Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
HumanPhenoAbnormal palm morphology

KRT6B KMT2B DSC2 AIP NHP2 CREBBP JARID2 USF3 PIEZO2 DST BRAF KRT6C TINF2 PEX5 ASXL2 MBD5 NIPBL ZNF292

9.15e-085214418HP:0100871
HumanPhenoAbnormal skin morphology of the palm

KRT6B DSC2 AIP NHP2 CREBBP JARID2 USF3 PIEZO2 DST BRAF KRT6C TINF2 PEX5 ASXL2 NIPBL ZNF292

1.31e-074134416HP:0040211
HumanPhenoRegional abnormality of skin

KRT6B DSC2 AIP NHP2 WNK1 CREBBP SCYL2 JARID2 USF3 PIEZO2 DST BRAF KRT6C TINF2 PEX5 ASXL2 NIPBL ZNF292

1.64e-075414418HP:0011356
HumanPhenoAbnormality of the plantar skin of foot

KRT6B DSC2 AIP NHP2 CREBBP USF3 DST BRAF KRT6C TINF2

1.29e-061714410HP:0100872
HumanPhenoPalmoplantar hyperkeratosis

KRT6B DSC2 NHP2 USF3 DST BRAF KRT6C TINF2

1.12e-05129448HP:0000972
HumanPhenoPalmar hyperkeratosis

KRT6B DSC2 NHP2 USF3 DST BRAF KRT6C TINF2

1.26e-05131448HP:0010765
HumanPhenoPlantar hyperkeratosis

KRT6B DSC2 NHP2 USF3 DST BRAF KRT6C TINF2

1.33e-05132448HP:0007556
HumanPhenoPalmoplantar keratoderma

KRT6B DSC2 NHP2 USF3 BRAF KRT6C TINF2

4.52e-05114447HP:0000982
HumanPhenoEpidermal thickening

KRT6B DSC2 DUSP6 AIP NHP2 JARID2 USF3 DST BRAF KRT6C TINF2 PEX5

5.73e-053794412HP:0011368
HumanPhenoWhite lesion of the oral mucosa

KRT6B NHP2 KRT6C TINF2

8.53e-0528444HP:0025125
HumanPhenoOral leukoplakia

KRT6B NHP2 KRT6C TINF2

8.53e-0528444HP:0002745
HumanPhenoThickened skin

KRT6B DSC2 DUSP6 AIP NHP2 JARID2 USF3 DST BRAF KRT6C TINF2 PEX5

1.99e-044314412HP:0001072
MousePhenoabnormal ventricle myocardium morphology

ERBB2 XBP1 WNK1 ITGAV CREBBP JARID2 XIRP2 NIPBL

2.02e-061161028MP:0010499
MousePhenoabnormal vitelline vasculature morphology

ERBB2 SUPT20H ZNF148 UBR4 SUPT20HL2 AIP WNK1 ITGAV CREBBP BRAF

8.20e-0623510210MP:0003229
MousePhenoabnormal trabecula carnea morphology

ERBB2 XBP1 WNK1 ITGAV JARID2 XIRP2

2.19e-05781026MP:0004067
DomainLRRC37AB_C

LRRC37A3 LRRC37A2 LRRC37A

1.40e-0641333IPR029423
DomainLRRC37AB_C

LRRC37A3 LRRC37A2 LRRC37A

1.40e-0641333PF14914
DomainLRRC37_N

LRRC37A3 LRRC37A2 LRRC37A

1.40e-0641333IPR032754
DomainLRRC37

LRRC37A3 LRRC37A2 LRRC37A

1.40e-0641333PF15779
DomainLRRC37A/B-like

LRRC37A3 LRRC37A2 LRRC37A

1.40e-0641333IPR015753
DomainLRR_8

LRRC37A3 LRRC37A2 LRRC69 CPN2 LGR5 LRRC37A LRRC20 SLITRK5

3.11e-051711338PF13855
DomainLRR_TYP

LRRC37A3 LRRC37A2 LRRC69 CPN2 LGR5 LRRC37A LRRC20 SLITRK5

3.98e-051771338SM00369
DomainLeu-rich_rpt_typical-subtyp

LRRC37A3 LRRC37A2 LRRC69 CPN2 LGR5 LRRC37A LRRC20 SLITRK5

3.98e-051771338IPR003591
DomainSpt20

SUPT20H SUPT20HL2

5.03e-0521332IPR021950
DomainSpt20

SUPT20H SUPT20HL2

5.03e-0521332PF12090
DomainDynein_heavy_chain_D4_dom

DNAH12 DNAH6 DNAH8

1.21e-04141333IPR024317
DomainDynein_heavy_dom-2

DNAH12 DNAH6 DNAH8

1.21e-04141333IPR013602
DomainDHC_N2

DNAH12 DNAH6 DNAH8

1.21e-04141333PF08393
DomainATPase_dyneun-rel_AAA

DNAH12 DNAH6 DNAH8

1.21e-04141333IPR011704
DomainAAA_8

DNAH12 DNAH6 DNAH8

1.21e-04141333PF12780
DomainAAA_5

DNAH12 DNAH6 DNAH8

1.21e-04141333PF07728
DomainTF_octamer

POU2F1 POU2F2

1.50e-0431332IPR000972
DomainDHC_fam

DNAH12 DNAH6 DNAH8

1.51e-04151333IPR026983
DomainDynein_heavy

DNAH12 DNAH6 DNAH8

1.51e-04151333PF03028
DomainDynein_heavy_dom

DNAH12 DNAH6 DNAH8

1.51e-04151333IPR004273
DomainLRR_1

LRRC37A3 LRRC37A2 LRRC69 CPN2 LGR5 LRRC37A LRRC20 SLITRK5

1.76e-042191338PF00560
DomainPOU

POU6F2 POU2F1 POU2F2

1.85e-04161333SM00352
DomainPOU_dom

POU6F2 POU2F1 POU2F2

1.85e-04161333IPR000327
DomainPou

POU6F2 POU2F1 POU2F2

1.85e-04161333PF00157
DomainPOU_1

POU6F2 POU2F1 POU2F2

1.85e-04161333PS00035
DomainPOU_2

POU6F2 POU2F1 POU2F2

1.85e-04161333PS00465
DomainPOU_3

POU6F2 POU2F1 POU2F2

1.85e-04161333PS51179
DomainPOU

POU6F2 POU2F1 POU2F2

2.23e-04171333IPR013847
DomainMeTrfase

METTL2A METTL2B

2.99e-0441332IPR026113
DomainCyt_c1_TM_anchor_C

ERBB2 UGDH

4.96e-0451332IPR021157
DomainL_dom-like

ERBB2 LRRC37A3 LRRC37A2 LRRC69 CPN2 LGR5 LRRC37A LRRC20 SLITRK5

5.76e-043281339IPR032675
DomainLRR

LRRC37A3 LRRC37A2 LRRC69 CPN2 LGR5 LRRC37A SLITRK5

5.97e-042011337PS51450
DomainLeu-rich_rpt

LRRC37A3 LRRC37A2 LRRC69 CPN2 LGR5 LRRC37A LRRC20 SLITRK5

7.28e-042711338IPR001611
DomainNuc_rcpt_coact

NCOA2 CREBBP

7.41e-0461332IPR009110
DomainMethyltransf_12

METTL2A METTL2B

7.41e-0461332IPR013217
DomainMethyltransf_12

METTL2A METTL2B

7.41e-0461332PF08242
DomainZnf_CCCH

CPSF4 ZC3H11A RBM27 MBNL3

7.74e-04581334IPR000571
DomainZF_C3H1

CPSF4 ZC3H11A RBM27 MBNL3

7.74e-04581334PS50103
Domain-

POU6F2 POU2F1 POU2F2

9.11e-042713331.10.260.40
DomainRBD

TIAM2 BRAF

1.03e-0371332SM00455
DomainRBD_dom

TIAM2 BRAF

1.03e-0371332IPR003116
DomainRBD

TIAM2 BRAF

1.03e-0371332PS50898
DomainLambda_DNA-bd_dom

POU6F2 POU2F1 POU2F2

1.13e-03291333IPR010982
Domain-

LRRC37A3 LRRC37A2 LRRC69 CPN2 LGR5 LRRC37A LRRC20 SLITRK5

2.13e-0332113383.80.10.10
PathwayREACTOME_HEME_SIGNALING

NCOA2 CHD9 XPO1 CLOCK CREBBP

1.30e-0549885M41832
PathwayREACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION

NCOA2 CHD9 CLOCK CREBBP

2.23e-0527884M26943
Pubmed

Human transcription factor protein interaction networks.

NCOA2 SUPT20H ZNF148 KMT2B UBR4 PABPC4 MYO18A POU2F1 E2F3 NUP214 TNRC6C ANKHD1 UBN2 RFX1 CREBBP PHF21A RSBN1 CPSF4 DST RBM27 DGKK SEC16A CCAR1 ZFHX3 ASXL2 NIPBL YTHDF2 NPAT RAVER1

2.81e-1314291372935140242
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NCOA2 ZNF148 KMT2B MYCBP2 BAZ2B PABPC4 SRM POU2F1 CHD9 QRICH1 AIP XPO1 UBN2 RFX1 CREBBP PHF21A ZC3H11A RBM27 CCAR1 PLAGL2 ASXL2 NIPBL ZNF292 RAVER1

1.00e-1111031372434189442
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ZNF148 KMT2B MYCBP2 ZGRF1 UBR4 NUP214 ANKHD1 RFX1 PHF21A DST SEC16A ZFHX3 ZMYM5 NPAT

1.31e-094181371434709266
Pubmed

Interaction network of human early embryonic transcription factors.

