Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncysteine-type deubiquitinase activity

USP36 USP44 USP49 USP17L4 USP17L8

1.16e-06114335GO:0004843
GeneOntologyMolecularFunctiondeubiquitinase activity

USP36 USP44 USP49 USP17L4 USP17L8

1.76e-06124335GO:0101005
GeneOntologyMolecularFunctionubiquitin-like protein peptidase activity

USP36 USP44 USP49 USP17L4 USP17L8

2.87e-06137335GO:0019783
GeneOntologyMolecularFunctioncysteine-type peptidase activity

USP36 USP44 USP49 USP17L4 USP17L8

1.49e-05192335GO:0008234
GeneOntologyMolecularFunctionhistone H2B deubiquitinase activity

USP36 USP49

1.59e-054332GO:0140936
GeneOntologyMolecularFunctionnuclear estrogen receptor activity

ESR1 ESR2

1.59e-054332GO:0030284
GeneOntologyMolecularFunctionhistone deubiquitinase activity

USP36 USP49

7.37e-058332GO:0140934
GeneOntologyMolecularFunctionestrogen response element binding

ESR1 ESR2

1.44e-0411332GO:0034056
GeneOntologyMolecularFunctionpeptidase activity

USP36 USP44 USP49 HGF USP17L4 USP17L8

6.28e-04654336GO:0008233
GeneOntologyMolecularFunctionnuclear steroid receptor activity

ESR1 ESR2

7.76e-0425332GO:0003707
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A2 COL8A1

2.62e-0346332GO:0030020
GeneOntologyMolecularFunctionzinc ion binding

USP44 USP49 ZNF318 TRIM22 ESR1 ESR2

3.06e-03891336GO:0008270
GeneOntologyMolecularFunctionnuclear receptor activity

ESR1 ESR2

4.42e-0360332GO:0004879
GeneOntologyMolecularFunctionligand-activated transcription factor activity

ESR1 ESR2

4.56e-0361332GO:0098531
GeneOntologyBiologicalProcessprotein deubiquitination

USP36 USP44 USP49 USP17L4 USP17L8

1.82e-06125345GO:0016579
GeneOntologyBiologicalProcessprotein modification by small protein removal

USP36 USP44 USP49 USP17L4 USP17L8

3.66e-06144345GO:0070646
GeneOntologyBiologicalProcessSertoli cell proliferation

ESR1 ESR2

7.34e-058342GO:0060011
GeneOntologyBiologicalProcessvagina development

ESR1 ESR2

1.44e-0411342GO:0060068
GeneOntologyCellularComponentbasement membrane collagen trimer

COL4A2 COL8A1

7.58e-058352GO:0098651
GeneOntologyCellularComponentnetwork-forming collagen trimer

