Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transporter activity	SLC52A1 SLC11A2 IPO8 RHBG GC ATP8B1 ATG2A NDUFA10 AQP1 SLC30A4 AQP4 KCNK7 SLC2A1 RHCE ABCG1 CLCA1 SLC15A1 SLC15A2 PKD1 SLC35F6 LRP2 NIPAL2 ANO7 SLC16A8	3.31e-05	1289	150	24	GO:0005215
GeneOntologyMolecularFunction	ammonium channel activity	RHBG AQP1 RHCE	8.70e-05	12	150	3	GO:0008519
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC52A1 SLC11A2 IPO8 RHBG GC NDUFA10 AQP1 SLC30A4 AQP4 KCNK7 SLC2A1 RHCE ABCG1 CLCA1 SLC15A1 SLC15A2 PKD1 SLC35F6 NIPAL2 ANO7 SLC16A8	2.03e-04	1180	150	21	GO:0022857
GeneOntologyMolecularFunction	ATP-dependent activity	DHX16 IPO8 VWA8 MYO10 MYO1H BTAF1 ATP8B1 ABCG1 MDN1 FBH1 SHPRH ACSBG2 DNAH9 KIF25	2.24e-04	614	150	14	GO:0140657
GeneOntologyMolecularFunction	carbon dioxide transmembrane transporter activity	RHBG AQP1	3.33e-04	4	150	2	GO:0035379
GeneOntologyMolecularFunction	peptide:proton symporter activity	SLC15A1 SLC15A2	3.33e-04	4	150	2	GO:0015333
GeneOntologyMolecularFunction	dipeptide transmembrane transporter activity	SLC15A1 SLC15A2	5.52e-04	5	150	2	GO:0071916
GeneOntologyCellularComponent	apical part of cell	SLC11A2 FRMPD2 ATP8B1 AQP1 SLC2A1 FZD6 SPTBN5 HAVCR1 AJAP1 SLC15A1 SLC15A2 LRP2 SCRIB SLC16A8 PDZD2	2.63e-05	592	151	15	GO:0045177
GeneOntologyCellularComponent	cluster of actin-based cell projections	SLC11A2 ATP8B1 AQP1 HAVCR1 SLC15A1 CEACAM16 LRP2 STRC STRCP1	3.62e-05	223	151	9	GO:0098862
GeneOntologyCellularComponent	basal part of cell	SLC11A2 RHBG FRMPD2 AQP1 AQP4 CLDN8 SLC2A1 AJAP1 PKD1 SCRIB SLC16A8	9.81e-05	378	151	11	GO:0045178
GeneOntologyCellularComponent	basolateral plasma membrane	RHBG FRMPD2 AQP1 AQP4 CLDN8 SLC2A1 AJAP1 PKD1 SCRIB SLC16A8	1.15e-04	320	151	10	GO:0016323
GeneOntologyCellularComponent	apical plasma membrane	SLC11A2 ATP8B1 AQP1 SLC2A1 FZD6 HAVCR1 AJAP1 SLC15A1 SLC15A2 LRP2 SCRIB SLC16A8	2.24e-04	487	151	12	GO:0016324
GeneOntologyCellularComponent	basal plasma membrane	RHBG FRMPD2 AQP1 AQP4 CLDN8 SLC2A1 AJAP1 PKD1 SCRIB SLC16A8	2.59e-04	354	151	10	GO:0009925
GeneOntologyCellularComponent	stereocilium tip	CEACAM16 STRC STRCP1	5.14e-04	22	151	3	GO:0032426
GeneOntologyCellularComponent	brush border	SLC11A2 ATP8B1 AQP1 HAVCR1 SLC15A1 LRP2	8.39e-04	152	151	6	GO:0005903
GeneOntologyCellularComponent	apicolateral plasma membrane	ZG16B CLDN8 FZD6	1.06e-03	28	151	3	GO:0016327
GeneOntologyCellularComponent	cell projection membrane	TMEM67 SLC11A2 MYO10 ATP8B1 AQP1 AQP4 MAPK8IP3 PKD1 LRP2 ROM1	1.19e-03	431	151	10	GO:0031253
MousePheno	abnormal membranous labyrinth morphology	ATP8B1 SLC30A4 EDNRB MCTP1 TMPRSS3 CEACAM16 LRP2 SCRIB STRC SLITRK6 STRCP1	6.73e-06	262	110	11	MP:0000035
MousePheno	abnormal cochlear labyrinth morphology	ATP8B1 EDNRB MCTP1 TMPRSS3 CEACAM16 LRP2 SCRIB STRC SLITRK6 STRCP1	1.61e-05	235	110	10	MP:0004426
MousePheno	abnormal scala media morphology	ATP8B1 EDNRB MCTP1 TMPRSS3 CEACAM16 LRP2 SCRIB STRC SLITRK6 STRCP1	1.61e-05	235	110	10	MP:0003169
MousePheno	abnormal cochlea morphology	ATP8B1 EDNRB MCTP1 TMPRSS3 CEACAM16 LRP2 SCRIB STRC SLITRK6 STRCP1	2.55e-05	248	110	10	MP:0000031
MousePheno	abnormal inner ear morphology	ATP8B1 SLC30A4 EDNRB MCTP1 TMPRSS3 CEACAM16 LRP2 SCRIB STRC SLITRK6 STRCP1	2.62e-05	303	110	11	MP:0000026
Domain	ARM-type_fold	CAND1 IPO8 NBEAL1 DOCK9 FHOD3 BTAF1 MEI1 WDFY4 AP4E1 TELO2 AP1G2 UTP20 GCN1 TBCD	4.12e-07	339	145	14	IPR016024
Domain	ARM-like	CAND1 IPO8 FHOD3 BTAF1 MEI1 WDFY4 AP4E1 TELO2 AP1G2 UTP20 GCN1 TBCD	1.34e-06	270	145	12	IPR011989
Domain	-	CAND1 IPO8 BTAF1 WDFY4 AP4E1 TELO2 AP1G2 UTP20 GCN1 TBCD	9.37e-06	222	145	10	1.25.10.10
Domain	Pkinase_C	CDC42BPG RPS6KA4 PRKCQ DMPK MAST3	1.78e-05	42	145	5	PF00433
Domain	HEAT	CAND1 BTAF1 UTP20 GCN1 TBCD	3.44e-05	48	145	5	PF02985
Domain	Oligopep_transport	SLC15A1 SLC15A2	5.99e-05	2	145	2	IPR004768
Domain	AGC-kinase_C	CDC42BPG RPS6KA4 PRKCQ DMPK MAST3	7.31e-05	56	145	5	IPR000961
Domain	AGC_KINASE_CTER	CDC42BPG RPS6KA4 PRKCQ DMPK MAST3	7.31e-05	56	145	5	PS51285
Domain	S_TK_X	CDC42BPG RPS6KA4 PRKCQ DMPK MAST3	7.31e-05	56	145	5	SM00133
Domain	HEAT	CAND1 BTAF1 UTP20 GCN1 TBCD	8.66e-05	58	145	5	IPR000357
Domain	ATPase_dyneun-rel_AAA	VWA8 MDN1 DNAH9	1.57e-04	14	145	3	IPR011704
Domain	AAA_5	VWA8 MDN1 DNAH9	1.57e-04	14	145	3	PF07728
Domain	PTR2_symporter_CS	SLC15A1 SLC15A2	1.79e-04	3	145	2	IPR018456
Domain	PTR2_1	SLC15A1 SLC15A2	1.79e-04	3	145	2	PS01022
Domain	HEAT_REPEAT	CAND1 BTAF1 UTP20 GCN1 TBCD	2.12e-04	70	145	5	PS50077
Domain	DUF2476	PRR23B PRR23C	3.56e-04	4	145	2	PF10630
Domain	Myotonic_dystrophy_kinase_coil	CDC42BPG DMPK	3.56e-04	4	145	2	IPR014930
Domain	PRR23	PRR23B PRR23C	3.56e-04	4	145	2	IPR018903
Domain	Myotonic_dystrophy_kinase_coil	CDC42BPG DMPK	3.56e-04	4	145	2	PD011252
Domain	PTR2_2	SLC15A1 SLC15A2	3.56e-04	4	145	2	PS01023
Domain	DMPK_coil	CDC42BPG DMPK	3.56e-04	4	145	2	PF08826
Domain	POT_fam	SLC15A1 SLC15A2	5.89e-04	5	145	2	IPR000109
Domain	PTR2	SLC15A1 SLC15A2	5.89e-04	5	145	2	PF00854
Domain	Ammonium_transpt	RHBG RHCE	5.89e-04	5	145	2	IPR001905
Domain	Ammonium_transp	RHBG RHCE	5.89e-04	5	145	2	PF00909
Domain	NH4_transpt_AmtB-like_dom	RHBG RHCE	5.89e-04	5	145	2	IPR024041
Domain	RhesusRHD	RHBG RHCE	5.89e-04	5	145	2	IPR002229
Domain	-	RHBG RHCE	1.23e-03	7	145	2	1.10.3430.10
Domain	Ammonium/urea_transptr	RHBG RHCE	1.23e-03	7	145	2	IPR029020
Domain	PH-BEACH_dom	NBEAL1 WDFY4	1.63e-03	8	145	2	IPR023362
Domain	-	NBEAL1 WDFY4	1.63e-03	8	145	2	2.30.29.40
Domain	PH_BEACH	NBEAL1 WDFY4	1.63e-03	8	145	2	PS51783
Domain	Tetraspanin	TSPAN31 TSPAN13 ROM1	1.93e-03	32	145	3	IPR000301
Domain	BEACH	NBEAL1 WDFY4	2.08e-03	9	145	2	PS50197
Domain	Beach	NBEAL1 WDFY4	2.08e-03	9	145	2	PF02138
Domain	-	NBEAL1 WDFY4	2.08e-03	9	145	2	1.10.1540.10
Domain	Beach	NBEAL1 WDFY4	2.08e-03	9	145	2	SM01026
Domain	BEACH_dom	NBEAL1 WDFY4	2.08e-03	9	145	2	IPR000409
Domain	Tetraspanin/Peripherin	TSPAN31 TSPAN13 ROM1	2.11e-03	33	145	3	IPR018499
Domain	Tetraspannin	TSPAN31 TSPAN13 ROM1	2.11e-03	33	145	3	PF00335
Domain	MIP_CS	AQP1 AQP4	2.59e-03	10	145	2	IPR022357
Domain	Pkinase_C	CDC42BPG RPS6KA4 PRKCQ	2.94e-03	37	145	3	IPR017892
Domain	Link_dom	STAB2 HAPLN2	4.41e-03	13	145	2	IPR000538
Domain	Xlink	STAB2 HAPLN2	4.41e-03	13	145	2	PF00193
Domain	LINK_2	STAB2 HAPLN2	4.41e-03	13	145	2	PS50963
Domain	LINK	STAB2 HAPLN2	4.41e-03	13	145	2	SM00445
Domain	LINK_1	STAB2 HAPLN2	4.41e-03	13	145	2	PS01241
Domain	MIP	AQP1 AQP4	5.12e-03	14	145	2	PF00230
Domain	MS4A	MS4A15 MS4A8	5.12e-03	14	145	2	IPR030417
Domain	MIP	AQP1 AQP4	5.12e-03	14	145	2	PS00221
