Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	NUP98 RGPD2	1.84e-04	10	43	2	GO:0044614
GeneOntologyCellularComponent	nuclear pore nuclear basket	NUP98 RGPD2	6.19e-04	18	43	2	GO:0044615
GeneOntologyCellularComponent	nuclear inclusion body	NUP98 RGPD2	7.67e-04	20	43	2	GO:0042405
GeneOntologyCellularComponent	SUMO ligase complex	RGPD2 NSMCE4A	8.47e-04	21	43	2	GO:0106068
MousePheno	enlarged stomach	ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	1.44e-06	33	36	4	MP:0003883
Domain	Spectrin_repeat	KALRN DSP SYNE1	3.98e-05	29	43	3	IPR002017
Domain	Spectrin/alpha-actinin	KALRN DSP SYNE1	5.38e-05	32	43	3	IPR018159
Domain	SPEC	KALRN DSP SYNE1	5.38e-05	32	43	3	SM00150
Domain	Spectrin	KALRN SYNE1	1.27e-03	23	43	2	PF00435
Domain	Ank_2	ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD20A1	1.48e-03	215	43	4	PF12796
Domain	Ank	ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD20A1	1.84e-03	228	43	4	PF00023
Domain	RA	RADIL RAPGEF6	2.31e-03	31	43	2	SM00314
Domain	TGF-beta-rel	GDF5 BMP15	2.46e-03	32	43	2	IPR015615
Domain	TGFb_CS	GDF5 BMP15	2.46e-03	32	43	2	IPR017948
Domain	-	ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD20A1	2.49e-03	248	43	4	1.25.40.20
Domain	ANK	ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD20A1	2.60e-03	251	43	4	SM00248
Domain	ANK_REPEAT	ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD20A1	2.68e-03	253	43	4	PS50088
Domain	Ankyrin_rpt-contain_dom	ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD20A1	2.72e-03	254	43	4	IPR020683
Domain	ANK_REP_REGION	ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD20A1	2.72e-03	254	43	4	PS50297
Domain	Ankyrin_rpt	ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD20A1	3.04e-03	262	43	4	IPR002110
Domain	RA	RADIL RAPGEF6	3.10e-03	36	43	2	PF00788
Domain	TGFB	GDF5 BMP15	3.28e-03	37	43	2	SM00204
Domain	TGF-b_C	GDF5 BMP15	3.28e-03	37	43	2	IPR001839
Domain	TGF_BETA_2	GDF5 BMP15	3.28e-03	37	43	2	PS51362
Domain	RA	RADIL RAPGEF6	3.28e-03	37	43	2	PS50200
Domain	TGF_beta	GDF5 BMP15	3.28e-03	37	43	2	PF00019
Domain	TGF_BETA_1	GDF5 BMP15	3.28e-03	37	43	2	PS00250
Domain	RA_dom	RADIL RAPGEF6	3.82e-03	40	43	2	IPR000159
Domain	PDZ	INTU RADIL RAPGEF6	4.77e-03	148	43	3	SM00228
Domain	-	INTU RADIL RAPGEF6	4.95e-03	150	43	3	2.30.42.10
Domain	PDZ	INTU RADIL RAPGEF6	5.05e-03	151	43	3	PS50106
Domain	PDZ	INTU RADIL RAPGEF6	5.14e-03	152	43	3	IPR001478
Pathway	REACTOME_MITOTIC_PROMETAPHASE	NUP98 RGPD2 CLASP1 CSNK1D CSNK1E	7.21e-05	202	31	5	MM15362
Pathway	PID_HEDGEHOG_GLI_PATHWAY	SIN3A CSNK1D CSNK1E	1.56e-04	48	31	3	M219
Pathway	REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS	NUP98 CPSF1 RGPD2	1.76e-04	50	31	3	MM14610
Pathway	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS	OCLN DSP	2.08e-04	10	31	2	MM14956
Pathway	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS	OCLN DSP	2.54e-04	11	31	2	M9990
Pathway	KEGG_CIRCADIAN_RHYTHM_MAMMAL	CSNK1D CSNK1E	3.60e-04	13	31	2	M18009
Pathway	REACTOME_SUMOYLATION	NUP98 RGPD2 SIN3A NSMCE4A	4.87e-04	169	31	4	MM14919
Pathway	REACTOME_AURKA_ACTIVATION_BY_TPX2	CLASP1 CSNK1D CSNK1E	4.97e-04	71	31	3	MM15495
Pathway	REACTOME_AURKA_ACTIVATION_BY_TPX2	CLASP1 CSNK1D CSNK1E	5.18e-04	72	31	3	M27749
Pathway	PID_BETA_CATENIN_DEG_PATHWAY	CSNK1D CSNK1E	7.01e-04	18	31	2	M31
Pathway	REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES	CLASP1 CSNK1D CSNK1E	7.32e-04	81	31	3	M748
Pathway	REACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS	NUP98 RGPD2 NSMCE4A	8.13e-04	84	31	3	MM14929
Pathway	REACTOME_REGULATION_OF_PLK1_ACTIVITY_AT_G2_M_TRANSITION	CLASP1 CSNK1D CSNK1E	8.42e-04	85	31	3	MM14906
Pathway	REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM	NUP98 CPSF1 RGPD2	8.71e-04	86	31	3	MM15413
Pathway	REACTOME_REGULATION_OF_PLK1_ACTIVITY_AT_G2_M_TRANSITION	CLASP1 CSNK1D CSNK1E	9.01e-04	87	31	3	M27194
Pathway	REACTOME_MITOTIC_PROMETAPHASE	NUP98 CLASP1 CSNK1D CSNK1E	9.86e-04	204	31	4	M4217
Pathway	REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES	CLASP1 CSNK1D CSNK1E	9.94e-04	90	31	3	MM14979
Pathway	REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES	CLASP1 CSNK1D CSNK1E	1.16e-03	95	31	3	M6729
Pathway	REACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE	CLASP1 CSNK1D CSNK1E	1.20e-03	96	31	3	MM15207
Pathway	REACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE	CLASP1 CSNK1D CSNK1E	1.23e-03	97	31	3	M27478
Pathway	REACTOME_AMPLIFICATION_OF_SIGNAL_FROM_THE_KINETOCHORES	NUP98 RGPD2 CLASP1	1.35e-03	100	31	3	MM14561
Pathway	REACTOME_M_PHASE	NUP98 RGPD2 CLASP1 CSNK1D CSNK1E	1.43e-03	387	31	5	MM15364