COL4A2 COL8A1

7.58e-058352GO:0098642
GeneOntologyCellularComponentcollagen network

COL4A2 COL8A1

7.58e-058352GO:0098645
GeneOntologyCellularComponentcomplex of collagen trimers

COL4A2 COL8A1

5.61e-0421352GO:0098644
DomainUSP_1

USP36 USP44 USP49 USP17L4 USP17L8

1.40e-0770335PS00972
DomainUCH

USP36 USP44 USP49 USP17L4 USP17L8

1.50e-0771335PF00443
DomainUSP_2

USP36 USP44 USP49 USP17L4 USP17L8

1.50e-0771335PS00973
DomainUSP_3

USP36 USP44 USP49 USP17L4 USP17L8

1.61e-0772335PS50235
DomainUSP_dom

USP36 USP44 USP49 USP17L4 USP17L8

1.61e-0772335IPR028889
DomainPeptidase_C19_UCH

USP36 USP44 USP49 USP17L4 USP17L8

1.61e-0772335IPR001394
DomainUSP_CS

USP36 USP44 USP49 USP17L8

5.39e-0666334IPR018200
DomainOest_rcpt/oest-rel_rcp

ESR1 ESR2

3.02e-055332IPR024178
DomainZnF_UBP

USP44 USP49

1.65e-0411332SM00290
Domainzf-UBP

USP44 USP49

2.72e-0414332PF02148
DomainZF_UBP

USP44 USP49

2.72e-0414332PS50271
DomainZnf_UBP

USP44 USP49

2.72e-0414332IPR001607
DomainEGF_3

ATRN C8A VWCE HYAL2

7.51e-04235334PS50026
DomainEGF-like_dom

ATRN C8A VWCE HYAL2

9.31e-04249334IPR000742
DomainEGF_1

ATRN C8A VWCE HYAL2

1.02e-03255334PS00022
DomainEGF-like_CS

ATRN C8A VWCE HYAL2

1.11e-03261334IPR013032
DomainEGF_2

ATRN C8A VWCE HYAL2

1.17e-03265334PS01186
DomainGrowth_fac_rcpt_

ATRN C8A VWCE

2.59e-03156333IPR009030
Domainzf-C4

ESR1 ESR2

2.98e-0346332PF00105
DomainNUCLEAR_REC_DBD_1

ESR1 ESR2

2.98e-0346332PS00031
DomainZnf_hrmn_rcpt

ESR1 ESR2

2.98e-0346332IPR001628
DomainNuclear_hrmn_rcpt

ESR1 ESR2

2.98e-0346332IPR001723
DomainZnF_C4

ESR1 ESR2

2.98e-0346332SM00399
DomainNUCLEAR_REC_DBD_2

ESR1 ESR2

2.98e-0346332PS51030
Domain-

ESR1 ESR2

3.11e-03473321.10.565.10
DomainHOLI

ESR1 ESR2

3.25e-0348332SM00430
DomainNucl_hrmn_rcpt_lig-bd

ESR1 ESR2

3.25e-0348332IPR000536
DomainHormone_recep

ESR1 ESR2

3.25e-0348332PF00104
Domain-

ESR1 ESR2

4.55e-03573323.30.50.10
DomainZnf_NHR/GATA

ESR1 ESR2

4.70e-0358332IPR013088
DomainButyrophylin

ERMAP TRIM22

6.78e-0370332IPR003879
DomainEGF

ATRN VWCE HYAL2

8.12e-03235333SM00181
DomainCollagen

COL4A2 COL8A1

9.86e-0385332PF01391
DomainCollagen

COL4A2 COL8A1

9.86e-0385332IPR008160
DomainSPRY

ERMAP TRIM22

1.03e-0287332SM00449
DomainSPRY

ERMAP TRIM22

1.20e-0294332PF00622
DomainSPRY_dom

ERMAP TRIM22

1.20e-0294332IPR003877
DomainB30.2/SPRY

ERMAP TRIM22

1.22e-0295332IPR001870
DomainB302_SPRY

ERMAP TRIM22

1.22e-0295332PS50188
PathwayKEGG_MEDICUS_ENV_FACTOR_E2_TO_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY

ESR1 ESR2

7.38e-057272M47805
PathwayKEGG_MEDICUS_REFERENCE_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY

ESR1 ESR2

1.92e-0411272M47503
PathwayREACTOME_DEUBIQUITINATION

USP44 USP49 USP17L4 ESR1 USP17L8

2.28e-04299275M27574
PathwayKEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01350

ESR1 ESR2

2.30e-0412272M47798
PathwayWP_SULFATASE_AND_AROMATASE_PATHWAY

ESR1 ESR2

3.17e-0414272M48085
PathwayKEGG_MEDICUS_ENV_FACTOR_E2_TO_RAS_ERK_SIGNALING_PATHWAY

ESR1 ESR2

4.17e-0416272M47801
PathwayREACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER

HGF ESR1 ESR2

5.20e-0483273M27163
PathwayREACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

USP44 USP49 USP17L4 USP17L8

7.77e-04221274M27578
PathwayREACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS

COL4A2 IGHV4-34 IGHV1-2

8.44e-0498273M27152
PathwayKEGG_MEDICUS_REFERENCE_E2_ER_RAS_ERK_SIGNALING_PATHWAY

ESR1 ESR2

8.72e-0423272M47799
PathwayREACTOME_PI3K_AKT_SIGNALING_IN_CANCER

HGF ESR1 ESR2

1.18e-03110273M27162
PathwayREACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK

HGF ESR1 ESR2

1.27e-03113273MM14783
PathwayREACTOME_COMPLEMENT_CASCADE

C8A IGHV4-34 IGHV1-2

1.34e-03115273M19752
PathwayREACTOME_PARASITE_INFECTION

MYO10 IGHV4-34 IGHV1-2

1.37e-03116273M29843
PathwayREACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK

HGF ESR1 ESR2

1.44e-03118273M713
PathwayREACTOME_DEUBIQUITINATION

USP44 USP17L4 ESR1 USP17L8

1.46e-03262274MM15286
PathwayWP_MAMMARY_GLAND_DEVELOPMENT_PREGNANCY_AND_LACTATION_STAGE_3_OF_4

ESR1 ESR2

1.80e-0333272M39455
PathwayWP_NUCLEAR_RECEPTORS

ESR1 ESR2

2.38e-0338272M39657
PathwayWP_NUCLEAR_RECEPTORS

ESR1 ESR2

2.38e-0338272MM15865
PathwayWP_CANCER_PATHWAYS

COL4A2 IFNGR2 HGF ESR1 ESR2

2.47e-03507275M48302
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

MYO10 IGHV4-34 IGHV1-2

2.50e-03143273M27107
PathwayWP_MALE_INFERTILITY

CRISP2 ESR1 ESR2

2.60e-03145273M39856
PathwayPID_ER_NONGENOMIC_PATHWAY

ESR1 ESR2

2.63e-0340272M41
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A2 COL8A1

2.77e-0341272MM15538
PathwayREACTOME_POTENTIAL_THERAPEUTICS_FOR_SARS

IFNGR2 IGHV4-34 IGHV1-2

3.09e-03154273M39007
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A2 COL8A1

3.18e-0344272M27812
PathwayREACTOME_RAS_PROCESSING

USP17L4 USP17L8

3.32e-0345272MM15671
PathwayPID_SYNDECAN_1_PATHWAY

HGF COL8A1

3.47e-0346272M198
Pubmed

Estrogen receptor genotypes and haplotypes associated with breast cancer risk.

ESR1 ESR2

9.84e-07235215604249
Pubmed

Reduced expression of oestrogen receptor-β is associated with tumour invasion and metastasis in oestrogen receptor-α-negative human papillary thyroid carcinoma.

ESR1 ESR2

9.84e-07235229655286
Pubmed

Role of estrogen receptors in neuroprotection by estradiol against MPTP toxicity.

ESR1 ESR2

9.84e-07235217420033
Pubmed

CpG methylation of the ERalpha and ERbeta genes in breast cancer.

ESR1 ESR2

9.84e-07235215254780
Pubmed

Chronic estradiol treatment reduces platelet responses and protects mice from thromboembolism through the hematopoietic estrogen receptor α.

ESR1 ESR2

9.84e-07235222776819
Pubmed

Estrogen/estrogen receptor alpha signaling in mouse posterofrontal cranial suture fusion.

ESR1 ESR2

9.84e-07235219771170
Pubmed

Associations of ESR1 and ESR2 gene polymorphisms with metabolic syndrome and its components in postmenopausal women.

ESR1 ESR2

9.84e-07235230049354
Pubmed

Estradiol down-regulates RF-amide-related peptide (RFRP) expression in the mouse hypothalamus.

ESR1 ESR2

9.84e-07235221325049
Pubmed

Alleles and haplotypes of the estrogen receptor alpha gene are associated with an increased risk of spontaneous abortion.

ESR1 ESR2

9.84e-07235219200973
Pubmed

Expression of estrogen receptor α and β in esophageal squamous cell carcinoma.

ESR1 ESR2

9.84e-07235224101172
Pubmed

Estrogen receptor alpha and beta polymorphisms are associated with semen quality.

ESR1 ESR2

9.84e-07235219959825
Pubmed

Role of estrogen receptor α and β in preserving hippocampal function during aging.

ESR1 ESR2

9.84e-07235223392694
Pubmed

Contribution of estrogen to the pregnancy-induced increase in cardiac automaticity.

ESR1 ESR2

9.84e-07235232798536
Pubmed

Genetic polymorphisms of ESR1 and ESR2 that may influence estrogen activity and the risk of hypospadias.