NCOA2 ZNF148 KMT2B POU2F1 NUP214 UBN2 CREBBP PHF21A DUXB SEC16A ZFHX3 ASXL2 NIPBL

1.57e-093511371338297188
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

NCOA2 ZNF148 XBP1 POU2F1 POU2F2 RFX1 CLOCK PHF21A JARID2 TSC22D1 CPSF4 CIZ1 CCAR1 PLAGL2 ZFHX3 MBNL3 ZMYM5 ZNF292

3.42e-098081371820412781
Pubmed

Functional proteomics mapping of a human signaling pathway.

VWF UBQLN2 KMT2B MYCBP2 UBR4 PABPC4 QRICH1 RFX1 CREBBP ZNF518A SCYL2 DST ASXL2 CCDC181 ZMYM5

1.38e-085911371515231748
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

PRUNE2 UBQLN2 SPATA31E1 UBR4 MAP1LC3A NUP214 WNK1 USF3 XIRP2 STON2 PEX5 MAML2 ZMYM5

1.76e-084301371335044719
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

NCOA2 MAPK8IP1 VWF SUPT20H UBQLN2 MYCBP2 UBR4 CHD9 E2F3 QRICH1 AIP NHP2 CREBBP SCYL2 ARHGAP1 DST CADPS CCAR1 NIPBL ZMYM5 ZNF292

3.45e-0812851372135914814
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PRUNE2 KMT2B CHD9 WNK1 CLOCK ZNF518A SEC16A

1.95e-0710413779205841
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

ZNF148 BAZ2B PABPC4 NUP214 UBN2 RFX1 RSBN1 ZC3H11A SNAP91 TINF2 RBM27 SEC16A CIZ1 CCAR1 NIPBL YTHDF2 NPAT

2.37e-079541371736373674
Pubmed

Clinical value of p53, c-erbB-2, CEA and CA125 regarding relapse, metastasis and death in resectable non-small cell lung cancer.

ERBB2 CEACAM5 MUC16

2.38e-074137314566828
Pubmed

Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.

LRRC37A3 LRRC37A2 LRRC37A

2.38e-074137322419166
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

SUPT20H UBR4 SRM POU2F1 NUP214 QRICH1 XPO1 FCHO2 WNK1 XYLT2 ARHGAP1 ZC3H11A TINF2 LRRC20 SEC16A ASPM MAML2 NIPBL YTHDF2 ZNF292

2.76e-0713271372032694731
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

NCOA2 ZNF148 KMT2B MYCBP2 ANKHD1 UBN2 RFX1 CREBBP SCYL2 ZC3H11A RBM27 SEC16A CIZ1

2.95e-075491371338280479
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ERBB2 SUPT20H ZNF148 DSC2 CHD9 TNFRSF10B ANKHD1 CREBBP PHF21A ZNF518A RSBN1 CADPS SEC16A CIZ1 ASPM TCF25 PEX5 ZFHX3

4.37e-0711161371831753913
Pubmed

A human MAP kinase interactome.

VWF SUPT20H MYO18A NUP214 WNK1 CREBBP TSC22D1 ZNF600 USF3 DST BRAF MBD5

5.56e-074861371220936779
Pubmed

S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component.

POU2F1 POU2F2 NPAT

5.95e-075137312887926
Pubmed

Transcription factor binding sites in the pol gene intragenic regulatory region of HIV-1 are important for virus infectivity.

SPI1 POU2F1 POU2F2

5.95e-075137316061936
Pubmed

A census of human transcription factors: function, expression and evolution.

POU6F2 ZNF148 SPI1 XBP1 POU2F1 POU2F2 E2F3 RFX1 CLOCK TSC22D1 ZC3H11A USF3 FOXD4L3 PLAGL2 ZFHX3 MBNL3

6.37e-079081371619274049
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SUPT20H ZNF148 KMT2B BAZ2B NUP214 UBN2 NHP2 CLOCK PHF21A CPSF4 ZC3H11A DST TINF2 RBM27 CIZ1 CCAR1 ASXL2 NIPBL RAVER1

8.34e-0712941371930804502
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

DUSP6 PABPC4 E2F3 CREBBP ARHGAP1 EYS ZC3H11A DST SEC16A PLAGL2

8.63e-073321371037433992
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

NCOA2 XBP1 POU2F1 POU2F2 FOXD4L6 QRICH1 AIP CREBBP PHF21A CPSF4 FOXD4L3 PLAGL2 ZFHX3 ZNF292

8.89e-077091371422988430
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ZNF148 KMT2B BAZ2B POU2F1 CHD9 E2F3 UBN2 NHP2 RFX1 CIZ1 NIPBL ZNF292 NPAT

9.27e-076081371336089195
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

SUPT20H ZNF148 KMT2B E2F3 PHF21A CPSF4 ZC3H11A RBM27 NPAT RAVER1

1.04e-063391371030415952
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

PABPC4 CREBBP DST TINF2 UGDH SEC16A YTHDF2 RAVER1

1.23e-06197137820811636
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

NCOA2 ZNF148 UBN2 CREBBP PHF21A CPSF4 RBM27 NIPBL RAVER1

1.27e-06268137933640491
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

NCOA2 SUPT20H ZNF148 QRICH1 UBN2 CREBBP PHF21A ZC3H11A SEC16A YTHDF2 ZMYM5

1.63e-064441371134795231
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

BAZ2B UBR4 CHD9 NUP214 RFX1 CLOCK SCYL2 ARHGAP1 SEC16A

1.93e-06282137923667531
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ZNF148 KMT2B MYCBP2 MYO18A POU2F1 NUP214 XPO1 RFX1 ZC3H11A BRAF SEC16A CCAR1 NIPBL RAVER1

2.47e-067741371415302935
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

KRT6B ZNF148 PABPC4 FCHO2 RFX1 SCYL2 ARHGAP1 RSBN1 DST SEC16A ASPM

2.92e-064721371138943005
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PRUNE2 MYCBP2 TNRC6C WNK1 ZNF518A DST CADPS SEC16A

3.31e-06225137812168954
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

NCOA2 ZNF148 UBR4 QRICH1 ANKHD1 DST XIRP2 ZNF292

4.28e-06233137837704626
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

NCOA2 SUPT20H ZNF148 CREBBP PHF21A ZNF518A BRAF SEC16A CIZ1 ZNF292

4.35e-063981371035016035
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

ERBB2 DSC2 PABPC4 NUP214 XPO1 FCHO2 SCYL2 ARHGAP1 DST SEC16A SLITRK5 TCF25 YTHDF2

4.90e-067081371339231216
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

NCOA2 PRUNE2 ERBB2 POU6F2 MYCBP2 CHD9 E2F3 TNRC6C UBN2 CREBBP ARFGEF3 TSC22D1 ZC3H11A USF3 CCAR1 ZFHX3 MBD5 SCGB2B2 RAVER1

6.41e-0614891371928611215
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

GALNT14 ERBB2 CAPN14 CEACAM5 KMT2B DUSP6 WNK1 CREBBP CEACAM1 BRAF DGKK METTL2A METTL2B

6.80e-067301371334857952
Pubmed

Evolutionary dynamism of the primate LRRC37 gene family.

LRRC37A3 LRRC37A2 LRRC37A

7.03e-0610137323064749
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

ERBB2 ZNF148 RBM27 SEC16A SLITRK5 CCAR1 RAVER1

7.73e-06180137735198878
Pubmed

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

LRRC37A2 MYO18A TNRC6C METTL2A METTL2B

1.14e-0574137516625196
Pubmed

Identification of E-box factor TFE3 as a functional partner for the E2F3 transcription factor.

E2F3 WNK1 CREBBP

1.28e-0512137312748276
Pubmed

Proteome-wide characterization of N-glycosylation events by diagonal chromatography.

CEACAM5 CPN2 F10 ITIH1 CEACAM1

1.39e-0577137516944957
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

UBQLN2 MYCBP2 UBR4 PABPC4 SRM NUP214 AIP XPO1 ANKHD1 WNK1 ITGAV ARHGAP1 DST CCAR1 NIPBL YTHDF2 RAVER1

1.46e-0512971371733545068
Pubmed

Precystectomy serum levels of carbohydrate antigen 19-9, carbohydrate antigen 125, and carcinoembryonic antigen: prognostic value in invasive urothelial carcinoma of the bladder.

CEACAM5 MUC16

1.54e-052137224680660
Pubmed

Human Oct-1L isoform has tissue-specific expression pattern similar to Oct-2.

POU2F1 POU2F2

1.54e-052137212663137
Pubmed

Lower serum CA125 level, negative vascular invasion, and wild BRAF were strongly associated with better 2-year disease-free survival in patients with stage III colorectal cancer who received adjuvant chemotherapy.

MUC16 BRAF

1.54e-052137229562502
Pubmed

Bacterial protein domains with a novel Ig-like fold target human CEACAM receptors.

CEACAM5 CEACAM1

1.54e-052137233522633
Pubmed

Protein expression of carcinoembryonic antigen cell adhesion molecules in benign and malignant melanocytic skin lesions.

CEACAM5 CEACAM1

1.54e-052137219461083
Pubmed

Next generation sequencing identified two novel mutations in NIPBL and a frame shift mutation in CREBBP in three Chinese children.

CREBBP NIPBL

1.54e-052137230770747
Pubmed

Functional interaction of Oct transcription factors with the family of repeats in Epstein-Barr virus oriP.

POU2F1 POU2F2

1.54e-052137215831936
Pubmed

Differential dimer activities of the transcription factor Oct-1 by DNA-induced interface swapping.

POU2F1 POU2F2

1.54e-052137211583619
Pubmed

Trajectories of Perioperative Serum Tumor Markers and Colorectal Cancer Outcomes: A Retrospective, Multicenter Longitudinal Cohort Study.

