Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	monoatomic ion channel activity	BEST3 GRIA1 ASIC3 PKD1L3 LRRC8D CHRNA4 ITPR3 SLC9C1 PIEZO2 KCNT2 SCN1A SCN3A OTOP1 KCNQ1 SLC4A11	2.96e-08	459	109	15	GO:0005216
GeneOntologyMolecularFunction	channel activity	BEST3 GRIA1 ASIC3 PKD1L3 LRRC8D CHRNA4 ITPR3 SLC9C1 PIEZO2 KCNT2 SCN1A SCN3A OTOP1 KCNQ1 SLC4A11	1.70e-07	525	109	15	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	BEST3 GRIA1 ASIC3 PKD1L3 LRRC8D CHRNA4 ITPR3 SLC9C1 PIEZO2 KCNT2 SCN1A SCN3A OTOP1 KCNQ1 SLC4A11	1.75e-07	526	109	15	GO:0022803
GeneOntologyMolecularFunction	monoatomic cation channel activity	GRIA1 ASIC3 PKD1L3 CHRNA4 ITPR3 PIEZO2 KCNT2 SCN1A SCN3A OTOP1 KCNQ1 SLC4A11	3.84e-07	343	109	12	GO:0005261
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC29A3 HNRNPA3 MFSD2B BEST3 GRIA1 ATP13A5 ASIC3 PKD1L3 LRRC8D CHRNA4 ITPR3 SLC9C1 PIEZO2 KCNT2 SLC16A6 SLC16A4 SCN1A SCN3A OTOP1 KCNQ1 SLC4A11	1.38e-06	1180	109	21	GO:0022857
GeneOntologyMolecularFunction	transporter activity	SLC29A3 HNRNPA3 MFSD2B BEST3 GRIA1 ATP13A5 ASIC3 PKD1L3 LRRC8D CHRNA4 ITPR3 SLC9C1 PIEZO2 KCNT2 SLC16A6 SLC16A4 SCN1A SCN3A OTOP1 KCNQ1 SLC4A11	5.55e-06	1289	109	21	GO:0005215
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	BEST3 GRIA1 ATP13A5 ASIC3 PKD1L3 LRRC8D CHRNA4 ITPR3 SLC9C1 PIEZO2 KCNT2 SCN1A SCN3A OTOP1 KCNQ1 SLC4A11	6.23e-06	793	109	16	GO:0015075
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	GRIA1 ATP13A5 ASIC3 PKD1L3 CHRNA4 ITPR3 SLC9C1 PIEZO2 KCNT2 SCN1A SCN3A OTOP1 KCNQ1 SLC4A11	1.53e-05	664	109	14	GO:0008324
GeneOntologyMolecularFunction	tryptophan 5-monooxygenase activity	TPH2 TPH1	2.95e-05	2	109	2	GO:0004510
GeneOntologyMolecularFunction	gated channel activity	BEST3 GRIA1 ASIC3 CHRNA4 ITPR3 PIEZO2 KCNT2 SCN1A KCNQ1	9.05e-05	334	109	9	GO:0022836
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration	GRIA1 GRM1	1.76e-04	4	109	2	GO:0099583
GeneOntologyMolecularFunction	sodium channel activity	ASIC3 SCN1A SCN3A SLC4A11	1.86e-04	52	109	4	GO:0005272
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	GRIA1 ASIC3 PKD1L3 ITPR3 SLC9C1 KCNT2 SCN1A SCN3A KCNQ1 SLC4A11	2.32e-04	465	109	10	GO:0046873
GeneOntologyMolecularFunction	phosphatidylinositol binding	INPPL1 BBS5 DENND1A ITPR3 SH3YL1 PIK3C2A DAPP1 KCNQ1	3.43e-04	316	109	8	GO:0035091
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	TPH2 TPH1	6.09e-04	7	109	2	GO:0016714
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	GRIA1 ASIC3 PKD1L3 ITPR3 SLC9C1 KCNT2 SCN1A SCN3A OTOP1 KCNQ1 SLC4A11	6.35e-04	627	109	11	GO:0022890
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	BEST3 GRIA1 ASIC3 CHRNA4 ITPR3 KCNT2	6.70e-04	193	109	6	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	BEST3 GRIA1 ASIC3 CHRNA4 ITPR3 KCNT2	7.45e-04	197	109	6	GO:0022834
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	BEST3 GRIA1 ASIC3 PKD1L3 ITPR3 SLC9C1 KCNT2 SCN1A SCN3A OTOP1 KCNQ1 SLC4A11	8.85e-04	758	109	12	GO:0015318
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	GRIA1 ASIC3 CHRNA4 ITPR3 KCNT2	1.03e-03	140	109	5	GO:0099094
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR11G2 OR4Q3 OR5A2 OR8K3 GRM1 CCKAR OR11H6 OR1L8 P2RY2 GPR142 GPR153 AGTR1 CALCRL	1.06e-03	884	109	13	GO:0004930
GeneOntologyMolecularFunction	aminopeptidase activity	ANPEP DPP8 BLMH	1.67e-03	43	109	3	GO:0004177
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	ASIC3 SLC9C1 SCN1A SCN3A SLC4A11	2.48e-03	171	109	5	GO:0015081
GeneOntologyMolecularFunction	mismatched DNA binding	MSH6 MLH3	2.57e-03	14	109	2	GO:0030983
GeneOntologyMolecularFunction	D1 dopamine receptor binding	ARRB2 AGTR1	2.57e-03	14	109	2	GO:0031748
GeneOntologyMolecularFunction	sodium ion binding	SCN1A SCN3A	2.57e-03	14	109	2	GO:0031402
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR11G2 OR4Q3 GRIA1 OR5A2 OR8K3 GRM1 PKD1L3 CHRNA4 CCKAR OR11H6 OR1L8 P2RY2 GPR142 GPR153 AGTR1 CALCRL	2.72e-03	1353	109	16	GO:0004888
GeneOntologyBiologicalProcess	monoatomic ion transport	BEST3 GRIA1 ATP13A5 ASIC3 PKD1L3 LRRC8D CHRNA4 CCKAR ITPR3 SLC9C1 PIEZO2 ARRB2 KCNT2 PIK3C2A SCN1A SCN3A AGTR1 OTOP1 KCNQ1 NKAIN1 CALCRL DMD SLC4A11	6.54e-07	1374	109	23	GO:0006811
GeneOntologyBiologicalProcess	monoatomic cation transport	ATP13A5 ASIC3 PKD1L3 CHRNA4 CCKAR ITPR3 SLC9C1 PIEZO2 ARRB2 KCNT2 PIK3C2A SCN1A SCN3A AGTR1 OTOP1 KCNQ1 NKAIN1 CALCRL DMD SLC4A11	2.45e-06	1157	109	20	GO:0006812
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	BEST3 GRIA1 ATP13A5 ASIC3 PKD1L3 LRRC8D CHRNA4 ITPR3 SLC9C1 PIEZO2 KCNT2 PIK3C2A SCN1A SCN3A AGTR1 OTOP1 KCNQ1 DMD SLC4A11	5.58e-06	1115	109	19	GO:0034220
GeneOntologyBiologicalProcess	sensory perception	OR11G2 LHFPL3 OR4Q3 OR5A2 OR8K3 BBS5 ASIC3 GRM1 PKD1L3 CHRNA4 OR11H6 ITPR3 OR1L8 PIEZO2 ARRB2 TMTC4 SCN1A KCNQ1	1.24e-05	1072	109	18	GO:0007600
GeneOntologyBiologicalProcess	metal ion transport	ASIC3 PKD1L3 CHRNA4 CCKAR ITPR3 SLC9C1 ARRB2 KCNT2 PIK3C2A SCN1A SCN3A AGTR1 KCNQ1 NKAIN1 CALCRL DMD SLC4A11	1.91e-05	1000	109	17	GO:0030001
GeneOntologyBiologicalProcess	detection of external stimulus	ASIC3 PKD1L3 PIEZO2 ARRB2 SCN1A OTOP1 KCNQ1	3.76e-05	173	109	7	GO:0009581
GeneOntologyBiologicalProcess	detection of abiotic stimulus	ASIC3 PKD1L3 PIEZO2 ARRB2 SCN1A OTOP1 KCNQ1	4.04e-05	175	109	7	GO:0009582
GeneOntologyBiologicalProcess	detection of mechanical stimulus	ASIC3 PKD1L3 PIEZO2 SCN1A KCNQ1	4.83e-05	75	109	5	GO:0050982
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR11G2 OR4Q3 OR5A2 OR8K3 ASIC3 PKD1L3 OR11H6 OR1L8 PIEZO2 ARRB2 SCN1A KCNQ1	5.91e-05	582	109	12	GO:0050906
GeneOntologyBiologicalProcess	behavior	GRIA1 GRM1 LDLR CHRNA4 CCKAR ITPR3 ORMDL1 ARRB2 P2RY2 SCN1A SCN3A AGTR1 KCNQ1 ZFHX3 DMD	6.93e-05	891	109	15	GO:0007610
GeneOntologyBiologicalProcess	positive regulation of double-strand break repair via homologous recombination	MBTD1 ERCC6 EP400 ARID2	8.51e-05	44	109	4	GO:1905168
GeneOntologyBiologicalProcess	sodium ion transport	ASIC3 SLC9C1 SCN1A SCN3A KCNQ1 NKAIN1 DMD SLC4A11	1.07e-04	275	109	8	GO:0006814
GeneOntologyBiologicalProcess	serotonin metabolic process	SRD5A1 TPH2 TPH1	1.11e-04	18	109	3	GO:0042428
