Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	CACNA1A CACNB2 KCNA4 KCNC4 KCND2 CACNG4 CACHD1	4.89e-06	152	88	7	GO:0022843
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1A CACNB2 KCNA4 KCNC4 KCND2 CACNG4 CACHD1	1.59e-05	182	88	7	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1A CACNB2 KCNA4 KCNC4 KCND2 CACNG4 CACHD1	1.70e-05	184	88	7	GO:0022832
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1A CACNB2 CACNG4 CACHD1	4.99e-05	46	88	4	GO:0005245
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA1A CACNB2 KCNA4 KCNC4 KCND2 CACNG4 CACHD1 SLC23A1 SLC30A6	2.09e-04	465	88	9	GO:0046873
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	KCNC4 KCND2	2.85e-04	6	88	2	GO:1905030
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	CACNA1A CACNB2 KCNA4 KCNC4 KCND2 CACNG4 CACHD1 SLC23A1 NDUFS1 SLC30A6	4.33e-04	627	88	10	GO:0022890
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CACNA1A CACNB2 KCNA4 KCNC4 KCND2 CACNG4 CACHD1 SLC23A1 NDUFS1 SLC30A6	6.75e-04	664	88	10	GO:0008324
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	CACNA1A CACNB2	6.78e-04	9	88	2	GO:0099511
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	CACNA1A CACNB2	6.78e-04	9	88	2	GO:0099626
GeneOntologyMolecularFunction	gated channel activity	CACNA1A CACNB2 KCNA4 KCNC4 KCND2 CACNG4 CACHD1	6.85e-04	334	88	7	GO:0022836
GeneOntologyMolecularFunction	monoatomic cation channel activity	CACNA1A CACNB2 KCNA4 KCNC4 KCND2 CACNG4 CACHD1	8.01e-04	343	88	7	GO:0005261
GeneOntologyMolecularFunction	metal-dependent deubiquitinase activity	EIF3F PRPF8	1.23e-03	12	88	2	GO:0140492
GeneOntologyMolecularFunction	transporter activity	CACNA1A CACNB2 KCNA4 KCNC4 KCND2 CETP PITPNM3 ATP9B CACNG4 CACHD1 SLC23A1 SLC7A14 NDUFS1 SLC30A6	1.46e-03	1289	88	14	GO:0005215
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1A CACNB2	1.69e-03	14	88	2	GO:0008331
GeneOntologyMolecularFunction	calcium channel regulator activity	CACNB2 NPY2R CACNG4	1.74e-03	54	88	3	GO:0005246
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	CACNA1A CACNB2 KCNA4 KCNC4 KCND2 CACNG4 CACHD1 SLC23A1 NDUFS1 SLC30A6	1.83e-03	758	88	10	GO:0015318
GeneOntologyCellularComponent	plasma membrane protein complex	CACNA1A CACNB2 CDH26 KCNA4 KCNC4 KCND2 HLA-DRB5 IRS1 CACNG4 CACHD1 ITGA1 ITGB3 IL6ST	2.70e-05	785	89	13	GO:0098797
GeneOntologyCellularComponent	voltage-gated calcium channel complex	CACNA1A CACNB2 CACNG4 CACHD1	4.37e-05	46	89	4	GO:0005891
GeneOntologyCellularComponent	cation channel complex	CACNA1A CACNB2 KCNA4 KCNC4 KCND2 CACNG4 CACHD1	6.54e-05	235	89	7	GO:0034703
GeneOntologyCellularComponent	glutamatergic synapse	CACNA1A EEF2 KCNA4 KCNC4 KCND2 ELAVL2 NTN1 LRRC7 NR3C2 CACNG4 GRM5 ITGB3	1.75e-04	817	89	12	GO:0098978
GeneOntologyCellularComponent	axon initial segment	KCNA4 NAV1 LRRC7	2.52e-04	29	89	3	GO:0043194
GeneOntologyCellularComponent	calcium channel complex	CACNA1A CACNB2 CACNG4 CACHD1	2.67e-04	73	89	4	GO:0034704
GeneOntologyCellularComponent	postsynaptic membrane	CACNA1A KCNA4 KCNC4 KCND2 LRRC7 CACNG4 GRM5 ITGB3	3.33e-04	405	89	8	GO:0045211
GeneOntologyCellularComponent	cilium	CCSAP DNAH3 TAS2R4 NPY2R FBXL13 IFT172 MYO3B DNAH2 AKAP3 IRS1 ADGRV1 MORN5	4.15e-04	898	89	12	GO:0005929
GeneOntologyCellularComponent	inner dynein arm	DNAH3 DNAH2	7.89e-04	10	89	2	GO:0036156
GeneOntologyCellularComponent	neuronal cell body membrane	KCNC4 KCND2 IL6ST	8.14e-04	43	89	3	GO:0032809
GeneOntologyCellularComponent	cell body membrane	KCNC4 KCND2 IL6ST	1.06e-03	47	89	3	GO:0044298
GeneOntologyCellularComponent	L-type voltage-gated calcium channel complex	CACNB2 CACNG4	1.15e-03	12	89	2	GO:1990454
GeneOntologyCellularComponent	monoatomic ion channel complex	CACNA1A CACNB2 KCNA4 KCNC4 KCND2 CACNG4 CACHD1	1.16e-03	378	89	7	GO:0034702
GeneOntologyCellularComponent	membrane protein complex	CACNA1A CACNB2 CDH26 KCNA4 KCNC4 KCND2 HLA-DRB5 APOOL IRS1 CACNG4 CACHD1 ITGA1 ITGB3 NDUFS1 IL6ST	1.56e-03	1498	89	15	GO:0098796
GeneOntologyCellularComponent	transmembrane transporter complex	CACNA1A CACNB2 KCNA4 KCNC4 KCND2 CACNG4 CACHD1 NDUFS1	1.74e-03	523	89	8	GO:1902495
Domain	Channel_four-helix_dom	CACNA1A KCNA4 KCNC4 KCND2	1.57e-04	57	89	4	IPR027359
Domain	-	CACNA1A KCNA4 KCNC4 KCND2	1.57e-04	57	89	4	1.20.120.350
Domain	K_chnl_volt-dep_Kv	KCNA4 KCNC4 KCND2	2.82e-04	27	89	3	IPR003968
Domain	EFG_III-V	GUF1 EEF2	3.33e-04	6	89	2	IPR009022
Domain	EFG_C	GUF1 EEF2	3.33e-04	6	89	2	SM00838
Domain	EFG_C	GUF1 EEF2	3.33e-04	6	89	2	PF00679
Domain	-	GUF1 EEF2	4.64e-04	7	89	2	3.30.70.240
Domain	EFG_V	GUF1 EEF2	4.64e-04	7	89	2	IPR000640
Domain	VG_K_chnl	KCNA4 KCNC4 KCND2	5.15e-04	33	89	3	IPR028325
Domain	G_TR_CS	GUF1 EEF2	7.91e-04	9	89	2	IPR031157
Domain	JAB_MPN	EIF3F PRPF8	1.44e-03	12	89	2	SM00232
Domain	JAMM/MPN+_dom	EIF3F PRPF8	1.44e-03	12	89	2	IPR000555
Domain	JAB	EIF3F PRPF8	1.44e-03	12	89	2	PF01398
Domain	G_TR_1	GUF1 EEF2	1.69e-03	13	89	2	PS00301
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DNAH2	1.97e-03	14	89	2	IPR024317
Domain	PB1	MAP3K3 MAP3K2	1.97e-03	14	89	2	SM00666
Domain	Dynein_HC_stalk	DNAH3 DNAH2	1.97e-03	14	89	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH3 DNAH2	1.97e-03	14	89	2	IPR013602
Domain	DHC_N2	DNAH3 DNAH2	1.97e-03	14	89	2	PF08393
