Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	microfilament motor activity	MYO1C MYO7B MYH14 ACTC1	2.32e-05	38	88	4	GO:0000146
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYO1C MYO7B MYH14 STARD9 ACTC1	1.75e-04	118	88	5	GO:0003774
GeneOntologyMolecularFunction	cytoskeletal protein binding	NF1 NEK6 MYO1C TRPM7 MYO7B MYH14 STARD9 ACTA1 ACTC1 AGBL1 UTRN PPP1R42 PTPRT TTLL7	3.05e-04	1099	88	14	GO:0008092
GeneOntologyBiologicalProcess	mesenchyme migration	ACTA1 ACTA2 ACTC1	7.46e-07	5	88	3	GO:0090131
Domain	ACTINS_1	ACTA1 ACTA2 ACTC1	5.19e-06	8	86	3	PS00406
Domain	Actin_CS	ACTA1 ACTA2 ACTC1	5.05e-05	16	86	3	IPR004001
Domain	ACTINS_2	ACTA1 ACTA2 ACTC1	6.12e-05	17	86	3	PS00432
Domain	Actin/actin-like_CS	ACTA1 ACTA2 ACTC1	7.32e-05	18	86	3	IPR020902
Domain	ACTINS_ACT_LIKE	ACTA1 ACTA2 ACTC1	8.66e-05	19	86	3	PS01132
Domain	Actin	ACTA1 ACTA2 ACTC1	3.86e-04	31	86	3	IPR004000
Domain	Actin	ACTA1 ACTA2 ACTC1	3.86e-04	31	86	3	PF00022
Domain	ACTIN	ACTA1 ACTA2 ACTC1	3.86e-04	31	86	3	SM00268
Domain	Myosin_head_motor_dom	MYO1C MYO7B MYH14	7.08e-04	38	86	3	IPR001609
Domain	MYOSIN_MOTOR	MYO1C MYO7B MYH14	7.08e-04	38	86	3	PS51456
Domain	Myosin_head	MYO1C MYO7B MYH14	7.08e-04	38	86	3	PF00063
Domain	MYSc	MYO1C MYO7B MYH14	7.08e-04	38	86	3	SM00242
Domain	Rho_GTPase_activation_prot	NF1 ARHGAP20 CHN2 SYNGAP1	7.28e-04	88	86	4	IPR008936
Pubmed	Reexamination of chromosomal loci of human muscle actin genes by fluorescence in situ hybridization.	ACTA1 ACTA2 ACTC1	1.62e-08	3	89	3	7780165
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CASC3 PTPN13 AMER1 NEK6 ZNF608 MYCBP2 MYH14 GLI2 ENPP5 PARD3B SLITRK3 MEIS3 RERE H6PD ZNF236 UTRN SESN1 SGK2	3.55e-08	1489	89	18	28611215
Pubmed	HIV-1 Tat protein inhibits neurosecretion by binding to phosphatidylinositol 4,5-bisphosphate.	PIKFYVE ACTA1 ACTA2	1.61e-07	5	89	3	23178941
Pubmed	Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient mouse model of biliary atresia.	GLI2 ACTA2 SOX17 PKHD1	2.83e-07	22	89	4	28432216
Pubmed	Virus assembly and plasma membrane domains: which came first?	ACTA1 ACTA2 ACTC1	3.22e-07	6	89	3	22989508
Pubmed	HIV-1 protease cleaves actin during acute infection of human T-lymphocytes.	ACTA1 ACTA2 ACTC1	3.22e-07	6	89	3	1540415
Pubmed	HIV type 1 Gag and nucleocapsid proteins: cytoskeletal localization and effects on cell motility.	ACTA1 ACTA2 ACTC1	3.22e-07	6	89	3	11709093
Pubmed	Actin associates with the nucleocapsid domain of the human immunodeficiency virus Gag polyprotein.	ACTA1 ACTA2 ACTC1	3.22e-07	6	89	3	9971772
Pubmed	Tagging the human immunodeficiency virus gag protein with green fluorescent protein. Minimal evidence for colocalisation with actin.	ACTA1 ACTA2 ACTC1	3.22e-07	6	89	3	10049817
Pubmed	Human immunodeficiency virus nucleocapsid protein polymorphisms modulate the infectivity of RNA packaging mutants.	ACTA1 ACTA2 ACTC1	3.22e-07	6	89	3	12009869
Pubmed	HIV-1 Tat protein variants: critical role for the cysteine region in synaptodendritic injury.	ACTA1 ACTA2 ACTC1	3.22e-07	6	89	3	23811015
Pubmed	Retroviral assembly and budding occur through an actin-driven mechanism.	ACTA1 ACTA2 ACTC1	3.22e-07	6	89	3	19883584
Pubmed	Dynamic imaging of cell-free and cell-associated viral capture in mature dendritic cells.	ACTA1 ACTA2 ACTC1	3.22e-07	6	89	3	21917091
Pubmed	HIV-1 Gag protein associates with F-actin present in microfilaments.	ACTA1 ACTA2 ACTC1	3.22e-07	6	89	3	8661406
Pubmed	A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.	ACTA1 ACTA2 ACTC1	3.22e-07	6	89	3	23017337
Pubmed	Interaction of the human immunodeficiency virus type 1 nucleocapsid with actin.	ACTA1 ACTA2 ACTC1	3.22e-07	6	89	3	10074138
Pubmed	Synaptodendritic recovery following HIV Tat exposure: neurorestoration by phytoestrogens.	ACTA1 ACTA2 ACTC1	3.22e-07	6	89	3	23875777
Pubmed	Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton.	ACTA1 ACTA2 ACTC1	3.22e-07	6	89	3	9841925
Pubmed	HIV-1 replication from after cell entry to the nuclear periphery.	ACTA1 ACTA2 ACTC1	5.63e-07	7	89	3	17504171
Pubmed	The PDZ-adaptor protein syntenin-1 regulates HIV-1 entry.	ACTA1 ACTA2 ACTC1	5.63e-07	7	89	3	22535526
Pubmed	siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.	ACTA1 ACTA2 ACTC1	5.63e-07	7	89	3	22465675
Pubmed	Mice lacking factor VII develop normally but suffer fatal perinatal bleeding.	ACTA1 ACTA2 ACTC1	5.63e-07	7	89	3	9384381
Pubmed	A Novel Mouse Model for Cilia-Associated Cardiovascular Anomalies with a High Penetrance of Total Anomalous Pulmonary Venous Return.	ACTA1 ACTA2 ACTC1	5.63e-07	7	89	3	30289203
Pubmed	Selective targeting of ITK blocks multiple steps of HIV replication.	ACTA1 ACTA2 ACTC1	5.63e-07	7	89	3	18443296
