Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein-arginine deiminase activity

PADI4 PADI6

4.10e-055412GO:0004668
GeneOntologyMolecularFunctionthyroid hormone binding

THRA THRB

8.58e-057412GO:0070324
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines

PADI4 PADI6

2.24e-0411412GO:0016813
GeneOntologyMolecularFunctionhormone binding

RXFP1 THRA THRB

1.23e-03103413GO:0042562
GeneOntologyMolecularFunctionzinc ion binding

TRIM8 RNF144B NSD1 CDIP1 THRA THRB TRIP4

2.05e-03891417GO:0008270
GeneOntologyBiologicalProcesslung development

MUC19 COL6A1 ASXL1 RXFP1 FBN1 THRA THRB

9.14e-07269417GO:0030324
GeneOntologyBiologicalProcessrespiratory tube development

MUC19 COL6A1 ASXL1 RXFP1 FBN1 THRA THRB

1.01e-06273417GO:0030323
GeneOntologyBiologicalProcessrespiratory system development

MUC19 COL6A1 ASXL1 RXFP1 FBN1 THRA THRB

2.11e-06305417GO:0060541
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

ASXL1 RXFP1 THRA THRB SKP2 TRIP4

8.19e-06244416GO:0009755
GeneOntologyBiologicalProcesspositive regulation of thyroid hormone receptor signaling pathway

THRA THRB

1.16e-053412GO:0002157
GeneOntologyBiologicalProcessfemale courtship behavior

THRA THRB

1.16e-053412GO:0008050
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

ASXL1 THRA THRB SKP2 TRIP4

4.82e-05202415GO:0141193
GeneOntologyBiologicalProcessretinoic acid receptor signaling pathway

ASXL1 THRA THRB

5.86e-0538413GO:0048384
GeneOntologyBiologicalProcesscellular response to hormone stimulus

COL6A1 ASXL1 RXFP1 FBN1 THRA THRB SKP2 TRIP4

7.81e-05727418GO:0032870
GeneOntologyBiologicalProcesslung cell differentiation

COL6A1 THRA THRB

7.93e-0542413GO:0060479
GeneOntologyBiologicalProcesslung epithelial cell differentiation

COL6A1 THRA THRB

7.93e-0542413GO:0060487
GeneOntologyBiologicalProcesscourtship behavior

THRA THRB

8.04e-057412GO:0007619
GeneOntologyBiologicalProcessregulation of thyroid hormone receptor signaling pathway

THRA THRB

1.07e-048412GO:0002155
GeneOntologyBiologicalProcessthyroid hormone receptor signaling pathway

THRA THRB

1.38e-049412GO:0002154
GeneOntologyBiologicalProcessregulation of female receptivity

THRA THRB

1.38e-049412GO:0045924
GeneOntologyBiologicalProcesstype I pneumocyte differentiation

THRA THRB

1.72e-0410412GO:0060509
GeneOntologyBiologicalProcessregulation of lipid storage

ASXL1 PLA2G10 APOC4

2.42e-0461413GO:0010883
GeneOntologyBiologicalProcesslung epithelium development

COL6A1 THRA THRB

2.42e-0461413GO:0060428
GeneOntologyBiologicalProcessfemale mating behavior

THRA THRB

2.51e-0412412GO:0060180
GeneOntologyBiologicalProcesslung alveolus development

COL6A1 ASXL1 FBN1

4.46e-0475413GO:0048286
HumanPhenoImpaired sensitivity to thyroid hormone

THRA THRB

1.05e-052172HP:0002930
HumanPhenoEsotropia

NSD1 COL6A1 WDR45 FBN1 UNC80 HPS3

3.66e-05208176HP:0000565
HumanPhenoSparse, thin scalp hair

NSD1 GJB6

6.27e-054172HP:0002233
HumanPhenoEsodeviation

NSD1 COL6A1 WDR45 FBN1 UNC80 HPS3

7.47e-05236176HP:0020045
HumanPhenoFollicular hyperkeratosis

COL6A1 TRIP4 GJB6

1.19e-0430173HP:0007502
HumanPhenoEnlarged naris

NSD1 UNC80

1.56e-046172HP:0009931
HumanPhenoHeterotropia

NSD1 COL6A1 WDR45 FBN1 UNC80 HPS3

1.97e-04281176HP:0032012
HumanPhenoIncreased arm span

NSD1 FBN1

2.18e-047172HP:0012771
HumanPhenoAbnormal circulating thyroid hormone concentration

