Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionintramolecular oxidoreductase activity, transposing S-S bonds

PDIA4 P4HB PDIA5 PDIA3

5.29e-0922204GO:0016864
GeneOntologyMolecularFunctionprotein disulfide isomerase activity

PDIA4 P4HB PDIA5 PDIA3

5.29e-0922204GO:0003756
GeneOntologyMolecularFunctionprotein-disulfide reductase activity

PDIA4 P4HB PDIA5 PDIA3

4.22e-0836204GO:0015035
GeneOntologyMolecularFunctiondisulfide oxidoreductase activity

PDIA4 P4HB PDIA5 PDIA3

8.81e-0843204GO:0015036
GeneOntologyMolecularFunctionintramolecular oxidoreductase activity

PDIA4 P4HB PDIA5 PDIA3

2.79e-0757204GO:0016860
GeneOntologyMolecularFunctionoxidoreductase activity, acting on a sulfur group of donors

PDIA4 P4HB PDIA5 PDIA3

2.79e-0757204GO:0016667
GeneOntologyMolecularFunctionisomerase activity

PDIA4 P4HB PDIA5 PDIA3

3.56e-05192204GO:0016853
GeneOntologyMolecularFunctionintegrin binding

PDIA4 P4HB ADAM20

6.76e-04175203GO:0005178
GeneOntologyMolecularFunctioncell adhesion molecule binding

PDIA4 P4HB ADAM20 PDLIM5

2.65e-03599204GO:0050839
GeneOntologyBiologicalProcesspositive regulation of protein folding

PDIA4 PDIA3

8.92e-065202GO:1903334
GeneOntologyBiologicalProcessprotein folding in endoplasmic reticulum

P4HB PDIA3

6.92e-0513202GO:0034975
GeneOntologyBiologicalProcessregulation of protein folding

PDIA4 PDIA3

8.07e-0514202GO:1903332
GeneOntologyBiologicalProcessprotein folding

PDIA4 P4HB PDIA5 PDIA3

8.23e-05246204GO:0006457
GeneOntologyBiologicalProcesscellular response to interleukin-7

P4HB PDIA3

1.86e-0421202GO:0098761
GeneOntologyBiologicalProcessresponse to interleukin-7

P4HB PDIA3

2.04e-0422202GO:0098760
GeneOntologyCellularComponentendoplasmic reticulum chaperone complex

PDIA4 P4HB

6.74e-0513202GO:0034663
GeneOntologyCellularComponentpigment granule

PDIA4 P4HB PDIA3

1.64e-04113203GO:0048770
GeneOntologyCellularComponentmelanosome

PDIA4 P4HB PDIA3

1.64e-04113203GO:0042470
GeneOntologyCellularComponentendoplasmic reticulum protein-containing complex

PDIA4 P4HB PDIA3

2.21e-04125203GO:0140534
GeneOntologyCellularComponentendoplasmic reticulum lumen

PDIA4 P4HB PDIA5 PDIA3

2.48e-04332204GO:0005788
GeneOntologyCellularComponentsmooth endoplasmic reticulum

PDIA4 PDIA3

8.78e-0446202GO:0005790
GeneOntologyCellularComponentcell surface

PDIA4 P4HB PDIA3 ADAM20 SCUBE2

3.34e-031111205GO:0009986
HumanPhenoFlexion contracture of finger

NSD1 RNF13 SCN4A

3.99e-0424043HP:0005651
HumanPhenoCamptodactyly (hands)

NSD1 RNF13 SCN4A

3.99e-0424043HP:0010563
HumanPhenoCamptodactyly of toe

NSD1 RNF13 SCN4A

3.99e-0424043HP:0001836
HumanPhenoJoint contractures involving the joints of the feet

NSD1 RNF13 SCN4A

3.99e-0424043HP:0100492
HumanPhenoCamptodactyly of finger

NSD1 RNF13 SCN4A

3.99e-0424043HP:0100490
HumanPhenoFlexion contracture of toe

NSD1 RNF13 SCN4A

3.99e-0424043HP:0005830
HumanPhenoInterphalangeal joint contracture of finger

NSD1 RNF13 SCN4A

3.99e-0424043HP:0001220
HumanPhenoToe joint contracture

NSD1 RNF13 SCN4A

4.04e-0424143HP:0034675
HumanPhenoFlexion contracture of finger

NSD1 RNF13 SCN4A

4.89e-0425743HP:0012785
HumanPhenoFinger joint contracture

NSD1 RNF13 SCN4A

5.00e-0425943HP:0034681
HumanPhenoAbnormal phalangeal joint morphology of the hand