Pubmed	The trinity of the cortical actin in the initiation of HIV-1 infection.	ACTA1 ACTA2 ACTC1	5.63e-07	7	89	3	22640593
Pubmed	Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.	ACTA1 ACTA2 ACTC1	8.99e-07	8	89	3	14694110
Pubmed	Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling.	ACTA1 ACTA2 ACTC1	8.99e-07	8	89	3	20147394
Pubmed	Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I.	TNNI3K ACTA1 ACTC1	8.99e-07	8	89	3	12721663
Pubmed	Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.	ACTA1 ACTA2 ACTC1	8.99e-07	8	89	3	23260110
Pubmed	Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies.	ACTA1 ACTA2 ACTC1	8.99e-07	8	89	3	20096780
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	EPPK1 NF1 MYO1C COPA MYCBP2 MYH14 PYGB UTP20 PFAS URB2 UTRN	9.12e-07	653	89	11	22586326
Pubmed	Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.	ACTA1 ACTA2 ACTC1	1.35e-06	9	89	3	12297046
Pubmed	Cytoskeletal proteins inside human immunodeficiency virus type 1 virions.	ACTA1 ACTA2 ACTC1	1.35e-06	9	89	3	8892894
Pubmed	Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF.	ACTA1 ACTA2 ACTC1	1.35e-06	9	89	3	10556093
Pubmed	HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells.	ACTA1 ACTA2 ACTC1	1.35e-06	9	89	3	18775311
Pubmed	Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease.	ACTA1 ACTA2 ACTC1	1.92e-06	10	89	3	21749862
Pubmed	Non-viral cellular substrates for human immunodeficiency virus type 1 protease.	ACTA1 ACTA2 ACTC1	1.92e-06	10	89	3	1991513
Pubmed	Gelsolin activity controls efficient early HIV-1 infection.	ACTA1 ACTA2 ACTC1	1.92e-06	10	89	3	23575248
Pubmed	Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus.	ACTA1 ACTA2 ACTC1	1.92e-06	10	89	3	1907279
Pubmed	CAP2 deficiency delays myofibril actin cytoskeleton differentiation and disturbs skeletal muscle architecture and function.	ACTA1 ACTA2 ACTC1	2.63e-06	11	89	3	30962377
Pubmed	N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.	ACTA1 ACTA2 ACTC1	2.63e-06	11	89	3	23294842
Pubmed	Quantitative proteomic analysis of lentiviral vectors using 2-DE.	ACTA1 ACTA2 ACTC1	2.63e-06	11	89	3	19639585
Pubmed	FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity.	ACTA1 ACTA2 ACTC1	2.63e-06	11	89	3	22207710
Pubmed	HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination.	ACTA1 ACTA2 ACTC1	3.50e-06	12	89	3	23071112
Pubmed	SEMA6D regulates perinatal cardiomyocyte proliferation and maturation in mice.	ACTA1 ACTA2 ACTC1	3.50e-06	12	89	3	31042497
Pubmed	Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice.	ACTA1 ACTA2 ACTC1	4.55e-06	13	89	3	18400219
Pubmed	LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes.	ACTA1 ACTA2 ACTC1	5.78e-06	14	89	3	21923909
Pubmed	Regulating the functions of the HIV-1 matrix protein.	ACTA1 ACTA2 ACTC1	5.78e-06	14	89	3	17411366
Pubmed	Rescue of skeletal muscle alpha-actin-null mice by cardiac (fetal) alpha-actin.	ACTA1 ACTC1	6.48e-06	2	89	2	19468071
Pubmed	Investigation of changes in skeletal muscle alpha-actin expression in normal and pathological human and mouse hearts.	ACTA1 ACTC1	6.48e-06	2	89	2	20706863
Pubmed	alpha-Actin proteins and gene transcripts are colocalized in embryonic mouse muscle.	ACTA1 ACTC1	6.48e-06	2	89	2	1893870
Pubmed	A 5' duplication of the alpha-cardiac actin gene in BALB/c mice is associated with abnormal levels of alpha-cardiac and alpha-skeletal actin mRNAs in adult cardiac tissue.	ACTA1 ACTC1	6.48e-06	2	89	2	3023046
Pubmed	Muscle specific expression of Cre recombinase under two actin promoters in transgenic mice.	ACTA2 ACTC1	6.48e-06	2	89	2	10686609
Pubmed	Transcripts of alpha-cardiac and alpha-skeletal actins are early markers for myogenesis in the mouse embryo.	ACTA1 ACTC1	6.48e-06	2	89	2	3075543
Pubmed	Large-scale opening of utrophin's tandem calponin homology (CH) domains upon actin binding by an induced-fit mechanism.	ACTA1 UTRN	6.48e-06	2	89	2	21768337
Pubmed	A developmental study of the abnormal expression of alpha-cardiac and alpha-skeletal actins in the striated muscle of a mutant mouse.	ACTA1 ACTC1	6.48e-06	2	89	2	2731651
Pubmed	SPRED2 loss-of-function causes a recessive Noonan syndrome-like phenotype.	NF1 SPRED2	6.48e-06	2	89	2	34626534
Pubmed	A fetal skeletal muscle actin mRNA in the mouse and its identity with cardiac actin mRNA.	ACTA1 ACTC1	6.48e-06	2	89	2	6897014
Pubmed	Severe protein aggregate myopathy in a knockout mouse model points to an essential role of cofilin2 in sarcomeric actin exchange and muscle maintenance.	ACTA1 ACTA2 ACTC1	7.21e-06	15	89	3	24598388
