Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transporter activity	ATP6V1B1 SLC22A25 ABCA3 SLC52A1 LRRC38 SLC43A1 TMC4 PKD1L2 PKDREJ KCNK7 ATP10A ABCA7 ABCC6 PANX3 SLC2A5 CALHM2 CHRNE SLC2A10 SLC22A18 SLC7A4 CACNG8 MFSD14B SLC22A16 SLCO2A1 GLRB TMEM38A TRPV3 SLC25A29 SLC4A4 LMBRD1 MFSD10 SLC35A5	1.03e-07	1289	177	32	GO:0005215
GeneOntologyMolecularFunction	transmembrane transporter activity	ATP6V1B1 SLC22A25 ABCA3 SLC52A1 LRRC38 SLC43A1 TMC4 PKD1L2 PKDREJ KCNK7 ABCA7 ABCC6 PANX3 SLC2A5 CALHM2 CHRNE SLC2A10 SLC22A18 SLC7A4 CACNG8 MFSD14B SLC22A16 SLCO2A1 GLRB TMEM38A TRPV3 SLC25A29 SLC4A4 MFSD10 SLC35A5	1.65e-07	1180	177	30	GO:0022857
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	GPR6 CYSLTR2 LPAR5 PDGFRA ADGRB2 C5AR2 ADGRG1 ABCA7 OPRD1 CHRNE NLRP6 ADRA1B ADRA1A ADGRG2 GPR142 GPR149 IL21R GLRB RXFP2 TNF TAS2R40 FGFR2 FCRL4 ACKR1 PLXNA2 GPR151 GP1BA	6.10e-05	1353	177	27	GO:0004888
GeneOntologyMolecularFunction	ATP-dependent activity	DNHD1 ATP6V1B1 ABCA3 MYO7B RHOBTB3 RNF213 MSH2 ATP10A ABCA7 ABCC6 ACSL1 MDN1 STARD9 DNA2 DNAH5 DNAH11	1.19e-04	614	177	16	GO:0140657
GeneOntologyMolecularFunction	alpha1-adrenergic receptor activity	ADRA1B ADRA1A	2.33e-04	3	177	2	GO:0004937
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNHD1 SPTBN5 DNAH5 DNAH11	3.14e-04	37	177	4	GO:0045505
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNHD1 DNAH5 DNAH11	5.07e-04	18	177	3	GO:0008569
GeneOntologyCellularComponent	apical part of cell	ATP6V1B1 PDE4D ANK2 MYO7B SLC43A1 C5AR2 ABCA7 ABCC6 SLC2A5 SPTBN5 SLC22A18 ADGRG2 DCHS1 SCRIB LRRC15 NLRP5	4.91e-05	592	178	16	GO:0045177
GeneOntologyCellularComponent	sarcolemma	ANK2 OBSCN SLC2A5 BGN ADRA1B CACNG8 ADRA1A PLCB3	2.30e-04	190	178	8	GO:0042383
Domain	-	LRRC38 PRAMEF20 BGN NLRP6 LRRIQ1 CIITA RXFP2 NLRC5 SCRIB NLRC3 LRRC15 PHLPP2 GP1BA NLRP5	1.83e-06	321	173	14	3.80.10.10
Domain	NACHT	NLRP6 CIITA NLRC5 NLRC3 NLRP5	1.89e-06	23	173	5	PS50837
Domain	NACHT_NTPase	NLRP6 CIITA NLRC5 NLRC3 NLRP5	1.89e-06	23	173	5	IPR007111
Domain	L_dom-like	LRRC38 PRAMEF20 BGN NLRP6 LRRIQ1 CIITA RXFP2 NLRC5 SCRIB NLRC3 LRRC15 PHLPP2 GP1BA NLRP5	2.35e-06	328	173	14	IPR032675
Domain	MFS_dom	SLC22A25 SLC43A1 SLC2A5 SLC2A10 SLC22A18 MFSD14B SLC22A16 SLCO2A1 MFSD10	4.41e-06	134	173	9	IPR020846
Domain	MFS	SLC22A25 SLC2A5 SLC2A10 SLC22A18 MFSD14B SLC22A16 SLCO2A1 MFSD10	7.38e-06	108	173	8	PS50850
Domain	Leu-rich_rpt	LRRC38 BGN LRRIQ1 CIITA RXFP2 NLRC5 SCRIB NLRC3 LRRC15 PHLPP2 GP1BA NLRP5	8.75e-06	271	173	12	IPR001611
Domain	GPS	ADGRB2 ADGRG1 PKD1L2 PKDREJ ADGRG2	1.44e-05	34	173	5	SM00303
Domain	LRR	LRRC38 BGN LRRIQ1 CIITA RXFP2 NLRC5 SCRIB LRRC15 PHLPP2 GP1BA	1.85e-05	201	173	10	PS51450
Domain	GPS	ADGRB2 ADGRG1 PKD1L2 PKDREJ ADGRG2	2.21e-05	37	173	5	IPR000203
Domain	P-loop_NTPase	DNHD1 ATP6V1B1 ABCA3 MYO7B RHOBTB3 RNF213 MSH2 ABCA7 ABCC6 NLRP6 MDN1 LRRIQ1 CIITA STARD9 NLRC5 COASY DNA2 DNAH5 DNAH11 NLRP5	1.19e-04	848	173	20	IPR027417
Domain	LRR_1	LRRC38 BGN LRRIQ1 CIITA RXFP2 NLRC5 SCRIB LRRC15 PHLPP2	2.09e-04	219	173	9	PF00560
Domain	LRR_TYP	LRRC38 BGN LRRIQ1 RXFP2 SCRIB LRRC15 PHLPP2 GP1BA	2.49e-04	177	173	8	SM00369
Domain	Leu-rich_rpt_typical-subtyp	LRRC38 BGN LRRIQ1 RXFP2 SCRIB LRRC15 PHLPP2 GP1BA	2.49e-04	177	173	8	IPR003591
Domain	Dynein_HC_stalk	DNHD1 DNAH5 DNAH11	2.64e-04	14	173	3	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DNAH5 DNAH11	2.64e-04	14	173	3	IPR013602
Domain	DHC_N2	DNHD1 DNAH5 DNAH11	2.64e-04	14	173	3	PF08393
Domain	ATPase_dyneun-rel_AAA	MDN1 DNAH5 DNAH11	2.64e-04	14	173	3	IPR011704
Domain	MT	DNHD1 DNAH5 DNAH11	2.64e-04	14	173	3	PF12777
Domain	AAA_5	MDN1 DNAH5 DNAH11	2.64e-04	14	173	3	PF07728
Domain	GPS	ADGRB2 ADGRG1 PKD1L2 ADGRG2	2.97e-04	35	173	4	PF01825
Domain	DHC_fam	DNHD1 DNAH5 DNAH11	3.27e-04	15	173	3	IPR026983
Domain	Dynein_heavy	DNHD1 DNAH5 DNAH11	3.27e-04	15	173	3	PF03028
Domain	Dynein_heavy_dom	DNHD1 DNAH5 DNAH11	3.27e-04	15	173	3	IPR004273
Domain	ARM-type_fold	CIP2A INTS1 IPO4 MEI1 FOCAD THADA TELO2 ARMC5 ULK4 MMS19 TNPO3	3.31e-04	339	173	11	IPR016024
Domain	GPS	ADGRB2 ADGRG1 PKD1L2 ADGRG2	3.32e-04	36	173	4	PS50221
Domain	AAA	ABCA3 RNF213 ABCA7 ABCC6 MDN1 DNAH5 DNAH11	3.93e-04	144	173	7	SM00382
Domain	AAA+_ATPase	ABCA3 RNF213 ABCA7 ABCC6 MDN1 DNAH5 DNAH11	3.93e-04	144	173	7	IPR003593
Domain	RetinoicA-induced_16-like	FHIP1B FHIP1A	5.06e-04	4	173	2	IPR019384
Domain	RAI16-like	FHIP1B FHIP1A	5.06e-04	4	173	2	PF10257
Domain	GPR1/GPR3/GPR5	ADGRG1 ADGRG2	5.06e-04	4	173	2	IPR003910
Domain	REJ	PKD1L2 PKDREJ	5.06e-04	4	173	2	PS51111
Domain	REJ_dom	PKD1L2 PKDREJ	5.06e-04	4	173	2	IPR014010
Domain	MFS_1	SLC22A25 SLC43A1 SLC22A18 MFSD14B MFSD10	7.42e-04	77	173	5	PF07690
Domain	MFS	SLC22A25 SLC43A1 SLC22A18 MFSD14B MFSD10	7.42e-04	77	173	5	IPR011701
Domain	Anaphylatoxin_comp_syst	C4A C4B	8.38e-04	5	173	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	8.38e-04	5	173	2	IPR001840
Domain	PKD_2	PKD1L2 PKDREJ	8.38e-04	5	173	2	IPR003915
Domain	Tet-R_TetA/multi-R_MdtG	SLC22A18 MFSD14B	8.38e-04	5	173	2	IPR001958
Domain	ARM-like	CIP2A IPO4 MEI1 TELO2 AP5Z1 ARMC5 ULK4 MMS19 TNPO3	9.52e-04	270	173	9	IPR011989
Domain	LRR_8	LRRC38 BGN RXFP2 SCRIB LRRC15 PHLPP2 GP1BA	1.09e-03	171	173	7	PF13855
Domain	-	CIP2A IPO4 TELO2 AP5Z1 ARMC5 ULK4 MMS19 TNPO3	1.11e-03	222	173	8	1.25.10.10
Domain	PKD/REJ-like	PKD1L2 PKDREJ	1.25e-03	6	173	2	IPR002859
Domain	REJ	PKD1L2 PKDREJ	1.25e-03	6	173	2	PF02010
Domain	SUGAR_TRANSPORT_1	SLC2A5 SLC2A10 MFSD14B	1.37e-03	24	173	3	PS00216
Domain	LRR_6	CIITA NLRC5 NLRC3 NLRP5	1.68e-03	55	173	4	PF13516
Domain	ANATO	C4A C4B	1.74e-03	7	173	2	SM00104
Domain	ANAPHYLATOXIN_2	C4A C4B	1.74e-03	7	173	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	1.74e-03	7	173	2	PS01177
Domain	ANATO	C4A C4B	1.74e-03	7	173	2	PF01821
Domain	Anaphylatoxin/fibulin	C4A C4B	1.74e-03	7	173	2	IPR000020
Domain	LRRNT	LRRC38 BGN RXFP2 LRRC15 GP1BA	2.18e-03	98	173	5	IPR000372
Domain	LRRNT	LRRC38 BGN RXFP2 LRRC15 GP1BA	2.18e-03	98	173	5	SM00013
Domain	DHC_N1	DNAH5 DNAH11	2.30e-03	8	173	2	PF08385
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	2.30e-03	8	173	2	IPR019565
Domain	Thiol-ester_cl	C4A C4B	2.30e-03	8	173	2	PF10569
Domain	MacrogloblnA2_CS	C4A C4B	2.30e-03	8	173	2	IPR019742
Domain	Dynein_heavy_dom-1	DNAH5 DNAH11	2.30e-03	8	173	2	IPR013594
Domain	Sugar_transporter_CS	SLC2A5 SLC2A10 MFSD14B	3.18e-03	32	173	3	IPR005829
Domain	A2M	C4A C4B	3.66e-03	10	173	2	PF00207
Domain	A2M_N_2	C4A C4B	3.66e-03	10	173	2	IPR011625
Domain	A2M_comp	C4A C4B	3.66e-03	10	173	2	IPR011626
Domain	A2M_recep	C4A C4B	3.66e-03	10	173	2	PF07677
Domain	A2M_comp	C4A C4B	3.66e-03	10	173	2	PF07678
Domain	A2M_N	C4A C4B	3.66e-03	10	173	2	PF01835
Domain	A2M_N	C4A C4B	3.66e-03	10	173	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B	3.66e-03	10	173	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B	3.66e-03	10	173	2	PS00477
Domain	A2M_N_2	C4A C4B	3.66e-03	10	173	2	PF07703
Domain	ADR_fam	ADRA1B ADRA1A	3.66e-03	10	173	2	IPR002233
Domain	Macroglobln_a2	C4A C4B	3.66e-03	10	173	2	IPR001599
Domain	-	DNHD1 ATP6V1B1 ABCA3 MYO7B RHOBTB3 RNF213 MSH2 ABCA7 ABCC6 MDN1 NLRC5 COASY DNA2 DNAH5 DNAH11	4.04e-03	746	173	15	3.40.50.300
Domain	PKD_channel	PKD1L2 PKDREJ	4.44e-03	11	173	2	PF08016
Domain	Laminin_G_1	HSPG2 EYS	4.44e-03	11	173	2	PF00054
Domain	PKD1_2_channel	PKD1L2 PKDREJ	4.44e-03	11	173	2	IPR013122
Domain	MFS_sugar_transport-like	SLC2A5 SLC2A10 SLC22A16	4.46e-03	36	173	3	IPR005828
Domain	Sugar_tr	SLC2A5 SLC2A10 SLC22A16	4.46e-03	36	173	3	PF00083
Domain	ABC_A	ABCA3 ABCA7	5.30e-03	12	173	2	IPR026082
Domain	ZU5	ANK2 SH3BP4	5.30e-03	12	173	2	PF00791
Domain	ZU5_dom	ANK2 SH3BP4	5.30e-03	12	173	2	IPR000906