Domain	MT	DNAH3 DNAH2	1.97e-03	14	89	2	PF12777
Domain	AAA_8	DNAH3 DNAH2	1.97e-03	14	89	2	PF12780
Domain	PB1	MAP3K3 MAP3K2	1.97e-03	14	89	2	PF00564
Domain	ATPase_dyneun-rel_AAA	DNAH3 DNAH2	1.97e-03	14	89	2	IPR011704
Domain	PB1	MAP3K3 MAP3K2	1.97e-03	14	89	2	PS51745
Domain	AAA_5	DNAH3 DNAH2	1.97e-03	14	89	2	PF07728
Domain	PB1_dom	MAP3K3 MAP3K2	1.97e-03	14	89	2	IPR000270
Domain	BTB_2	KCNA4 KCNC4 KCND2	2.06e-03	53	89	3	PF02214
Domain	T1-type_BTB	KCNA4 KCNC4 KCND2	2.06e-03	53	89	3	IPR003131
Domain	Ion_trans_dom	CACNA1A KCNA4 KCNC4 KCND2	2.16e-03	114	89	4	IPR005821
Domain	Ion_trans	CACNA1A KCNA4 KCNC4 KCND2	2.16e-03	114	89	4	PF00520
Domain	DHC_fam	DNAH3 DNAH2	2.26e-03	15	89	2	IPR026983
Domain	Dynein_heavy_dom	DNAH3 DNAH2	2.26e-03	15	89	2	IPR004273
Domain	Dynein_heavy	DNAH3 DNAH2	2.26e-03	15	89	2	PF03028
Domain	EFTu-like_2	GUF1 EEF2	3.27e-03	18	89	2	IPR004161
Domain	GTP_EFTU_D2	GUF1 EEF2	3.27e-03	18	89	2	PF03144
Domain	G_TR_2	GUF1 EEF2	3.27e-03	18	89	2	PS51722
Domain	-	PITPNM3 LHPP ATP9B	3.53e-03	64	89	3	3.40.50.1000
Domain	TF_GTP-bd_dom	GUF1 EEF2	3.64e-03	19	89	2	IPR000795
Pathway	REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING	CACNA1A CACNB2 CACNG4	1.88e-05	11	70	3	MM14498
Pathway	REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING	CACNA1A CACNB2 CACNG4	1.88e-05	11	70	3	M26913
Pathway	REACTOME_NEURONAL_SYSTEM	CACNA1A CACNB2 NAAA KCNA4 KCNC4 KCND2 LRRC7 CACNG4 GRM5	3.94e-05	335	70	9	MM14503
Pathway	REACTOME_NEURONAL_SYSTEM	CACNA1A CACNB2 NAAA KCNA4 KCNC4 KCND2 LRRC7 CACNG4 GRM5	1.88e-04	411	70	9	M735
Pathway	KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL	CACNA1A CACNB2 CACNG4	2.49e-04	25	70	3	M47948
Pubmed	A Novel Human CAMK2A Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors.	CACNB2 LRRC7 GRM5	1.39e-06	9	90	3	28130356
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	CACNA1A CACNB2 KCNA4 KCNC4 KCND2 CACNG4	1.73e-06	139	90	6	16985003
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PLCD3 FLNB GUF1 EEF2 WAPL HK2 NCKAP1 FUBP1 TAF1B EIF3F PRPF8 ELP3 NDUFS1 MED12 HIRA	1.94e-06	1353	90	15	29467282
Pubmed	Ion channel expression in the developing enteric nervous system.	CACNA1A KCNA4 KCNC4 KCND2	2.59e-06	37	90	4	25798587
Pubmed	The kinases MEKK2 and MEKK3 regulate transforming growth factor-β-mediated helper T cell differentiation.	MAP3K3 MAP3K2	6.62e-06	2	90	2	21333552
Pubmed	Platelet hyperreactivity after coronary artery bypass grafting: the possible relevance to glycoprotein polymorphisms. A preliminary report.	ITGA1 ITGB3	6.62e-06	2	90	2	11454259
Pubmed	Arachidonic acid potently inhibits both postsynaptic-type Kv4.2 and presynaptic-type Kv1.4 IA potassium channels.	KCNA4 KCND2	6.62e-06	2	90	2	19453640
Pubmed	Reduced excitability of gp130-deficient nociceptors is associated with increased voltage-gated potassium currents and Kcna4 channel upregulation.	KCNA4 IL6ST	6.62e-06	2	90	2	24463703
Pubmed	Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase.	MAP3K3 MAP3K2	6.62e-06	2	90	2	8621389
Pubmed	Lrrc7 mutant mice model developmental emotional dysregulation that can be alleviated by mGluR5 allosteric modulation.	LRRC7 GRM5	6.62e-06	2	90	2	31582721
Pubmed	Molecular basis of transient outward K+ current diversity in mouse ventricular myocytes.	KCNA4 KCND2	6.62e-06	2	90	2	10601491
Pubmed	Expression of alpha 1 and beta 3 integrins subunits in the endometrium of patients with tubal phimosis or hydrosalpinx.	ITGA1 ITGB3	6.62e-06	2	90	2	16412752
Pubmed	A Mediator-cohesin axis controls heterochromatin domain formation.	WAPL MED12	6.62e-06	2	90	2	35136067
Pubmed	Fubp1 supports the lactate-Akt-mTOR axis through the upregulation of Hk1 and Hk2.	HK2 FUBP1	1.98e-05	3	90	2	30871777
Pubmed	Pituitary adenylate cyclase activating polypeptide reduces expression of Kv1.4 and Kv4.2 subunits underlying A-type K(+) current in adult mouse olfactory neuroepithelia.	KCNA4 KCND2	1.98e-05	3	90	2	16426762
Pubmed	Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta.	MAP3K3 MAP3K2	1.98e-05	3	90	2	10085062
Pubmed	WNK1 activates ERK5 by an MEKK2/3-dependent mechanism.	MAP3K3 MAP3K2	1.98e-05	3	90	2	14681216
Pubmed	Molecular dissection of I(A) in cortical pyramidal neurons reveals three distinct components encoded by Kv4.2, Kv4.3, and Kv1.4 alpha-subunits.	KCNA4 KCND2	1.98e-05	3	90	2	20371829
Pubmed	Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans.	NAV2 NAV1	1.98e-05	3	90	2	12079279
Pubmed	Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53.	NAV2 NAV1	1.98e-05	3	90	2	15158073
Pubmed	Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3.	MAP3K3 MAP3K2	1.98e-05	3	90	2	14661019
Pubmed	Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms.	NAV2 NAV1	1.98e-05	3	90	2	12062803
Pubmed	I(A) channels encoded by Kv1.4 and Kv4.2 regulate neuronal firing in the suprachiasmatic nucleus and circadian rhythms in locomotor activity.	KCNA4 KCND2	1.98e-05	3	90	2	22815518
Pubmed	Recurrent chromosomal rearrangements of ROS1, FRK and IL6 activating JAK/STAT pathway in inflammatory hepatocellular adenomas.	FRK IL6ST	1.98e-05	3	90	2	31907296
Pubmed	A-type K+ channels encoded by Kv4.2, Kv4.3 and Kv1.4 differentially regulate intrinsic excitability of cortical pyramidal neurons.	KCNA4 KCND2	1.98e-05	3	90	2	22615428