NSD1 RNF13 SCN4A

5.18e-0426243HP:0006261
HumanPhenoPedal edema

NSD1 RNF13

6.53e-045442HP:0010741
HumanPhenoExpressive language delay

NSD1 SCN4A

7.02e-045642HP:0002474
HumanPhenoLanguage delay

NSD1 SCN4A

7.02e-045642HP:0002336
HumanPhenoJoint contractures

NSD1 RNF13 SCN4A

7.14e-0429243HP:0001372
HumanPhenoJoint contracture of the hand

NSD1 RNF13 SCN4A

7.44e-0429643HP:0009473
HumanPhenoAbnormal pitch

NSD1 P4HB

8.06e-046042HP:5200005
HumanPhenoHip contracture

NSD1 SCN4A

8.61e-046242HP:0003273
HumanPhenoFoot joint contracture

NSD1 RNF13 SCN4A

1.06e-0333443HP:0008366
HumanPhenoAbnormal Intonation

NSD1 P4HB

1.07e-036942HP:5200010
HumanPhenoCamptodactyly

NSD1 RNF13 SCN4A

1.18e-0334643HP:0012385
HumanPhenoUpper-limb joint contracture

NSD1 RNF13 SCN4A

1.35e-0336243HP:0100360
HumanPhenoFlexion contracture of digit

NSD1 RNF13 SCN4A

1.35e-0336243HP:0030044
HumanPhenoLimited hip movement

NSD1 SCN4A

1.36e-037842HP:0008800
HumanPhenoAbnormal prosody

NSD1 P4HB

1.50e-038242HP:0031434
HumanPhenoAbnormality of the dentition

NSD1 P4HB RNF13 SCN4A

1.66e-03103044HP:0000164
HumanPhenoLower-limb joint contracture

NSD1 RNF13 SCN4A

1.85e-0340343HP:0005750
HumanPhenoScoliosis

NSD1 P4HB RNF13 SCN4A

2.34e-03112244HP:0002650
DomainDisulphide_isomerase

PDIA4 P4HB PDIA5 PDIA3

6.67e-118204IPR005788
DomainThioredoxin

PDIA4 P4HB PDIA5 PDIA3

6.79e-1013204IPR005746
DomainThioredoxin_CS

PDIA4 P4HB PDIA5 PDIA3

2.25e-0917204IPR017937
DomainProt_disulphide_isomerase

PDIA4 P4HB PDIA3

4.20e-094203IPR005792
DomainTHIOREDOXIN_1

PDIA4 P4HB PDIA5 PDIA3

1.19e-0825204PS00194
DomainThioredoxin

PDIA4 P4HB PDIA5 PDIA3

2.95e-0831204PF00085
DomainThioredoxin_domain

PDIA4 P4HB PDIA5 PDIA3

9.44e-0841204IPR013766
DomainTHIOREDOXIN_2

PDIA4 P4HB PDIA5 PDIA3

1.15e-0743204PS51352
Domain-

PDIA4 P4HB PDIA5 PDIA3

7.74e-061222043.40.30.10
DomainThioredoxin-like_fold

PDIA4 P4HB PDIA5 PDIA3

1.06e-05132204IPR012336
DomainER_TARGET

PDIA4 P4HB PDIA5

1.65e-0547203PS00014
DomainPWWP

NSD1 ZMYND8

2.05e-0420202SM00293
DomainPWWP

NSD1 ZMYND8

2.72e-0423202PF00855
DomainPWWP_dom

NSD1 ZMYND8

2.72e-0423202IPR000313
DomainPWWP

NSD1 ZMYND8

2.96e-0424202PS50812
DomainZinc_finger_PHD-type_CS

NSD1 ZMYND8

2.18e-0365202IPR019786
DomainPHD

NSD1 ZMYND8

2.88e-0375202PF00628
DomainZnf_PHD-finger

NSD1 ZMYND8

3.19e-0379202IPR019787
DomainPHD

NSD1 ZMYND8

4.03e-0389202SM00249
DomainZnf_PHD

NSD1 ZMYND8

4.21e-0391202IPR001965
DomainZF_PHD_2

NSD1 ZMYND8

4.58e-0395202PS50016
DomainZF_PHD_1

NSD1 ZMYND8

4.68e-0396202PS01359
DomainZnf_FYVE_PHD

NSD1 ZMYND8

1.07e-02147202IPR011011
Domain-

NSD1 RNF13 ZMYND8

1.16e-024492033.30.40.10
DomainZnf_RING/FYVE/PHD

NSD1 RNF13 ZMYND8

1.23e-02459203IPR013083
Pubmed

pH dependence of the peptide thiol-disulfide oxidase activity of six members of the human protein disulfide isomerase family.

PDIA4 P4HB PDIA5 PDIA3

1.19e-12620416677074
Pubmed

Glycosaminoglycans and protein disulfide isomerase-mediated reduction of HIV Env.

PDIA4 P4HB PDIA5 PDIA3

1.19e-12620415644496
Pubmed

Stability of a receptor-binding active human immunodeficiency virus type 1 recombinant gp140 trimer conferred by intermonomer disulfide bonding of the V3 loop: differential effects of protein disulfide isomerase on CD4 and coreceptor binding.

PDIA4 P4HB PDIA5 PDIA3

2.78e-12720417301129
Pubmed

Snapshot of the interaction between HIV envelope glycoprotein 120 and protein disulfide isomerase.

PDIA4 P4HB PDIA5 PDIA3

2.78e-12720420458450
Pubmed

Inhibitors of protein-disulfide isomerase prevent cleavage of disulfide bonds in receptor-bound glycoprotein 120 and prevent HIV-1 entry.

PDIA4 P4HB PDIA5 PDIA3

2.78e-12720412218051
Pubmed

Cell-type specific requirements for thiol/disulfide exchange during HIV-1 entry and infection.

PDIA4 P4HB PDIA5 PDIA3

2.78e-12720423206338
Pubmed

Protein-disulfide isomerase-mediated reduction of two disulfide bonds of HIV envelope glycoprotein 120 occurs post-CXCR4 binding and is required for fusion.

PDIA4 P4HB PDIA5 PDIA3

5.56e-12820412218052
Pubmed

Proteins of the PDI family: unpredicted non-ER locations and functions.

PDIA4 P4HB PDIA5 PDIA3

5.56e-12820412384992
Pubmed

Elevated expression of PDI family proteins during differentiation of mouse F9 teratocarcinoma cells.

PDIA4 P4HB PDIA3

1.63e-1032039493907
Pubmed

Progress in targeting HIV-1 entry.

PDIA4 PDIA5 PDIA3

1.62e-09520316182193
Pubmed

Disulphide production by Ero1α-PDI relay is rapid and effectively regulated.

PDIA4 P4HB PDIA3

3.25e-09620320802462
Pubmed

Thioredoxin-1 and protein disulfide isomerase catalyze the reduction of similar disulfides in HIV gp120.

PDIA4 PDIA5 PDIA3

9.09e-09820322230366
Pubmed

Mapping of three members of the mouse protein disulfide isomerase family.

PDIA4 P4HB PDIA3

3.57e-08122039457688
Pubmed

Mapping wild-type and R345W fibulin-3 intracellular interactomes.

PDIA4 P4HB PDIA3

2.49e-072220327777122
Pubmed

Functions of characteristic Cys-Gly-His-Cys (CGHC) and Gln-Glu-Asp-Leu (QEDL) motifs of microsomal ER-60 protease.

P4HB PDIA3

3.14e-0722029399589
Pubmed

ERp72, an abundant luminal endoplasmic reticulum protein, contains three copies of the active site sequences of protein disulfide isomerase.

PDIA4 P4HB

3.14e-0722022295602
Pubmed

P4HB and PDIA3 are associated with tumor progression and therapeutic outcome of diffuse gliomas.

P4HB PDIA3

3.14e-07220229207176
Pubmed

ALS-linked protein disulfide isomerase variants cause motor dysfunction.

P4HB PDIA3

3.14e-07220226869642
Pubmed

Proteomic analysis of early melanosomes: identification of novel melanosomal proteins.

PDIA4 P4HB PDIA3

5.89e-072920312643545
Pubmed

Regulation of perforin lysis: implications for protein disulfide isomerase proteins.

P4HB PDIA3

9.42e-07320219147124
Pubmed

A PDI family network acts distinctly and coordinately with ERp29 to facilitate polyomavirus infection.