FOCAD THRA THRB

2.24e-0437173HP:0031508
MousePhenoincreased activity of thyroid gland

THRA THRB

1.82e-053352MP:0003502
DomainPAD_C

PADI4 PADI6

4.45e-055402IPR013530
DomainProt_Arg_deaminase_cen_dom

PADI4 PADI6

4.45e-055402IPR013733
DomainPAD_N

PADI4 PADI6

4.45e-055402IPR013732
DomainPAD

PADI4 PADI6

4.45e-055402PF03068
DomainPAD_N

PADI4 PADI6

4.45e-055402PF08526
DomainPAD_M

PADI4 PADI6

4.45e-055402PF08527
DomainPAD

PADI4 PADI6

4.45e-055402IPR004303
DomainThyrH_rcpt

THRA THRB

4.45e-055402IPR001728
DomainZnf_RING_CS

TRIM8 RNF144B SCAF11 PDZRN4

4.00e-04163404IPR017907
DomainRING

TRIM8 RNF144B NSD1 SCAF11 PDZRN4

4.63e-04305405SM00184
DomainZnf_RING

TRIM8 RNF144B NSD1 SCAF11 PDZRN4

6.26e-04326405IPR001841
DomainCupredoxin

PADI4 PADI6

1.01e-0322402IPR008972
Domain-

TRIM8 RNF144B NSD1 SCAF11 PDZRN4

2.58e-034494053.30.40.10
DomainZnf_RING/FYVE/PHD

TRIM8 RNF144B NSD1 SCAF11 PDZRN4

2.84e-03459405IPR013083
DomainZF_RING_1

TRIM8 RNF144B SCAF11 PDZRN4

3.39e-03291404PS00518
DomainZF_RING_2

TRIM8 RNF144B SCAF11 PDZRN4

3.69e-03298404PS50089
Domainzf-C4

THRA THRB

4.36e-0346402PF00105
DomainNUCLEAR_REC_DBD_1

THRA THRB

4.36e-0346402PS00031
DomainZnf_hrmn_rcpt

THRA THRB

4.36e-0346402IPR001628
DomainNuclear_hrmn_rcpt

THRA THRB

4.36e-0346402IPR001723
DomainZnF_C4

THRA THRB

4.36e-0346402SM00399
DomainNUCLEAR_REC_DBD_2

THRA THRB

4.36e-0346402PS51030
Domain-

THRA THRB

4.55e-03474021.10.565.10
DomainHOLI

THRA THRB

4.74e-0348402SM00430
DomainNucl_hrmn_rcpt_lig-bd

THRA THRB

4.74e-0348402IPR000536
DomainHormone_recep

THRA THRB

4.74e-0348402PF00104
Domain-

THRA THRB

6.63e-03574023.30.50.10
DomainZnf_NHR/GATA

THRA THRB

6.85e-0358402IPR013088
PathwayKEGG_MEDICUS_REFERENCE_THYROID_HORMONE_SIGNALING_PATHWAY

THRA THRB

1.67e-049312M47629
PathwayBIOCARTA_EGFR_SMRTE_PATHWAY

THRA THRB

2.54e-0411312MM1432
PathwayBIOCARTA_EGFR_SMRTE_PATHWAY

THRA THRB

2.54e-0411312M18837
Pubmed

Strain background effects and genetic modifiers of hearing in mice.

THRA THRB GJB6

3.10e-071144316579977
Pubmed

Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

THRA THRB TRIP4

1.52e-06184437776974
Pubmed

Increased adipogenesis in bone marrow but decreased bone mineral density in mice devoid of thyroid hormone receptors.

THRA THRB

1.56e-06244215780976
Pubmed

Requirement for thyroid hormone receptor beta in T3 regulation of cholesterol metabolism in mice.

THRA THRB

1.56e-06244212145333
Pubmed

Neurodevelopmental control by thyroid hormone receptors.

THRA THRB

1.56e-06244211861164
Pubmed

The two thyroid hormone receptor genes have opposite effects on estrogen-stimulated sex behaviors.

THRA THRB

1.56e-06244210769387
Pubmed

Deafness in TRbeta mutants is caused by malformation of the tectorial membrane.

THRA THRB

1.56e-06244219244534
Pubmed

The ability of thyroid hormone receptors to sense t4 as an agonist depends on receptor isoform and on cellular cofactors.

THRA THRB

1.56e-06244224673558
Pubmed

Functional activation of cerebral metabolism in mice with mutated thyroid hormone nuclear receptors.

THRA THRB

1.56e-06244212933686
Pubmed

Fundamentally distinct roles of thyroid hormone receptor isoforms in a thyrotroph cell line are due to differential DNA binding.

THRA THRB

1.56e-06244222570333
Pubmed

Divergent roles for thyroid hormone receptor beta isoforms in the endocrine axis and auditory system.

THRA THRB

1.56e-06244210430610
Pubmed

TRα protects against atherosclerosis in male mice: identification of a novel anti-inflammatory property for TRα in mice.

THRA THRB

1.56e-06244224797634
Pubmed

Thyroid hormone receptor Thra and Thrb knockout differentially affects osteoblast biology and thyroid hormone responsiveness in vitro.

THRA THRB

1.56e-06244237992217
Pubmed

Role of thyroid hormone receptor subtypes α and β on gene expression in the cerebral cortex and striatum of postnatal mice.

THRA THRB

1.56e-06244223493375
Pubmed

Involvement of T3Ralpha- and beta-receptor subtypes in mediation of T3 functions during postnatal murine intestinal development.

THRA THRB

1.56e-06244210348820
Pubmed

Regulation of neonatal Sertoli cell development by thyroid hormone receptor alpha1.

THRA THRB

1.56e-06244215858214
Pubmed

Thyroid hormone and cardiac function in mice deficient in thyroid hormone receptor-alpha or -beta: an echocardiograph study.

THRA THRB

1.56e-06244212169435
Pubmed

Audiogenic seizure susceptibility in thyroid hormone receptor beta-deficient mice.

THRA THRB

1.56e-06244211496110
Pubmed

Suppression of the deafness and thyroid dysfunction in Thrb-null mice by an independent mutation in the Thra thyroid hormone receptor alpha gene.

THRA THRB

1.56e-06244211726557
Pubmed

Thyroid Hormone Facilitates in vitro Decidualization of Human Endometrial Stromal Cells via Thyroid Hormone Receptors.