GeneOntologyBiologicalProcess	detection of stimulus	OR11G2 OR4Q3 OR5A2 OR8K3 ASIC3 PKD1L3 OR11H6 OR1L8 PIEZO2 ARRB2 SCN1A OTOP1 KCNQ1	1.13e-04	722	109	13	GO:0051606
GeneOntologyBiologicalProcess	sodium ion transmembrane transport	ASIC3 SLC9C1 SCN1A SCN3A KCNQ1 DMD SLC4A11	1.20e-04	208	109	7	GO:0035725
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	ATP13A5 ASIC3 PKD1L3 ITPR3 SLC9C1 PIEZO2 KCNT2 PIK3C2A SCN1A SCN3A AGTR1 OTOP1 KCNQ1 DMD SLC4A11	1.29e-04	942	109	15	GO:0098655
GeneOntologyBiologicalProcess	regulation of membrane potential	GRIA1 GRM1 CHRNA4 PIEZO2 ARRB2 SCN1A SCN3A KCNQ1 DMD PPP2R3C SLC4A11	1.83e-04	559	109	11	GO:0042391
GeneOntologyBiologicalProcess	determination of adult lifespan	HDAC9 MSH6 SCN1A DMD	1.90e-04	54	109	4	GO:0008340
GeneOntologyBiologicalProcess	detection of mechanical stimulus involved in sensory perception	ASIC3 PIEZO2 SCN1A KCNQ1	2.35e-04	57	109	4	GO:0050974
GeneOntologyBiologicalProcess	primary amino compound metabolic process	SRD5A1 TPH2 TPH1	2.35e-04	23	109	3	GO:1901160
GeneOntologyBiologicalProcess	sensory perception of pain	ASIC3 GRM1 CHRNA4 ARRB2 SCN1A	2.39e-04	105	109	5	GO:0019233
GeneOntologyBiologicalProcess	androgen catabolic process	SRD5A1 HSD17B11	2.74e-04	5	109	2	GO:0006710
GeneOntologyBiologicalProcess	neuronal action potential	GRIA1 CHRNA4 SCN1A SCN3A	3.46e-04	63	109	4	GO:0019228
GeneOntologyBiologicalProcess	monoatomic cation homeostasis	GRIA1 ATP13A5 GRM1 ITPR3 SLC9C1 TMTC4 P2RY2 AGTR1 PKHD1 KCNQ1 DMD SLC4A11	3.51e-04	705	109	12	GO:0055080
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR11G2 OR4Q3 MFSD2B OR5A2 OR8K3 GRM1 ADCY9 CCKAR OR11H6 ITPR3 OR1L8 ARRB2 P2RY2 GPR142 GPR153 AGTR1 KCNQ1 CALCRL	3.62e-04	1395	109	18	GO:0007186
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	GRIA1 ATP13A5 GRM1 ITPR3 SLC9C1 TMTC4 P2RY2 AGTR1 PKHD1 KCNQ1 DMD SLC4A11	4.08e-04	717	109	12	GO:0050801
GeneOntologyBiologicalProcess	intracellular monoatomic ion homeostasis	GRIA1 ATP13A5 GRM1 ITPR3 SLC9C1 TMTC4 P2RY2 PKHD1 KCNQ1 DMD SLC4A11	4.55e-04	622	109	11	GO:0006873
GeneOntologyBiologicalProcess	indole-containing compound metabolic process	SRD5A1 TPH2 TPH1	5.79e-04	31	109	3	GO:0042430
GeneOntologyBiologicalProcess	regulation of receptor recycling	GRIA1 LDLR AGTR1	5.79e-04	31	109	3	GO:0001919
GeneOntologyBiologicalProcess	cellular response to nitrogen compound	HDAC9 INPPL1 SRD5A1 GRIA1 CHRNA4 ITPR3 ARRB2 P2RY2 PIK3C2A AGTR1 OTOP1 KCNQ1	6.23e-04	752	109	12	GO:1901699
GeneOntologyBiologicalProcess	ammonium ion metabolic process	SRD5A1 TPH2 TPH1	6.37e-04	32	109	3	GO:0097164
GeneOntologyBiologicalProcess	intracellular calcium ion homeostasis	GRIA1 ATP13A5 GRM1 ITPR3 TMTC4 P2RY2 PKHD1 DMD	6.43e-04	359	109	8	GO:0006874
GeneOntologyBiologicalProcess	intracellular chemical homeostasis	GRIA1 ATP13A5 GRM1 LRRC8D ITPR3 SLC9C1 ORMDL1 TMTC4 P2RY2 PKHD1 KCNQ1 DMD SLC4A11	6.51e-04	866	109	13	GO:0055082
GeneOntologyBiologicalProcess	action potential	GRIA1 CHRNA4 SCN1A SCN3A KCNQ1 DMD	7.00e-04	201	109	6	GO:0001508
GeneOntologyBiologicalProcess	response to fungicide	SRD5A1 GRIA1	7.59e-04	8	109	2	GO:0060992
GeneOntologyBiologicalProcess	serotonin biosynthetic process	TPH2 TPH1	7.59e-04	8	109	2	GO:0042427
GeneOntologyBiologicalProcess	alkanesulfonate transmembrane transport	LRRC8D SLC16A6	7.59e-04	8	109	2	GO:0042918
GeneOntologyBiologicalProcess	taurine transmembrane transport	LRRC8D SLC16A6	7.59e-04	8	109	2	GO:0015734
GeneOntologyBiologicalProcess	chemical homeostasis	HDAC9 GRIA1 ATP13A5 GRM1 LRRC8D LDLR ITPR3 SLC9C1 ORMDL1 TMTC4 P2RY2 AGTR1 PKHD1 KCNQ1 DMD SLC4A11	8.57e-04	1249	109	16	GO:0048878
GeneOntologyBiologicalProcess	positive regulation of DNA recombination	MBTD1 ERCC6 EP400 ARID2	8.57e-04	80	109	4	GO:0045911
Domain	NPIP	NPIPA1 NPIPA7 NPIPA5 NPIPA3 NPIPA2	1.36e-08	14	112	5	IPR009443
Domain	Trp_5_mOase	TPH2 TPH1	3.56e-05	2	112	2	IPR005963
Domain	ACT_dom	TPH2 TPH1	1.07e-04	3	112	2	IPR002912
Domain	ACT	TPH2 TPH1	1.07e-04	3	112	2	PS51671
Domain	ACT	TPH2 TPH1	1.07e-04	3	112	2	PF01842
Domain	-	TPH2 TPH1	2.12e-04	4	112	2	1.10.800.10
Domain	ArAA_hydroxylase_Fe/CU_BS	TPH2 TPH1	2.12e-04	4	112	2	IPR018301
Domain	BH4_AAA_HYDROXYL_2	TPH2 TPH1	2.12e-04	4	112	2	PS51410
Domain	ArAA_hydroxylase	TPH2 TPH1	2.12e-04	4	112	2	IPR001273
Domain	Biopterin_H	TPH2 TPH1	2.12e-04	4	112	2	PF00351
Domain	Tyrosine_3-monooxygenase-like	TPH2 TPH1	2.12e-04	4	112	2	IPR019773
Domain	Aromatic-AA_hydroxylase_C	TPH2 TPH1	2.12e-04	4	112	2	IPR019774
Domain	BH4_AAA_HYDROXYL_1	TPH2 TPH1	2.12e-04	4	112	2	PS00367
Domain	Na_trans_cytopl	SCN1A SCN3A	5.26e-04	6	112	2	PF11933
Domain	Na_trans_cytopl	SCN1A SCN3A	5.26e-04	6	112	2	IPR024583
Domain	Ion_trans_dom	ITPR3 SLC9C1 SCN1A SCN3A KCNQ1	6.19e-04	114	112	5	IPR005821
Domain	Ion_trans	ITPR3 SLC9C1 SCN1A SCN3A KCNQ1	6.19e-04	114	112	5	PF00520
Pubmed	Novel retinal and cone photoreceptor transcripts revealed by human macular expression profiling.	NPIPA1 NPIPA5 NPIPA3 NPIPA2	1.22e-10	4	117	4	18055785
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CYLD MBTD1 ERCC6 EP400 LDLR ADCY9 MSH6 MLH3 ZFHX4 ARID2 SEC16A ZBTB10 ZFHX3 VPS53 SLC4A11	5.33e-06	1116	117	15	31753913
Pubmed	Genetical genomic determinants of alcohol consumption in rats and humans.	GRM1 CHRNA4 CCKAR ARRB2 TPH2 TPH1	5.41e-06	130	117	6	19874574
Pubmed	Attention-deficit/hyperactivity disorder symptoms in offspring of mothers with impaired serotonin production.	TPH2 TPH1	1.12e-05	2	117	2	20921119
Pubmed	SH3YL1 regulates dorsal ruffle formation by a novel phosphoinositide-binding domain.	INPPL1 SH3YL1	1.12e-05	2	117	2	21624956
Pubmed	Dystrophic mdx mouse myoblasts exhibit elevated ATP/UTP-evoked metabotropic purinergic responses and alterations in calcium signalling.	P2RY2 DMD	1.12e-05	2	117	2	30684640
Pubmed	Missense mutations in Otopetrin 1 affect subcellular localization and inhibition of purinergic signaling in vestibular supporting cells.	P2RY2 OTOP1	1.12e-05	2	117	2	21236346
Pubmed	Association of functional polymorphisms of the human tryptophan hydroxylase 2 gene with risk for bipolar disorder in Han Chinese.	TPH2 TPH1	1.12e-05	2	117	2	17768266
Pubmed	Common variants in the TPH1 and TPH2 regions are not associated with persistent ADHD in a combined sample of 1,636 adult cases and 1,923 controls from four European populations.	TPH2 TPH1	1.12e-05	2	117	2	20213726