Pubmed	Extraocular muscle morphogenesis and gene expression are regulated by Pitx2 gene dose.	ACTA1 ACTA2 ACTC1	8.86e-06	16	89	3	16638982
Pubmed	Serum response factor is essential for mesoderm formation during mouse embryogenesis.	ACTA1 ACTA2 ACTC1	8.86e-06	16	89	3	9799237
Pubmed	Requirement for an intact T-cell actin and tubulin cytoskeleton for efficient assembly and spread of human immunodeficiency virus type 1.	ACTA1 ACTA2 ACTC1	1.07e-05	17	89	3	17360745
Pubmed	The cleavage of host cell proteins by HIV-1 protease.	ACTA1 ACTA2 ACTC1	1.07e-05	17	89	3	8997639
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CASC3 PTPN13 AMER1 NF1 MYCBP2 TRPM7 CLK3 STARD9 PARD3B DPP8 UTRN	1.27e-05	861	89	11	36931259
Pubmed	A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice.	ACTA1 ACTA2 ACTC1	1.29e-05	18	89	3	24840128
Pubmed	Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets.	ACTA1 ACTA2 ACTC1	1.29e-05	18	89	3	15929941
Pubmed	Myocardial-specific ablation of Jumonji and AT-rich interaction domain-containing 2 (Jarid2) leads to dilated cardiomyopathy in mice.	ACTA1 ACTA2 ACTC1	1.52e-05	19	89	3	30700554
Pubmed	Deciphering gene expression program of MAP3K1 in mouse eyelid morphogenesis.	GLI2 ACTA1 ACTA2	1.52e-05	19	89	3	23201579
Pubmed	Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis.	ACTA1 ACTA2 ACTC1	1.52e-05	19	89	3	18316483
Pubmed	Cerebral Vein Malformations Result from Loss of Twist1 Expression and BMP Signaling from Skull Progenitor Cells and Dura.	ACTA2 SOX17 ACVR2A	1.79e-05	20	89	3	28844842
Pubmed	Bmp2 regulates the interaction between EPDCs and myocytes in cardiac OFT.	ACTA1 ACTC1	1.94e-05	3	89	2	22647617
Pubmed	Lineage tree for the venous pole of the heart: clonal analysis clarifies controversial genealogy based on genetic tracing.	ACTA1 ACTC1	1.94e-05	3	89	2	22855565
Pubmed	Actin and myosin genes are transcriptionally regulated during mouse skeletal muscle development.	ACTA1 ACTC1	1.94e-05	3	89	2	1728592
Pubmed	Crystal structure of the complex between actin and human vitamin D-binding protein at 2.5 A resolution.	ACTA1 ACTA2	1.94e-05	3	89	2	12119014
Pubmed	Down-regulation of a novel actin-binding molecule, skeletrophin, in malignant melanoma.	ACTA1 ACTC1	1.94e-05	3	89	2	14507647
Pubmed	Actin-DBP: the perfect structural fit?	ACTA1 ACTC1	1.94e-05	3	89	2	12554937
Pubmed	Utrophin binds laterally along actin filaments and can couple costameric actin with sarcolemma when overexpressed in dystrophin-deficient muscle.	ACTA1 UTRN	1.94e-05	3	89	2	12006649
Pubmed	The human beta-actin multigene family.	ACTA1 ACTA2	1.94e-05	3	89	2	3842206
Pubmed	Morphology of the developing muscularis externa in the mouse esophagus.	ACTA1 ACTA2	1.94e-05	3	89	2	21595780
Pubmed	The role of different Scinderin domains in the control of F-actin cytoskeleton during exocytosis.	ACTA1 ACTC1	1.94e-05	3	89	2	12438125
Pubmed	Comparison of three actin-coding sequences in the mouse; evolutionary relationships between the actin genes of warm-blooded vertebrates.	ACTA1 ACTC1	1.94e-05	3	89	2	3084797
Pubmed	The genes coding for the cardiac muscle actin, the skeletal muscle actin and the cytoplasmic beta-actin are located on three different mouse chromosomes.	ACTA1 ACTC1	1.94e-05	3	89	2	6641707
Pubmed	Retinoic acid regulates differentiation of the secondary heart field and TGFbeta-mediated outflow tract septation.	ACTA1 ACTA2 ACTC1	2.08e-05	21	89	3	20230754
Pubmed	Myocardial Mycn is essential for mouse ventricular wall morphogenesis.	ACTA1 ACTA2 ACTC1	2.08e-05	21	89	3	23063798
Pubmed	Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.	ERCC2 NF1 SPRED2 LARS1 UTP20 PFAS URB2 UROD	2.22e-05	454	89	8	33226137
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	METAP1 PTPN13 SPRED2 COPA MYCBP2 TRPM7 MYH14 LARS1 ENPP5 UROD UTRN RNF111 SYNGAP1	2.33e-05	1285	89	13	35914814
Pubmed	Modifications in the human T cell proteome induced by intracellular HIV-1 Tat protein expression.	ACTA1 ACTA2 ACTC1	2.41e-05	22	89	3	16526095
Pubmed	Stromal netrin 1 coordinates renal arteriogenesis and mural cell differentiation.	ACTA2 SOX17 MEIS3	2.41e-05	22	89	3	37823339
Pubmed	Essential and supporting host cell factors for HIV-1 budding.	ACTA1 ACTA2 ACTC1	2.76e-05	23	89	3	22004035
Pubmed	Polymerisation of chemically cross-linked actin:thymosin beta(4) complex to filamentous actin: alteration in helical parameters and visualisation of thymosin beta(4) binding on F-actin.	ACTA1 ACTA2	3.87e-05	4	89	2	11812134
Pubmed	Phosphorylation of spinophilin modulates its interaction with actin filaments.	ACTA1 ACTC1	3.87e-05	4	89	2	12417592