PDIA4 PDIA3

9.42e-07320221159867
Pubmed

The C-terminal CGHC motif of protein disulfide isomerase supports thrombosis.

P4HB PDIA3

9.42e-07320226529254
Pubmed

An interaction map of endoplasmic reticulum chaperones and foldases.

PDIA4 PDIA3

1.88e-06420222665516
Pubmed

KDEL Receptor 1 Contributes to Cell Surface Association of Protein Disulfide Isomerases.

P4HB PDIA3

1.88e-06420230958660
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

NSD1 P4HB PDIA3 ADAM20 USP4 GALNT1

2.53e-0673020634857952
Pubmed

Recycling of peroxiredoxin IV provides a novel pathway for disulphide formation in the endoplasmic reticulum.

P4HB PDIA3

3.14e-06520221057456
Pubmed

ERp57 functions as a subunit of specific complexes formed with the ER lectins calreticulin and calnexin.

P4HB PDIA3

3.14e-06520210436013
Pubmed

Transient covalent interactions of newly synthesized thyroglobulin with oxidoreductases of the endoplasmic reticulum.

PDIA4 PDIA3

3.14e-06520224599957
Pubmed

Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein-Protein Interaction Data.

PDIA4 P4HB PDIA3

3.53e-065220326499835
Pubmed

Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation.

PDIA4 PDIA3

4.71e-06620219995400
Pubmed

The disulfide isomerase ERp72 supports arterial thrombosis in mice.

PDIA4 PDIA3

4.71e-06620228576878
Pubmed

Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing.

P4HB PDIA3

1.13e-05920217055437
Pubmed

Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry.

P4HB PDIA3

1.13e-05920221670307
Pubmed

Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.

PDIA4 P4HB PDIA3

1.25e-057920317081065
Pubmed

SUMOylation of ERp44 enhances Ero1α ER retention contributing to the pathogenesis of obesity and insulin resistance.

P4HB PDIA3

1.72e-051120236427672
Pubmed

A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins.

PDIA4 P4HB

2.85e-051420212475965
Pubmed

A two-dimensional gel database of human colon carcinoma proteins.

P4HB PDIA3

3.28e-05152029150948
Pubmed

A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.

PDIA4 P4HB

3.28e-051520234487921
Pubmed

The human protein disulfide isomerase gene family.

PDIA4 PDIA5

3.75e-051620223245351
Pubmed

Development of a deer mouse whole-genome radiation hybrid panel and comparative mapping of Mus chromosome 11 loci.

P4HB SCN4A

4.78e-051820216416089
Pubmed

IL-7-induced phosphorylation of the adaptor Crk-like and other targets.

P4HB PDIA3

5.34e-051920229581031
Pubmed

PKCε promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria.

PDIA4 P4HB PDIA3

6.35e-0513620322304920
Pubmed

Ubiquitin-protein ligase E3C maintains non-small-cell lung cancer stemness by targeting AHNAK-p53 complex.

P4HB PDIA3

6.55e-052120230503554
Pubmed

Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.

PDIA4 P4HB PDIA3

8.33e-0514920326370502
Pubmed

ERp57 is essential for efficient folding of glycoproteins sharing common structural domains.

PDIA4 PDIA3

9.35e-052520217170699
Pubmed

Human liver protein map: a reference database established by microsequencing and gel comparison.

P4HB PDIA3

1.18e-04282021286669
Pubmed

Global landscape of HIV-human protein complexes.

PDIA4 P4HB PDIA5 PDIA3

1.21e-0445720422190034
Pubmed

Phosphorylation switches protein disulfide isomerase activity to maintain proteostasis and attenuate ER stress.

P4HB PDIA5 PDIA3

1.32e-0417420332149426
Pubmed

MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1.

PDIA4 P4HB PDIA3

1.50e-0418220330711629
Pubmed

A Chemical Proteomics Approach to Reveal Direct Protein-Protein Interactions in Living Cells.

P4HB PDIA3

1.85e-043520229104064
Pubmed

Evolutionarily conserved regulators of tau identify targets for new therapies.

PDIA4 P4HB PDIA3 RNF13

1.92e-0451620436610398
Pubmed

Galectin-8 Senses Phagosomal Damage and Recruits Selective Autophagy Adapter TAX1BP1 To Control Mycobacterium tuberculosis Infection in Macrophages.

PDIA4 P4HB

2.07e-043720234225486
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

PDIA4 P4HB PDIA5 PDIA3 GALNT1

2.17e-04100720534597346
Pubmed

IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5.

P4HB PDIA3 PDLIM5

2.66e-0422120331950832
Pubmed

LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.

PDIA4 P4HB PDIA3 PDLIM5

3.00e-0458020435676659
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

PDIA4 NSD1 P4HB ZNF182 GALNT1

3.06e-04108420511544199
Pubmed

Parkinson's disease-associated LRRK2-G2019S mutant acts through regulation of SERCA activity to control ER stress in astrocytes.

PDIA4 P4HB PDIA3

4.14e-0425720331046837
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

PDIA4 P4HB PDIA5 PDIA3 GALNT1

4.90e-04120120535696571
Pubmed

Inhibition of N-glycan processing modulates the network of EDEM3 interactors.

PDIA4 PDIA3

4.92e-045720228366632
Pubmed

Protein profiling of human pancreatic islets by two-dimensional gel electrophoresis and mass spectrometry.

P4HB PDIA3

5.09e-045820215952740
Pubmed

Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network.