THRA THRB

1.56e-06244232242219
Pubmed

Ligand Independent and Subtype-Selective Actions of Thyroid Hormone Receptors in Human Adipose Derived Stem Cells.

THRA THRB

1.56e-06244227732649
Pubmed

The oligomeric state of thyroid receptor regulates hormone binding kinetics.

THRA THRB

1.56e-06244221508093
Pubmed

Polymorphisms in peptidylarginine deiminase associate with rheumatoid arthritis in diverse Asian populations: evidence from MyEIRA study and meta-analysis.

PADI4 PADI6

1.56e-06244223164236
Pubmed

Mice lacking thyroid hormone receptor Beta show enhanced apoptosis and delayed liver commitment for proliferation after partial hepatectomy.

THRA THRB

1.56e-06244220090848
Pubmed

Different functions for the thyroid hormone receptors TRalpha and TRbeta in the control of thyroid hormone production and post-natal development.

THRA THRB

1.56e-0624429927422
Pubmed

Functions of thyroid hormone receptors in mice.

THRA THRB

1.56e-06244210691312
Pubmed

Thyroid hormone receptor-α deletion decreases heart function and exercise performance in apolipoprotein E-deficient mice.

THRA THRB

1.56e-06244226672044
Pubmed

Isolation and characterization of mouse complementary DNAs encoding alpha and beta thyroid hormone receptors from thyrotrope cells: the mouse pituitary-specific beta 2 isoform differs at the amino terminus from the corresponding species from rat pituitary tumor cells.

THRA THRB

1.56e-0624421944303
Pubmed

Mutant thyroid hormone receptors (TRs) isolated from distinct cancer types display distinct target gene specificities: a unique regulatory repertoire associated with two renal clear cell carcinomas.

THRA THRB

1.56e-06244221622534
Pubmed

Thyroid hormone receptors are tumor suppressors in a mouse model of metastatic follicular thyroid carcinoma.

THRA THRB

1.56e-06244220062085
Pubmed

Mice devoid of all known thyroid hormone receptors are viable but exhibit disorders of the pituitary-thyroid axis, growth, and bone maturation.

THRA THRB

1.56e-06244210346821
Pubmed

Hypermetabolism in mice caused by the central action of an unliganded thyroid hormone receptor alpha1.

THRA THRB

1.56e-06244217932484
Pubmed

Thyroid hormone receptor beta-dependent expression of a potassium conductance in inner hair cells at the onset of hearing.

THRA THRB

1.56e-0624429861043
Pubmed

Erythroid defects in TRalpha-/- mice.

THRA THRB

1.56e-06244218203951
Pubmed

Thyroid hormone excess rather than thyrotropin deficiency induces osteoporosis in hyperthyroidism.

THRA THRB

1.56e-06244217327419
Pubmed

Establishment of yeast reporter assay systems to detect ligands of thyroid hormone receptors alpha and beta.

THRA THRB

1.56e-06244219853653
Pubmed

New Insights into the Structure and Function of the Thyroid Hormone Receptor.

THRA THRB

1.56e-06244211725045
Pubmed

Peptidylarginine deiminase (PAD) is a mouse cortical granule protein that plays a role in preimplantation embryonic development.

PADI4 PADI6

1.56e-06244216137333
Pubmed

Thyroid hormone receptor {alpha} modulates lipopolysaccharide-induced changes in peripheral thyroid hormone metabolism.

THRA THRB

1.56e-06244220194731
Pubmed

Genetic features of thyroid hormone receptors.

THRA THRB

1.56e-06244223271024
Pubmed

Thyroid hormone signaling controls hair follicle stem cell function.

THRA THRB

1.56e-06244225657324
Pubmed

Expression of peptides and other neurochemical markers in hypothalamus and olfactory bulb of mice devoid of all known thyroid hormone receptors.

THRA THRB

1.56e-06244211113349
Pubmed

Locomotor deficiencies and aberrant development of subtype-specific GABAergic interneurons caused by an unliganded thyroid hormone receptor alpha1.

THRA THRB

1.56e-06244218287507
Pubmed

Thyroid hormone receptor alpha plays an essential role in the normalisation of adult-onset hypothyroidism-related hypoexpression of synaptic plasticity target genes in striatum.

THRA THRB

1.56e-06244219094093
Pubmed

The two major isoforms of thyroid hormone receptor, TRα1 and TRβ1, preferentially partner with distinct panels of auxiliary proteins.

THRA THRB

1.56e-06244224325866
Pubmed

The thyroid hormone receptors modulate the skin response to retinoids.

THRA THRB

1.56e-06244221858227
Pubmed

Retardation of post-natal development caused by a negatively acting thyroid hormone receptor alpha1.

THRA THRB

1.56e-06244212356724
Pubmed

The T3R alpha gene encoding a thyroid hormone receptor is essential for post-natal development and thyroid hormone production.

THRA THRB

1.56e-0624429250685
Pubmed

Comparative Phenotyping of Mice Reveals Canonical and Noncanonical Physiological Functions of TRα and TRβ.

THRA THRB

1.56e-06244238889231
Pubmed

Increased sensitivity to thyroid hormone in mice with complete deficiency of thyroid hormone receptor alpha.

THRA THRB

1.56e-06244211120878
Pubmed

Thyroid hormone receptor beta-deficient mice show complete loss of the normal cholesterol 7alpha-hydroxylase (CYP7A) response to thyroid hormone but display enhanced resistance to dietary cholesterol.

