Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GTPase activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D24 ARHGAP18 TBC1D3I TBC1D3G DEPDC1B TBC1D3K TBC1D3F	1.11e-09	279	118	14	GO:0005096
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	2.97e-09	11	118	5	GO:0004523
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	1.27e-08	14	118	5	GO:0003964
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RAPGEF1 DENND2D TBC1D3C TBC1D3B TBC1D24 ARHGAP18 TBC1D3I TBC1D3G DEPDC1B TBC1D3K TBC1D3F	5.07e-08	507	118	16	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RAPGEF1 DENND2D TBC1D3C TBC1D3B TBC1D24 ARHGAP18 TBC1D3I TBC1D3G DEPDC1B TBC1D3K TBC1D3F	5.07e-08	507	118	16	GO:0030695
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 POLK ERVK-11	8.86e-08	38	118	6	GO:0034061
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	1.25e-07	21	118	5	GO:0035613
GeneOntologyMolecularFunction	enzyme activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D24 PDCD5 SUZ12 ARHGAP18 TBC1D3I TBC1D3G DEPDC1B TBC1D3K TBC1D3F	1.59e-06	656	118	16	GO:0008047
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	2.48e-06	37	118	5	GO:0016891
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18	2.48e-06	37	118	5	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18	2.84e-06	38	118	5	GO:0070001
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 ERVK-7 ERVK-10 AGO1 ERVK-8 ERVK-11	7.33e-06	79	118	6	GO:0004521
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	7.47e-06	46	118	5	GO:0016893
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	ERVK-6 TTF2 SETX ERVK-7 ERVK-10 THAP9 ERVK-8 POLK ERVK-11	2.59e-05	262	118	9	GO:0140097
GeneOntologyMolecularFunction	nucleotidyltransferase activity	ERVK-6 TUT7 ERVK-7 ERVK-10 ERVK-8 POLK ERVK-11	3.36e-05	152	118	7	GO:0016779
GeneOntologyMolecularFunction	RNA nuclease activity	ERVK-6 ERVK-7 ERVK-10 AGO1 ERVK-8 ERVK-11	1.58e-04	136	118	6	GO:0004540
GeneOntologyMolecularFunction	endonuclease activity	ERVK-6 ERVK-7 ERVK-10 AGO1 ERVK-8 ERVK-11	1.58e-04	136	118	6	GO:0004519
GeneOntologyMolecularFunction	group III metabotropic glutamate receptor activity	GRM6 GRM7	2.06e-04	4	118	2	GO:0001642
GeneOntologyMolecularFunction	molecular function activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B PTK2 TBC1D24 CSPG5 PDCD5 SUZ12 ARHGAP18 TBC1D3I TBC1D3G DEPDC1B TBC1D3K TBC1D3F	3.27e-04	1233	118	18	GO:0140677
GeneOntologyMolecularFunction	enzyme regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RAPGEF1 DENND2D GRM7 TBC1D3C TBC1D3B TBC1D24 PDCD5 SUZ12 ARHGAP18 TBC1D3I TBC1D3G DEPDC1B TBC1D3K TBC1D3F	6.38e-04	1418	118	19	GO:0030234
GeneOntologyMolecularFunction	G protein-coupled glutamate receptor activity	GRM6 GRM7	1.21e-03	9	118	2	GO:0098988
GeneOntologyMolecularFunction	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity	GRM6 GRM7	1.21e-03	9	118	2	GO:0001640
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	ERVK-6 TTF2 SETX TUT7 ERVK-7 ERVK-10 THAP9 AGO1 ERVK-8 POLK ERVK-11	1.54e-03	645	118	11	GO:0140640
GeneOntologyMolecularFunction	nuclease activity	ERVK-6 ERVK-7 ERVK-10 AGO1 ERVK-8 ERVK-11	2.52e-03	231	118	6	GO:0004518
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA1 ABCA10 ABCD3	3.04e-03	49	118	3	GO:0140359
GeneOntologyBiologicalProcess	activation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RAPGEF1 TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	8.99e-13	109	114	12	GO:0090630
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-7 ERVK-10 THAP9 ERVK-8 ERVK-11	4.15e-11	13	114	6	GO:0015074
GeneOntologyBiologicalProcess	regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RRP1B RAPGEF1 TBC1D3C TBC1D3B PTK2 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	4.91e-09	335	114	14	GO:0043087
GeneOntologyBiologicalProcess	positive regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RAPGEF1 TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.09e-08	244	114	12	GO:0043547
GeneOntologyBiologicalProcess	DNA synthesis involved in DNA repair	ERVK-6 ERVK-7 ERVK-10 ERVK-8 POLK ERVK-11	2.54e-07	48	114	6	GO:0000731
GeneOntologyBiologicalProcess	positive regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RAPGEF1 TBC1D3C TBC1D3B PDCD5 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	3.90e-06	499	114	13	GO:0051345
GeneOntologyBiologicalProcess	positive regulation of catalytic activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RAPGEF1 TBC1D3C ADCY2 TBC1D3B PTK2 FCER1A PDCD5 TBC1D3I TBC1D3G IL23R TBC1D3K TBC1D3F	4.89e-05	1028	114	17	GO:0043085
GeneOntologyBiologicalProcess	RNA-templated DNA biosynthetic process	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	9.73e-05	83	114	5	GO:0006278
GeneOntologyBiologicalProcess	regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RRP1B RAPGEF1 TBC1D3C TBC1D3B PTK2 PDCD5 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	9.90e-05	878	114	15	GO:0051336
GeneOntologyBiologicalProcess	positive regulation of molecular function	TBC1D3E TBC1D3 TBC1D3H TBC1D3L ANK2 TBC1D3D RAPGEF1 TBC1D3C ADCY2 TBC1D3B PTK2 PYHIN1 FCER1A PDCD5 TBC1D3I NEUROG2 TBC1D3G IL23R TBC1D3K TBC1D3F	1.04e-04	1430	114	20	GO:0044093
Domain	TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D24 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	3.48e-15	49	108	11	SM00164
Domain	RabGAP-TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D24 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	8.93e-15	53	108	11	PF00566
