708
Pubmed	Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling.	JAK3 IL2	1.43e-05	2	132	2	27018889
Pubmed	The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity.	MTOR RPTOR	1.43e-05	2	132	2	16847060
Pubmed	mTOR kinase-dependent, but raptor-independent regulation of downstream signaling is important for cell cycle exit and myogenic differentiation.	MTOR RPTOR	1.43e-05	2	132	2	25486193
Pubmed	Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking.	MTOR RPTOR	1.43e-05	2	132	2	17301289
Pubmed	Insulin inhibition of apolipoprotein B mRNA translation is mediated via the PI-3 kinase/mTOR signaling cascade but does not involve internal ribosomal entry site (IRES) initiation.	APOB MTOR	1.43e-05	2	132	2	17698027
Pubmed	Conditional Knockout of Raptor/mTORC1 Results in Dentin Malformation.	MTOR RPTOR	1.43e-05	2	132	2	30984011
Pubmed	Hepatic peroxisomal β-oxidation suppresses lipophagy via RPTOR acetylation and MTOR activation.	MTOR RPTOR	1.43e-05	2	132	2	32687428
Pubmed	IL-2 enhances cervical cancer cells proliferation and JAK3/STAT5 phosphorylation at low doses, while at high doses IL-2 has opposite effects.	JAK3 IL2	1.43e-05	2	132	2	24548303
Pubmed	Inducible colitis-associated glycome capable of stimulating the proliferation of memory CD4+ T cells.	RAG1 IL2	1.43e-05	2	132	2	23209314
Pubmed	Dysregulated myelopoiesis in mice lacking Jak3.	RAG1 JAK3	1.43e-05	2	132	2	10419884
Pubmed	Mitotic raptor promotes mTORC1 activity, G(2)/M cell cycle progression, and internal ribosome entry site-mediated mRNA translation.	MTOR RPTOR	1.43e-05	2	132	2	20439490
Pubmed	The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.	NAPA TBC1D3B THOC5 OPTN KCTD3 GSTO1 SYCE1	2.57e-05	225	132	7	25277244
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF280D MYCBP2 CIP2A PPFIA1 N4BP2 CEP44 ANKRD17 KNL1 VCPIP1	3.31e-05	418	132	9	34709266
Pubmed	Dynamin-2 reduction rescues the skeletal myopathy of a SPEG-deficient mouse model.	BIN1 SPEG	4.28e-05	3	132	2	35763354
Pubmed	Distribution and association of mTOR with its cofactors, raptor and rictor, in cumulus cells and oocytes during meiotic maturation in mice.	MTOR RPTOR	4.28e-05	3	132	2	23440873
Pubmed	mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition.	MTOR RPTOR	4.28e-05	3	132	2	25385646
Pubmed	mTOR has a developmental stage-specific role in mitochondrial fitness independent of conventional mTORC1 and mTORC2 and the kinase activity.	MTOR RPTOR	4.28e-05	3	132	2	28813526
Pubmed	mTOR Signaling in Growth, Metabolism, and Disease.	MTOR RPTOR	4.28e-05	3	132	2	28283069
Pubmed	The effects of IL-2 and Treg cells on dendritic cell homeostasis are mediated indirectly via activation of conventional T cells.	RAG1 IL2	4.28e-05	3	132	2	25590474
Pubmed	Interferon-gamma induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase dependent mammalian target of rapamycin raptor complex 1 activation.	MTOR RPTOR	4.28e-05	3	132	2	17656678
Pubmed	Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy.	MTOR RPTOR	4.28e-05	3	132	2	20008564