THRA THRB

1.56e-06244211075809
Pubmed

Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors.

THRA THRB

1.56e-06244211867729
Pubmed

Distinct dysregulation of lipid metabolism by unliganded thyroid hormone receptor isoforms.

THRA THRB

1.56e-06244219131509
Pubmed

Differential expression of thyroid hormone receptor isoforms dictates the dominant negative activity of mutant Beta receptor.

THRA THRB

1.56e-06244212198244
Pubmed

Thyroid hormone receptors are down-regulated in skeletal muscle of patients with non-thyroidal illness syndrome secondary to non-septic shock.

THRA THRB

1.56e-06244220736347
Pubmed

TRs have common and isoform-specific functions in regulation of the cardiac myosin heavy chain genes.

THRA THRB

1.56e-06244211731612
Pubmed

Retardation of cochlear maturation and impaired hair cell function caused by deletion of all known thyroid hormone receptors.

THRA THRB

1.56e-06244211739587
Pubmed

Cardiovascular phenotype and temperature control in mice lacking thyroid hormone receptor-beta or both alpha1 and beta.

THRA THRB

1.56e-06244210362681
Pubmed

Thyroid status during skeletal development determines adult bone structure and mineralization.

THRA THRB

1.56e-06244217488972
Pubmed

Brain glucose utilization in mice with a targeted mutation in the thyroid hormone alpha or beta receptor gene.

THRA THRB

1.56e-06244211481455
Pubmed

Constitutive activation of gene expression by thyroid hormone receptor results from reversal of p53-mediated repression.

THRA THRB

1.56e-0624429372952
Pubmed

Impaired hair growth and wound healing in mice lacking thyroid hormone receptors.

THRA THRB

1.56e-06244225254665
Pubmed

Interference of a mutant thyroid hormone receptor alpha1 with hepatic glucose metabolism.

THRA THRB

1.56e-06244219282388
Pubmed

Gene specific actions of thyroid hormone receptor subtypes.

THRA THRB

1.56e-06244223300972
Pubmed

Thyroid Hormone Receptors Are Differentially Expressed in Granulosa and Cervical Cells of Infertile Women.

THRA THRB

1.56e-06244226715425
Pubmed

Clinical relevance of thyroid dysfunction in human haematopoiesis: biochemical and molecular studies.

THRA THRB

1.56e-06244219903799
Pubmed

[Effects of 2,2',4,4'-tetrabrominated diphenyl ethers on the TRalpha1 and TRbeta1 expression in liver in C57BL/6 mice].

THRA THRB

1.56e-06244220726222
Pubmed

Adipogenesis is differentially impaired by thyroid hormone receptor mutant isoforms.

THRA THRB

1.56e-06244220080985
Pubmed

Isometric force and endurance in skeletal muscle of mice devoid of all known thyroid hormone receptors.

THRA THRB

1.56e-06244212562961
Pubmed

The c-erb-A gene encodes a thyroid hormone receptor.

THRA THRB

1.56e-0624422879243
Pubmed

Life Without Thyroid Hormone Receptor.

THRA THRB

1.56e-06244233558878
Pubmed

Ontogenetic profile of the expression of thyroid hormone receptors in rat and human corpora cavernosa of the penis.

THRA THRB

1.56e-06244220141582
Pubmed

Isoform-specific transcriptional activity of overlapping target genes that respond to thyroid hormone receptors alpha1 and beta1.

THRA THRB

1.56e-06244219628582
Pubmed

Distinct behavioral phenotypes in male mice lacking the thyroid hormone receptor α1 or β isoforms.

THRA THRB

1.56e-06244223567476
Pubmed

Cardiac ion channel expression and contractile function in mice with deletion of thyroid hormone receptor alpha or beta.

THRA THRB

1.56e-06244211159823
Pubmed

Compensatory role of thyroid hormone receptor (TR) alpha 1 in resistance to thyroid hormone: study in mice with a targeted mutation in the TR beta gene and deficient in TR alpha 1.

THRA THRB

1.56e-06244212750454
Pubmed

Cardiac glucose utilization in mice with mutated alpha- and beta-thyroid hormone receptors.

THRA THRB

1.56e-06244215304375
Pubmed

Novel non-genomic signaling of thyroid hormone receptors in thyroid carcinogenesis.

THRA THRB

1.56e-06244219549593
Pubmed

Functionally impaired TR mutants are present in thyroid papillary cancer.

THRA THRB

1.56e-06244211889175
Pubmed

Canonical and Noncanonical Contribution of Thyroid Hormone Receptor Isoforms Alpha and Beta to Cardiac Hypertrophy and Heart Rate in Male Mice.

THRA THRB

1.56e-06244238757582
Pubmed

Distribution of the nuclear thyroid-hormone receptor in extraocular and skeletal muscles.

THRA THRB

1.56e-0624421517709
Pubmed

Naturally Occurring Amino Acids in Helix 10 of the Thyroid Hormone Receptor Mediate Isoform-Specific TH Gene Regulation.

THRA THRB

1.56e-06244228911178
Pubmed

Hormone selectivity in thyroid hormone receptors.

THRA THRB

1.56e-06244211222741
Pubmed

Genetic Variation in PADI6-PADI4 on 1p36.13 Is Associated with Common Forms of Human Generalized Epilepsy.

PADI4 PADI6

1.56e-06244234573423
Pubmed

Gestational di-(2-ethylhexyl) phthalate exposure causes fetal intrauterine growth restriction through disturbing placental thyroid hormone receptor signaling.