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA1A CACNB2 EEF2 KCNA4 NCKAP1 NAV1 ELAVL2 LRRC7 CDC73 GRM5 HIRA	3.93e-05	963	90	11	28671696
Pubmed	MEKK2 and MEKK3 suppress Hedgehog pathway-dependent medulloblastoma by inhibiting GLI1 function.	MAP3K3 MAP3K2	3.96e-05	4	90	2	29662197
Pubmed	MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway.	MAP3K3 MAP3K2	3.96e-05	4	90	2	11073940
Pubmed	Implications of the differing roles of the β1 and β3 transmembrane and cytoplasmic domains for integrin function.	ITGA1 ITGB3	3.96e-05	4	90	2	27929375
Pubmed	IA Channels Encoded by Kv1.4 and Kv4.2 Regulate Circadian Period of PER2 Expression in the Suprachiasmatic Nucleus.	KCNA4 KCND2	3.96e-05	4	90	2	26152125
Pubmed	Human fallopian tube epithelium constitutively expresses integrin endometrial receptivity markers: no evidence for a tubal implantation window.	ITGA1 ITGB3	3.96e-05	4	90	2	22002573
Pubmed	Chromosomal mapping in the mouse of eight K(+)-channel genes representing the four Shaker-like subfamilies Shaker, Shab, Shaw, and Shal.	KCNA4 KCNC4 KCND2	4.17e-05	26	90	3	7905852
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	FAT2 CETP SUSD2 ITGA1 ITGB3 IL6ST	5.69e-05	257	90	6	16335952
Pubmed	Nonsyndromic Retinitis Pigmentosa Overview	NEUROD1 IFT172 PRPF8 SLC7A14	5.99e-05	81	90	4	20301590
Pubmed	PB1 domains of MEKK2 and MEKK3 interact with the MEK5 PB1 domain for activation of the ERK5 pathway.	MAP3K3 MAP3K2	6.59e-05	5	90	2	12912994
Pubmed	Differential recruitment of Kv1.4 and Kv4.2 to lipid rafts by PSD-95.	KCNA4 KCND2	6.59e-05	5	90	2	14559911
Pubmed	Identification of a cardiac isoform of the murine calcium channel alpha1C (Cav1.2-a) subunit and its preferential binding with the beta2 subunit.	CACNA1A CACNB2	6.59e-05	5	90	2	16787652
Pubmed	Tissue transglutaminase is an integrin-binding adhesion coreceptor for fibronectin.	ITGA1 ITGB3	6.59e-05	5	90	2	10684262
Pubmed	Integrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesions.	ITGA1 ITGB3	6.59e-05	5	90	2	23023225
Pubmed	Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling.	FLNB EEF2 WAPL PRPF8	7.92e-05	87	90	4	24169447
Pubmed	Cerebral cavernous malformation 2 protein promotes smad ubiquitin regulatory factor 1-mediated RhoA degradation in endothelial cells.	MAP3K3 MAP3K2	9.87e-05	6	90	2	19318350
Pubmed	PB1 domain interaction of p62/sequestosome 1 and MEKK3 regulates NF-kappaB activation.	MAP3K3 MAP3K2	9.87e-05	6	90	2	19903815
Pubmed	Interdependent roles for accessory KChIP2, KChIP3, and KChIP4 subunits in the generation of Kv4-encoded IA channels in cortical pyramidal neurons.	KCNA4 KCND2	9.87e-05	6	90	2	20943905
Pubmed	Targeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f).	KCNA4 KCND2	9.87e-05	6	90	2	18603586
Pubmed	MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42.	MAP3K3 MAP3K2	9.87e-05	6	90	2	9305638
Pubmed	Conditional and constitutive expression of a Tbx1-GFP fusion protein in mice.	NEUROD1 NTN1	9.87e-05	6	90	2	23971992
Pubmed	Identification of chromosomes associated with dental caries susceptibility using quantitative trait locus analysis in mice.	CACNA1A CACNB2	9.87e-05	6	90	2	14767162
Pubmed	Prevalence of genetic risk factors for coronary artery disease in Corsica island (France).	CETP ITGB3	9.87e-05	6	90	2	16248996
Pubmed	Quantitative trait locus that determines the cross-sectional shape of the femur in SAMP6 and SAMP2 mice.	PLCD3 CACNG4	9.87e-05	6	90	2	17295603
Pubmed	beta subunit reshuffling modifies N- and P/Q-type Ca2+ channel subunit compositions in lethargic mouse brain.	CACNA1A CACNB2	9.87e-05	6	90	2	10328888
Pubmed	Integrin and Arg-Gly-Asp dependence of cell adhesion to the native and unfolded triple helix of collagen type VI.	ITGA1 ITGB3	9.87e-05	6	90	2	8387021
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	EEF2 APOOL ELAVL2 EIF3F GTF2IRD1 PRPF8 NDUFS1 MED12 HIRA DHX8 ALPG	1.11e-04	1082	90	11	38697112
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	EEF2 KCNA4 NCKAP1 ELAVL2 LRRC7 ADGRV1 ELP3	1.30e-04	430	90	7	32581705
Pubmed	The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.	IRS1 ITGA1 ADGRV1 IL6ST	1.31e-04	99	90	4	19730683
Pubmed	Expression of astrocyte-related receptors in cortical dysplasia with intractable epilepsy.	KCND2 GRM5	1.38e-04	7	90	2	25003238
Pubmed	14-3-3 proteins interact with specific MEK kinases.	MAP3K3 MAP3K2	1.38e-04	7	90	2	9452471
Pubmed	Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.	DNAH3 DNAH2	1.38e-04	7	90	2	9256245
Pubmed	Identification and characterization of transcribed enhancers during cerebellar development through enhancer RNA analysis.	CACNA1A NEUROD1	1.38e-04	7	90	2	37365500
Pubmed	Remodeling of repolarization and arrhythmia susceptibility in a myosin-binding protein C knockout mouse model.	KCNA4 KCND2	1.38e-04	7	90	2	28646025
Pubmed	Barhl1 regulates migration and survival of cerebellar granule cells by controlling expression of the neurotrophin-3 gene.	NEUROD1 NTN1	1.38e-04	7	90	2	15044550
Pubmed	CYP A-204C polymorphism is associated with subclinical atherosclerosis in postmenopausal women.	CETP ITGB3	1.38e-04	7	90	2	18665040
Pubmed	Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension.	NAV2 NAV1	1.38e-04	7	90	2	25065758