Domain	TBC_RABGAP	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D24 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.39e-14	55	108	11	PS50086
Domain	Rab-GTPase-TBC_dom	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D24 TBC1D3I TBC1D3G TBC1D3K TBC1D3F	1.39e-14	55	108	11	IPR000195
Domain	GPCR_3_mtglu_rcpt	GRM6 GRM7	9.07e-04	8	108	2	IPR000162
Domain	Kinesin_motor_CS	KIF2A KIF13A KIF2C	1.71e-03	41	108	3	IPR019821
Domain	ABC_transporter_CS	ABCA1 ABCA10 ABCD3	1.83e-03	42	108	3	IPR017871
Domain	Kinesin-like_fam	KIF2A KIF13A KIF2C	1.96e-03	43	108	3	IPR027640
Domain	KINESIN_MOTOR_1	KIF2A KIF13A KIF2C	2.10e-03	44	108	3	PS00411
Domain	-	KIF2A KIF13A KIF2C	2.10e-03	44	108	3	3.40.850.10
Domain	Kinesin_motor_dom	KIF2A KIF13A KIF2C	2.10e-03	44	108	3	IPR001752
Domain	Kinesin	KIF2A KIF13A KIF2C	2.10e-03	44	108	3	PF00225
Domain	KINESIN_MOTOR_2	KIF2A KIF13A KIF2C	2.10e-03	44	108	3	PS50067
Domain	KISc	KIF2A KIF13A KIF2C	2.10e-03	44	108	3	SM00129
Domain	ABC_A	ABCA1 ABCA10	2.11e-03	12	108	2	IPR026082
Domain	NCD3G	GRM6 GRM7	2.48e-03	13	108	2	PF07562
Domain	GPCR_3_9-Cys_dom	GRM6 GRM7	2.48e-03	13	108	2	IPR011500
Domain	ABC_tran	ABCA1 ABCA10 ABCD3	2.69e-03	48	108	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCA1 ABCA10 ABCD3	2.69e-03	48	108	3	PS50893
Domain	ABC_TRANSPORTER_1	ABCA1 ABCA10 ABCD3	2.86e-03	49	108	3	PS00211
Domain	GPCR_3_CS	GRM6 GRM7	2.88e-03	14	108	2	IPR017979
Domain	ABC_transporter-like	ABCA1 ABCA10 ABCD3	3.03e-03	50	108	3	IPR003439
Domain	AT_hook	PRR12 KMT2A	3.77e-03	16	108	2	PF02178
Domain	ALPHA_CA_2	CA14 PTPRZ1	4.26e-03	17	108	2	PS51144
Domain	Carb_anhydrase	CA14 PTPRZ1	4.26e-03	17	108	2	PF00194
Domain	Carb_anhydrase	CA14 PTPRZ1	4.26e-03	17	108	2	SM01057
Domain	-	CA14 PTPRZ1	4.26e-03	17	108	2	3.10.200.10
Domain	Carbonic_anhydrase_a	CA14 PTPRZ1	4.26e-03	17	108	2	IPR001148
Domain	Myosin_tail_1	MYH14 CGNL1	4.77e-03	18	108	2	PF01576
Domain	Myosin_tail	MYH14 CGNL1	4.77e-03	18	108	2	IPR002928
Domain	Myosin-like_IQ_dom	MYH14 ASPM	5.31e-03	19	108	2	IPR027401
Domain	-	MYH14 ASPM	5.31e-03	19	108	2	4.10.270.10
Pathway	WP_17Q12_COPY_NUMBER_VARIATION_SYNDROME	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K	2.46e-09	99	75	9	M46448
Pubmed	TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	5.15e-28	11	120	11	16863688
Pubmed	DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.	TBC1D3E TBC1D3 TBC1D3H TBC1D3D TBC1D3B TBC1D3G TBC1D3F	7.25e-09	74	120	7	16625196
Pubmed	PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.	TBC1D3 TBC1D3D TBC1D3F	1.60e-07	4	120	3	12359748
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-10	1.60e-07	4	120	3	10469592
Pubmed	Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.	TBC1D3 TBC1D3D TBC1D3F	1.60e-07	4	120	3	8406013
Pubmed	The Tre2 (USP6) oncogene is a hominoid-specific gene.	TBC1D3 TBC1D3D TBC1D3C	3.99e-07	5	120	3	12604796
Pubmed	Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.	TBC1D3 TBC1D3D TBC1D3F	3.99e-07	5	120	3	8471161
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-7 ERVK-18	3.99e-07	5	120	3	12629516
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-11	9.45e-07	94	120	6	21542922
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PRPF31 SHROOM3 SETX CCDC137 GALNT3 RRP1B NACA DENND2D ESF1 PRR12 RFTN1 PAXBP1 ABCD3 KMT2A KIF2A SUZ12 KIF2C ATP5F1C	3.90e-06	1497	120	18	31527615
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PRPF31 TTF2 SETX TUT7 NACA IDH3B PTK2 ESF1 UPF2 MYH14 MCM3AP ASPM ABCD3 KIF2A RPL22L1 KIF2C ATP5F1C	4.18e-06	1353	120	17	29467282
Pubmed	Translocation (4;11)(p12;q23) with rearrangement of FRYL and MLL in therapy-related acute myeloid leukemia.	FRYL KMT2A	1.18e-05	2	120	2	17854671
Pubmed	Efficient mitosis in human cells lacking poleward microtubule flux.	KIF2A KIF2C	1.18e-05	2	120	2	16243029
Pubmed	An ADAM12 and FAK positive feedback loop amplifies the interaction signal of tumor cells with extracellular matrix to promote esophageal cancer metastasis.	ADAM12 PTK2	1.18e-05	2	120	2	29476791
Pubmed	Ternary complex of Kif2A-bound tandem tubulin heterodimers represents a kinesin-13-mediated microtubule depolymerization reaction intermediate.	KIF2A KIF13A	1.18e-05	2	120	2	29980677
Pubmed	AF4p12, a human homologue to the furry gene of Drosophila, as a novel MLL fusion partner.	FRYL KMT2A	1.18e-05	2	120	2	16061630
Pubmed	The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization.	KIF13A KIF2C	1.18e-05	2	120	2	21873978
Pubmed	TRAK2, a novel regulator of ABCA1 expression, cholesterol efflux and HDL biogenesis.	ABCA1 TRAK2	1.18e-05	2	120	2	28655204
Pubmed	Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity.	ERVK-6 ERVK-18	1.18e-05	2	120	2	11672541
Pubmed	The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK.	KIF2A KIF2C	1.18e-05	2	120	2	15302853
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SETX TUT7 NACA PTK2 ESF1 PRR12 UPF2 ABCD3 KMT2A KIF2A ATP5F1C	1.65e-05	650	120	11	38777146
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-10 ERVK-18 ERVK-11	3.15e-05	18	120	3	18664271
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	PRPF31 TTF2 CCDC137 ANK2 RRP1B NACA PSMD12 TRMT6 UPF2 PDCD5 ASPM UNC13C RPL22L1	3.23e-05	971	120	13	33306668
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ATRN MCM3AP PACS2 TRAK2 MAST3	3.30e-05	105	120	5	9628581
Pubmed	Ras regulates kinesin 13 family members to control cell migration pathways in transformed human bronchial epithelial cells.	KIF2A KIF2C	3.53e-05	3	120	2	24240690