THRA THRB

1.56e-06244229753845
Pubmed

Contrasting skeletal phenotypes in mice with an identical mutation targeted to thyroid hormone receptor alpha1 or beta.

THRA THRB

1.56e-06244216051666
Pubmed

Thyroid hormone receptors: lessons from knockout and knock-in mutant mice.

THRA THRB

1.56e-06244212591179
Pubmed

Thyroxine-thyroid hormone receptor interactions.

THRA THRB

1.56e-06244215466465
Pubmed

The thyroid hormone receptors as modulators of skin proliferation and inflammation.

THRA THRB

1.56e-06244221566120
Pubmed

Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.

THRA THRB

1.56e-06244216781732
Pubmed

Thyroid hormone receptor-α and vascular function.

THRA THRB

1.56e-06244222322976
Pubmed

Isometric force and endurance in soleus muscle of thyroid hormone receptor-alpha(1)- or -beta-deficient mice.

THRA THRB

1.56e-06244210712278
Pubmed

Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo.

THRA THRB

1.56e-06244229229863
Pubmed

Identification and consequences of polymorphisms in the thyroid hormone receptor alpha and beta genes.

THRA THRB

1.56e-06244218844476
Pubmed

Gaining ligand selectivity in thyroid hormone receptors via entropy.

THRA THRB

1.56e-06244219926848
Pubmed

Lack of mutations in the thyroid hormone receptor (TR) alpha and beta genes but frequent hypermethylation of the TRbeta gene in differentiated thyroid tumors.

THRA THRB

1.56e-06244217911173
Pubmed

Thyroid Hormone Receptor α Plays an Essential Role in Male Skeletal Muscle Myoblast Proliferation, Differentiation, and Response to Injury.

THRA THRB

1.56e-06244226451739
Pubmed

Effects of thyroid hormone receptor gene disruption on myosin isoform expression in mouse skeletal muscles.

THRA THRB

1.56e-06244210848522
Pubmed

Thyroid hormone regulates tubulin expression in mammalian liver. Effects of deleting thyroid hormone receptor-alpha or -beta.

THRA THRB

1.56e-06244215713690
Pubmed

Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice.

THRA THRB

1.56e-06244212776178
Cytoband12q12

MUC19 SCAF11 PDZRN4

1.29e-054744312q12
CytobandEnsembl 112 genes in cytogenetic band chr12q12

MUC19 SCAF11 PDZRN4

3.13e-0563443chr12q12
Cytoband1p36.13

PADI4 PADI6

1.34e-03564421p36.13
GeneFamilyPeptidyl arginine deiminases

PADI4 PADI6

2.84e-055312677
GeneFamilyRing finger proteins

TRIM8 RNF144B SCAF11 PDZRN4

1.19e-0327531458
GeneFamilyNuclear hormone receptors

THRA THRB

3.18e-034931271
GeneFamilyT cell receptor beta locus at 7q34

TRBV4-1 TRBV12-5

9.72e-0387312372
CoexpressionPEREZ_TP53_TARGETS

TRIM8 RNF144B IPP RASGEF1A COL6A1 CDIP1 GUSBP1 CNKSR1 ZNF654 DSTYK GJB6

2.66e-0612014311M4391
CoexpressionCLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN

COL6A1 FBN1 LPAR1

2.59e-0535433M11788
CoexpressionCLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN

COL6A1 FBN1 LPAR1

2.83e-0536433MM1212
ToppCellLA|World / Chamber and Cluster_Paper

PRUNE2 COL6A1 FBN1 LPAR1 PDZRN4

1.31e-06193445d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PADI4 RXFP1 UNC80 PDZRN4

1.45e-051504444f31867cb85253ff6d22f3b02ef972a42cb41123
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL6A1 RXFP1 KRT34 PDZRN4

2.60e-05174444df5664da3b93c233509781429a9c6d7edf1b8944
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

COL6A1 FBN1 KRT34 LPAR1

2.72e-051764442e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

COL6A1 FBN1 KRT34 LPAR1

2.72e-05176444f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRUNE2 COL6A1 RXFP1 THRB

2.97e-05180444b7513b9816a9cb9f3caaddb2a9fed0be1c7f9805
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRUNE2 COL6A1 RXFP1 THRB

2.97e-05180444f96c5be4705e3d338c0393d2885ac8d5beccd6fd
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-NK-NK-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IPP NSD1 SLA2 PADI4

3.03e-05181444a7f0a83e4f48eca8e753bda13c744cf41359fcc0
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D122|Adult / Lineage, Cell type, age group and donor

COL6A1 FBN1 LPAR1 PDZRN4

3.23e-051844442b7e6f91e11c228f0521e099886867d9e998e78d
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

COL6A1 FBN1 LPAR1 PDZRN4

3.52e-05188444706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGEF1A COL6A1 FBN1 LPAR1

3.59e-05189444544d95df910f1b276995624509a7e41b219baca0
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 FBN1 LPAR1 PDZRN4

3.74e-051914449214655dca96d766737c9f30b624d7fe7050342e
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC19 PRUNE2 PADI4 UNC80

3.74e-05191444d4f77c73311d1149466bbfe4adbd6a301946ec90
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

COL6A1 FBN1 LPAR1 PDZRN4

3.98e-0519444411c79a8c56ece42713b04b321982e41e239f07a5
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