Pubmed	Predominant expression of tryptophan hydroxylase 1 mRNA in the pituitary: a postmortem study in human brain.	TPH2 TPH1	1.12e-05	2	117	2	19233335
Pubmed	Beta-arrestin 2-dependent angiotensin II type 1A receptor-mediated pathway of chemotaxis.	ARRB2 AGTR1	1.12e-05	2	117	2	15635042
Pubmed	Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.	SCN1A SCN3A	1.12e-05	2	117	2	24990319
Pubmed	Biased signaling of the angiotensin II type 1 receptor can be mediated through distinct mechanisms.	ARRB2 AGTR1	1.12e-05	2	117	2	21152433
Pubmed	Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.	CNTNAP3B CNTNAP3	1.12e-05	2	117	2	26807827
Pubmed	Family-based association study of TPH1 and TPH2 polymorphisms in autism.	TPH2 TPH1	1.12e-05	2	117	2	16958027
Pubmed	The role of the TPH1 and TPH2 genes for nicotine dependence: a genetic association study in two different age cohorts.	TPH2 TPH1	1.12e-05	2	117	2	17986837
Pubmed	The adaptor protein beta-arrestin2 enhances endocytosis of the low density lipoprotein receptor.	LDLR ARRB2	1.12e-05	2	117	2	12944399
Pubmed	Allosteric modulation of β-arrestin-biased angiotensin II type 1 receptor signaling by membrane stretch.	ARRB2 AGTR1	1.12e-05	2	117	2	25170081
Pubmed	Synthesis of serotonin by a second tryptophan hydroxylase isoform.	TPH2 TPH1	1.12e-05	2	117	2	12511643
Pubmed	The mouse ZFH-4 protein contains four homeodomains and twenty-two zinc fingers.	ZFHX4 ZFHX3	1.12e-05	2	117	2	10873665
Pubmed	mGluR1 in cerebellar Purkinje cells essential for long-term depression, synapse elimination, and motor coordination.	GRIA1 GRM1	1.12e-05	2	117	2	10846166
Pubmed	Investigating the complex interplay between genotype and high-fat-diet feeding in the lactating mammary gland using the Tph1 and Ldlr knockout models.	LDLR TPH1	1.12e-05	2	117	2	33427054
Pubmed	Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants.	TPH2 TPH1	1.12e-05	2	117	2	18923670
Pubmed	Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.	SCN1A SCN3A	1.12e-05	2	117	2	27690330
Pubmed	Expression, purification and enzymatic characterization of the catalytic domains of human tryptophan hydroxylase isoforms.	TPH2 TPH1	1.12e-05	2	117	2	19816759
Pubmed	Regional variation in aortic AT1b receptor mRNA abundance is associated with contractility but unrelated to atherosclerosis and aortic aneurysms.	LDLR AGTR1	1.12e-05	2	117	2	23119030
Pubmed	Common genetic variations in TPH1/TPH2 genes are not associated with schizophrenia in Japanese population.	TPH2 TPH1	1.12e-05	2	117	2	20144688
Pubmed	Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.	SCN1A SCN3A	1.12e-05	2	117	2	23965409
Pubmed	A unique central tryptophan hydroxylase isoform.	TPH2 TPH1	1.12e-05	2	117	2	14563478
Pubmed	Human placenta expresses both peripheral and neuronal isoform of tryptophan hydroxylase.	TPH2 TPH1	1.12e-05	2	117	2	28751217
Pubmed	Cloning of novel splice variants of mouse mGluR1.	GRIA1 GRM1	1.12e-05	2	117	2	10581402
Pubmed	Renin inhibition reduces hypercholesterolemia-induced atherosclerosis in mice.	LDLR AGTR1	1.12e-05	2	117	2	18274671
Pubmed	Maternal serotonin is crucial for murine embryonic development.	TPH2 TPH1	1.12e-05	2	117	2	17182745
Pubmed	The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.	CNTNAP3B CNTNAP3	1.12e-05	2	117	2	31150793
Pubmed	Association between single nucleotide polymorphisms of TPH1 and TPH2 genes, and depressive disorders.	TPH2 TPH1	1.12e-05	2	117	2	29314569
Pubmed	A role for MLH3 in hereditary nonpolyposis colorectal cancer.	MSH6 MLH3	1.12e-05	2	117	2	11586295
Pubmed	Positive selection of a gene family during the emergence of humans and African apes.	NPIPA1 NPIPA8	1.12e-05	2	117	2	11586358
Pubmed	TPH2 and TPH1: association of variants and interactions with heroin addiction.	TPH2 TPH1	1.12e-05	2	117	2	18181017
Pubmed	Association of TPH-1 and TPH-2 gene polymorphisms with suicidal behavior: a systematic review and meta-analysis.	TPH2 TPH1	1.12e-05	2	117	2	25005534
Pubmed	Differential tissue distribution of tryptophan hydroxylase isoforms 1 and 2 as revealed with monospecific antibodies.	TPH2 TPH1	1.12e-05	2	117	2	16581041
Pubmed	Associations of tryptophan hydroxylase gene polymorphisms with irritable bowel syndrome.	TPH2 TPH1	1.12e-05	2	117	2	21073637
Pubmed	Bone marrow transplantation reveals that recipient AT1a receptors are required to initiate angiotensin II-induced atherosclerosis and aneurysms.	LDLR AGTR1	1.12e-05	2	117	2	17158350
Pubmed	Differential regulation of interferon-induced mRNAs and c-myc mRNA by alpha- and gamma-interferons.	IFITM1 IFITM2	1.12e-05	2	117	2	3935435
Pubmed	Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function.	TPH2 TPH1	1.12e-05	2	117	2	14597720
Pubmed	Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout mice.	TPH2 TPH1	1.12e-05	2	117	2	19181488
Pubmed	Genetic, Psychological, and Personal Network Factors Associated With Changes in Binge Drinking Over 2 Years Among Mexican Heritage Adolescents in the USA.	TPH2 TPH1	1.12e-05	2	117	2	29697747
Pubmed	Depletion of endothelial or smooth muscle cell-specific angiotensin II type 1a receptors does not influence aortic aneurysms or atherosclerosis in LDL receptor deficient mice.	LDLR AGTR1	1.12e-05	2	117	2	23236507
Pubmed	Isoform-Specific Substrate Inhibition Mechanism of Human Tryptophan Hydroxylase.	TPH2 TPH1	1.12e-05	2	117	2	29035515
Pubmed	The tryptophan hydroxylase gene influences risk for bipolar disorder but not major depressive disorder: results of meta-analyses.	TPH2 TPH1	1.12e-05	2	117	2	19032713
Pubmed	Localized reduction of atherosclerosis in von Willebrand factor-deficient mice.	VWF LDLR	1.12e-05	2	117	2	11520791
Pubmed	Expression cloning of an ATP receptor from mouse neuroblastoma cells.	LDLR P2RY2	1.12e-05	2	117	2	7685114
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	CNTNAP3B SLC29A3 FPGS CNTNAP3 IFITM1 LRRC8D LDLR ADCY9 SLC16A6 SLC16A4 TMTC4 TMEM70 SEC16A ALG6	1.38e-05	1061	117	14	33845483
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EP400 INPPL1 DENND1A LDLR ADCY9 ITPR3 PCNX2 TTLL4 A4GALT SEC16A PIGW PPP2R3C TOP3B MVB12B	2.16e-05	1105	117	14	35748872