Pubmed	Apolipoprotein E and paraoxonase 1 polymorphisms are associated with lower serum thyroid hormones in postmenopausal women.	CETP ITGB3	1.38e-04	7	90	2	19018779
Pubmed	Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.	MYO3B LHPP NR3C2 IRS1 CDC73	1.50e-04	193	90	5	22589738
Pubmed	International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.	KCNA4 KCNC4 KCND2	1.54e-04	40	90	3	16382104
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	CACNA1A FLNB HK2 KCNA4 NCKAP1 KCND2 PITPNM3 NAV1 LRRC7 GRM5 NDUFS1	1.73e-04	1139	90	11	36417873
Pubmed	GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain.	NPY2R GRM5	1.84e-04	8	90	2	9651375
Pubmed	The frequency of early, spontaneous miscarriage associated with the leu33pro polymorphism of Glycoprotein IIIa: a pilot study.	CETP ITGB3	1.84e-04	8	90	2	21039385
Pubmed	Methylenetetrahydrofolate reductase C677T polymorphism is associated with central adiposity and increased androgenicity in healthy postmenopausal women.	CETP ITGB3	1.84e-04	8	90	2	18728123
Pubmed	Knockout and knockin of the beta1 exon D define distinct roles for integrin splice variants in heart function and embryonic development.	ITGA1 ITGB3	1.84e-04	8	90	2	9553049
Pubmed	Developmental regulation of integrin expression at the time of implantation in the mouse embryo.	ITGA1 ITGB3	1.84e-04	8	90	2	8306881
Pubmed	TRAF7 potentiates MEKK3-induced AP1 and CHOP activation and induces apoptosis.	MAP3K3 MAP3K2	1.84e-04	8	90	2	15001576
Pubmed	N-terminal PDZ-binding domain in Kv1 potassium channels.	KCNA4 KCND2	1.84e-04	8	90	2	12435606
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	FLNB EEF2 WAPL HK2 CDC73	1.90e-04	203	90	5	22083510
Pubmed	Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation.	CACNA1A EEF2 FAT2	2.35e-04	46	90	3	34815492
Pubmed	Characterization of integrin engagement during defined human embryonic stem cell culture.	ITGA1 ITGB3	2.36e-04	9	90	2	19933311
Pubmed	Integrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment E8.	ITGA1 ITGB3	2.36e-04	9	90	2	1693624
Pubmed	Multiplex Chromosomal Exome Sequencing Accelerates Identification of ENU-Induced Mutations in the Mouse.	NCKAP1 IFT172	2.36e-04	9	90	2	22384391
Pubmed	Intensified antineoplastic effect by combining an HDAC-inhibitor, an mTOR-inhibitor and low dosed interferon alpha in prostate cancer cells.	ITGA1 ITGB3	2.36e-04	9	90	2	25808196
Pubmed	Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.	FLNB ITGB3	2.36e-04	9	90	2	11807098
Pubmed	RBR-type E3 ubiquitin ligase RNF144A targets PARP1 for ubiquitin-dependent degradation and regulates PARP inhibitor sensitivity in breast cancer cells.	PLCD3 EEF2 EIF3F	2.50e-04	47	90	3	29212245
Pubmed	Transcriptional analysis of Gli3 mutants identifies Wnt target genes in the developing hippocampus.	KCND2 ELAVL2 CACHD1	2.50e-04	47	90	3	22235033
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	FLNB EEF2 NCKAP1 IFT172 CDC73 EIF3F PRPF8 NDUFS1	2.54e-04	638	90	8	33239621
Pubmed	Insulin-like growth factor-1- and interleukin-6-related gene variation and risk of multiple myeloma.	IRS1 IL6ST	2.94e-04	10	90	2	19124510
Pubmed	Genetic predisposition to thrombophilia in inflammatory bowel disease.	CETP ITGB3	2.94e-04	10	90	2	20717043
Pubmed	The deubiquitinase OTUD1 regulates immunoglobulin production and proteasome inhibitor sensitivity in multiple myeloma.	FLNB PRPF8	2.94e-04	10	90	2	36357400
Pubmed	A novel cell migratory zone in the developing hippocampal formation.	NEUROD1 ELAVL2	2.94e-04	10	90	2	24771490
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	FLNB FUBP1 CDC73 ITGB3 NDUFS1 MAP3K2	3.54e-04	360	90	6	33111431
Pubmed	Characterization of the mitogen-activated protein kinase kinase 4 (MKK4)/c-Jun NH2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinases 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo.	MAP3K3 MAP3K2	3.59e-04	11	90	2	9162092
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	USP34 FRK FRRS1 TAF1B NDUFS1 ALPG	3.70e-04	363	90	6	14691545
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	FUBP1 CDC73 PRPF8 DHX8	3.71e-04	130	90	4	35545047
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	FRK FLNB WAPL NCKAP1 PRPF8 SLC7A14	4.15e-04	371	90	6	15747579
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	FRK LIMK2 FBXL13 MYO3B NR3C2 MAP3K2	4.21e-04	372	90	6	22939624
Pubmed	Genetic risk factors in typical haemolytic uraemic syndrome.	ITGB3 BDKRB2	4.30e-04	12	90	2	19110485
Pubmed	Ubiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1.	MAP3K3 MAP3K2	4.30e-04	12	90	2	24975362
Pubmed	Genetic influences on lipid metabolism trait variability within the Stanislas Cohort.	CETP ITGB3	4.30e-04	12	90	2	11714857
Pubmed	Identification of epilepsy genes in human and mouse.	CACNA1A ADGRV1	4.30e-04	12	90	2	11700294
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FLNB CACNB2 CDH26 FUBP1 NAV1 LHPP NTN1 ATP9B LRRC7 CHST11 ADGRV1 GTF2IRD1	4.53e-04	1489	90	12	28611215
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	CACNB2 KCNA4 NCKAP1 LRRC7 GRM5	5.02e-04	251	90	5	27507650
Pubmed	MEKK2 and MEKK3 orchestrate multiple signals to regulate Hippo pathway.	MAP3K3 MAP3K2	5.07e-04	13	90	2	33571521
Interaction	FLNA interactions	FLNB EEF2 WAPL NCKAP1 KCND2 CDC73 EIF3F PRPF8 GRM5 ITGB3 MAP3K3 MAP3K2 DHX8	4.00e-06	648	87	13	int:FLNA