Pubmed	Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908.	MTOR RPTOR	4.28e-05	3	132	2	22356909
Pubmed	Targeted next-generation sequencing panel screening of 668 Chinese patients with non-obstructive azoospermia.	TEX11 SYCE1	4.28e-05	3	132	2	33728612
Pubmed	Diversity of human copy number variation and multicopy genes.	TBC1D3E TBC1D3G	4.28e-05	3	132	2	21030649
Pubmed	Janus kinase 3 regulates interleukin 2-induced mucosal wound repair through tyrosine phosphorylation of villin.	JAK3 IL2	4.28e-05	3	132	2	17537734
Pubmed	mTORC1 directly phosphorylates and activates ERα upon estrogen stimulation.	MTOR RPTOR	4.28e-05	3	132	2	26522726
Pubmed	T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming.	RAG1 RPTOR	4.28e-05	3	132	2	24315998
Pubmed	Leucine regulates autophagy via acetylation of the mTORC1 component raptor.	MTOR RPTOR	4.28e-05	3	132	2	32561715
Pubmed	Regulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylation.	MTOR RPTOR	4.28e-05	3	132	2	19864431
Pubmed	Protein kinase C theta plays a fundamental role in different types of chronic colitis.	RAG1 IL2	4.28e-05	3	132	2	18155708
Pubmed	Loss of mTOR complex 1 induces developmental blockage in early T-lymphopoiesis and eradicates T-cell acute lymphoblastic leukemia cells.	MTOR RPTOR	4.28e-05	3	132	2	24567410
Pubmed	mTOR has distinct functions in generating versus sustaining humoral immunity.	MTOR RPTOR	4.28e-05	3	132	2	27760048
Pubmed	Essential role of D1R in the regulation of mTOR complex1 signaling induced by cocaine.	MTOR RPTOR	4.28e-05	3	132	2	26314207
Pubmed	Genetic variations of mTORC1 genes and risk of gastric cancer in an Eastern Chinese population.	MTOR RPTOR	4.28e-05	3	132	2	23423739
Pubmed	Induction of autophagy in Cx3cr1+ mononuclear cells limits IL-23/IL-22 axis-mediated intestinal fibrosis.	RAG1 MTOR	4.28e-05	3	132	2	30765845
Pubmed	Reduced juvenile long-term depression in tuberous sclerosis complex is mitigated in adults by compensatory recruitment of mGluR5 and Erk signaling.	MTOR RPTOR	4.28e-05	3	132	2	23966835
Pubmed	Architecture of human mTOR complex 1.	MTOR RPTOR	4.28e-05	3	132	2	26678875
Pubmed	Single nucleotide polymorphisms of the genes IL-2, IL-2RB, and JAK3 in patients with cutaneous leishmaniasis caused by Leishmania (V.) guyanensis in Manaus, Amazonas, Brazil.	JAK3 IL2	4.28e-05	3	132	2	31393896
Pubmed	mTOR phosphorylated at S2448 binds to raptor and rictor.	MTOR RPTOR	4.28e-05	3	132	2	19145465
Pubmed	Requirement of the mTOR kinase for the regulation of Maf1 phosphorylation and control of RNA polymerase III-dependent transcription in cancer cells.	MTOR RPTOR	4.28e-05	3	132	2	20233713
Pubmed	Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent Inhibition of sirtuin 1.	MTOR RPTOR	4.28e-05	3	132	2	21471201
Pubmed	The Potential Role of BRCA1-Associated ATM Activator-1 (BRAT1) in Regulation of mTOR.	MTOR RPTOR	4.28e-05	3	132	2	25657994
Pubmed	Expression of the mTOR pathway regulators in human pituitary adenomas indicates the clinical course.	MTOR RPTOR	4.28e-05	3	132	2	23898069