Domain	Clathrin/coatomer_adapt-like_N	AP4E1 AP1G2	5.88e-03	15	145	2	IPR002553
Domain	-	AQP1 AQP4	5.88e-03	15	145	2	1.20.1080.10
Domain	Aquaporin-like	AQP1 AQP4	5.88e-03	15	145	2	IPR023271
Domain	Adaptin_N	AP4E1 AP1G2	5.88e-03	15	145	2	PF01602
Domain	MIP	AQP1 AQP4	5.88e-03	15	145	2	IPR000425
Domain	LDLRA_1	TMPRSS3 PKD1 LRP2	6.14e-03	48	145	3	PS01209
Domain	LDLRA_2	TMPRSS3 PKD1 LRP2	6.50e-03	49	145	3	PS50068
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	CAND1 SLC11A2 RHBG ATP8B1 AQP1 AQP4 SLC2A1 ADD1 NEDD8 ABCG1 CLCA1 SLC15A1 SLC15A2 NIPAL2 ANO7 SLC16A8	4.68e-05	681	106	16	MM14985
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	CAND1 SLC11A2 RHBG ATP8B1 AQP1 AQP4 SLC2A1 ADD1 NEDD8 ABCG1 CLCA1 SLC15A1 SLC15A2 NIPAL2 ANO7 SLC16A8	1.17e-04	736	106	16	M27287
Pubmed	Aquaporin-4 is expressed in basolateral membranes of proximal tubule S3 segments in mouse kidney.	AQP1 AQP4 LRP2	8.68e-08	3	155	3	10662735
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA8 MYO10 DOCK9 HECTD4 BTAF1 PIGG ATG2A SLC2A1 MAPK8IP3 BAP1 FANCA GDPD5 MDN1 CELSR3 PKD1 AP1G2 GCN1 TBCD BAHCC1	5.41e-07	1105	155	19	35748872
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	DHX16 VWA8 CELSR3 AARS2 MAST3 BAHCC1 PDZD2	2.04e-06	130	155	7	12421765
Pubmed	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	GC AQP1 SLC2A1 SLC15A1 SLC15A2 CALCRL SLC16A8	3.84e-06	143	155	7	20424473
Pubmed	Genetic link between renal birth defects and congenital heart disease.	TMEM67 TBC1D32 PKD1 LRP2	7.15e-06	28	155	4	27002738
Pubmed	Aquaporin expression in blood-retinal barrier cells during experimental autoimmune uveitis.	AQP1 AQP4	1.97e-05	2	155	2	20383338
Pubmed	Importance of a small N-terminal region in mammalian peptide transporters for substrate affinity and function.	SLC15A1 SLC15A2	1.97e-05	2	155	2	11944083
Pubmed	Positive and negative regulation of water channel aquaporins in human small intestine by cholera toxin.	AQP1 AQP4	1.97e-05	2	155	2	12137754
Pubmed	Expression analysis and clinical correlation of aquaporin 1 and 4 genes in human hippocampal sclerosis.	AQP1 AQP4	1.97e-05	2	155	2	23928039
Pubmed	Peptide transporters and their roles in physiological processes and drug disposition.	SLC15A1 SLC15A2	1.97e-05	2	155	2	18668438
Pubmed	Lack of interaction between the peptidomimetic substrates captopril and cephradine.	SLC15A1 SLC15A2	1.97e-05	2	155	2	19246733
Pubmed	Human astrocytes express aquaporin-1 and aquaporin-4 in vitro and in vivo.	AQP1 AQP4	1.97e-05	2	155	2	17645239
Pubmed	Optical measurement of swelling and water transport in spinal cord slices from aquaporin null mice.	AQP1 AQP4	1.97e-05	2	155	2	11741725
Pubmed	Expression and function of water channels (aquaporins) in migrating malignant astrocytes.	AQP1 AQP4	1.97e-05	2	155	2	17549682
Pubmed	Molecular mechanism of dipeptide and drug transport by the human renal H+/oligopeptide cotransporter hPEPT2.	SLC15A1 SLC15A2	1.97e-05	2	155	2	18367661
Pubmed	Tissue distribution and thyroid hormone regulation of Pept1 and Pept2 mRNA in rodents.	SLC15A1 SLC15A2	1.97e-05	2	155	2	16202478
Pubmed	Genomic structure and refined chromosomal localization of the mouse Ptch2 gene.	MPL PTCH2	1.97e-05	2	155	2	12438747
Pubmed	TBCD may be a causal gene in progressive neurodegenerative encephalopathy with atypical infantile spinal muscular atrophy.	TBCD BAHCC1	1.97e-05	2	155	2	27928163
Pubmed	Reduced osmotic water permeability of the peritoneal barrier in aquaporin-1 knockout mice.	AQP1 AQP4	1.97e-05	2	155	2	9886922
Pubmed	Brain expression of the water channels aquaporin-1 and -4 in mice with acute liver injury, hyperammonemia and brain edema.	AQP1 AQP4	1.97e-05	2	155	2	20938728
Pubmed	Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.	STRC STRCP1	1.97e-05	2	155	2	34910522
Pubmed	Urinary KIM-1 and AQP-1 in patients with clear renal cell carcinoma: Potential noninvasive biomarkers.	AQP1 HAVCR1	1.97e-05	2	155	2	27295912
Pubmed	Aquaporin 1 and aquaporin 4 expression in human brain after subarachnoid hemorrhage and in peritumoral tissue.	AQP1 AQP4	1.97e-05	2	155	2	14753493
Pubmed	Urinary Vitamin D Binding Protein and KIM-1 Are Potent New Biomarkers of Major Adverse Renal Events in Patients Undergoing Coronary Angiography.	GC HAVCR1	1.97e-05	2	155	2	26751954
Pubmed	Aquaporin-1 and Aquaporin-4 Expression in Ependyma, Choroid Plexus and Surrounding Transition Zones in the Human Brain.	AQP1 AQP4	1.97e-05	2	155	2	36830582
Pubmed	Evaluation of aquaporins in the cerebrospinal fluid in patients with idiopathic normal pressure hydrocephalus.	AQP1 AQP4	1.97e-05	2	155	2	34597351
Pubmed	AQP1 and AQP4 Contribution to Cerebrospinal Fluid Homeostasis.	AQP1 AQP4	1.97e-05	2	155	2	30813473
Pubmed	Evidence of aquaporin involvement in human central pontine myelinolysis.	AQP1 AQP4	1.97e-05	2	155	2	24252214
Pubmed	Fetal development of membrane water channel proteins aquaporin-1 and aquaporin-4 in the human brain.	AQP1 AQP4	1.97e-05	2	155	2	16814974
Pubmed	Shifting from ependyma to choroid plexus epithelium and the changing expressions of aquaporin-1 and aquaporin-4.	AQP1 AQP4	1.97e-05	2	155	2	37975746
Pubmed	Role of aquaporins in cell migration and edema formation in human brain tumors.	AQP1 AQP4	1.97e-05	2	155	2	21784068
Pubmed	Comparison of human and monkey peptide transporters: PEPT1 and PEPT2.	SLC15A1 SLC15A2	1.97e-05	2	155	2	15981923
Pubmed	Expression of AQP1 and AQP4 in paediatric brain tumours.	AQP1 AQP4	1.97e-05	2	155	2	20965731
Pubmed	Aquaporin deletion in mice reduces intraocular pressure and aqueous fluid production.	AQP1 AQP4	1.97e-05	2	155	2	12034763
Pubmed	Expression of Aquaporin 1 and Aquaporin 4 in the Temporal Neocortex of Patients with Parkinson's Disease.	AQP1 AQP4	1.97e-05	2	155	2	26919570
Pubmed	Transient hyperosmolality modulates expression of cardiac aquaporins.	AQP1 AQP4	1.97e-05	2	155	2	22820194
Pubmed	Combined effects of aquaporin-4 and hypoxia produce age-related hydrocephalus.	AQP1 AQP4	1.97e-05	2	155	2	30293570
Pubmed	Accumulation of Astrocytic Aquaporin 4 and Aquaporin 1 in Prion Protein Plaques.	AQP1 AQP4	1.97e-05	2	155	2	32167542
Pubmed	Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.	STRC STRCP1	1.97e-05	2	155	2	11687802
Pubmed	Changes in aquaporins expression due to acute water restriction in naturally aging mice.	AQP1 AQP4	1.97e-05	2	155	2	36127549
Pubmed	Aquaporin expression in the brains of patients with or without cerebral amyloid angiopathy.	AQP1 AQP4	1.97e-05	2	155	2	21107133