ESR1 ESR2

9.84e-07235218375409
Pubmed

Epithelial turnover in duodenal familial adenomatous polyposis: A possible role for estrogen receptors?

ESR1 ESR2

9.84e-07235227003997
Pubmed

Effects of ERβ and ERα on OVX-induced changes in adiposity and insulin resistance.

ESR1 ESR2

9.84e-07235232053493
Pubmed

A precisely substituted benzopyran targets androgen refractory prostate cancer cells through selective modulation of estrogen receptors.

ESR1 ESR2

9.84e-07235225655200
Pubmed

Selective oestrogen receptor antagonists inhibit oesophageal cancer cell proliferation in vitro.

ESR1 ESR2

9.84e-07235229390981
Pubmed

Rapid action of 17beta-estradiol on kainate-induced currents in hippocampal neurons lacking intracellular estrogen receptors.

ESR1 ESR2

9.84e-0723529927291
Pubmed

A Systematic Study of the Impact of Estrogens and Selective Estrogen Receptor Modulators on Prostate Cancer Cell Proliferation.

ESR1 ESR2

9.84e-07235232132580
Pubmed

Different expression of estrogen receptors alpha and beta in human myometrium and leiomyoma during the proliferative phase of the menstrual cycle and after GnRHa treatment.

ESR1 ESR2

9.84e-07235211826769
Pubmed

Intermolecular interactions identify ligand-selective activity of estrogen receptor alpha/beta dimers.

ESR1 ESR2

9.84e-07235219022902
Pubmed

Estrogen promotes early osteoblast differentiation and inhibits adipocyte differentiation in mouse bone marrow stromal cell lines that express estrogen receptor (ER) alpha or beta.

ESR1 ESR2

9.84e-07235212021200
Pubmed

Association of Polymorphisms in Estrogen Receptor Genes (ESR1 and ESR2) with Osteoporosis and Fracture-Involvement of Comorbidities and Epistasis.

ESR1 ESR2

9.84e-07235235285722
Pubmed

Diagnostic value of estrogen receptors in thyroid lesions.

ESR1 ESR2

9.84e-07235220581768
Pubmed

Ablation of estrogen receptor alpha or beta eliminates sex differences in mechanical pain threshold in normal and inflamed mice.

ESR1 ESR2

9.84e-07235219285805
Pubmed

Energy Balance Modulation Impacts Epigenetic Reprogramming, ERα and ERβ Expression, and Mammary Tumor Development in MMTV-neu Transgenic Mice.

ESR1 ESR2

9.84e-07235228373182
Pubmed

Expression of estrogen receptors in the pelvic floor of pre- and post-menopausal women presenting pelvic organ prolapse.

ESR1 ESR2

9.84e-07235222038234
Pubmed

Differential association of juvenile and adult systemic lupus erythematosus with genetic variants of oestrogen receptors alpha and beta.

ESR1 ESR2

9.84e-07235220961965
Pubmed

Polymorphisms in the estrogen receptor beta gene but not estrogen receptor alpha gene affect the risk of developing endometriosis in a Japanese population.

ESR1 ESR2

9.84e-07235215193490
Pubmed

Estrogen receptor genotypes influence hot flash prevalence and composite score before and after tamoxifen therapy.

ESR1 ESR2

9.84e-07235219018086
Pubmed

Tamoxifen induces hypercoagulation and alterations in ERα and ERβ dependent on breast cancer sub-phenotype ex vivo.

ESR1 ESR2

9.84e-07235233159119
Pubmed

Phytoestrogens induce differential estrogen receptor alpha- or Beta-mediated responses in transfected breast cancer cells.

ESR1 ESR2

9.84e-07235216118406
Pubmed

Expression of aromatase and estrogen receptors in lumbar motoneurons of mice.

ESR1 ESR2

9.84e-07235228501695
Pubmed

Obesity and disturbed lipoprotein profile in estrogen receptor-alpha-deficient male mice.

ESR1 ESR2

9.84e-07235211095962
Pubmed

Loss of estrogen receptor beta isoform expression and its correlation with aberrant DNA methylation of the 5'-untranslated region in human epithelial ovarian carcinoma.