Pubmed	Target of rapamycin (TOR)-signaling and RAIP motifs play distinct roles in the mammalian TOR-dependent phosphorylation of initiation factor 4E-binding protein 1.	MTOR RPTOR	4.28e-05	3	132	2	12912989
Pubmed	Localization of Rheb to the endomembrane is critical for its signaling function.	MTOR RPTOR	4.28e-05	3	132	2	16631613
Pubmed	Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function.	MTOR RPTOR	4.28e-05	3	132	2	22143799
Pubmed	Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility.	MTOR RPTOR	4.28e-05	3	132	2	19724909
Pubmed	IL-2 produced by CD8+ immune T cells can augment their IFN-γ production independently from their proliferation in the secondary response to an intracellular pathogen.	RAG1 IL2	4.28e-05	3	132	2	23359502
Pubmed	Conditional Disruption of Raptor Reveals an Essential Role for mTORC1 in B Cell Development, Survival, and Metabolism.	MTOR RPTOR	4.28e-05	3	132	2	27521345
Pubmed	mTORC1 Signaling is a Critical Regulator of Postnatal Tendon Development.	MTOR RPTOR	4.28e-05	3	132	2	29215029
Pubmed	IL-2-controlled expression of multiple T cell trafficking genes and Th2 cytokines in the regulatory T cell-deficient scurfy mice: implication to multiorgan inflammation and control of skin and lung inflammation.	RAG1 IL2	4.28e-05	3	132	2	21169543
Pubmed	Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1.	MTOR RPTOR	4.28e-05	3	132	2	18614546
Pubmed	mTORC1 pathway disruption ameliorates brain inflammation following stroke via a shift in microglia phenotype from M1 type to M2 type.	MTOR RPTOR	4.28e-05	3	132	2	27342766
Pubmed	Parkin ubiquitinates mTOR to regulate mTORC1 activity under mitochondrial stress.	MTOR RPTOR	4.28e-05	3	132	2	25007995
Pubmed	Cutting edge: mTORC1 in intestinal CD11c+ CD11b+ dendritic cells regulates intestinal homeostasis by promoting IL-10 production.	MTOR RPTOR	4.28e-05	3	132	2	22504639
Pubmed	The human myometrium differentially expresses mTOR signalling components before and during pregnancy: evidence for regulation by progesterone.	MTOR RPTOR	4.28e-05	3	132	2	23541542
Pubmed	Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.	MTOR RPTOR	4.28e-05	3	132	2	12408816
Pubmed	GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling.	MTOR RPTOR	4.28e-05	3	132	2	26348909
Pubmed	Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9.	CARD9 IL2	4.28e-05	3	132	2	21425313
Pubmed	Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells.	MTOR RPTOR	4.28e-05	3	132	2	25849663
Pubmed	The Rapamycin-Sensitive Complex of Mammalian Target of Rapamycin Is Essential to Maintain Male Fertility.	MTOR RPTOR	4.28e-05	3	132	2	26683665
Pubmed	A dynamic dual role of IL-2 signaling in the two-step differentiation process of adaptive regulatory T cells.	RAG1 IL2	4.28e-05	3	132	2	23427250
Pubmed	Reconstitution of leucine-mediated autophagy via the mTORC1-Barkor pathway in vitro.	MTOR RPTOR	4.28e-05	3	132	2	22258093
Pubmed	TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function.	MTOR RPTOR	4.28e-05	3	132	2	12747827