Domain	SSD	HMGCR PTCHD1	6.22e-03	13	173	2	IPR000731
Domain	SSD	HMGCR PTCHD1	6.22e-03	13	173	2	PS50156
Domain	ABC_transporter_CS	ABCA3 ABCA7 ABCC6	6.88e-03	42	173	3	IPR017871
Domain	Dynein_heavy_chain_D4_dom	DNAH5 DNAH11	7.22e-03	14	173	2	IPR024317
Domain	Myotubularin-like_Pase_dom	MTMR11 SBF1	7.22e-03	14	173	2	IPR010569
Domain	Sugar/inositol_transpt	SLC2A5 SLC2A10	7.22e-03	14	173	2	IPR003663
Domain	AAA_8	DNAH5 DNAH11	7.22e-03	14	173	2	PF12780
Domain	PPASE_MYOTUBULARIN	MTMR11 SBF1	7.22e-03	14	173	2	PS51339
Domain	Myotubularin_fam	MTMR11 SBF1	7.22e-03	14	173	2	IPR030564
Domain	Myotub-related	MTMR11 SBF1	7.22e-03	14	173	2	PF06602
Pathway	WP_GPCRS_NONODORANT	GPR6 CYSLTR2 LPAR5 ADGRB2 C5AR2 ADGRG1 OPRD1 ADRA1B ADRA1A ADGRG2 RXFP2 TAS2R40 ACKR1	4.59e-07	266	121	13	MM15843
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HSPG2 ARID3A MAN2B1 LPAR5 PCNX3 SZT2 INTS1 OBSCN ADGRB2 FHIP1B ABCA7 SH3BP4 FOCAD THADA MDN1 SBF1 NLRC5 ULK4 WDR90 TANC1 FGFR2 SNAPC4 TNPO3	1.81e-08	1105	181	23	35748872
Pubmed	A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3.	C4A C4B GP1BA	4.78e-06	7	181	3	22037602
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	LPAR5 INTS1 OBSCN RNF213 PBX4 USP20 FOCAD ADRA1A MDN1 SLC22A16 AGL PLCB3 SCRIB HBZ GP1BA	8.01e-06	736	181	15	29676528
Pubmed	Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.	VWA7 NEU1 C4A C4B TNF	1.02e-05	55	181	5	14656967
Pubmed	HLA-association of serum levels of natural antibodies.	C4A C4B TNF	1.62e-05	10	181	3	19167759
Pubmed	Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling.	C5AR2 C4A C4B	1.62e-05	10	181	3	30429287
Pubmed	Pdgfrα functions in endothelial-derived cells to regulate neural crest cells and the development of the great arteries.	HSPG2 PDGFRA PLXNA2	2.22e-05	11	181	3	28714851
Pubmed	FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA.	CIITA NLRC5 MMS19	2.22e-05	11	181	3	37279268
Pubmed	The mouse as a model for the effects of MHC genes on human disease.	VWA7 NEU1 C4A C4B TNF	2.69e-05	67	181	5	10871872
Pubmed	An alpha1A-adrenergic-extracellular signal-regulated kinase survival signaling pathway in cardiac myocytes.	ADRA1B ADRA1A	2.69e-05	2	181	2	17283256
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	2.69e-05	2	181	2	19062096
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	2.69e-05	2	181	2	17645767
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	2.69e-05	2	181	2	12207352
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	2.69e-05	2	181	2	27758680
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	2.69e-05	2	181	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	2.69e-05	2	181	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	2.69e-05	2	181	2	4216347
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	2.69e-05	2	181	2	8428773
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	2.69e-05	2	181	2	24638111
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	2.69e-05	2	181	2	21345967
Pubmed	The complement component C4 of mammals.	C4A C4B	2.69e-05	2	181	2	2302180
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	2.69e-05	2	181	2	22151770
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	2.69e-05	2	181	2	29080553
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	2.69e-05	2	181	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	2.69e-05	2	181	2	17728371
Pubmed	Structure and organization of the C4 genes.	C4A C4B	2.69e-05	2	181	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	2.69e-05	2	181	2	6149581
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	2.69e-05	2	181	2	3542363
Pubmed	LXRα Regulates ChREBPα Transactivity in a Target Gene-Specific Manner through an Agonist-Modulated LBD-LID Interaction.	NR1H3 MLXIPL	2.69e-05	2	181	2	32414201
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	2.69e-05	2	181	2	2387317
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	2.69e-05	2	181	2	7365238
Pubmed	Rare variants in dynein heavy chain genes in two individuals with situs inversus and developmental dyslexia: a case report.	DNAH5 DNAH11	2.69e-05	2	181	2	32357925
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	2.69e-05	2	181	2	17971360
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	2.69e-05	2	181	2	17971229
Pubmed	Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.	C4A C4B	2.69e-05	2	181	2	35898513
Pubmed	Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.	C4A C4B	2.69e-05	2	181	2	28873507
Pubmed	Nuclear alpha1-adrenergic receptors signal activated ERK localization to caveolae in adult cardiac myocytes.	ADRA1B ADRA1A	2.69e-05	2	181	2	18802028
Pubmed	Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.	C4A C4B	2.69e-05	2	181	2	3794341
Pubmed	Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.	C4A C4B	2.69e-05	2	181	2	22785613
Pubmed	Carbohydrate-response-element-binding protein (ChREBP) and not the liver X receptor α (LXRα) mediates elevated hepatic lipogenic gene expression in a mouse model of glycogen storage disease type 1.	NR1H3 MLXIPL	2.69e-05	2	181	2	20854262
Pubmed	Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.	C4A C4B	2.69e-05	2	181	2	32691186
Pubmed	The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.	C4A C4B	2.69e-05	2	181	2	8390682
Pubmed	Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).	C4A C4B	2.69e-05	2	181	2	3902619
Pubmed	Alpha1-adrenergic receptors prevent a maladaptive cardiac response to pressure overload.	ADRA1B ADRA1A	2.69e-05	2	181	2	16585965
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	2.69e-05	2	181	2	7373044
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	2.69e-05	2	181	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	2.69e-05	2	181	2	16098595
Pubmed	Oligomerization of the alpha 1a- and alpha 1b-adrenergic receptor subtypes. Potential implications in receptor internalization.	ADRA1B ADRA1A	2.69e-05	2	181	2	12888550
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	2.69e-05	2	181	2	15787745
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	2.69e-05	2	181	2	30026462
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	2.69e-05	2	181	2	6559257
Pubmed	NLR family member NLRC5 is a transcriptional regulator of MHC class I genes.	CIITA NLRC5	2.69e-05	2	181	2	20639463
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	2.69e-05	2	181	2	12480675
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	2.69e-05	2	181	2	26800705
Pubmed	Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.	C4A C4B	2.69e-05	2	181	2	1699796
Pubmed	Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.	C4A C4B	2.69e-05	2	181	2	2997024
Pubmed	Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.	C4A C4B	2.69e-05	2	181	2	3624865
Pubmed	Identification of the fructose transporter GLUT5 (SLC2A5) as a novel target of nuclear receptor LXR.	NR1H3 SLC2A5	2.69e-05	2	181	2	31243309
Pubmed	Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.	C4A C4B	2.69e-05	2	181	2	30041577
Pubmed	Complete cDNA sequence of the fourth component of murine complement.	C4A C4B	2.69e-05	2	181	2	3862104
Pubmed	Schizophrenia risk from complex variation of complement component 4.	C4A C4B	2.69e-05	2	181	2	26814963
Pubmed	Tumor necrosis factor α induces α1B-adrenergic receptor expression in keratinocytes.	ADRA1B TNF	2.69e-05	2	181	2	31520851
Pubmed	Promoter elements of the mouse complement C4 gene critical for transcription activation and start site location.	C4A C4B	2.69e-05	2	181	2	8132550
Pubmed	Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.	C4A C4B	2.69e-05	2	181	2	2395880
Pubmed	Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations.	C4A C4B	2.69e-05	2	181	2	26814708