Pubmed	Increased expression of water channel aquaporin 1 and aquaporin 4 in Creutzfeldt-Jakob disease and in bovine spongiform encephalopathy-infected bovine-PrP transgenic mice.	AQP1 AQP4	1.97e-05	2	155	2	16871401
Pubmed	Transport of angiotensin-converting enzyme inhibitors by H+/peptide transporters revisited.	SLC15A1 SLC15A2	1.97e-05	2	155	2	18713951
Pubmed	Aquaporin 1 and aquaporin 4 are involved in invasion of lung cancer cells.	AQP1 AQP4	1.97e-05	2	155	2	22372348
Pubmed	Changes in skeletal muscle expression of AQP1 and AQP4 in dystrophinopathy and dysferlinopathy patients.	AQP1 AQP4	1.97e-05	2	155	2	18392839
Pubmed	Expression patterns of aquaporins 1 and 4 in stroke.	AQP1 AQP4	1.97e-05	2	155	2	31912092
Pubmed	The bioactive dipeptide anserine is transported by human proton-coupled peptide transporters.	SLC15A1 SLC15A2	1.97e-05	2	155	2	20067523
Pubmed	Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels.	AQP1 AQP4	1.97e-05	2	155	2	9468475
Pubmed	Aquaporins AQP1 and AQP4 in the cerebrospinal fluid of bacterial meningitis patients.	AQP1 AQP4	1.97e-05	2	155	2	21896312
Pubmed	Role of aquaporin-4 in airspace-to-capillary water permeability in intact mouse lung measured by a novel gravimetric method.	AQP1 AQP4	1.97e-05	2	155	2	10613915
Pubmed	Uveal melanoma gene expression status post radiotherapy.	EDNRB BAP1	1.97e-05	2	155	2	24511587
Pubmed	Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice.	AQP1 AQP4	1.97e-05	2	155	2	10021464
Pubmed	Water Channels Aquaporin 4 and -1 Expression in Subependymoma Depends on the Localization of the Tumors.	AQP1 AQP4	1.97e-05	2	155	2	26115524
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	VWA8 PIGG NDUFA10 HNRNPK SCRIB DMPK GCN1	3.62e-05	202	155	7	24639526
Pubmed	RBR-type E3 ubiquitin ligase RNF144A targets PARP1 for ubiquitin-dependent degradation and regulates PARP inhibitor sensitivity in breast cancer cells.	CAND1 ADD1 SCRIB GCN1	5.83e-05	47	155	4	29212245
Pubmed	Significant enhanced expressions of aquaporin-1, -4 and -9 in the brains of various prion diseases.	AQP1 AQP4	5.90e-05	3	155	2	31814527
Pubmed	Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.	STRC STRCP1	5.90e-05	3	155	2	30801007
Pubmed	Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3).	GC LRP2	5.90e-05	3	155	2	11717447
Pubmed	Evidence against functionally significant aquaporin expression in mitochondria.	AQP1 AQP4	5.90e-05	3	155	2	16624821
Pubmed	Diagnostic value of BRCA1-associated protein-1, glucose transporter-1 and desmin expression in the discrimination between reactive mesothelial proliferation and malignant mesothelioma in tissues and effusions.	SLC2A1 BAP1	5.90e-05	3	155	2	31165505
Pubmed	A new member of the protein kinase C family, nPKC theta, predominantly expressed in skeletal muscle.	EDNRB PRKCQ	5.90e-05	3	155	2	1508194
Pubmed	Involvement of aquaporins in a mouse model of rotavirus diarrhea.	AQP1 AQP4	5.90e-05	3	155	2	25160756
Pubmed	Water influx into cerebrospinal fluid is primarily controlled by aquaporin-4, not by aquaporin-1: 17O JJVCPE MRI study in knockout mice.	AQP1 AQP4	5.90e-05	3	155	2	24231830
Pubmed	Downregulation of peptide transporters PEPT1 and PEPT2 by oxidative stress responsive kinase OSR1.	SLC15A1 SLC15A2	5.90e-05	3	155	2	25531100
Pubmed	Predictive Value of Serum Antibodies and Point Mutations of AQP4, AQP1 and MOG in A Cohort of Spanish Patients with Neuromyelitis Optica Spectrum Disorders.	AQP1 AQP4	5.90e-05	3	155	2	31752329
Pubmed	Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels.	AQP1 AQP4	5.90e-05	3	155	2	10400615
Pubmed	Expression profile and functional activity of peptide transporters in prostate cancer cells.	SLC15A1 SLC15A2	5.90e-05	3	155	2	22950754
Pubmed	Role of aquaporins in alveolar fluid clearance in neonatal and adult lung, and in oedema formation following acute lung injury: studies in transgenic aquaporin null mice.	AQP1 AQP4	5.90e-05	3	155	2	10856128
Pubmed	Structural Determinants of Oligomerization of the Aquaporin-4 Channel.	AQP1 AQP4	5.90e-05	3	155	2	26786101
Pubmed	Short-term functional adaptation of aquaporin-1 surface expression in the proximal tubule, a component of glomerulotubular balance.	AQP1 LRP2	5.90e-05	3	155	2	25270072
Pubmed	Cardiac aquaporin expression in humans, rats, and mice.	AQP1 AQP4	5.90e-05	3	155	2	16582023
Pubmed	The water channels aquaporin-1 and aquaporin-3 interact with and affect the cell polarity protein Scribble in 3D in vitro models of breast cancer.	AQP1 SCRIB	5.90e-05	3	155	2	39279492
Pubmed	Hydrophobic cluster analysis and modeling of the human Rh protein three-dimensional structures.	RHBG RHCE	5.90e-05	3	155	2	16584906
Pubmed	Immunohistochemical localization and mRNA expression of aquaporins in the macula utriculi of patients with Meniere's disease and acoustic neuroma.	AQP1 AQP4	5.90e-05	3	155	2	20461409
Pubmed	Vitamin D Regulates the Expressions of AQP-1 and AQP-4 in Mice Kidneys.	AQP1 AQP4	5.90e-05	3	155	2	30809535
Pubmed	MicroRNA 320a functions as a novel endogenous modulator of aquaporins 1 and 4 as well as a potential therapeutic target in cerebral ischemia.	AQP1 AQP4	5.90e-05	3	155	2	20628061
Pubmed	Aquaporin 1 and aquaporin 4 overexpression in bovine spongiform encephalopathy in a transgenic murine model and in cattle field cases.	AQP1 AQP4	5.90e-05	3	155	2	17868659
Pubmed	Alternate expression of PEPT1 and PEPT2 in epidermal differentiation is required for NOD2 immune responses by bacteria-derived muramyl dipeptide.	SLC15A1 SLC15A2	5.90e-05	3	155	2	31757425
Pubmed	Differential regulation of the water channel protein aquaporins in chondrocytes of human knee articular cartilage by aging.	AQP1 AQP4	5.90e-05	3	155	2	34650163
Pubmed	MGCG regulates glioblastoma tumorigenicity via hnRNPK/ATG2A and promotes autophagy.	ATG2A HNRNPK	5.90e-05	3	155	2	37460467
Pubmed	Effect of Janus kinase 3 on the peptide transporters PEPT1 and PEPT2.	SLC15A1 SLC15A2	5.90e-05	3	155	2	23934551
Pubmed	NIMA-related kinase 1 (NEK1) regulates meiosis I spindle assembly by altering the balance between α-Adducin and Myosin X.	MYO10 ADD1	5.90e-05	3	155	2	28982183
Pubmed	Identification and localization of aquaporin water channels in human salivary glands.	AQP1 AQP4	5.90e-05	3	155	2	11408278
Pubmed	Adducin-1 is essential for mitotic spindle assembly through its interaction with myosin-X.	MYO10 ADD1	5.90e-05	3	155	2	24379415
Pubmed	Expression patterns of the aquaporin gene family during renal development: influence of genetic variability.	AQP1 AQP4 LRP2	7.98e-05	19	155	3	19367412
