| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | ubiquitin-like ligase-substrate adaptor activity | 6.62e-10 | 82 | 25 | 6 | GO:1990756 | |
| GeneOntologyMolecularFunction | enzyme-substrate adaptor activity | 1.63e-09 | 95 | 25 | 6 | GO:0140767 | |
| GeneOntologyMolecularFunction | nuclear retinoic acid receptor binding | 6.70e-09 | 55 | 25 | 5 | GO:0042974 | |
| GeneOntologyMolecularFunction | nuclear receptor binding | 3.12e-06 | 187 | 25 | 5 | GO:0016922 | |
| GeneOntologyMolecularFunction | RNA polymerase II-specific DNA-binding transcription factor binding | 1.46e-04 | 417 | 25 | 5 | GO:0061629 | |
| GeneOntologyMolecularFunction | protein-macromolecule adaptor activity | 4.18e-04 | 1160 | 25 | 7 | GO:0030674 | |
| GeneOntologyMolecularFunction | DNA-binding transcription factor binding | 6.77e-04 | 582 | 25 | 5 | GO:0140297 | |
| GeneOntologyMolecularFunction | molecular adaptor activity | 1.06e-03 | 1356 | 25 | 7 | GO:0060090 | |
| GeneOntologyMolecularFunction | transcription factor binding | 2.13e-03 | 753 | 25 | 5 | GO:0008134 | |
| GeneOntologyBiologicalProcess | negative regulation of developmental process | LGMN PRAMEF25 PRAMEF4 PRAMEF9 PRAMEF26 PRAMEF27 LOXL2 PRAMEF11 PRAMEF15 | 1.07e-05 | 1220 | 26 | 9 | GO:0051093 |
| GeneOntologyBiologicalProcess | negative regulation of DNA-templated transcription | CREBRF PRAMEF25 PRAMEF4 PRAMEF9 PRAMEF26 PRAMEF27 LOXL2 PRAMEF11 PRAMEF15 | 3.22e-05 | 1399 | 26 | 9 | GO:0045892 |
| GeneOntologyBiologicalProcess | negative regulation of RNA biosynthetic process | CREBRF PRAMEF25 PRAMEF4 PRAMEF9 PRAMEF26 PRAMEF27 LOXL2 PRAMEF11 PRAMEF15 | 3.48e-05 | 1413 | 26 | 9 | GO:1902679 |
| GeneOntologyBiologicalProcess | negative regulation of apoptotic process | LGMN PRAMEF25 PRAMEF4 PRAMEF9 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF15 | 5.19e-05 | 1133 | 26 | 8 | GO:0043066 |
| GeneOntologyBiologicalProcess | negative regulation of programmed cell death | LGMN PRAMEF25 PRAMEF4 PRAMEF9 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF15 | 6.56e-05 | 1171 | 26 | 8 | GO:0043069 |
| GeneOntologyBiologicalProcess | positive regulation of cell population proliferation | LGMN PRAMEF25 PRAMEF4 PRAMEF9 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF15 | 7.36e-05 | 1190 | 26 | 8 | GO:0008284 |
| GeneOntologyBiologicalProcess | negative regulation of cell differentiation | PRAMEF25 PRAMEF4 PRAMEF9 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF15 | 7.82e-05 | 875 | 26 | 7 | GO:0045596 |
| GeneOntologyBiologicalProcess | blastocyst formation | 1.27e-04 | 78 | 26 | 3 | GO:0001825 | |
| GeneOntologyBiologicalProcess | stem cell population maintenance | 2.08e-04 | 237 | 26 | 4 | GO:0019827 | |
| GeneOntologyBiologicalProcess | maintenance of cell number | 2.26e-04 | 242 | 26 | 4 | GO:0098727 | |
| GeneOntologyBiologicalProcess | oocyte development | 2.57e-04 | 99 | 26 | 3 | GO:0048599 | |