Pubmed	Transcriptional regulation of actin and myosin genes during differentiation of a mouse muscle cell line.	ACTA1 ACTC1	3.87e-05	4	89	2	2201580
Pubmed	Transport and localization of the DEG/ENaC ion channel BNaC1alpha to peripheral mechanosensory terminals of dorsal root ganglia neurons.	NF1 MYO1C	3.87e-05	4	89	2	11306621
Pubmed	A severe form of Noonan syndrome and autosomal dominant café-au-lait spots - evidence for different genetic origins.	NF1 SPRED2	3.87e-05	4	89	2	19120036
Pubmed	Interaction between protein kinase C and actin in megakaryocyte polyploidization.	ACTA1 ACTA2	3.87e-05	4	89	2	10628374
Pubmed	Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.	ACTA1 ACTA2 ACTC1	4.04e-05	26	89	3	24742657
Pubmed	Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome.	ACTA1 ACTA2 UTRN	4.53e-05	27	89	3	18468998
Pubmed	Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase.	COPA MYCBP2 LARS1 SYNGAP1	5.20e-05	79	89	4	29121065
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	EPPK1 NF1 COPA MYCBP2 MYH14 ACTA1 LARS1 ACTC1 UTP20 URB2 UTRN	6.14e-05	1024	89	11	24711643
Pubmed	Analysis of the interaction between the eukaryotic chaperonin CCT and its substrates actin and tubulin.	ACTA1 ACTA2	6.44e-05	5	89	2	11580270
Interaction	PDE6B interactions	GLI2 PYGB CHN2 SYNGAP1	6.46e-06	29	85	4	int:PDE6B
Cytoband	1q42.13	PRSS38 ACTA1 URB2	1.22e-04	49	89	3	1q42.13
Cytoband	15q21	TRPM7 RNF111	2.02e-04	11	89	2	15q21
Cytoband	2q34	PIKFYVE ABCA12	1.36e-03	28	89	2	2q34
GeneFamily	Actins	ACTA1 ACTA2 ACTC1	7.26e-07	6	61	3	929
GeneFamily	7TM orphan receptors	GPR143 GPR108	1.67e-04	6	61	2	310
Coexpression	GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN	TBX19 PTPN13 NF1 NEK6 MYO1C ACVR2A GPR108	4.78e-06	198	88	7	M6511
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	PTPN13 NF1 PARD3B RERE NR6A1 XKR6 AGBL1	1.46e-07	198	89	7	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3C MYO7B MYH14 ABCA12 MGAT4C SGK2	1.46e-06	176	89	6	7622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-SST-MGE1-4\|World / Primary Cells by Cluster	ZNF608 MYCBP2 SP9 ST8SIA5 RERE PTPRT	2.49e-06	193	89	6	2eb6e4cff4fe3ce564c1581f6f7df4834895aaa9
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-6\|TCGA-Lung / Sample_Type by Project: Shred V9	HMCN2 STARD9 NXF3 ACTC1 AGBL1	5.47e-06	126	89	5	b49b15ba1458488f98d54e87100257a12ee34076
ToppCell	metastatic_Brain-Fibroblasts-Smooth_muscle_cells\|Fibroblasts / Location, Cell class and cell subclass	ACTA2 ACTC1 PGAP4 XKR6 TTLL7	1.45e-05	154	89	5	423f58fc7dcef068458cbf7b4ee989e37227041e
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	EPPK1 HMCN2 ACTA2 UTRN TTLL7	1.80e-05	161	89	5	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	15-Airway-Mesenchymal-Airway_Smooth_Muscle\|Airway / Age, Tissue, Lineage and Cell class	SEMA3C ACTA2 ACTC1 SLITRK3 CHN2	2.02e-05	165	89	5	531804467601e1ee1f771cffa21501f6d464ae10
ToppCell	facs-Large_Intestine-Proximal\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 ARHGAP20 CHN2 MGAT4C SGK2	2.20e-05	168	89	5	23e0e1592d7400012d289adb10c7598285bae2e9
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3C MYO7B ABCA12 MGAT4C SGK2	2.40e-05	171	89	5	5d0d6c1ff610a703ae0b834a12823c5ff9012932
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3C ABCA12 ACTA2 ARHGAP20 MGAT4C	2.54e-05	173	89	5	e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCell	facs-Large_Intestine-Proximal-3m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3C ABCA12 ACTA2 ARHGAP20 MGAT4C	2.54e-05	173	89	5	99532bb768ee35fed939a377acb5215d3f8904bd
ToppCell	ASK454-Epithelial-Ciliated\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	USP51 STARD9 PRR29 CFAP57 TTLL7	2.99e-05	179	89	5	f21919ef9d3d984e2925ef3d24f89e20fe265dcd
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SEMA3C ACTA2 ACTC1 GPR143 SLITRK3	3.32e-05	183	89	5	a1d4f25e13f5b9e92a9ca0a804a7bed5df8fb2fe
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 MYO7B PRR29 CFAP57 PPP1R42	3.32e-05	183	89	5	6ca7c2d7c56e0f1b9038ba677b4c1c3dfd63bfce
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 MYO7B PRR29 CFAP57 PPP1R42	3.32e-05	183	89	5	18040d0653286071df959513c63d94b555a5d00a
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ZNF608 MYH14 NR6A1 XKR6 AGBL1	3.59e-05	186	89	5	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPN13 MYH14 PKHD1 NR6A1 UTRN	3.59e-05	186	89	5	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	PTPN13 ZNF608 MYH14 NR6A1 AGBL1	3.68e-05	187	89	5	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 PKHD1 PARD3B RERE UTRN	3.87e-05	189	89	5	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPN13 GLI2 ACVR2A ARHGAP20 MMP19	3.87e-05	189	89	5	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF608 SP9 UTRN MGAT4C PTPRT	4.27e-05	193	89	5	294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF608 SP9 UTRN MGAT4C PTPRT	4.27e-05	193	89	5	3d3c45d5ff6f3396a1990615aae9fe176e799994