Cytoband	2q32	NEUROD1 NCKAP1	3.41e-04	14	90	2	2q32
Cytoband	1p31.1	ST6GALNAC3 FUBP1 LRRC7	3.78e-04	71	90	3	1p31.1
GeneFamily	Calcium voltage-gated channel subunits	CACNA1A CACNB2 CACNG4	1.14e-04	26	66	3	253
GeneFamily	Potassium voltage-gated channels	KCNA4 KCNC4 KCND2	4.17e-04	40	66	3	274
GeneFamily	Dyneins, axonemal	DNAH3 DNAH2	1.72e-03	17	66	2	536
ToppCell	5'-Adult-SmallIntestine-Epithelial-neuro-epithelial-EECs\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A CACNB2 CDH26 NEUROD1 WDR97 CACNG4	9.63e-07	162	90	6	478cf560ef33c5c324142c76417447d4a571a2c9
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A FAT2 NEUROD1 KCNC4 KCND2 PITPNM3	2.15e-06	186	90	6	d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCell	COVID-19-lung-Secretory\|lung / Disease (COVID-19 only), tissue and cell type	FLNB FAT2 CDH26 NTN1 CACHD1 ADGRV1	2.36e-06	189	90	6	84d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A FAT2 NEUROD1 KCNC4 PITPNM3 CAMK2N2	2.36e-06	189	90	6	f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A FAT2 NEUROD1 KCNC4 KCND2 PITPNM3	2.66e-06	193	90	6	5fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A KCND2 NTN1 CHST11 CACNG4 GRM5	3.27e-06	200	90	6	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A KCND2 NTN1 CHST11 CACNG4 GRM5	3.27e-06	200	90	6	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A KCND2 NTN1 CHST11 CACNG4 GRM5	3.27e-06	200	90	6	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A KCND2 NTN1 CHST11 CACNG4 GRM5	3.27e-06	200	90	6	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A KCND2 NTN1 CHST11 CACNG4 GRM5	3.27e-06	200	90	6	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A KCND2 NTN1 CHST11 CACNG4 GRM5	3.27e-06	200	90	6	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	Cerebellum-Macroglia-OLIGODENDROCYTE-O1-Trf\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ADGRV1 ITGB3 SLC23A1 BDKRB2	8.15e-06	63	90	4	83e1c91f830aadaf13e13254ce30189fd434bcc9
ToppCell	Cerebellum-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendroyte.Trf.Il33_(Il33)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ADGRV1 ITGB3 SLC23A1 BDKRB2	8.15e-06	63	90	4	f2532b1aa117eea550f0ae0b599780c4fe621407
ToppCell	Cerebellum-Macroglia-OLIGODENDROCYTE-O1\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ADGRV1 ITGB3 SLC23A1 BDKRB2	8.15e-06	63	90	4	0643435edf3280daf38c950e5bec287a9d5cb517
ToppCell	Cerebellum-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendroyte.Trf.Il33_(Il33)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ADGRV1 ITGB3 SLC23A1 BDKRB2	8.15e-06	63	90	4	71c3afda6534401320791b714e3e2fe83094c914
ToppCell	facs-Heart-Unknown-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GALNAC3 MROH2A ELAVL2 LRRC7 TMEM30CP	1.03e-05	142	90	5	759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	HK2 WDR97 FUBP1 MYO3B MORN5	1.35e-05	150	90	5	98fdc6bdfde84d680e11d8727502b79afbf64303
ToppCell	droplet-Heart-nan-24m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A FBXL13 ADGRV1 SLC30A6 ARMH4	1.79e-05	159	90	5	7ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A CDH26 NEUROD1 SUSD2 SLC7A14	2.33e-05	168	90	5	17d46f993dc4ae22b8087808582aba77f5c61892
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK2 TLE6 NTN1 LRRC7 CACHD1	2.68e-05	173	90	5	c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	NPY2R KCNC4 ELAVL2 CAMK2N2 EPHA10	2.68e-05	173	90	5	7e3897868dd3f6e4974f593c60649a543ffc8693
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK2 TLE6 NTN1 LRRC7 CACHD1	2.68e-05	173	90	5	f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCell	5'-Adult-LargeIntestine-Epithelial-neuro-epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A CACNB2 NEUROD1 CAMK2N2 SLC7A14	2.75e-05	174	90	5	9f114e61458659005b6d0b4aa30a7a059e7aa5c6
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A NEUROD1 DCLK3 ADGRV1 SLC7A14	2.75e-05	174	90	5	a62531ebf16b32b249168dca11b870f63a8aa81c
ToppCell	COVID-19-kidney-CD-IC-A\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRK CACNB2 MYO3B ELAVL2 NTN1	2.91e-05	176	90	5	45028197364c64e93e3ffe86aff773d47a477d49
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A CACNB2 NEUROD1 CAMK2N2 ADGRV1	2.91e-05	176	90	5	da5933eb253f13e70296a50a2bb00ad5c19a2d99
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 FBXL13 WDR97 DNAH2 SLC7A14	3.15e-05	179	90	5	5e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A CACNB2 NEUROD1 NAV1 CAMK2N2	3.24e-05	180	90	5	9db9899ca42455310e9b63df523fe6c4780abfb7
ToppCell	Globus_pallidus-Neuronal-Inhibitory\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	NPY2R KCNC4 ELAVL2 CAMK2N2 EPHA10	3.41e-05	182	90	5	04ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB2 NEUROD1 KCNC4 ELAVL2 SLC7A14	3.59e-05	184	90	5	3da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A FAT2 NEUROD1 DCLK3 CAMK2N2	3.59e-05	184	90	5	7d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLCD3 FRK FLNB LIMK2 ST6GALNAC3	3.69e-05	185	90	5	87151ab95530e70d61328b336518df58db584acb