Pubmed	Identification of Pathogenic Mutations in Primary Microcephaly- (MCPH-) Related Three Genes CENPJ, CASK, and MCPH1 in Consanguineous Pakistani Families.	MCPH1 CASK	4.28e-05	3	132	2	35281599
Pubmed	Langerhans cell homeostasis in mice is dependent on mTORC1 but not mTORC2 function.	MTOR RPTOR	4.28e-05	3	132	2	23212520
Pubmed	mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress.	MTOR RPTOR	4.28e-05	3	132	2	24958889
Pubmed	Hexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibition.	MTOR RPTOR	4.28e-05	3	132	2	24462113
Pubmed	Reprogramming tumor-associated macrophages to outcompete endovascular endothelial progenitor cells and suppress tumor neoangiogenesis.	RAG1 RPTOR	4.28e-05	3	132	2	37967531
Pubmed	Stress and mTORture signaling.	MTOR RPTOR	4.28e-05	3	132	2	17041623
Pubmed	mLST8 Promotes mTOR-Mediated Tumor Progression.	MTOR RPTOR	4.28e-05	3	132	2	25906254
Pubmed	Loss of Optineurin Drives Cancer Immune Evasion via Palmitoylation-Dependent IFNGR1 Lysosomal Sorting and Degradation.	RAG1 OPTN	4.28e-05	3	132	2	33627378
Pubmed	mTOR/Raptor signaling is critical for skeletogenesis in mice through the regulation of Runx2 expression.	MTOR RPTOR	4.28e-05	3	132	2	28686577
Pubmed	VHL suppresses RAPTOR and inhibits mTORC1 signaling in clear cell renal cell carcinoma.	MTOR RPTOR	4.28e-05	3	132	2	34290272
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ZYG11B SETD2 CEP44 ZNF451 TANC1	4.53e-05	102	132	5	11214970
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	RPGRIP1L PPFIA1 CCDC18 CEP128 PHKA1 VPS33B CEP44	5.14e-05	251	132	7	29778605
Interaction	YWHAH interactions	OARD1 STAM2 LIMA1 RPGRIP1L MYCBP2 SPEG PPFIA1 CCDC18 RIPK2 CEP128 PRAG1 NSD3 OPTN MTOR RPTOR PLEKHA3 ANKRD17 TANC1 GEN1 DOP1A VCPIP1	6.70e-06	1102	129	21	int:YWHAH
Interaction	TRIM41 interactions	ZNF138 RPGRIP1L CEP128 ZBTB24 TBC1D26 CEP44 ZFP64 ANKRD17 SYCE1	1.37e-05	223	129	9	int:TRIM41
Cytoband	Ensembl 112 genes in cytogenetic band chr17q12	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B UNC45B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.18e-14	149	132	12	chr17q12
Cytoband	17q12	TBC1D3 TBC1D3H TBC1D3C TBC1D3B UNC45B TBC1D3F	4.53e-07	99	132	6	17q12
GeneFamily	MTOR complex 1\|MTOR complex 2	MTOR RPTOR	8.32e-05	4	68	2	1332
Coexpression	PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP	MCPH1 CCDC18 NSD3 CASK CEP44 KCTD3 GEN1 KNL1	5.12e-06	195	127	8	M13736
Coexpression	GSE20727_CTRL_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_UP	OARD1 MYCBP2 CDRT4 PTPRE RPTOR ZFP64 KCTD3 PID1	5.52e-06	197	127	8	M9250
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	4.25e-09	90	130	9	PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D PRAG1 TBC1D3C TBC1D3B CDRT4 TBC1D3G TBC1D3K TBC1D3F	4.53e-06	320	130	11	PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	6.70e-06	213	130	9	PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	6.70e-06	213	130	9	PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	CIP2A CCDC18 DGKD TEX11 PHKA1 TRMT10A VPS33B BRDT MTOR ZNF451 KCTD3 MAEL CPLANE1 DNAH8 FAM135A SYCE1 DOP1A	1.09e-05	820	130	17	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlas	DE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	1.86e-05	242	130	9	PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_1000	MYCBP2 TRIM35 SPEG ZYG11B NSD3 CASK EFR3A TRPM5 CPLANE1 FAM135A	2.29e-05	312	130	10	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k2