| GeneOntologyBiologicalProcess | oocyte differentiation | 2.89e-04 | 103 | 26 | 3 | GO:0009994 | |
| GeneOntologyBiologicalProcess | somatic stem cell population maintenance | 3.32e-04 | 108 | 26 | 3 | GO:0035019 | |
| GeneOntologyBiologicalProcess | oogenesis | 9.71e-04 | 156 | 26 | 3 | GO:0048477 | |
| GeneOntologyBiologicalProcess | blastocyst development | 1.44e-03 | 179 | 26 | 3 | GO:0001824 | |
| GeneOntologyCellularComponent | Cul2-RING ubiquitin ligase complex | 2.06e-11 | 47 | 26 | 6 | GO:0031462 | |
| GeneOntologyCellularComponent | cullin-RING ubiquitin ligase complex | 5.58e-09 | 212 | 26 | 7 | GO:0031461 | |
| GeneOntologyCellularComponent | ubiquitin ligase complex | 1.81e-07 | 352 | 26 | 7 | GO:0000151 | |
| GeneOntologyCellularComponent | transferase complex | 1.31e-04 | 963 | 26 | 7 | GO:1990234 | |
| GeneOntologyCellularComponent | intracellular protein-containing complex | 1.39e-04 | 972 | 26 | 7 | GO:0140535 | |
| GeneOntologyCellularComponent | chromatin | 1.75e-03 | 1480 | 26 | 7 | GO:0000785 | |
| GeneOntologyCellularComponent | acrosomal vesicle | 2.07e-03 | 206 | 26 | 3 | GO:0001669 | |
| MousePheno | abnormal spermatogonia proliferation | 3.87e-09 | 47 | 19 | 5 | MP:0002685 | |
| MousePheno | increased male germ cell apoptosis | 4.27e-06 | 189 | 19 | 5 | MP:0014052 | |
| MousePheno | abnormal male germ cell apoptosis | 1.26e-05 | 236 | 19 | 5 | MP:0008280 | |
| MousePheno | azoospermia | 1.48e-05 | 244 | 19 | 5 | MP:0005159 | |
| MousePheno | abnormal male germ cell physiology | 1.48e-05 | 244 | 19 | 5 | MP:0020362 | |
| MousePheno | abnormal vitreous body morphology | 1.56e-05 | 429 | 19 | 6 | MP:0002699 | |
| MousePheno | absent gametes | 1.87e-05 | 256 | 19 | 5 | MP:0001117 | |
| MousePheno | abnormal jejunum morphology | 2.20e-05 | 41 | 19 | 3 | MP:0004002 | |
| MousePheno | abnormal germ cell physiology | 2.29e-05 | 267 | 19 | 5 | MP:0020363 | |
| MousePheno | abnormal duodenum morphology | 8.42e-05 | 64 | 19 | 3 | MP:0003271 | |
| MousePheno | decreased testis weight | 1.08e-04 | 370 | 19 | 5 | MP:0004852 | |
| MousePheno | abnormal testis weight | 1.40e-04 | 391 | 19 | 5 | MP:0004850 | |
| MousePheno | small kidney | 2.07e-04 | 425 | 19 | 5 | MP:0002989 | |
| MousePheno | abnormal cecum morphology | 3.07e-04 | 99 | 19 | 3 | MP:0000494 | |
| MousePheno | cataract | 4.28e-04 | 497 | 19 | 5 | MP:0001304 | |
| MousePheno | enlarged urinary bladder | 4.90e-04 | 116 | 19 | 3 | MP:0011874 | |
| MousePheno | increased circulating amylase level | 5.28e-04 | 119 | 19 | 3 | MP:0008806 | |
| MousePheno | abnormal auditory brainstem response | 8.39e-04 | 576 | 19 | 5 | MP:0004738 | |
| MousePheno | increased kidney weight | 9.38e-04 | 145 | 19 | 3 | MP:0003917 | |
| MousePheno | abnormal hearing electrophysiology | 9.64e-04 | 594 | 19 | 5 | MP:0006335 | |