PDIA4 P4HB PDIA3

5.43e-0428220335007762
InteractionCALR3 interactions

PDIA4 P4HB PDIA5 PDIA3

1.05e-05142204int:CALR3
InteractionERO1B interactions

PDIA4 P4HB PDIA3

2.12e-0555203int:ERO1B
InteractionDNAJB14 interactions

PDIA4 P4HB PDIA3

3.68e-0566203int:DNAJB14
InteractionDNAJC18 interactions

PDIA4 P4HB PDIA3

5.39e-0575203int:DNAJC18
InteractionDNAJC30 interactions

PDIA4 P4HB PDIA3 SCN4A

5.53e-05217204int:DNAJC30
InteractionDNAJC3 interactions

PDIA4 P4HB PDIA3 SCN4A

6.48e-05226204int:DNAJC3
InteractionDNAJC16 interactions

PDIA4 P4HB PDIA3 SCN4A

7.29e-05233204int:DNAJC16
InteractionPLD4 interactions

PDIA4 P4HB PDIA3

7.30e-0583203int:PLD4
InteractionEPHA10 interactions

PDIA4 P4HB PDIA3

8.12e-0586203int:EPHA10
InteractionMTTP interactions

PDIA4 P4HB

1.58e-0419202int:MTTP
InteractionPTPRN interactions

PDIA4 P4HB PDIA3

2.02e-04117203int:PTPRN
InteractionEDEM3 interactions

PDIA4 P4HB PDIA3

2.02e-04117203int:EDEM3
InteractionTMEM106B interactions

PDIA4 P4HB PDIA5 PDIA3

2.16e-04309204int:TMEM106B
InteractionIDS interactions

PDIA4 PDIA5 PDIA3

2.18e-04120203int:IDS
InteractionHSPA13 interactions

PDIA4 P4HB PDIA3

2.29e-04122203int:HSPA13
InteractionEFEMP1 interactions

PDIA4 P4HB PDIA3

2.34e-04123203int:EFEMP1
InteractionPTPRU interactions

PDIA4 P4HB PDIA3

2.40e-04124203int:PTPRU
InteractionSDF2L1 interactions

PDIA4 P4HB PDIA5 PDIA3

2.53e-04322204int:SDF2L1
InteractionPDIA6 interactions

PDIA4 P4HB PDIA5 PDIA3

2.68e-04327204int:PDIA6
InteractionERO1A interactions

PDIA4 P4HB PDIA3

2.89e-04132203int:ERO1A
InteractionCALU interactions

PDIA4 P4HB PDIA3 PDLIM5

2.98e-04336204int:CALU
InteractionERN2 interactions

PDIA4 P4HB

3.00e-0426202int:ERN2
InteractionANP32A interactions

PDIA4 PDIA3 PDLIM5

3.02e-04134203int:ANP32A
InteractionPLIN3 interactions

P4HB USP4 PDLIM5

3.36e-04139203int:PLIN3
InteractionDNAJB11 interactions

PDIA4 P4HB PDIA5 PDIA3

3.51e-04351204int:DNAJB11
InteractionTKT interactions

PDIA4 ABHD14B P4HB PDIA3

3.59e-04353204int:TKT
InteractionPTPRO interactions

PDIA4 P4HB PDIA3

3.65e-04143203int:PTPRO
InteractionERP27 interactions

PDIA5 PDIA3

4.00e-0430202int:ERP27
InteractionTCTN1 interactions

PDIA4 P4HB PDIA3

4.28e-04151203int:TCTN1
InteractionVWF interactions

PDIA4 P4HB

4.56e-0432202int:VWF
InteractionPPME1 interactions

PDIA4 P4HB PDIA3

4.71e-04156203int:PPME1
InteractionMAP3K7 interactions

PDIA4 P4HB PDIA3 USP4

4.75e-04380204int:MAP3K7
InteractionACP5 interactions

P4HB PDIA3

5.15e-0434202int:ACP5
InteractionCDPF1 interactions

USP4 PDLIM5

6.10e-0437202int:CDPF1
InteractionPRKCZ interactions

PDIA4 P4HB PDIA3 BRSK1

6.43e-04412204int:PRKCZ
InteractionLGALS8 interactions

PDIA4 P4HB RNF13

6.47e-04174203int:LGALS8
InteractionDNAJB12 interactions

PDIA4 P4HB PDIA3

6.47e-04174203int:DNAJB12
InteractionLDLR interactions

PDIA4 P4HB PDIA5 PDIA3

6.73e-04417204int:LDLR
InteractionNTM interactions

P4HB PDIA5

7.14e-0440202int:NTM
InteractionPLOD2 interactions

PDIA4 P4HB PDIA3

7.14e-04180203int:PLOD2
InteractionFAM20C interactions

P4HB PDIA5 PDIA3

8.10e-04188203int:FAM20C
InteractionSYNE3 interactions

PDIA4 P4HB PDIA5 PDIA3

8.51e-04444204int:SYNE3
InteractionERP44 interactions

PDIA4 P4HB PDIA3

8.87e-04194203int:ERP44
InteractionMST1R interactions

PDIA4 P4HB PDIA3

9.69e-04200203int:MST1R
InteractionDNAJB9 interactions

PDIA4 P4HB PDIA3

9.97e-04202203int:DNAJB9
InteractionPDIA4 interactions

PDIA4 P4HB PDIA5 PDIA3

1.04e-03468204int:PDIA4
InteractionLAIR2 interactions

PDIA4 PDIA5

1.07e-0349202int:LAIR2
InteractionMTSS2 interactions

PDIA4 P4HB

1.07e-0349202int:MTSS2
InteractionCOL12A1 interactions

PDIA4 PDIA3

1.11e-0350202int:COL12A1
InteractionPRDX4 interactions

PDIA4 P4HB PDIA3

1.18e-03214203int:PRDX4
CytobandEnsembl 112 genes in cytogenetic band chr3p21

ABHD14B USP4

8.27e-03316202chr3p21
GeneFamilyProtein disulfide isomerases

PDIA4 P4HB PDIA5 PDIA3

3.17e-0921174692
GeneFamilyPWWP domain containing

NSD1 ZMYND8

1.90e-04221721147
GeneFamilyPHD finger proteins

NSD1 ZMYND8

3.17e-039017288
GeneFamilyRing finger proteins

RNF217 RNF13

2.70e-0227517258
CoexpressionGSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_UP

PDIA4 NSD1 P4HB PDIA3 BTG1

3.48e-07200205M5783
CoexpressionGSE8621_UNSTIM_VS_LPS_STIM_MACROPHAGE_UP

RNF217 ABHD14B P4HB BRSK1

1.42e-05199204M6970
CoexpressionGSE9006_TYPE_1_DIABETES_AT_DX_VS_4MONTH_POST_DX_PBMC_UP

PDIA4 NSD1 P4HB PDIA3

1.45e-05200204M5787
CoexpressionTIEN_INTESTINE_PROBIOTICS_24HR_DN

PDIA4 P4HB PDIA3 BTG1

1.92e-05215204M19666
CoexpressionZHANG_UTERUS_C2_SECRETORY_STROMAL3_RAMP3_HIGH_CELL

CRISPLD2 P4HB PDIA3 BTG1

2.46e-05229204MM16607
CoexpressionZHANG_UTERUS_C1_PROLIFERATIVE_STROMAL1_MGP_HIGH_CELL