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-6 ERVK-18	3.53e-05	3	120	2	10516026
Pubmed	Diversity of human copy number variation and multicopy genes.	TBC1D3E TBC1D3G	3.53e-05	3	120	2	21030649
Pubmed	Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.	ERVK-6 ERVK-11	3.53e-05	3	120	2	9971820
Pubmed	Ras transformation uncouples the kinesin-coordinated cellular nutrient response.	KIF2A KIF2C	3.53e-05	3	120	2	25002494
Pubmed	Prospective tracing of MLL-FRYL clone with low MEIS1 expression from emergence during neuroblastoma treatment to diagnosis of myelodysplastic syndrome.	FRYL KMT2A	3.53e-05	3	120	2	18195096
Pubmed	The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells.	KIF2A KIF2C	3.53e-05	3	120	2	17538014
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	PRPF31 SHROOM3 SETX PSMD12 ABCD3 ARHGAP18 IGSF3	5.21e-05	277	120	7	30745168
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	PRPF31 CCDC137 RRP1B TUT7 NACA ESF1 UPF2 ASPM KIF2A SUZ12 KIF2C	6.69e-05	759	120	11	35915203
Pubmed	USP21 deubiquitylates Nanog to regulate protein stability and stem cell pluripotency.	USP21 NANOGP1	7.05e-05	4	120	2	29263902
Pubmed	The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia.	KMT2A SUZ12	7.05e-05	4	120	2	22469984
Pubmed	Identification of a structurally distinct CD101 molecule encoded in the 950-kb Idd10 region of NOD mice.	TTF2 IGSF3	7.05e-05	4	120	2	12765969
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-10	7.05e-05	4	120	2	7983737
Pubmed	Distribution of group-III metabotropic glutamate receptors in the retina.	GRM6 GRM7	7.05e-05	4	120	2	17311335
Pubmed	Combined deficiency of Senataxin and DNA-PKcs causes DNA damage accumulation and neurodegeneration in spinal muscular atrophy.	SETX GRM7	1.17e-04	5	120	2	30010942
Pubmed	Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.	ERVK-6 ERVK-7	1.17e-04	5	120	2	11401426
Pubmed	A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis.	TUT7 UPF2	1.17e-04	5	120	2	30617251
Pubmed	The deubiquitinase USP21 maintains the stemness of mouse embryonic stem cells via stabilization of Nanog.	USP21 NANOGP1	1.17e-04	5	120	2	27886188
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	RRP1B TUT7 NACA PSMD12 ESF1 TRMT6 ABCD3 KIF2A ATP5F1C	1.23e-04	547	120	9	37267103
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	RRP1B TUT7 ESF1 RPRD1B MYH14 ABCD3 SMARCD1 KIF2A	1.51e-04	440	120	8	34244565
Pubmed	Pias1 interaction and sumoylation of metabotropic glutamate receptor 8.	GRM6 GRM7	1.75e-04	6	120	2	16144832
Pubmed	RACK1 Promotes Self-Renewal and Chemoresistance of Cancer Stem Cells in Human Hepatocellular Carcinoma through Stabilizing Nanog.	USP21 NANOGP1	1.75e-04	6	120	2	30809310
Pubmed	Progression of the pluripotent epiblast depends upon the NMD factor UPF2.	NANOGP1 UPF2	1.75e-04	6	120	2	36255229
Pubmed	Protein chip analysis of pluripotency-associated proteins in NIH3T3 fibroblast.	PTK2 NANOGP1	1.75e-04	6	120	2	19701907
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PRPF31 SHROOM3 SETX COBLL1 FRYL KMT2A KIF2A CGNL1 KIF13A DEPDC1B KIF2C	2.01e-04	861	120	11	36931259
Pubmed	Metabotropic glutamate receptor subtype 7 ablation causes deficit in fear response and conditioned taste aversion.	GRM6 GRM7	2.45e-04	7	120	2	9920659
Pubmed	Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3-based peptide mimetic.	KMT2A SUZ12	2.45e-04	7	120	2	21135039
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	SETX ANK2 RRP1B COBLL1 TUT7 NACA TRMT6 PAXBP1 UPF2 MYH14 PDCD5 MCM3AP KMT2A SMARCD1	2.79e-04	1371	120	14	36244648
Pubmed	All kinesin superfamily protein, KIF, genes in mouse and human.	KIF2A KIF13A KIF2C	2.86e-04	37	120	3	11416179
Pubmed	TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation.	KIF2A KIF2C	3.26e-04	8	120	2	26323690
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	MROH9 CCDC137 FRYL GPC6 USH1C ADCY2 USP21 AGO1 MYH14 CBX6 ASPM ARHGAP18 IL23R	3.68e-04	1242	120	13	30973865
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	SETX ICA1 TUT7 FRYL ESF1 RPRD1B PAXBP1 KCNJ1 KIF2A POLK KIF13A KIF2C	3.80e-04	1084	120	12	11544199
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	GALNT3 NBEA IDH3B OR52P1 ADCY2 ESF1 RPRD1B SMARCD1 IGSF3	3.82e-04	638	120	9	31182584
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	PRPF31 RRP1B NACA PSMD12 IDH3B ESF1 RPRD1B TRMT6 PAXBP1 MYH14 ABCD3 KIF2A SUZ12 ATP5F1C	4.11e-04	1425	120	14	30948266
Pubmed	Discovery of tissue-specific exons using comprehensive human exon microarrays.	ANK2 RAPGEF1	4.18e-04	9	120	2	17456239
Pubmed	ZRANB1 Is an EZH2 Deubiquitinase and a Potential Therapeutic Target in Breast Cancer.	USP49 SUZ12	4.18e-04	9	120	2	29669287
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ANK2 NBEA IDH3B TBC1D24 AGO1 UPF2 MYH14 PTPRZ1 ABCD3 KMT2A PACS2 KIF2A CGNL1 ATP5F1C	4.28e-04	1431	120	14	37142655
Pubmed	Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.	TBC1D3 TBC1D24 TBC1D3F	4.47e-04	43	120	3	19077034
Pubmed	Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.	NANOGP1 KMT2A SUZ12	4.78e-04	44	120	3	24183668
Pubmed	Combinatorial CRISPR screen identifies fitness effects of gene paralogues.	IDH3B FAM50B PAXBP1 ASPM KMT2A	4.81e-04	186	120	5	33637726
Pubmed	Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors.	GRM6 GRM7	5.22e-04	10	120	2	9069281