CEACAM5 MUC16

1.54e-052137234801967
Pubmed

Pharmacokinetics of Organic Cation Transporter 1 (OCT1) Substrates in Oct1/2 Knockout Mice and Species Difference in Hepatic OCT1-Mediated Uptake.

POU2F1 POU2F2

1.54e-052137231771949
Pubmed

Interactions between αv-Integrin and HER2 and Their Role in the Invasive Phenotype of Breast Cancer Cells In Vitro and in Rat Brain.

ERBB2 ITGAV

1.54e-052137226222911
Pubmed

Downregulating CREBBP inhibits proliferation and cell cycle progression and induces daunorubicin resistance in leukemia cells.

E2F3 CREBBP

1.54e-052137232945392
Pubmed

Ameloblastoma with mucous cells: A clinicopathological, BRAF mutation, and MAML2 rearrangement study.

BRAF MAML2

1.54e-052137231954088
Pubmed

Paradoxical activation of MEK/ERK signaling induced by B-Raf inhibition enhances DR5 expression and DR5 activation-induced apoptosis in Ras-mutant cancer cells.

TNFRSF10B BRAF

1.54e-052137227222248
Pubmed

Identification of novel single-stranded DNA binding proteins recognizing octamer motif.

POU2F1 POU2F2

1.54e-05213728185580
Pubmed

Expression of CEACAM1 or CEACAM5 in AZ-521 cells restores the type IV secretion deficiency for translocation of CagA by Helicobacter pylori.

CEACAM5 CEACAM1

1.54e-052137230321907
Pubmed

Isolation of scFv antibody fragments against HER2 and CEA tumor antigens from combinatorial antibody libraries derived from cancer patients.

ERBB2 CEACAM5

1.54e-052137223845693
Pubmed

CREB-binding protein regulates lung cancer growth by targeting MAPK and CPSF4 signaling pathway.

CREBBP CPSF4

1.54e-052137226628108
Pubmed

Characterization of large-scale genomic differences in the first complete human genome.

KLRC2 KLRC3

1.54e-052137237403156
Pubmed

3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors increase the binding activity and nuclear level of Oct-1 in mononuclear cells.

POU2F1 POU2F2

1.54e-052137212144930
Pubmed

Several phenylalanine-glycine motives in the nucleoporin Nup214 are essential for binding of the nuclear export receptor CRM1.

NUP214 XPO1

1.54e-052137223264634
Pubmed

Prevalence and Clinicopathological Characteristics of HER2 and BRAF Mutation in Chinese Patients with Lung Adenocarcinoma.

ERBB2 BRAF

1.54e-052137226102513
Pubmed

Nup214 is required for CRM1-dependent nuclear protein export in vivo.

NUP214 XPO1

1.54e-052137216943420
Pubmed

Silencing of E2F3 suppresses tumor growth of Her2+ breast cancer cells by restricting mitosis.

ERBB2 E2F3

1.54e-052137226512919
Pubmed

Specific Binding to Differentially Expressed Human Carcinoembryonic Antigen-Related Cell Adhesion Molecules Determines the Outcome of Neisseria gonorrhoeae Infections along the Female Reproductive Tract.

CEACAM5 CEACAM1

1.54e-052137229760215
Pubmed

Physical and functional interactions between the transcription factor PU.1 and the coactivator CBP.

SPI1 CREBBP

1.54e-052137210050886
Pubmed

TSH signaling overcomes B-RafV600E-induced senescence in papillary thyroid carcinogenesis through regulation of DUSP6.

DUSP6 BRAF

1.54e-052137225499223
Pubmed

Genetic Heterogeneity of HER2 Amplification and Telomere Shortening in Papillary Thyroid Carcinoma.

ERBB2 BRAF

1.54e-052137227775641
Pubmed

Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules.

POU2F1 POU2F2

1.54e-05213728156594
Pubmed

Significance of serum tumor marker levels in peritoneal carcinomatosis of appendiceal origin.

CEACAM5 MUC16

1.54e-052137222941175
Pubmed

Carcinoembryonic antigen (CEA) inhibits NK killing via interaction with CEA-related cell adhesion molecule 1.

CEACAM5 CEACAM1

1.54e-052137215905509
Pubmed

Chromosomal location of the octamer transcription factors, Otf-1, Otf-2, and Otf-3, defines multiple Otf-3-related sequences dispersed in the mouse genome.

CEACAM5 POU2F1 POU2F2 CEACAM1

1.70e-053913741676977
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

PRUNE2 FCHO2 SCYL2 ARHGAP1 DST SNAP91 STON2 SLITRK5

1.85e-05285137834369648
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

NCOA2 ZNF148 POU2F1 NIPBL ZNF292

2.00e-0583137528794006
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH12 DNAH6 DNAH8

2.11e-051413739373155
Pubmed

Gene expression in the developing mouse retina by EST sequencing and microarray analysis.

POU6F2 XBP1 E2F3 ANKHD1 DST ASPM

2.21e-05142137611812828
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

NCOA2 SUPT20H ZGRF1 E2F3 AIP UBN2 WNK1 CREBBP ARFGEF3 SEC16A ASPM

2.28e-055881371138580884
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

KRT6B MYCBP2 UBR4 SRM NUP214 XPO1 ANKHD1 NHP2 CREBBP ZC3H11A DST UGDH SEC16A ASPM CCAR1 NIPBL YTHDF2

2.49e-0513531371729467282
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KMT2B UBR4 CHD9 SNAP91 ZNF292

2.51e-0587137512465718
Pubmed

The sequence of the human genome.

PRUNE2 SPI1 ZGRF1 ERVMER34-1 EYS ZC3H11A USF3 DNAH12 ZFHX3 DNAH6 RAVER1

2.87e-056031371111181995
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

SUPT20H BAZ2B CHD9 UBN2 CREBBP ZNF518A NIPBL

2.99e-05222137737071664
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

UBR4 NUP214 XPO1 ARHGAP1 ZC3H11A DST CADPS UGDH SEC16A RAVER1

3.00e-054981371036634849
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

MYCBP2 PABPC4 MYO18A ANKHD1 UBN2 ARHGAP1 RBM27 UGDH CCAR1 YTHDF2 ZNF292 RAVER1

3.14e-057241371236232890
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

NCOA2 TNRC6C UBN2 CREBBP CIZ1 RAVER1

3.24e-05152137638360978
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NUP214 TNRC6C ARFGEF3 RSBN1 ZC3H11A CADPS SEC16A TCF25 ASXL2

3.61e-05407137912693553
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

NCOA2 ZNF148 UBR4 POU2F1 POU2F2 QRICH1 ANKHD1 NHP2 RFX1 CREBBP PHF21A ZC3H11A ASXL2

3.64e-058571371325609649
Pubmed

Two parallel pathways mediate cytoplasmic localization of the dioxin (aryl hydrocarbon) receptor.

AIP XPO1

4.61e-053137212065584
Pubmed

Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay.

KRT6B KRT6C

4.61e-053137229357356
Pubmed

An updated evaluation of serum sHER2, CA15.3, and CEA levels as biomarkers for the response of patients with metastatic breast cancer to trastuzumab-based therapies.

ERBB2 CEACAM5

4.61e-053137231910438
Pubmed

The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.

POU2F1 POU2F2

4.61e-05313722905684
Pubmed

Clinical evaluation of the simultaneous determination of CA 15-3, CA 125 and sHER2 in breast cancer.

ERBB2 MUC16

4.61e-053137217852076
Pubmed

Leukemia-Associated Nup214 Fusion Proteins Disturb the XPO1-Mediated Nuclear-Cytoplasmic Transport Pathway and Thereby the NF-κB Signaling Pathway.

NUP214 XPO1

4.61e-053137227114368
Pubmed

Serum concentrations of CA 125, CA 15-3, CA 19-9 and CEA in normal pregnancy: a longitudinal study.

CEACAM5 MUC16

4.61e-053137221792548
Pubmed

Alterations of loci encoding PU.1, BOB1, and OCT2 transcription regulators do not correlate with their suppressed expression in Hodgkin lymphoma.

SPI1 POU2F2

4.61e-053137215796964
Pubmed

Positive regulation of the vHNF1 promoter by the orphan receptors COUP-TF1/Ear3 and COUP-TFII/Arp1.

POU2F1 POU2F2

4.61e-05313728622679
Pubmed

Developmental effects of ectopic expression of the glucocorticoid receptor DNA binding domain are alleviated by an amino acid substitution that interferes with homeodomain binding.

POU2F1 POU2F2

4.61e-053137210490647
Pubmed

Triple peptide vaccination as consolidation treatment in women affected by ovarian and breast cancer: Clinical and immunological data of a phase I/II clinical trial.

ERBB2 CEACAM5

4.61e-053137226892612
Pubmed

Recruitment of octamer transcription factors to DNA by glucocorticoid receptor.