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	CAND1 BTAF1 HACD2 SSR1 EXOC8 FANCA FZD6 AARS2 TELO2 RAB3GAP2 UTP20 SCRIB GCN1 TBCD	8.82e-05	942	155	14	31073040
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	TMEM67 DNAAF3 TBC1D32 PKD1 LRP2	8.82e-05	100	155	5	25807483
Pubmed	Evolutionary breakpoints on human chromosome 21.	NCAM2 ABCG1 TMPRSS3	9.36e-05	20	155	3	11707078
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	BTAF1 FANCA MDN1 TELO2 TBCD	1.06e-04	104	155	5	31240132
Pubmed	Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.	STRC STRCP1	1.18e-04	4	155	2	18849963
Pubmed	Molecular analysis of aquaporin genes 1 to 4 in patients with Menière's disease.	AQP1 AQP4	1.18e-04	4	155	2	21063116
Pubmed	Murine c-mpl: a member of the hematopoietic growth factor receptor superfamily that transduces a proliferative signal.	MPL SLC2A1	1.18e-04	4	155	2	8334987
Pubmed	The water permeability channels aquaporins 1-4 are differentially expressed in granulosa and theca cells of the preovulatory follicle during precise stages of human ovulation.	AQP1 AQP4	1.18e-04	4	155	2	21252246
Pubmed	The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology.	SLC15A1 SLC15A2	1.18e-04	4	155	2	12905028
Pubmed	Transport characteristics of mammalian Rh and Rh glycoproteins expressed in heterologous systems.	RHBG RHCE	1.18e-04	4	155	2	16563829
Pubmed	Role of aquaporin water channels in airway fluid transport, humidification, and surface liquid hydration.	AQP1 AQP4	1.18e-04	4	155	2	11382807
Pubmed	Tear secretion by lacrimal glands in transgenic mice lacking water channels AQP1, AQP3, AQP4 and AQP5.	AQP1 AQP4	1.18e-04	4	155	2	10870513
Pubmed	Impaired hearing in mice lacking aquaporin-4 water channels.	AQP1 AQP4	1.18e-04	4	155	2	11406631
Pubmed	Role of aquaporin water channels in eye function.	AQP1 AQP4	1.18e-04	4	155	2	12565800
Pubmed	Proton-coupled oligopeptide transporter (POT) family expression in human nasal epithelium and their drug transport potential.	SLC15A1 SLC15A2	1.18e-04	4	155	2	21366347
Interaction	GPR17 interactions	IPO8 FPGS BTAF1 PIGG HACD2 FANCA MDN1 AARS2 SLC35F6 UTP20 DGAT1 TBCD	6.88e-07	283	140	12	int:GPR17
Interaction	OPALIN interactions	KDELR2 IPO8 MED16 BTAF1 PIGG HACD2 MDN1 TELO2 UTP20 GCN1	2.06e-06	209	140	10	int:OPALIN
Interaction	GPR182 interactions	CAND1 IPO8 FPGS BTAF1 PIGG HACD2 PPOX FANCA MDN1 TELO2 UTP20 GCN1 DGAT1 TBCD	3.58e-06	455	140	14	int:GPR182
Interaction	AMACR interactions	VWA8 FPGS NDUFA10 GTPBP10 PPOX AARS2	7.11e-06	67	140	6	int:AMACR
Interaction	NPTN interactions	RPS6KA4 IPO8 NBEAL1 BTAF1 FANCA MDN1 TELO2 UTP20 GCN1 TBCD	2.52e-05	278	140	10	int:NPTN
Cytoband	2p22-p21	THUMPD2 CAPN13	3.13e-04	8	155	2	2p22-p21
Cytoband	11q12.2	MS4A18 MS4A15 MS4A8	3.16e-04	39	155	3	11q12.2
GeneFamily	CD molecules\|Membrane spanning 4-domains	MS4A18 MS4A15 MS4A8	1.19e-04	18	98	3	958
GeneFamily	CD molecules\|Tetraspanins	TSPAN31 TSPAN13 ROM1	7.49e-04	33	98	3	768
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 WDFY4	1.02e-03	9	98	2	1230
GeneFamily	Solute carriers	SLC52A1 SLC11A2 RHBG SLC30A4 SLC2A1 SLC15A1 SLC15A2 SLC16A8	1.37e-03	395	98	8	752
GeneFamily	PDZ domain containing	FRMPD2 FRMPD2B SCRIB MAST3 PDZD2	1.43e-03	152	98	5	1220
GeneFamily	Aquaporins	AQP1 AQP4	2.54e-03	14	98	2	305
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_SMG_CELL	CDC42BPG RPS6KA4 DOCK9 ZG16B FAM83E ATG2A SLC30A4 CLDN8 GDPD5 SLC15A2 SLC35F6 NIPAL2 UTP20 CALCRL SLITRK6 EDEM1	1.41e-05	775	154	16	M45713
Coexpression	GSE25088_CTRL_VS_IL4_STIM_MACROPHAGE_DN	NCAM2 H6PD MEI1 ADD1 AARS2 PLXDC2 ROM1 DGAT1	2.52e-05	200	154	8	M8007
Coexpression	GSE22589_HIV_VS_HIV_AND_SIV_INFECTED_DC_DN	MED16 EXOC8 PPOX CELSR3 SLC35F6 GCN1 ZNF367 MAST3	2.52e-05	200	154	8	M7801
ToppCell	droplet-Fat-Scat-21m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NBEAL1 SLITRK4 ATP8B1 AQP1 EXOC8 TSPAN13 CALCRL PDZD2	1.73e-07	173	155	8	f13124b4cf2ac1dc2895f90f5487d6ac681b0ba4
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOCK9 AQP1 FZD6 GDPD5 ABCG1 MCTP1 TDRD10 CALCRL	2.15e-07	178	155	8	c227da59dc7beb73f84405bf13356bdeb59d9338
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_venous_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOCK9 AQP1 FZD6 GDPD5 ABCG1 MCTP1 TDRD10 CALCRL	3.98e-07	193	155	8	84d1c1b7d3a1cb80f175527e3c89a2c3da7657f7
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NCAM2 IGSF11 CLDN8 AJAP1 LRP2 PRKCQ SLITRK6	1.78e-06	164	155	7	3caf4cdaa0164907893fea61e251fd8b5fa926e4
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Reln_(Neuron.Gad1Gad2.Cplx3-Reln)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	STAB2 LTB4R2 TMPRSS11B LRP2 SLC16A8	2.32e-06	61	155	5	06aab3f1743ced1e46d22f0310f1cdb70c7a108e
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Reln_(Neuron.Gad1Gad2.Cplx3-Reln)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	STAB2 LTB4R2 TMPRSS11B LRP2 SLC16A8	2.32e-06	61	155	5	fec6c9a4e12c260338856567bf547f914f473dbb
ToppCell	Club-club-3\|World / Class top	SLC11A2 RHBG FAM83E HID1 CAPN13 CLCA1 TSPAN13	2.44e-06	172	155	7	34fbb82a2ec77dd183cf26b38edeb7e936b707bc
ToppCell	367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	ZG16B FAM83E FHOD3 CAPN13 SLC15A1 KRTCAP3 MS4A8	2.54e-06	173	155	7	c2d973356c40e0284fd3bd7733a164b141c66008
ToppCell	367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|367C / Donor, Lineage, Cell class and subclass (all cells)	ZG16B FAM83E FHOD3 CAPN13 SLC15A1 KRTCAP3 MS4A8	2.54e-06	173	155	7	d8e965ff7e9b758876ec1521c1ccedd739e8d673
ToppCell	(03)_Secretory\|World / shred by cell type and Timepoint	RHBG FAM83E HID1 NRIP3 CLCA1 SLC15A2 TSPAN13	2.84e-06	176	155	7	cb7b1945788196ca79007f0768b6576ec885a0e5
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK9 EDNRB OR51E1 MCTP1 TSPAN13 CALCRL KIF25	3.06e-06	178	155	7	360d7a987f91d6d721487a921824057ec31a7332
ToppCell	ASK454-Epithelial\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	MS4A15 AQP4 CAPN13 DNAAF3 SLC15A2 TSPAN13 MS4A8	3.55e-06	182	155	7	ab15316cff989b61ff397a866d7ca8b49c13e981
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK9 NCAM2 HID1 FZD6 CLCA1 PRKCQ CALCRL	3.55e-06	182	155	7	d22ab50b135482915687c70e6dad29bfe2bb2c68