Pubmed	Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.	KMT2A SMARCD1	5.22e-04	10	120	2	12665591
Pubmed	Shifts in the vascular endothelial growth factor isoforms result in transcriptome changes correlated with early neural stem cell proliferation and differentiation in mouse forebrain.	SUZ12 NEUROG2	5.22e-04	10	120	2	24124161
Pubmed	ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency.	KMT2A SUZ12	5.22e-04	10	120	2	20569692
Pubmed	Intersubspecific subcongenic mouse strain analysis reveals closely linked QTLs with opposite effects on body weight.	GALNT3 SCN7A	5.22e-04	10	120	2	21451961
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	RRP1B CBX6 KMT2A SMARCD1 KIF2A SUZ12 KIF2C ATP5F1C	5.42e-04	533	120	8	30554943
Pubmed	EED and KDM6B coordinate the first mammalian cell lineage commitment to ensure embryo implantation.	NANOGP1 SUZ12	6.36e-04	11	120	2	23671187
Pubmed	Eml1 loss impairs apical progenitor spindle length and soma shape in the developing cerebral cortex.	KIF2A KIF2C	6.36e-04	11	120	2	29229923
Pubmed	Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference.	KIF2A KIF2C	6.36e-04	11	120	2	15843429
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	TTF2 RRP1B TUT7 IDH3B ESF1 TRMT6 UPF2 PDCD5 ABCD3 KIF2A TRAK2 DEPDC1B KIF2C ATP5F1C	6.63e-04	1496	120	14	32877691
Pubmed	Tsix RNA and the germline factor, PRDM14, link X reactivation and stem cell reprogramming.	NANOGP1 SUZ12	7.62e-04	12	120	2	24268575
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-6 ERVK-8	7.62e-04	12	120	2	14557543
Pubmed	Role for the MOV10 RNA helicase in polycomb-mediated repression of the INK4a tumor suppressor.	CBX6 SUZ12	7.62e-04	12	120	2	20543829
Pubmed	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	ANK2 UPF2 KIF13A	7.83e-04	52	120	3	22219177
Pubmed	Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins.	RRP1B PAXBP1 MCM3AP	7.83e-04	52	120	3	16780588
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	RRP1B ESF1 ASPM KMT2A KIF2A	8.31e-04	210	120	5	16565220
Pubmed	Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects.	GPC6 MYH14	8.98e-04	13	120	2	22993228
Pubmed	Combined Overexpression of JARID2, PRDM14, ESRRB, and SALL4A Dramatically Improves Efficiency and Kinetics of Reprogramming to Induced Pluripotent Stem Cells.	NANOGP1 SUZ12	8.98e-04	13	120	2	26523946
Pubmed	USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51-AKT signaling.	USP49 AGO1	8.98e-04	13	120	2	28363942
Pubmed	Maternal Ezh1/2 deficiency in oocyte delays H3K27me2/3 restoration and impairs epiblast development responsible for embryonic sub-lethality in mouse.	NANOGP1 SUZ12	8.98e-04	13	120	2	35796552
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	TTF2 SHROOM3 FRYL SMARCD1 KIF2A KIF2C ATP5F1C	9.34e-04	446	120	7	24255178
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	ANK2 NACA NBEA PSMD12 ABCD3 DEPDC1B ATP5F1C	9.71e-04	449	120	7	31732153
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	ESF1 ZNF518A KIF2A POLK KIF2C	1.06e-03	222	120	5	37071664
Pubmed	High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.	PRPF31 RRP1B TUT7 PSMD12 TRMT6 AGO1 KIF2A	1.25e-03	469	120	7	37314180
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	PRPF31 RRP1B ANKRD36C IDH3B PTK2 ESF1 AGO1 KMT2A ANKRD36 MAST3	1.25e-03	910	120	10	36736316
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	PRPF31 TTF2 NACA PSMD12 TRMT6 ASPM ABCD3	1.29e-03	472	120	7	38943005
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	CCDC137 NACA NBEA PSMD12 ABCD3 KMT2A RPL22L1 ARHGAP18 DEPDC1B ATP5F1C	1.31e-03	916	120	10	32203420
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	SETX CCDC137 RRP1B NACA SMARCD1 KIF2A RPL22L1 KIF2C	1.36e-03	615	120	8	31048545
Pubmed	Screening for replication of genome-wide SNP associations in sporadic ALS.	UPF2 ARHGAP18	1.37e-03	16	120	2	18987618
Pubmed	Joint effects of common genetic variants from multiple genes and pathways on the risk of premature coronary artery disease.	ABCA1 FCER1A	1.37e-03	16	120	2	20691829
Pubmed	Aurora B opposes PP1 function in mitosis by phosphorylating the conserved PP1-binding RVxF motif in PP1 regulatory proteins.	RRP1B ASPM	1.37e-03	16	120	2	29764992
Pubmed	Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers.	ANK2 PTPRZ1	1.37e-03	16	120	2	21745462
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	PRPF31 RRP1B TUT7 NACA ESF1 TRMT6 UPF2 ABCD3 KIF2A RPL22L1 KIF2C ATP5F1C	1.38e-03	1257	120	12	36526897
Pubmed	A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.	ARSJ ANK2 NEUROG2	1.43e-03	64	120	3	20332099
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	CCDC137 RRP1B PSMD12 MYH14 CBX6 PDCD5 ABCD3 ATP5F1C	1.49e-03	624	120	8	33729478
Pubmed	A human MAP kinase interactome.	SETX COBLL1 RAPGEF1 PTK2 MCM3AP CGNL1 TBC1D3F	1.53e-03	486	120	7	20936779
Cytoband	Ensembl 112 genes in cytogenetic band chr17q12	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F	2.48e-13	149	120	11	chr17q12
Cytoband	17q12	TBC1D3 TBC1D3H TBC1D3C TBC1D3B TBC1D3F	6.59e-06	99	120	5	17q12
GeneFamily	Glutamate metabotropic receptors\|Protein phosphatase 1 regulatory subunits	GRM6 GRM7	3.85e-04	8	68	2	281
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	RRP1B GRM7 PTK2 PPP1R3C KCNK10	5.96e-04	181	68	5	694
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF2A KIF13A KIF2C	6.88e-04	46	68	3	622
GeneFamily	ATP binding cassette subfamily A	ABCA1 ABCA10	1.23e-03	14	68	2	805
