Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoabnormal trigeminal ganglion morphology

RAP1GDS1 ZIC5

5.38e-045592MP:0001092
MousePhenoenlarged lung

ADK RAP1GDS1

5.38e-045592MP:0004882
MousePhenoabnormal phalanx morphology

CTSK HOXA13

1.02e-037692MP:0005306
DomainArm

ARMC3 RAP1GDS1

9.53e-053192PF00514
DomainARM

ARMC3 RAP1GDS1

1.59e-044092SM00185
DomainARM_REPEAT

ARMC3 RAP1GDS1

1.59e-044092PS50176
DomainArmadillo

ARMC3 RAP1GDS1

2.21e-044792IPR000225
Domain-

ARMC3 RAP1GDS1

4.79e-03222921.25.10.10
DomainARM-like

ARMC3 RAP1GDS1

7.01e-0327092IPR011989
DomainHomeodomain-like

LCORL HOXA13

1.04e-0233292IPR009057
DomainARM-type_fold

ARMC3 RAP1GDS1

1.09e-0233992IPR016024
Pubmed

Talin1 and Rap1 are critical for osteoclast function.

TLN1 CTSK

8.92e-0769223230271
Pubmed

A pathogenic CtBP1 missense mutation causes altered cofactor binding and transcriptional activity.

LCORL ZNF516

8.92e-0769231041561
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

TLN1 LCORL HOXA13 ZNF516

1.12e-0411039434189442
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

RAP1GDS1 LCORL ZNF516

1.19e-043989335016035
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

ARMC3 RAP1GDS1

1.15e-044372409
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZIC5 ZNF516

2.90e-027187228
CoexpressionNADLER_OBESITY_UP

TLN1 CTSK

1.84e-046092M1431
CoexpressionBURTON_ADIPOGENESIS_PEAK_AT_0HR

TLN1 CTSK

2.09e-046492M1626
CoexpressionNADLER_OBESITY_UP

TLN1 CTSK

2.29e-046792MM1007
CoexpressionBURTON_ADIPOGENESIS_PEAK_AT_0HR

TLN1 CTSK

2.43e-046992MM1024
CoexpressionGSE36891_POLYIC_TLR3_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_UP

LCORL ZIC5

1.19e-0315392M8789
CoexpressionDESCARTES_FETAL_LIVER_MEGAKARYOCYTES

ARMC3 TLN1

1.31e-0316192M40231
CoexpressionTABULA_MURIS_SENIS_LUNG_ALVEOLAR_MACROPHAGE_AGEING

TLN1 CTSK

1.75e-0318692MM3762
CoexpressionP53_DN.V1_DN

CTSK ZNF516

1.90e-0319492M2697
CoexpressionGSE43863_NAIVE_VS_TH1_EFF_CD4_TCELL_D6_LCMV_UP

TLN1 ZNF516

1.90e-0319492M9723
CoexpressionGSE43863_NAIVE_VS_LY6C_INT_CXCR5POS_CD4_EFF_TCELL_D6_LCMV_UP

ADK ZNF516

1.95e-0319792M9730
CoexpressionGSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_DN

RAP1GDS1 LCORL

1.99e-0319992M7479
CoexpressionGSE11924_TH1_VS_TH2_CD4_TCELL_DN

ADK CTSK

1.99e-0319992M3160
CoexpressionGSE35435_RESTING_VS_IL4_TREATED_MACROPHAGE_DN

ADK ZNF516

1.99e-0319992M9543
CoexpressionGSE36888_UNTREATED_VS_IL2_TREATED_TCELL_6H_DN

ADK RAP1GDS1

1.99e-0319992M8741
CoexpressionGSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_DN

RAP1GDS1 CTSK

1.99e-0319992M5268
CoexpressionGSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY3_UP

ARMC3 ADK

1.99e-0319992M6581
CoexpressionGSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_DN

RAP1GDS1 CTSK

1.99e-0319992M3486
CoexpressionGSE17721_POLYIC_VS_CPG_12H_BMDC_DN

RAP1GDS1 HOXA13

2.01e-0320092M3949
CoexpressionGSE27786_NKCELL_VS_NEUTROPHIL_DN

ARMC3 ZNF516

2.01e-0320092M4859
CoexpressionGSE4142_PLASMA_CELL_VS_GC_BCELL_UP

CTSK ZNF516

2.01e-0320092M6390
CoexpressionGSE19923_E2A_KO_VS_E2A_AND_HEB_KO_DP_THYMOCYTE_UP

ADK RAP1GDS1

2.01e-0320092M7275
CoexpressionGSE5589_WT_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN