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF608 SP9 UTRN MGAT4C PTPRT	4.38e-05	194	89	5	6ac759828c41ffa974ee82842162caa959351dd1
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF608 SP9 UTRN MGAT4C PTPRT	4.38e-05	194	89	5	5d0b0d8e96f0e0297a4dba70a05d87081a4eb323
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 PKHD1 PARD3B RERE NR6A1	4.49e-05	195	89	5	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	PARD3B RERE NR6A1 XKR6 AGBL1	4.60e-05	196	89	5	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	Bronchial-NucSeq-Stromal-Mesofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SEMA3C FAM153B ABCA12 CYP3A43 MGAT4C	4.60e-05	196	89	5	96e5c6d155273e82ebafa180df8bb589c3e3e54e
ToppCell	Bronchial-NucSeq-Stromal-Mesofibroblastic-Mesothelia\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SEMA3C FAM153B ABCA12 CYP3A43 MGAT4C	4.60e-05	196	89	5	ce13af36fc2932e8125013041742593ff3d07e86
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTPN13 PKHD1 PARD3B RERE NR6A1	4.60e-05	196	89	5	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAM153B STARD9 ACTA2 SLITRK3 TTLL7	4.71e-05	197	89	5	ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCell	390C-Fibroblasts-Fibroblast-K_(Pericytes)\|390C / Donor, Lineage, Cell class and subclass (all cells)	MYO1C ACTA1 ACTA2 ACTC1 TTLL7	4.83e-05	198	89	5	c82a151f9f1477d4a401457173b8d72af776c137
ToppCell	390C-Fibroblasts-Fibroblast-K_(Pericytes)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	MYO1C ACTA1 ACTA2 ACTC1 TTLL7	4.83e-05	198	89	5	dc63b56bb6291e527b172d603569376286262845
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	NF1 PARD3B RERE XKR6 UTRN	4.94e-05	199	89	5	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	390C-Fibroblasts-Fibroblast-K_(Pericytes)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	MYO1C ACTA1 ACTA2 ACTC1 TTLL7	5.06e-05	200	89	5	2bc7f462a551292de2501028164573935232f899
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	NDST3 SEMA3C ACTA2 GPR143 MEIS3	5.06e-05	200	89	5	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ZNF608 SP9 PARD3B MGAT4C PTPRT	5.06e-05	200	89	5	e90155498397524b812c46f2412320230b445bb6
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Astrocyte\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	PTPN13 NEK6 GLI2 ACTA1 H6PD	5.06e-05	200	89	5	b9bd6c4381c92bfc1bfff9aa778a62a41d08f1ef
ToppCell	390C-Fibroblasts-Fibroblast-K_(Pericytes)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	MYO1C ACTA1 ACTA2 ACTC1 TTLL7	5.06e-05	200	89	5	8b80a65b69b36ed405214564b939452c90aa40d6
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature_-_proliferative\|E16.5-samps / Age Group, Lineage, Cell class and subclass	LYG2 ACTA2 CATSPERB CHN2	1.60e-04	136	89	4	96370f0e3abf1c9ec7a91595b5d0f97ac2ab4b78
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNNI3K SOX17 PKHD1 PTPRT	1.64e-04	137	89	4	b831d917f5073ccff158662adb281d34f023126a
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNNI3K SOX17 PKHD1 PTPRT	1.64e-04	137	89	4	cf3e928d9a7a7349840bb87475a42a07f65b94f0
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNNI3K SOX17 PKHD1 PTPRT	1.64e-04	137	89	4	5d82d6c7eef4ec7a7fae60e37fb956488314987e
ToppCell	TCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma_Heterologous_Type-4\|TCGA-Uterus / Sample_Type by Project: Shred V9	ACTA1 KLF14 ACTC1 AGBL1	1.69e-04	138	89	4	d1104a9f751ffa6970fd3096a4abf5bed30aa78f
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	HMCN2 STARD9 SP9 PARD3B	1.79e-04	140	89	4	2c44e8cc5190226049be7ebc465d685393e701c4
ToppCell	COVID-19_Severe-MAIT\|COVID-19_Severe / disease group, cell group and cell class	FAM153B PTPN13 TUBD1 SYNGAP1	2.33e-04	150	89	4	923ea7ecc0aa05fb0396082cd9c3d1594135f1e0
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NUP210L AGBL1 MGAT4C PTPRT	2.33e-04	150	89	4	0205318a870e091add66ee4305747dda9f51510d
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac1_Htr1d\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NDST3 TNNI3K SP9 PTPRT	2.63e-04	155	89	4	79264ff283e36a059040a5aa9fe7337be694cb52
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NDST3 PRSS38 HECW2 KLF14	2.63e-04	155	89	4	8fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCell	droplet-Fat-Mat-18m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH14 PKHD1 MGAT4C SGK2	2.70e-04	156	89	4	cfd7f56f3155db677684827607e9008e975dbe70