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRK CACNB2 NTN1 NR3C2 IRS1	3.78e-05	186	90	5	a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB2 NAAA MYO3B NAV2 ADGRV1	3.88e-05	187	90	5	7ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A FAT2 NEUROD1 PITPNM3 CAMK2N2	3.88e-05	187	90	5	1b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLNB KCNC4 NTN1 NR3C2 GTF2IRD1	3.88e-05	187	90	5	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CACNA1A NEUROD1 PITPNM3 KLHL35 ELAVL2	3.98e-05	188	90	5	e239bcdbd210a398a5850cb6fbf171d402f45a4f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB2 MYO3B NAV2 NR3C2 ADGRV1	3.98e-05	188	90	5	2ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRK CACNB2 NTN1 NR3C2 IRS1	3.98e-05	188	90	5	e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCND2 NTN1 CACNG4 GRM5 ARMH4	3.98e-05	188	90	5	a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCND2 NTN1 CACNG4 GRM5 ARMH4	3.98e-05	188	90	5	c8530c9ff98666c64a94683261af4288cb790a7e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLNB KCNC4 NTN1 NR3C2 GTF2IRD1	4.08e-05	189	90	5	e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	KCNA4 KCNC4 KCND2 DCLK3 ITGA1	4.40e-05	192	90	5	55f95454399fd533df75db06584eaa48d6ee3830
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRK KCNC4 NTN1 NR3C2 GTF2IRD1	4.40e-05	192	90	5	f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCell	Ciliated-cil-3\|World / Class top	DNAH3 CDH26 NAAA IFT172 DNAH2	4.40e-05	192	90	5	4989ebb8812b8af1870599acd932849122c05a29
ToppCell	COVID-19-lung-Secretory\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FAT2 CDH26 NTN1 CACHD1 ADGRV1	4.40e-05	192	90	5	59261098ccb52306f837f632ebaea45b90ad30fe
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	FAT2 CDH26 NCKAP1 NTN1 CACHD1	4.40e-05	192	90	5	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KCNA4 KCNC4 KCND2 DCLK3 ITGA1	4.40e-05	192	90	5	5000440dc1ed17e7474d340921bdff945646f27e
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	USP34 ATP9B CHST11 IL6ST ARMH4	4.51e-05	193	90	5	779276e775cb2492e8dd36436295a536084a6415
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELAVL2 LRRC7 GRM5 SLC7A14 EPHA10	4.51e-05	193	90	5	461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELAVL2 LRRC7 GRM5 SLC7A14 EPHA10	4.51e-05	193	90	5	0dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	USP34 FRK APOOL ADGRV1 NDUFS1	4.51e-05	193	90	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CETP ST6GALNAC3 NAV1 CHST11 CACHD1	4.51e-05	193	90	5	52e918884877b6659cdca0496390e440f73694a9
ToppCell	Children_(3_yrs)-Immune-monocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NAAA ST6GALNAC3 NAV1 CHST11 MAP3K3	4.74e-05	195	90	5	81a28289eda1a8a1a31b7357106f64ac5000e172
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CETP ST6GALNAC3 HLA-DRB5 NAV1 CHST11	4.85e-05	196	90	5	023312af38f816a44b407e0daa32590d953caf99
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	MYO3B NAV2 NR3C2 ADGRV1 GTF2IRD1	4.85e-05	196	90	5	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CACNA1A KCNA4 NAV1 CACNG4 GRM5	4.85e-05	196	90	5	f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CACNA1A KCNA4 NAV1 CACNG4 GRM5	4.85e-05	196	90	5	671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Deep_Layer-37\|World / Primary Cells by Cluster	NEUROD1 HLA-DRB5 NAV1 NR3C2 GRM5	4.97e-05	197	90	5	00d756bc0231e1b3b88430214338c1059cb11106
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	CCSAP NEUROD1 GLCE KLHL35 ELAVL2	5.09e-05	198	90	5	6d12ecaa9532c134d9c4562534dcb59a6420b4d3
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNB CDH26 ST6GALNAC3 NTN1 ADGRV1	5.09e-05	198	90	5	af399569c718f5fd971d73a7926768c9311002a3
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Immature_CPNs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	EEF2 DCLK3 KLHL35 ELAVL2 LRRC7	5.09e-05	198	90	5	32d58379a89be19b6b1a494bf033416546771c19
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like-IPs_and_early_cortical_neurons\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	CCSAP NEUROD1 GLCE KLHL35 ELAVL2	5.09e-05	198	90	5	7943e4f67c3d6efb5c8b00aa0ff3cfe7be10c48d
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNB CDH26 ST6GALNAC3 NTN1 ADGRV1	5.09e-05	198	90	5	1408e02e053ad3406229bfe8189da03be6366e81
ToppCell	NS-control-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FLNB FAT2 NCKAP1 NTN1 IL6ST	5.22e-05	199	90	5	32bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCell	Sepsis-URO-Lymphocyte-T/NK-dn_T\|URO / Disease, condition lineage and cell class	FLNB LIMK2 ANGEL1 ELP3 TOP3A	5.34e-05	200	90	5	04ea6381b93a5d8bbeda4d71c788d7fbac6d40bc
ToppCell	distal-3-Hematologic-Platelet/Megakaryocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DNAH3 IFT172 DNAH2 SLC23A1 MORN5	5.34e-05	200	90	5	f5f5a8b0e4d802d95dc42646dd5e7d7daaad72b4
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Neuron\|2m / Sample Type, Dataset, Time_group, and Cell type.	CCSAP NEUROD1 KLHL35 ELAVL2 ARMH4	5.34e-05	200	90	5	a581f1704a87b0390e1e2ff85053367d85247755
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_mature_2\|E18.5-samps / Age Group, Lineage, Cell class and subclass	KLHL35 NTN1 CAMK2N2 ARMH4	1.44e-04	131	90	4	f2eee150f5cff852e8f52f09b35e26f17d80833b