Pathway	REACTOME_METABOLISM_OF_RNA	NUP98 CPSF1 RGPD2 CSNK1D CSNK1E DHX8	1.90e-03	612	31	6	MM15547
Pathway	REACTOME_MITOTIC_SPINDLE_CHECKPOINT	NUP98 RGPD2 CLASP1	2.11e-03	117	31	3	MM15387
Pathway	WP_MAMMARY_GLAND_DEVELOPMENT_PREGNANCY_AND_LACTATION_STAGE_3_OF_4	ELF5 TNFSF11	2.37e-03	33	31	2	M39455
Pathway	REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION	NUP98 RGPD2 CLASP1	2.79e-03	129	31	3	MM14894
Pathway	WP_MELATONIN_METABOLISM_AND_EFFECTS	CSNK1D CSNK1E	2.97e-03	37	31	2	M39418
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	GDF5 ITGB5	2.97e-03	37	31	2	M27134
Pathway	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS	OCLN DSP	2.97e-03	37	31	2	MM14488
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA	NUP98 CPSF1 RGPD2 DHX8	3.02e-03	277	31	4	MM15414
Pubmed	Expression of testicular germ cell genes identified by differential display analysis.	ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	2.04e-10	8	47	4	12634303
Pubmed	A molecular mechanism for circadian clock negative feedback.	SIN3A CSNK1D CSNK1E	6.55e-07	13	47	3	21680841
Pubmed	Effects of altered expression and activity levels of CK1δ and ɛ on tumor growth and survival of colorectal cancer patients.	CSNK1D CSNK1E	1.79e-06	2	47	2	25404202
Pubmed	Casein kinase I delta/epsilon phosphorylates topoisomerase IIalpha at serine-1106 and modulates DNA cleavage activity.	CSNK1D CSNK1E	1.79e-06	2	47	2	19043076
Pubmed	CK1δ and CK1ε are components of human 40S subunit precursors required for cytoplasmic 40S maturation.	CSNK1D CSNK1E	1.79e-06	2	47	2	24424021
Pubmed	Regulation of casein kinase I epsilon and casein kinase I delta by an in vivo futile phosphorylation cycle.	CSNK1D CSNK1E	1.79e-06	2	47	2	9632646
Pubmed	An evaluation of polymorphisms in casein kinase 1 delta and epsilon genes in major psychiatric disorders.	CSNK1D CSNK1E	1.79e-06	2	47	2	22981886
Pubmed	Targeting of the circadian clock via CK1δ/ε to improve glucose homeostasis in obesity.	CSNK1D CSNK1E	5.36e-06	3	47	2	27439882
Pubmed	Gene expression levels of Casein kinase 1 (CK1) isoforms are correlated to adiponectin levels in adipose tissue of morbid obese patients and site-specific phosphorylation mediated by CK1 influences multimerization of adiponectin.	CSNK1D CSNK1E	5.36e-06	3	47	2	25724478
Pubmed	A comparative study of structural and conformational properties of casein kinase-1 isoforms: insights from molecular dynamics and principal component analysis.	CSNK1D CSNK1E	5.36e-06	3	47	2	25665722
Pubmed	CKIepsilon/delta-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock.	CSNK1D CSNK1E	5.36e-06	3	47	2	19805222
Pubmed	CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1.	CSNK1D CSNK1E	5.36e-06	3	47	2	32321936
Pubmed	Centrosomal anchoring of the protein kinase CK1delta mediated by attachment to the large, coiled-coil scaffolding protein CG-NAP/AKAP450.	CSNK1D CSNK1E	5.36e-06	3	47	2	12270714
Pubmed	Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.	CSNK1D CSNK1E	5.36e-06	3	47	2	28963394
Pubmed	Human Rad17 C-terminal tail is phosphorylated by concerted action of CK1δ/ε and CK2 to promote interaction with the 9-1-1 complex.	CSNK1D CSNK1E	5.36e-06	3	47	2	31353086
Pubmed	Sequence analysis of the cDNA for the human casein kinase I delta (CSNK1D) gene and its chromosomal localization.	CSNK1D CSNK1E	5.36e-06	3	47	2	8786104
Pubmed	Casein kinase 1 proteomics reveal prohibitin 2 function in molecular clock.	CSNK1D CSNK1E	5.36e-06	3	47	2	22384121
Pubmed	Paracrine-rescued lobulogenesis in chimeric outgrowths comprising progesterone-receptor-null mammary epithelium and redirected wild-type testicular cells.	ELF5 TNFSF11	5.36e-06	3	47	2	24190884
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	NUP98 CPSF1 SIN3A RAPGEF6 CLASP1 DSP CSNK1E WDR44	8.47e-06	774	47	8	15302935
Pubmed	CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch.	CSNK1D CSNK1E	1.07e-05	4	47	2	29784789
Pubmed	Involvement of casein kinase 1 epsilon/delta (Csnk1e/d) in the pathogenesis of familial Parkinson's disease caused by CHCHD2.	CSNK1D CSNK1E	1.07e-05	4	47	2	37578019
Pubmed	Casein kinase 1 delta (CK1delta) regulates period length of the mouse suprachiasmatic circadian clock in vitro.	CSNK1D CSNK1E	1.07e-05	4	47	2	20421981
Pubmed	Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowth.	CSNK1D CSNK1E	1.07e-05	4	47	2	21422228
Pubmed	Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells.	ELF5 TNFSF11	1.07e-05	4	47	2	23462470
Pubmed	Involvement of casein kinase Iepsilon in cytokine-induced granulocytic differentiation.	CSNK1D CSNK1E	1.07e-05	4	47	2	15070676