Pubmed	Slp is an essential component of an EDTA-resistant activation pathway of mouse complement.	C4A C4B	2.69e-05	2	181	2	1438267
Pubmed	Genetic deficiency of complement isoforms C4A or C4B predicts improved survival of metastatic renal cell carcinoma.	C4A C4B	2.69e-05	2	181	2	19150565
Pubmed	{alpha}1-Adrenergic receptor subtypes in nonfailing and failing human myocardium.	ADRA1B ADRA1A	2.69e-05	2	181	2	19919991
Pubmed	Elevated levels of endogenous apoptotic DNA and IFN-alpha in complement C4-deficient mice: implications for induction of systemic lupus erythematosus.	C4A C4B	2.69e-05	2	181	2	17506029
Pubmed	Low C4 gene copy numbers are associated with superior graft survival in patients transplanted with a deceased donor kidney.	C4A C4B	2.69e-05	2	181	2	23715124
Pubmed	Complete nucleotide and derived amino acid sequences of the fourth component of mouse complement (C4). Evolutionary aspects.	C4A C4B	2.69e-05	2	181	2	2993295
Pubmed	Regulation of class I major histocompatibility complex (MHC) by nucleotide-binding domain, leucine-rich repeat-containing (NLR) proteins.	CIITA NLRC5	2.69e-05	2	181	2	22645137
Pubmed	Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice.	C4A C4B	2.69e-05	2	181	2	33353966
Pubmed	Heterogeneity and linkage of equine C4 and steroid 21-hydroxylase genes.	C4A C4B	2.69e-05	2	181	2	2900855
Pubmed	Differences in the signaling pathways of α(1A)- and α(1B)-adrenoceptors are related to different endosomal targeting.	ADRA1B ADRA1A	2.69e-05	2	181	2	23717684
Pubmed	Abnormal myocardial contraction in alpha(1A)- and alpha(1B)-adrenoceptor double-knockout mice.	ADRA1B ADRA1A	2.69e-05	2	181	2	14519431
Pubmed	Genetic deficiency in complement component 4b does not alter radiation-induced lung disease in mice.	C4A C4B	2.69e-05	2	181	2	23259761
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	2.69e-05	2	181	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	2.69e-05	2	181	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	2.69e-05	2	181	2	15998580
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	2.69e-05	2	181	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	2.69e-05	2	181	2	2459207
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	2.69e-05	2	181	2	22387014
Pubmed	NLRC5-CIITA Fusion Protein as an Effective Inducer of MHC-I Expression and Antitumor Immunity.	CIITA NLRC5	2.69e-05	2	181	2	37108368
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	2.69e-05	2	181	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	2.69e-05	2	181	2	23918728
Pubmed	Expression of proteoglycans in two types of ameloblastoma: novel Immunohistochemical findings.	HSPG2 BGN	2.69e-05	2	181	2	29921372
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	2.69e-05	2	181	2	6950384
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	2.69e-05	2	181	2	8660986
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	2.69e-05	2	181	2	2572548
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	2.69e-05	2	181	2	18091514
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	2.69e-05	2	181	2	6589636
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	2.69e-05	2	181	2	12115608
Pubmed	The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule.	HSPG2 RHOBTB3	2.69e-05	2	181	2	1744087
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	2.69e-05	2	181	2	16908004
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	2.69e-05	2	181	2	7391573
Pubmed	Clinical features of patients with homozygous complement C4A or C4B deficiency.	C4A C4B	2.69e-05	2	181	2	29928053
Pubmed	Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.	C4A C4B	2.69e-05	2	181	2	6881182
Pubmed	Cutting edge: impaired MHC class I expression in mice deficient for Nlrc5/class I transactivator.	CIITA NLRC5	2.69e-05	2	181	2	22711889
Pubmed	Partial C4 deficiency in juvenile idiopathic arthritis patients.	C4A C4B	2.69e-05	2	181	2	17921792
Interaction	TMEM130 interactions	ABCA3 RHOBTB3 INTS1 SLC2A5 TMEM131 FGFR2 TNPO3	2.32e-08	36	176	7	int:TMEM130
Interaction	GPR182 interactions	CIP2A RHOBTB3 INTS1 ADGRG1 RNF213 PPOX FOCAD ACSL1 THADA MDN1 TELO2 AP5Z1 CCDC138 MMS19 SLC25A29 HSD17B11 TNPO3	5.37e-07	455	176	17	int:GPR182
Interaction	SCN2B interactions	CIP2A RNF213 IPO4 FOCAD THADA MDN1 C4A TNPO3	1.84e-06	95	176	8	int:SCN2B
Interaction	NPTN interactions	CIP2A INTS1 RNF213 IPO4 FOCAD THADA MDN1 TELO2 AP5Z1 MMS19 SLC25A29 TNPO3	6.33e-06	278	176	12	int:NPTN
Interaction	OPALIN interactions	CIP2A RHOBTB3 DOLK INTS1 RNF213 THADA MDN1 SBF1 TELO2 TNPO3	1.58e-05	209	176	10	int:OPALIN
Cytoband	17p13.2	SLC52A1 GGT6 CHRNE TRPV3	6.81e-05	55	181	4	17p13.2
GeneFamily	NLR family	NLRP6 CIITA NLRC5 NLRC3 NLRP5	7.21e-07	25	126	5	666
GeneFamily	Solute carriers	SLC22A25 SLC52A1 SLC43A1 SLC2A5 SLC2A10 SLC22A18 SLC7A4 SLC22A16 SLCO2A1 SLC25A29 SLC4A4 SLC35A5	2.07e-05	395	126	12	752
GeneFamily	Adhesion G protein-coupled receptors, subfamily G	ADGRG1 ADGRG2	9.89e-04	7	126	2	917
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	1.68e-03	9	126	2	1234
GeneFamily	Adrenoceptors	ADRA1B ADRA1A	1.68e-03	9	126	2	169
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ICOSLG PDGFRA CDCP1 CD7 IL21R FGFR2 FCRL4 ACKR1 GP1BA	1.77e-03	394	126	9	471
GeneFamily	G protein-coupled receptors, Class A orphans	GPR6 GPR142 GPR149 GPR151	2.15e-03	78	126	4	262
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	C4A C4B ACKR1	2.16e-03	37	126	3	454
GeneFamily	ATP binding cassette subfamily A	ABCA3 ABCA7	4.15e-03	14	126	2	805
Coexpression	MILI_PSEUDOPODIA_CHEMOTAXIS_DN	ABCA3 MAN2B1 PCNX3 PDGFRA DOLK HMGCR ATP10A ABCA7 SLC2A10 NEU1 MFSD14B SLCO2A1 LMBRD1 MFSD10	3.87e-06	457	181	14	M1613
Coexpression	MILI_PSEUDOPODIA_CHEMOTAXIS_DN	ABCA3 MAN2B1 PCNX3 PDGFRA DOLK HMGCR ATP10A ABCA7 SLC2A10 NEU1 MFSD14B SLCO2A1 LMBRD1 MFSD10	5.33e-06	470	181	14	MM1053
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	HSPG2 ADGRG1 LCN6 STC2 SLCO2A1 TMEM44 NEURL1B ACKR1	1.50e-06	197	181	8	1a137af40697137bb9d2b5caf2b1ffda55f04461
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Endothelial-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	HSPG2 ADGRG1 LCN6 STC2 SLCO2A1 TMEM44 NEURL1B ACKR1	1.50e-06	197	181	8	f969685dee212f33a6f09e54c0cd1fd24ffef546
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSPG2 ADGRG1 LCN6 STC2 SLCO2A1 TMEM44 NEURL1B ACKR1	1.50e-06	197	181	8	96d63a8d00583e2aa0a38412e2ae27e23f399493
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Bronchial_vessel\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	HSPG2 ADGRG1 LCN6 PTGIS SLCO2A1 TMEM44 NEURL1B ACKR1	1.62e-06	199	181	8	53b6a661d381b1ed3ea96e61e8bd1750de7d9fda
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Bronchial_vessel\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	HSPG2 ADGRG1 LCN6 PTGIS SLCO2A1 TMEM44 NEURL1B ACKR1	1.62e-06	199	181	8	9c753043024871b1f1436fc39defac4da85e10cd
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Bronchial_vessel-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSPG2 ADGRG1 LCN6 PTGIS SLCO2A1 TMEM44 NEURL1B ACKR1	1.62e-06	199	181	8	d017dd91f9b10038f1f83753a766e534da2dbe89
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	BHLHE41 LPAR5 GGT6 C5AR2 TLCD2 SLC2A5 MLXIPL	2.88e-06	151	181	7	2f9b3e14c2fa6e2b1976ca6ab2031b63bf5e3e64
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_large-bowel / Manually curated celltypes from each tissue	GGT6 PBX4 TLCD2 SLC22A18 CD7 BRAF NEURL1B	3.00e-06	152	181	7	95944864ce7539ff8de028f5700694931338f3ff