ToppCell	droplet-Fat-Mat-18m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH14 PKHD1 MGAT4C SGK2	2.70e-04	156	89	4	0d79b4172896574b00faf00e87254f68d76f5512
ToppCell	droplet-Fat-Mat-18m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH14 PKHD1 MGAT4C SGK2	2.70e-04	156	89	4	f09150aacb6121f913648ed3918f9cd4f22c61f2
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYH14 PKHD1 CFAP57 RNF111	2.77e-04	157	89	4	4766f7d545bf2d775390589460677519cb92f4d5
ToppCell	facs-Heart-Unknown-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH14 ACTA1 ACTC1 SGK2	2.77e-04	157	89	4	8d30d8e6fae93afcada6bd68799439335cd65b69
ToppCell	facs-Heart-Unknown-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH14 ACTA1 ACTC1 SGK2	2.77e-04	157	89	4	2ac4695d9e4ca8d4ba19c555e9a1d86ac8f398ab
ToppCell	facs-Heart-Unknown-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH14 ACTA1 ACTC1 SGK2	2.77e-04	157	89	4	8a393eece90fb9a1b7c356736bdb36277261fbd3
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	NUP210L AGBL1 MGAT4C PTPRT	2.90e-04	159	89	4	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	Ciliated_cells-A-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	PRR29 CFAP57 PPP1R42 PTPRT	2.90e-04	159	89	4	0c65ae6140abd48c79b04758a6217709ddd15385
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B ABCA12 PKHD1 PTPRT	2.97e-04	160	89	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	EPPK1 ACTA2 UTRN TTLL7	2.97e-04	160	89	4	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	facs-Heart-RV-24m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX19 PKHD1 ACTC1 SP9	2.97e-04	160	89	4	41d6c811c445c0ba9b6a2deb10a3b6b793172582
ToppCell	facs-Heart-RV-24m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX19 PKHD1 ACTC1 SP9	2.97e-04	160	89	4	c1d03c0ac9c12615a06499209fcdf18e9b6f1fba
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B ABCA12 PKHD1 PTPRT	2.97e-04	160	89	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TNNI3K ACTA2 SLITRK3 PPP1R42	3.04e-04	161	89	4	8aade4da418d280fec393a3032cc163909408a69
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HMCN2 MYH14 NR6A1 TTLL7	3.12e-04	162	89	4	34b4cd3d2258f88dfbd6d32abd1db87aff8a6b6f
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	ERCC2 FAM153B PTPN13 XKR6	3.12e-04	162	89	4	2259e9536147e9cdee772e3a30ba7d104573262c
ToppCell	facs-SCAT-Fat-18m-Epithelial\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH14 ABCA12 MGAT4C SGK2	3.12e-04	162	89	4	341fa357ad7bdbef30864e8062f161e60185ffc9
ToppCell	facs-SCAT-Fat-18m-Epithelial-epithelial_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH14 ABCA12 MGAT4C SGK2	3.12e-04	162	89	4	7215f6eb2b65dea455e2eec722a9c38e6958b120
ToppCell	facs-SCAT-Fat-18m-Epithelial-nan\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH14 ABCA12 MGAT4C SGK2	3.12e-04	162	89	4	7fa93efa2039d68a4e8214fa143bcd3368349a2d
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FAM153B ZNF608 NR6A1 AGBL1	3.12e-04	162	89	4	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	NUP210L AGBL1 MGAT4C PTPRT	3.19e-04	163	89	4	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HMCN2 MYO1C MYH14 TTLL7	3.19e-04	163	89	4	56b8668dbf06faa6866ec71f29b92907b73f074d
ToppCell	COVID-19-lung-Mesothelial\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SEMA3C FAM153B GLI2 MGAT4C	3.26e-04	164	89	4	83303e2ba52008391b8dc3fae8225ab5bcb20063
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 BTNL2 MGAT4C SGK2	3.34e-04	165	89	4	ce79d217df88035457cd58f679e72dd98722ae22
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 BTNL2 MGAT4C SGK2	3.42e-04	166	89	4	22b31acbbef1936ce19b393cf880c63ea2fa0f1b
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ERCC2 FAM153B PTPN13 XKR6	3.42e-04	166	89	4	89e2b8453180983533faccb4275867861876d7ee
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCA12 SP9 PARD3B AGBL1	3.58e-04	168	89	4	2eed7dc1a2aff11be024823c4323c42bc94362f6
ToppCell	Adult-Mesenchymal-chondrocyte-D175\|Adult / Lineage, Cell type, age group and donor	HMCN2 GLI2 LARS1 UROD	3.58e-04	168	89	4	14071b961c9bdb54a8259b12a88237b802cbde36
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium-7\|TCGA-Endometrium / Sample_Type by Project: Shred V9	STARD9 SLITRK3 MEIS3 ARHGAP20	3.58e-04	168	89	4	a97e8e07ba949b30805aeed5f60fa5e092b9d3d4
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-ABC_aged-B_naive\|bone_marrow / Manually curated celltypes from each tissue	TBX19 ZNF608 MYO7B URB2	3.82e-04	171	89	4	fcc31a9a69f96de10d1324a5a4fbfe4289bf4984