ESR1 ESR2

9.84e-07235219032364
Pubmed

Estradiol-induced proliferation of papillary and follicular thyroid cancer cells is mediated by estrogen receptors alpha and beta.

ESR1 ESR2

9.84e-07235220372779
Pubmed

ERβ1 Sensitizes and ERβ2 Desensitizes ERα-Positive Breast Cancer Cells to the Inhibitory Effects of Tamoxifen, Fulvestrant and Their Combination with All-Trans Retinoic Acid.

ESR1 ESR2

9.84e-07235236835157
Pubmed

Human permanent tooth sizes are associated with genes encoding oestrogen receptors.

ESR1 ESR2

9.84e-07235232985343
Pubmed

Variants of estrogen receptor alpha and beta genes modify the severity of sporadic breast cancer.

ESR1 ESR2

9.84e-07235228109853
Pubmed

A lack of ovarian function increases neuroinflammation in aged mice.

ESR1 ESR2

9.84e-07235222492304
Pubmed

The distribution of cells containing estrogen receptor-alpha (ERalpha) and ERbeta messenger ribonucleic acid in the preoptic area and hypothalamus of the sheep: comparison of males and females.

ESR1 ESR2

9.84e-07235210919284
Pubmed

Estrogen Receptor Expression in Pancreatic Adenocarcinoma: Time to Reconsider Evidence.

ESR1 ESR2

9.84e-07235234860807
Pubmed

Receptor null mice reveal contrasting roles for estrogen receptor alpha and beta in reproductive tissues.

ESR1 ESR2

9.84e-07235211162937
Pubmed

Estrogen receptor alpha and beta polymorphisms: is there an association with bone mineral density, plasma lipids, and response to postmenopausal hormone therapy?

ESR1 ESR2

9.84e-07235216735942
Pubmed

Estrogen receptor expression and synthesis in the human internal thoracic artery.

ESR1 ESR2

9.84e-07235212597128
Pubmed

Expression of oestrogen receptor-beta in oestrogen receptor-alpha negative human breast tumours.

ESR1 ESR2

9.84e-07235216880783
Pubmed

[Expression of estrogen receptors alpha and beta in human tongue squamous cancer cell and influence of beta-estradiol on the proliferation of tongue cancer cell].

ESR1 ESR2

9.84e-07235221207861
Pubmed

Endogenous estradiol and its association with estrogen receptor gene polymorphisms.

ESR1 ESR2

9.84e-07235216949384
Pubmed

Estrogen receptor genotype and risk of cognitive impairment in elders: findings from the Health ABC study.

ESR1 ESR2

9.84e-07235217889406
Pubmed

Sex steroid hormone polymorphisms, high-density lipoprotein cholesterol, and apolipoprotein A-1 from the Study of Women's Health Across the Nation (SWAN).

ESR1 ESR2

9.84e-07235216949390
Pubmed

The association of bone mineral density with estrogen receptor gene polymorphisms.

ESR1 ESR2

9.84e-07235216949392
Pubmed

Comparative analysis of nuclear estrogen receptor alpha and beta interactomes in breast cancer cells.

ESR1 ESR2

9.84e-07235221173974
Pubmed

Estrogen receptor profiles in human peripheral blood lymphocytes.

ESR1 ESR2

9.84e-07235220542061
Pubmed

Sex differences in exercise-induced physiological myocardial hypertrophy are modulated by oestrogen receptor beta.

ESR1 ESR2

9.84e-07235224654233
Pubmed

DNA-binding ability of NF-kappaB is affected differently by ERalpha and ERbeta and its activation results in inhibition of estrogen responsiveness.

ESR1 ESR2

9.84e-07235218579858
Pubmed

Sex-Specific Involvement of Estrogen Receptors in Behavioral Responses to Stress and Psychomotor Activation.

ESR1 ESR2

9.84e-07235230863326
Pubmed

Estrogen receptor α- (ERα), but not ERβ-signaling, is crucially involved in mechanostimulation of bone fracture healing by whole-body vibration.

ESR1 ESR2

9.84e-07235229367057
Pubmed

Immunohistochemical expression of estrogen receptors alpha and beta in lobular neoplasia.