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC6 NLRP6 ACSL1 SLC22A18 MLXIPL C4B SLC4A4	3.57e-06	156	181	7	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDE4D CALHM2 PPOX FAN1 CD7 MED12L MMS19	4.39e-06	161	181	7	2849fbc9611af208241b33da3cd18290aafe426b
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EVC ATP10A TGFBI THADA ADGRG2 CIITA WDR90	6.28e-06	170	181	7	ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D231\|Adult / Lineage, Cell type, age group and donor	HSPG2 PTGIS CC2D2B SLCO2A1 DCHS1 NEURL1B ACKR1	7.32e-06	174	181	7	2dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCell	facs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARID3A LPAR5 ADRA1A CD7 CIITA NDUFAF6 DNA2	8.49e-06	178	181	7	89f0537459a321ded956bf70ad56fefc0854f8b0
ToppCell	Endothelial-A-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 LCN6 PTGIS BGN SLCO2A1 ACKR1 CDH13	8.80e-06	179	181	7	138fd6ba6bdbd0ad01c574168addf720b67a0fea
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIP2A NR1H3 HMGCR VWA7 SLC7A4 C4A NEURL1B	9.81e-06	182	181	7	39f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCell	facs-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC6 ACSL1 SLC22A18 ADRA1B AGL C4B SLC4A4	1.02e-05	183	181	7	d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell	Endothelial-A-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 LCN6 STC2 SLCO2A1 DCHS1 NEURL1B ACKR1	1.02e-05	183	181	7	2c3f2c25c38f0598b4787d2ec335efe00fdc9751
ToppCell	Endothelial-A-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 PTGIS BGN SLCO2A1 DCHS1 ACKR1 CDH13	1.09e-05	185	181	7	dee0b7ba2f338f0979d2306aedf52ac35a36b60c
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ANK2 PDGFRA RHOBTB3 BGN TGFBI ADGRG2 LRRC15	1.09e-05	185	181	7	427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 SLC43A1 PTCHD1 STC2 DCHS1 SLC4A4 CDH13	1.13e-05	186	181	7	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	10x5'v1-week_12-13-Lymphocytic_NK-T_NK-mature_NK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PDE4D ADGRG1 RNF213 CD7 IL21R SLC4A4 NLRC3	1.13e-05	186	181	7	165d02be3b3eaeb8784a2b0b2020928b21a19bc7
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	ANK2 PDGFRA BGN ADGRG2 ACKR1 LRRC15 GP1BA	1.17e-05	187	181	7	e04fb35f2f5b120659d06b5ae427ab1ec56d5c36
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	HSPG2 ATP10A PTGIS SLCO2A1 TMEM44 PLXNA2 CDH13	1.17e-05	187	181	7	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 SPTBN5 STARD9 SLCO2A1 TMEM44 NEURL1B CDH13	1.17e-05	187	181	7	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	Endothelial-A-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 LCN6 PTGIS BGN SLCO2A1 DCHS1 ACKR1	1.21e-05	188	181	7	0824d567356d360fd8e78e840c30529c139f98a1
ToppCell	COPD-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	ASXL1 PDE4D CD7 LRRIQ1 IL21R TANC1 DNAH5	1.21e-05	188	181	7	186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell	Endothelial-A-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 LCN6 STC2 SLCO2A1 DCHS1 NEURL1B ACKR1	1.25e-05	189	181	7	04b565855f58ca0f343904d04be657b66e109076
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ANK2 ADGRG1 CDCP1 OPRD1 ACSL1 MLXIPL SLC7A4	1.30e-05	190	181	7	5f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell	Endothelial-A-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 LCN6 PTGIS BGN SLCO2A1 DCHS1 ACKR1	1.34e-05	191	181	7	f702dfe88a9b04091dae87df61b2b4f43525f86a
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMC4 SLC22A18 LRRIQ1 STC2 FGFR2 FHIP1A DNAH11	1.34e-05	191	181	7	b94e66ac71e73f46b0323d424e7b8b906751d584
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	ABCA3 PDE4D ABCC6 TANC1 FGFR2 DNAH5 FHIP1A	1.39e-05	192	181	7	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	droplet-Bladder-nan-3m-Epithelial-bladder_mesenchymal_cell_(Scara5+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 PDGFRA RHOBTB3 PAQR6 PTGIS BGN C4B	1.43e-05	193	181	7	80380358f44c2f4781676ec0f1fa94d4c69080d6
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	ASXL1 ARID3A MSH2 ABCC6 SH3BP4 MLXIPL NDUFAF6	1.43e-05	193	181	7	503a979328c68b096680b71359a26f02fafdff35
ToppCell	10x5'v1-week_12-13-Lymphocytic_NK-T_NK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PDE4D ADGRG1 RNF213 CD7 IL21R SLC4A4 NLRC3	1.48e-05	194	181	7	ec7e0ca6c9a2f63938e06ee771da09eff14fc3b5
ToppCell	10x5'v1-week_12-13-Lymphocytic_NK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PDE4D ADGRG1 RNF213 CD7 IL21R SLC4A4 NLRC3	1.48e-05	194	181	7	5afe7f48d3383f3dac18765f97999c8b6936dc1b
ToppCell	Endothelial-A-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	ADGRG1 LCN6 PTGIS STC2 SLCO2A1 DCHS1 ACKR1	1.53e-05	195	181	7	c3a0aa34b672c99cb3a2a4e9218412dbd19da3ca
ToppCell	368C-Endothelial_cells-Endothelial-A_(Artery)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 ADGRG1 LCN6 STC2 SLCO2A1 NEURL1B ACKR1	1.64e-05	197	181	7	951f18f326967206adbbfc422cce9eea3d2e0854
ToppCell	P03-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ANK2 PDGFRA PTGIS BGN TGFBI ADGRG2 LRRC15	1.64e-05	197	181	7	2cec938caf6ffd031cea37277071487e59b2c71c
ToppCell	368C-Endothelial_cells-Endothelial-A_(Artery)\|368C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 ADGRG1 LCN6 STC2 SLCO2A1 NEURL1B ACKR1	1.64e-05	197	181	7	7caa2c86dc4d50b57a7db8f7278d1588282ad6db
ToppCell	390C-Endothelial_cells-Endothelial-A_(Artery)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 LCN6 STC2 SLCO2A1 DCHS1 NEURL1B ACKR1	1.69e-05	198	181	7	f83956c4b13b5d0a0c6e3d9f580dbf99649ef175
ToppCell	5'-Adult-Distal_Rectal-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 LCN6 PTGIS BGN SLCO2A1 ACKR1 CDH13	1.69e-05	198	181	7	8d6b0b9da7c1e64155cbcbb04ad38d129a29030c
ToppCell	368C-Endothelial_cells\|368C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 ADGRG1 LCN6 STC2 SLCO2A1 NEURL1B ACKR1	1.69e-05	198	181	7	9a2c2201baee51581733e183065298a97eba4553
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 LCN6 PTGIS BGN SLCO2A1 ACKR1 CDH13	1.69e-05	198	181	7	d1f54ed3ef5e05ebda7da999e172d168dc6802cd
ToppCell	390C-Endothelial_cells-Endothelial-A_(Artery)\|390C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 LCN6 STC2 SLCO2A1 DCHS1 NEURL1B ACKR1	1.69e-05	198	181	7	5b5ccce5de82ea041465e656147cec3b8beb865b
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_venous\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	HSPG2 LCN6 SACS SLCO2A1 DCHS1 NEURL1B ACKR1	1.75e-05	199	181	7	d359f3e1595ba8d8a3dc9eb2e8f2b61f3247c7a1
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Myeloid-Megakaryocyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	RHOBTB3 DHRS13 NUTM2D PAQR6 TMEM44 TANC1 NLRC3	1.75e-05	199	181	7	6e7f7214317f2af2ba8523df9896f54b7294d58a
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Myeloid\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	RHOBTB3 DHRS13 NUTM2D PAQR6 TMEM44 TANC1 NLRC3	1.75e-05	199	181	7	5f499595597c10857bba8272f62afe4d32d733ac
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_venous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HSPG2 ADGRG1 LCN6 STC2 SLCO2A1 NEURL1B ACKR1	1.75e-05	199	181	7	6fb81388c5045e81c3849a7136bdff3f953f044e
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	LRRC38 RHOBTB3 EYS ADRA1A GPR149 TANC1 SLC4A4	1.81e-05	200	181	7	1276bfa911fddada4235e12e3081baa53164574b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MAN2B1 CDCP1 ARPC1B SLC2A5 ACSL1 TGFBI MRTFA	1.81e-05	200	181	7	5f1de1f9305e1784c12d526f6c8bdd7d56229f9b
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB--L2-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	LRRC38 RHOBTB3 AAK1 EYS CD7 TANC1 CDH13	1.81e-05	200	181	7	5ec469267747dce3601c1d8ad01af89fa5b29acc