POU2F1 POU2F2

4.61e-05313729584182
InteractionFEV interactions

NCOA2 SUPT20H ZNF148 KMT2B POU2F1 UBN2 RFX1 CREBBP PHF21A ZFHX3 ASXL2 NIPBL

9.55e-0920313212int:FEV
InteractionCEBPA interactions

NCOA2 ZNF148 KMT2B SPI1 MYCBP2 BAZ2B PABPC4 SRM POU2F1 CHD9 QRICH1 AIP XPO1 UBN2 RFX1 CREBBP PHF21A ZC3H11A RBM27 CCAR1 PLAGL2 ASXL2 NIPBL ZNF292 RAVER1

4.57e-07124513225int:CEBPA
InteractionKLF8 interactions

NCOA2 SUPT20H ZNF148 KMT2B POU2F1 XPO1 UBN2 CREBBP PHF21A SEC16A NIPBL YTHDF2

1.78e-0632913212int:KLF8
InteractionPHF21A interactions

KMT2B MYCBP2 ZGRF1 UBR4 NUP214 ANKHD1 CLOCK PHF21A DST SEC16A ZFHX3 NPAT

2.74e-0634313212int:PHF21A
InteractionCELF1 interactions

PABPC4 TNRC6C ANKHD1 CPSF4 ZC3H11A RBM27 UGDH CIZ1 CCAR1 YTHDF2 RAVER1

3.14e-0628813211int:CELF1
InteractionNUP43 interactions

KMT2B BAZ2B CHD9 NUP214 UBN2 GRM7 PHF21A ZNF518A RSBN1 DST CIZ1 ZFHX3 ASXL2 NIPBL ZNF292 NPAT

3.40e-0662513216int:NUP43
InteractionSP7 interactions

NCOA2 ZNF148 KMT2B POU2F1 RFX1 CREBBP CPSF4 RBM27 CCAR1 NIPBL RAVER1

5.27e-0630413211int:SP7
InteractionAP2B1 interactions

ERBB2 MAP1LC3A XPO1 TNRC6C FCHO2 WNK1 SCYL2 BRAF SNAP91 STON2 SEC16A PEX5

6.44e-0637313212int:AP2B1
InteractionSOX2 interactions

NCOA2 ZNF148 DSC2 BAZ2B UBR4 PABPC4 POU2F1 CHD9 NUP214 XPO1 ANKHD1 UBN2 NHP2 RFX1 CLOCK ITIH1 SCYL2 ARHGAP1 CPSF4 SEC16A ZFHX3 NIPBL YTHDF2 ZNF292

1.59e-05142213224int:SOX2
InteractionTERF2IP interactions

NCOA2 ZNF148 KMT2B XPO1 RFX1 CREBBP ZC3H11A TINF2 RBM27 CIZ1 CCAR1 NIPBL ZNF292 NPAT

1.61e-0555213214int:TERF2IP
InteractionEGR2 interactions

NCOA2 ZNF148 UBN2 CREBBP PHF21A SEC16A ZFHX3 NIPBL

1.72e-051711328int:EGR2
InteractionCREM interactions

UBQLN2 SPI1 UBR4 POU2F1 XPO1 CREBBP

2.80e-05901326int:CREM
InteractionTLE3 interactions

NCOA2 BAZ2B QRICH1 UBN2 CLOCK CREBBP CCAR1 ZFHX3 ASXL2 NIPBL RAVER1

3.80e-0537613211int:TLE3
InteractionCRX interactions

NCOA2 ZNF148 POU2F1 QRICH1 UBN2 CREBBP ZFHX3 ASXL2 NIPBL

4.59e-052541329int:CRX
InteractionMEX3A interactions

DUSP6 PABPC4 E2F3 CREBBP ARHGAP1 EYS ZC3H11A DST SEC16A PLAGL2 YTHDF2

4.60e-0538413211int:MEX3A
InteractionSPATA1 interactions

UBR4 WNK1 RFX1 SCYL2

4.82e-05311324int:SPATA1
InteractionBAG2 interactions

NCOA2 POU2F1 QRICH1 ANKHD1 UBN2 WNK1 RFX1 CREBBP SCYL2 RBM27 LRRC20 CIZ1 MBNL3 RAVER1

5.91e-0562213214int:BAG2
InteractionFHL2 interactions

POU6F2 E2F3 QRICH1 WNK1 RFX1 CREBBP PHF21A RBM27 CCAR1 ASXL2 RAVER1

6.06e-0539613211int:FHL2
InteractionNRBP2 interactions

UBR4 XPO1 TSC22D1 SEC16A YTHDF2

6.25e-05641325int:NRBP2
InteractionPAN3 interactions

PABPC4 XPO1 TNRC6C CADPS YTHDF2

6.73e-05651325int:PAN3
InteractionCEACAM6 interactions

CEACAM5 UBQLN2 QRICH1 CEACAM1

7.00e-05341324int:CEACAM6
InteractionSNRNP40 interactions

KRT6B KMT2B BAZ2B QRICH1 AIP XPO1 UBN2 PHF21A RSBN1 CIZ1 CCAR1 ZFHX3 NPAT RAVER1

7.62e-0563713214int:SNRNP40
InteractionHNF4A interactions

NCOA2 ZNF148 KMT2B PABPC4 XPO1 UBN2 CREBBP ASXL2 NIPBL

8.46e-052751329int:HNF4A
InteractionRHOQ interactions

DSC2 MYO18A TNFRSF10B FCHO2 LGR5 ITGAV SCYL2 ARFGEF3 ARHGAP1 DST SLITRK5

1.60e-0444213211int:RHOQ
InteractionCNOT2 interactions

XPO1 TNRC6C ANKHD1 SEC16A ZFHX3 YTHDF2 RAVER1

1.74e-041781327int:CNOT2
InteractionKCNA3 interactions

NCOA2 ERBB2 DSC2 PABPC4 MYO18A CHD9 NUP214 XPO1 FCHO2 SCYL2 ARHGAP1 DST SEC16A SLITRK5 TCF25 YTHDF2

1.87e-0487113216int:KCNA3
InteractionDUSP2 interactions

UBR4 DUSP6 AIP ANKHD1 SEC16A

1.92e-04811325int:DUSP2
InteractionFOXJ2 interactions

NCOA2 ZNF148 POU2F2 QRICH1 RFX1

1.92e-04811325int:FOXJ2
InteractionSOX7 interactions

NCOA2 CREBBP PHF21A ZNF518A ZNF292

2.04e-04821325int:SOX7
Cytoband12q22-q23

DUSP6 LGR5

2.65e-053137212q22-q23
CytobandEnsembl 112 genes in cytogenetic band chr2p23

GALNT14 CAPN14 PLB1 UBXN2A ASXL2

8.91e-051491375chr2p23
Cytoband11p11.2

MAPK8IP1 SPI1 PHF21A ARHGAP1

1.16e-0483137411p11.2
GeneFamilyDyneins, axonemal

DNAH12 DNAH6 DNAH8

7.71e-0517903536
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

NCOA2 CLOCK CREBBP

7.71e-0517903486
GeneFamilyPOU class homeoboxes and pseudogenes

POU6F2 POU2F1 POU2F2

1.97e-0423903523
GeneFamilyRho GTPase activating proteins|BCH domain containing

PRUNE2 ARHGAP1

5.06e-0479021299
GeneFamilyZinc fingers CCCH-type

ZC3H11A RBM27 MBNL3

6.96e-043590373
GeneFamilyZinc fingers CXXC-type|Methyl-CpG binding domain containing

BAZ2B MBD5

1.31e-03119021025
GeneFamilyCD molecules|C-type lectin domain family|Killer cell lectin like receptors

KLRC2 KLRC3

1.57e-0312902621
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

NCOA2 SUPT20H ZNF148 MYCBP2 BAZ2B CHD9 E2F3 XPO1 CLOCK CREBBP PHF21A JARID2 RSBN1 DST ZFHX3 NIPBL ZNF292 NPAT

4.91e-0785613618M4500
CoexpressionGSE16385_MONOCYTE_VS_MACROPHAGE_DN

MYCBP2 LRRC69 UBN2 TIAM2 DNAH12 CCAR1 MBD5 NIPBL ZNF292

1.06e-062001369M7901
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

ZNF148 BAZ2B CHD9 E2F3 XPO1 CREBBP JARID2 RSBN1 DST NPAT

3.97e-0630013610M8702
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

ZNF148 MYCBP2 BAZ2B CHD9 E2F3 XPO1 CLOCK CREBBP PHF21A JARID2 DST ZNF292

6.00e-0646613612M13522
CoexpressionGSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DN

MYCBP2 UBN2 CCAR1 MBD5 NIPBL CCDC157 METTL2B ZNF292

1.02e-052001368M7909
CoexpressionDESCARTES_FETAL_STOMACH_SQUAMOUS_EPITHELIAL_CELLS

GALNT14 KRT6B CAPN14 KRT6C CLCA2

2.61e-05671365M40299
CoexpressionGSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN

VWF CHD9 TNRC6C FCHO2 WNK1 TCF25 ASXL2

2.65e-051661367M6826
CoexpressionSCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN

BAZ2B CHD9 QRICH1 ANKHD1 WNK1 CREBBP RBM27 PEX5 PLAGL2 ZFHX3 UPK3A

3.37e-0546713611M1347
CoexpressionGSE37532_WT_VS_PPARG_KO_LN_TREG_UP

POU2F1 POU2F2 TNFRSF10B WNK1 JARID2 CIZ1 PLAGL2

3.85e-051761367M8952
CoexpressionSCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN

BAZ2B CHD9 QRICH1 ANKHD1 WNK1 CREBBP RBM27 PEX5 PLAGL2 ZFHX3 UPK3A

4.66e-0548413611MM999
CoexpressionRODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN

ERBB2 SUPT20H LRRC37A2 CHD9 UBN2 ITGAV RFX1 TIAM2 ZNF518A ARHGAP1 RSBN1 TSC22D1 ZFHX3 ZMYM5

8.13e-0580713614M16651
CoexpressionGSE41867_NAIVE_VS_DAY15_LCMV_EFFECTOR_CD8_TCELL_DN