| MousePheno | abnormal circulating amylase level | 1.16e-03 | 156 | 19 | 3 | MP:0008804 | |
| MousePheno | abnormal sperm number | 1.20e-03 | 624 | 19 | 5 | MP:0002673 | |
| MousePheno | decreased male germ cell number | 1.35e-03 | 640 | 19 | 5 | MP:0004901 | |
| MousePheno | abnormal hearing physiology | 1.38e-03 | 643 | 19 | 5 | MP:0001963 | |
| MousePheno | increased apoptosis | 1.66e-03 | 1008 | 19 | 6 | MP:0006042 | |
| MousePheno | increased cell death | 1.76e-03 | 1019 | 19 | 6 | MP:0012556 | |
| MousePheno | abnormal ear physiology | 1.81e-03 | 684 | 19 | 5 | MP:0003878 | |
| MousePheno | decreased germ cell number | 1.85e-03 | 687 | 19 | 5 | MP:0002209 | |
| MousePheno | abnormal small intestine morphology | 1.95e-03 | 187 | 19 | 3 | MP:0000496 | |
| MousePheno | abnormal lens morphology | 1.99e-03 | 699 | 19 | 5 | MP:0001303 | |
| MousePheno | increased circulating alanine transaminase level | 2.03e-03 | 412 | 19 | 4 | MP:0002941 | |
| MousePheno | abnormal kidney size | 2.19e-03 | 714 | 19 | 5 | MP:0002706 | |
| MousePheno | abnormal kidney weight | 2.64e-03 | 208 | 19 | 3 | MP:0002707 | |
| MousePheno | abnormal gametes | 3.31e-03 | 785 | 19 | 5 | MP:0001124 | |
| Domain | PRAME_family | 5.53e-09 | 19 | 22 | 4 | IPR026271 | |
| Domain | BBOX | 7.07e-05 | 69 | 22 | 3 | SM00336 | |
| Domain | Butyrophylin | 7.38e-05 | 70 | 22 | 3 | IPR003879 | |
| Domain | - | 7.70e-05 | 71 | 22 | 3 | 4.10.45.10 | |
| Domain | ZF_BBOX | 1.10e-04 | 80 | 22 | 3 | PS50119 | |
| Domain | ConA-like_dom | 1.14e-04 | 219 | 22 | 4 | IPR013320 | |
| Domain | Znf_B-box | 1.14e-04 | 81 | 22 | 3 | IPR000315 | |
| Domain | SPRY | 1.77e-04 | 94 | 22 | 3 | PF00622 | |
| Domain | SPRY_dom | 1.77e-04 | 94 | 22 | 3 | IPR003877 | |
| Domain | B30.2/SPRY | 1.83e-04 | 95 | 22 | 3 | IPR001870 | |
| Domain | B302_SPRY | 1.83e-04 | 95 | 22 | 3 | PS50188 | |
| Domain | - | 4.90e-04 | 321 | 22 | 4 | 3.80.10.10 | |
| Domain | L_dom-like | 5.32e-04 | 328 | 22 | 4 | IPR032675 | |
| Domain | Znf_RING_CS | 8.90e-04 | 163 | 22 | 3 | IPR017907 | |
| Domain | ZF_RING_1 | 4.63e-03 | 291 | 22 | 3 | PS00518 | |
| Domain | SPRY | 4.66e-03 | 87 | 22 | 2 | SM00449 | |
| Domain | ZF_RING_2 | 4.95e-03 | 298 | 22 | 3 | PS50089 | |
| Domain | RING | 5.28e-03 | 305 | 22 | 3 | SM00184 | |
| Domain | Znf_RING | 6.34e-03 | 326 | 22 | 3 | IPR001841 | |
| Domain | - | 1.51e-02 | 449 | 22 | 3 | 3.30.40.10 | |
| Domain | Znf_RING/FYVE/PHD | 1.60e-02 | 459 | 22 | 3 | IPR013083 | |
| Pubmed | 4.05e-12 | 22 | 26 | 5 | 31729367 | ||
| Pubmed | 8.16e-12 | 25 | 26 | 5 | 37451217 | ||
| Pubmed | 1.51e-11 | 28 | 26 | 5 | 25089626 | ||
| Pubmed | 4.96e-11 | 35 | 26 | 5 | 19389355 | ||
| Pubmed | 1.18e-09 | 20 | 26 | 4 | 26694250 | ||
| Pubmed | 1.68e-07 | 15 | 26 | 3 | 19703589 | ||
| Pubmed | Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse. | 2.50e-07 | 17 | 26 | 3 | 23565261 | |