Pubmed	Candidate gene studies of ADHD: a meta-analytic review.	CHRNA4 TPH2 TPH1	2.92e-05	18	117	3	19506906
Pubmed	Transient expression of secretin in serotoninergic neurons of mouse brain during development.	TPH2 TPH1	3.36e-05	3	117	2	15610158
Pubmed	Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).	SCN1A SCN3A	3.36e-05	3	117	2	33895391
Pubmed	Resistance of Transmitted Founder HIV-1 to IFITM-Mediated Restriction.	IFITM1 IFITM2	3.36e-05	3	117	2	27640936
Pubmed	IFITM Proteins Restrict HIV-1 Infection by Antagonizing the Envelope Glycoprotein.	IFITM1 IFITM2	3.36e-05	3	117	2	26387945
Pubmed	SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.	SCN1A SCN3A	3.36e-05	3	117	2	23859570
Pubmed	Myeloid CD34+CD13+ precursor cells transdifferentiate into chondrocyte-like cells in atherosclerotic intimal calcification.	ANPEP LDLR	3.36e-05	3	117	2	20489139
Pubmed	The IFITM proteins inhibit HIV-1 infection.	IFITM1 IFITM2	3.36e-05	3	117	2	21177806
Pubmed	GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.	SCN1A SCN3A	3.36e-05	3	117	2	27816501
Pubmed	Angiotensin II increases adipose angiotensinogen expression.	LDLR AGTR1	3.36e-05	3	117	2	17213477
Pubmed	IFITM proteins are incorporated onto HIV-1 virion particles and negatively imprint their infectivity.	IFITM1 IFITM2	3.36e-05	3	117	2	25422070
Pubmed	Coordinated regulation of IFITM1, 2 and 3 genes by an IFN-responsive enhancer through long-range chromatin interactions.	IFITM1 IFITM2	3.36e-05	3	117	2	28511927
Pubmed	IFITM proteins drive type 2 T helper cell differentiation and exacerbate allergic airway inflammation.	IFITM1 IFITM2	3.36e-05	3	117	2	30365177
Pubmed	Interferon-Induced Transmembrane Proteins Inhibit Infection by the Kaposi's Sarcoma-Associated Herpesvirus and the Related Rhesus Monkey Rhadinovirus in a Cell-Specific Manner.	IFITM1 IFITM2	3.36e-05	3	117	2	34933450
Pubmed	Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus.	IFITM1 IFITM2	3.36e-05	3	117	2	21253575
Pubmed	IFITM Proteins That Restrict the Early Stages of Respiratory Virus Infection Do Not Influence Late-Stage Replication.	IFITM1 IFITM2	3.36e-05	3	117	2	34319159
Pubmed	IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro.	IFITM1 IFITM2	3.36e-05	3	117	2	34321474
Pubmed	Endothelial cell-specific deficiency of Ang II type 1a receptors attenuates Ang II-induced ascending aortic aneurysms in LDL receptor-/- mice.	LDLR AGTR1	3.36e-05	3	117	2	21252156
Pubmed	Alphavirus Restriction by IFITM Proteins.	IFITM1 IFITM2	3.36e-05	3	117	2	27219333
Pubmed	Agonist-promoted internalization of a ternary complex between calcitonin receptor-like receptor, receptor activity-modifying protein 1 (RAMP1), and beta-arrestin.	ARRB2 CALCRL	3.36e-05	3	117	2	11535606
Pubmed	The IFITM protein family in adaptive immunity.	IFITM1 IFITM2	3.36e-05	3	117	2	31792954
Pubmed	Association between Serotonin-Related Polymorphisms in 5HT2A, TPH1, TPH2 Genes and Bipolar Disorder in Korean Population.	TPH2 TPH1	3.36e-05	3	117	2	20396435
Pubmed	Angiotensin II increases vascular proteoglycan content preceding and contributing to atherosclerosis development.	LDLR AGTR1	3.36e-05	3	117	2	18033753
Pubmed	Phenylalanine hydroxylase contributes to serotonin synthesis in mice.	TPH2 TPH1	3.36e-05	3	117	2	33993565
Pubmed	Autoantibodies against aromatic amino acid hydroxylases in patients with autoimmune polyendocrine syndrome type 1 target multiple antigenic determinants and reveal regulatory regions crucial for enzymatic activity.	TPH2 TPH1	3.36e-05	3	117	2	23182718
Pubmed	IFITMs restrict the replication of multiple pathogenic viruses.	IFITM1 IFITM2	3.36e-05	3	117	2	24076421
Pubmed	IFITM-2 and IFITM-3 but not IFITM-1 restrict Rift Valley fever virus.	IFITM1 IFITM2	3.36e-05	3	117	2	23720721
Pubmed	Genetic variants and susceptibility to neurological complications following West Nile virus infection.	ANPEP SCN1A	3.36e-05	3	117	2	21881118
Pubmed	Sodium channels SCN1A, SCN2A and SCN3A in familial autism.	SCN1A SCN3A	3.36e-05	3	117	2	12610651
Pubmed	IFITM proteins restrict antibody-dependent enhancement of dengue virus infection.	IFITM1 IFITM2	3.36e-05	3	117	2	22479637
Pubmed	The C-terminal sequence of IFITM1 regulates its anti-HIV-1 activity.	IFITM1 IFITM2	3.36e-05	3	117	2	25738301
Pubmed	Agonist-stimulated and tonic internalization of metabotropic glutamate receptor 1a in human embryonic kidney 293 cells: agonist-stimulated endocytosis is beta-arrestin1 isoform-specific.	GRM1 ARRB2	3.36e-05	3	117	2	11723231
Pubmed	Primate lentiviruses are differentially inhibited by interferon-induced transmembrane proteins.	IFITM1 IFITM2	3.36e-05	3	117	2	25463599
Pubmed	The Inhibition of HIV-1 Entry Imposed by Interferon Inducible Transmembrane Proteins Is Independent of Co-Receptor Usage.	IFITM1 IFITM2	3.36e-05	3	117	2	30087232
Pubmed	Transient exposure of neonatal female mice to testosterone abrogates the sexual dimorphism of abdominal aortic aneurysms.	LDLR AGTR1	3.36e-05	3	117	2	22539767
Pubmed	IFITM proteins incorporated into HIV-1 virions impair viral fusion and spread.	IFITM1 IFITM2	3.36e-05	3	117	2	25464829
Pubmed	Association of TPH1, TPH2, and 5HTTLPR with PTSD and depressive symptoms.	TPH2 TPH1	3.36e-05	3	117	2	22483952
Pubmed	Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.	SCN1A SCN3A	3.36e-05	3	117	2	18784617
Pubmed	Lessons in self-defence: inhibition of virus entry by intrinsic immunity.	IFITM1 IFITM2	3.36e-05	3	117	2	34646033
Pubmed	Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.	SCN1A SCN3A	3.36e-05	3	117	2	17544618
Pubmed	Serotonin-reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local anti-resorptive effect.	TPH2 TPH1	3.36e-05	3	117	2	27595322
Pubmed	Tryptophan hydroxylase 1 knockout and tryptophan hydroxylase 2 polymorphism: effects on hypoxic pulmonary hypertension in mice.	TPH2 TPH1	3.36e-05	3	117	2	17675372
Pubmed	The Interferon-Stimulated Gene IFITM3 Restricts Infection and Pathogenesis of Arthritogenic and Encephalitic Alphaviruses.	IFITM1 IFITM2	3.36e-05	3	117	2	27440901
Pubmed	Neural mechanism underlies CYLD modulation of morphology and synaptic function of medium spiny neurons in dorsolateral striatum.	CYLD GRIA1	3.36e-05	3	117	2	36846565