ZNF148 DUSP6 MYO18A MAP1LC3A UBN2 CREBBP PHF21A

8.63e-052001367M9472
CoexpressionGSE11924_TH2_VS_TH17_CD4_TCELL_DN

BAZ2B CLOCK CREBBP PHF21A ARHGAP1 UGDH NIPBL

8.63e-052001367M3165
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

ZNF148 MYCBP2 UBR4 DUSP6 POU2F2 AIP XPO1 TNRC6C WNK1 CREBBP JARID2 ZC3H11A TINF2 RBM27 ASXL2 NIPBL KLRC2 ZMYM5 ZNF292 NPAT

8.88e-05149213620M40023
ToppCellCOVID-19_Mild-NK_CD56bright|COVID-19_Mild / Disease condition and Cell class

BAZ2B CHD9 B3GNT7 DST ZFHX3 KLRC2 KLRC3

1.33e-06179136790e7a4af195aa2332b07a9f06cde63e72ff49255
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SPI1 BAZ2B DUSP6 MUC16 TCF25 ZFHX3 DNAH8

1.72e-06186136723b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 UBN2 ITGAV ARFGEF3 DST CADPS SEC16A

1.84e-061881367a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF148 DSC2 BAZ2B CHD9 ZNF518A CEACAM1 UBXN2A

2.05e-06191136760c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF148 DSC2 BAZ2B CHD9 ZNF518A CEACAM1 UBXN2A

2.05e-06191136709db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF148 DSC2 BAZ2B CHD9 ZNF518A CEACAM1 UBXN2A

2.05e-061911367973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellmedial-Hematologic-Nonclassical_Monocyte|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLB1 SPI1 PABPC4 POU2F2 NUP214 UPK3A TESC

2.27e-061941367ac203d388a3a3884e316dec0dcbd408e43c6ef6c
ToppCellmedial-2-Hematologic-Nonclassical_Monocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLB1 SPI1 PABPC4 POU2F2 NUP214 UPK3A TESC

2.27e-061941367202e5070728191c46161fa7d931f00be1c7559d4
ToppCellmedial-Hematologic-Nonclassical_Monocyte-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLB1 SPI1 PABPC4 POU2F2 NUP214 UPK3A TESC

2.27e-061941367002cd317732fc6b0d9a72fb46199f71db5a638a7
ToppCellLPS-antiTNF-Endothelial-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZGRF1 GRM7 ERVMER34-1 ZNF600 UPK3A DNAH6

5.40e-06144136675b16adfbe84f69376e6566d531ba7919d5c5192
ToppCelldroplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPI1 POU2F2 ITGAV F10 CEACAM1 PLAGL2

1.22e-0516613661a3a15d1fc76bb91d832cdc6e3da0a6140b94b75
ToppCell3'-Adult-Distal_Rectal-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CEACAM5 DSC2 B3GNT7 CEACAM1 TSC22D1 DST

1.44e-0517113660de81d12a8000f2c59cdb214e67dc526d18098fe
ToppCell3'-Adult-Distal_Rectal-Epithelial-mature_enterocytic-Colonocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CEACAM5 DSC2 B3GNT7 CEACAM1 TSC22D1 DST

1.44e-0517113660597339618fb4d416d55c538eceb353218a55002
ToppCelldroplet-Lung-LUNG-1m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPI1 POU2F2 TIAM2 CEACAM1 XIRP2 PLAGL2

1.64e-051751366c8cfe0ac0c1ac447c626a623cc49692a0b177a1c
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPI1 POU2F2 TIAM2 CEACAM1 XIRP2 PLAGL2

1.64e-05175136661fbd8f685d3daad46449e4c0386a38886496566
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT6B DSC2 KRT6C CLCA2 ASPM AMTN

2.05e-051821366007fa56ed8b91f9af0df2114c00410b2f6cec8b6
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 DUSP6 ANKHD1 CREBBP UBXN2A NIPBL

2.39e-051871366663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCellNon-neuronal-Non-dividing-OPC-OPC|World / Primary Cells by Cluster

DUSP6 B3GNT7 ITGAV UGDH MAML2 KLRC2

2.54e-051891366ddf5be73912570c32c50f4ac2902da9b590526f8
ToppCellNon-neuronal-Non-dividing-OPC|World / Primary Cells by Cluster

DUSP6 B3GNT7 ITGAV UGDH MAML2 KLRC2

2.54e-05189136613848a031ab896b4b24c8319e4745b9b17ff9cfd
ToppCellNon-neuronal-Non-dividing-OPC-OPC-30|World / Primary Cells by Cluster

DUSP6 B3GNT7 ITGAV UGDH MAML2 KLRC2

2.54e-051891366313d165fad541ec6e8dd524b88856e2c93eeb681
ToppCell10x5'-Lung-Myeloid_Monocytic-Classical_monocytes|Lung / Manually curated celltypes from each tissue

PLB1 SPI1 DUSP6 POU2F2 NUP214 TESC

2.61e-051901366a2574f0876ebae3a1d2a39a79cc6cadac8ee1688
ToppCell10x5'-Lung-Myeloid_Monocytic|Lung / Manually curated celltypes from each tissue

SPI1 DUSP6 POU2F2 NUP214 PLAGL2 TESC

2.85e-051931366ebe6be10ef5de9e1da988e263106698d3db42fce
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

ZNF148 POU2F1 CLOCK ARFGEF3 USF3 ASXL2

2.85e-051931366abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SPI1 BAZ2B DUSP6 POU2F2 FCHO2 TCF25

2.85e-0519313661db487e5f81849740d57cc3e2b5739e8f7581efb
ToppCellControl-NK_CD56bright|Control / Disease condition and Cell class

BAZ2B CHD9 B3GNT7 DST ZFHX3 KLRC2

2.85e-0519313668b1e7a226a6057e1097c1525984127b54e823876
ToppCellCOVID-19_Mild-PLT_4|World / Disease Group and Platelet Clusters

EAPP CHD9 DNAH12 XIRP2 ZMYM5 NPAT

2.85e-05193136698a52523aa1efd5d14a2878ed106828a80a33aa2
ToppCellnormal-na-Lymphocytic_NK-NK_bright-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

XBP1 CHD9 B3GNT7 ZNF600 KLRC2 KLRC3

2.94e-051941366dc4aeee379423827e8d291cffe4dbdf2ff6d0bbe
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SPI1 BAZ2B DUSP6 POU2F2 FCHO2 TCF25

2.94e-051941366a94f9f7179a5733e3c378ff8b337e288785433a1
ToppCellnormal-na-Lymphocytic_NK-NK_bright|normal / PBMC cell types (v2) per disease, treatment status, and sex

XBP1 CHD9 B3GNT7 ZNF600 KLRC2 KLRC3

2.94e-0519413668c5f716ce05c1f187de63c1b6948eb9f90ff34fe
ToppCellMyeloid-Myeloid-C_(Cd16+_Monocyte)|Myeloid / shred on cell class and cell subclass (v4)

NCOA2 GALNT14 POU2F2 CEACAM1 SNAP91

2.99e-051171365d1936e76a935216783a73ab414e4147fa48e68eb
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 GALNT14 ITGAV ARFGEF3 DST CADPS

3.02e-051951366bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCellcontrol-Myeloid-CD16_Monocytes|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

DUSP6 PABPC4 POU2F2 HERC2P3 PLAGL2 TESC

3.02e-051951366f398d08a23fdfa6202f73a7aeac3ff4c997fbdfd
ToppCelldroplet-Mammary_Gland-nan-18m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP6 CEACAM1 TSC22D1 PIEZO2 CLCA2 UPK3A

3.11e-05196136600f9171da4c791619e8c4c8c3c7da578c96a30ed
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

B3GNT7 UBN2 CEACAM1 PIEZO2 STON2 ZFHX3

3.11e-051961366b04ca69b0ed44e09c989b575f747e1e819cd8008
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

B3GNT7 UBN2 CEACAM1 PIEZO2 STON2 ZFHX3

3.11e-051961366a31e227de2dc077b81881295b012d22fedbd65ed
ToppCellVE-NK|VE / Condition, Cell_class and T cell subcluster

XBP1 CHD9 ZNF600 ZFHX3 KLRC2 KLRC3

3.20e-051971366cae6ff8763501e7a5897b50188ac2640d65a47c0
ToppCellHealthy/Control-Non-classical_Monocyte|World / Disease group and Cell class

ZMYND15 SPI1 POU2F2 TIAM2 PLAGL2 TESC

3.20e-051971366470784932e1fc3ff69f27cd83f56d85b0c01af63
ToppCellVE-NK-|VE / Condition, Cell_class and T cell subcluster

XBP1 CHD9 ZNF600 ZFHX3 KLRC2 KLRC3

3.20e-051971366ee89b8521fb4faaed9e4d39f7171e45eccf38b00
ToppCelldistal-1-Epithelial-Basal|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KRT6B CEACAM5 EYS KRT6C CLCA2 AMTN

3.20e-05197136625a2ccc98b973611de0d920b1b455d0b40f0d37f
ToppCelldistal-Epithelial-Basal-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KRT6B CEACAM5 EYS KRT6C CLCA2 AMTN

3.20e-05197136675b4292ce2ad7f9c8b6a4781e1cb71f5b18b74e3
ToppCellCOVID-19_Mild-PLT_4|COVID-19_Mild / Disease Group and Platelet Clusters

EAPP CHD9 DNAH12 XIRP2 ZMYM5 NPAT

3.29e-0519813663d8c33dba759df0974aeb2b9a6b5167ae7a18e1f
ToppCellControl-PLT_4|Control / Disease Group and Platelet Clusters

ZNF148 E2F3 DNAH12 XIRP2 ZMYM5 NPAT

3.29e-051981366387fd3037fd52e4d4c42de0588767e58af228b59
ToppCellHealthy_donor-Non-classical_Monocyte|World / disease group, cell group and cell class (v2)