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB\|Neuronal / cells hierarchy compared to all cells using T-Statistic	LRRC38 RHOBTB3 AAK1 EYS CD7 TANC1 CDH13	1.81e-05	200	181	7	e79d93d55b25804f2608185168da472301b6ebca
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	LRRC38 RHOBTB3 AAK1 EYS CD7 TANC1 CDH13	1.81e-05	200	181	7	320d5a3a1e7da2fa8f1a164e29e180ec8ac9889c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-Z\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	BHLHE41 LPAR5 GGT6 C5AR2 TLCD2 MLXIPL	1.91e-05	135	181	6	9f9d0787a2e99207a9caa88a85565189ab8b940a
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C5AR2 TLCD2 STC2 NDUFAF6 FGFR2 DNA2	2.64e-05	143	181	6	b4ed3855652fdf32f97cb7c18cab4f4f4c24d5c7
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_3\|367C / Donor, Lineage, Cell class and subclass (all cells)	MYO7B PBX4 THADA CD7 UTS2 DZIP3	3.86e-05	153	181	6	da1bff9928d8c61bb1c389d45fd897cfa4bed023
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_E\|390C / Donor, Lineage, Cell class and subclass (all cells)	VGF DHRS13 PAQR6 CHRNE DZIP3 PHLPP2	4.15e-05	155	181	6	98d8432739965dd1ab77c899cb6321f7f05eaa46
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-Migrating_MyoFibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	PDGFRA SLC43A1 FOCAD TGFBI ADGRG2 PLXNA2	4.15e-05	155	181	6	1882fa5fd25f77d6e3ac47b613f6fb3c67d8e50c
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage-microglial_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	BHLHE41 ICOSLG ADGRG1 SLC2A5 MLXIPL MED12L	4.46e-05	157	181	6	d4908cafd8870c1c225817f589ea2bce116ac7ab
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ADGRB2 IPO4 LRRIQ1 ADGRG2 WDR90 DNAH11	4.46e-05	157	181	6	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	normal_Pleural_Fluid-T/NK_cells-CD4+_Th\|normal_Pleural_Fluid / Location, Cell class and cell subclass	ABCA3 ANK2 SLC43A1 ADGRG1 CD7 ASTN1	4.78e-05	159	181	6	ebd840ac2b07e62086ee7b5bb01c21804a0fdc7b
ToppCell	10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-LMPP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CDCP1 ATP10A MLXIPL CD7 TMEM44 PLCB3	4.95e-05	160	181	6	60fa1c717410aad7e8647703cb416cd7617cac29
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 CACNG8 ADGRG2 SLCO2A1 AP5Z1 ACKR1	4.95e-05	160	181	6	33050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCell	droplet-Lung-nan-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKD1L2 SLC22A18 PTCHD1 MDN1 CIITA GPR149	5.68e-05	164	181	6	a67dd181eba275c191f4d0cab13df30eaa3ad913
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	OPRD1 SH3BP4 PTCHD1 MED12L NLRC5 WDR90	5.88e-05	165	181	6	c39f0479955c4e23921f7a450d3bc251a002200f
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PDE4D PTCHD1 ADRA1B HSD17B11 DNAH5 FHIP1A	6.08e-05	166	181	6	c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HSPG2 PTGIS CC2D2B SLCO2A1 TMEM44 ACKR1	6.28e-05	167	181	6	d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231\|Adult / Lineage, Cell type, age group and donor	OBSCN STC2 STARD9 SLCO2A1 TMEM44 CDH13	6.28e-05	167	181	6	5af9127bae05768a5164d5708a4ad37edca99324
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ICOSLG GLB1L OBSCN BGN C4A C4B	6.49e-05	168	181	6	d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCell	NS-critical-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	HSPG2 ADGRG1 PAQR6 SH3BP4 FGFR2 SLC4A4	6.71e-05	169	181	6	aec97583b23112060437b619cb429dc32f29285f
ToppCell	droplet-Liver-HEPATOCYTES-1m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM53 CHRNE CD7 CEP250 IL21R FHIP1A	6.71e-05	169	181	6	d721dbb317a88113b4f76688111908d00f23e899
ToppCell	ileum\|World / shred on tissue and cell subclass	MYO7B TLCD2 SLC2A5 SLC22A18 MLXIPL PHLPP2	6.93e-05	170	181	6	9f1211bd4287620e19a59f21e6ecdca3e42e0260
ToppCell	Influenza_Severe-B_intermediate\|World / Disease group and Cell class	BHLHE41 ANK2 LPAR5 EYS MED12L FCRL4	7.16e-05	171	181	6	4d33e1dc1efc423dbdd5f4cca6d6440a68add8d0
ToppCell	droplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AAK1 CHRNE CD7 CEP250 IL21R SNAPC4	7.16e-05	171	181	6	2e7cc311005958af52f39ca6c310c85b43a85aaf
ToppCell	droplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AAK1 CHRNE CD7 CEP250 IL21R SNAPC4	7.16e-05	171	181	6	4b599f953c8e5b947b2c8bbbf7fe6f9dc388e336
ToppCell	droplet-Fat-Mat-18m-Lymphocytic-lymphocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE4D CHRNE FAN1 MDN1 IL21R NLRC5	7.39e-05	172	181	6	226de1a5d4a360d3ae01b0235fea19521ec623a0
ToppCell	droplet-Liver-LIVER-NPC-1m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP10A ARPC1B OPRD1 TGFBI CIITA DNA2	7.39e-05	172	181	6	6aab59add5b180cee0ca31179c620e89d352d5c1
ToppCell	Endothelial-A-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 BGN SLCO2A1 DCHS1 NEURL1B ACKR1	7.39e-05	172	181	6	a3201773a25832e92dd113fad165f1ecd37f5e91
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 LRRC38 INTS1 PAQR6 MLXIPL DZIP3	7.64e-05	173	181	6	a5172dee859bf6c2eed46c48bd64dfef0ff9f28f
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DHRS13 CIITA TELO2 CCDC138 NEURL1B DNAH11	7.64e-05	173	181	6	15af4a0f7516dbf5c93ba66a19aca073ebe30d04
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 LRRC38 INTS1 PAQR6 MLXIPL DZIP3	7.64e-05	173	181	6	639b5b0b33ce5aa0bc26363c059717012ddc14c0
ToppCell	368C-Endothelial_cells-Endothelial-D\|368C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 ADGRG1 LCN6 STC2 SLCO2A1 ACKR1	8.13e-05	175	181	6	c4088b5f9fa145869cf5dd8bee7680b1c8fada42
ToppCell	368C-Endothelial_cells-Endothelial-D-\|368C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 ADGRG1 LCN6 STC2 SLCO2A1 ACKR1	8.13e-05	175	181	6	ca0d3e3a0a271cccdd3881b055fecb626712478d
ToppCell	droplet-Kidney-nan-18m-Lymphocytic-T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYSLTR2 CD7 IL21R NLRC5 TNF RINL	8.13e-05	175	181	6	82d48bfade1bc2f99848b45e55c8fb0ecc999ed7
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KCNK7 PTGIS CIITA SLCO2A1 TMEM44 ACKR1	8.13e-05	175	181	6	90302e8a44858ef3b2a165b88284d4788d591a99
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CALHM2 THADA MDN1 CD7 NEURL1B ACKR1	8.39e-05	176	181	6	6b4afd2c9268172063fe5832896bea15e862579e
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC2A10 LRRIQ1 ULK4 SNAPC4 GP1BA DNAH11	8.66e-05	177	181	6	e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCell	facs-GAT-Fat-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE4D CHRNE CD7 IL21R NLRC5 RINL	8.93e-05	178	181	6	44634ba10da34307d6217646b221ddf5d7a65fb0
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 SLC2A10 STARD9 SLCO2A1 DCHS1 DNA2	8.93e-05	178	181	6	375156ba1c7b8592bf733c75f24968161f7cfa09
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPR6 SLC43A1 ADRA1B LRRIQ1 RXFP2 CDH13	9.21e-05	179	181	6	747a32460b257fffca30527b56a74720eb9c12e4
ToppCell	Endothelial\|World / shred by cell class for turbinate	MYO7B LCN6 PTGIS BGN STC2 ACKR1	9.21e-05	179	181	6	052b2681974be00efb8503fa4e2c85d91d5ebd06
ToppCell	Globus_pallidus-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	C5AR2 SLC2A5 MLXIPL IL21R TNF	9.44e-05	112	181	5	73248a855b644385ed6670a72f10b1d9e4371de9
ToppCell	Globus_pallidus-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	C5AR2 SLC2A5 MLXIPL IL21R TNF	9.44e-05	112	181	5	df524107893efb96ac29b823a3568c6b2602c00a
ToppCell	Globus_pallidus-Hematopoietic-MICROGLIA-MI2(C1qb)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	C5AR2 SLC2A5 MLXIPL IL21R TNF	9.44e-05	112	181	5	2378da89ce8db96615763728801e1d1320ffd14a