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#2_top-relative-expression-ranked_500	CCDC18 TEX11 BRDT MAEL SYCE1	2.37e-05	56	130	5	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k2_500
CoexpressionAtlas	DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#1_top-relative-expression-ranked_200	DGKD JAK3 BRDT MAEL	2.83e-05	29	130	4	gudmap_developingGonad_e14.5_ testes_200_k1
CoexpressionAtlas	DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#5_top-relative-expression-ranked_1000	MYCBP2 TRIM35 DGKD ZYG11B CASK CPLANE1 FAM135A KNL1	3.40e-05	201	130	8	gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000_k5
CoexpressionAtlas	Mesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	5.97e-05	281	130	9	PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	5.97e-05	281	130	9	PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#2_top-relative-expression-ranked_500	TEX11 BRDT MAEL DNAH8 SYCE1	6.09e-05	68	130	5	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k2_500
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	TEX11 BRDT MAEL CPLANE1 DNAH8 SYCE1	7.65e-05	115	130	6	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k2_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_200	TEX11 BRDT MAEL	7.77e-05	14	130	3	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k4_200
CoexpressionAtlas	DevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#1_top-relative-expression-ranked_100	JAK3 BRDT MAEL	2.37e-04	20	130	3	gudmap_developingGonad_e16.5_testes_100_k1
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_200	CCDC18 TEX11 BRDT MAEL DNAH8 SYCE1	2.52e-04	143	130	6	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_200
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	CIP2A CCDC18 TRMT10A VPS33B MTOR ZNF451 KCTD3 CPLANE1 FAM135A	3.89e-04	361	130	9	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_1000
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000	GTPBP4 CIP2A CCDC18 DHX33 TEX11 TRMT10A OPTN BRDT MTOR ZNF451 MAEL CPLANE1 FAM135A SYCE1	4.50e-04	810	130	14	gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlas	dev gonad_e11.5_F_PrimGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	CIP2A CCDC18 MAEL DNAH8 SYCE1	4.51e-04	104	130	5	gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_k2_1000
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#1_top-relative-expression-ranked_200	TEX11 MAEL SYCE1	4.67e-04	25	130	3	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k1_200