CRISPLD2 P4HB PDIA3 BTG1

8.01e-05310204MM16608
CoexpressionSUZUKI_RESPONSE_TO_TSA

PDIA5 ZMYND8

8.40e-0518202M1680
CoexpressionZHANG_UTERUS_C0_SECRETORY_STROMAL3_NPPC_HIGH_CELL

CRISPLD2 P4HB PDIA3 BTG1

1.11e-04337204MM16606
CoexpressionWAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP

PDIA4 PDIA5 PDIA3

1.59e-04140203M2435
CoexpressionTRAVAGLINI_LUNG_GOBLET_CELL

PDIA4 P4HB PDLIM5

1.87e-04148203M41655
CoexpressionCHEN_LUNG_CANCER_SURVIVAL

P4HB PDIA5

2.07e-0428202M8526
CoexpressionNAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP

PDIA5 RNF13 USP4 BTG1 ZMYND8 GALNT1

2.17e-041215206M41122
CoexpressionOSMAN_BLADDER_CANCER_UP

P4HB PDIA3 PDLIM5 GALNT1

2.17e-04402204M5275
CoexpressionYAMAZAKI_TCEB3_TARGETS_UP

INTS6L P4HB PDIA3

2.63e-04166203M1542
CoexpressionGSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_NOD_DN

NSD1 PDLIM5 SCN4A

2.87e-04171203M8820
CoexpressionJOHNSTONE_PARVB_TARGETS_3_UP

CRISPLD2 ABHD14B P4HB BTG1

2.88e-04433204M2240
CoexpressionYAMAZAKI_TCEB3_TARGETS_UP

INTS6L P4HB PDIA3

3.28e-04179203MM660
CoexpressionMILI_PSEUDOPODIA_CHEMOTAXIS_DN

PDIA5 PDIA3 BTG1 ZMYND8

3.54e-04457204M1613
CoexpressionMILI_PSEUDOPODIA_CHEMOTAXIS_DN

PDIA5 PDIA3 BTG1 ZMYND8

3.94e-04470204MM1053
CoexpressionGSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_DN

PDIA4 CRISPLD2 PDIA5

4.21e-04195203M8502
CoexpressionGSE39556_CD8A_DC_VS_NK_CELL_DN

PDIA5 RNF13 BTG1

4.40e-04198203M9407
CoexpressionGSE13411_NAIVE_VS_SWITCHED_MEMORY_BCELL_DN

P4HB ADAM20 ZMYND8

4.40e-04198203M3242
CoexpressionGSE22033_UNTREATED_VS_ROSIGLITAZONE_TREATED_MEF_DN

USP4 BTG1 GALNT1

4.47e-04199203M7690
CoexpressionGSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_UP

PDIA5 RNF13 SCN4A

4.47e-04199203M9420
CoexpressionGSE5503_MLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_UP

INTS6L RNF217 ABHD14B

4.53e-04200203M293
CoexpressionGSE43260_BTLA_POS_VS_NEG_INTRATUMORAL_CD8_TCELL_UP

PDIA4 P4HB PDIA3

4.53e-04200203M9953
CoexpressionGSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_UP

RNF13 USP4 GALNT1

4.53e-04200203M5131
CoexpressionGSE7509_DC_VS_MONOCYTE_DN

PDIA5 PDIA3 GALNT1

4.53e-04200203M6829
CoexpressionGSE23398_WT_VS_IL2_KO_CD4_TCELL_SCURFY_MOUSE_DN

PDIA3 BTG1 ZMYND8

4.53e-04200203M8079
CoexpressionGSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY7_UP

PDIA5 PDIA3 USP4

4.53e-04200203M9336
CoexpressionGSE21546_WT_VS_SAP1A_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP

RNF217 P4HB PDIA5

4.53e-04200203M7519
CoexpressionGSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_1MONTH_POST_DX_UP

PDIA4 PDIA3 GALNT1

4.53e-04200203M5777
CoexpressionGSE36826_WT_VS_IL1R_KO_SKIN_STAPH_AUREUS_INF_UP

P4HB PDIA5 PDLIM5

4.53e-04200203M9536
CoexpressionGRUETZMANN_PANCREATIC_CANCER_DN

P4HB PDIA5 BTG1

4.53e-04200203M10431
CoexpressionCHANDRAN_METASTASIS_UP

NSD1 PDLIM5 ZMYND8

5.15e-04209203M16036
CoexpressionVANTVEER_BREAST_CANCER_METASTASIS_UP

PDIA4 SCUBE2

5.37e-0445202M500
CoexpressionPELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN

PDIA5 PDIA3

6.37e-0449202M8341
CoexpressionBLUM_RESPONSE_TO_SALIRASIB_UP

P4HB RNF13 BTG1

8.18e-04245203M7300
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA3 RNF13 BTG1

2.08e-081942052224c7c943cfd5c1a329dfcf19d6e5ef8c49d85d
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA3 RNF13 BTG1

2.08e-0819420550c5fc349533281a426bc7227a8ea9eca8d11985
ToppCellfacs-Brain_Myeloid-Cortex-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA3 RNF13 BTG1

2.08e-081942051662b110f84584e75150df0ac970e7df82f26e7e
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA3 RNF13 BTG1

2.08e-08194205b31d6361fa939a92a4a3dc63c209ecd3eb514e6a
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B_plasma-Plasma_cells|lymph-node_spleen / Manually curated celltypes from each tissue

PDIA4 P4HB PDIA5 BRSK1

1.22e-06183204a6866951866373a1029e04818f4a4a31278c409d
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA5 PDIA3

1.22e-06183204e32847cfebba7c8bb2026e33c3c85f64819460a9
ToppCelldroplet-Marrow-nan-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA5 PDIA3

1.22e-06183204b5782b18decfe85026acf42daac0670d92385861
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B_plasma|lymph-node_spleen / Manually curated celltypes from each tissue

PDIA4 P4HB PDIA5 BRSK1

1.22e-06183204beadc69f511cf183e493cb445135f0748ab8b20e
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA5 PDIA3

1.36e-061882047e27e49ec1eb02fb74c86ec2ccb84751bc778b21
ToppCellfacs-SCAT-Fat-3m|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA3 GALNT1

1.36e-06188204b8dff61240e5052c2fbf7f28b86fe41822df45b0
ToppCelldroplet-Marrow-nan-21m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA5 PDIA3

1.36e-061882044b14c3ad80507245564d5be96d33fd9361f67dd0
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA3 RNF13

1.39e-061892046dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA3 RNF13

1.39e-061892043ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA3 RNF13

1.39e-06189204875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCellfacs-Brain_Myeloid-Striatum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA3 RNF13