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	STAB2 DOCK9 AQP1 ABCG1 CLCA1 TSPAN13 CALCRL	3.55e-06	182	155	7	fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MS4A15 ALS2CL AQP4 CAPN13 FZD6 TSPAN13 PDZD2	3.81e-06	184	155	7	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DOCK9 AQP1 FZD6 GDPD5 ABCG1 TDRD10 CALCRL	3.81e-06	184	155	7	a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MS4A15 ALS2CL AQP4 CAPN13 FZD6 TSPAN13 PDZD2	3.81e-06	184	155	7	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	PND07-28-samps-Endothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MYO10 DOCK9 AQP1 ALS2CL FZD6 TSPAN13 CALCRL	4.55e-06	189	155	7	eb2f8c8a90e5e9f6697a2d13274c94f40e1973e4
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MYO10 DOCK9 AQP1 ALS2CL FZD6 TSPAN13 CALCRL	4.55e-06	189	155	7	d4a25d59d88325d3b20f4287e9b1160c82961a96
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZG16B ATP8B1 HID1 CLDN8 CLCA1 TSPAN13 ANO7	5.58e-06	195	155	7	c5f33b420c9ac14dc67fea632b8c2bc2442cbf3d
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-Goblet_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZG16B ATP8B1 HID1 CLDN8 CLCA1 TSPAN13 ANO7	5.58e-06	195	155	7	219c5d0cde7f6082755154f54db221413ec555cb
ToppCell	PCW_13-14-Endothelial\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOCK9 HID1 AQP1 GDPD5 ABCG1 TDRD10 CALCRL	5.77e-06	196	155	7	7286de29a34e13834cd6347c67a1443897fa4ade
ToppCell	critical-Epithelial-Secretory\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KDELR2 NBEAL1 SSR1 CAPN13 SLC15A2 TSPAN13 NIPAL2	5.77e-06	196	155	7	dbf14f5851c2b779a8b35e820c4584ea9096e49d
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature3_(11)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DOCK9 HID1 AQP1 SLC2A1 GDPD5 ABCG1 CALCRL	5.97e-06	197	155	7	a7922f65a8af4a773e4ce80114e4d895a594fa2f
ToppCell	10x3'2.3-week_17-19-Endothelial\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	STAB2 MYO10 DOCK9 HID1 AQP1 EDNRB CALCRL	6.17e-06	198	155	7	2630a7a6e56febe5c0b0bde70dd7292fa1650c47
ToppCell	5'-Adult-Appendix-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STAB2 DOCK9 AQP1 EDNRB FZD6 MCTP1 CALCRL	6.17e-06	198	155	7	90e85fe7a0ab376a41666dfff6c0e95b7f1c9475
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	STAB2 MYO10 DOCK9 HID1 AQP1 EDNRB CALCRL	6.17e-06	198	155	7	1e83bec16dcd60460422625f89952ff506d6be51
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	GC CAPN13 CLCA1 TMPRSS3 MS4A8 FRMPD2B DNAH9	6.37e-06	199	155	7	60919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCell	control-Epithelial-Secretory\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NBEAL1 ATP8B1 H6PD CAPN13 SLC15A2 NIPAL2 SLITRK6	6.37e-06	199	155	7	262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCell	LPS_anti-TNF-Epithelial_airway\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	GC CAPN13 CLCA1 TMPRSS3 MS4A8 FRMPD2B DNAH9	6.37e-06	199	155	7	6aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLF1 DOCK9 EDNRB CRMP1 MCTP1 TSPAN13 CALCRL	6.59e-06	200	155	7	bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPL TMEM221 GC AQP1 TSPAN13 CALCRL	1.87e-05	157	155	6	b6ecf1d8c6a465ff31cbc181e00ea88b76b38e19
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPL TMEM221 GC AQP1 TSPAN13 CALCRL	1.87e-05	157	155	6	01ad5cbaf91010e79216e1fb37b7b890618c5f28
ToppCell	LPS-antiTNF-Epithelial_airway-Club_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM83E TMPRSS11B CAPN13 CLCA1 SLC15A2 TMPRSS3	2.56e-05	166	155	6	1df4bdf7c773cbfa6c93d7a901f9cd3f3fe07a3d
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MPL GPR3 DOCK9 ATP8B1 MCTP1 CALCRL	2.56e-05	166	155	6	f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCell	LPS-antiTNF-Epithelial_airway-Club_cells-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM83E TMPRSS11B CAPN13 CLCA1 SLC15A2 TMPRSS3	2.56e-05	166	155	6	9628522e7af8f8edca733588a364ab2454ac5ca5
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDFY4 DNAAF3 PLXDC2 SLC15A2 MS4A8 DMPK	2.73e-05	168	155	6	04e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK9 AQP1 MCTP1 TDRD10 CALCRL TBCD	3.02e-05	171	155	6	b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCell	E12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DOCK9 ZNF365 TSPAN13 SCRIB CALCRL KLHDC10	3.12e-05	172	155	6	3b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCell	facs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHBDD1 FAM83E HID1 EDNRB PTCH2 NIPAL2	3.12e-05	172	155	6	f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCell	facs-Heart-LV-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHBDD1 FAM83E HID1 EDNRB PTCH2 NIPAL2	3.12e-05	172	155	6	6ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	MS4A15 AQP4 CAPN13 CELSR3 SLC15A2 TSPAN13	3.33e-05	174	155	6	edf839d79ac58921f4e788f3b2cb2ae0d6af4b9e
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)\|367C / Donor, Lineage, Cell class and subclass (all cells)	MS4A15 AQP4 CAPN13 CELSR3 SLC15A2 TSPAN13	3.33e-05	174	155	6	65539f69100db0b7d90b1b39ee15ab8281f86461
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AQP1 FZD6 GDPD5 TSPAN13 CALCRL ZNF367	3.55e-05	176	155	6	269326c2bf44a9003d95bc6dbc839f08f25737ca
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial-endothelial_cells_C\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	DOCK9 AQP1 EDNRB GDPD5 TSPAN13 CALCRL	3.66e-05	177	155	6	6da88c358b3a2e47fa3472217a38b6b00ad7b280
ToppCell	tumor_Lung-Endothelial_cells-EPCs\|tumor_Lung / Location, Cell class and cell subclass	STAB2 AQP1 CRMP1 SPTBN5 CALCRL KIF25	3.66e-05	177	155	6	f8b152c09d56a97e8c0482fb1a3964c05f9dc8c5
ToppCell	droplet-Liver-Npc-18m-Lymphocytic-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLF1 THUMPD2 KCNK7 B9D2 TSPAN13 BAHCC1	3.78e-05	178	155	6	09d2687e0d79f12e90af35fc1c0453d249cf2d19
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MS4A15 ALS2CL AQP4 FZD6 TSPAN13 PDZD2	3.90e-05	179	155	6	4f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell	AT1_cells-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	MS4A15 AQP1 ALS2CL AQP4 SLC15A2 TSPAN13	4.02e-05	180	155	6	2d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCell	facs-Lung-EPCAM-18m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM221 AQP1 ALS2CL TSPAN13 NIPAL2 CALCRL	4.02e-05	180	155	6	082c6116e0bbba8d9a3a82d14af55bdc8990c8c0
ToppCell	facs-Lung-EPCAM-18m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM221 AQP1 ALS2CL TSPAN13 NIPAL2 CALCRL	4.02e-05	180	155	6	53043d764fad9ac33ee40e356e562e759931adef
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	DOCK9 AQP1 ALS2CL FZD6 TSPAN13 CALCRL	4.15e-05	181	155	6	9cd5e5c285c2b628db9d59709af053defd7c0aff
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK9 FZD6 MCTP1 TDRD10 CALCRL TBCD	4.28e-05	182	155	6	d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FAM83E ATP8B1 HID1 CLCA1 TSPAN13 ANO7	4.55e-05	184	155	6	886d2d9bf2fe31207f17e3edc309ef44029924e1