ESR1 ESR2

9.84e-07235217924141
Pubmed

Differential expression of estrogen receptor α and β isoforms in multiple and solitary leiomyomas.

ESR1 ESR2

9.84e-07235226529545
Pubmed

Roles of estrogen receptor α and β in the regulation of proliferation in endometrial carcinoma.

ESR1 ESR2

9.84e-07235232853964
Pubmed

Localization of estrogen and androgen receptors in male reproductive tissues of mice and rats.

ESR1 ESR2

9.84e-07235215278948
Pubmed

Estrogen Receptors and Endometriosis.

ESR1 ESR2

9.84e-07235232316608
Pubmed

Pregnancy and oestrogen regulate sinoatrial node calcium homeostasis and accelerate pacemaking.

ESR1 ESR2

9.84e-07235229800268
Pubmed

The differential fate of mesonephric tubular-derived efferent ductules in estrogen receptor-alpha knockout versus wild-type female mice.

ESR1 ESR2

9.84e-07235211014235
Pubmed

17Beta-estradiol regulation of the mRNA expression of T-type calcium channel subunits: role of estrogen receptor alpha and estrogen receptor beta.

ESR1 ESR2

9.84e-07235219003958
Pubmed

Effect of oestrogen receptors on brain NMDA receptors of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice.

ESR1 ESR2

9.84e-07235222672467
Pubmed

Estrogen receptors α and β have different gender-dependent effects on the adaptive responses to load bearing in cancellous and cortical bone.

ESR1 ESR2

9.84e-07235222416084
Pubmed

Differential expression patterns and clinical significance of estrogen receptor-α and β in papillary thyroid carcinoma.

ESR1 ESR2

9.84e-07235224884830
Pubmed

Phytoestrogen-mediated inhibition of proliferation of the human T47D breast cancer cells depends on the ERalpha/ERbeta ratio.

ESR1 ESR2

9.84e-07235218955141
Pubmed

Estrogen receptor-beta mediates male-female differences in the development of pressure overload hypertrophy.

ESR1 ESR2

9.84e-07235215374829
Pubmed

Expression of oestrogen receptors, ERalpha, ERbeta, and ERbeta variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERalpha.

ESR1 ESR2

9.84e-07235219758455
Pubmed

Bioassays for estrogenic activity: development and validation of estrogen receptor (ERalpha/ERbeta) and breast cancer proliferation bioassays to measure serum estrogenic activity in clinical studies.

ESR1 ESR2

9.84e-07235219382890
Pubmed

Variants in estrogen receptor alpha gene are associated with phenotypical expression of obsessive-compulsive disorder.

ESR1 ESR2

9.84e-07235220850223
Pubmed

Estradiol induces proliferation of keratinocytes via a receptor mediated mechanism.

ESR1 ESR2

9.84e-07235215208259
Pubmed

The influence of ESR1 rs9340799 and ESR2 rs1256049 polymorphisms on prostate cancer risk.

ESR1 ESR2

9.84e-07235224859835
Pubmed

Support of a bi-faceted role of estrogen receptor β (ERβ) in ERα-positive breast cancer cells.

ESR1 ESR2

9.84e-07235224192230
Pubmed

Gender-specific effects of endogenous testosterone: female alpha-estrogen receptor-deficient C57Bl/6J mice develop glomerulosclerosis.

ESR1 ESR2

9.84e-07235217495854
Pubmed

Effects of estrogen on the vascular injury response in estrogen receptor alpha, beta (double) knockout mice.

ESR1 ESR2

9.84e-07235211557741
Pubmed

Transgenic models of metabolic bone disease: impact of estrogen receptor deficiency on skeletal metabolism.

ESR1 ESR2

9.84e-07235212952206
Pubmed

Determination of the isoflavone composition and estrogenic activity of commercial dietary supplements based on soy or red clover.

ESR1 ESR2

9.84e-07235226023053
Pubmed

Estrogen effects on vascular inflammation are age dependent: role of estrogen receptors.

ESR1 ESR2

9.84e-07235224876352
Pubmed

Crosstalk between the estrogen receptor and the HER tyrosine kinase receptor family: molecular mechanism and clinical implications for endocrine therapy resistance.