Pubmed	The DNA-binding activity of mouse DNA methyltransferase 1 is regulated by phosphorylation with casein kinase 1delta/epsilon.	CSNK1D CSNK1E	1.07e-05	4	47	2	20192920
Pubmed	Rankl Impairs Lactogenic Differentiation Through Inhibition of the Prolactin/Stat5 Pathway at Midgestation.	ELF5 TNFSF11	1.07e-05	4	47	2	26695351
Pubmed	Therapeutic Targeting of Casein Kinase 1δ/ε in an Alzheimer's Disease Mouse Model.	CSNK1D CSNK1E	1.07e-05	4	47	2	31334659
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-10 ERVK-24	1.07e-05	4	47	2	10469592
Pubmed	p53 is phosphorylated in vitro and in vivo by the delta and epsilon isoforms of casein kinase 1 and enhances the level of casein kinase 1 delta in response to topoisomerase-directed drugs.	CSNK1D CSNK1E	1.07e-05	4	47	2	9349507
Pubmed	Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family.	CSNK1D CSNK1E	1.07e-05	4	47	2	7797465
Pubmed	Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon.	CSNK1D CSNK1E	1.78e-05	5	47	2	10848614
Pubmed	Phosphorylation of human enhancer filamentation 1 (HEF1) stimulates interaction with Polo-like kinase 1 leading to HEF1 localization to focal adhesions.	CSNK1D CSNK1E	1.78e-05	5	47	2	29191835
Pubmed	Desynchrony between brain and peripheral clocks caused by CK1δ/ε disruption in GABA neurons does not lead to adverse metabolic outcomes.	CSNK1D CSNK1E	1.78e-05	5	47	2	29463694
Pubmed	Control of intracellular dynamics of mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in cultured cells.	CSNK1D CSNK1E	1.78e-05	5	47	2	11865049
Pubmed	Casein kinase 1 delta regulates the pace of the mammalian circadian clock.	CSNK1D CSNK1E	1.78e-05	5	47	2	19414593
Pubmed	Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin.	CSNK1D CSNK1E	1.78e-05	5	47	2	17027228
Pubmed	The CK1δ/ε-AES axis regulates tumorigenesis and metastasis in colorectal cancer.	CSNK1D CSNK1E	1.78e-05	5	47	2	33754069
Pubmed	Essential roles of CKIdelta and CKIepsilon in the mammalian circadian clock.	CSNK1D CSNK1E	1.78e-05	5	47	2	19948962
Pubmed	TSG-6 regulates bone remodeling through inhibition of osteoblastogenesis and osteoclast activation.	GDF5 TNFSF11	1.78e-05	5	47	2	18586671
Pubmed	Identification of a novel Wnt5a-CK1ɛ-Dvl2-Plk1-mediated primary cilia disassembly pathway.	CSNK1D CSNK1E	2.67e-05	6	47	2	22609948
Pubmed	Association of genetic variation in genes implicated in the beta-catenin destruction complex with risk of breast cancer.	CSNK1D CSNK1E	2.67e-05	6	47	2	18708403
Pubmed	Osteoprotegerin Disruption Attenuates HySu-Induced Pulmonary Hypertension Through Integrin αvβ3/FAK/AKT Pathway Suppression.	TNFSF11 ITGB5	2.67e-05	6	47	2	28077433
Pubmed	Epiplakin attenuates experimental mouse liver injury by chaperoning keratin reorganization.	OCLN DSP	2.67e-05	6	47	2	25617501
Pubmed	Casein kinase I epsilon associates with and phosphorylates the tight junction protein occludin.	OCLN CSNK1E	2.67e-05	6	47	2	16616143
Pubmed	A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP).	CSNK1D CSNK1E	2.67e-05	6	47	2	20048001
Pubmed	Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2.	CSNK1D CSNK1E	2.67e-05	6	47	2	17962809
Pubmed	Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex.	CSNK1D CSNK1E	2.67e-05	6	47	2	11818547
Pubmed	Physiological role for casein kinase 1 in glutamatergic synaptic transmission.	CSNK1D CSNK1E	2.67e-05	6	47	2	16014721
Pubmed	High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase.	CSNK1D CSNK1E	2.67e-05	6	47	2	21179498
Pubmed	Genetic evidence that SOST inhibits WNT signaling in the limb.	GDF5 FBXW2 ITGB5	3.15e-05	45	47	3	20359476
Pubmed	Modeling of a human circadian mutation yields insights into clock regulation by PER2.	CSNK1D CSNK1E	3.74e-05	7	47	2	17218255
Pubmed	Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway.	CSNK1D CSNK1E	3.74e-05	7	47	2	12000790
Pubmed	SPOP-mediated ubiquitination and degradation of PDK1 suppresses AKT kinase activity and oncogenic functions.	CSNK1D CSNK1E	3.74e-05	7	47	2	34353330
Pubmed	SCFFBW7-mediated degradation of Brg1 suppresses gastric cancer metastasis.	CSNK1D CSNK1E	3.74e-05	7	47	2	30177679
Pubmed	Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism.	CSNK1D CSNK1E	4.98e-05	8	47	2	17244647
Pubmed	Casein kinase 1 delta (CK1delta) interacts with the SNARE associated protein snapin.	CSNK1D CSNK1E	4.98e-05	8	47	2	17101137
Pubmed	The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1.	CSNK1D CSNK1E	4.98e-05	8	47	2	21930935
Pubmed	Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1.	CSNK1D CSNK1E	4.98e-05	8	47	2	16618118
Pubmed	The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion.	CLASP1 CSNK1D CSNK1E	6.10e-05	56	47	3	11076968