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	9.59e-10	90	110	9	PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05	ABCA1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	1.64e-07	213	110	10	PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	ABCA1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	1.64e-07	213	110	10	PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	DE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05	ABCA1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	5.31e-07	242	110	10	PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	ABCA1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	2.06e-06	281	110	10	PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05	ABCA1 TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F	2.06e-06	281	110	10	PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B CDRT4 TBC1D3G TBC1D3K TBC1D3F	6.51e-06	320	110	10	PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	USP49 SHROOM3 TBC1D3 TBC1D3H TBC1D3L TBC1D3D CA14 ANKRD36C TBC1D3C TBC1D3B USP21 CDRT4 KCNK10 ANKRD36 TBC1D3G TBC1D3K TBC1D3F	3.74e-05	1075	110	17	PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	USP49 SHROOM3 TBC1D3 TBC1D3H TBC1D3L ANK2 TBC1D3D ANKRD36C GPC6 TBC1D3C TBC1D3B USP21 CDRT4 CFAP126 KCNK10 ANKRD36 TBC1D3G TBC1D3K TBC1D3F	1.79e-04	1466	110	19	PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ATRN COBLL1 ICA1 GPRIN3 ABCA10 KCNJ1 UNC13C DEPDC1B	4.01e-08	195	114	8	a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 ICA1 ABCA10 PPP1R3C KCNJ1 DEPDC1B IGSF3	3.20e-07	173	114	7	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTF2 GALNT3 SCN7A ASPM RASL11B TRAK2 DEPDC1B	3.33e-07	174	114	7	9d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTF2 GALNT3 SCN7A ASPM RASL11B TRAK2 DEPDC1B	3.33e-07	174	114	7	53cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COBLL1 GPRIN3 GRM7 ADAM12 SCN7A CCDC68 UNC13C	4.86e-07	184	114	7	658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCell	10x5'v1-week_12-13-Lymphocytic_T-T_NK-NK_T_cell\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ARSJ GPRIN3 DENND2D ADAM12 PYHIN1 CDRT4 IL23R	5.22e-07	186	114	7	b099cb0902e9afb11218d70407d3cab212343c6d
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	SHROOM3 COBLL1 ICA1 GPRIN3 ABCA10 KCNJ1 DEPDC1B	5.61e-07	188	114	7	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 ICA1 ABCA10 KCNJ1 UNC13C DEPDC1B IGSF3	5.61e-07	188	114	7	eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHROOM3 GPRIN3 GPC6 PAXBP1 MYH14 CGNL1	1.07e-06	130	114	6	6434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 ABCA10 KCNJ1 SCN7A UNC13C DEPDC1B	1.65e-06	140	114	6	5e81fa3a19d23f0e9cae3878431ca1f78dff7238
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|368C / Donor, Lineage, Cell class and subclass (all cells)	ATRN ICA1 ADAM12 PYHIN1 ASPM IL23R	2.28e-06	148	114	6	80470353e12599440f711b6e107730763376d04d
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_4\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ICA1 ADAM12 ABCA10 FAM50B CFAP126 ANKRD36	2.66e-06	152	114	6	eb7ff36792c3c54ac88cfe976f84016b70b1a1d7
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NBEA ADAM12 PTPRZ1 SCN7A ARHGAP18 IGSF3	3.71e-06	161	114	6	3b5d7a3dab479c6959a428f3954dedd989900276
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ATRN ICA1 ADAM12 MCM3AP ASPM IL23R	5.60e-06	173	114	6	efb8072475000888efe088d00e870c56ffad4172
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ATRN ICA1 ADAM12 MCM3AP ASPM IL23R	5.79e-06	174	114	6	58300d64d3b6fd9ba1b6c87ea83b2777eb6be2f4
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GPRIN3 ADAM12 PYHIN1 KIF2A ANKRD36 IL23R	6.18e-06	176	114	6	003076f1a983409ddf31b9c19e61c1facdd72566
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TBC1D3L COBLL1 TBC1D24 KCNJ1 SCN7A DEPDC1B	6.39e-06	177	114	6	c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 ICA1 KCNJ1 SCN7A UNC13C DEPDC1B	7.49e-06	182	114	6	5f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 ABCA10 KCNJ1 SCN7A UNC13C DEPDC1B	7.73e-06	183	114	6	2f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCell	critical-Epithelial-Ionocyte\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ARSJ ANK2 GPC6 CSPG5 CCDC68 UNC13C	7.97e-06	184	114	6	58d36577eff814d46d72f031f3533d71549e3d6e
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHROOM3 ARSJ GPRIN3 GPC6 PAXBP1 MYH14	8.22e-06	185	114	6	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHROOM3 ARSJ GPC6 MYH14 ABCD3 CGNL1	8.48e-06	186	114	6	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHROOM3 GPRIN3 GPC6 PAXBP1 MYH14 CGNL1	8.48e-06	186	114	6	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 ABCA10 KCNJ1 SCN7A UNC13C DEPDC1B	8.74e-06	187	114	6	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 ICA1 ABCA10 KCNJ1 DEPDC1B IGSF3	9.01e-06	188	114	6	bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	COBLL1 HID1 ASPM UNC13C DEPDC1B KIF2C	9.01e-06	188	114	6	ecba5d06cbf3254448255a2aeefffe711f43310e
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	COBLL1 HID1 ASPM UNC13C DEPDC1B KIF2C	9.01e-06	188	114	6	8cf135da4d1d2500755d2809d60b41509af9fa8b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 ICA1 ABCA10 KCNJ1 CGNL1 DEPDC1B	9.29e-06	189	114	6	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 ICA1 ABCA10 KCNJ1 UNC13C DEPDC1B	9.29e-06	189	114	6	977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 ICA1 ABCA10 KCNJ1 SCN7A DEPDC1B	9.29e-06	189	114	6	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 ABCA10 KCNJ1 SCN7A UNC13C DEPDC1B	9.29e-06	189	114	6	e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 ICA1 ABCA10 KCNJ1 UNC13C DEPDC1B	9.57e-06	190	114	6	e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ICA1 TBC1D24 KCNJ1 SCN7A DEPDC1B IGSF3	1.11e-05	195	114	6	60d08fb27469d1e247bc47b651d7023ba82cf92f