| Pubmed | 2.50e-07 | 17 | 26 | 3 | 37781892 | ||
| Pubmed | Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes. | 3.00e-07 | 18 | 26 | 3 | 29731491 | |
| Pubmed | 3.00e-07 | 18 | 26 | 3 | 23894331 | ||
| Pubmed | Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos. | 3.00e-07 | 18 | 26 | 3 | 12890732 | |
| Pubmed | Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation. | 3.00e-07 | 18 | 26 | 3 | 39181896 | |
| Pubmed | 3.00e-07 | 18 | 26 | 3 | 14675769 | ||
| Pubmed | Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways. | 3.57e-07 | 19 | 26 | 3 | 28604677 | |
| Pubmed | Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells. | 4.19e-07 | 20 | 26 | 3 | 21425410 | |
| Pubmed | 4.19e-07 | 20 | 26 | 3 | 16580637 | ||
| Pubmed | 6.50e-07 | 23 | 26 | 3 | 19480014 | ||
| Pubmed | Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei. | 8.44e-07 | 25 | 26 | 3 | 12620990 | |
| Pubmed | Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3. | 9.53e-07 | 26 | 26 | 3 | 18500982 | |
| Pubmed | Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice. | 1.49e-06 | 30 | 26 | 3 | 38786026 | |
| Pubmed | LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance. | 1.81e-06 | 32 | 26 | 3 | 37889087 | |
| Pubmed | 5.51e-06 | 46 | 26 | 3 | 17287250 | ||
| Pubmed | DUX is a non-essential synchronizer of zygotic genome activation. | 7.10e-06 | 50 | 26 | 3 | 31806660 | |
| Pubmed | Lineage-specific biology revealed by a finished genome assembly of the mouse. | 9.48e-06 | 55 | 26 | 3 | 19468303 | |
| Pubmed | 1.10e-05 | 1084 | 26 | 7 | 11544199 | ||
| Pubmed | 1.11e-05 | 58 | 26 | 3 | 31598710 | ||
| Pubmed | 1.17e-05 | 59 | 26 | 3 | 11279525 | ||
| Pubmed | The DNA sequence and biological annotation of human chromosome 1. | 9.26e-05 | 1031 | 26 | 6 | 16710414 | |
| Pubmed | 9.63e-05 | 326 | 26 | 4 | 17015433 | ||
| Pubmed | 1.22e-04 | 347 | 26 | 4 | 16033648 | ||
| Pubmed | Transcriptome analysis of mouse stem cells and early embryos. | 1.46e-04 | 363 | 26 | 4 | 14691545 | |
| Pubmed | ERp57 is essential for efficient folding of glycoproteins sharing common structural domains. | 1.60e-04 | 25 | 26 | 2 | 17170699 | |
| Pubmed | 2.47e-04 | 164 | 26 | 3 | 32409323 | ||
| Interaction | PRAMEF4 interactions | 3.74e-06 | 3 | 23 | 2 | int:PRAMEF4 | |
| Interaction | PRAMEF5 interactions | 3.47e-05 | 8 | 23 | 2 | int:PRAMEF5 | |
| Interaction | PRAMEF9 interactions | 9.64e-05 | 13 | 23 | 2 | int:PRAMEF9 | |
| Interaction | C1QB interactions | 1.63e-04 | 94 | 23 | 3 | int:C1QB | |
| Cytoband | 1p36.21 | 1.18e-12 | 63 | 26 | 6 | 1p36.21 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr1p36 | CCDC27 PRAMEF25 PRAMEF4 PRAMEF9 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF15 | 2.78e-09 | 681 | 26 | 8 | chr1p36 |
| Cytoband | 2q11.1 | 1.16e-04 | 28 | 26 | 2 | 2q11.1 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr2q11 | 3.40e-03 | 153 | 26 | 2 | chr2q11 | |