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_D\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	NUGGC PPFIA1 APBB2 RANBP6 CEP128 DOP1A	5.33e-06	148	132	6	10dcbdb47cac908648d9d652c8095b536db19b8a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KCNH7 CIP2A CCDC18 CEP128 GEN1 KNL1	1.39e-05	175	132	6	876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_C\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RPGRIP1L SPEG DHX33 CARD9 PID1 SYCE1	1.53e-05	178	132	6	50bb1f2c6a8d050ff2af217fd76c3b1b7b4a4a69
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF729 CIP2A CCDC18 CEP128 GEN1 KNL1	1.73e-05	182	132	6	336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNRK GTF2H2 ABHD5 UNC45B DNAH8 FAM135A	1.96e-05	186	132	6	39e475a3c167b33daa63b0c1bfa32451c5f46635
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SNRK GTF2H2 ABHD5 UNC45B DNAH8 FAM135A	1.96e-05	186	132	6	02418c50fdcca549bf73dedf6199ab4a27862a9b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF729 CIP2A CCDC18 CEP128 GEN1 KNL1	2.02e-05	187	132	6	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NUGGC CIP2A MEI1 CEP128 GEN1 KNL1	2.08e-05	188	132	6	567b08514d9d84cbb40f9b7a679eec304f023428
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CIP2A RTTN CCDC18 CEP128 GEN1 KNL1	2.41e-05	193	132	6	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
Disease	macrophage inflammatory protein 1b measurement	TBC1D3 SNRK TBC1D3B SETD2 ABHD5 UNC45B TBC1D3F	1.46e-06	136	120	7	EFO_0008219
Disease	Primary microcephaly	MCPH1 RTTN TRMT10A KNL1	1.80e-06	22	120	4	C0431350
Disease	CCL4 measurement	TBC1D3 SETD2 TBC1D3F	7.11e-05	20	120	3	EFO_0004751
Disease	Myopathy, Centronuclear, Autosomal Recessive	BIN1 SPEG	9.79e-05	4	120	2	C0410204
Disease	Malignant neoplasm of breast	AKAP6 THOC5 MRPS7 SETD2 TRMT10A MTOR UNC45B N4BP2 ZFP64 UMPS CLUL1 KAT6B GEN1 DOP1A	1.22e-04	1074	120	14	C0006142
Disease	tongue squamous cell carcinoma (biomarker_via_orthology)	JAK3 IL2	2.43e-04	6	120	2	DOID:0050865 (biomarker_via_orthology)
Disease	Ovarian Mucinous Adenocarcinoma	SPEG SNRK MTOR	2.71e-04	31	120	3	C1335167
Disease	Cerebellar Diseases	RPGRIP1L CASK	3.40e-04	7	120	2	C0007760
Disease	thiamine measurement	ANO5 N4BP2	7.23e-04	10	120	2	EFO_0010540
Disease	Gastric Adenocarcinoma	SPEG JAK3 BRDT	8.22e-04	45	120	3	C0278701
Disease	diet measurement, adiponectin measurement	SPOCK3 PDE11A	8.81e-04	11	120	2	EFO_0004502, EFO_0008111
Disease	kidney cancer	MCPH1 CARD9	8.81e-04	11	120	2	MONDO_0002367
Disease	triglycerides to total lipids in medium LDL percentage	GALNT2 APOB NPIPA2	1.12e-03	50	120	3	EFO_0022334
Disease	seasonal gut microbiome measurement	MCPH1 CEP128 TRMT10A PID1	1.15e-03	112	120	4	EFO_0007753
Disease	refractive error, age at onset, Myopia	AKAP6 FRMPD2 MEI1 TBC1D3B PDE11A	1.18e-03	193	120	5	EFO_0004847, HP_0000545, MONDO_0004892
Disease	triglycerides to total lipids in large LDL percentage	GALNT2 APOB NPIPA2	1.18e-03	51	120	3	EFO_0022331
Disease	severe combined immunodeficiency (is_implicated_in)	RAG1 JAK3	1.45e-03	14	120	2	DOID:627 (is_implicated_in)
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	APOB ANKRD17	1.45e-03	14	120	2	EFO_0004611, EFO_0008589
Disease	leukemia	SETD2 IL2 GSTO1	1.48e-03	55	120	3	C0023418