ZMYND15 SPI1 POU2F2 TIAM2 PLAGL2 TESC

3.29e-0519813668a97c8b2a43e6d1e669ce18752841e2006744bd9
ToppCellHealthy_donor-Non-classical_Monocyte|Healthy_donor / disease group, cell group and cell class (v2)

ZMYND15 SPI1 POU2F2 TIAM2 PLAGL2 TESC

3.29e-051981366d4eae333fa100db3ea2d4cbe7a1d6ab14816f0e2
ToppCellHealthy/Control-Non-classical_Monocyte|Healthy/Control / Disease group and Cell class

ZMYND15 SPI1 POU2F2 TIAM2 PLAGL2 TESC

3.29e-0519813660badaf1fa5328d06291c3624d0f63196ffc81527
ToppCellNS-control-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERBB2 MYCBP2 PABPC4 XBP1 CHD9 TSC22D1

3.39e-05199136632bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCellcontrol-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ERBB2 MYCBP2 PABPC4 XBP1 CHD9 TSC22D1

3.39e-0519913663d01f90ffd271ca00129192787e4921bdca7e01e
ToppCellcontrol-Epithelial-Secretory|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ERBB2 MYCBP2 PABPC4 XBP1 CHD9 TSC22D1

3.39e-051991366262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

UBR4 POU2F1 ZNF518A JARID2 EYS

5.93e-0513513653351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCellControl-B_memory-6|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

GALNT14 LRRC20 DGKK TESC DNAH8

6.14e-05136136594f23bef50c0beb54ed39b1a4b340f7aec4e75cd
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-innate_lymphocytic-immature_natural_killer_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

BAZ2B B3GNT7 LGR5 DST SNAP91

8.59e-05146136540fac8a298152ec7f7eeeed5a2d28541aea3b338
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

UBR4 ZNF518A JARID2 MAML2 KLRC3

9.46e-051491365768877bade04ca0321593b8470b5011ad8270431
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ZMYND15 PLB1 SPI1 PIEZO2 XIRP2

1.10e-041541365c6ecc46b99a783373729f7fae0b23216148ffb78
ToppCell10x5'-Liver-Myeloid_Mac-Intestinal_macrophages|Liver / Manually curated celltypes from each tissue

PRUNE2 GALNT14 FCHO2 PIEZO2 DST

1.17e-0415613659a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

GRM7 EYS XIRP2 CADPS DNAH8

1.28e-0415913655335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellfacs-Lung-EPCAM-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPI1 POU2F2 ITGAV TIAM2 CEACAM1

1.40e-041621365484ea4ac40de672dcbd2583a52cb7f385c918814
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPI1 POU2F2 ITGAV TIAM2 CEACAM1

1.40e-041621365bba144ac5332bab9eba2ccf599703c781a7f88f1
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLB1 MYO18A POU2F2 LRRC37A UPK3A

1.40e-0416213650fa93efc9c005d1e649b3f7069ae8641d6e41ed8
ToppCellfacs-Lung-3m-Hematologic-myeloid-non-classical_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPI1 POU2F2 TIAM2 CEACAM1 PLAGL2

1.44e-041631365bbbc3f0ce2616d07136f69ce682ba1d3790711d9
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Cilia-bearing_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

LRRC37A3 TNFRSF10B PLAGL2 DNAH6 METTL2B

1.48e-041641365346e1530b4bf30adbcb2f7d64fdfb4cd8df69d7f
ToppCellfacs-Lung-3m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPI1 POU2F2 TIAM2 CEACAM1 PLAGL2

1.48e-04164136511dfd84f5fb90de330858e1e852848832734e004
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POU6F2 ARFGEF3 DNAH12 CADPS DNAH6

1.53e-0416513654b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCelldroplet-Lung-nan-18m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPI1 POU2F2 TIAM2 CEACAM1 JARID2

1.53e-041651365e32697321cef424c2ad4e11ee9da3e510d5ce505
ToppCellMild-Myeloid-Mast|Mild / Condition, Lineage, Cell class and cell subclass

GALNT14 VWF EYS CADPS TESC

1.53e-0416513655fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCellMild-Myeloid-Mast-|Mild / Condition, Lineage, Cell class and cell subclass

GALNT14 VWF EYS CADPS TESC

1.53e-04165136593d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCelldroplet-Lung-nan-18m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPI1 POU2F2 TIAM2 CEACAM1 JARID2

1.53e-0416513650fbdd043e11aa8dbff4cd3a4da1b2feb49878a09
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

POU2F1 RFX1 USF3 MBD5 IMPG2

1.57e-04166136532d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPI1 POU2F2 TIAM2 CEACAM1 JARID2

1.66e-04168136500cff4698db14e03ca1d1b409e5ed1ad23b12615
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPI1 POU2F2 TIAM2 CEACAM1 PLAGL2

1.66e-0416813654b5be7c6662eceddf90a65015f12908278d1664e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPI1 POU2F2 TIAM2 CEACAM1 PLAGL2

1.66e-041681365689c41f6e9f65381570991cc311cba49a57ec955
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPI1 POU2F2 TIAM2 CEACAM1 JARID2

1.71e-04169136590c00ab30e582b0e2a2be751e1fae9024cfb9ea6
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Rorb-Excitatory_Neuron.Slc17a7-Slc17a6.Rorb-Pcdh20_(Layer_5a)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PLB1 XIRP2 DGKK MBNL3

1.74e-049113641fa597c5fa4523b18fa386ee19237b82778bb1cb
ToppCelldroplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPI1 POU2F2 CEACAM1 JARID2 PLAGL2

1.75e-0417013654d28dc9eb572f43809619f923978cd7494853d43
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPI1 POU2F2 TIAM2 CEACAM1 PLAGL2

1.75e-0417013658e774af244cfe787fa0ea2b6be0c3c2d00bfe4fc
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPI1 POU2F2 TIAM2 CEACAM1 PLAGL2

1.75e-041701365f5140eb9313c0d1bb31f8a761d9c062c56733a61
ToppCelldroplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPI1 POU2F2 CEACAM1 JARID2 PLAGL2

1.80e-041711365ed5886d6aa87b2d73469d39dc217227bd4d4c918
ToppCelldroplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPI1 POU2F2 TIAM2 CEACAM1 PLAGL2

1.80e-04171136500739085fdbc4d64c9faacba2c2adeab580dd2b1
ToppCelldroplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPI1 POU2F2 TIAM2 CEACAM1 PLAGL2

1.85e-0417213655f58ff6cac32546d07b2a49ed250b6c7aa417188
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITIH1 ARFGEF3 EYS DNAH12 CADPS

1.85e-0417213652651dece87c3e3d2d6370f5274ebae357474b825
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-Cilia-bearing_cell|5w / Sample Type, Dataset, Time_group, and Cell type.

KMT2B ITGAV ZNF600 STON2 DNAH6

1.90e-041731365d4cbeae262abfa30d8c5452285d3261a96875610
ToppCellIIH-CD8-naive_CD4|IIH / Condition, Cell_class and T cell subcluster

LRRC37A2 MAP1LC3A TSC22D1 CPSF4 KLRC2

1.90e-0417313654f2843371d18af766c1892529ce286f56c956fde
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSC2 PABPC4 CPN2 F10 ITIH1

2.01e-0417513655c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCell3'-Adult-Distal_Rectal-Epithelial-Tuft-related-Microfold_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DSC2 CEACAM1 DST TESC MAML2

2.01e-0417513658a37b2811f39bb9baa537e8755a29d559eb8185a
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUPT20H CHD9 FCHO2 CLOCK XIRP2

2.06e-041761365749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell(9)_Platelet|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

VWF TSC22D1 DNAH12 XIRP2 STON2

2.11e-0417713650830944c43de300815831a9e2b2fce40965e7d12
ToppCell(9)_Platelet|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

VWF TSC22D1 DNAH12 XIRP2 STON2

2.11e-041771365e63d01c7fce4fa1256212fa7e95f74281edb3a01
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

MYO18A POU2F1 TNRC6C DST SLITRK5

2.11e-041771365e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell3'-Adult-Distal_Rectal-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DSC2 CEACAM1 DST TESC MAML2

2.17e-041781365a95bb77a2c2ce7c38989e6f971812f7ee9f5bd4b
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-4|TCGA-Breast / Sample_Type by Project: Shred V9

KRT6B DSC2 E2F3 B3GNT7 TIAM2

2.17e-04178136544b5ba4e8788d3973749a1717e427647ac4c8579
ToppCelldroplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPI1 POU2F2 F10 CEACAM1 PLAGL2

2.17e-041781365a1f2c134bb7596f678fb4cc11405c374d926ea0f
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MAP1LC3A UBN2 CPSF4 BRAF PEX5

2.17e-0417813658151e5d73407fd9cba382b69a2bc707c81790c7f
ToppCellnucseq-Epithelial-Epithelial_Glandular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KRT6B CEACAM5 MUC16 CEACAM1 CLCA2

2.23e-041791365859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAPK8IP1 GRM7 DNAH12 DNAH6 CCDC157

2.29e-0418013651f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-DC1|lymph-node_spleen / Manually curated celltypes from each tissue

ZMYND15 SPI1 DST STON2 UPK3A

2.29e-041801365a7db1f00566c9acab8b239cbf2e053fb3f2f6a0d
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KRT6B CEACAM5 MUC16 CEACAM1 CLCA2

2.29e-0418013653dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KRT6B CEACAM5 MUC16 CEACAM1 CLCA2

2.29e-041801365668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCellPND07-Epithelial-Epithelial_Airway-Basal-Basal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KRT6B PLB1 DSC2 PHYHIP DST