Pubmed	IFITM proteins inhibit HIV-1 protein synthesis.	IFITM1 IFITM2	3.36e-05	3	117	2	30266929
Pubmed	Association between tryptophan hydroxylase 2 polymorphism and anger-related personality traits among young Korean women.	TPH2 TPH1	3.36e-05	3	117	2	20628266
Pubmed	Vascular dysfunction in human and rat cirrhosis: role of receptor-desensitizing and calcium-sensitizing proteins.	ARRB2 AGTR1	3.36e-05	3	117	2	17256744
Cytoband	16p13.11	NPIPA1 NPIPA5 NPIPA3 NPIPA2	3.42e-07	23	117	4	16p13.11
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	CNTNAP3B VWF CNTNAP3 IFITM2 DENND1A KCNT2 PIK3C2A CALCRL	4.36e-08	192	117	8	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D231\|Adult / Lineage, Cell type, age group and donor	CNTNAP3B PKD1L3 BCL6B PIEZO2 ZFHX4 SCN3A CALCRL	4.63e-07	178	117	7	c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B CNTNAP3 BCL6B PIEZO2 ZFHX4 SCN3A CALCRL	5.38e-07	182	117	7	53c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B CNTNAP3 GRIA1 CHRNA4 PIEZO2 SCN3A CALCRL	5.58e-07	183	117	7	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNTNAP3B VWF CNTNAP3 PKD1L3 PIEZO2 SCN3A CALCRL	9.47e-07	198	117	7	b3a020522e064bb61949d38e442f24026e339364
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNTNAP3B VWF CNTNAP3 PKD1L3 PIEZO2 SCN3A CALCRL	9.47e-07	198	117	7	fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HDAC9 CNTNAP3B VWF CNTNAP3 A4GALT CALCRL	5.32e-06	167	117	6	d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D175\|Adult / Lineage, Cell type, age group and donor	HDAC9 CNTNAP3B VWF BCL6B A4GALT CALCRL	5.69e-06	169	117	6	e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCell	Endothelial-B-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	CNTNAP3B VWF BCL6B PIEZO2 SCN3A CALCRL	5.69e-06	169	117	6	8889c9e8af1ab0b093d57b69abd80b59b3461be9
ToppCell	CD8+_Memory_T_cell-FLU-3\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	MSH6 WDR75 SLC16A4 TTLL4 CENPI ALG6	6.30e-06	172	117	6	45ac433dbb3796f69e886c04457b2971403050ee
ToppCell	Endothelial-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	CNTNAP3B CNTNAP3 PIEZO2 ZFHX4 SCN3A CALCRL	6.30e-06	172	117	6	d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CASS4 HDAC9 CNTNAP3B CNTNAP3 GRIA1 ZFHX4	7.91e-06	179	117	6	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B VWF MFSD2B BCL6B NPIPA3 CALCRL	7.91e-06	179	117	6	d2db9e70b780643f1e004c41a70464d0abe26088
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF CNTNAP3 GRIA1 BCL6B PIEZO2 CALCRL	8.70e-06	182	117	6	fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B LHFPL3 CNTNAP3 GRM1 PIEZO2 TPH2	9.26e-06	184	117	6	23515c28e1f42aab29cef9e5b4a7f45bda7f5520
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF CNTNAP3 GRIA1 BCL6B PIEZO2 CALCRL	9.26e-06	184	117	6	453295362888c9a59d0e73c7a5b15914c50ff591
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SRD5A1 GRIA1 PTPN21 BCL6B DAPP1 ZBTB10	9.84e-06	186	117	6	39e475a3c167b33daa63b0c1bfa32451c5f46635
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B CNTNAP3 CHRNA4 PIEZO2 SCN3A CALCRL	9.84e-06	186	117	6	40070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SRD5A1 GRIA1 PTPN21 BCL6B DAPP1 ZBTB10	9.84e-06	186	117	6	02418c50fdcca549bf73dedf6199ab4a27862a9b
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 BCL6B SCN3A A4GALT CALCRL	1.08e-05	189	117	6	0d18ea72bd58d32a8ab9a61cf97f5786642f804b
ToppCell	COVID-19-lung-Lymphatic_EC\|lung / Disease (COVID-19 only), tissue and cell type	CNTNAP3B CNTNAP3 PIEZO2 ZFHX4 SCN3A CALCRL	1.08e-05	189	117	6	c8db9aaf54ea3cc96c4a2f777c3389e0f31f67f3
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CNTNAP3B VWF CNTNAP3 IFITM2 KCNT2 CALCRL	1.08e-05	189	117	6	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel\|Adult / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 PKD1L3 PIEZO2 SCN3A CALCRL	1.11e-05	190	117	6	91bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCell	COVID-19-lung-Lymphatic_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CNTNAP3B CNTNAP3 PIEZO2 ZFHX4 SCN3A CALCRL	1.18e-05	192	117	6	cbe57cda44232b183821ac633b60a2668265e616
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_venous_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	HDAC9 CNTNAP3B VWF CNTNAP3 BCL6B CALCRL	1.29e-05	195	117	6	ca2cf2c10db1ad17aa0a2e30aa7079a7ad751ea6
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IFITM1 COL6A5 IFITM2 PIEZO2 ZFHX4 DMD	1.33e-05	196	117	6	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IFITM1 COL6A5 IFITM2 PIEZO2 ZFHX4 DMD	1.33e-05	196	117	6	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VWF CNTNAP3 PKD1L3 PIEZO2 SCN3A CALCRL	1.33e-05	196	117	6	09a7edf4a7defb7fe70d9777dd9500ee8421ff31
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VWF CNTNAP3 PKD1L3 PIEZO2 SCN3A CALCRL	1.33e-05	196	117	6	e50d2c66d5c5cd25fdfecdcc4c8506a1d0a85755
ToppCell	COVID-19_Mild-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	ADCY9 NPIPA8 NPIPA5 NPIPA2 TPH1	1.92e-05	124	117	5	5ef9eb806fb2c8ee5aae0a75503d244b08ee10d4
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_STALK\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	VWF ITPR3 BCL6B SLC16A4 KCNQ1	2.50e-05	131	117	5	308ddb7fe113eac5dbeb9cb0b688d9e09275ce5e
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_1\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	VWF ITPR3 BCL6B SLC16A4 KCNQ1	2.59e-05	132	117	5	06e7337de35bd7120655a22b6020604ad004c4e1
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_bronchial_vessel-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HDAC9 CNTNAP3B VWF CNTNAP3 CALCRL	3.93e-05	144	117	5	748f4efc59f7afbce6c497524f36d852b8b1d637
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ANPEP ASIC3 TRDV3 A4GALT CARD6	5.25e-05	153	117	5	e7d20c88466ff81db613869cf7a6a4bb95fd6c2f
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CNTNAP3 LDLR PIEZO2 KCNQ1 CALCRL	5.42e-05	154	117	5	c6ecc46b99a783373729f7fae0b23216148ffb78