ToppCell	facs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MROH2A ELAVL2 LRRC7 TMEM30CP	1.92e-04	141	90	4	4aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCell	facs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MROH2A ELAVL2 LRRC7 TMEM30CP	1.92e-04	141	90	4	e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCell	COVID-19-kidney-Technical/muscle\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1A HORMAD2 DNAH3 KCND2	2.31e-04	148	90	4	0dbd87078f54ee1c2f8ec64e8bac9dfddb9c181e
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NPY2R MYO3B NTN1 SLC7A14	2.31e-04	148	90	4	5e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNB2 NEUROD1 ADGRV1 EPHA10	2.75e-04	155	90	4	498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CACNA1A NAV1 LRRC7 GRM5	2.75e-04	155	90	4	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-IPC_like\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	HORMAD2 NEUROD1 GLCE ELAVL2	2.82e-04	156	90	4	7e6805ebc7bc2f9c5965321d16922c155719970f
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-IPC_like-IPs_and_early_cortical_neurons\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	HORMAD2 NEUROD1 GLCE ELAVL2	2.82e-04	156	90	4	741de05295b2d012ac8576378f37709a97c8fb50
ToppCell	18-Distal-Epithelial-Basal_cell\|Distal / Age, Tissue, Lineage and Cell class	CACNA1A CDH26 MYO3B KLHL35	2.96e-04	158	90	4	183f445967e09e871c93d8e94781ed9fec894169
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1A DNAH3 KCND2 GRM5	3.03e-04	159	90	4	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	FRK FLNB HK2 EPHA10	3.03e-04	159	90	4	655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-neuro-epithelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A CDH26 NEUROD1 SUSD2	3.10e-04	160	90	4	6c89a2e4189e4f2b6b09b66c6aae6653785ab2f8
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	CACNA1A CACNB2 SUSD2 ITGA1	3.10e-04	160	90	4	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-DC1\|bone_marrow / Manually curated celltypes from each tissue	NAAA HLA-DRB5 NAV1 ELAVL2	3.18e-04	161	90	4	2f068ee643de2f647c289779a6624265ab9a749b
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ST6GALNAC3 NAV2 NTN1 ADGRV1	3.25e-04	162	90	4	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1A KCNA4 KCND2 ELAVL2	3.41e-04	164	90	4	be49af6335f2505065cde2cb9800e4a5516811b1
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A CACNB2 NEUROD1 ADGRV1	3.49e-04	165	90	4	4b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LHPP IRS1 MORN5 ARMH4	3.49e-04	165	90	4	1703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	ST6GALNAC3 ADGRV1 GTF2IRD1 MORN5	3.49e-04	165	90	4	3d2acdae0dd2b79a15f74158e8e566ce22b4218e
ToppCell	LV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	CACNA1A FRK CACNB2 ITGA1	3.49e-04	165	90	4	f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A CACNB2 NEUROD1 TLE6	3.57e-04	166	90	4	eb9c81fa7573de7aff6670e7dad313f02129809f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB2 KCNC4 NTN1 NR3C2	3.65e-04	167	90	4	edc5f04584b44f99ff9a62bbe0dab6fc044fb334
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NEUROD1 CAMK2N2 SLC7A14 EPHA10	3.73e-04	168	90	4	4e1b522c7400c9d87f63c00e4e1dd07136095cd6
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNA4 LRRC7 GRM5 SLC7A14	3.73e-04	168	90	4	b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A CACNB2 NEUROD1 CAMK2N2	3.73e-04	168	90	4	38ba7737ae0afffcbd3aa499403e83c24a922127
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNA4 LRRC7 GRM5 SLC7A14	3.73e-04	168	90	4	b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	LIMK2 TAF1B ANGEL1 SLC30A6	3.82e-04	169	90	4	29db25e7c5f31d98a08a35d7ec5ade203242bc50
ToppCell	10x5'v1-week_17-19-Myeloid_DC-DC-DC1\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	NAAA WDR97 HLA-DRB5 ADGRV1	3.82e-04	169	90	4	488ba50631a64cb9e0d69219491c66ac824c9e7d
ToppCell	343B-Myeloid-Dendritic-cDC_activated\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	FRK CACNB2 NTN1 MED12	3.82e-04	169	90	4	e68e6c24606fd46eca6f86bb63fa86ea17879ae2
ToppCell	10x5'v1-week_12-13-Myeloid_DC-DC-DC1\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	NAAA HLA-DRB5 MYO3B GTF2IRD1	3.82e-04	169	90	4	319511ea57bbd72c2d95e8516d093689df67a912
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related-Oligodendrocyte/OPC\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	LIMK2 TAF1B ANGEL1 SLC30A6	3.82e-04	169	90	4	b1611e61f635f8f9b87250e026ad30999cbee041
Drug	pyraclofos	CACNA1A CACNB2 HK2 KCNA4 KCNC4 KCND2 NAV1 CACNG4	8.73e-09	106	89	8	CID000093460
Drug	riluzole	CACNA1A CACNB2 KCNA4 NAV1 NTN1 CACNG4 GRM5	5.49e-06	174	89	7	CID000005070
Drug	LG100268	FLNB NEUROD1 NAAA GLCE IL6ST	7.52e-06	69	89	5	CID000003922
Drug	MK-825	CETP NR3C2	1.51e-05	2	89	2	CID000031855
Drug	Pilocarpine	CACNA1A NPY2R HK2 KCNC4 ITGA1 GRM5 ITGB3 BDKRB2	1.61e-05	285	89	8	ctd:D010862
Disease	Epilepsy, Benign Psychomotor, Childhood	NPY2R KCNC4 GRM5 BDKRB2	5.45e-07	23	85	4	C0393672
Disease	Epilepsy, Lateral Temporal	NPY2R KCNC4 GRM5 BDKRB2	5.45e-07	23	85	4	C0393682
Disease	Uncinate Epilepsy	NPY2R KCNC4 GRM5 BDKRB2	5.45e-07	23	85	4	C0014558
Disease	Epilepsy, Temporal Lobe	NPY2R KCNC4 GRM5 BDKRB2	5.45e-07	23	85	4	C0014556
Disease	self rated health	KCNC4 TAF1B HLA-DRB5	9.78e-05	31	85	3	EFO_0004778
Disease	childhood absence epilepsy (implicated_via_orthology)	CACNA1A NPY2R	1.22e-04	6	85	2	DOID:1825 (implicated_via_orthology)