Pubmed	The cell adhesion molecule nectin-1 is critical for normal enamel formation in mice.	OCLN DSP	6.40e-05	9	47	2	18703497
Pubmed	SDCBP promotes pancreatic cancer progression by preventing YAP1 from β-TrCP-mediated proteasomal degradation.	CSNK1D CSNK1E	6.40e-05	9	47	2	36828627
Pubmed	Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase.	CSNK1D CSNK1E	6.40e-05	9	47	2	20708156
Pubmed	The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation.	CLASP1 CSNK1D CSNK1E	6.43e-05	57	47	3	16462731
Pubmed	Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation.	CLASP1 CSNK1D CSNK1E	6.77e-05	58	47	3	12852856
Pubmed	Apocrine glands are bystanders in hidradenitis suppurativa and their involvement is gender specific.	ELF5 OCLN SYNE1	7.13e-05	59	47	3	32031713
Pubmed	Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function.	CLASP1 CSNK1D CSNK1E	7.88e-05	61	47	3	7790358
Pubmed	Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7.	CSNK1D CSNK1E	7.99e-05	10	47	2	25500533
Pubmed	USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification.	RAPGEF6 CSNK1D CSNK1E	8.27e-05	62	47	3	31340145
Pubmed	Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex.	CLASP1 CSNK1D CSNK1E	9.97e-05	66	47	3	12221128
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	FBXL16 PLCH1 CLASP1 KALRN NT5DC3 DSP CSNK1D SYNE1 CKMT1A	1.09e-04	1431	47	9	37142655
Pubmed	Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.	NUP98 RGPD2	1.38e-04	13	47	2	31427429
Pubmed	Clock genes may influence bipolar disorder susceptibility and dysfunctional circadian rhythm.	CSNK1D CSNK1E	1.38e-04	13	47	2	18228528
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RADIL RAPGEF6 PLCH1 CLASP1 DSP CSNK1D CSNK1E	1.48e-04	861	47	7	36931259
Pubmed	MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis.	OCLN DSP	1.61e-04	14	47	2	14627958
Pubmed	TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.	NUP98 NXT2	1.61e-04	14	47	2	11073998
Pubmed	Association of CPI-17 with protein kinase C and casein kinase I.	CSNK1D CSNK1E	1.86e-04	15	47	2	15003508
Pubmed	USP7 Is a Tumor-Specific WNT Activator for APC-Mutated Colorectal Cancer by Mediating β-Catenin Deubiquitination.	CSNK1D CSNK1E	2.12e-04	16	47	2	29045831
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-10 ERVK-24	2.70e-04	18	47	2	18664271
Pubmed	Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier.	OCLN DSP	3.01e-04	19	47	2	18166659
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	RADIL RAPGEF6 FBXL16 CLASP1 CSNK1E	3.34e-04	446	47	5	24255178
Pubmed	Centrosome-related genes, genetic variation, and risk of breast cancer.	CLASP1 CSNK1D CSNK1E	3.62e-04	102	47	3	20508983
Pubmed	Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1.	SETD1A SIN3A	3.69e-04	21	47	2	12670868
Pubmed	Identification of cellular proteins required for replication of human immunodeficiency virus type 1.	KALRN DHX8	3.69e-04	21	47	2	22404213
Pubmed	Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia.	CSNK1D CSNK1E	3.69e-04	21	47	2	19839995
Pubmed	Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene.	CSNK1D CSNK1E	4.06e-04	22	47	2	22305495
Pubmed	New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity.	OCLN DSP	4.44e-04	23	47	2	18809908
Pubmed	Keratins regulate protein biosynthesis through localization of GLUT1 and -3 upstream of AMP kinase and Raptor.	OCLN DSP	4.44e-04	23	47	2	19841136
Pubmed	Keratin 1 maintains skin integrity and participates in an inflammatory network in skin through interleukin-18.	OCLN DSP	5.26e-04	25	47	2	23132931
Pubmed	Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.	OCLN DSP	5.26e-04	25	47	2	31410202
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	SIN3A ZBTB11 CLASP1 CSNK1E DHX8 NSMCE4A	5.31e-04	759	47	6	35915203
Pubmed	Epidermal development requires ninein for spindle orientation and cortical microtubule organization.	OCLN DSP	5.69e-04	26	47	2	30923192
Pubmed	Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway.	RAPGEF6 CSNK1E	5.69e-04	26	47	2	28720576
Pubmed	Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.	GDF5 DSP LTN1	5.81e-04	120	47	3	21697133
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	NUP98 RGPD2 INTU PLCH1 ZBTB11 DSP SYNE1 NSMCE4A	6.37e-04	1442	47	8	35575683
Pubmed	Loss of LKB1 leads to impaired epithelial integrity and cell extrusion in the early mouse embryo.	ELF5 OCLN	6.61e-04	28	47	2	25588837
Pubmed	Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies.	KALRN NT5DC3	6.61e-04	28	47	2	18839057
Pubmed	Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg.	GDF5 ELF5	7.09e-04	29	47	2	26097038