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LHFPL3 C1QL2 SCN1A SCN3A CALCRL	5.59e-05	155	117	5	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	ASIC3 LDLR ITPR3 MLH3 SEC16A	6.30e-05	159	117	5	655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A5 COL6A5 KCNT2 ZFHX4 PKHD1	6.49e-05	160	117	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	356C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CATSPERE GRIA1 COL6A5 PIEZO2 AGTR1	6.49e-05	160	117	5	0293b244c063a62819690bf22bbc2681f8d15252
ToppCell	356C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CATSPERE GRIA1 COL6A5 PIEZO2 AGTR1	6.49e-05	160	117	5	3eaae86fa08f7651021316f8e5811bf48055591e
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	VWF ITPR3 BCL6B SLC16A4 KCNQ1	6.49e-05	160	117	5	04714d0b9bad4c11fa193ed168e2d84a4df39e2e
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP13A5 COL6A5 KCNT2 ZFHX4 PKHD1	6.49e-05	160	117	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Endothelial-B-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	PTCHD3 BCL6B PIEZO2 SCN3A CALCRL	8.18e-05	168	117	5	4977c3837fbb1f36c89fddd5764e37290ac25ad8
ToppCell	Endothelial-B-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	CNTNAP3B PTCHD3 PIEZO2 SCN3A CALCRL	8.41e-05	169	117	5	95c617143e1fbdd1d55a93ffdcc210e0be37cf2f
ToppCell	356C-Endothelial_cells-Endothelial-B_(Artery)\|356C / Donor, Lineage, Cell class and subclass (all cells)	CNTNAP3B VWF BCL6B A4GALT CALCRL	8.41e-05	169	117	5	605cc2638271803cf1d972ab3fa8f13f89666376
ToppCell	356C-Endothelial_cells-Endothelial-B_(Artery)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	CNTNAP3B VWF BCL6B A4GALT CALCRL	8.41e-05	169	117	5	337be3bf485b54afad86e256cb0c4c1d0c2a9a2a
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF CNTNAP3 NPIPA7 BCL6B CALCRL	8.89e-05	171	117	5	b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNTNAP3B VWF BCL6B A4GALT CALCRL	9.13e-05	172	117	5	de9b11ab109d04937186c09772cec9105a935f95
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IFITM1 COL6A5 IFITM2 NPIPA5 AGTR1	9.13e-05	172	117	5	afa36501d48b1456c511fa0d5d326ec05bdc380f
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D122\|Adult / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 PIEZO2 SCN3A CALCRL	9.39e-05	173	117	5	dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCell	FLU-Healthy-3\|FLU / Virus stimulation, Condition and Cluster	MSH6 SLC16A4 TTLL4 CENPI ALG6	9.39e-05	173	117	5	32b8e5b400885dbeba57a7cb2c18d882664dc285
ToppCell	FLU-Healthy-3\|Healthy / Virus stimulation, Condition and Cluster	MSH6 SLC16A4 TTLL4 CENPI ALG6	9.39e-05	173	117	5	26e89ac86922f1cd0100cf4d1cce37e74dd31c88
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANPEP ATP13A5 AGTR1 ZFHX3 DMD	9.39e-05	173	117	5	2415b6ff49f334da570577d4e93484d024a3dbd5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANPEP ATP13A5 AGTR1 ZFHX3 DMD	9.39e-05	173	117	5	2acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCell	Endothelial-B-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	PTCHD3 PIEZO2 ZFHX4 SCN3A CALCRL	9.39e-05	173	117	5	a81992965137195d20fc498f750975303961a828
ToppCell	3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF CNTNAP3 IFITM1 IFITM2 CALCRL	9.39e-05	173	117	5	b57d14e2c2368304cb903562d06ce8228f53857c
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF INPPL1 BEST3 PIEZO2 TPH1	9.91e-05	175	117	5	0992de1c7bffcb6890584357a7a0a8955927da6c
ToppCell	metastatic_Lymph_Node-Endothelial_cells\|metastatic_Lymph_Node / Location, Cell class and cell subclass	VWF CNTNAP3 BCL6B PIEZO2 CALCRL	1.05e-04	177	117	5	71bf5d4bc67bda37a0499e5ec01af7dd5254041d
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CNTNAP3 IFITM2 ZFHX4 A4GALT CARD6	1.05e-04	177	117	5	dfaed388926ce050730492a532824af68bf4feff
ToppCell	COVID-19-Heart-Lymph_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CNTNAP3B CNTNAP3 PIEZO2 SCN3A CALCRL	1.05e-04	177	117	5	326fde0734ef0d7272693966d346ca479b9d8147
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	VWF ITPR3 BCL6B KCNQ1	1.06e-04	93	117	4	4eca07c288fe15531a685522c61746671c1c87fb
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	VWF ITPR3 BCL6B KCNQ1	1.06e-04	93	117	4	312291db0fab96952017f9faf2057c28f3719556
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	VWF ITPR3 BCL6B KCNQ1	1.06e-04	93	117	4	8f65381291fc92b56bf0fc2caac013a54560737b
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B PKD1L3 PIEZO2 SCN3A CALCRL	1.07e-04	178	117	5	ad3de3e03a401dac64431a541899445262246347
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega\|lymph-node_spleen / Manually curated celltypes from each tissue	VWF MFSD2B COL6A5 PKD1L3 AGTR1	1.10e-04	179	117	5	4e0cf069bc47328eda753a4edc7e89b8915d52bb
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Mesenchymal-Mes-Pericyte\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANPEP IFITM1 IFITM2 A4GALT SLC4A11	1.13e-04	180	117	5	e5c50d85e8df4e15f3e58f1f1d5aa25a375735de
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Mesenchymal-Mes-Pericyte-Peri_L1-6_MUSTN1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANPEP IFITM1 IFITM2 A4GALT SLC4A11	1.13e-04	180	117	5	f5d757786a3be20756ad8b30edd53ff80b824974
ToppCell	3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF IFITM1 IFITM2 A4GALT CALCRL	1.13e-04	180	117	5	efc4c5a4dea456527526bbfd88cf70d803893671
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HDAC9 CNTNAP3B VWF CNTNAP3 CALCRL	1.13e-04	180	117	5	27e8bbee388e64dd79d70b160b76d45b1f398006
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HDAC9 CNTNAP3B VWF A4GALT CALCRL	1.16e-04	181	117	5	2c660fcf0404c155955b67ab2958d6e6b0e30024
ToppCell	pdx-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CASS4 CNTNAP3B CNTNAP3 GRIA1 ZFHX4	1.19e-04	182	117	5	7b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF IFITM1 IFITM2 BCL6B CALCRL	1.22e-04	183	117	5	ce8be9418b473ea94ec806edc7a2078cc30c1703
ToppCell	3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF CNTNAP3 IFITM1 IFITM2 CALCRL	1.22e-04	183	117	5	858682df5592c6856487487a7baabd6e60e63a38
ToppCell	3'-Adult-SmallIntestine-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF CNTNAP3 IFITM1 IFITM2 CALCRL	1.22e-04	183	117	5	f8212bf8a8b8312434ae030261c558c147f61747