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ICA1 GPC6 GRM6 TBC1D3C PYHIN1	1.18e-05	115	114	5	36cbb8666b33199b7552879922789bc227525b7b
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ICA1 GPC6 GRM6 TBC1D3C PYHIN1	1.18e-05	115	114	5	6f92e45cbe9924ade10cb8a41884b0202070ab31
ToppCell	COVID_non-vent-Lymphocytic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	GPRIN3 DENND2D ANKRD36C PYHIN1 KMT2A ANKRD36	1.18e-05	197	114	6	c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCell	mild-Treg\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ICA1 GPRIN3 ANKRD36C PYHIN1 KMT2A KIF2A	1.18e-05	197	114	6	39800e6e83f2d333b753d121c7aeb2912b91faa2
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	TUT7 ANKRD36C ESF1 UPF2 ASPM ANKRD36	1.18e-05	197	114	6	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MROH9 ICA1 GPC6 GRM7 PTPRZ1 UNC80	1.28e-05	200	114	6	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MROH9 ICA1 GPC6 GRM7 PTPRZ1 UNC80	1.28e-05	200	114	6	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MROH9 ICA1 GPC6 GRM7 PTPRZ1 UNC80	1.28e-05	200	114	6	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SETX COBLL1 PTK2 KIF2A ARHGAP18 KIF13A	1.28e-05	200	114	6	7034f57e282982c19c13ee8ab78eabaffa069e30
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MROH9 ICA1 GPC6 GRM7 PTPRZ1 UNC80	1.28e-05	200	114	6	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MROH9 ICA1 GPC6 GRM7 PTPRZ1 UNC80	1.28e-05	200	114	6	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MROH9 ICA1 GPC6 GRM7 PTPRZ1 UNC80	1.28e-05	200	114	6	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	LPS-antiTNF-Unknown-Endothelial-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CCDC150 ADAM12 ASPM DEPDC1B KIF2C	2.29e-05	132	114	5	02491930097b75aaeedab9e8200711b0dc610944
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADAM12 PTPRZ1 SCN7A CGNL1 IGSF3	3.47e-05	144	114	5	7de962346ba9653d90dd13bb7d977fe44d200bba
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 ICA1 TBC1D24 SCN7A DEPDC1B	5.09e-05	156	114	5	4d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_granulocytic-mast_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GPC6 FCER1A SCN7A CCDC68 ARHGAP18	5.57e-05	159	114	5	ecd1daa33549541aee3bf4e139ab6732efc8e74c
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_granulocytic\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GPC6 FCER1A SCN7A CCDC68 ARHGAP18	5.57e-05	159	114	5	7b6370c9567da7d40541c6e243efa704ed7e90ae
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_NKT-iNKT/MAIT-T-cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TTF2 CCDC137 DENND2D ASPM RASL11B	5.74e-05	160	114	5	5c931e859acf67c1c8664941e0e44d195f8ba75b
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAM12 KCNK10 ASPM DEPDC1B KIF2C	6.45e-05	164	114	5	4307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_2\|367C / Donor, Lineage, Cell class and subclass (all cells)	TTF2 ASPM SUZ12 DEPDC1B KIF2C	6.45e-05	164	114	5	0662cd9d21608efacc336e0a582859f3b9a4951d
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ADCY2 CSPG5 CCDC68 UNC13C TRAK2	6.45e-05	164	114	5	583dda853cee9491dbdcb228c23d8deadc20eb08
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAM12 KCNK10 ASPM DEPDC1B KIF2C	6.45e-05	164	114	5	1d84aa5b925f502ee9c5fa39714490f613a58028
ToppCell	NS-critical-d_16-33-Epithelial-Ionocyte\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ARSJ ANK2 CSPG5 UNC13C CGNL1	7.23e-05	168	114	5	6a233045638cb83dab64789b996b7598c325001e
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TTF2 CCDC150 ASPM DEPDC1B KIF2C	7.43e-05	169	114	5	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SHROOM3 COBLL1 GRM7 CCDC68 UNC13C	7.64e-05	170	114	5	3174ea9cf93892a8b41de10fd4ff6f06bb41502d
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTF2 SHROOM3 ADAM12 PRR12 MAST3	7.64e-05	170	114	5	b1a16600754e0c12f7d39c9221f1b03135833f16
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TTF2 ANK2 ASPM DEPDC1B KIF2C	7.86e-05	171	114	5	0eea035fde32cc2a75a0d4227911edb5d54ed47e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SHROOM3 ICA1 GPRIN3 ABCA10 DEPDC1B	8.30e-05	173	114	5	4bc6d93716f093b460c8b047199db8cab5fea720
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SHROOM3 COBLL1 GRM7 CCDC68 UNC13C	8.53e-05	174	114	5	ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SHROOM3 PTPRZ1 ASPM DEPDC1B KIF2C	8.76e-05	175	114	5	cc596907ea1a64ab7b5a8c7d4ad12e6ee59bfed9
ToppCell	10x_5'_v1-Neoplastic-Stem-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SHROOM3 PTPRZ1 ASPM DEPDC1B KIF2C	8.76e-05	175	114	5	a8400e7e47379901dcab5f2e364c3ff17765b4b9
ToppCell	Bronchial_Biopsy-Epithelial-Ionocytes\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ANK2 GPC6 CSPG5 CCDC68 UNC80	8.76e-05	175	114	5	13b8f7dc38c90b74d4a20a84a8705d8e2ec244f6
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GPRIN3 PYHIN1 KIF2A ANKRD36 IL23R	8.76e-05	175	114	5	cc2428150987911d0d382e8177918724aa69f85c