1.39e-0618920497ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCelldroplet-Marrow-nan-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA5 PDIA3

1.42e-06190204240923769fef18eaf73d2efa3d5f745f5533b0ce
ToppCellmetastatic_Lymph_Node-B_lymphocytes-MALT_B_cells|B_lymphocytes / Location, Cell class and cell subclass

PDIA4 P4HB PDIA5 BRSK1

1.42e-061902045ec49cc7692053c1a525ca9137c996ccd2794e1c
ToppCellnormal_Lymph_Node-B_lymphocytes-MALT_B_cells|normal_Lymph_Node / Location, Cell class and cell subclass

PDIA4 P4HB PDIA5 BRSK1

1.42e-061902041f907016980ccfbf089e354d91d931771e8a83e0
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA5 PDIA3

1.42e-061902049df9b9e91c97e504c189d6055a6aabc54ad17cec
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PDIA4 P4HB PDIA3 BTG1

1.45e-06191204cf217d00ba2b0402a8e72fcd64bdb36d5539dde0
ToppCellnormal_Lymph_Node-B_lymphocytes-MALT_B_cells|B_lymphocytes / Location, Cell class and cell subclass

PDIA4 P4HB PDIA5 BRSK1

1.54e-061942041ca034f25a8fce503fb67654d7fa2a8ec71976be
ToppCelltumor_Lung-B_lymphocytes-MALT_B_cells|B_lymphocytes / Location, Cell class and cell subclass

PDIA4 P4HB PDIA5 BRSK1

1.60e-061962041f63dba9d226e4a42d9bee7258580a1e547c0e92
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INTS6L RNF217 CRISPLD2

6.07e-051732032acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INTS6L RNF217 CRISPLD2

6.07e-051732032415b6ff49f334da570577d4e93484d024a3dbd5
ToppCelldroplet-Marrow-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 RNF13 BTG1

6.17e-05174203a188ec192c378f731af1c95eb8f1392a2bb18c26
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INTS6L RNF217 CRISPLD2

6.61e-051782037467e5ab2fcb39cc4a2c7dd69722c91def3b6aea
ToppCellILEUM-non-inflamed-(5)_Plasmablasts|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PDIA4 P4HB PDIA5

6.72e-0517920358c8996120637315dcbd1991a71516c09173051e
ToppCellnormal-na-Lymphocytic_NK-T_mait-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

P4HB PDIA3 BTG1

6.83e-05180203e66a8a61b3576ac37de7c559d16d4ed4f7a2fc78
ToppCellCOVID-19-Epithelial-Ionocytes|Epithelial / Condition, Lineage and Cell class

INTS6L SCUBE2 BRSK1

6.94e-051812034a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCellILEUM-inflamed-(5)_IgA_plasma_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PDIA4 P4HB BRSK1

7.17e-05183203a113558ca4220bac31f9336033dff82a618d9258
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDIA4 P4HB PDIA5

7.29e-05184203af6522586d012e91241f3e06c60f9d1881e95646
ToppCell10x5'-Liver-Lymphocytic_B_plasma-Plasma_cells|Liver / Manually curated celltypes from each tissue

PDIA4 P4HB PDIA5

7.29e-051842036f70d8f8ab8362d51f8a58735d42223e06566397
ToppCell10x5'-GI_large-bowel-Lymphocytic_B_plasma-Plasma_cells|GI_large-bowel / Manually curated celltypes from each tissue

PDIA4 P4HB PDIA5

7.41e-051852032cad994207c4afc9d70f4c2d243ffbbcdbba693e
ToppCellmetastatic_Lymph_Node-B_lymphocytes-MALT_B_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

PDIA4 PDIA5 BRSK1

7.41e-05185203bb87fa174f80706fe7be60d3b9fc3e2a6b373038
ToppCell10x5'-GI_large-bowel-Lymphocytic_B_plasma|GI_large-bowel / Manually curated celltypes from each tissue

PDIA4 P4HB PDIA5

7.41e-05185203989583c487d8c121e3731faf68f863ba43a582e6
ToppCellILEUM-non-inflamed-(5)_IgG_plasma_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PDIA4 P4HB BRSK1

7.41e-0518520393b9a47357152ea95dfdfe8e7d111906a4adc551
ToppCell10x5'-Liver-Lymphocytic_B_plasma|Liver / Manually curated celltypes from each tissue

PDIA4 P4HB PDIA5

7.53e-05186203a2c7430781f432c9c90ac4d620f4518ff767a223
ToppCellnormal_Lung-B_lymphocytes-MALT_B_cells|B_lymphocytes / Location, Cell class and cell subclass

PDIA4 P4HB PDIA5

7.53e-05186203f4d72463c5f287da6436287eda0a349b4185841e
ToppCellLAM-Lymphoid-B-cell-2|Lymphoid / Condition, Lineage and Cell class

PDIA4 PDIA5 BRSK1

7.53e-05186203bcfe0bf2f7f745146b74496a4fcfccd869ad7c6f
ToppCellfacs-Skin-Anagen-3m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB GALNT1

7.53e-051862039a7932d0a208f3997216bd21a72913cc82b59fc9
ToppCellILEUM-inflamed-(5)_Plasma|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PDIA4 P4HB BRSK1

7.53e-051862034d105437487bf04f8cd6129b822d5c060af0bee8
ToppCellB_cells-Plasma_cells_and_plasmablasts|World / Immune cells in Kidney/Urine in Lupus Nephritis

PDIA4 PDIA5 BRSK1

7.65e-051872039325cadd5f2c667d526696899e7aa36a98226d4b
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B_plasma-Plasma_cells|lymph-node_spleen / Manually curated celltypes from each tissue

PDIA4 P4HB PDIA5

7.77e-05188203c7b1807c96f87fbcd37739a159cf00f9a1ff5d71
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDIA4 P4HB PDIA5

7.77e-0518820334873972dff9284dfcd26bb698c9d1df007f1cbb
ToppCellILEUM-inflamed-(5)_IgM_plasma_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PDIA4 P4HB BRSK1

7.89e-05189203fa9387d120cde6416998234c6ebd0ef74deed768
ToppCellfacs-Skin-Anagen|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA3

7.89e-05189203adbfc723130079b4caf551f66d2aee86fab1903c
ToppCellILEUM-inflamed-(5)_IgG_plasma_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PDIA4 P4HB BRSK1

8.02e-0519020376baa41b217ae6fd62a58971912e8ecfe1dc03e7
ToppCellfacs-Skin-Anagen-3m-Epithelial|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA3