ToppCell	Globus_pallidus-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	C5AR2 SLC2A5 MLXIPL IL21R TNF	9.44e-05	112	181	5	f206acd2c785dd132c6c122466cfdb3cde443caa
ToppCell	Globus_pallidus-Hematopoietic-MICROGLIA\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	C5AR2 SLC2A5 MLXIPL IL21R TNF	9.44e-05	112	181	5	ecda7c1c1c6df419cc48cd4f04acb9dfbc6f69f7
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_2\|368C / Donor, Lineage, Cell class and subclass (all cells)	ORC6 SLC43A1 PBX4 MEI1 CD7 NLRC3	9.50e-05	180	181	6	551b8de8d933d11bcd3897aeb2fd033355f958e2
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HSPG2 PTGIS CC2D2B SLCO2A1 SLC25A29 ACKR1	9.50e-05	180	181	6	27e8bbee388e64dd79d70b160b76d45b1f398006
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC43A1 EVC SACS SLC4A4 ACKR1 TMEM239	9.50e-05	180	181	6	c4068fe47408cfd899131a85fa4b7e5908926f94
ToppCell	facs-Lung-EPCAM-3m-Myeloid-Dendritic_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM53 ARID3A LPAR5 ADRA1A CD7 NDUFAF6	9.50e-05	180	181	6	710526abedc8e0f9ba19ad69220df4c9468ada8f
Drug	2-FPE	ADRA1B ADRA1A PES1	4.86e-07	3	180	3	CID000127900
Drug	4-FPE	ADRA1B ADRA1A PES1	4.86e-07	3	180	3	CID000127903
Drug	6-FPE	ADRA1B ADRA1A PES1	4.86e-07	3	180	3	CID000183822
Drug	Heliotrine [303-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A	ICOSLG SLC52A1 SLC43A1 MLXIPL CIITA SLCO2A1 CEP250 MRTFA LRRC15	2.61e-05	195	180	9	6035_UP
Drug	Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; PC3; HT_HG-U133A	ICOSLG ADGRB2 SLC2A5 CALHM2 SPTBN5 STC2 IL21R DCHS1 PHLPP2	2.83e-05	197	180	9	3801_UP
Drug	St-1913	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000123528
Drug	Neldazosin	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000065908
Drug	DL-028	ADRA1B ADRA1A	6.22e-05	2	180	2	CID005487531
Drug	quinazosin	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000027486
Drug	hydroxyphenacetyl aminoclonidine	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000173558
Drug	Midodrine	ADRA1B ADRA1A	6.22e-05	2	180	2	DB00211
Drug	sulfonterol	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000170372
Drug	AC1L27FT	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000016192
Drug	paveril	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000006855
Drug	tolazine	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000101252
Drug	piclonidine	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000068914
Drug	Lidanserin	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000068919
Drug	FCE 22716	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000125720
Drug	SKF 101253	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000135152
Drug	ASL-7022	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000173406
Drug	hoquizil	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000030690
Drug	Methoxamine	ADRA1B ADRA1A	6.22e-05	2	180	2	DB00723
Drug	Prestwick_774	ADRA1B ADRA1A	6.22e-05	2	180	2	CID006420011
Drug	compound 44-549	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000191431
Drug	5-dembs	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000130379
Drug	levomepromazine sulfoxide	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000165566
Drug	R 56	ADRA1B ADRA1A	6.22e-05	2	180	2	CID009578362
Drug	dihydrolysergic acid amide	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000151000
Drug	St-404	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000191786
Drug	AC1MBW4N	ADRA1B ADRA1A	6.22e-05	2	180	2	CID002732234
Drug	Myordil	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000011282
Drug	5-cfmbs	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000183818
Drug	IK29	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000183825
Drug	pyrroxan	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000036302
Drug	dihydroergonine	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000193205
Drug	Indoramin	ADRA1B ADRA1A	6.22e-05	2	180	2	ctd:D007217
Drug	penta-O-ethylquercetin	ADRA1B ADRA1A	6.22e-05	2	180	2	CID000133942
Drug	thromboxane	CYSLTR2 PTGIS TGFBI ADRA1B ADRA1A SLCO2A1 C4A TNF GP1BA	7.41e-05	223	180	9	CID000114873
Drug	lofexidine	OPRD1 ADRA1B ADRA1A	7.65e-05	11	180	3	CID000030667
Drug	PG-S	PTGIS BGN SLCO2A1 PES1	8.82e-05	30	180	4	CID000446796
Drug	AC1NAPOQ	ADRA1B ADRA1A PES1	1.01e-04	12	180	3	CID004480714
Drug	indomethacin	CYSLTR2 SLC52A1 PTGIS ABCC6 TGFBI ADRA1B ADRA1A CD7 UTS2 SLCO2A1 FNIP1 C4A TRPV3 TNF HBZ MFSD10	1.24e-04	690	180	16	CID000003715
Drug	Sordinol	MLXIPL ADRA1B ADRA1A	1.31e-04	13	180	3	CID000012453
Drug	Cyanocobalamin [68-19-9]; Down 200; 3uM; MCF7; HT_HG-U133A	BHLHE41 HSPG2 SLC52A1 GLB1L SBF1 AP5Z1 PLCB3 MRTFA	1.50e-04	192	180	8	4395_DN
Drug	Cyclacillin [3485-14-1]; Up 200; 11.8uM; PC3; HT_HG-U133A	ICOSLG PDE4D GLB1L ADGRG1 SLCO2A1 DZIP3 SNAPC4 MRTFA	1.56e-04	193	180	8	4536_UP
Drug	salbutamol	CYSLTR2 PDE4D PDGFRA OPRD1 ADRA1B ADRA1A TNF	1.65e-04	146	180	7	CID000002083
Drug	fenspiride	PDE4D ADRA1B ADRA1A	1.66e-04	14	180	3	CID000003344
Drug	Fusidic acid sodium salt [751-94-0]; Down 200; 7.4uM; HL60; HT_HG-U133A	HSPG2 ANK2 RHOBTB3 INTS1 IPO4 TELO2 AP5Z1 PLCB3	1.67e-04	195	180	8	1293_DN
Drug	Ribavirin [36791-04-5]; Up 200; 16.4uM; PC3; HT_HG-U133A	ICOSLG ABCA3 TMEM53 PDE4D PAQR6 PTGIS TELO2 SNAPC4	1.73e-04	196	180	8	7316_UP
Drug	Digoxigenin [1672-46-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A	BHLHE41 ATP6V1B1 GLB1L PTGIS ADRA1A FGFR2 SNAPC4 LRRC15	1.73e-04	196	180	8	3397_DN
Drug	Ketoconazole [65277-42-1]; Down 200; 7.6uM; PC3; HT_HG-U133A	PDE4D MRPL44 ADGRG2 TELO2 AP5Z1 SNAPC4 PLXNA2 MRTFA	1.73e-04	196	180	8	4624_DN
Drug	alpha-Santonin [481-06-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A	ICOSLG SLC52A1 ABCA7 PTGIS SLC2A5 FGFR2 SLC4A4 LRRC15	1.79e-04	197	180	8	3877_UP
Drug	N-Acetyl-L-leucine [1188-21-2]; Up 200; 23uM; HL60; HT_HG-U133A	ICOSLG RHOBTB3 HHLA1 ATP10A UTS2 CEP250 SLC4A4 TNPO3	1.79e-04	197	180	8	3085_UP
Drug	Methylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; PC3; HT_HG-U133A	HSPG2 PDE4D PKDREJ SLC2A5 CALHM2 SPTBN5 CD7 SLC4A4	1.79e-04	197	180	8	4618_UP
Drug	Metanephrine hydrochloride DL [881-95-8]; Down 200; 17.2uM; MCF7; HT_HG-U133A	MRPL44 C5AR2 FAN1 BRAF SBF1 PLCB3 SNAPC4 SLC4A4	1.79e-04	197	180	8	1515_DN
Drug	8-isoprostaglandin E1	PTGIS TGFBI ADRA1B ADRA1A SLCO2A1 PLCB3 ACP4 TNF GP1BA	1.81e-04	251	180	9	CID000000214
Drug	Remoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; MCF7; HT_HG-U133A	ICOSLG INTS1 AAK1 ADGRG1 ATP10A ABCA7 AP5Z1 PLCB3	1.85e-04	198	180	8	5443_UP
Drug	(+/-)-thalidomide; Down 200; 100uM; MCF7; HG-U133A	ICOSLG CYSLTR2 ANK2 GLB1L ATP10A USP20 CIITA SLC4A4	1.85e-04	198	180	8	266_DN
Drug	Clonidine hydrochloride [4205-91-8]; Up 200; 15uM; MCF7; HT_HG-U133A	ATP6V1B1 SZT2 ABCA7 CD7 SLCO2A1 CEP250 FGFR2 LRRC15	1.85e-04	198	180	8	3172_UP
Drug	Rec 15/2739	ADRA1B ADRA1A	1.86e-04	3	180	2	CID000148842
Drug	Farial	ADRA1B ADRA1A	1.86e-04	3	180	2	CID000065979
Drug	mephentermine	ADRA1B ADRA1A	1.86e-04	3	180	2	CID000003677
Drug	1-(2-(3-methoxyphenyl)ethyl)phenoxy-3-(dimethylamino)-2-propanol	ADRA1B ADRA1A	1.86e-04	3	180	2	ctd:C099060
Drug	Alfuzosin	ADRA1B ADRA1A	1.86e-04	3	180	2	DB00346
Drug	Phenylephrine	ADRA1B ADRA1A	1.86e-04	3	180	2	DB00388
Drug	Dapiprazole	ADRA1B ADRA1A	1.86e-04	3	180	2	DB00298
Drug	Phendimetrazine	ADRA1B ADRA1A	1.86e-04	3	180	2	DB01579
Drug	dalvastatin	HMGCR C4A	1.86e-04	3	180	2	CID006436001
Drug	2-(beta-(3-iodo-4-hydroxyphenyl)ethylaminomethyl)tetralone	ADRA1B ADRA1A	1.86e-04	3	180	2	ctd:C048008
Drug	SY28	ADRA1B ADRA1A	1.86e-04	3	180	2	CID000014606
Drug	MOPEG sulfate	ADRA1B ADRA1A	1.86e-04	3	180	2	CID000004182
Drug	verticillatine	ADRA1B ADRA1A	1.86e-04	3	180	2	CID000176717