ARMC3 TLN1

2.01e-0320092M6650
CoexpressionGSE5589_IL6_KO_VS_IL10_KO_LPS_STIM_MACROPHAGE_180MIN_UP

ARMC3 TLN1

2.01e-0320092M6664
CoexpressionGSE39152_BRAIN_VS_SPLEEN_CD103_NEG_MEMORY_CD8_TCELL_UP

ADK RAP1GDS1

2.01e-0320092M9075
CoexpressionGSE27786_NKTCELL_VS_NEUTROPHIL_DN

ARMC3 ZNF516

2.01e-0320092M4869
CoexpressionGSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_3H_UP

ADK LCORL

2.01e-0320092M8279
CoexpressionGSE24726_WT_VS_E2_2_KO_PDC_DN

RAP1GDS1 CTSK

2.01e-0320092M8061
CoexpressionGSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP

ADK LCORL

2.01e-0320092M6029
CoexpressionGSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN

ADK TLN1

2.01e-0320092M8485
CoexpressionGSE19401_UNSTIM_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_UP

RAP1GDS1 CTSK

2.01e-0320092M7665
CoexpressionGSE9650_GP33_VS_GP276_LCMV_SPECIFIC_EXHAUSTED_CD8_TCELL_UP

TLN1 CTSK

2.01e-0320092M5842
CoexpressionGSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_DN

ADK RAP1GDS1

2.01e-0320092M3429
CoexpressionGSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN

CTSK ZNF516

2.01e-0320092M3469
CoexpressionGSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP

ADK TLN1

2.01e-0320092M6514
CoexpressionDESCARTES_FETAL_PLACENTA_MEGAKARYOCYTES

ARMC3 TLN1

2.07e-0320392M40286
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet-plt_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ARMC3 TLN1

4.51e-0416192bfb79277889142133ce86492a808f3083a7547e8
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet-plt_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARMC3 TLN1

4.51e-0416192d6f4b0e4e3b2a4e6232a6de3d67b210e24f8c89d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CD24|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARMC3 LCORL

5.26e-04174923e29d620b7b4ab1915ddac70ee5a50d09072292b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCORL ZNF516

5.69e-0418192ad30c01290fb98adbd0caed301a584761212c977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCORL ZNF516

5.69e-04181923a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCORL ZNF516

5.69e-04181924e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-9|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

ADK RAP1GDS1

6.07e-0418792f002ff1a7cb7577f28acff008bc2aa561ac1a4bf
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADK RAP1GDS1

6.13e-041889243a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCellCOVID-19_Moderate-Platelet|World / disease group, cell group and cell class

ARMC3 TLN1

6.26e-04190926e4f4af5ba185bb022753881a26a269a544bb59b
ToppCelldroplet-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADK CTSK

6.46e-04193922d891c00b8f0aace17d4c300b63e2341dcffa199
ToppCelldroplet-Bladder-nan-3m-Epithelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADK CTSK

6.53e-0419492b294056f9bdc243263cf36dce7b62564144b9de1
ToppCellfacs-GAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADK CTSK

6.53e-041949293b7a9065430740ec31fce4e8c14ffccb498591d
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CTSK HOXA13

6.53e-041949269362e13158033de44f90f3773db6c0f27de8cb3
ToppCellfacs-GAT-Fat-18m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADK CTSK

6.53e-04194920d2e65b44e3f143971c2fd24c4552f042b049cfa
ToppCellfacs-GAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADK CTSK

6.53e-04194929709dc95fb6982b6a0467b507845d5bc17252e3e
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ADK CTSK

6.59e-041959278978d85273e5463a7f43e4c121e647fa6aba42b
ToppCellfacs-Bladder-nan-18m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADK CTSK

6.59e-04195923e4f9ecfaa756386d816a26313b7229ec092d4e6
ToppCelldroplet-Bladder-nan-3m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADK CTSK

6.66e-0419692f47e551ba484687ba6ce8c29a085106131364042
ToppCellKidney-Mesangial|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.