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	NUP98 CPSF1 DHX8	7.34e-04	130	47	3	35545047
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	NUP98 CPSF1 ALDH4A1 LYRM4 CSNK1D CSNK1E SYNE1 WDR44	8.10e-04	1496	47	8	32877691
Interaction	ANKRD20A4P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	2.22e-07	6	46	3	int:ANKRD20A4P
Interaction	ANKRD20A2P interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	3.87e-07	7	46	3	int:ANKRD20A2P
Interaction	ANKRD20A1 interactions	ANKRD20A2P ANKRD20A4P ANKRD20A1	1.81e-06	11	46	3	int:ANKRD20A1
Interaction	DBNDD1 interactions	CSNK1D CSNK1E	3.05e-05	4	46	2	int:DBNDD1
Interaction	C6orf141 interactions	PLCH1 DSP CSNK1D NSMCE4A	5.73e-05	92	46	4	int:C6orf141
Cytoband	3q21.2	KALRN ITGB5	2.13e-04	21	47	2	3q21.2
Cytoband	9p12	ANKRD20A2P ANKRD20A3P	4.09e-04	29	47	2	9p12
GeneFamily	Ankyrin repeat domain containing	ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD20A1	1.06e-03	242	34	4	403
Coexpression	IWANAGA_CARCINOGENESIS_BY_KRAS_UP	ELF5 ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1 CKMT1A	9.18e-07	192	45	6	MM752
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_C\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ANKRD20A2P ELF5 ANKRD20A4P KALRN ANKRD20A1	7.85e-07	170	45	5	81341bf4fe090af70b2091b6b2579ed08d76e22d
ToppCell	Control-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	1.16e-06	184	45	5	c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCell	COPD-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	1.16e-06	184	45	5	42d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCell	IPF-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	1.22e-06	186	45	5	962c2dada19185628ead77c32fcb07fa95114247
ToppCell	Control-Myeloid-cDC1\|Control / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	1.22e-06	186	45	5	b05c394aa3573ba855abc3066739ca193883b0c3
ToppCell	IPF-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	1.29e-06	188	45	5	47bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCell	IPF-Myeloid-cDC1\|IPF / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	1.29e-06	188	45	5	2331a2bae1383820d598e93aa86c75b101069bac
ToppCell	COPD-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	1.39e-06	191	45	5	3480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCell	COPD-Myeloid-cDC1\|COPD / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1	1.43e-06	192	45	5	bd3d00b094d92463b06023361a71240851a542b8
ToppCell	Basal_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	ANKRD20A2P ANKRD20A3P ANKRD20A4P CKMT1A	2.84e-05	174	45	4	a0060be3940043015dcc49a5157de5541aed24a1
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ELF5 FUT3 DSP CKMT1A	2.84e-05	174	45	4	9e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FUT3 NT5DC3 DSP CKMT1A	2.97e-05	176	45	4	8d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCell	droplet-Lung-nan-3m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INTU ELF5 DSP CKMT1A	3.39e-05	182	45	4	cfba75c1ffc39ac76db9e8e27394731942882b30
ToppCell	droplet-Lung-nan-3m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INTU ELF5 DSP CKMT1A	3.39e-05	182	45	4	7e7c7a26460d3003cdf0c0ffb96208a566aa09a7
ToppCell	droplet-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INTU ELF5 DSP CKMT1A	3.39e-05	182	45	4	d836bfdc298ecd3558a973e393a329eb8bd59d79
ToppCell	Control-Endothelial-VE_Capillary_A\|World / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P KALRN SYNE1	3.61e-05	185	45	4	a28187c2fd23564314b35759479ff2ca21f61485
ToppCell	Control-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD20A1	3.69e-05	186	45	4	3de803dee3ef10eb85a2b47d3f93385214e5b0ff
ToppCell	15-Airway-Epithelial-Neuroendocrine\|Airway / Age, Tissue, Lineage and Cell class	ELF5 FBXL16 DSP CKMT1A	3.77e-05	187	45	4	a7d2f30fe0f19e63d44603ece9890acd11b45e52
ToppCell	Control-Endothelial-VE_Capillary_A\|Control / Disease state, Lineage and Cell class	ANKRD20A2P ANKRD20A3P KALRN SYNE1	3.77e-05	187	45	4	54d7588172ac145ff5045ad9771636729ca3f0ca
ToppCell	droplet-Fat-Scat-18m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELF5 OCLN DSP CKMT1A	4.18e-05	192	45	4	4098b5170c9995718758a082d1b8bcb86d5a289e
ToppCell	droplet-Fat-Scat-18m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELF5 OCLN DSP CKMT1A	4.18e-05	192	45	4	936028fe851e8dd2b906df0210acc574c017b499
ToppCell	droplet-Fat-Scat-18m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELF5 OCLN DSP CKMT1A	4.18e-05	192	45	4	62e55ed0d46b2e7b07dc42399972a099576cbc5f