Drug	2-aminothiophenol	C4A C4B	1.86e-04	3	180	2	ctd:C005464
Drug	Tamsulosin	ADRA1B ADRA1A	1.86e-04	3	180	2	DB00706
Drug	abanoquil	ADRA1B ADRA1A	1.86e-04	3	180	2	ctd:C058534
Drug	ifoxetine	ADRA1B ADRA1A	1.86e-04	3	180	2	CID000071971
Drug	DB-6,7-ADTN	ADRA1B ADRA1A	1.86e-04	3	180	2	CID000129816
Drug	chlorethylclonidine	ADRA1B ADRA1A	1.86e-04	3	180	2	ctd:C051731
Drug	Wy 25309	ADRA1B ADRA1A	1.86e-04	3	180	2	CID000133818
Drug	XB513	ADRA1B ADRA1A	1.86e-04	3	180	2	CID000183813
Drug	metrenperone	ADRA1B ADRA1A	1.86e-04	3	180	2	CID000072005
Drug	Ronidazole [7681-76-7]; Up 200; 20uM; HL60; HT_HG-U133A	ADGRB2 PKDREJ ABCA7 ABCC6 ADGRG2 CIITA GLRB GP1BA	1.92e-04	199	180	8	6134_UP
Drug	(cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; MCF7; HT_HG-U133A	ICOSLG SLC52A1 SLC2A5 CHRNE CEP250 ASTN1 MRTFA PHLPP2	1.98e-04	200	180	8	6049_UP
Disease	systemic lupus erythematosus (is_implicated_in)	CIITA IL21R C4A C4B TNF	3.41e-05	62	175	5	DOID:9074 (is_implicated_in)
Disease	Congenital small ears	ORC6 EVC HMX1 FGFR2	1.02e-04	41	175	4	C0152423
Disease	Moyamoya Disease	RNF213 ABCC6 SLC2A10	1.31e-04	17	175	3	C0026654
Disease	familial non-medullary thyroid cancer	MSH2 BRAF	2.08e-04	4	175	2	C4733333
Disease	renal tubular acidosis (is_implicated_in)	ATP6V1B1 SLC4A4	2.08e-04	4	175	2	DOID:14219 (is_implicated_in)
Disease	Kartagener syndrome (is_implicated_in)	DNAH5 DNAH11	2.08e-04	4	175	2	DOID:0050144 (is_implicated_in)
Disease	cholesterol to total lipids in small VLDL percentage	HMGCR KCNK7 MLXIPL NLRC5	2.40e-04	51	175	4	EFO_0022242
Disease	Bronchiectasis	TNF DNAH5 DNAH11	2.91e-04	22	175	3	C0006267
Disease	Distal Renal Tubular Acidosis	ATP6V1B1 SLC4A4	3.46e-04	5	175	2	C1704380
Disease	hypertension	SZT2 RNF213 NR1H3 MSH2 RXFP2 PLCB3 TNF CDH13	5.19e-04	307	175	8	EFO_0000537
Disease	retinitis pigmentosa (implicated_via_orthology)	EYS CEP250 FGFR2	5.40e-04	27	175	3	DOID:10584 (implicated_via_orthology)
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	NR1H3 HMGCR MLXIPL TNF	6.10e-04	65	175	4	DOID:0080208 (biomarker_via_orthology)
Disease	level of Sphingomyelin (d42:2) in blood serum	CHRNE MLXIPL SLC4A4	6.69e-04	29	175	3	OBA_2045183
Disease	dehydroepiandrosterone sulphate measurement	ARPC1B THADA MFSD14B NEURL1B	7.24e-04	68	175	4	EFO_0007001
Disease	level of Sphingomyelin (d38:1) in blood serum	SLC52A1 CHRNE SLC4A4	7.40e-04	30	175	3	OBA_2045180
Disease	Lupus Erythematosus, Systemic	PCNX3 IL21R C4A C4B	8.52e-04	71	175	4	C0024141
Disease	level of Sphingomyelin (d40:1) in blood serum	SLC52A1 CHRNE SLC4A4	8.96e-04	32	175	3	OBA_2045182
Disease	monocyte count	ASXL1 SZT2 PBX4 MEI1 VWA7 NLRP6 MLXIPL THADA NEU1 CIITA TELO2 MED12L NLRC5 FCRL4 NEURL1B ACKR1 TMEM239 MRTFA	8.98e-04	1320	175	18	EFO_0005091
Disease	chemotherapy-induced alopecia, methylcobalamin deficiency type cblE	DNAH5 CDH13	9.57e-04	8	175	2	EFO_0005400, MONDO_0009354
Disease	premature menopause (biomarker_via_orthology)	NR1H3 HMGCR	9.57e-04	8	175	2	DOID:10787 (biomarker_via_orthology)
Disease	renal tubular acidosis (implicated_via_orthology)	ATP6V1B1 SLC4A4	9.57e-04	8	175	2	DOID:14219 (implicated_via_orthology)
Disease	Colorectal Carcinoma	ABCA3 ANK2 OBSCN PBX4 MSH2 ABCC6 PPOX BRAF SACS SLCO2A1 DCHS1 TNF	1.04e-03	702	175	12	C0009402
Disease	Lung Neoplasms	BHLHE41 PTGIS SLC22A18 BRAF TNF FGFR2 CDH13	1.07e-03	265	175	7	C0024121
Disease	Malignant neoplasm of lung	BHLHE41 PTGIS SLC22A18 BRAF TNF FGFR2 CDH13	1.09e-03	266	175	7	C0242379
Disease	response to vaccine, cytokine measurement	PDE4D SLC52A1 ATP10A PTCHD1 SLC4A4	1.13e-03	131	175	5	EFO_0004645, EFO_0004873
Disease	Lung diseases	PDGFRA TNF DNAH5 DNAH11	1.21e-03	78	175	4	C0024115
Disease	Colorectal Neoplasms	ABCA3 MSH2 ABCC6 PPOX BRAF SLCO2A1 TNF	1.38e-03	277	175	7	C0009404
Disease	platelet glycoprotein ib alpha chain measurement	CHRNE GP1BA	1.53e-03	10	175	2	EFO_0020645
Disease	Graves' disease (is_implicated_in)	C4A C4B TNF	1.60e-03	39	175	3	DOID:12361 (is_implicated_in)
Disease	dilated cardiomyopathy (is_marker_for)	OBSCN CACNG8 TNF	1.60e-03	39	175	3	DOID:12930 (is_marker_for)
Disease	response to radiation	ATP10A NDUFAF6 TANC1 DNAH5	1.89e-03	88	175	4	GO_0009314
Disease	breast cancer (is_implicated_in)	MSH2 SLC22A18 TNF FGFR2 CDH13	2.05e-03	150	175	5	DOID:1612 (is_implicated_in)
Disease	lymphocyte percentage of leukocytes	PBX4 NR1H3 ABCA7 THADA NLRC5 NDUFAF6 PLCB3 NEURL1B SNAPC4 ACKR1 MRTFA	2.16e-03	665	175	11	EFO_0007993
Disease	endometrial carcinoma (is_implicated_in)	BRAF CDH13	2.22e-03	12	175	2	DOID:2871 (is_implicated_in)
Disease	Spina Bifida	PDGFRA FGFR2	2.22e-03	12	175	2	C0080178
Disease	Status Dysraphicus	PDGFRA FGFR2	2.22e-03	12	175	2	C0038219
Disease	AL amyloidosis	ULK4 DNAH11	2.22e-03	12	175	2	MONDO_0019438
Disease	level of C-X-C motif chemokine 2 in blood serum	TELO2 ACKR1	2.22e-03	12	175	2	OBA_2041207
Disease	Rachischisis	PDGFRA FGFR2	2.22e-03	12	175	2	C0266508
Disease	cholesterol to total lipids in large VLDL percentage	HMGCR MLXIPL NLRC5	2.42e-03	45	175	3	EFO_0022236
Disease	Craniofacial Abnormalities	HSPG2 PDGFRA PBX4 HMX1 FGFR2	2.43e-03	156	175	5	C0376634
Disease	cardiomyopathy (biomarker_via_orthology)	UTS2 TNF	2.61e-03	13	175	2	DOID:0050700 (biomarker_via_orthology)
Disease	esophageal squamous cell carcinoma	PDE4D HHLA1	2.61e-03	13	175	2	EFO_0005922
Disease	ceramide measurement	PDE4D POLR1A DHRS13 ABCA7 EYS MDN1	2.87e-03	235	175	6	EFO_0010222
Disease	Kidney Failure, Chronic	HMGCR MLXIPL TNF	2.92e-03	48	175	3	C0022661
Disease	Neoplasm of lung	SLC22A18 BRAF	3.04e-03	14	175	2	cv:C0024121
Disease	Lung cancer	SLC22A18 BRAF	3.04e-03	14	175	2	cv:C0242379
Disease	LUNG CANCER	SLC22A18 BRAF	3.04e-03	14	175	2	211980
Disease	revision of total hip arthroplasty	VWA7 STRCP1	3.04e-03	14	175	2	EFO_0020973
Disease	multiple myeloma, monoclonal gammopathy	ULK4 DNAH11	3.04e-03	14	175	2	EFO_0000203, EFO_0001378
Disease	Kartagener syndrome (implicated_via_orthology)	DNAH5 DNAH11	3.04e-03	14	175	2	DOID:0050144 (implicated_via_orthology)
Disease	cholesteryl esters to total lipids in small VLDL percentage	HMGCR MLXIPL NLRC5	3.09e-03	49	175	3	EFO_0022256
Disease	acute graft vs. host disease, donor genotype effect measurement	EYS TMEM131	3.49e-03	15	175	2	EFO_0004599, EFO_0007892
Disease	level of C-X-C motif chemokine 3 in blood serum	TELO2 ACKR1	3.49e-03	15	175	2	OBA_2041208
Disease	triglycerides to total lipids in very large VLDL percentage	HMGCR KCNK7 MLXIPL	3.86e-03	53	175	3	EFO_0022340
Disease	intracerebral hemorrhage	ADGRG1 FHIP1A	3.97e-03	16	175	2	EFO_0005669
Disease	Malaria, susceptibility to	TNF ACKR1	3.97e-03	16	175	2	cv:C1970028
Disease	–	TNF ACKR1	3.97e-03	16	175	2	611162
Disease	C-X-C motif chemokine 6 measurement	TELO2 ACKR1	3.97e-03	16	175	2	EFO_0008059
Disease	clonal hematopoiesis mutation measurement	MSH2 SH3BP4 FGFR2	4.29e-03	55	175	3	EFO_0020949
Disease	Carcinoma in situ of stomach	BRAF FGFR2	4.49e-03	17	175	2	C0154060
Disease	alcoholic liver cirrhosis	PBX4 TMC4	4.49e-03	17	175	2	EFO_1000802
Disease	Benign neoplasm of stomach	BRAF FGFR2	4.49e-03	17	175	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	BRAF FGFR2	4.49e-03	17	175	2	C0496905
Disease	sphingomyelin 14:0 measurement	PDE4D THADA	4.49e-03	17	175	2	EFO_0010390
Disease	Familial Progressive Myoclonic Epilepsy	NEU1 SACS	4.49e-03	17	175	2	C0751777
Disease	Atypical Inclusion-Body Disease	NEU1 SACS	4.49e-03	17	175	2	C0751776
Disease	Myoclonic Epilepsies, Progressive	NEU1 SACS	4.49e-03	17	175	2	C0751778
Disease	Biotin-Responsive Encephalopathy	NEU1 SACS	4.49e-03	17	175	2	C0751780
Disease	May-White Syndrome	NEU1 SACS	4.49e-03	17	175	2	C0751782