COL6A1 FBN1 LPAR1 PDZRN4

3.98e-05194444014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL6A1 FBN1 LPAR1 PDZRN4

4.06e-05195444ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL6A1 FBN1 LPAR1 PDZRN4

4.39e-05199444993fa050a095017135a6e723c77cd38b9d782e58
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL6A1 FBN1 LPAR1 PDZRN4

4.39e-05199444f835e7ffe976843b0edbf695762d463da85793f3
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A1 FBN1 LPAR1 PDZRN4

4.48e-05200444ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A1 FBN1 LPAR1 PDZRN4

4.48e-05200444389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRUNE2 COL6A1 FBN1 PDZRN4

4.48e-05200444a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A1 FBN1 LPAR1 PDZRN4

4.48e-0520044474e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Neuronal-GABAergic_neurons|GW19 / Sample Type, Dataset, Time_group, and Cell type.

THRB UNC80 PDZRN4

9.04e-05884435582fd7bac60c690ecd1f2aff1d446ccb69f79b9
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Interneuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

THRB UNC80 PDZRN4

2.32e-04121443b2d571f571133c281d72584fe925cebbd2317829
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-NP-L6_NP_ALM_Trh|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL6A1 SLA2 PADI6

4.27e-04149443fe9dff31a30dabd212d53d1295f9f13ff32cb217
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDIP1 THRA TRIP4

4.79e-0415544396c48d835725eac1bc7926f4cddecb67c29b7d7c
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 UNC80 PDZRN4

5.25e-04160443c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PADI4 ZNF792 GJB6

5.25e-04160443bb1bb3673059768c0ea0160d29fff127f3a4ecb4
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PADI4 ZNF792 GJB6

5.25e-0416044376f49b8b4450fa8acd36326bfa36a5d1f4bd95fb
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 UNC80 PDZRN4

5.25e-0416044325c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Lung-EPCAM-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM8 RNF144B DSTYK

5.45e-041624431f1b93394b1f27cbb76b369c19b9313609edd577
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGEF1A FBN1 HPS3

5.45e-0416244356f1789e69a6cb29956e46aba92b290847327c1f
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

COL6A1 FBN1 LPAR1

5.54e-04163443f1ec2625b52664308968b01d8e0275e1e0751480
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col23a1_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL6A1 RXFP1 LPAR1

6.05e-041684433fe432267656aff81b6d92c18d1b6fc0cde73d6a
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL6A1 RXFP1 PDZRN4

6.05e-041684431d58731a481ecac84c15affa84f8041dd67d944c
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Tnaive/CM_CD8|GI_small-bowel / Manually curated celltypes from each tissue

TRIM8 PADI4 SKP2

6.05e-04168443c51244b4bdbfd961e2725306aa9cb25dd66d58bd
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 LPAR1 PDZRN4

6.16e-041694438bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 LPAR1 PDZRN4

6.16e-04169443bb43abad2c049b7f4d307737347290e01b3339a3
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 LPAR1 PDZRN4

6.16e-041694435f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A1 FBN1 LPAR1

6.16e-04169443031465190cd3623a25ef2b868daab8d932c8ff08
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL6A1 RXFP1 PDZRN4

6.26e-0417044349fc45d8a5c3ad89d1649fa46d7a285891379392
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Basal_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

IPP CDIP1 PADI4

6.26e-04170443aabe993c9f337b1caaeb0e64626a3920579c41b7
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Myeloid-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF144B PADI4 THRB

6.26e-04170443f3d5678669dcaed1836014cea543758b7ccc6b46
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL6A1 RXFP1 PDZRN4

6.37e-041714439d5cabd71a901a00eb16c4d151189296f1b3bf6f
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Basal_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

IPP CDIP1 PADI4

6.48e-04172443b66dbfff5e4f53ca8ece91ff9c5dc66a71f07c63
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRUNE2 COL6A1 PDZRN4

6.59e-04173443cb6389536195443633adb06e5f1b7483530773d1
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF144B SMG1 HPS3

6.59e-04173443869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF144B SMG1 HPS3

6.59e-041734430672bd8a4a9d18af343d01f09253fb3388896c10
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

PRUNE2 COL6A1 PDZRN4

6.59e-04173443a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellfacs-Brain_Myeloid-Cerebellum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF144B SMG1 HPS3

6.59e-04173443870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CD24|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL6A1 RXFP1 PDZRN4

6.70e-041744433e29d620b7b4ab1915ddac70ee5a50d09072292b
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL6A1 FBN1 LPAR1

6.70e-041744433c47d069bd836599a8d40eae485c23d4d3487517
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 FBN1 LPAR1

6.70e-0417444368a6ed81e7e1f95b61f7ee20403980fa3a8db4d0
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_11|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PADI4 PADI6 THRB

6.70e-04174443c8cec89369cf3896c5626e447051e76a142cb6df
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_11|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PADI4 PADI6 THRB

6.70e-04174443991f7eab69ea3ee1045a4e44ce60a96db13df6d1
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF144B SMG1 HPS3

6.81e-041754431ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 UNC80 PDZRN4

6.81e-04175443887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL6A1 RXFP1 PDZRN4

6.81e-04175443d4827b4dfad07f11cbdd47fbed287af1afb9b1b8
ToppCellBAL-Control-cDC_11|Control / Compartment, Disease Groups and Clusters

PADI4 PADI6 THRB

6.81e-04175443daf014e15a354956e9149c83fd89d0af0d07eb00
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 FBN1 LPAR1