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ELF5 OCLN PLCH1 DSP	4.18e-05	192	45	4	39804d9ddc67c1b41887752df2503389eae44a1a
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ELF5 OCLN PLCH1 DSP	4.26e-05	193	45	4	ab78fb1603ea6f720ba2d30148fe65dccf271fe1
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELF5 OCLN DSP CKMT1A	4.26e-05	193	45	4	22ebc3f586eb0aabc5785e468c88d7416c624ff4
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ELF5 FBXL16 OCLN PLCH1	4.35e-05	194	45	4	c5ef4ff73b4e51530656002e3a2fb7264cdf533d
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ELF5 OCLN PLCH1 DSP	4.35e-05	194	45	4	c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCell	distal-Epithelial-Proximal_Basal\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ELF5 FBXL16 FUT3 CKMT1A	4.53e-05	196	45	4	c102b28d5d1d90b9f7024cb51114276354be26a5
ToppCell	distal-Epithelial-Proximal_Basal-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ELF5 FBXL16 FUT3 CKMT1A	4.53e-05	196	45	4	a543d4623096cb3f9170dbf7af52381e77aa435e
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ELF5 OCLN PLCH1 DSP	4.62e-05	197	45	4	22b26bac3a99b20c73bfa6e6f81026d064eaa9e8
ToppCell	mLN-(5)_Dendritic_cell-(53)_Lymphoid_DC\|mLN / shred on region, Cell_type, and subtype	ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD20A1	4.71e-05	198	45	4	da84c76afe835aeee39da04b63c03549218b5d91
ToppCell	mLN-Dendritic_cell-Lymphoid_DC\|mLN / Region, Cell class and subclass	ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD20A1	4.71e-05	198	45	4	3965a9f1e8a51a196e5349aaca5fa5ed1cd8ee92
ToppCell	Control-Epithelial_alveolar-AT_2-AT1-AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GDF5 ELF5 SNX32	2.25e-04	117	45	3	c6fc72608d56a389bcd87b5dc98a11e39b79bcb2
ToppCell	AT2_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	ANKRD20A2P ANKRD20A3P ANKRD20A4P	3.13e-04	131	45	3	ff4e618bd944f852bbd34438f740187aca82460f
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-innate_lymphocytic-immature_natural_killer_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CCDC160 TNFSF11 FUT3	4.30e-04	146	45	3	40fac8a298152ec7f7eeeed5a2d28541aea3b338
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM74B PLCH1 USH2A	4.56e-04	149	45	3	cc911b454fe4e4b489885b9920baa7eb01a027ba
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SETD1A ANKRD20A3P SYNE1	5.51e-04	159	45	3	57df5c9b678a15eb5e025e1a80de2e6769cc13d5
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMEM74B FUT3 PLCH1	5.72e-04	161	45	3	f5df8c6a340d5026726804b103e32137f363ca40
ToppCell	368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TNFSF11 ITGB5 SYNE1	5.92e-04	163	45	3	4b8abbad4df040c895e3afb240759ebbc66b4d0e
ToppCell	10x5'-GI_small-bowel-Lymphocytic_NK-NK_CD56bright_CD16-\|GI_small-bowel / Manually curated celltypes from each tissue	RADIL CCDC160 TNFSF11	6.03e-04	164	45	3	36e64e4f717dd59b352c20ff9742ca1e232342bb
ToppCell	PND01-03-samps-Epithelial-Alveolar_epithelial-AT1\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	RADIL OCLN DSP	6.14e-04	165	45	3	b9b6b7b8cd65ba6948a5dd8b715cc7092e0be637
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RADIL PLCH1 KALRN	6.47e-04	168	45	3	2f69e248c6fab1421c0081e01e1920e6ffcde344
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RADIL PLCH1 KALRN	6.47e-04	168	45	3	2d056cfbb470a088a0682576753535fb4528d48f
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	GDF5 DSP CKMT1A	6.47e-04	168	45	3	e870d2e69316406f45112ed0bf324b24f902a99e
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	GDF5 DSP CKMT1A	6.47e-04	168	45	3	403aba73a0f9ffb32252288d075fad8a588ca440
ToppCell	droplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUP98 CPSF1 SNX32	6.81e-04	171	45	3	2e7cc311005958af52f39ca6c310c85b43a85aaf
ToppCell	droplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUP98 CPSF1 SNX32	6.81e-04	171	45	3	4b599f953c8e5b947b2c8bbbf7fe6f9dc388e336
ToppCell	facs-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC160 OCLN CKMT1A	6.92e-04	172	45	3	87a30a219b0a6979abb5fba292a2d8ea946fd849
ToppCell	facs-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC160 OCLN CKMT1A	6.92e-04	172	45	3	5030ac31709cac236bb58f4ef9d545d24690411a
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D122\|Adult / Lineage, Cell type, age group and donor	ANKRD20A8P KALRN DSP	7.04e-04	173	45	3	dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANKRD20A8P PLCH1 NT5DC3	7.04e-04	173	45	3	8ac2e9d39c0f76e674f8bd59d1da246bab4867c8
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	RGPD2 FBXL16 NXT2	7.04e-04	173	45	3	efb8072475000888efe088d00e870c56ffad4172