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Adult / Lineage, Cell type, age group and donor	ANK2 USH1C KCNK10 DEPDC1B UNC80	8.76e-05	175	114	5	4db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SHROOM3 PTPRZ1 ASPM DEPDC1B KIF2C	8.76e-05	175	114	5	8a3abf40146ae3459d97cdf865c1c8f6b92ac639
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231\|Adult / Lineage, Cell type, age group and donor	ANK2 USH1C KCNK10 DEPDC1B UNC80	8.76e-05	175	114	5	8d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SHROOM3 PTPRZ1 ASPM DEPDC1B KIF2C	8.76e-05	175	114	5	378d2b79edac91fc74eee0fb42bb29dd9b07c36f
ToppCell	10x3'2.3-week_14-16-Lymphocytic_T-T_NK-NK_T_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	GPRIN3 DENND2D TBC1D3B PYHIN1 IL23R	9.00e-05	176	114	5	f0c01fc4f9c17c4d724642d9931731eef2b10258
ToppCell	10x3'2.3-week_12-13-Lymphocytic_T-T_NK-NK_T_cell\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	GPRIN3 DENND2D GRM6 PYHIN1 IL23R	9.24e-05	177	114	5	e1ba7e17af2c54d3c78cdf85882168c5b896e453
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COBLL1 GRM7 PTPRZ1 CCDC68 UNC13C	9.24e-05	177	114	5	f902600c639087664316b3cf30cab243bc3d1c5c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPC6 GRM7 ADAM12 ADCY2 ABCA10	9.24e-05	177	114	5	9ec7f1e64312d26d434b3312b58386715dbad644
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 ICA1 KCNJ1 DEPDC1B IGSF3	9.24e-05	177	114	5	dc846d0feb94d4c289553cc3ac9dac81d10409cb
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPC6 GRM7 ADAM12 ADCY2 ABCA10	9.24e-05	177	114	5	016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCell	Healthy-Plasmablast\|Healthy / disease group, cell group and cell class	COBLL1 HID1 ASPM UNC13C DEPDC1B	9.24e-05	177	114	5	4ff75c609ac9edf7a94bda42eb7124c559e8b6aa
ToppCell	Control-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	MROH9 GALNT3 COBLL1 RFTN1 KCNK10	9.24e-05	177	114	5	e82115bfc32c7b689460fbc5caeb983c1aabe30f
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHROOM3 GPRIN3 GPC6 MYH14 CGNL1	9.24e-05	177	114	5	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	Control-Epithelial_alveolar-AT_1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHROOM3 GPRIN3 GPC6 MYH14 CGNL1	9.49e-05	178	114	5	aa7d43c655df493f1330a5001efaa484e4a19f69
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COBLL1 GRM7 PTPRZ1 CCDC68 UNC13C	9.75e-05	179	114	5	8766a5a066091879f521acfc612abf563ff78808
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHROOM3 ARSJ COBLL1 GPC6 MYH14	9.75e-05	179	114	5	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	NS-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ARSJ ANK2 CSPG5 UNC13C CGNL1	9.75e-05	179	114	5	65a96bee7bc28f5bfc20f0fd92bcc0ab2eb5e06c
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TTF2 CCDC150 ASPM DEPDC1B KIF2C	1.00e-04	180	114	5	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GPRIN3 PYHIN1 RFTN1 PAXBP1 KMT2A	1.03e-04	181	114	5	986c036e656f24fe374807e2711cec9e3c83c892
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARSJ CCDC68 RASL11B UNC13C UNC80	1.03e-04	181	114	5	d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHROOM3 GPC6 PAXBP1 MYH14 CGNL1	1.03e-04	181	114	5	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SHROOM3 ICA1 GPRIN3 ABCA10 DEPDC1B	1.03e-04	181	114	5	e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPC6 GRM7 CCDC68 UNC13C MAST3	1.05e-04	182	114	5	14a117c5e50db31ee1b2cf4df4d133451fd6d55f
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHROOM3 ARSJ GPC6 MYH14 ABCD3	1.05e-04	182	114	5	17ed11a7ea366dd3106400511d5e628d3f1a9c3e
ToppCell	NS-critical-d_07-13-Epithelial-Ionocyte\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ARSJ ANK2 GPC6 CSPG5 UNC13C	1.08e-04	183	114	5	ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GALNT3 USH1C ADGRG7 MYH14 DEPDC1B	1.08e-04	183	114	5	0d21befacefc6c597e7b501ed41b7fe9385a78df
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 ICA1 KCNJ1 UNC13C DEPDC1B	1.08e-04	183	114	5	2e831a4d99c6f983793df71c0994124c943c6da9
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHROOM3 GPC6 PAXBP1 MYH14 CGNL1	1.11e-04	184	114	5	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHROOM3 ARSJ GPC6 MYH14 ABCD3	1.11e-04	184	114	5	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4\|TCGA-Thryoid / Sample_Type by Project: Shred V9	MYH14 ARHGAP18 POU2F3 DEPDC1B IGSF3	1.11e-04	184	114	5	d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GALNT3 COBLL1 ICA1 MYH14 PTPRZ1	1.11e-04	184	114	5	fa4915b0498f3069fd5ef497286445528f75187e
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ICA1 NBEA HID1 ANKRD36C ANKRD36	1.11e-04	184	114	5	01c19a830348ab0b9c02c1546a439de70ee10f97
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CA14 PTPRZ1 ASPM DEPDC1B KIF2C	1.14e-04	185	114	5	282b3de8850f3c21704339e8d8737b432a43441a
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-AT2_Progenitor\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHROOM3 ARSJ GPC6 MYH14 PDCD5	1.14e-04	185	114	5	929b68b05b7686341329ac756d7df172cb4b810b
Disease	Global developmental delay	NBEA PRR12 AGO1 PACS2 SMARCD1 SUZ12	5.95e-06	133	99	6	C0557874
Disease	Schizophrenia	ABCA1 CCDC137 GRM7 ADAM12 PTPRZ1 CSPG5 ERVK-8 CCDC68 KMT2A KIF2A CGNL1 ARHGAP18	4.07e-05	883	99	12	C0036341
Disease	Weaver syndrome	KMT2A SUZ12	1.11e-04	5	99	2	C0265210
Disease	visual epilepsy (is_implicated_in)	TBC1D24 ASPM	6.01e-04	11	99	2	DOID:11832 (is_implicated_in)
Disease	cholesterol to total lipids in large LDL percentage	ABCA1 COBLL1 POLK	8.93e-04	56	99	3	EFO_0022235