6.93e-04176443f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN|PND07-28-samps / Age Group, Lineage, Cell class and subclass

COL6A1 FBN1 LPAR1

6.93e-0417644308f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3-5_THEMIS_ELOF1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRUNE2 COL6A1 RXFP1

6.93e-0417644378306517b1e52411a2ba72f141efea4d12c09f25
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 FBN1 LPAR1

6.93e-04176443fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOCAD RXFP1 ZNF792

7.04e-041774431921226196b2ab7919d9f843e60d9f4bd9ec9c57
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

NSD1 SMG1 NBAS

7.04e-0417744382fdd6185b368f54f03de389427cbe3071d21a99
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SMG1 COL6A1 DSTYK

7.16e-04178443c87945146b2734141f07b39d268e0d8086ee0364
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

COL6A1 FBN1 LPAR1

7.27e-04179443dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

PRUNE2 COL6A1 PDZRN4

7.39e-04180443d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL6A1 FBN1 LPAR1

7.39e-041804439adebde5f4ca6dcb90e9113622862e14298465ac
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRUNE2 COL6A1 FBN1

7.51e-04181443b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellRA-01._Fibroblast_I|World / Chamber and Cluster_Paper

FBN1 LPAR1 PDZRN4

7.51e-041814432b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A1 FBN1 LPAR1

7.51e-041814436730e249cac55ae892cc567d9211615882f3dab4
ToppCellP28-Mesenchymal-mesenchymal_fibroblast|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL6A1 FBN1 LPAR1

7.51e-04181443091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL6A1 RXFP1 PDZRN4

7.51e-041814436e8c5460021d3999daec58e3d6661a6fa998fd16
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MUC19 RXFP1 PDZRN4

7.51e-041814439de2f2cc5f02e0ca599c9e0d2cb1e1e4b5aac112
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A1 FBN1 LPAR1

7.51e-041814433462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL6A1 FBN1 LPAR1

7.63e-04182443e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 FBN1 LPAR1

7.63e-04182443dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCellP28-Mesenchymal|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL6A1 FBN1 LPAR1

7.63e-0418244369f9d44694fe4f55a971ae0ac5dc3e7448ee78f3
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSD1 SMG1 SCAF11

7.63e-04182443f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 FBN1 LPAR1

7.63e-04182443c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL6A1 FBN1 LPAR1

7.63e-04182443fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-6_RORB_HPCA|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RXFP1 THRB PDZRN4

7.75e-04183443c7e94fe3e7669db9304b249979fef7a69c30a143
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 FBN1 LPAR1

7.75e-041834435cfcd589a480e67654d3d94e71916f122150db10
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 FBN1 LPAR1

7.75e-04183443c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 FBN1 LPAR1

7.75e-041834437e5c467fd1b156b928f1611a12ab4affb9f714b7
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 FBN1 LPAR1

7.75e-0418344381003ddc24164959dd41bb12fcac72638789b8f2
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A1 FBN1 PDZRN4

7.75e-0418344306a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 FBN1 LPAR1

7.75e-0418344363294d66e3ccf152ffe5d1237106764c14390b62
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL6A1 FBN1 LPAR1

7.88e-0418444301257e5c12e38b849fd3d9496c43ded666249ba5
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 FBN1 LPAR1

7.88e-041844433bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RXFP1 FBN1 LPAR1

7.88e-04184443e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSD1 SMG1 SCAF11

7.88e-041844431154a5ad7b8512272b7476f949ddac350910bfb7
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NBAS COL6A1 CNKSR1

7.88e-0418444342cadfdb5d29a50bd7e901ddd14d42b39e8474f0
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 FBN1 LPAR1

8.00e-041854439954fc85b183c1cc45c3c24e3dadc7984ee6f649
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 FBN1 LPAR1

8.00e-041854433cd0686a14e734a0f243070ab939adcb4c454478
ToppCelldroplet-Kidney-nan-21m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 FBN1 LPAR1

8.00e-0418544333cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 FBN1 LPAR1

8.00e-0418544300258f458cbf6d36449db95528a6b5038d731d2d
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A1 FBN1 LPAR1

8.00e-04185443a94694e226856bc5b168464f52d76004145717a5
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSD1 SMG1 SCAF11

8.00e-041854437adfa929930cfa795cbfbd9f1a0b439e08aa765d
DrugLevothyroxine

THRA THRB

3.32e-062422DB00451
DrugLiothyronine

THRA THRB

3.32e-062422DB00279
DrugLiotrix

THRA THRB

3.32e-062422DB01583
Drug3,5-Dichloro-4-[(4-Hydroxy-3-Isopropylphenoxy)Phenylacetic Acid