2.34e-0418113656b43dcaeeb02ad5900772b6f16f1581847050e38
ToppCellPND07-Epithelial-Epithelial_Airway-Basal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KRT6B PLB1 DSC2 PHYHIP DST

2.34e-041811365f50561fdacfb83ba85fe6476e7cbc2bad1ebc826
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 DUSP6 CHD9 FCHO2 NIPBL

2.40e-041821365f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 DUSP6 CHD9 FCHO2 NIPBL

2.59e-0418513657adfa929930cfa795cbfbd9f1a0b439e08aa765d
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A

NCOA2 CHD9 E2F3 CREBBP JARID2 RSBN1 ASPM PLAGL2 NIPBL ZNF292 NPAT

1.14e-08184133112321_DN
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A

NCOA2 CHD9 E2F3 QRICH1 CREBBP PHF21A JARID2 ASPM NIPBL

1.27e-0618213393887_DN
DrugSuccimer

ZMYND15 NCOA2 VWF ZNF148 DSC2 BAZ2B DUSP6 POU2F2 CHD9 ITGAV CREBBP ZNF518A XYLT2 ARFGEF3 TSC22D1 ZC3H11A PIEZO2 BRAF CADPS PLAGL2 MBNL3 ZNF292

4.01e-06126413322ctd:D004113
DrugMagnetite Nanoparticles

ZMYND15 NCOA2 VWF ZNF148 DSC2 BAZ2B DUSP6 POU2F2 CHD9 ITGAV CREBBP ZNF518A XYLT2 ARFGEF3 TSC22D1 ZC3H11A PIEZO2 BRAF CADPS PLAGL2 MBNL3 ZNF292

7.09e-06131013322ctd:D058185
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; PC3; HT_HG-U133A

CHD9 E2F3 CREBBP JARID2 RSBN1 NIPBL ZNF292 NPAT

1.10e-0518013384541_DN
Drugtyrphostin AG-825; Down 200; 25.2uM; MCF7; HT_HG-U133A_EA

NCOA2 ZNF148 CHD9 E2F3 JARID2 RSBN1 NIPBL ZNF292

1.35e-0518513381114_DN
Diseaseimmunoglobulin isotype switching measurement

UBR4 XBP1 ITIH1 KLRC2 KLRC3

1.57e-06441325EFO_0010128
DiseaseMalignant neoplasm of breast

NCOA2 ERBB2 VWF PNLIPRP1 UBR4 LRRC37A2 XBP1 POU2F1 NUP214 NUDT17 WNK1 ZC3H11A LRRC37A BRAF CLCA2 NIPBL

2.56e-05107413216C0006142
DiseaseAdenocarcinoma of lung (disorder)

ERBB2 PABPC4 SRM WNK1 CREBBP SCYL2 BRAF

4.12e-052061327C0152013
Diseaseimmune system disease (implicated_via_orthology)

POU2F1 POU2F2

5.94e-0531322DOID:2914 (implicated_via_orthology)
Diseasecoagulation factor measurement

VWF F10 ASPM

9.44e-05201323EFO_0004634
Diseaseurate measurement, bone density

PLB1 BAZ2B E2F3 QRICH1 TIAM2 SCYL2 EYS SEC16A MAML2 DNAH8 SCGB2B2

1.11e-0461913211EFO_0003923, EFO_0004531
DiseaseCetuximab response

ERBB2 BRAF

1.97e-0451322cv:CN077967
DiseasePanitumumab response

ERBB2 BRAF

1.97e-0451322cv:CN077999
Diseasebrain disease (implicated_via_orthology)

MYCBP2 TIAM2

2.94e-0461322DOID:936 (implicated_via_orthology)
Diseaseacute myeloid leukemia (is_implicated_in)

NCOA2 NUP214 ITGAV CREBBP

5.60e-04841324DOID:9119 (is_implicated_in)
DiseaseDyskeratosis congenita

NHP2 TINF2

7.00e-0491322cv:C0265965
Diseasehypospadias

DGKK ZFHX3 DNAH6

7.11e-04391323EFO_0004209
DiseaseHOYERAAL-HREIDARSSON SYNDROME

NHP2 TINF2

8.73e-04101322C1846142
Diseaseurinary 6‑hydroxymelatonin sulfate to creatinine ratio

GALNT14 ZFHX3

8.73e-04101322EFO_0021488
Diseasevenous thromboembolism, von Willebrand factor measurement

VWF SPI1 FCHO2

8.84e-04421323EFO_0004286, EFO_0004629
Diseasemetabolite measurement, body weight gain

PEX5 ZFHX3

1.27e-03121322EFO_0004566, EFO_0004725
Diseaseacute myeloid leukemia (implicated_via_orthology)

SPI1 CREBBP

1.27e-03121322DOID:9119 (implicated_via_orthology)
DiseaseCarcinogenesis

ERBB2 BRAF

1.50e-03131322C0596263
Diseaseglucose measurement

MAPK8IP1 MYCBP2 LRRC37A3 RFX1 ARHGAP1 LRRC37A SNAP91

1.65e-033801327EFO_0004468
Diseasemonocyte percentage of leukocytes

CHD9 B3GNT7 TNFRSF10B WNK1 DNAH12 RBM27 SEC16A UBXN2A MBD5 KLRC2

1.70e-0373113210EFO_0007989
DiseaseNeoplasm of lung

ERBB2 BRAF

1.74e-03141322cv:C0024121
DiseaseLung cancer

ERBB2 BRAF

1.74e-03141322cv:C0242379
DiseaseLUNG CANCER

ERBB2 BRAF

1.74e-03141322211980
Diseaseresponse to methotrexate

POU6F2 ZNF148

2.29e-03161322GO_0031427
DiseaseDyskeratosis Congenita

NHP2 TINF2

2.29e-03161322C0265965
DiseaseBenign neoplasm of stomach

ERBB2 BRAF

2.58e-03171322C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ERBB2 BRAF

2.58e-03171322C0496905
DiseaseDystonia, Limb

KMT2B CIZ1

2.58e-03171322C0751093
DiseaseDystonia, Diurnal

KMT2B CIZ1

2.58e-03171322C0393610
DiseaseCarcinoma in situ of stomach

ERBB2 BRAF

2.58e-03171322C0154060
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

KMT2B ZNF292

2.58e-03171322DOID:0060307 (is_implicated_in)
Diseasereaction time measurement

EAPP LRRC37A2 TNRC6C PHF21A ARHGAP1 JARID2 SNAP91 CCAR1 ZFHX3

2.89e-036581329EFO_0008393
DiseaseDystonia, Paroxysmal

KMT2B CIZ1

2.90e-03181322C0393588
Diseasefat body mass

PRUNE2 SPATA31E1 MYCBP2 RBM27 CADPS

2.99e-032171325EFO_0005409
DiseaseSystemic Scleroderma

PHF21A XYLT2

3.23e-03191322C0036421
Diseaseage at onset, smoking initiation

NCOA2 MYCBP2

3.23e-03191322EFO_0004847, EFO_0005670
Diseasefactor VIII measurement, Ischemic stroke

VWF FCHO2

3.23e-03191322EFO_0004630, HP_0002140
Diseaselung non-small cell carcinoma (is_implicated_in)

NCOA2 E2F3 XPO1 ZFHX3

3.58e-031391324DOID:3908 (is_implicated_in)
Diseaseprostate adenocarcinoma (is_implicated_in)