Disease	low density lipoprotein particle size measurement	ABCA1 COBLL1 POLK	9.89e-04	58	99	3	EFO_0008593
Disease	language measurement	HID1 GRM7 RFTN1 CGNL1	1.10e-03	134	99	4	EFO_0007797
Disease	Generalized hypotonia	AGO1 SMARCD1	1.14e-03	15	99	2	C1858120
Disease	sleep duration	USP49 ICA1 GRM6 PRR12 KMT2A ARHGAP18	1.41e-03	362	99	6	EFO_0005271
Disease	intraocular pressure measurement	MROH9 TTF2 ABCA1 ICA1 ADAM12 CCDC68 KMT2A	1.66e-03	509	99	7	EFO_0004695
Disease	familial hyperlipidemia (biomarker_via_orthology)	ABCA1 SMARCD1	1.84e-03	19	99	2	DOID:1168 (biomarker_via_orthology)
Disease	CCL4 measurement	TBC1D3 TBC1D3F	2.04e-03	20	99	2	EFO_0004751
Disease	corneal hysteresis	ABCA10 CCDC68	2.04e-03	20	99	2	EFO_0010066
Disease	Glioblastoma	PTK2 SUZ12 POLK	2.41e-03	79	99	3	C0017636
Disease	Nonsyndromic Deafness	USH1C TBC1D24 MYH14	2.59e-03	81	99	3	C3711374
Disease	Giant Cell Glioblastoma	PTK2 SUZ12 POLK	2.87e-03	84	99	3	C0334588
Disease	HDL cholesterol change measurement	ABCA1 ABCA10	2.93e-03	24	99	2	EFO_0007805

Protein segments in the cluster

Peptide	Gene	Start	Entry
INLIRTKKTVSIKVR	USH1C	151	Q9Y6N9
ISNKKRKKAAQVTFR	CCDC137	81	Q6PK04
TQQQVTFLLKIKRTR	FCER1A	226	P12319
QKRSKQTVEFLLTKN	ANKRD30B	181	Q9BXX2
KTENTKLRRTNKFRT	CSPG5	451	O95196
KSKKFSESVLRTQIR	CBX6	211	O95503
SCFSTRKKKIAIRNV	ABCA10	1211	Q8WWZ4
RKVLRTLQQIKKSSS	ABCA1	126	O95477
SQRVRFTKEIKGLKV	AGO1	251	Q9UL18
RTVAQIKATVKRKVY	BAP18	71	Q8IXM2
RKTLIRLLFTNKKTT	ADAM12	731	O43184
EVTRKQTVQLLKKFL	DEPDC1B	66	Q8WUY9
IFKKKVSLLNIATRI	ANKRD36	1236	A6QL64
LTVIFQIVTRKVRKT	ADGRG7	451	Q96K78
YVKKIRTTLQKIRTQ	CCDC68	36	Q9H2F9
TVRVVINFKKTQKTI	COBLL1	146	Q53SF7
RVRFLNLKKTIIKFQ	ASPM	1576	Q8IZT6
RFISLKKATIFVQRK	ASPM	2426	Q8IZT6
VRVKTERKNFLAVQK	ASPM	2726	Q8IZT6
FRAILIKKTDRSQKT	RFTN1	101	Q14699
VKKVTRKIIRRYVSS	ANK2	3896	Q01484
TSQTVKRLIEKSKTR	CDRT4	36	Q8N9R6
FKKKVSLLNIATRIT	ANKRD36C	1101	Q5JPF3
TKKFRLITVRKIATI	SLC17A3	281	O00476
KTAETVQRIKKTRRL	NEUROG2	101	Q9H2A3
VKKLLRRLSQFNKTA	ARSJ	516	Q5FYB0
LTTQKKVEFVLKQLR	ATRN	826	O75882
KVQRIFTRRSKKLAV	MCM3AP	461	O60318
LIKSIKTKTEQFQAR	ESF1	831	Q9H501
QRQLVSTLEKKQRKF	MYH14	1456	Q7Z406
QQTEKTTTVKFNRRK	PDCD5	101	O14737
IKTKQIQRSIIRLFS	OR51B4	291	Q9Y5P0
IAKAVLRTKSKASQR	OR2W1	221	Q9Y3N9
IRQRIIKKFQFIKSL	OR51G1	301	Q8NGK1
NTLRVKKIFLNKTLT	FRYL	481	O94915
ERTNRTLKTQLVKQK	HERVK_113	746	P63132
RVEKVFRKKQVSQTK	KCNK10	216	P57789
FRKKQVSQTKIRVIS	KCNK10	221	P57789
RTQIISKKINTKFFQ	PSMD12	201	O00232
TVRNFTLRNTKIKKG	PTPRZ1	1866	P23471
VKTKQIRKRVVRVFQ	OR52P1	296	Q8NH57
RRIVFSVKEKSQRQK	PAXBP1	271	Q9Y5B6
FKQKVVALLRRFKVS	PACS2	251	Q86VP3
INKVLRFTVTKVRKY	MROH9	146	Q5TGP6
KRKKRTSIETNIRLT	POU2F3	281	Q9UKI9
ERTNRTLKTQLVKQK	ERVK-7	746	P63135
ERTNRTLKTQLVKQK	ERVK-6	746	Q9BXR3
FKKQRKAQNFTSILI	NPY6R	61	Q99463
ERTNRTLKTQLVKQK	ERVK-18	746	Q9QC07
AKVNKIVKNRRTVAS	KIF2A	86	O00139
QNRTLRTKSQKKRFE	ADCY2	536	Q08462
LKIVTRAKSQRIAKF	IDH3B	186	O43837
QVSKSKRTLTLVENK	IGSF3	681	O75054
KLKIQVTRAFIAART	GPC6	206	Q9Y625
VQKRKRSLKATSTVA	GRM6	851	O15303
LRKQFQTERETTKKV	CCDC150	831	Q8NCX0
RKVNLVFEKIQTLKS	CGNL1	576	Q0VF96
KQFSIVKIVRQRERK	GALNT3	241	Q14435
IKERFQITRINKTTA	IL23R	71	Q5VWK5
RKFIKKRIIIISNYS	PYHIN1	261	Q6K0P9
LRKKSITKTVQQARS	CFAP126	126	Q5VTH2
RRKSLFKKISKQTSV	MAST3	1071	O60307
VQKRKRSFKAVVTAA	GRM7	856	Q14831
GRKVKTQVKNIRQFI	KMT2A	396	Q03164
ITRRLKSIKNIQKIT	ATP5F1C	31	P36542
SKLQLKQSKRVRDVV	GPRIN3	671	Q6ZVF9
RKKRLENRKSVVFTS	CA14	316	Q9ULX7
VTIQKQKRRSVNSKI	KIF2C	86	Q99661
KTNRRFVKKFVKTQL	DENND2D	416	Q9H6A0
NTKANRKKLVRALFI	UPF2	596	Q9HAU5
FRKVQTQVRLAKKNF	ICA1	191	Q05084
KQSFTQSLKRRISLK	KIF13A	1281	Q9H1H9
KRRFKQALSAKVRTV	RASL11B	231	Q9BPW5
QKLARVTQVRKELKS	RPRD1B	281	Q9NQG5
RAVKKLRQYISVKTQ	RRP1B	26	Q14684
KNVSFEKKVQIRITF	PPP1R3C	176	Q9UQK1
IKQKRKLRIFISNTF	SMARCD1	176	Q96GM5
KAKTLRKLIQQTFRQ	PTK2	216	Q05397
DVVKSKKTFRSQAIV	NBEA	2106	Q8NFP9
SKLNFRKAVIQLTTK	HID1	6	Q8IV36
RIQRATTVSQKKSSK	SETX	1211	Q7Z333
KENSVKRKAIQRTVS	SHROOM3	1711	Q8TF72
SKLKRSVVRAQEFKV	PRR12	1946	Q9ULL5
TRIAFKVQQKRLTKT	TBC1D3L	301	B9A6J9
KRKEVIFSKQLNTTI	MSANTD4	26	Q8NCY6
KREKQTVHSVFRKLV	ABCD3	286	P28288
ITVKQKSVSLSKRQF	TBC1D24	316	Q9ULP9
TRIAFKVQQKRLTKT	TBC1D3B	301	A6NDS4
TRIAFKVQQKRLTKT	TBC1D3H	301	P0C7X1
KQKAQQKRVFDTVRI	TRAK2	396	O60296
RQKTRSTKKLTVQRF	USP21	441	Q9UK80
IRQSSKVKFTSAVKL	UNC80	1116	Q8N2C7
KNKITVVSEKQFSKR	RPL22L1	61	Q6P5R6
TVQVGKNKRRTKTIF	UNC13C	1246	Q8NB66
KKRVSKNTFFVLVRV	RAPGEF1	751	Q13905
LQVSKKRLISVKNYR	THAP9	146	Q9H5L6
TRIAFKVQQKRLTKT	TBC1D3F	301	A6NER0
FTRRRSQIKTDVKKA	RNF148	221	Q8N7C7
RNSRTNIKRKTFKVD	SUZ12	121	Q15022
ERTNRTLKTQLVKQK	ERVK-10	746	P10266
VTIKLKNVNFEVKTR	POLK	456	Q9UBT6
ERTNRTLKTQLVKQK	ERVK-8	746	P63133
TKARISKTLQRTLQK	PRPF31	416	Q8WWY3
RKLTKQVLKVVNTIF	USP49	431	Q70CQ1
ERTNRTLKTQLVKQK	ERVK-11	746	Q9UQG0
TRIAFKVQQKRLTKT	TBC1D3E	301	A0A087X179
RKLFQSKQQTARKSI	ZNF518A	71	Q6AHZ1
TIQTFVKKAKSSKRR	PHF23	86	Q9BUL5
KKSQKVTLFSRIKRI	TXNDC8	81	Q6A555
RVETVSQTLRKKNKQ	ARHGAP18	151	Q8N392
VKKQKTRTVFSSTQL	NANOGP1	36	Q8N7R0
AVQVQRRKKVTFEKQ	TRMT6	36	Q9UJA5
KKNTFIVLNKNRTIF	SCN7A	76	Q01118
TRIAFKVQQKRLTKT	TBC1D3D	301	A0A087WVF3
ISIRRKSLLTTFKKQ	TUT7	1256	Q5VYS8
TRIAFKVQQKRLTKT	TBC1D3G	301	Q6DHY5
TRIAFKVQQKRLTKT	TBC1D3	301	Q8IZP1
TRIAFKVQQKRLTKT	TBC1D3K	301	A0A087X1G2
TRIAFKVQQKRLTKT	TBC1D3I	301	A0A087WXS9
TRIAFKVQQKRLTKT	TBC1D3C	301	Q6IPX1
VARRVYLTTQLKQKK	TTF2	411	Q9UNY4
VRVRKGNTVQQFLKK	FAM50B	201	Q9Y247
KKRAKTITFSKNAVI	KCNJ1	186	P48048
RVTIRKSKNILFVIT	NACA	1956	E9PAV3
VTRVTIRKSKNILFV	NACA	91	Q13765
TRVTIRKSKNILFVI	NACA4P	91	Q9BZK3