THRA THRB

3.32e-062422DB03176
DrugKB 130015

THRA THRB

3.32e-062422ctd:C446946
DrugRafoxanide

THRA THRB

3.32e-062422ctd:D011888
DrugDextrothyroxine

THRA THRB

9.95e-063422DB00509
DrugBithionol

THRA THRB

9.95e-063422ctd:D001735
DrugKB-141

THRA THRB

1.99e-054422CID009863447
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A

NSD1 PRUNE2 ANKRD40 LPAR1 DSTYK

2.81e-051944256171_DN
DrugSulfadiazine [68-35-9]; Up 200; 16uM; PC3; HT_HG-U133A

COL6A1 CDIP1 FBN1 THRB SKP2

2.95e-051964251810_UP
Drug2,3',5,5'-tetrachlorobiphenyl

THRA THRB

3.31e-055422CID000038878
Drug4-hydroxy-2,2',5,5'-tetrachlorobiphenyl

THRA THRB

3.31e-055422CID000039971
DrugdiHPA

THRA THRB

3.31e-055422CID000151819
DrugAzetirelin

APOC4 GJB6

4.96e-056422CID000065841
Drugclosantel

THRA THRB

6.94e-057422ctd:C023342
DrugL-T3-PAL

THRA THRB

6.94e-057422CID005487638
Drugioxynil

THRA THRB

9.24e-058422ctd:C008161
DrugN-bromoacetyl-T3

THRA THRB

1.19e-049422CID000122086
Drug4,4'-hexafluorisopropylidene diphenol

THRA THRB SKP2 KRT34

1.35e-04142424ctd:C583074
Drugpolyglyconate

THRA THRB

1.48e-0410422CID000123833
DrugThiazolidinediones

THRA THRB

1.48e-0410422ctd:D045162
Diseasethyroid hormone resistance syndrome (implicated_via_orthology)

THRA THRB

5.93e-063422DOID:11633 (implicated_via_orthology)
DiseaseGeneralized Thyroid Hormone Resistance

THRA THRB

1.18e-054422C4722330
Diseasecorneal topography

COL6A1 FBN1 LPAR1

5.07e-04109423EFO_0004345
Diseasecortical surface area measurement

TRIM8 FOCAD RASGEF1A SEPSECS FBN1 LPAR1 DSTYK PDZRN4

5.39e-041345428EFO_0010736
Diseasestimulant use measurement

NBAS PDZRN4

7.30e-0428422EFO_0600076
DiseaseHeart Failure, Diastolic

COL6A1 WDR45

1.02e-0333422C1135196
Diseasegranulocyte colony-stimulating factor measurement

SEPSECS APOC4

1.08e-0334422EFO_0008142

Protein segments in the cluster

PeptideGeneStartEntry
GCCLIPCLINDFKDV

CDIP1

176

Q9H305
ELLRVCCCELGVNPD

ANKRD40

291

Q6AI12
LCVLVLACIGACQPE

APOC4

16

P55056
DCIGPSKLCVLCLVV

ASXL1

1526

Q8IXJ9
AVDPALECKLCGQVL

PDZRN4

11

Q6ZMN7
LECKLCGQVLEEPLC

PDZRN4

16

Q6ZMN7
CQNCEKLGELLLCEA

NSD1

1546

Q96L73
KLGELLLCEAQCCGA

NSD1

1551

Q96L73
CCEFLKGQIDPLNCI

IPP

126

Q9Y573
PLITCKLCLCEQSLD

RNF144B

26

Q7Z419
INGRCCLEEKVCSLL

PADI4

606

Q9UM07
CCLEEKICCLLEPLG

PADI6

641

Q6TGC4
NCCAEKICILPNRGL

IL1F10

36

Q8WWZ1
VLLLLDVCCPQCDVL

LPAR1

276

Q92633
KLCELQPEEKCCVVG

POLD2

81

P49005
CVCRDGILLCQIPID

MUC19

1156

Q7Z5P9
CECLRELESCKPGLL

AP5B1

151

Q2VPB7
VLCGPAENKCQELLC

PLA2G10

116

O15496
DQLCLCYDLLECLPE

NBAS

1006

A2RRP1
LPCILILGQDCNVKC

DSTYK

111

Q6XUX3
LEGKVCVCCPSVPLL

FAM189B

131

P81408
CCECKCGPIDLLFVL

COL6A1

606

P12109
CVDINECLLEPRKCA

FBN1

1971

P35555
VLKCGIDPCPNLVDC

GJB6

166

O95452
CGCDPCEQLLLLVSQ

GUSBP1

111

Q15486
CPICLNCLLEKEVGF

SCAF11

41

Q99590
ILQLCCDIVPCLQVK

FOCAD

221

Q5VW36
ICCELEECQNPCLEL

PRUNE2

306

Q8WUY3
DDICCLLKEPCVLQR

SLA2

181

Q9H6Q3
PLCISCCPVKGDLLV

HPS3

136

Q969F9
LLESEDCKLPCNPCA

KRT34

401

O76011
NVDTPELLCKCVKCI

SMG1

286

Q96Q15
GLCDLCPSLEKQLLV

WDR45

146

Q9Y484
CHNILVCCPKELLEQ

CNKSR1

181

Q969H4
CLCLPELLKVSGVCK

SKP2

111

Q13309
ECLLQLGVVPCVEKN

UNC80

681

Q8N2C7
KDILGVCCDPLVLAQ

RASGEF1A

206

Q8N9B8
LCCAVLCLLGAVPID

TRBV4-1

6

A0A577
LPCEDQIILLKGCCM

THRB

296

P10828
LQICVEICGCALQLD

ZNF654

351

Q8IZM8
PVQCLCQGLELDCDE

RXFP1

101

Q9HBX9
TCPCDICGLRLKDIL

ZNF792

131

Q3KQV3
EAKVQELGPDCILCI

SEPSECS

206

Q9HD40
ELPCEDQIILLKGCC

THRA

241

P10827
LCCVVLCLLGEELID

TRBV12-5

6

A0A1B0GX78
CLLGCVDLIDCLSQK

TRIP4

506

Q15650
KNCFEEELICPICLH

TRIM8

6

Q9BZR9