NCOA2 BRAF

3.58e-03201322DOID:2526 (is_implicated_in)
DiseaseMalignant Glioma

ERBB2 XBP1 BRAF

3.85e-03701323C0555198
Diseasemixed gliomas

ERBB2 XBP1 BRAF

3.85e-03701323C0259783
DiseaseStomach Carcinoma

ERBB2 BRAF

3.94e-03211322C0699791
Diseasesevere acute respiratory syndrome, COVID-19

NCOA2 GRM7 JARID2 EYS CADPS ZFHX3 MAML2

4.07e-034471327EFO_0000694, MONDO_0100096
Diseasetotal blood protein measurement

NCOA2 SPI1 XPO1 SEC16A MAML2 KLRC2 IMPG2

4.17e-034491327EFO_0004536

Protein segments in the cluster

PeptideGeneStartEntry
ASNTAPLQPEQLQVF

ERBB2

386

P04626
NVTAPTPQQLQAFKN

BRAF

486

P15056
SNNISELPPQVFSQL

CPN2

226

P22792
QPQPQSLLQAQISAA

CCAR1

241

Q8IX12
QPQVLSQQLPFIFQS

BAZ2B

346

Q9UIF8
NNQSLPVSPRLQLSN

CEACAM5

181

P06731
QSLPVSPRLQLSNDN

CEACAM5

361

P06731
LPERISPLQANNQQQ

GJA10

276

Q969M2
QILPNAQLVFSDPSQ

FCHO2

606

Q0JRZ9
SPSSPQQQQQVLNIL

CREBBP

2076

Q92793
SRQQQPVPNSDAVLN

EAPP

166

Q56P03
QLPSFQQNQNVPLLS

AADACL4

231

Q5VUY2
QQQSNQVFPSLSLIP

AMTN

41

Q6UX39
TPAQNNLLQPNFEAA

SNAP91

686

O60641
NLPSSLGQFQQLVQD

CCDC157

246

Q569K6
PFPLFLQQVQSDTAQ

DSC2

151

Q02487
SVNPILSPNQFLKDN

ASPM

386

Q8IZT6
RQNLLSVVPPSQFNF

ASXL2

1076

Q76L83
ADLDALQQNPQPLIF

AIP

136

O00170
ASPQQPQQDFEALLA

CAPN14

21

A8MX76
VANLPPSLTQQQFEE

RAVER1

136

Q8IY67
NEQPTLQSSAQLLLQ

RBM27

676

Q9P2N5
LQSPSPSQLQAAQIQ

QRICH1

156

Q2TAL8
NVAENFSISNPAPQQ

KIAA1107

881

Q9UPP5
NPLFLQQPVISTQQE

LRRC69

231

Q6ZNQ3
LQTPPRSNSVFAVNQ

NPAT

906

Q14207
LTSNLPNVNLPNVNL

CADPS

1011

Q9ULU8
NSPQNLNNPSNEILA

MUC16

4506

Q8WXI7
ALPANAILNQFQPAA

PABPC4

391

Q13310
APQPQLDFQDSQESL

DGKK

1056

Q5KSL6
NQSLLTPLNLQIDPA

KRT6C

141

P48668
SSLQQEAPAQLPQLL

LRRC37A3

236

O60309
LNPQNNISLEFQTFS

EYS

1901

Q5T1H1
SSLQQEAPAQLPQLL

LRRC37A2

236

A6NM11
SSLQQEAPAQLPQLL

LRRC37A

236

A6NMS7
DFQLEVTPQNITLNP

ITIH1

741

P19827
QLQARIQPNPNEVSA

NUDT17

196

P0C025
LFPQVPRSQDTLNNN

MAPK8IP1

166

Q9UQF2
LINSQFPFPQITNNE

DST

2876

Q03001
ASQQFLEQSLQPGLQ

FOXD4L3

46

Q6VB84
SQPLNLALSPQQSAQ

ERVMER34-1

521

Q9H9K5
NQSLLTPLNLQIDPA

KRT6B

141

P04259
NENPNNFQILLLSDP

PNLIPRP1

61

P54315
QNPATQNAPRLLQDS

MYO18A

951

Q92614
FLQDQNAPLVSRAPQ

PEX5

66

P50542
PPQEASNRLQIFQAS

DNAH8

1226

Q96JB1
LFTEFPELAPSQNQN

METTL2B

96

Q6P1Q9
SQQEQTAFLPANQVP

NIPBL

421

Q6KC79
TAFLPANQVPVLQQN

NIPBL

426

Q6KC79
IPPSLNQRVELFQLN

DNAH12

1716

Q6ZR08
PLPQSENKLQTAQQQ

PHF21A

76

Q96BD5
TPNLFQLPQQTQGAL

POU2F2

141

P09086
SLLEEQQSAQLPQAP

NUP214

1516

P35658
PQTQAQLLQPLQALQ

KMT2B

731

Q9UMN6
RNQFQDFPEQLTALP

LRRC20

106

Q8TCA0
VLIQDINDNPPTFSQ

PCDHGB3

121

Q9Y5G1
INDNPPTFSQNITEL

PCDHGB3

126

Q9Y5G1
FLNPQNLSLLTSNPV

POU2F1

676

P14859
LFTEFPELAPSQNQN

METTL2A

96

Q96IZ6
QNNQETPNLKLSPCA

GALNT14

436

Q96FL9
SQQFSQRAVAPPNQL

MAML2

1006

Q8IZL2
PNQLSTQILPNLNQS

MAML2

1051

Q8IZL2
PINNANSTENDPQQL

CCDC181

241

Q5TID7
LNPNTSLNSNNFQIL

CHD9

326

Q3L8U1
NPQEQFSENNALDLP

CEFIP

416

Q711Q0
TQPGLLETFQNNNAL

DNAH6

1156

Q9C0G6
ASPANLLQQTEDQIP

E2F3

401

O00716
NNQSLPVSPRLQLSN

CEACAM1

181

P13688
QIQILPDQTFTALQP

ARFGEF3

2126

Q5TH69
PILNQFTPANISRQA

ITGAV

606

P06756
QPLNLGQFDISNILQ

DUXB

311

A0A1W2PPF3
QQALTNLQLPQPAFI

MBNL3

291

Q9NUK0
PLNQILNQHNAASFP

MBD5

561

Q9P267
LDQINSDPNLLPNVT

GRM7

86

Q14831
QSNNPPLQRSSSLIQ

CPSF4

191

O95639
TENPFDLLDFNQTQP

F10

211

P00742
NPTNLLEFLADRQPQ

B3GNT7

246

Q8NFL0
ILNVTPNLPNLFENA

DUSP6

236

Q16828
ELLVNQNPIAQPLAS

NHP2

26

Q9NX24
SSLPQTVCNQLPNLQ

LGR5

341

O75473
LQAQRKFAQSQPNSP

JARID2

111

Q92833
PPASELNLQQDQKTQ

RSBN1

761

Q5VWQ0
LNSSQPSLRAQVPQF

TNRC6C

1101

Q9HCJ0
QVPQFLSPQVQAQLL

TNRC6C

1111

Q9HCJ0
NFIENPPDLNDSNQA

PRUNE2

401

Q8WUY3
IVLIPFLEQNNFSPN

KLRC2

91

P26717
LQLTNIQVPQQALPT

RFX1

161

P22670
LQVQPITPQLLTNAQ

POU6F2

366

P78424
ASQQFLEQSLQPGLQ

FOXD4L6

46

Q3SYB3
PLPNQQFGVSLQHLQ

ARHGAP1

236

Q07960
PLSIENNLNLNQFNS

SCYL2

576

Q6P3W7
SQAEDTQQALLPSQP

SPATA31E1

666

Q6ZUB1
GNLPLQIQSNEQSFL

MYCBP2

2226

O75592
IVLIPFLEQNNSSPN

KLRC3

91

Q07444
RFPTLTNINENNPTL

MT-ND5

436

P03915
TNINENNPTLLNPIK

MT-ND5

441

P03915
FQIPAQRLFNPSTNL

PHYHIP

206

Q92561
APLQQVQAQLSPLQN

XBP1

171

P17861
PPQSLNLLSQAQLQA

TSC22D1

81

Q15714
NLLSQAQLQAQPLAP

TSC22D1

86

Q15714
PLIATNTNLPLAQQI

TSC22D1

876

Q15714
AENNFTELQSVQPPQ

SPI1

66

P17947
NQLKPLPAVAFNVNN

HERC2P3

971

Q9BVR0
TLQQNFLLGNSSLNP

IMPG2

361

Q9BZV3
VQPFFQNTLTPLNER

PLB1

1321

Q6P1J6
LQLNPTQAFFLLVNQ

MAP1LC3A

71

Q9H492
AQPLLTTLQAQPQDS

PLAGL2

446

Q9UPG8
ATNPFLNETLQDVQP

STON2

311

Q8WXE9
LSTQGQAFPAQQLLN

SUPT20HL2

696

P0C7V6
DNQDTSNLPQLAVPA

ANKHD1

2116

Q8IWZ3
AQLTQPPQQFLQTSR

CLOCK

776

O15516
AINPQVPENQNLISN

CLCA2

46

Q9UQC9
NFNNVPDLELNPIRS

TESC

46

Q96BS2
QLATPNLQQFFPQAT

CIZ1

141

Q9ULV3
DDLQNSQLPQLFPDT

NCOA2

811

Q15596
LPIDQASFASQNRQP

NCOA2

1041

Q15596
LNPINFNPENNVKES

XIRP2

2096

A4UGR9
ANTKPNLNLQVLSNP

UGDH

146

O60701
SLNPGNPVNNQIFLQ

XPO1

961

O14980
QTNPVVKLSNNPQLS

UBN2

951

Q6ZU65
FTPQNNEFQLQLSPK

VWF

2061

P04275
PPNQSQLLEEFLDNF

TIAM2

1001

Q8IVF5
LSNPESLPAQGQAQN

SEC16A

1081

O15027
FDPVPNLQLLFLNNN

SLITRK5

501

O94991
NDQLQLNNVLLTFPP

SAGE2P

176

A6NJ88
ALPTPQAQQLQDVLS

TINF2

161

Q9BSI4
QQNKLSVQSNPSPQL

ZC3H11A

121

O75152
PEQSLPQQRFQLSSA

SUPT20H

711

Q8NEM7
LPNENQTNIPFNELN

PIEZO2

1016

Q9H5I5
NLSAVPLNNLEPITN

UBXN2A

161

P68543
AVNLQQPQQSTFNPE

ZNF292

1431

O60281
LQPQLASVTFATNNP

UPK3A

21

O75631
PQTISLNGQLFALQP

USF3

661

Q68DE3
STNFQEPVQPLTQQQ

SRM

256

P19623
ITQQDLAPQQRAAPQ

TNFRSF10B

56

O14763
QSQQASEFLPPEVNQ

ZNF518A

771

Q6AHZ1
QNFQPTAQQQLTKPA

ZMYM5

226

Q9UJ78
NSNLFSEDAQPQPFI

ZGRF1

701

Q86YA3
PSLNFVTDNQTLPNQ

ZNF148

626

Q9UQR1
LNSPLFTANPQLQEQ

UBQLN2

411

Q9UHD9
NFNISNLQKSISNPP

WNK1

2361

Q9H4A3
NPSPLTEESFLNVQQ

SCGB2B2

51

Q4G0G5
NLQNTLLQQLGVAPF

UBR4

726

Q5T4S7
NNSPNSSLLPQKQEV

ZNF600

141

Q6ZNG1
PQSFPELNIQNKQSL

ZMYND15

496

Q9H091
NDNSNIPNSELLPFL

nan

156

Q499Y3
NAEISQPPALSQLVN

TCF25

486

Q9BQ70
QSFQGLSSILNLPQP

XYLT2

776

Q9H1B5
PAQLSVQQQAAQPTR

YTHDF2

336

Q9Y5A9
QQQAALIQSQLFNPT

ZFHX3

1761

Q15911