ToppCell	Tuft-tuft-4\|World / Class top	TMEM74B KALRN NT5DC3	7.16e-04	174	45	3	d6f306ebf66061bf9e9742000bfedce12d277452
ToppCell	facs-Trachea-nan-18m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USH2A DSP CKMT1A	7.28e-04	175	45	3	eb87275da6f61ecb4fbc89421dfd27bead1e0f48
ToppCell	Hippocampus\|World / BrainAtlas - Mouse McCarroll V32	CRYGA NT5DC3 DSP	7.40e-04	176	45	3	f120a703f6d2f2d5f55eae1aea2e6382a485828f
ToppCell	facs-Heart-LA-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYGA KALRN KCNQ4	7.52e-04	177	45	3	1b153fbfe1323dc589de4af73a52149ea5ce6763
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RAPGEF6 FBXL16 SYNE1	7.52e-04	177	45	3	64b8f665fdaf975558af2ad7d9b54d206de8350c
ToppCell	facs-Heart-LA-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYGA KALRN KCNQ4	7.52e-04	177	45	3	32fecefba1a55e1f418c9a055236fa11175c692d
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-GHRL+_NE_precursor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FBXL16 DSP CKMT1A	7.65e-04	178	45	3	32cc4155267baf1b536a61310044e6502d09531f
ToppCell	3'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KALRN KCNQ4 ITGB5	7.77e-04	179	45	3	906555ce2ca264a0215b120c7ff7c9b411de6a34
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	FBXL16 DSP CKMT1A	7.77e-04	179	45	3	06f92c884189197c86793191c05f65e34925c097
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBXL16 USH2A DSP	8.02e-04	181	45	3	cb17c904ab86d56dd30cac9b61acbb3b76f84ded
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	RADIL KALRN DSP	8.02e-04	181	45	3	b244ecaa442bbef51289d8ec574ef08fa9e96318
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-club_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GDF5 ELF5 TMEM74B	8.02e-04	181	45	3	4a0f1b121570430afb100c589657d931184e124f
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-club_cell-club_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GDF5 ELF5 TMEM74B	8.02e-04	181	45	3	34b49092f71128898af3b311170c4ed8adfefcff
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)\|367C / Donor, Lineage, Cell class and subclass (all cells)	RADIL KALRN DSP	8.02e-04	181	45	3	dd79de8098edb385a0f85d0e9621503cdf76ec43
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELF5 DSP CKMT1A	8.15e-04	182	45	3	2ef6889321fd0104d277518d130e19143b3af41c
ToppCell	Control-Epithelial_alveolar-AT_2-AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ELF5 PLCH1 DSP	8.15e-04	182	45	3	e97681a4102f3095d5d9e90ad70f1dc46e90983a
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELF5 DSP CKMT1A	8.15e-04	182	45	3	75608f80fd570da499891dc02f8649d5428b896c
ToppCell	facs-Lung-EPCAM-18m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDF5 ELF5 TMEM74B	8.15e-04	182	45	3	f8eb35eb7f2b8ad47d527ae9ff8a9ddbcd2eedce
ToppCell	facs-Lung-EPCAM-18m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDF5 ELF5 TMEM74B	8.15e-04	182	45	3	6685a0abd9c3a79d03b6a578e5d7fa86a9d74117
ToppCell	367C-Myeloid-Dendritic-cDC1\|367C / Donor, Lineage, Cell class and subclass (all cells)	ANKRD20A3P ANKRD20A4P LYRM4	8.15e-04	182	45	3	6f5228ac47f9ab46d165740cf2655b5ba217acbe
ToppCell	E12.5-Epithelial-epithelial_progenitor_cell-epi_progenitor\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ELF5 OCLN PLCH1	8.28e-04	183	45	3	031b4ffd95114dc10d2932c67d2cfef139b3fd2e
ToppCell	facs-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OCLN NXT2 ITGB5	8.28e-04	183	45	3	d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FUT3 DSP CKMT1A	8.28e-04	183	45	3	bbf27d2f4369031fadacacd6c432c06b1ec5abdb
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLCH1 KALRN USH2A	8.42e-04	184	45	3	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLCH1 KALRN USH2A	8.42e-04	184	45	3	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ANKRD20A3P TNFSF11 ANKRD20A1	8.42e-04	184	45	3	a6f8b42982ec0cf44b950a2cd9715d068eec4ecb
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLCH1 KALRN USH2A	8.42e-04	184	45	3	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLCH1 DSP CKMT1A	8.42e-04	184	45	3	886d2d9bf2fe31207f17e3edc309ef44029924e1
ToppCell	Control-Epithelial_alveolar-AT_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ELF5 PLCH1 DSP	8.42e-04	184	45	3	51e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-goblet\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLCH1 DSP CKMT1A	8.42e-04	184	45	3	936b39377eebea3961d702532779f6cd27953be7
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-ACTC+_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ANKRD20A3P ANKRD20A4P ANKRD20A1	8.42e-04	184	45	3	39168ca2bbf1369c9fe87c67f0aaff5e3cd03151