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-goblet\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FAM83E ATP8B1 HID1 CLCA1 TSPAN13 ANO7	4.55e-05	184	155	6	936b39377eebea3961d702532779f6cd27953be7
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-Aerocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	GPR3 DOCK9 AQP1 EDNRB CRMP1 CALCRL	4.69e-05	185	155	6	7b3d30a54bec66ca6b0209c86448f4fff97ed75c
ToppCell	Club\|World / Class top	RHBG FAM83E CLCA1 SLC15A2 TSPAN13 MS4A8	4.69e-05	185	155	6	c3caf789e622ed515d143dc594158d52fdcffaef
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	HID1 OR51E1 CELSR3 TMPRSS3 CEACAM16 MS4A8	4.83e-05	186	155	6	dfd67d67c103c942de6c8acef8d81e57a9886154
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HID1 CLDN8 DNAAF3 TSPAN13 DNAH9 MAST3	4.83e-05	186	155	6	02fbb02c495e7d64c4ab50e42e5197782f2c0816
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLF1 DOCK9 EDNRB CRMP1 MCTP1 CALCRL	4.97e-05	187	155	6	f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCell	facs-Heart-LV-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO10 AQP1 EDNRB TSPAN13 CALCRL PDZD2	4.97e-05	187	155	6	1bc338c22d645a854f8d8eb8a064c441121fb673
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-endo_capillary_(2)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOCK9 AQP1 SLC2A1 GDPD5 ABCG1 CALCRL	4.97e-05	187	155	6	106f50ad85a92403037214f0e94702230284837f
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	MS4A15 ALS2CL AQP4 FZD6 TSPAN13 PDZD2	4.97e-05	187	155	6	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOCK9 AQP1 FZD6 GDPD5 ABCG1 TDRD10	5.12e-05	188	155	6	b66f1f08827dd6c48583d871f9f33ea41e48bfb2
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK9 AQP1 EDNRB CLCA1 TSPAN13 CALCRL	5.28e-05	189	155	6	ecbe079606406f47d4fc97fe1670790dda8e10de
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK9 AQP1 EDNRB CLCA1 TSPAN13 CALCRL	5.28e-05	189	155	6	e830fa0ddc3dccfaf9e88e8c416ed6aab12e3e3f
ToppCell	facs-Trachea-18m-Endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK9 AQP1 EDNRB CLCA1 TSPAN13 CALCRL	5.28e-05	189	155	6	f635f3f13bced3bcf796cf55723a2df851f973fe
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	AQP1 FZD6 GDPD5 ABCG1 TDRD10 CALCRL	5.43e-05	190	155	6	1307688255a1250fa300edf2c41f1affe31dcc98
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLF1 DOCK9 EDNRB CRMP1 MCTP1 CALCRL	5.43e-05	190	155	6	474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell	droplet-Lung-nan-21m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK9 ATP8B1 AQP1 FZD6 TSPAN13 CALCRL	5.59e-05	191	155	6	92b2faa72c184b6ae49530fd3b50848510904997
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NCAM2 ATP8B1 AQP1 FZD6 AJAP1 CALCRL	5.59e-05	191	155	6	fcdf3a747038e346a467eae8b7c293592658b53f
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	DOCK9 AQP1 FZD6 SPTBN5 GDPD5 TDRD10	5.59e-05	191	155	6	e3fc5c92491b6e334abffbf085c00a0b5fa1aed2
ToppCell	droplet-Marrow-BM-1m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC11A2 AQP1 PPOX OSGEPL1 PDIA2 ZNF367	5.59e-05	191	155	6	d78d4fbb0b8317dbf14e32182466a432abef3e93
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NCAM2 ATP8B1 AQP1 FZD6 MCTP1 CALCRL	5.59e-05	191	155	6	b270c3dd5952f56b9bdceabe13e298fe6757563b
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NCAM2 ATP8B1 HID1 AQP1 FZD6 CALCRL	5.59e-05	191	155	6	27f23c2254b610abac1a88d0fecff305addde9da
ToppCell	droplet-Lung-nan-21m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK9 ATP8B1 AQP1 FZD6 TSPAN13 CALCRL	5.59e-05	191	155	6	d0bbbf42d00165a53253c833adef65da6ec36bba
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-OPC_related-OPC\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	HAPLN2 NCAM2 NRIP3 EDNRB CALCRL SLITRK6	5.76e-05	192	155	6	5d9bc234f01c73b2531edf8960588d5b6cf260a7
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLF1 DOCK9 EDNRB CRMP1 MCTP1 CALCRL	5.76e-05	192	155	6	c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO10 DOCK9 AQP1 ALS2CL EDNRB TSPAN13	5.76e-05	192	155	6	8f20d3511dcb44445592b17d005a53da0052ae56
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO10 DOCK9 AQP1 FZD6 GDPD5 MCTP1	5.76e-05	192	155	6	5a0615fdc217554ccd611504b16e5d97628e207d
ToppCell	Entopeduncular-Neuronal\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SLITRK4 FHOD3 NRIP3 CRMP1 MCTP1 CELSR3	5.76e-05	192	155	6	4c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial-endothelial_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO10 DOCK9 AQP1 ALS2CL EDNRB TSPAN13	5.76e-05	192	155	6	0986b7900021efe2a4df84a935e7c9a0af1b0e57
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-OPC_related\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	HAPLN2 NCAM2 NRIP3 EDNRB CALCRL SLITRK6	5.76e-05	192	155	6	e6d115143ced6a0d9fe7c98acd3f730bac83f66b
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO10 DOCK9 AQP1 ALS2CL EDNRB TSPAN13	5.76e-05	192	155	6	b28d294e42b303d1db6060231d84d7b9e4d9fccf
ToppCell	(6)_Endothelial-C_(Capillary_Aerocyte_)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	DOCK9 HID1 AQP1 EDNRB AJAP1 CALCRL	5.93e-05	193	155	6	f7f2dc6aff02d096a282835094d26d12b3b73e61
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_capillary_(2)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOCK9 AQP1 SLC2A1 GDPD5 ABCG1 CALCRL	6.10e-05	194	155	6	3c31ac44e8cf4eca3ba7b8bfc05ad3e96a970956
ToppCell	15-Airway-Endothelial\|Airway / Age, Tissue, Lineage and Cell class	DOCK9 AQP1 FZD6 GDPD5 TDRD10 CALCRL	6.10e-05	194	155	6	ac0e48b0c09a7f57d30dff321b0c30a4c5e16ad9
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOCK9 AQP1 GDPD5 ABCG1 TDRD10 CALCRL	6.10e-05	194	155	6	8c88a0ddd61ad900426e312ca4ab13061c0380b8
ToppCell	15-Airway-Endothelial-Endothelial\|Airway / Age, Tissue, Lineage and Cell class	DOCK9 AQP1 FZD6 GDPD5 TDRD10 CALCRL	6.10e-05	194	155	6	f3851337a2d17f4acef2cd812a766eb0b503748b
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYO10 SLITRK4 CRMP1 AJAP1 TSPAN31 CALCRL	6.10e-05	194	155	6	920955e775617d6156c5ee8b90d2cecd01a70e12
ToppCell	356C-Epithelial_cells-Epithelial-H_(AT1)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	DOCK9 ATP8B1 AQP1 KRTCAP3 GCN1 DGAT1	6.10e-05	194	155	6	4c40d6b50675eae52c419d69e719a9223df02ae3
ToppCell	356C-Epithelial_cells-Epithelial-H_(AT1)\|356C / Donor, Lineage, Cell class and subclass (all cells)	DOCK9 ATP8B1 AQP1 KRTCAP3 GCN1 DGAT1	6.10e-05	194	155	6	99a90de637e3babec2131cdd9f05ea965d8a8f30