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRM1 PIEZO2 ZFHX4 PKHD1 DMD	1.25e-04	184	117	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	3'_v3-GI_small-bowel-Myeloid_Dendritic-DC1\|GI_small-bowel / Manually curated celltypes from each tissue	HDAC9 ANPEP DAPP1 CALCRL DMD	1.25e-04	184	117	5	8e393eea7240584a3cef718bee094e2705ec1891
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CNTNAP3B VWF CNTNAP3 BCL6B CALCRL	1.25e-04	184	117	5	a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRM1 PIEZO2 ZFHX4 PKHD1 DMD	1.25e-04	184	117	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRM1 PIEZO2 ZFHX4 PKHD1 DMD	1.25e-04	184	117	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 SCN3A AGTR1 ZFHX3 DMD	1.29e-04	185	117	5	51dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 SCN3A AGTR1 ZFHX3 DMD	1.29e-04	185	117	5	a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VWF IFITM1 IFITM2 BCL6B FAM111A	1.32e-04	186	117	5	422d24e3e1a9397bb7d5c7ef75de2fd7ae8e136d
ToppCell	356C-Endothelial_cells-Endothelial-E-\|356C / Donor, Lineage, Cell class and subclass (all cells)	VWF CNTNAP3 BCL6B CARD6 CALCRL	1.32e-04	186	117	5	2e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell	356C-Endothelial_cells-Endothelial-E\|356C / Donor, Lineage, Cell class and subclass (all cells)	VWF CNTNAP3 BCL6B CARD6 CALCRL	1.32e-04	186	117	5	c3449e54454009973818fc1101933c6f0168258c
ToppCell	3'_v3-bone_marrow-Hematopoietic_Erythro-Mega\|bone_marrow / Manually curated celltypes from each tissue	VWF MFSD2B COL6A5 AGTR1 A4GALT	1.32e-04	186	117	5	9ff3c30b1728707bb8f9422941333fe3b2c430f4
ToppCell	10x5'-Liver-Myeloid_Dendritic-DC1\|Liver / Manually curated celltypes from each tissue	HDAC9 ANPEP DAPP1 CALCRL DMD	1.32e-04	186	117	5	e823529ffd06352c6bdec102f221fdf27f7c7369
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VWF IFITM1 IFITM2 BCL6B FAM111A	1.32e-04	186	117	5	65da0666a10a59f8cc379589860a2e98fe487754
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B PKD1L3 PIEZO2 SCN3A CALCRL	1.32e-04	186	117	5	20340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VWF IFITM1 IFITM2 BCL6B FAM111A	1.32e-04	186	117	5	dc84fef1ca2f5d5d818b76a3321559e87d1c4a4d
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B LHFPL3 GRM1 PIEZO2 PKHD1	1.35e-04	187	117	5	85f1678338a47d91e296f0620d4887f057eb7e70
ToppCell	metastatic_Lymph_Node-Endothelial_cells-Tumor_ECs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	CNTNAP3B VWF CNTNAP3 A4GALT CALCRL	1.35e-04	187	117	5	2713f526f86911fbbf6c7a3e69230f2e6bde31c3
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HDAC9 CNTNAP3B VWF CNTNAP3 CALCRL	1.35e-04	187	117	5	e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCell	367C-Endothelial_cells-Endothelial-D\|367C / Donor, Lineage, Cell class and subclass (all cells)	CNTNAP3B VWF IFITM2 BCL6B CALCRL	1.35e-04	187	117	5	1342bc614bc4045263c2eb0a535a1dd6c64e7abe
ToppCell	367C-Endothelial_cells-Endothelial-D-\|367C / Donor, Lineage, Cell class and subclass (all cells)	CNTNAP3B VWF IFITM2 BCL6B CALCRL	1.35e-04	187	117	5	7aa206262b14b9f2aaa99e59da38b96c3594d2c9
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-endo_capillary_(2)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CNTNAP3B VWF BCL6B CARD6 CALCRL	1.35e-04	187	117	5	106f50ad85a92403037214f0e94702230284837f
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	VWF ANPEP BCL6B CARD6 CALCRL	1.35e-04	187	117	5	03de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D175\|Adult / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 PKD1L3 PIEZO2 CALCRL	1.35e-04	187	117	5	1e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell	COVID-19-lung-Vein_EC\|lung / Disease (COVID-19 only), tissue and cell type	HDAC9 CNTNAP3B VWF PIK3C2A CALCRL	1.39e-04	188	117	5	d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 PIEZO2 SCN3A CALCRL	1.39e-04	188	117	5	c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 PIEZO2 SCN3A CALCRL	1.39e-04	188	117	5	2db80767903703e7e0a1a37c598f7877a909ee94
Drug	gabapentin	ANPEP GRIA1 ASIC3 GRM1 PKD1L3 ITPR3 SCN3A TPH1	1.93e-06	169	112	8	CID000003446
Disease	Mental Depression	HDAC9 SLC29A3 SRD5A1 GRIA1 GRM1 CHRNA4 ARRB2 TPH2 TPH1	3.88e-07	254	107	9	C0011570
Disease	Depressive disorder	HDAC9 SLC29A3 SRD5A1 GRIA1 GRM1 CHRNA4 ARRB2 TPH2 TPH1	1.14e-06	289	107	9	C0011581
Disease	autism spectrum disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3 ITPR3 WDR75 SCN1A TPH2 TPH1	1.42e-06	152	107	7	DOID:0060041 (implicated_via_orthology)
Disease	tea consumption measurement	OR5A2 DENND1A MSH6 PKHD1 ZFHX3 ALG6	7.82e-06	129	107	6	EFO_0010091
Disease	Alcoholic Intoxication, Chronic	VWF SRD5A1 GRM1 CHRNA4 CCKAR NKAIN1 TPH1	5.67e-05	268	107	7	C0001973
Disease	haptoglobin measurement	PKD1L3 TLE7 ZFHX3	5.88e-05	21	107	3	EFO_0004640
Disease	Attention Deficit Disorder	GRM1 CHRNA4 TPH2	6.79e-05	22	107	3	C0041671
Disease	Minimal Brain Dysfunction	GRM1 CHRNA4 TPH2	6.79e-05	22	107	3	C1321905
Disease	Endometrial cancer	MSH6 MLH3	7.78e-05	4	107	2	cv:C0007103
Disease	ENDOMETRIAL CANCER	MSH6 MLH3	7.78e-05	4	107	2	608089
Disease	Endometrial carcinoma	MSH6 MLH3	7.78e-05	4	107	2	cv:C0476089
Disease	Attention deficit hyperactivity disorder	GRM1 CHRNA4 TPH2	8.88e-05	24	107	3	C1263846
Disease	obesity (implicated_via_orthology)	CCKAR ITPR3 ZFHX4 GUCY2C SEC16A ZFHX3	1.37e-04	215	107	6	DOID:9970 (implicated_via_orthology)
Disease	LDL cholesterol change measurement	PKD1L3 LDLR	2.70e-04	7	107	2	EFO_0007804
Disease	stachydrine measurement	LHFPL3 PKHD1	3.60e-04	8	107	2	EFO_0021169
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3	3.60e-04	8	107	2	DOID:0060308 (implicated_via_orthology)
Disease	Schizophrenia	HDAC9 HNRNPA3 GRIA1 PTPN21 GRM1 CHRNA4 CCKAR GPR153 TPH2 TOP3B TPH1	3.68e-04	883	107	11	C0036341
Disease	Unipolar Depression	HDAC9 ANPEP GRM1 CCKAR TPH2 TPH1	3.72e-04	259	107	6	C0041696
Disease	lysophosphatidylcholine 20:3 measurement	NPIPA1 GRIA1 NPIPA2	4.15e-04	40	107	3	EFO_0010362
Disease	Lynch Syndrome	MSH6 MLH3	4.61e-04	9	107	2	C4552100
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN3A	5.75e-04	10	107	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN3A	5.75e-04	10	107	2	DOID:0080422 (implicated_via_orthology)
Disease	triglycerides to total lipids in medium LDL percentage	NPIPA1 LDLR NPIPA2	8.03e-04	50	107	3	EFO_0022334