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRR29 NR6A1 PTPRT SYNGAP1	3.82e-04	171	89	4	1854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCell	Severe-B_naive-8\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MYO1C ZNF608 MYO7B UTRN	4.08e-04	174	89	4	f3f8c924420f46321bd47e2b97f18c7241541599
ToppCell	PCW_13-14-Epithelial-Epithelial_ciliated\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PRR29 CFAP57 PPP1R42 PTPRT	4.17e-04	175	89	4	b1369d2b74f461e6822d0c33e9b50fe0dfbceb54
ToppCell	PCW_13-14-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PRR29 CFAP57 PPP1R42 PTPRT	4.17e-04	175	89	4	c82ec6deb6ccdd991a69a62b6d62d5b14c803d7a
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA3C ZNF608 HECW2 SOX17	4.26e-04	176	89	4	269326c2bf44a9003d95bc6dbc839f08f25737ca
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3C GLI2 MEIS3 MMP19	4.26e-04	176	89	4	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3C GLI2 MEIS3 MMP19	4.26e-04	176	89	4	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_B-GC_B_(II)\|lymph-node_spleen / Manually curated celltypes from each tissue	SPRED2 NEK6 ZNF608 GPR143	4.26e-04	176	89	4	5788dd5b23ebb52f19d3b5bdbcfe25dee349cf77
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ERCC2 ACTA1 ACTA2 ACTC1	4.26e-04	176	89	4	4ed73c73972334f6dc4229920205547823252fa0
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-nan\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGAP4 ARHGAP20 CHN2 MGAT4C	4.26e-04	176	89	4	1dd54bfaa58541de51e5a8328651d390833bd480
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPN13 MYH14 ARHGAP20 UTRN	4.36e-04	177	89	4	b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SEMA3C SP9 PARD3B AGBL1	4.36e-04	177	89	4	2b675840b7d2bb536c2c600936733bd9e97e7120
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2-Excitatory_Neuron.Slc17a6-Slc17a7-Slc17a8.Fezf2.Slc17a8_(Deep_layer_pyramidal_cells-Layer_5b)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TNNI3K ABCA12 NXF3	4.38e-04	74	89	3	e6c8b8046948a205e996e585f983fd0af80d5491
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PTPN13 ZNF608 MYH14 NR6A1	4.45e-04	178	89	4	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_2\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	ACTA2 ACTC1 SP9 ST8SIA5	4.54e-04	179	89	4	d95367d689732ab2653e8d70d8d8e5eb15ae6eef
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SEMA3C GLI2 ACTA2 GPR143	4.54e-04	179	89	4	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	droplet-Liver-LIVER_HEP-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 HECW2 PARD3B TTLL7	4.64e-04	180	89	4	dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EPPK1 PRR29 CFAP57 TTLL7	4.64e-04	180	89	4	92fb01b91261b3103454924cde56add337b41844
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	USP51 PRSS38 ACTA2 SOX17	4.64e-04	180	89	4	455d1e3ccf2ab609954f3b870e8f514ddca735f4
ToppCell	droplet-Liver-LIVER_HEP\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 HECW2 PARD3B TTLL7	4.64e-04	180	89	4	423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CHN2 UTRN MGAT4C PTPRT	4.64e-04	180	89	4	a407376209d80177bf7fc4200219030c83cb5f14
Drug	Flunixin meglumine [42461-84-7]; Up 200; 8.2uM; MCF7; HT_HG-U133A	TBX19 ERCC2 MYH14 ABCA12 GLI2 ACTA1 GPR143 NR6A1 UTRN	7.92e-08	197	89	9	3411_UP
Drug	MAPS	METAP1 SEMA3C ACTA1 ACTA2 ACTC1 UROD TUBD1	1.01e-05	191	89	7	CID000066161
Drug	Natamycin [7681-93-8]; Up 200; 6uM; MCF7; HT_HG-U133A	TBX19 NF1 PDHA2 CATSPERB RERE UROD ZNF236	1.28e-05	198	89	7	3548_UP
Drug	Galanthamine hydrobromide [1953-04-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A	NDST3 TBX19 MYH14 GPR143 NR6A1 UROD SGK2	1.32e-05	199	89	7	2787_UP
Drug	plakin	ACTA1 ACTA2 ACTC1 UTRN MGAT4C	1.75e-05	82	89	5	CID000018752
Disease	Moyamoya disease (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	1.32e-06	8	86	3	DOID:13099 (implicated_via_orthology)
Disease	autosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	1.32e-06	8	86	3	DOID:0110550 (implicated_via_orthology)
Disease	Baraitser-Winter syndrome 1 (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	1.32e-06	8	86	3	DOID:0081112 (implicated_via_orthology)
Disease	thoracic aortic aneurysm (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	1.32e-06	8	86	3	DOID:14004 (implicated_via_orthology)
Disease	intestinal atresia (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	2.83e-06	10	86	3	DOID:10486 (implicated_via_orthology)
Disease	patent ductus arteriosus (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	2.83e-06	10	86	3	DOID:13832 (implicated_via_orthology)
Disease	loneliness measurement	BTNL2 RERE CHN2 AGBL1 UTRN	3.21e-05	124	86	5	EFO_0007865