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ANKRD20A3P TNFSF11 ANKRD20A1	8.42e-04	184	45	3	667846c422cfa27e949a24844a305df859cb6760
ToppCell	Control-Epithelial_alveolar-AT_2-AT2_Progenitor\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ELF5 PLCH1 DSP	8.55e-04	185	45	3	8ca1374501eca01d8468130b74d50abfd4329fbe
ToppCell	10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Mega-Mast\|bone_marrow / Manually curated celltypes from each tissue	RADIL KALRN NT5DC3	8.55e-04	185	45	3	a62ebaff92f2ed27b27b32c27c89cfbe2cb35116
ToppCell	droplet-Fat-Scat-21m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELF5 OCLN DSP	8.68e-04	186	45	3	de88fafac51049ec1920695844d8ce8057940272
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNFSF11 ITGB5 BMP15	8.68e-04	186	45	3	4e983de6d2515082f9e555f4f949cec84281c140
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ELF5 PLCH1 DSP	8.68e-04	186	45	3	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	droplet-Fat-Scat-21m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELF5 OCLN DSP	8.68e-04	186	45	3	59710cff3f6f7c318ee2524b44c1a909f312c25e
ToppCell	droplet-Fat-Scat-21m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELF5 OCLN DSP	8.68e-04	186	45	3	7ff73ab8fed5da779ee9c7bd2e14a8363edb7509
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	OCLN DSP CKMT1A	8.82e-04	187	45	3	380c3e0bc73b266718893a3b3ca207ce5fd31883
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_C\|390C / Donor, Lineage, Cell class and subclass (all cells)	ANKRD20A2P ANKRD20A4P ANKRD20A1	8.82e-04	187	45	3	1e8651e6c547384ace5a66b96c6b24a7f390a7ee
ToppCell	droplet-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OCLN DSP CKMT1A	8.82e-04	187	45	3	5b3c3c6421efd25c740ae121968b5520bbdc07b2
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	OCLN DSP CKMT1A	8.82e-04	187	45	3	796046ff066a9c3847faa9bf1f8beccd956c01f7
ToppCell	facs-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OCLN DSP CKMT1A	8.82e-04	187	45	3	fe9fc21192ede2eea61f419d20ccda254569d0a6
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	OCLN PLCH1 DSP	8.95e-04	188	45	3	0d86044bc340e3efb90d0022dd299873639d831c
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELF5 DSP CKMT1A	8.95e-04	188	45	3	315ce1736e3a84a63a8d5dfa70d411b501cb2532
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	OCLN PLCH1 DSP	8.95e-04	188	45	3	beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OCLN DSP CKMT1A	8.95e-04	188	45	3	14e120b20e76baa07b6510a94f0c2dcdfdd52357
Disease	syndromic X-linked intellectual disability Najm type (implicated_via_orthology)	CSNK1D CSNK1E	3.75e-05	7	40	2	DOID:0060807 (implicated_via_orthology)
Disease	vesicular integral-membrane protein VIP36 measurement	KALRN ITGB5	8.01e-05	10	40	2	EFO_0022012
Disease	Intellectual Disability	SETD1A ALDH4A1 SIN3A ZBTB11 SYNE1	3.32e-04	447	40	5	C3714756

Protein segments in the cluster

Peptide	Gene	Start	Entry
DRLRRSALMLAVYYD	ANKRD20A1	196	Q5TYW2
DRLRRSALMLAVYYD	ANKRD20A8P	196	Q5CZ79
DRLRRSALMLAVYYD	ANKRD20A4P	196	Q4UJ75
DTAMLASYAVYRILR	ALDH4A1	236	P30038
RLYERDDYRGLMSEL	CRYGA	91	P11844
NDRMTYEKLSRALRY	ELF5	221	Q9UKW6
IRSEMSRTRRYYLSV	OCLN	161	Q16625
ASSQLRALYSMYLRK	LTN1	1491	O94822
SMLSRTLSYKYRDLD	RADIL	26	Q96JH8
DRLRRSALMLAVYYD	ANKRD20A2P	196	Q5SQ80
YAMDELRSLTQSYLR	NUP98	1796	P52948
EYMLSLYRTLSDADR	GDF5	171	P43026
RLYSTDMSRAYLTAT	KCNQ4	351	P56696
SLRYMLELYRRSADS	BMP15	66	O95972
RYLYLSTMERSELAK	CPSF1	1406	Q10570
SRRDDLESLGYVLMY	CSNK1D	191	P48730
RDFSLRMGKYRYSLE	KALRN	1221	O60229
RSRARYEMASNPLYR	ITGB5	761	P18084
YDMRRLYTILGSSLF	INTU	506	Q9ULD6
YMRTLLDSIAYGHRL	ERVK-10	331	P87889
YMRTLLDSIAYGHRL	ERVK-24	331	P63145
DRLRRSALMLAVYYD	ANKRD20A3P	196	Q5VUR7
LLTRSGDYYRFLSEM	DSP	1006	P15924
NRALELLRKYYASSM	CCDC160	296	A6NGH7
SLYRAMLRESKRFSA	LYRM4	11	Q9HD34
YLYIMDLRTESLISR	FBXW2	386	Q9UKT8
RLYTERAYRDEMLTT	DHX8	901	Q14562
DLAGRYYRLSEMTEA	CKMT1A	201	P12532
YETMDKRRRALTRLY	NXT2	26	Q9NPJ8
SYLSTMSSLRSLYLR	FBXL16	391	Q8N461
LEALDRYFNLTMSYR	FUT3	146	P21217
YELYMRRLRSTKETT	USH2A	1276	O75445
LRLMSARARYERYSG	RAPGEF6	46	Q8TEU7
KINSYLMEARYSLSR	SYNE1	7141	Q8NF91
LMEARYSLSRFRLLT	SYNE1	7146	Q8NF91
MRRSKAYGERYLASV	RGPD2	1	P0DJD1
RRLSRFADIYMASLS	NT5DC3	491	Q86UY8
KSEDYMYRRTALLRA	SIN3A	1181	Q96ST3
LRSDLSSFDMLRYVE	NSMCE4A	151	Q9NXX6
DSEDMSYLRLTYERL	SETD1A	1436	O15047
ALRRSYSPSMLDYDT	CLASP1	1156	Q7Z460
MSSEESYRAILRYLT	ZBTB11	1	O95625
RLEMYYARLGSHLDR	TMEM74B	161	Q9NUR3
IRLYDLRDLSLSMKY	WDR44	766	Q5JSH3
MSLRRDLYLLLLSYS	PLCH1	211	Q4KWH8
MRRASRDYTKYLRGS	TNFSF11	1	O14788
YMRDSQAAKDLLYRR	SNX32	296	Q86XE0
SRRDDLESLGYVLMY	CSNK1E	191	P49674