Disease	triacylglycerol 52:3 measurement	GALNT2 APOB	1.66e-03	15	120	2	EFO_0010415
Disease	Autosomal recessive primary microcephaly	MCPH1 KNL1	1.66e-03	15	120	2	cv:C3711387
Disease	Autosomal Recessive Centronuclear Myopathy	BIN1 SPEG	1.66e-03	15	120	2	C3645536
Disease	creatine kinase measurement	AKAP6 BIN1 ANO5	1.81e-03	59	120	3	EFO_0004534
Disease	Malignant Neoplasms	SETD2 MTOR IL2 GSTO1	1.88e-03	128	120	4	C0006826
Disease	primary autosomal recessive microcephaly (is_implicated_in)	MCPH1 KNL1	1.90e-03	16	120	2	DOID:0070296 (is_implicated_in)
Disease	Hypercholesterolemia, Familial	APOB ABCG5	2.40e-03	18	120	2	C0020445
Disease	common carotid intimal medial thickness	MCPH1 APOB PRAG1	2.60e-03	67	120	3	EFO_0004860
Disease	Omenn Syndrome	RAG1 JAK3	2.68e-03	19	120	2	C2700553
Disease	Familial aplasia of the vermis	RPGRIP1L CPLANE1	2.97e-03	20	120	2	cv:C0431399
Disease	Severe Combined Immunodeficiency	RAG1 JAK3	2.97e-03	20	120	2	C0085110
Disease	end stage renal disease (implicated_via_orthology)	GTPBP4 MTOR	2.97e-03	20	120	2	DOID:783 (implicated_via_orthology)
Disease	docosahexaenoic acid to total fatty acids percentage	GALNT2 APOB	3.27e-03	21	120	2	EFO_0022262
Disease	age at onset, Myopia	AKAP6 FRMPD2 TBC1D3B PDE11A	3.34e-03	150	120	4	EFO_0004847, HP_0000545
Disease	Autosomal Recessive Primary Microcephaly	MCPH1 KNL1	3.59e-03	22	120	2	C3711387

Protein segments in the cluster

Peptide	Gene	Start	Entry
RLQFLTCKEKMDHKT	ZNF280D	481	Q6N043
RCMERKDKEKAHLAS	CEP128	386	Q6ZU80
LHEICSKIMAERKNA	APBB2	541	Q92870
EAMCKHRKLNAVTKE	ANO5	431	Q75V66
CSEILKEMLAKKHFS	BRDT	276	Q58F21
LLRLMFKSKCKSLES	ADGB	961	Q8N7X0
CDRLLAHRVETKMKG	GTPBP4	336	Q9BZE4
DILNCVMKKHKELSS	CEP44	111	Q9C0F1
LSKRLKHKDDSVMKA	C22orf31	101	O95567
SDMLSKCKVQKVILH	DOP1A	1516	Q5JWR5
DVKTKITREEKHFMC	ANGPTL5	66	Q86XS5
YIATITDKEMLKKCH	ANKRD17	1421	O75179
SLMKAEDDCKVERKH	CARD9	216	Q9H257
FRDKCMLPKSLEKHE	EFR3A	641	Q14156
PKTHRKMARKECDLN	ATXN7L2	226	Q5T6C5
LDLVKKVLASHKCQM	GMEB2	291	Q9UKD1
DVMKKIANCSKIHLS	RAG1	261	P15918
TEVLLKVMDAKHKNC	JAK3	551	P52333
MAFKLKSKSCHDLSV	GEM	281	P55040
EKLILSHMEKLKTCS	KAT6B	961	Q8WYB5
KRLIEKSKTRELECM	CDRT4	41	Q8N9R6
LQKSLEAMKSHCLKN	OARD1	96	Q9Y530
TEDLKREASICHMLK	CASK	56	O14936
VMLTNLKERKEEKCH	PTPRE	231	P23469
RLCMMSSHLKKTEKA	MFAP3L	171	O75121
CLKHMAKASEIRQDL	MAEL	226	Q96JY0
MNEHLSSLIKKKRKC	MCPH1	96	Q8NEM0
LKDHSTESKKMENCL	LIMA1	151	Q9UHB6
RLKCCSLEKQLHSMK	RPGRIP1L	321	Q68CZ1
AMKLNECVDHTPKLK	GSTO1	186	P78417
KGCLRALAMKFKTTH	KCNH7	751	Q9NS40
TCDLMSLVTKAKELH	PHKA1	696	P46020
ESLKEELMCLKKNHE	KRT32	221	Q14532
RCLPEDIKKMTKDHL	FAM13B	691	Q9NYF5
KEKSVKHMDLCLTVV	GALNT2	486	Q10471
LKDMSKIILNAKCHA	CFAP45	191	Q9UL16
HSARIEMCKTALKDK	FAM135A	1431	Q9P2D6
ECESKLEAKKLAHAM	PID1	201	Q7Z2X4
IVKKIMHRAQTLLKC	PDE11A	406	Q9HCR9
ALAKKLKLECRTISM	DNAH8	3926	Q96JB1
CLKELMELKTKAREL	L1RE1	86	Q9UN81
ECLVDARMLDHLTKK	PPFIA1	986	Q13136
KMRHCSDKELKAFGI	KNL1	1981	Q8NG31
ICKMKVTTKVNRHDK	NPIPA3	121	F8WFD2
CKMKVTTKVNRHDKI	NPIPA2	141	E9PIF3
DASEEKKARHMRKCA	IP6K3	226	Q96PC2
VAMKLLHQVSKLCGK	MEI1	931	Q5TIA1
AAHCMDESKKLLVRL	PROC	251	P04070