8.02e-05190203888ded899f0513d41bf655896d59ae8ef74e0978
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PDIA4 P4HB PDIA5

8.02e-0519020376b747bafff09bf8375a5717c9f213cbfb405bac
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-MALT_B_cells|B_lymphocytes / Location, Cell class and cell subclass

PDIA4 P4HB BRSK1

8.02e-05190203ce70336679a2b713836e7497e6dc48aac612b018
ToppCellfacs-Skin-Anagen-3m|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA3

8.02e-051902033466cebab16964e94da130d0673fa32e7d90b5ed
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDIA4 P4HB PDIA5

8.02e-05190203f85cdd79eefd699ada7a91bf4997cc730a9b9846
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDIA4 P4HB PDIA5

8.14e-05191203208cd307826b5af89f8f10c0c915f90f80a25c6c
ToppCellPBMC-Convalescent-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDIA4 P4HB PDIA5

8.14e-05191203dd1d38a531a272a746c16807688013d29cab823a
ToppCellControl-Plasmablast|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PDIA4 P4HB PDIA5

8.14e-051912033df5bbdb29bbcbcb8476fdf126b6d4c1ac67d64b
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-Plasma_cell|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDIA4 P4HB PDIA5

8.14e-05191203fca19f2719806f3dc2dd2add7252ab1198548f4d
ToppCellSmart-seq2-spleen_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PDIA4 P4HB PDIA5

8.14e-051912037b4b5d90d1023d03239ed986f273afa734d3124d
ToppCellnormal_Lymph_Node-B_lymphocytes-Plasma_cells|B_lymphocytes / Location, Cell class and cell subclass

PDIA4 P4HB PDIA5

8.27e-05192203119832d4aee29ddda2485fc3e5dcdaacf833cc30
ToppCellremission-Plasmablast|remission / disease stage, cell group and cell class

PDIA4 P4HB PDIA5

8.27e-051922034bcf22061905177ad8625b87be2fbca9bff03ec6
ToppCellfacs-Skin-Anagen-3m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 P4HB PDIA3

8.27e-05192203ec1fd2fb6e71f87189d66261909a84e2be63cacb
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-Plasma_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDIA4 P4HB PDIA5

8.27e-05192203ec279980602292fc8ed6362edd36a5c772d59777
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 PDIA3 RNF13

8.40e-0519320306b65110db974f4ef90d3511ff34428976a52c9c
ToppCellPBMC-Convalescent-Lymphocyte-B-Plasmablast-Plasmablast-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PDIA4 P4HB PDIA5

8.40e-05193203902dea0bf6c2997d8b877ae01113460e511a364a
ToppCellfacs-Lung-EPCAM-18m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 BTG1 SCUBE2

8.40e-05193203b9ac74357435f2f24aaede62b2a1d31b5d96a12c
ToppCellPBMC-Convalescent-Lymphocyte-B-Plasmablast|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDIA4 P4HB PDIA5

8.40e-05193203239f2ac64f63d4d65997ba83b932a1fab1909efb
ToppCellPBMC-Convalescent-Lymphocyte-B-Plasmablast-Plasmablast|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDIA4 P4HB PDIA5

8.40e-051932032790b245d6052063c207087b91fb9375a0e8055d
ToppCellPBMC-Convalescent-Lymphocyte-B-Plasmablast-Plasmablast|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

PDIA4 P4HB PDIA5

8.40e-0519320394daa8a5d23558998fe3bff585344e22ce679f2d
ToppCellPBMC-Convalescent-Lymphocyte-B-Plasmablast|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

PDIA4 P4HB PDIA5

8.40e-0519320333dad901e0597f0057edc2bfbd64fd81f298b94e
ToppCellwk_15-18|World / Celltypes from embryonic and fetal-stage human lung

CRISPLD2 BTG1 GALNT1

8.40e-05193203a28ff1e80e3e741739abe869df5fbd41352a1ea0
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 PDIA3 RNF13

8.40e-051932039c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-Plasma_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDIA4 P4HB PDIA5

8.40e-051932031f50823bd7ef00500d9d81f0f5c2f6c940c4b1a6
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDIA4 P4HB PDIA5

8.40e-0519320343ffa8ecc72bebcd204279db2bde98ae48d97f90
ToppCellB_cell_maturation-plasma|B_cell_maturation / Lineage and Cell class

PDIA4 P4HB BRSK1

8.40e-051932035415f7e54bc40aec3dbe27fd97f6e9be6db08a48
ToppCellfacs-Brain_Myeloid-Hippocampus-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 PDIA3 RNF13

8.40e-05193203a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PDIA4 P4HB PDIA5

8.40e-0519320322684aa2a368211baba79d29379d0bc442830524
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDIA4 PDIA3 RNF13

8.40e-05193203b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCell10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-GMP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PDIA4 P4HB PDIA3

8.53e-0519420302b7911d07938f04f369a552dedc614930e4396e
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B_plasma|lymph-node_spleen / Manually curated celltypes from each tissue

PDIA4 P4HB PDIA5

8.53e-0519420342f43cac0dec704afd18143192e3ab68360ea076
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-Plasma_cell|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDIA4 P4HB PDIA5

8.53e-05194203297286c57d7ee6338d9cf77b27eb2809378ce15d
ToppCellsevere-Plasmablast|World / disease stage, cell group and cell class

PDIA4 P4HB PDIA5

8.53e-0519420349e8f90db571a89b8a26aef31fcacd66429fed11
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PDIA4 P4HB PDIA5

8.53e-05194203ffba703f61faaac8b4b9a5e46cd335214303de7b
ToppCell(5)_Plasma_IgM|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

PDIA4 P4HB PDIA5

8.53e-0519420347c0f7a1c39ba0836e40ea3ca8066457c0951575
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P4HB PDIA3 BTG1

8.53e-0519420312e42433a7b7c17c46049ef450223daf2976a59a
ToppCellCOVID-19_Convalescent-Lymphoid_P|COVID-19_Convalescent / Disease group, lineage and cell class

PDIA4 P4HB PDIA5

8.66e-051952034fff177aa4617060b594e637885cd0c91e7d6609
ToppCellCOVID-19_Convalescent-Lymphoid_P-Plasmablast|COVID-19_Convalescent / Disease group, lineage and cell class

PDIA4 P4HB PDIA5

8.66e-05195203b4cfc31e4f7e899c6b2578b1ea4fbf609b7ae914
ToppCellsevere-Plasmablast|severe / disease stage, cell group and cell class