| GeneFamily | PRAME family | PRAMEF25 PRAMEF4 PRAMEF9 PRAMEF26 PRAMEF27 PRAMEF11 PRAMEF15 | 2.12e-16 | 24 | 20 | 7 | 686 |
| GeneFamily | Ring finger proteins|Tripartite motif containing|ARF GTPase family | 1.50e-04 | 95 | 20 | 3 | 59 | |
| GeneFamily | Ring finger proteins | 3.28e-03 | 275 | 20 | 3 | 58 | |
| Coexpression | KOHOUTEK_CCNT2_TARGETS | 1.26e-08 | 81 | 25 | 5 | MM938 | |
| Coexpression | INGRAM_SHH_TARGETS_UP | 3.38e-07 | 156 | 25 | 5 | MM550 | |
| Coexpression | YAMAZAKI_TCEB3_TARGETS_DN | 2.39e-06 | 232 | 25 | 5 | MM1019 | |
| Coexpression | KINNEY_DNMT1_METHYLATION_TARGETS | 4.50e-06 | 34 | 25 | 3 | MM955 | |
| Coexpression | MEISSNER_BRAIN_HCP_WITH_H3_UNMETHYLATED | 2.17e-05 | 57 | 25 | 3 | MM1262 | |
| Coexpression | SANSOM_APC_TARGETS | 8.07e-05 | 245 | 25 | 4 | MM735 | |
| Coexpression | MIKKELSEN_ES_ICP_WITH_H3K4ME3 | 8.97e-05 | 807 | 25 | 6 | MM855 | |
| Coexpression | DESCARTES_ORGANOGENESIS_SCHWANN_CELL_PRECURSOR | 1.10e-04 | 98 | 25 | 3 | MM3656 | |
| Coexpression | HUANG_GATA2_TARGETS_DN | 1.10e-04 | 98 | 25 | 3 | MM942 | |
| Coexpression | MORI_SMALL_PRE_BII_LYMPHOCYTE_UP | 1.10e-04 | 98 | 25 | 3 | MM592 | |
| Coexpression | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS | 1.36e-04 | 871 | 25 | 6 | MM1005 | |
| ToppCell | TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Monophasic_Synovial_Sarcoma-5|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9 | 2.47e-07 | 93 | 26 | 4 | 3e05ea0f8f4a7cdb78a596f47d563dc3c94d4d8e | |
| Disease | childhood trauma measurement, alcohol consumption measurement | 8.52e-04 | 71 | 18 | 2 | EFO_0007878, EFO_0007979 | |
| Disease | erosive tooth wear measurement | 1.36e-03 | 90 | 18 | 2 | EFO_0009331 | |
| Disease | urate measurement, bone density | 5.93e-03 | 619 | 18 | 3 | EFO_0003923, EFO_0004531 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| VHWARFNDIMCWSTD | 571 | Q9UKF5 | |
| SNWEQWDTYCEDLTK | 86 | Q8IUR6 | |
| IHWWENVYGFDMTCI | 236 | Q9NR22 | |
| EELQHWWQMQEESAA | 311 | Q2M243 | |
| TVDWRDFMCNTWHLE | 4916 | Q2LD37 | |
| WDMYRHDIDCQWVDI | 686 | Q9Y4K0 | |
| SKVWSDMAVWNEDYC | 246 | Q5T2Q4 | |
| LDSSDDWQTYHNEMC | 171 | P26006 | |
| DLQDVCENFWMVWSE | 106 | P0DUQ1 | |
| AENDFWMYDHSTNRW | 356 | Q8NFY9 | |
| DFWRMVWQEHCSSIV | 971 | Q92729 | |
| WMECVWHSTGIYQCQ | 51 | O95500 | |
| CMNETEWTIYQDWHD | 146 | P27707 | |
| LQDVCENFWMVWSEA | 11 | H0Y7S4 | |
| LWEQSGHWEHYQEDM | 361 | Q9BW92 | |
| KHYWELDVDNSCDWA | 336 | Q96BQ3 | |
| DLQDVCENFWMVWSE | 106 | A6NGN4 | |
| DLQDVCENFWMVWSE | 106 | A3QJZ7 | |
| HWDYLCEEMQWLSAD | 136 | Q6ZRS2 | |
| DLQDVCENFWMVWSE | 106 | O60810 | |
| HYWEVDVKDSCNWVI | 341 | I1YAP6 | |
| DLQDVCENFWMVWSE | 106 | P0DUQ2 | |
| DLQDVCENFWMVWSE | 106 | O60813 | |
| DFAHSWNESWVNRME | 181 | Q13530 | |
| KHYWELDVDNSCDWA | 336 | A6NCK2 | |
| MDCQENEYWDQWGRC | 1 | Q9HAV5 | |
| DWYSVNWMEDSDVED | 231 | Q99538 |