Disease	Dentatorubral-Pallidoluysian Atrophy	NEU1 SACS	4.49e-03	17	175	2	C0751781
Disease	triglycerides to total lipids in medium HDL percentage	NR1H3 MLXIPL NLRC5	4.51e-03	56	175	3	EFO_0022333
Disease	non-alcoholic fatty liver disease	TMC4 MLXIPL NDUFAF6 SLC4A4 LMBRD1	4.69e-03	182	175	5	EFO_0003095
Disease	Malignant neoplasm of breast	ABCA3 ANK2 OBSCN PKDREJ SLC2A5 BGN SLC2A10 SLC22A18 ADRA1A BRAF STC2 NLRC5 TNF FGFR2	4.96e-03	1074	175	14	C0006142
Disease	rheumatoid arthritis (is_implicated_in)	CIITA C4B TNF	4.98e-03	58	175	3	DOID:7148 (is_implicated_in)
Disease	Malignant neoplasm of endometrium	MSH2 FGFR2	5.03e-03	18	175	2	C0007103
Disease	Gastric ulcer	VGF TNF	5.03e-03	18	175	2	C0038358
Disease	Action Myoclonus-Renal Failure Syndrome	NEU1 SACS	5.03e-03	18	175	2	C0751779
Disease	Carcinoma in situ of endometrium	MSH2 FGFR2	5.03e-03	18	175	2	C0346191
Disease	Substance abuse problem	CDCP1 OPRD1 ASTN1 CDH13	5.11e-03	116	175	4	C0740858
Disease	free cholesterol to total lipids in very large VLDL percentage	HMGCR KCNK7 MLXIPL	5.23e-03	59	175	3	EFO_0022289
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	MSH2 FAN1	5.60e-03	19	175	2	C2936783
Disease	carotid artery disease (is_marker_for)	HSPG2 UTS2	5.60e-03	19	175	2	DOID:3407 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LTLASLTLREFSVGP	nan	146	Q6ZRM9
GSERLTLLAPLNSVF	TGFBI	406	Q15582
LSVILSLRLATAFDP	ADGRB2	21	O60241
LFPQILASIELLARS	BRAF	706	P15056
ASALPAALAVISFLL	CD7	176	P09564
LSSERDFALLSLQVP	C4B	76	P0C0L5
SESSLPNLARSLLLV	AAK1	941	Q2M2I8
AAAALLRPDAALLSS	BHLHE41	311	Q9C0J9
AEALPSLAASLLRLS	CIITA	1036	P33076
APVSATVLTFLRAAL	ACSL1	436	P33121
LDLLFSVTLTPRTVD	CDCP1	651	Q9H5V8
ADLLLTSTVLPFSAI	ADRA1A	71	P35348
PLLALTFITDNSLVA	ARPC1B	246	O15143
VRLLFSSDSLILQAP	FCRL4	96	Q96PJ5
PSLALAVIRVNASSF	ADGRG2	446	Q8IZP9
TASLRAITELQSPAL	DNAH11	1391	Q96DT5
AVLSRSDPSLVLAFL	ABCA3	336	Q99758
LLDDSALPFFILTSV	ACKR1	56	Q16570
DLLLSFTVLPFSAAL	ADRA1B	91	P35368
LATAPDAALTLALVR	ARMC5	246	Q96C12
LTSEFVALLPALVDA	AP5Z1	446	O43299
LTAVLDLQLRSAPAA	AP5Z1	476	O43299
RSVPLAIAISLAIAA	SLC7A4	266	O43246
IEEAALLRSPLFSIL	DNHD1	1906	Q96M86
PSTLFLRLLQLATAS	DNHD1	3026	Q96M86
RFSLPSVLLLSLFSL	CDH13	696	P55290
SSIAFLTTLERILPE	HSD17B11	261	Q8NBQ5
LRPQLSFTAELTSLS	CC2D2B	471	Q6DHV5
TVSALPFLRENDLSI	ASTN1	41	O14525
ALPLLSSQTSVAERL	ASXL1	761	Q8IXJ9
ALAPVLFILAITAFR	ATP10A	111	O60312
PSEAALVSRALQLLA	ABCA7	416	Q8IZY2
ETSLSVPLLGRFLIF	CHRNE	296	Q04844
LLIRATFSSVPLAAS	HSPG2	1491	P98160
ALRASLLPQSLAAAA	GRSF1	96	Q12849
FALLIAISIFSADRP	NR1H3	356	Q13133
LALPSRDSEVLSAVA	ANK2	2411	Q01484
LVAPTLRSELTVAAA	PDGFRA	516	P16234
ATLSLARPSFSLVED	FGFR2	16	P21802
LFLRSISEPALLRTF	FHIP1B	356	Q8N612
DAADLLSPLALLRFS	MFSD10	241	Q14728
FSTPTLALATLRAED	DCHS1	1976	Q96JQ0
APLSQARSLFSLVAL	KLHL33	306	A6NCF5
RLGTLATALLAFPSV	MDN1	3431	Q9NU22
ALVVALIASTPALRT	GPR6	91	P46095
NVLLRFLDTQAPSLS	MED12L	571	Q86YW9
VALFSSVLALGITRP	DOLK	121	Q9UPQ8
RGFLLIAASISATPV	EYS	1446	Q5T1H1
ASDLLFTLSLPVRLS	LPAR5	66	Q9H1C0
TVALDRLFLPLSRVS	NLRC3	121	Q7RTR2
LPLFDSVRSTTALAL	INTS1	1036	Q8N201
SSLVQLLSAPEARTL	MTMR11	386	A4FU01
ATAPAVLQSLSLLFL	SLC2A10	171	O95528
LILSLRAVLASTPRF	MMS19	241	Q96T76
PFFLLLIDLSRASTL	HMGCR	126	P04035
IFSLAIALITSALLP	LMBRD1	51	Q9NUN5
DLPSALLFAASILTT	KCNK7	91	Q9Y2U2
RDVEALSPLIFLALS	SLC43A1	126	O75387
AAPTFLLLSSILGRA	CALHM2	96	Q9HA72
SPLTAVFSLSRSLLA	PCNX3	946	Q9H6A9
RLLSLVVSDAPDLSA	PLXNA2	576	O75051
VLLSTPALEAVFTDL	PDE4D	476	Q08499
RLVSLLALSQALPFE	BGN	6	P21810
SLLLPAESRSSVFAL	NDUFAF6	76	Q330K2
ATPARASSFLIENLL	HMX1	11	Q9NP08
LAAFLALVSVPRAQA	LCN6	6	P62502
RLSITLSCPLDLTLF	GLRB	176	P48167
SLSVAALAALPALRS	LRRC38	166	Q5VT99
AAALLSASPRALVTL	NLRP5	11	P59047
LIIAAFTATLLRAPS	PAQR6	311	Q6TCH4
SLADLSLLLFSAPIR	GPR151	81	Q8TDV0
PALTLRFLITQLEAA	DZIP3	101	Q86Y13
LALDSTRFPSQTLLL	LRRIQ1	1451	Q96JM4
LITRFLTPSELLFDL	NLRC5	266	Q86WI3
AFLLSTLFPLGELRS	PKD1L2	1441	Q7Z442
ALRQSFSSALVALVP	MEI1	1066	Q5TIA1
LADSLPVSRCSVALL	SBF1	201	O95248
LALADALATSTLPFQ	OPRD1	91	P41143
AAVPALSSDLLFIIS	PANX3	131	Q96QZ0
PGLLFLLFSSLRADT	ICOSLG	6	O75144
LPLETFSFLLTLLAT	GPR149	341	Q86SP6
APLESSSRVLISATL	OBSCN	7501	Q5VST9
RLPFLSSSNLSLDVL	POMP	91	Q9Y244
ASPDVLRTLAQISAL	ACP4	226	Q9BZG2
VVLPTLASLRIAAFE	PLCB3	786	Q01970
LPSAGDAFLTLRTLA	PBX4	316	Q9BYU1
LLVTLAARFPADFTA	HBZ	106	P02008
RASSIFPILSAILLL	CACNG8	126	Q8WXS5
LFLRSISEPALLEIF	FHIP1A	341	Q05DH4
SSNLPLRFLSTLIVL	CCDC138	486	Q96M89
LTVAAPNSALLARAL	C5AR2	256	Q9P296
IARSASLSSLLITPF	FNIP1	256	Q8TF40
AVLRSAALAPTSDLA	GGT6	256	Q6P531
PLLTALSAEAVASAL	CEP250	1231	Q9BV73
LSLTLLLPQADTRSF	GLB1L	16	Q6UWU2
LAVFLLDTSFLLSEP	ADGRG1	451	Q9Y653
LASTLLRAFPVNAAT	SLC25A29	251	Q8N8R3
PALTVLDVSFNRLTS	GP1BA	116	P07359
LDVSFNRLTSLPLGA	GP1BA	121	P07359
LPVSLLTAVALARLA	GPR142	171	Q7Z601
LSAPVTLNLRDLFST	MAN2B1	931	O00754
ISVDSRSVSLLPLEF	IL21R	176	Q9HBE5
NFISELAALARVPLA	EVC	901	P57679
LLDRNLSVLPESTLF	DNA2	546	P51530
TLSQDALLRISIPFD	SLC22A25	66	Q6T423
SLPATDAALIFVLTI	SPACA1	211	Q9HBV2
LASAVPSALLALAVF	SPACA6	6	W5XKT8
LPADLRLSISVIDSS	SACS	956	Q9NZJ4
ISSFADLLSSVLPRE	SACS	3211	Q9NZJ4
AASAQFVSRLLPVLL	IPO4	891	Q8TEX9
LLLAVFVTPLTDLRS	MSH2	431	P43246
LLSFLSAPLIGALSD	MFSD14C	91	Q5VZR4
LLSFLSAPLIGALSD	MFSD14B	91	Q5SR56
LLPTALLLVTTRAAA	NLRP6	316	P59044
LSSERDFALLSLQVP	C4A	76	P0C0L4
SAAATALSLLVPVFI	FOCAD	1041	Q5VW36
ATAFLSSEPRLDILI	DHRS13	106	Q6UX07
RLLSDIFIPALRATS	DNAH5	166	Q8TE73
SLLLNAASTVARPVF	RHOBTB3	41	O94955
TEALSCFLIPVLRSL	NUTM2D	281	Q5VT03
PRAVFSRILLLFSLT	FAN1	541	Q9Y2M0
LRLSVLVSLSFSFPL	TAS2R40	146	P59535
RFLLPSILSEFTALV	SZT2	2551	Q5T011
AFLATTELPARSIDL	HHLA1	61	C9JL84
IITPRLALTTAEFLA	ATP6V1B1	266	P15313
LPLLDSREISFQLSA	UTS2	21	O95399
ALLQSSGPERTALFI	MRPL44	201	Q9H9J2
SAFPEVRSLTLEALL	THADA	1551	Q6YHU6
SLIAIDRSFLSTLPG	POLR1A	366	O95602
ALAAVLLQALDRPAS	VGF	81	O15240
LVNSLDVLRAAAFSP	SH3BP4	941	Q9P0V3
SPFLNISALIALRIE	LRRC15	71	Q8TF66
SALTAIAVFLSLLPL	ABCC6	451	O95255
APVLISILLGASFSR	PTCHD1	31	Q96NR3
LDSVLSESLRLTAAP	PTGIS	341	Q16647
RLASILAPFSVDLSS	SLC22A16	486	Q86VW1
AAPALALVDLQLSAR	PKDREJ	106	Q9NTG1
ALLITEIFLQSSRPS	SLC2A5	396	P22732
LITATPRGTLLAFAE	NEU1	81	Q99519
DLSGTRLANFSLVPL	PRAMEF20	326	Q5VT98
TFLSCDSLTVLFLPR	RXFP2	276	Q8WXD0
RSSPAELTISALSLA	SLC26A10	196	Q8NG04
FERALPILNVALASL	TANC1	751	Q9C0D5
LSAVSSVLLSLPAAR	TELO2	771	Q9Y4R8
VDLDLSRPLFTSAAL	ORC6	131	Q9Y5N6
TAASPTIALLLEREA	SCRIB	936	Q14160
ALFVDRASSPILTLS	STARD9	3891	Q9P2P6
SIDPTLTRLFECLSL	MLXIPL	81	Q9NP71
LEARVSEPLLSATSA	MRTFA	141	Q969V6
PRASVFDLKAIASLL	SLC22A18	221	Q96BI1
LRLTSGAEILFAAPS	SPTBN5	3611	Q9NRC6
LNLPTSITSAAFTLR	ARID3A	301	Q99856
SADRFVTLLLPTILD	CIP2A	381	Q8TCG1
ASLAPRLASILTSAA	COASY	16	Q13057
AISDLLFISTLPFRA	CYSLTR2	81	Q9NS75
LLISSALLVLTSFPF	SLCO2A1	261	Q92959
LLAFLSASRDVLPRT	RINL	121	Q6ZS11
PLARALSAITAVSVA	PPOX	301	P50336
SRFATSLVDNSVPLL	RNF213	4416	Q63HN8
CPSLTLSEDARFLLI	WDR90	931	Q96KV7
STTVLALAFSPDDRL	WDR90	1206	Q96KV7
LRFALASLLQSAPDV	ZSWIM9	271	Q86XI8
LLLSRQAPSLAFSVT	TLCD2	151	A6NGC4
LAALSASLARVVVPA	PES1	276	O00541
PSLLTFLDLSRNLLE	PHLPP2	501	Q6ZVD8
TSAAAFRGLLLLLPS	SLC52A1	206	Q9NWF4
SLEFFLEAPSVLLSI	SLC35A5	356	Q9BS91
TLALVLATFDPARGT	STC2	11	O76061
LSSVLNELPSAATLR	TMC4	36	Q7Z404
LSANASRDIIILFTP	TMEM131	1056	Q92545
FFSESLGIPSLRVLA	TMEM53	76	Q6P2H8
LLESAFADTLTPARL	NEURL1B	191	A8MQ27
QLRASVFALALPLSL	TMEM44	131	Q2T9K0
LSASTVPLTFLLVDR	RFPL3	226	O75679
FLEQRLAAPLLGSSS	USP20	91	Q9Y2K6
LLEIARSLDSFLLSP	TNPO3	541	Q9Y5L0
FLLRPSDLQSILSDA	TRPV3	506	Q8NET8
LSSTGPVLVFERLLF	SLC4A4	526	Q9Y6R1
ARFLAAFTLPALLAT	SNAPC4	1366	Q5SXM2
FTLSTEAISLIPREA	STRCP1	1391	A6NGW2
FLSPRLSLATVLLVF	TEX28	331	O15482
RLLDITPASSLSFVL	VWA7	306	Q9Y334
SALPALLFTASFLLL	TMEM239	156	Q8WW34
ALSLGELALSFSRVP	TMEM38A	6	Q9H6F2
DLSLISPLAQAVRSS	TNF	66	P01375
LSFQTAARILASPVE	UGGT1	326	Q9NYU2
SFADSAVAPLALEIL	ULK4	1256	Q96C45
PFASLASRLTLAELN	AGL	891	P35573
LLFSRLFEVITLSGP	MYO7B	1406	Q6PIF6