Disease	Cocaine-Related Disorders	NPY2R ATP9B LRRC7 GRM5	3.71e-04	117	85	4	C0236736
Disease	Cocaine Abuse	NPY2R ATP9B LRRC7 GRM5	5.06e-04	127	85	4	C0009171
Disease	decanoylcarnitine measurement	ST6GALNAC3 DHX8	5.31e-04	12	85	2	EFO_0021039
Disease	Major Depressive Disorder	LHPP NR3C2 GRM5 BDKRB2 MED12	6.98e-04	243	85	5	C1269683
Disease	Cocaine Dependence	NPY2R ATP9B LRRC7 GRM5	7.11e-04	139	85	4	C0600427
Disease	Williams-Beuren syndrome (implicated_via_orthology)	LIMK2 GTF2IRD1	8.40e-04	15	85	2	DOID:1928 (implicated_via_orthology)
Disease	alcohol consumption measurement	CACNA1A HORMAD2 WAPL KCND2 IFT172 DNAH2 ELAVL2 NR3C2 ADGRV1 GRM5 ARMH4	8.64e-04	1242	85	11	EFO_0007878
Disease	Unipolar Depression	LHPP NR3C2 GRM5 BDKRB2 MED12	9.28e-04	259	85	5	C0041696
Disease	Astrocytosis	ITGA1 ITGB3	1.08e-03	17	85	2	C3887640
Disease	Lipidemias	CETP IRS1	1.08e-03	17	85	2	C1706412
Disease	Gliosis	ITGA1 ITGB3	1.08e-03	17	85	2	C0017639
Disease	Hyperlipidemia	CETP IRS1	1.08e-03	17	85	2	C0020473
Disease	response to mitochondrial complex I inhibitor	GLCE CHST11	1.36e-03	19	85	2	EFO_0600033
Disease	Hemorrhage	ITGB3 BDKRB2	1.51e-03	20	85	2	C0019080
Disease	cortical surface area measurement	CACNA1A USP34 FLNB FBXL13 NAV2 NAV1 ELAVL2 NTN1 NR3C2 CACHD1 ADGRV1	1.64e-03	1345	85	11	EFO_0010736
Disease	Infiltrating duct carcinoma of female breast	DCLK3 EPHA10	1.66e-03	21	85	2	C3165106
Disease	lung adenocarcinoma (is_marker_for)	EEF2 FUBP1 CDC73	1.92e-03	85	85	3	DOID:3910 (is_marker_for)
Disease	hypertension	PLCD3 CACNB2 LRRC7 NR3C2 GRM5	1.96e-03	307	85	5	EFO_0000537
Disease	depressive symptom measurement, response to antidepressant	NCKAP1 CACNG4 DHX8	2.12e-03	88	85	3	EFO_0007006, GO_0036276
Disease	age-related macular degeneration	FRK CETP GRM5	2.19e-03	89	85	3	EFO_0001365
Disease	arachidonic acid measurement	CACNA1A CHST11	2.36e-03	25	85	2	EFO_0006808
Disease	subcutaneous adipose tissue measurement	LHPP NR3C2 BDKRB2	2.48e-03	93	85	3	EFO_0004766
Disease	colorectal health	PITPNM3 NTN1 CHST11 ADGRV1	2.75e-03	201	85	4	EFO_0008460

Protein segments in the cluster

Peptide	Gene	Start	Entry
SEMFIKMYGLGTRPY	CACNA1A	531	O00555
PMLVFRTMKEYSDEG	BDKRB2	191	P30411
LLEKEAGMYPGTLMS	CDX4	6	O14627
SYPDITGEKAMMLLG	CETP	56	P11597
GFKIDTMGTYHGMTL	CDC73	306	Q6P1J9
DKAGYMSGMLVPVGV	ARMH4	706	Q86TY3
SMPLTLIREKGTYGM	ADGRV1	166	Q8WXG9
MGDGLIMTVSKPCYF	CACHD1	461	Q5VU97
GMESLKAMLPLYDTG	GLCE	541	O94923
MSPGSGVKSEYMKRY	CCSAP	1	Q6IQ19
LVGPSLKGYEVTDMM	CACNB2	286	Q08289
PESMAIYKSMDYGRT	NTN1	156	O95631
GTIITPDEYTGKIMM	GUF1	476	Q8N442
FTLTYTLMGEWKMGP	NPY2R	106	P49146
DSPGRYEIMNFKEMG	GRM5	461	P41594
METKGYHSLPEGLDM	NR3C2	1	P08235
YDGMLSDVQSMPKTG	MAGEA10	211	P43363
LPGGSYMAKLTVTLM	HLA-DRB5	6	Q30154
PMLDDEMLTYGSSKG	LRRC7	1001	Q96NW7
IYTTVMSAGSPDKYM	NAAA	336	Q02083
MTEEYKVPDGMVGFI	FUBP1	101	Q96AE4
SLLMTGPFMVAGEFK	LIMK2	76	P53671
MAVLTLYTDPMGSEK	HORMAD2	101	Q8N7B1
LYTDPMGSEKVTEMY	HORMAD2	106	Q8N7B1
EITFYMKGADVAMSP	ATP9B	651	O43861
TSELDMGKGPMYDVE	DCLK3	161	Q9C098
LEYMGMKGVSLPLGF	HK2	586	P52789
PLTAGMYTLTMKYGG	FLNB	1196	O75369
MYTLTMKYGGELVPH	FLNB	1201	O75369
LGIISTSKPMDYELM	FAT2	511	Q9NYQ8
KTLSIFMEYMPGGSI	MAP3K2	431	Q9Y2U5
YSGVISTTMGPKDHM	PINLYP	81	A6NC86
VTMTTLGYGDMVPKT	KCND2	366	Q9NZV8
TMTGVMGLEPSSYKT	MED12	1881	Q93074
ETSGLMLDVGPYMKA	LHPP	161	Q9H008
LPGLASAMKYLSEMG	EPHA10	751	Q5JZY3
DILLVGAPMYMGTEK	ITGA1	506	P56199
TGTEEYMKMDLGPGR	IRS1	936	P35568
MRSLSELLGPYGMKF	NCKAP1	836	Q9Y2A7
SYMVKGMAFSPDSTK	IFT172	66	Q9UG01
VTHLMGLFEPGDMKY	ALPG	281	P10696
IITYGKMPYSGMTGA	FRK	426	P42685
VGMEAATDEGMPKSY	IL6ST	891	P40189
TGAIPMGELSMYTLS	CACNG4	266	Q9UBN1
YMIVGDPMGGKTSAY	DNAH3	1706	Q8TD57
MSIKAYVSTLMGVPG	EIF3F	211	O00303
VMVEMSGPSKGYLSF	FRRS1	231	Q6ZNA5
MTPELMIKACSFYTG	FBXL13	1	Q8NEE6
EFIVMGGTFMALPEE	ELP3	166	Q9H9T3
AYGVKRFSPMTIDGM	ELAVL2	246	Q12926
MSLMYLISGPGVDEY	CDH26	86	Q8IXH8
TTMDYPSLGLMTEKL	ITGB3	311	P05106
SIPFYLSGKMMVGEI	TMEM30CP	91	A0ZSE6
MYISKMVPTSDKGRF	EEF2	396	P13639
SGMYLASGGDDKLIM	HIRA	81	P54198
SGYGMEMLTDKGLSE	GTF2IRD1	531	Q9UHL9
VPFGGKSMITFMDDL	DNAH2	2471	Q9P225
CTSPETVIKYMTDGM	DHX8	651	Q14562
EKTLTIFMEYMPGGS	MAP3K3	436	Q99759
GSYTLVLKAMLGMPS	OR11H1	231	Q8NG94
MGKLTTMPAGLIYAS	APOOL	6	Q6UXV4
MSSPYKGEGRGIAML	MROH2A	586	A6NES4
ELMSGFSVPKETRMY	NAV1	861	Q8NEY1
LPYSGSMMGGKDFVV	SUSD2	66	Q9UGT4
VGTYIEKMFMSELSG	NDUFS1	206	P28331
MTGMGEVDFLTFDPI	TAF1B	331	Q53T94
MDAPGYMSDGDVLSK	NAV2	881	Q8IVL1
PTKGYEEDVGRMTMI	ST6GALNAC3	111	Q8NDV1
VPYVYGALTGLMETM	OR5M8	146	Q8NGP6
AESYSLISMKGMGDP	AKAP3	401	O75969
TTMPLGLGMTVDYIF	ANGEL1	591	Q9UNK9
MVLTGRGKYSDPMEI	CHST11	136	Q9NPF2
MSEILPYSEDKMGRF	CAMK2N2	1	Q96S95
FYTPKELGGLGMLSM	PRPF8	1316	Q6P2Q9
MYVVSGLVAKEMAGP	SLC7A14	71	Q8TBB6
DMSSSLKSYDFPIGM	SLC23A1	536	Q9UHI7
MTLDGFMMYLLSPEG	PLCD3	311	Q8N3E9
GLQDPEGFLFKEMMT	WDR97	1316	A6NE52
YLPEGDFSIMTEMLK	WAPL	1146	Q7Z5K2
PGSMMVGIYGKIFAV	TAAR2	221	Q9P1P5
MYGPLDMVALTGEKV	PITPNM3	656	Q9BZ71
GYDSMGYEMSKPDLR	TOP3A	571	Q13472
GTMYPMSVYSGKVLL	SLC30A6	241	Q6NXT4
ISTMVHFYMGTKGPE	USP34	2466	Q70CQ2
MDDFLGVYSMPAGTK	TLE6	521	Q9H808
LPFYAGMDMGTKSIC	TAS2R4	251	Q9NYW5
TMTTVGYGDMKPITV	KCNA4	521	P22459
PTETIYVGEMKDGMF	MORN5	26	Q5VZ52
VVTMTTLGYGDMYPK	KCNC4	431	Q03721
SLEDTIYVMGGLMSK	KLHL35	486	Q6PF15
RFGKYLEMMFTPTGV	MYO3B	491	Q8WXR4
MTKSYSESGLMGEPQ	NEUROD1	1	Q13562