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	KDELR2 MYO10 FHOD3 IFITM5 KIF25 PDZD2	6.10e-05	194	155	6	292ce9021678534c9eedb367b9772a9d976208a8
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-Aerocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DOCK9 HID1 AQP1 EDNRB CRMP1 CALCRL	6.10e-05	194	155	6	54b7126b83f7482227aeaea065f504b65fa34bfe
ToppCell	facs-Heart-LA-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO10 DOCK9 AQP1 EDNRB TSPAN13 CALCRL	6.10e-05	194	155	6	33cc4f1d716cb71d54cdedbe9bbdc0d7b17c4777
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO10 DOCK9 AQP1 EDNRB FZD6 TSPAN13	6.27e-05	195	155	6	98d79f6a8a5cc86a219efe8db9f9535d7ad4c5be
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO10 DOCK9 AQP1 EDNRB FZD6 TSPAN13	6.27e-05	195	155	6	ea0627ffe1750dbdd48006d251c0ba4cadd32faf
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO10 DOCK9 AQP1 EDNRB FZD6 TSPAN13	6.27e-05	195	155	6	3b95a989adb99591b44704ff4c496a1c6cb0bb18
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FAM83E ATP8B1 HID1 CLCA1 TSPAN13 ANO7	6.27e-05	195	155	6	7ff04c45a02df01e3816f3c1d43585a93182a730
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-goblet\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZG16B ATP8B1 HID1 CLCA1 TSPAN13 ANO7	6.27e-05	195	155	6	e1fb987f13482d1fce0428413244be3621136424
Drug	3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A	MPL GPR3 STAB2 RHBG ATG2A CRMP1 MAPK8IP3 RAB3GAP2 PDZD2	5.57e-06	197	147	9	4764_UP
Drug	Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; MCF7; HT_HG-U133A	GPR3 STAB2 RHBG MATK MAPK8IP3 SPTBN5 CLCA1 RAB3GAP2 ACSBG2	6.05e-06	199	147	9	4749_UP
Drug	Myricetin [529-44-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A	MPL IL11 MED16 MATK SPTBN5 HAVCR1 LRP2 DMPK PDZD2	6.30e-06	200	147	9	4170_UP
Drug	glycylsarcosine	SLC15A1 SLC15A2	4.14e-05	2	147	2	ctd:C004194
Drug	quinaprilat	SLC15A1 SLC15A2	4.14e-05	2	147	2	ctd:C054501
Drug	moexipril	SLC15A1 SLC15A2	4.14e-05	2	147	2	ctd:C058302
Drug	Sulfadimethoxine [122-11-2]; Up 200; 12.8uM; PC3; HT_HG-U133A	IL11 STAB2 AP4E1 CLCA1 TELO2 RAB3GAP2 TBCD BAHCC1	4.20e-05	196	147	8	7400_UP
Drug	Chlorhexidine [55-56-1]; Up 200; 8uM; MCF7; HT_HG-U133A	IL11 SLC52A1 SLC30A4 EDNRB FANCA PDIA2 DMPK MAST3	4.35e-05	197	147	8	5403_UP
Drug	felodipine; Up 200; 10uM; MCF7; HG-U133A	IL11 STAB2 SLC11A2 DOCK9 ZNF365 EDNRB AJAP1 SLC15A2	4.35e-05	197	147	8	337_UP
Drug	Hydroxyzine dihydrochloride [2192-20-3]; Up 200; 9uM; MCF7; HT_HG-U133A	IL11 GPR3 STAB2 H6PD MCTP1 LRP2 NIPAL2 DMPK	4.51e-05	198	147	8	5006_UP
Drug	Meclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; HL60; HT_HG-U133A	STAB2 MED16 H6PD AP4E1 ABCG1 RAB3GAP2 ACSBG2 PRKCQ	4.51e-05	198	147	8	2424_UP
Drug	Loracarbef [121961-22-6]; Up 200; 10.8uM; MCF7; HT_HG-U133A	IL11 DOCK9 H6PD AQP1 CRMP1 NIPAL2 PDIA2 DMPK	4.51e-05	198	147	8	3532_UP
Drug	Methimazole [60-56-0]; Up 200; 35uM; MCF7; HT_HG-U133A	SLC52A1 DOCK9 ATP8B1 H6PD CRMP1 MAPK8IP3 AP1G2 KIF25	4.51e-05	198	147	8	3898_UP
Drug	(S)-propranolol hydrochloride [4199-10-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A	IL11 IPO8 DOCK9 H6PD AQP4 MAPK8IP3 PTGDR2 PDZD2	4.51e-05	198	147	8	3523_UP
Drug	Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; HL60; HG-U133A	STAB2 H6PD ALS2CL CRMP1 NIPAL2 ACSBG2 PRKCQ KIF25	4.67e-05	199	147	8	1373_UP
Drug	Timolol maleate salt [26921-17-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A	MPL STAB2 DOCK9 ATP8B1 CRMP1 RAB3GAP2 DMPK KIF25	4.67e-05	199	147	8	5280_UP
Disease	Child Development Disorders, Specific	WDFY4 SLC2A1 LRP2 TBCD	1.21e-05	29	145	4	C0085997
Disease	Child Development Deviations	WDFY4 SLC2A1 LRP2 TBCD	1.21e-05	29	145	4	C0085996
Disease	Developmental Disabilities	WDFY4 SLC2A1 LRP2 TBCD	1.39e-05	30	145	4	C0008073
Disease	autosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)	STRC STRCP1	2.40e-05	2	145	2	DOID:0110471 (implicated_via_orthology)
Disease	central pontine myelinolysis (is_marker_for)	AQP1 AQP4	2.40e-05	2	145	2	DOID:636 (is_marker_for)
Disease	sensorineural hearing loss (implicated_via_orthology)	EDNRB SLITRK6 DNAH9	1.06e-04	19	145	3	DOID:10003 (implicated_via_orthology)
Disease	QRS duration, response to sulfonylurea	DOCK9 MDN1 SLC15A1	1.92e-04	23	145	3	EFO_0005055, EFO_0007922
Disease	hydrocephalus (biomarker_via_orthology)	AQP1 AQP4	3.55e-04	6	145	2	DOID:10908 (biomarker_via_orthology)
Disease	Endotoxic shock	GC AQP1	3.55e-04	6	145	2	C0036981
Disease	Septic Shock	GC AQP1	3.55e-04	6	145	2	C0036983
Disease	Toxic Shock Syndrome	GC AQP1	3.55e-04	6	145	2	C0600327
Disease	Myotonia	SLC2A1 DMPK	3.55e-04	6	145	2	C0027125
Disease	Meckel syndrome (implicated_via_orthology)	TMEM67 TBC1D32	6.59e-04	8	145	2	DOID:0050778 (implicated_via_orthology)
Disease	retinal vein occlusion (biomarker_via_orthology)	AQP1 AQP4	6.59e-04	8	145	2	DOID:1727 (biomarker_via_orthology)
Disease	visceral heterotaxy (implicated_via_orthology)	TMEM67 DNAAF3 TBC1D32	7.99e-04	37	145	3	DOID:0050545 (implicated_via_orthology)
Disease	Spastic Paraplegia	SLC2A1 RAB3GAP2	8.44e-04	9	145	2	C0037772
Disease	glycolipid transfer protein domain-containing protein 2 measurement	ZMYND15 SLC52A1	8.44e-04	9	145	2	EFO_0801643
Disease	Meckel-Gruber syndrome	TMEM67 B9D2	1.05e-03	10	145	2	cv:C0265215
Disease	pancreatic hormone measurement	FRMPD2 FRMPD2B	1.05e-03	10	145	2	EFO_0020621
Disease	age at onset, alcohol dependence	NCAM2 DNAAF3 UTP20	1.16e-03	42	145	3	EFO_0004847, MONDO_0007079
Disease	basal cell carcinoma (is_implicated_in)	BAP1 PTCH2	1.53e-03	12	145	2	DOID:2513 (is_implicated_in)
Disease	severe acute respiratory syndrome, COVID-19	NCAM2 WDFY4 CRMP1 DNAAF3 AJAP1 PLXDC2 SLC15A1 PDZD2	1.71e-03	447	145	8	EFO_0000694, MONDO_0100096
Disease	myocardial infarction	NBEAL1 DOCK9 HECTD4 B9D2 HAVCR1 SLC15A1 PDZD2	1.78e-03	350	145	7	EFO_0000612
Disease	IGFBP-1 measurement	MYO10 IGSF11	1.81e-03	13	145	2	EFO_0005118
Disease	Metabolic Bone Disorder	GC LRP2	2.10e-03	14	145	2	C0005944
Disease	Meckel-Gruber syndrome	TMEM67 B9D2	2.41e-03	15	145	2	C0265215
Disease	Osteopenia	GC LRP2	2.41e-03	15	145	2	C0029453
Disease	brain edema (biomarker_via_orthology)	AQP1 AQP4	2.41e-03	15	145	2	DOID:4724 (biomarker_via_orthology)
Disease	refractive error, age at onset, Myopia	FRMPD2 SSR1 MEI1 FRMPD2B MEX3B	2.71e-03	193	145	5	EFO_0004847, HP_0000545, MONDO_0004892
Disease	amyloid-beta measurement, Alzheimer's disease biomarker measurement	HAVCR1 PLXDC2	2.75e-03	16	145	2	EFO_0005194, EFO_0006514