KLHHKRLAKECMLQE	CBY2	156	Q8NA61
LMGHLSCDTKEERKI	APOB	1106	P04114
MPKKATELKHLQCLE	IL2	66	P60568
ELTSIHKPTDKRKMC	CPLANE1	1501	Q9H799
EKLRKMEEKCESAAH	CCDC18	836	Q5T9S5
MEKESCSHLKSDLVR	FRMPD2	1096	Q68DX3
DVSSRMALREKLKCK	GALNT8	461	Q9NY28
TKRCLEMKKDLLGSH	GALNT8	596	Q9NY28
IEAMSKTCRDIAKHL	DHX33	301	Q9H6R0
KSAICHKTLKNIERM	ABCG5	331	Q9H222
LLHSCTTEKDSRKMK	LTO1	66	Q8WV07
KAMVHTSCKESLLTK	DGKD	271	Q16760
TRKILMKKSVCLDRH	GEN1	786	Q17RS7
CLTMKEKKSSISQIH	CCDC168	2296	Q8NDH2
SVKAMHEASKKLNEC	BIN1	71	O00499
KIMLSEKHLVSVCAD	KCTD3	426	Q9Y597
AHTKLSEAELMKKRL	OPTN	316	Q96CV9
TMNHVLSCVKKEKER	MTOR	416	P42345
DIKMHAVVKKLCLID	RTTN	861	Q86VV8
CLDLLTEMSKYKHKS	RTTN	2101	Q86VV8
CRDKKHQRTLMPEKL	MRPS7	191	Q9Y2R9
CRDVALVVTKMDKLH	NUGGC	346	Q68CJ6
AKCRNMEHALREKAK	TRIM35	146	Q9UPQ4
EKHKLAKLCGMLTIT	OVCH1	486	Q7RTY7
AAAGHMKLVCLLTKK	TANC1	976	Q9C0D5
RKILSEGVDHCMVKL	MYCBP2	1506	O75592
SDSRECKLMKKLLEA	NAPA	236	P54920
DAKLDKTCISRAMKI	RNF169	556	Q8NCN4
MKEKGKRSSRIIHCI	TBC1D26	131	Q86UD7
ALAAAQRCHKKVMKE	ESRP2	531	Q9H6T0
EDTVLKHLRASMKKL	TBC1D3L	336	B9A6J9
KLETHASMRKKLCDI	RANBP6	106	O60518
SHVSKECKDLITRML	SNRK	236	Q9NRH2
MKKRHCEKIEGSKSL	RPTOR	31	Q8N122
SISHLKEAEEKMLKC	ABHD5	31	Q8WTS1
MSIRHLKKTELLSKV	AKAP6	1006	Q13023
LHRAIEKMKKSKDAA	ATAD1	336	Q8NBU5
TLKMHIAKILTTVKC	CIP2A	431	Q8TCG1
KEKEHTNLMSTLKKC	CLUL1	66	Q15846
EDTVLKHLRASMKKL	TBC1D3B	336	A6NDS4
EDTVLKHLRASMKKL	TBC1D3H	336	P0C7X1
LTAAHKKLCLKMTQV	UNC45B	831	Q8IWX7
CKKELTRKDTIMAHV	ZNF451	536	Q9Y4E5
ACKDRLKSLTMHHLK	ZYG11B	206	Q9C0D3
LSLMREKLCESKESH	ZNF20	66	P17024
DKSLCMLSRLTQHKK	ZNF138	116	P52744
ACKILKEMSHLETEA	TRPM5	551	Q9NZQ8
KMHFDGRKCKLLLTS	SPEG	1016	Q15772
EDTVLKHLRASMKKL	TBC1D3F	336	A6NER0
KTEHKALACERAALM	PROM2	141	Q8N271
FSHKIHLETMCEVKK	PYROXD1	251	Q8WU10
KHITSLKKAVDMTCH	GTF2H2	126	Q13888
KHTMLQECKERISAL	SYCE1	126	Q8N0S2
HRETKKMFCEVDKSL	TRIM51	96	Q9BSJ1
SVSSAIHLCDKKKME	RIPK2	316	O43353
IHLCDKKKMELSLNI	RIPK2	321	O43353
HFAKEESALMCKKLT	SOGA1	151	O94964
TLDVMKELITLAKCH	UMPS	291	P11172
SEDKKKEMDRLLTCL	TEX11	596	Q8IYF3
AHPKVCEKLKSLMVE	STAM2	101	O75886
EDTVLKHLRASMKKL	TBC1D3E	336	A0A087X179
AAKKAVMDNRLHKCL	VCPIP1	456	Q96JH7
RHLLKMNKSSSDLEK	PRAG1	721	Q86YV5
MCETKILSLKKRHFS	ZNF829	111	Q3KNS6
ACSMEKDIHKASKGR	NSD3	801	Q9BZ95
RCKEKDLDDTCMLHK	SETD2	726	Q9BYW2
LKMKCSRHKVCIAQD	SPOCK3	91	Q9BQ16
KGSIKMAVCEIKVHS	PLEKHA3	41	Q9HB20
CHRKFMDVSQLKKHL	ZBTB24	411	O43167
MKEKGKRSSRIIHCI	TBC1D28	131	Q2M2D7
DCSFDHLMVLKDIKK	TRMT10A	106	Q8TBZ6
EDTVLKHLRASMKKL	TBC1D3D	336	A0A087WVF3
KIKNVHMRGLDKETC	UBE4A	476	Q14139
LKRHPLSVMLDLKCK	THOC5	341	Q13769
EDTVLKHLRASMKKL	TBC1D3G	336	Q6DHY5
EDTVLKHLRASMKKL	TBC1D3	336	Q8IZP1
GKCFSRKDKLKTHMR	ZFP64	181	Q9NTW7
EDTVLKHLRASMKKL	TBC1D3K	336	A0A087X1G2
LSLHIGACESIMKKK	VPS33B	341	Q9H267
EHKVVTERKLLKCPM	ZP4	116	Q12836
EDTVLKHLRASMKKL	TBC1D3I	336	A0A087WXS9
EDTVLKHLRASMKKL	TBC1D3C	336	Q6IPX1
ELTLCTKMEKHPQKL	TGFBR3	706	Q03167
SMCFHDRLKTLTKIK	ZNF560	696	Q96MR9
RLRKDCKSANEGKMH	ZNF729	121	A6NN14
RKCFDLKILKSLSME	ZW10	151	O43264
KLREVMHKKTCDVLK	WFIKKN2	556	Q8TEU8
MHKKTCDVLKEFLGL	WFIKKN2	561	Q8TEU8
EIHKLKDMTCLKPSI	MXRA5	266	Q9NR99
KHNLKRETLMFEKDC	N4BP2	1506	Q86UW6