PDIA4 P4HB PDIA5

8.66e-05195203e11616ad568e50e4c720b50b0c071f484c31d16b
ToppCellMild/Remission-Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PDIA4 P4HB PDIA5

8.66e-0519520352bdd609253613b7db75dccbc1c01c05e8d73f79
ToppCellfacs-Heart-LA|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 P4HB PDIA3

8.79e-051962038a84aeb1a565dd3e2a690fcaf1ab804f5e253545
ToppCellSevere-Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PDIA4 P4HB PDIA5

8.79e-05196203ee991f1d9936c656f4fbc2e0cec9e0166a34bc5b
ToppCellnormal_Pleural_Fluid-B_lymphocytes-MALT_B_cells|B_lymphocytes / Location, Cell class and cell subclass

PDIA4 P4HB PDIA5

8.79e-051962030ff8cfb209063a8b217df6690ac1dec89004593f
ToppCellCOVID_vent-Lymphocytic-Plasma_cell-IgM_Plasmablast|COVID_vent / Disease condition, Lineage, Cell class and subclass

PDIA4 P4HB PDIA5

8.79e-05196203026a06d8d2089806823e6f6453d3ede84ae93bc6
ToppCell10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-GMP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PDIA4 P4HB PDIA3

8.79e-051962033cf73b33330b9fca5c8abf03f2f0d8244245b522
ToppCell(2)_B_cells-(2)_Plasma_cells|(2)_B_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

PDIA4 P4HB PDIA5

8.79e-05196203cc4f59b885d58e43471e85c51d8e366e68d10846
ToppCellMild/Remission-Plasmablast|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PDIA4 P4HB PDIA5

8.79e-05196203dcf0a804a79a05454658498d1f87320c7e079219
ToppCellCOVID_vent-Lymphocytic-Plasma_cell-IgA_Plasmablast|COVID_vent / Disease condition, Lineage, Cell class and subclass

PDIA4 P4HB PDIA5

8.92e-0519720399fe44ef42c65d24fe64947fd5bf6d91b9a4b2c3
ToppCell10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-GMP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PDIA4 P4HB PDIA3

8.92e-05197203462e91dc51e363d64e1e02d7444a733838e032a5
ToppCellmLN-(2)_B_cell-(20)_B_cell_IgA_Plasma|mLN / shred on region, Cell_type, and subtype

PDIA4 PDIA5 BRSK1

8.92e-05197203a39b384ee9824a08c3b544a9c3c7f0f95f08d6a7
ToppCellSevere|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PDIA4 P4HB PDIA5

8.92e-05197203df3f58b58f82c42c65b0a09c054b669b34502037
ToppCell10x5'v1-week_14-16-Myeloid_monocytic-monocyte-MOP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PDIA4 P4HB PDIA3

8.92e-051972034e68a98bc7e5db7f20e865a0ca21e5a43b3cbb8f
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PDIA4 P4HB PDIA5

8.92e-051972036fe013f98c64b3c5a4e61002254717fb411f8e59
ComputationalOxidoreductases.

PDIA4 P4HB PDIA5 PDIA3

2.44e-0915144MODULE_519
ComputationalOxidoreductases.

PDIA4 P4HB PDIA3

1.51e-03182143MODULE_93
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

PDIA4 PDIA3

1.72e-0348142GAVISH_3CA_MALIGNANT_METAPROGRAM_9_UNFOLDED_PROTEIN_RESPONSE
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

P4HB PDIA3

1.86e-0350142GAVISH_3CA_METAPROGRAM_EPITHELIAL_EPI4
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

PDIA4 PDIA3

1.86e-0350142GAVISH_3CA_MALIGNANT_METAPROGRAM_10_PROTEIN_MATURATION
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

PDIA4 P4HB

1.86e-0350142GAVISH_3CA_METAPROGRAM_B_CELLS_PLASMA
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

PDIA4 PDIA3

1.86e-0350142GAVISH_3CA_METAPROGRAM_MACROPHAGES_UNFOLDED_PROTEIN_RESPONSE
DrugDithiol

PDIA4 P4HB PDIA5 PDIA3

1.61e-06100204CID000010334
Drugtetraarsenic tetrasulfide

PDIA4 P4HB PDIA3

1.92e-0560203ctd:C534735
Drugbetaine

PDIA4 P4HB PDIA5 PDIA3

2.51e-05200204CID000000247
Drugoxidized glutathione

PDIA4 P4HB PDIA5 PDIA3

4.11e-05227204CID000000975
DiseaseSPINOCEREBELLAR ATAXIA 17

P4HB PDIA3

1.41e-059192C1846707
Diseaseimmature platelet fraction

PDIA5 ZMYND8

2.42e-03114192EFO_0009187
Diseaseimmature platelet measurement

PDIA5 ZMYND8

2.64e-03119192EFO_0803541
DiseaseMyocardial Ischemia

P4HB PDLIM5

5.66e-03176192C0151744

Protein segments in the cluster

PeptideGeneStartEntry
HCHCNHEWAPPYCKD

ADAM20

651

O43506
GNWYCNDCKAGKKPH

NSD1

1741

Q96L73
DEPPYCIKAGWKENH

INTS6L

56

Q5JSJ4
AGHPCYLDKPEEWHT

ABHD14B

186

Q96IU4
IHCPAHCKDEPSYWA

CRISPLD2

411

Q9H0B8
PWCGHCKALAPEYAK

P4HB

51

P07237
GKSWHPEEFNCAHCK

PDLIM5

436

Q96HC4
CKYKRIGCPWHGPFH

CYHR1

166

Q6ZMK1
KCHHLKGNQLWEYDP

GALNT1

496

Q10472
KHPWYLGGKHEPDPC

BRSK1

281

Q8TDC3
CDYPCQQAHWPEHMK

ZMYND8

1046

Q9ULU4
ECQCHPGYKLHWNKK

SCUBE2

426

Q9NQ36
FYAPWCPHCKKVIPH

PDIA5

421

Q14554
HQKCPPWWYKCAHKV

SCN4A

541

P35499
FYAPWCGHCKNLEPK

PDIA3

401

P30101
LPCSHAYHCKCVDPW

RNF13

256

O43567
FYAPWCGHCKKLAPE

PDIA4

201

P13667
CHSPWHEGVNCKEYK

RNF217

386

Q8TC41
HYKHHWFPEKPCKGS

BTG1

51

P62324
HTGEKPYECPVCWKA

ZNF182

536

P17025
LGEHDPWYCPNCKKH

USP4

791

Q13107