Disease	neuroimaging measurement, brain volume measurement	NF1 PYGB CATSPERB XKR6 TUBD1 C17orf58	1.93e-04	286	86	6	EFO_0004346, EFO_0006930
Disease	Colorectal Carcinoma	NDST3 TNNI3K ERCC2 NF1 TRPM7 ABCA12 SOX17 PKHD1 PTPRT	2.09e-04	702	86	9	C0009402
Disease	diet measurement	NF1 ZNF608 NUP210L HECW2 LPA PKHD1 RERE XKR6 KHDC4 AGBL1 PTPRT	2.33e-04	1049	86	11	EFO_0008111
Disease	hip circumference	TNNI3K NF1 TRPM7 KLF14 H6PD PTPRT	4.71e-04	338	86	6	EFO_0005093
Disease	C-reactive protein measurement	METAP1 ERCC2 NEK6 ZNF608 NUP210L LPA SP9 PYGB RERE XKR6 TUBD1	7.50e-04	1206	86	11	EFO_0004458
Disease	Moyamoya Disease	NF1 ACTA2	1.11e-03	17	86	2	C0026654
Disease	osteoarthritis, knee	EPPK1 BTNL2 PARD3B XKR6	1.19e-03	158	86	4	EFO_0004616
Disease	neuroticism measurement	NDST3 NEK6 ACTA1 PKHD1 ST8SIA5 RERE XKR6 ACVR2A AGBL1	1.33e-03	909	86	9	EFO_0007660
Disease	monocyte count	NF1 SPRED2 NEK6 MYO1C ZNF608 TRPM7 LPA ACVR2A DPP8 TUBD1 SGK2	1.55e-03	1320	86	11	EFO_0005091
Disease	neutrophil count	TBX19 SPRED2 NEK6 MYO1C COPA MYCBP2 NUP210L SMIM29 RERE XKR6 DPP8	2.23e-03	1382	86	11	EFO_0004833
Disease	venous thromboembolism	BTNL2 CATSPERB PARD3B H6PD AGBL1 PTPRT	2.28e-03	460	86	6	EFO_0004286
Disease	mean reticulocyte volume	FBXO38 SPRED2 NUP210L ENPP5 URB2 DPP8 TUBD1 SESN1	2.31e-03	799	86	8	EFO_0010701

Protein segments in the cluster

Peptide	Gene	Start	Entry
PPYHVHYFLVLLSMA	URB2	911	Q14146
PVGMVFHPRSHFLYA	CATSPERB	411	Q9H7T0
HRYPAVHVYMDGDHV	BTNL2	286	Q9UIR0
PIYEGYALPHAIMRL	ACTA1	166	P68133
HGIIMYSHPYPGVQD	ABCA12	1961	Q86UK0
YRHHKMAYPPVLVPT	ACVR2A	161	P27037
PIYEGYALPHAIMRL	ACTA2	166	P62736
QPYPLPHVRHMAYQL	CLK3	401	P49761
PGHHGYMLLDPVRSY	AMER1	431	Q5JTC6
GERRYSMPPLFHTHY	TENT2	111	Q6PIY7
THLKRVPFHDPYLYM	AGBL1	501	Q96MI9
MGYAVAPHHSGVYPV	NDST3	416	O95803
IMSYVPPHALLHPSY	HECW2	1146	Q9P2P5
HRYIANLGHGLYPDM	UROD	331	P06132
AGRLMVIHAPEEYYP	MGAT4C	166	Q9UBM8
HGAHMDSPVRYTPYT	NXF3	56	Q9H4D5
KERELPYYPGAHPMH	PARD3B	1106	Q8TEW8
SYIQRPDYADHPLGM	METAP1	101	P53582
APLVSMAPRIHGYLH	HMCN2	426	Q8NDA2
EPAHFEYLMYPLHSA	CFAP57	376	Q96MR6
PGSRYIVMGHIYHKR	C17orf58	276	Q2M2W7
PPHVYAVTEGAYRSM	MYH14	171	Q7Z406
SQALMAPVYEGYRPH	MMP19	226	Q99542
MVPLAYYGQHFVPLD	CSNKA2IP	1	A0A1B0GTH6
VPTPHFHYIMKYGVH	ENPP5	46	Q9UJA9
IHKRFPTHYMPYNES	ENPP5	146	Q9UJA9
SLVGTPYYMSPERIH	NEK6	206	Q9HC98
MARRYDELPHYPGIV	MEIS3	1	Q99687
VHHYGRAVIMFGVPY	ERCC2	611	P18074
PLPIDMRHQEGRYHY	GLI2	61	P10070
YHPERLQHYINPEPM	PGAP4	246	Q9BRR3
RDPRLHTPMYYFLCH	OR2I1P	51	Q8NGU4
ILHPTYEMYHPIGGD	PRSS38	136	A1L453
YHRPRHYIATQGPMQ	PTPRT	951	O14522
MPDVEQLYGLHPRYL	FBXO38	101	Q6PIJ6
PPAHYETLRYLMIHL	CHN2	396	P52757
PDKHYLMYEHERVPI	PIKFYVE	1646	Q9Y2I7
PPVHISIMEGHYYDP	CASC3	536	O15234
GLAVMVPIYALHHDP	CYP3A43	391	Q9HB55
RERPAYAVHGNMLHY	COPA	321	P53621
PDGPHSDRIYYLAMS	DPP8	91	Q6V1X1
RGLDHAIPHYVTMYL	GPR143	186	P51810
HSRTPEYYPNAGLIM	LPA	516	P08519
SMKPHLHPRLYHGCY	LYG2	26	Q86SG7
GREAFEPMYIYISHP	KHDC4	286	Q7Z7F0
RHPTYHPDMIEYRGR	KLF14	276	Q8TD94
LQHVRIPYYNIHPMP	H6PD	641	O95479
HPGHIYPRVASMEDY	FAM153B	46	P0C7A2
RHPGMADYIPVAVEH	NUP210L	1466	Q5VU65
PEVHGVSYFRMEHYL	PTPN13	716	Q12923
APMPDIQVYGYLLHT	MOXD2P	376	A6NHM9
GPILMELQTYRYHGH	PDHA2	276	P29803
GMSVPPHYQYIPHLF	NR6A1	216	Q15406
PLIGHEYPYGIKMSH	ARHGAP20	256	Q9P2F6
MTYKHPHVLPYRENL	UTP20	961	O75691
GHKLHYPMVEYCIPT	UTRN	3106	P46939
LLAPPSALHVYYGAM	SOX17	286	Q9H6I2
LQMDGPLPLHYRHYI	SESN1	106	Q9Y6P5
PLPLHYRHYIGIMAA	SESN1	111	Q9Y6P5
GAVLYEMLHGLPPFY	SGK2	221	Q9HBY8
IRNHPLMYNSIYPIH	SEMA3C	401	Q99985
PYPYMNGRLHLGHTF	LARS1	51	Q9P2J5
KTMHHIVPVYYPQVG	PPP1R42	271	Q7Z4L9
GHPIEGLAVMYYIAH	GPR108	321	Q9NPR9
VGHVYEYIPHPVTQM	SLITRK3	736	O94933
HHLPMPVAIQRGYVD	EPPK1	1056	P58107
RHHLLPMYSYDPAEE	SMIM29	51	Q86T20
HYYDNVKPRPGFHAM	ST8SIA5	336	O15466
ESHPYPVTYHMRQAH	MYCBP2	3246	O75592
MYYLEAEHHGIAPSR	PKHD1	451	P08F94
AYHMPGLYNVDPTIR	RERE	1286	Q9P2R6
EHEMLRHPVFGTPYP	RERE	1486	Q9P2R6
YTLRVREHPEMGPYV	STARD9	171	Q9P2P6
AADGLYPRVGMAHPY	SP9	141	P0CG40
PIYEGYALPHAIMRL	ACTC1	166	P68032
YGYSVHGPRHEESIM	TUBD1	106	Q9UJT1
HAMYSGSRTPHIPYK	USP51	416	Q70EK9
MLLYYGVLHPTGPRA	XKR6	491	Q5GH73
HPYVCAGLMHPYDGK	nan	506	Q6ZTK2
VPDMAGYPHIRYISS	RNF111	851	Q6ZNA4
GPSMHRTQYVHSPYD	SYNGAP1	26	Q96PV0
MSPVLHFYVRPSGHE	PFAS	1	O15067
RHKHTPVYHPRVYTG	ZIK1	221	Q3SY52
EKARPEYMLPVHFYG	PYGB	191	P11216
EYMLPVHFYGRVEHT	PYGB	196	P11216
VPMDTYPIHHGDPSY	NF1	2471	P21359
SYPTDHYHLDQPMPR	SPRED2	186	Q7Z698
HYHLDQPMPRPYRQV	SPRED2	191	Q7Z698
AYRAVSPVLMHSYPG	ZNF608	1361	Q9ULD9
HMGIHNDLRPYMCPY	ZNF236	731	Q9UL36
LVFHHHYLPYLMPSP	PRR29	106	P0C7W0
RGHRQAPYPSAYMHR	TBX19	286	O60806
DMAYHHIRPPIGYSI	TNNI3K	676	Q59H18
YHFIMAYHEKPVLPP	TRPM7	1116	Q96QT4
HENRHMGNYRRIYPP	TTLL7	446	Q6ZT98
MERYRGVSFYEVPPH	MYO1C	101	O00159
LYYSRHMGELPPHVF	MYO7B	121	Q6PIF6