TLN1 ZIC5

6.66e-04196922b2cbe7f96213b7ff50442593f31820d17a2ae94
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADK CTSK

6.73e-0419792036c4c9b3ae80e2dc21c24a84504d3da0541f945
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADK CTSK

6.73e-0419792cfd4cc5fb8d7a60dd5c0d2a1a7bad7ba38c19d40
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADK CTSK

6.80e-04198928f202ed4692ea2c139ff05d4805c704ee4be095c
ToppCelldistal-mesenchymal-Myofibroblast-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CTSK ZIC5

6.80e-0419892beef5075ba6dcd4d0a447bc4e57efcaf2e93c546
ToppCelldroplet-Trachea-nan-3m-Mesenchymal-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADK CTSK

6.80e-0419892d3a475be01657a03fcbb0ee0a246b1e90deacaa4
ToppCelldroplet-Trachea-nan-3m-Mesenchymal|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADK CTSK

6.80e-0419892985022c1722ab7b67675ebe814022a439e715b5e
ToppCelldroplet-Trachea-3m-Mesenchymal|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADK CTSK

6.80e-04198921beed34f469aad07e8f674f0b668d6e1e916403c
ToppCelldistal-2-mesenchymal-Myofibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CTSK ZIC5

6.87e-0419992b8f3cf5bcfde1066bdb49b14fdc842fe9692a6b7
ToppCellfacs-Trachea-nan-3m-Mesenchymal|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADK CTSK

6.87e-041999267f78c070c56e44fba36542041bf7fa1c291807c
ToppCellfacs-Trachea-nan-3m-Mesenchymal-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADK CTSK

6.87e-04199921ae244b563f85c1ee8d22698f478c842a4d9c7f5
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-BMP_responsible_cell|6m / Sample Type, Dataset, Time_group, and Cell type.

ARMC3 ZIC5

6.93e-04200925fb90118d3abc28d72bc483e68317255090a04c7
DrugAC1NDVEB

ADK HOXA13

5.59e-049192CID004632235
DrugEtoposide [33419-42-0]; Down 200; 6.8uM; HL60; HG-U133A

ADK ZNF516

2.16e-03180921626_DN
DrugDextroamphetamine

TLN1 CTSK

2.28e-0318592ctd:D003913
DrugLycorine hydrochloride [2188-68-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A

CTSK ZNF516

2.28e-03185924365_DN
DrugCloperastine hydrochloride [14984-68-0]; Up 200; 11uM; PC3; HT_HG-U133A

TLN1 ZNF516

2.30e-03186924271_UP
Diseaseblood urea nitrogen measurement

ADK LCORL HOXA13

2.80e-0445293EFO_0004741
Diseasediverticular disease

ADK LCORL

2.21e-0323692EFO_0009959
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

LCORL HOXA13

5.16e-0336492EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
DiseaseS-6-hydroxywarfarin measurement

ARMC3 LCORL

5.27e-0336892EFO_0803326
Diseaseneutrophil count

ARMC3 CTSK ZNF516

6.96e-03138293EFO_0004833
Diseasecorneal resistance factor

LCORL ZNF516

7.82e-0345192EFO_0010067
Diseasecardiovascular disease

ADK LCORL

8.02e-0345792EFO_0000319
Diseaselymphocyte count

ADK TLN1 LCORL

8.17e-03146493EFO_0004587
Diseasefacial morphology measurement

ADK LCORL

8.33e-0346692EFO_0007841
Diseasebody fat percentage

LCORL HOXA13

9.10e-0348892EFO_0007800
DiseaseLiver carcinoma

ZIC5 HOXA13

9.79e-0350792C2239176
Diseasediastolic blood pressure, systolic blood pressure

ADK ZIC5

1.67e-0267092EFO_0006335, EFO_0006336
DiseaseAbnormality of refraction

LCORL ZNF516

1.68e-0267392HP_0000539
Diseaseplatelet component distribution width

ARMC3 TLN1

2.09e-0275592EFO_0007984

Protein segments in the cluster

PeptideGeneStartEntry
ARNKNNACGIANLAS

CTSK

311

P43235
GDNRSLIANLAAANC

ADK

146

P55263
ANLTTCNPANANAAA

ARMC3

381

Q5W041
AAAAAAAAAAAAQCR

LCORL

11

Q8N3X6
GALAIANFARNDANC

RAP1GDS1

336

P52306
AAAAAAAAANQCRNL

HOXA13

76

P31271
ASACNRLLNGASQAD

ZNF516

121

Q92618
AAATNNLCEAANAAV

TLN1

2401

Q9Y490
NLNLNLAAAAAAAAA

ZIC5

331

Q96T25