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	TMEM67 PKD1	2.75e-03	16	145	2	DOID:0110861 (implicated_via_orthology)
Disease	uric acid measurement	CDC42BPG SLC52A1 RPS6KA4 HECTD4 AQP1 CLDN8 FANCA SLC15A2 LRP2	3.29e-03	610	145	9	EFO_0004761
Disease	Meckel syndrome type 1	TMEM67 B9D2	3.48e-03	18	145	2	C3714506
Disease	diabetes mellitus (biomarker_via_orthology)	AQP1 AQP4	3.88e-03	19	145	2	DOID:9351 (biomarker_via_orthology)
Disease	hydrocephalus (implicated_via_orthology)	TMEM67 ADD1	3.88e-03	19	145	2	DOID:10908 (implicated_via_orthology)
Disease	factor VIII measurement, Ischemic stroke	STAB2 HECTD4	3.88e-03	19	145	2	EFO_0004630, HP_0002140
Disease	serum homoarginine measurement	CRMP1 SLC15A1	4.30e-03	20	145	2	EFO_0005421
Disease	serum carcinoembryonic antigen measurement	FAM83E GC	4.30e-03	20	145	2	EFO_0005760
Disease	dilated cardiomyopathy	FHOD3 PKD1	4.30e-03	20	145	2	EFO_0000407
Disease	Osteogenesis imperfecta	KDELR2 IFITM5	4.74e-03	21	145	2	cv:C0029434
Disease	response to ketamine	CRMP1 DNAAF3 PDZD2	4.81e-03	69	145	3	EFO_0009748

Protein segments in the cluster

Peptide	Gene	Start	Entry
SLIKLGLERFHGVGI	ACSBG2	96	Q5FVE4
VLLLLSLGDTIGEHH	ALS2CL	166	Q60I27
AGHGLLVELIITFQL	AQP4	156	P55087
GIHGIALLSELADLA	BAHCC1	1331	Q9P281
RITSHIGIGLLIGLL	ABCG1	426	P45844
LIHIAGILARIASVE	TBC1D32	546	Q96NH3
HLNSTGVLLEVGGVL	BRD8	226	Q9H0E9
NVTLVVHGLSGELLA	CEACAM16	36	Q2WEN9
GLQITLGLLALQHFE	FAM220BP	231	B1ANY3
ILGEASGLAVHQIIT	AJAP1	271	Q9UKB5
AIGLSVALGHLLAID	AQP1	171	P29972
ERHHGILLGTITLIT	AP1G2	186	O75843
VISTGLLHLAEDGVL	BAP1	556	Q92560
ASLALGDLLHIVIDI	EDNRB	141	P24530
ALVDLTGGVITNIHL	CAPN13	191	Q6MZZ7
GNVVLLLKSLGIHDL	DHX16	761	O60231
VGALTEQAGLLLHVA	DGAT1	156	O75907
LEVAGQLGSLHLLLT	ATG2A	276	Q2TAZ0
VVLILLSAGLAIGHA	ATP8B1	346	O43520
LRLHIIEIIGNEGLL	AP4E1	1076	Q9UPM8
HILVGLEDGKLIVVG	NBEAL1	2641	Q6ZS30
LALGTEEGLFVIHLR	CDC42BPG	1106	Q6DT37
LGLVLLVEAAAVLIG	SLC16A8	381	O95907
LGIHQLLAEGVLSAA	ANO7	276	Q6IWH7
GLALHLIEAVEAISL	RAB3GAP2	1376	Q9H2M9
LVLLISGGHCLLALV	OSGEPL1	166	Q9H4B0
HLATLGGNLLILVAV	OR10AC1	36	Q8NH08
AEIILGLQFLHSKGI	PRKCQ	486	Q04759
GQVLFRHLAGLAELL	MDN1	3136	Q9NU22
LGLILAAVVEVGALL	GPR62	16	Q9BZJ7
ENLVRLLGVILHQGL	MATK	286	P42679
LEEGEGHLVLLVTLT	MCTP1	571	Q6DN14
LTETVVLHRGQLLGL	MAPK8IP3	1171	Q9UPT6
ILGGSVLHLVLALRG	NEDD8	61	Q15843
GELRETLILITNGLH	HAPLN2	76	Q9GZV7
LGTLHQLGIVVGILI	SLC2A1	156	P11166
GLLVVAHLLALGLGA	KCNK7	11	Q9Y2U2
LLALLSLGEVGHHID	CAND1	836	Q86VP6
TIVHGVLINGLISAL	HTD2	81	P86397
IRAAHAILGGLHLTL	IL11	171	P20809
TQLLHLGLTQGLIER	KLHDC10	426	Q6PID8
TTLAALLGVIILEGL	LDAF1	76	Q96B96
IHSLAIVESGILLVL	OR51B4	101	Q9Y5P0
GLIVIISAIGLDSLL	OR51E1	201	Q8TCB6
GDELLVINGHLLVGL	PDZD2	381	O15018
VSRLLAGILHLGNIE	MYO10	326	Q9HD67
LAARLGVVTGLHLAE	SLC11A2	121	P49281
IAGLLVLALCHIAVG	GDPD5	101	Q8WTR4
VQLLGDLLFHISGVT	GCN1	1836	Q92616
LVLELLRGGELLEHI	RPS6KA4	481	O75676
IIFSNGRDLLIGDIH	LRP2	396	P98164
EDGILVLSRHTLGLA	PDIA2	41	Q13087
GNALIILAIITDSHL	OR1I1	41	O60431
HFLGQLLGIAIRADV	HECTD4	3701	Q9Y4D8
QLGDIGLDLTFIIHA	EXOC8	531	Q8IYI6
VLLHGLASLLGLVEN	PTGDR2	36	Q9Y5Y4
LDLLLGVHQELGASE	DMPK	26	Q09013
DLLAGLGLVLHFAAV	GPR3	86	P46089
ALEHLLTTGQGVVLE	NDUFA10	146	O95299
LALVGIDSHGKLSVL	MED16	441	Q9Y2X0
IQVGGLIRGHFLLIL	MEI1	876	Q5TIA1
VGLSLLLAGIISLNH	FZD6	381	O60353
HLIGGIKSFGLDRII	FBH1	771	Q8NFZ0
LLLLSLHGVAASLEV	IGSF11	11	Q5DX21
IHLDLKLIADVGLVG	GTPBP10	141	A4D1E9
NHFLVGLLLREVGTA	DOCK9	1111	Q9BZ29
ELDVLLLGSVDGRHL	DNAAF3	46	Q8N9W5
VLLLTTHVGGLGLNL	BTAF1	1701	O14981
TEGLIFQEVLHLLRG	FRMPD2B	151	Q6IN97
EGLIFQEVLHLLRGA	FRMPD2	1141	Q68DX3
VLGLAALAVHLGESR	FANCA	781	O15360
TGALLEILHCAIGIV	HACD2	86	Q6Y1H2
DLALGTQLAGVHRLL	FHOD3	36	Q2V2M9
LVLGLVLLRLGLHGV	EDEM1	6	Q92611
LLLLGGLVRSVAHEA	HAS1	511	Q92839
TVQILIGLIHLGFGS	MS4A15	76	Q8N5U1
LGVSAIQILIGLTHI	MS4A18	156	Q3C1V0
TLGAIQIIIGLAHIG	MS4A8	71	Q9BY19
DLITHINGESVLGLV	MAST3	1001	O60307
LGLVVTGALHLARLA	IFITM5	101	A6NNB3
LVTGSLHLVGGVLKL	FPGS	566	Q05932
GFLGQLHVVEGLLKT	DNAH9	441	Q9NYC9
ALGVAELLFLLGIHR	CELSR3	2581	Q9NYQ7
ELQGHVSIILLGATG	H6PD	21	O95479
TAAGGTVHLEIGLLL	B9D2	151	Q9BPU9
HVVLSLIGLALIALG	SLC15A1	121	P46059
LGGQVVHTVLSLIGL	SLC15A2	136	Q16348
LTGDLSHLAAIVILL	KDELR2	6	P33947
AVALVHGVGLLATDL	PRRT3	576	Q5FWE3
IIGHGLSIASLLISL	CALCRL	146	Q16602
LGAVILVHAENGDLI	CRMP1	191	Q14194
VGLALILVGHVNLLL	KRTCAP3	21	Q53RY4
ILVGHVNLLLGAVLH	KRTCAP3	26	Q53RY4
VNLLLGAVLHGTVLR	KRTCAP3	31	Q53RY4
AIGDSILNITGDLIH	PKD1	2711	P98161
DGALHVIGSLAEILL	IPO8	431	O15397
IGHILVERDINGTLL	TMEM67	131	Q5HYA8
GNLLIILAISIDSHL	OR1M1	41	Q8NGA1
LLLVVAVTGGFLHSV	OR4A8	141	P0C604
GAHFLGGVEIILLTV	OR4C3	101	Q8NH37
IEAHIALRTGGIIEL	MEX3B	221	Q6ZN04
GQIEHLVITLGSLRL	NRIP3	166	Q9NQ35
IGVLEHIGRVVELQL	SLITRK4	196	Q8IW52
LGRQHGILNSLEIVL	UTP20	1091	O75691
GLILLLSQIFHVGIN	RHBDD1	11	Q8TEB9
GLGLLVIVGLHQLLE	SSR1	216	P43307
VGFLEHIGRILDLQL	SLITRK6	201	Q9H5Y7
LHRGLVTLLTGEIVD	FAM83E	261	Q2M2I3
VLHLALADGAVLLLT	LTB4R2	61	Q9NPC1
LALIHSVRGEAGLLV	TDRD10	186	Q5VZ19
LVGLLALSHGQLHVE	SERPINA4	11	P29622
IHLFGVLLAILGNLV	NIPAL2	46	Q9H841
ELRLLIHQSLAGGII	HNRNPK	146	P61978
SILRVSLGGHTLILI	PRR23B	86	Q6ZRT6
ALTVLTLLGLLHGLV	PTCH2	1091	Q9Y6C5
VILSLILHLADSVAG	HAVCR1	6	Q96D42
SEILRFLQHGTLVGL	HID1	721	Q8IV36
TLHAGLIIGILILVL	PLXDC2	451	Q6UX71
GLGKTVEVLALILTH	SHPRH	376	Q149N8
LLGEDQLVLGRLAHT	TELO2	716	Q9Y4R8
LGLTHGEAVQLLRSV	SCRIB	1166	Q14160
LAALAGVLGALLEHR	KIF25	296	Q9UIL4
VHQAGVLGGLVEVLL	STRC	131	Q7RTU9
GTHLLRTGAVGDLVI	AARS2	751	Q5JTZ9
DGIHLLRLLELISGE	SPTBN5	86	Q9NRC6
VLILRNHGLVSVGES	ADD1	296	P35611
AHILLTAGIIFIITG	CLDN8	116	P56748
SSVFILILHLLEGAL	CLCA1	6	A8K7I4
IIALILALAIGLGIH	TMPRSS3	56	P57727
EQTHRSILLGLLLGA	PPOX	191	P50336
DHEITGLRVSVGLLL	ZG16B	71	Q96DA0
LFLIALVGLIGAVKH	TSPAN13	56	O95857
GLLGEITYIVLLVLH	RHCE	336	P18577
GLGVAALLLILVVTD	NCAM2	706	O15394
AILGVTIGLLVHFLA	TMPRSS11B	26	Q86T26
VLLEHLQDLAGTLGS	ROM1	256	Q03395
LGRLVLTHLLVALFG	SLC52A1	6	Q9NWF4
LGALLGVLVAGLATH	RHBG	351	Q9H310
LVIVQGHLVSEGVLL	WDFY4	2396	Q6ZS81
VLLLAVAFGHALERG	GC	6	P02774
IDALHGEQLGLFLRT	nan	106	Q6ZSV7
RVLHVGGTIVLLLSE	THUMPD2	396	Q9BTF0
LLLIAVAGLVGAVNH	TSPAN31	56	Q12999
IIQGDIIASNGLLHI	STAB2	486	Q8WWQ8
TALHLVLGLSAVLGL	MPL	496	P40238
THLFILEGLADQGLR	nan	276	Q6ZUG5
RGVLNLIESLIEGHF	SLF1	411	Q9BQI6
HALQILGFLILLIGT	SLC35F6	316	Q8N357
VHALGDLVQSVGVLI	SLC30A4	276	O14863
ILGSGTLVLVAVLTH	TMEM221	156	A6NGB7
VHQAGVLGGLVEVLL	STRCP1	131	A6NGW2
HVLLGLVVSLGGLTE	TBCD	981	Q9BTW9
GKLTIIDLLTEHLLG	ZNF365	186	Q70YC4
LHGALALIELANLTG	ZNF367	331	Q7RTV3
DLLILLGTAGHVLSL	PIGG	551	Q5H8A4
VLLDGIHRVNAGTLA	VWA8	511	A3KMH1
SVLRVSLGGHTLIVI	PRR23C	86	Q6ZRP0
CLLLVTDEHGTILGI	ZMYND15	206	Q9H091
LENLFGIIASVLHLG	MYO1H	266	Q8N1T3