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN3A	8.40e-04	12	107	2	DOID:0060170 (implicated_via_orthology)
Disease	triglycerides to total lipids in large LDL percentage	NPIPA1 LDLR NPIPA2	8.51e-04	51	107	3	EFO_0022331
Disease	phosphatidylcholine 40:7 measurement	NPIPA1 NPIPA2	9.90e-04	13	107	2	EFO_0021477
Disease	Paranoid Schizophrenia	CCKAR TPH2	9.90e-04	13	107	2	C0036349
Disease	Antithrombotic agent use measurement	HDAC9 LDLR ZFHX3	1.06e-03	55	107	3	EFO_0009925
Disease	atrial fibrillation (is_implicated_in)	VWF KCNQ1	1.15e-03	14	107	2	DOID:0060224 (is_implicated_in)
Disease	Testicular Germ Cell Tumor	PRDM14 ALOX12B	1.15e-03	14	107	2	C1336708
Disease	triglycerides to total lipids in small VLDL percentage	NPIPA1 LDLR NPIPA2	1.24e-03	58	107	3	EFO_0022338
Disease	retinal layer thickness measurement	NPIPA1 PIK3C2A NPIPA2	1.37e-03	60	107	3	EFO_0600002
Disease	partial epilepsy	ADCY9 SCN1A	1.71e-03	17	107	2	EFO_0004263
Disease	breast carcinoma (is_marker_for)	SRD5A1 MSH6 ZFHX3	1.80e-03	66	107	3	DOID:3459 (is_marker_for)
Disease	risk-taking behaviour	GRIA1 PKD1L3 DENND1A MSH6 KCNT2 ASB3 ZBTB10 ZFHX3 MVB12B	1.87e-03	764	107	9	EFO_0008579
Disease	Alcohol abuse	LDLR CCKAR TPH2	1.88e-03	67	107	3	C0085762
Disease	stroke	HDAC9 ASB3 DAPP1 ZFHX3	1.90e-03	144	107	4	EFO_0000712
Disease	sphingosine 1-phosphate measurement	C1QL2 DMD	1.92e-03	18	107	2	EFO_0800185
Disease	bipolar disorder (is_marker_for)	VWF TPH2	2.14e-03	19	107	2	DOID:3312 (is_marker_for)
Disease	factor VIII measurement, Ischemic stroke	HDAC9 VWF	2.14e-03	19	107	2	EFO_0004630, HP_0002140
Disease	electroencephalogram measurement	HDAC9 PCNX2 DMD	2.49e-03	74	107	3	EFO_0004357
Disease	colorectal carcinoma (is_implicated_in)	ERCC6 MSH6	2.87e-03	22	107	2	DOID:0080199 (is_implicated_in)
Disease	anxiety disorder (implicated_via_orthology)	SCN1A SCN3A	2.87e-03	22	107	2	DOID:2030 (implicated_via_orthology)
Disease	Headache, type 2 diabetes mellitus	DENND1A KCNQ1	3.14e-03	23	107	2	HP_0002315, MONDO_0005148
Disease	Lynch syndrome (is_implicated_in)	MSH6 MLH3	3.41e-03	24	107	2	DOID:3883 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
TLAVYTFFFACLIGR	BEST3	241	Q8N1M1
FHVCITSYTQFFRGL	EP400	1191	Q96L91
IYKSSCSIDVTFFPF	CHRNA4	156	P43681
YILTKCNSTRFEFIF	BBS5	96	Q8N3I7
RAALVSSFGVFKYLT	ATP13A5	896	Q4VNC0
DVCFFFKTTVSSGVF	CNTNAP3	816	Q9BZ76
AAFGYCTKTLTLTFY	CATSPERE	641	Q5SY80
CRLYFGALFKAISAF	CASS4	676	Q9NQ75
RKFSFGTCVRAVVIY	DDX4	386	Q9NQI0
CTLFIIGFKFTFFVS	A4GALT	21	Q9NPC4
AFFIACVTSFSIFEK	ALG6	396	Q9Y672
FGNYLCKIASASVSF	AGTR1	96	P30556
ILTSTGFYKCLRTVF	ARID2	561	Q68CP9
YVFKGSSTVRFTCKE	ANPEP	101	P15144
DFIFGSAVCKTTTYF	CCKAR	106	P32238
RYLFKQVASSTGFCD	DMD	3216	P11532
FLLAYCSSKFAAVGF	HSD17B11	181	Q8NBQ5
DRKVFVTLTCAFRYG	ARRB2	51	P32121
YFSDIVGFTTICKYS	GUCY2C	826	P25092
LICFSIAALFTKRYS	ITPR3	2246	Q14573
TVFLRSYKFAISLCT	NPIPA1	46	Q9UND3
SFYVCTAVRKFFFFL	PPP2R3C	216	Q969Q6
SEFKCFLGIIFLSGY	ERCC6	646	P0DP91
EIKTISFSGCFLQFY	OR11H6	106	Q8NGC7
KTIASCFSVFAISFF	KCNQ1	326	P51787
GVRDAFYSKTKRFCS	MBTD1	61	Q05BQ5
CLGFIAFAYSVKSRD	IFITM2	71	Q01629
FFYCSAVTIFFTIIK	PCNX2	61	A6NKB5
FSYGRVKLCSTGFIT	MLH3	596	Q9UHC1
VFIYLRPFCSFSVDK	OR4Q3	256	Q8NH05
KTISFVGCATQYFVF	OR5A2	91	Q8NGI9
FDFKRFLTCGTKLLY	PIK3C2A	796	O00443
YFCVKRIFSGGDQSF	HERC4	361	Q5GLZ8
GLCKVFVSTFYTLTL	GPR153	81	Q6NV75
SSYVFFTKLSGACAL	MFSD2B	416	A6NFX1
FTTIFTRMGKCYTFN	ASIC3	176	Q9UHC3
DSLYFCIVTFSTVGF	KCNT2	231	Q6UVM3
GFLRRYTFNVLFCTS	NPIPB7	66	O75200
TVFLRSYKFAISLCT	NPIPA3	46	F8WFD2
YGVCFVDTSLGKFFI	MSH6	556	P52701
VFLRSYKFAISLCTS	NPIPA2	66	E9PIF3
YGVQFTSSRKFFTIS	ORMDL1	91	Q9P0S3
FSTVLCKLVRFLFYT	P2RY2	101	P41231
FKSKVTRYLCFTRSF	MVB12B	86	Q9H7P6
FKITTRFRTDSGCYA	PTPN21	1026	Q16825
KIGYFIGFSECLSAT	OTOP1	151	Q7RTM1
EKFSIFRYFLRKGCS	ASB3	356	Q9Y575
AGTIFSCTNYFRVIF	CEPT1	256	Q9Y6K0
LIACSGFFYSIFRGR	BCL6B	56	Q8N143
SFVRLGYCSFSKSRI	CARD6	456	Q9BX69
TTGKFSCQVRGIYFF	C1QL2	191	Q7Z5L3
TTGYATCFVFKGLFI	FAM111A	366	Q96PZ2
LRAKCQGYSIFVFSF	COL6A5	2431	A8TX70
FIFASECKTGFRHLY	DPP8	466	Q6V1X1
VFPFRTFYLCAKTGV	DAPP1	231	Q9UN19
CVGFFLFTFTKLYAR	ADCY9	156	O60503
CYFFLSAFVDTAQRK	BLMH	111	Q13867
RYSFLKTASFFVRLG	ALOX12B	201	O75342
FGLYCFVSKTFRATV	GPR142	411	Q7Z601
TKFCFPFYVDSLTVS	DENND1A	51	Q8TEH3
CILRSYGLKTGFFSS	FPGS	116	Q05932
GFCFFNSVAITAKYL	HDAC9	791	Q9UKV0
LFFTSTIYFKCSVLQ	CENPI	481	Q92674
GTFRGTRYFTCALKK	CYLD	516	Q9NQC7
TYRFCSQFSKGVYAI	GRIA1	71	P42261
FGSNYKIITTCFAVS	GRM1	806	Q13255
FYIAVVFTCFIVTTG	CGRRF1	16	Q99675
GIFFYFKSLSCQRIT	CALCRL	161	Q16602
DVCFFFKTTVSSGVF	CNTNAP3B	816	Q96NU0
CVLAAAKAYIFRTFF	PTCHD3	911	Q3KNS1
TAKFIFILCYTANFV	LRRC8D	316	Q7L1W4
DTKIISFSGCFLQFY	OR11G2	126	Q8NGC1
CLGFIAFAYSVKSRD	IFITM1	51	P13164
EKSFICYALFGLFAT	SLC16A6	291	O15403
RKAFSTCGFYLTVVT	OR1L8	236	Q8NGR8
TVFLRSYKFAISLCT	NPIPA7	46	E9PJI5
TVFLRSYKFAISLCT	NPIPA8	46	P0DM63
ASLGFCVTYVFFITS	SLC29A3	306	Q9BZD2
FSRFKDTAYCATFRQ	UTP15	76	Q8TED0
VGKYITTTLFLYFAC	SLC4A11	356	Q8NBS3
FGVFCSSFIAKGVRF	PRDM14	266	Q9GZV8
SKYFFFRICHTIVFT	SLC9C1	596	Q4G0N8
TVFLRSYKFAISLCT	NPIPA5	46	E9PKD4
SAAVFTYCKSRGLFA	SH3YL1	146	Q96HL8
LLFGCSISDYRTFFS	PKD1L3	1611	Q7Z443
SRTKFFIEFYSTCLE	INPPL1	761	O15357
LALFGFVFACYVSKV	NKAIN1	156	Q4KMZ8
CTRISGFLAFKNFDY	PKHD1	3141	P08F94
GKAIFRFSATSALYI	SCN3A	96	Q9NY46
IKIFTLSFCGYNVIS	OR8K3	161	Q8NH51
RGFLIIFSQYLCSFS	PIGW	36	Q7Z7B1
GKAIFRFSATSALYI	SCN1A	96	P35498
LRIGCAFTRFQTKYF	TOP3B	186	O95985
FLLSFLGYCKAFRES	TMTC4	181	Q5T4D3
QKLATCYFFTVEFGL	TPH1	306	P17752
GLFSIIFSFSRKCHY	TMEM269	46	A0A1B0GVZ9
FLCKLSFGYIRSFVT	ZFHX4	281	Q86UP3
FKSFDNRYFTFSGIC	VWF	396	P04275
FSGICYLLSSVSFFF	SLC16A4	461	O15374
SFQVFKFIYSCRLAE	SEC16A	1801	O15027
RAVFSADSKYIFCVS	WDR75	21	Q8IWA0
IFCVSGDFVKVYSTV	WDR75	31	Q8IWA0
AFYGLLSFTAIFCFR	TMEM104	316	Q8NE00
LTSSVYFFVFLGLCT	PIEZO2	241	Q9H5I5
SLKFASCGSYFVTAI	TLE7	376	A0A1W2PR48
QTKRSRGFGFVTYSC	HNRNPA3	71	P51991
LASTRKYFTQFCVKF	VPS53	656	Q5VIR6
VQKLATCYFFTIEFG	TPH2	351	Q8IWU9
GFSFLFFYRGTLCDK	TRDV3	6	A0JD37
FFYRGTLCDKVTQSS	TRDV3	11	A0JD37
CGKFFRYSSTFVRHQ	ZNF548	286	Q8NEK5
FAFFTFCFLSGRAKE	SRD5A1	221	P18405
ILVAGSRFFKTLYCF	ZBTB10	381	Q96DT7
ARAVFGVKCFSYSTS	TMEM70	101	Q9BUB7
ICFTLGSFAKIYADT	EFTUD2	316	Q15029
LFSDGLVRFASCKYS	TTLL4	781	Q14679
LCKLSFGYVRSFVTH	ZFHX3	286	Q15911
ACKAVGSIAYLFFTN	LDLR	391	P01130
FTLFFFCNTATVYKI	LHFPL3	126	Q86UP9