ESR1 ESR2

9.84e-07235218216219
Pubmed

Both estrogen receptor-alpha and -beta are required for sexual differentiation of the anteroventral periventricular area in mice.

ESR1 ESR2

9.84e-07235216239299
Pubmed

Global transcription profiling of estrogen activity: estrogen receptor alpha regulates gene expression in the kidney.

ESR1 ESR2

9.84e-07235212538633
Pubmed

Estrogen receptor beta-deficient female mice develop a bladder phenotype resembling human interstitial cystitis.

ESR1 ESR2

9.84e-07235217522255
Pubmed

Ratio of Circulating Estrogen Receptors Beta and Alpha (ERβ/ERα) Indicates Endoscopic Activity in Patients with Crohn's Disease.

ESR1 ESR2

9.84e-07235228823012
Pubmed

Estrogen receptor polymorphisms and the vascular effects of hormone therapy.

ESR1 ESR2

9.84e-07235221106950
Pubmed

Untangling the human estrogen receptor gene structure.

ESR1 ESR2

9.84e-07235212111450
Pubmed

Generation and reproductive phenotypes of mice lacking estrogen receptor beta.

ESR1 ESR2

9.84e-0723529861029
Pubmed

Molecular analysis of the estrogen receptor alpha gene in men with coronary artery disease: association with disease status.

ESR1 ESR2

9.84e-07235212691862
Pubmed

Association of promoter methylation of ERα and ERβ with sporadic breast cancer--a study from North India.

ESR1 ESR2

9.84e-07235224833090
Pubmed

Critical role for estrogen receptor alpha in negative feedback regulation of gonadotropin-releasing hormone mRNA expression in the female mouse.

ESR1 ESR2

9.84e-07235214583652
Pubmed

Long-Term Neonatal Estrogen Exposure Causes Irreversible Inhibition of LH Pulses by Suppressing Arcuate Kisspeptin Expression via Estrogen Receptors α and β in Female Rodents.

ESR1 ESR2

9.84e-07235228368450
Pubmed

Estrogen receptor beta mediates gender differences in ischemia/reperfusion injury.

ESR1 ESR2

9.84e-07235215698835
Pubmed

Mechanisms of naringenin-induced apoptotic cascade in cancer cells: involvement of estrogen receptor alpha and beta signalling.

ESR1 ESR2

9.84e-07235215545229
Pubmed

The oxidative stress in breast tumors of postmenopausal women is ERα/ERβ ratio dependent.

ESR1 ESR2

9.84e-07235223499841
Pubmed

Estrogen receptor beta gene variants may be associated with more favorable metabolic profile in postmenopausal women undergoing coronary angiography.

ESR1 ESR2

9.84e-07235219938352
Pubmed

Exploring the association of ESR1 and ESR2 gene SNPs with polycystic ovary syndrome in human females: a comprehensive association study.

ESR1 ESR2

9.84e-07235238281964
Pubmed

Estrogen receptors alpha and beta mediate different aspects of the facilitatory effects of female cues on male risk taking.

ESR1 ESR2

9.84e-07235218374493
InteractionRSPH4A interactions

C8A RSPH1

7.32e-063322int:RSPH4A
InteractionSDC1 interactions

ERMAP HGF ESR1 ESR2

7.61e-0680324int:SDC1
InteractionNCAM2 interactions

RSPH1 ESR1 ESR2

1.43e-0530323int:NCAM2
InteractionUSP7 interactions

USP36 USP44 WDR1 RSPH1 TRIM22 MYO10 ESR1 ESR2 HHAT TMEM40

2.29e-0513133210int:USP7
InteractionMSL3B interactions

ESR1 ESR2

2.44e-055322int:MSL3B
InteractionDNASE1L1 interactions

ATRN ESR1 HYAL2 ESR2

3.78e-05120324int:DNASE1L1
InteractionLAMB2 interactions

CRISP2 VWCE ESR1 ESR2

4.03e-05122324int:LAMB2
InteractionC11orf98 interactions

USP36 ESR1 ESR2

4.61e-0544323int:C11orf98
InteractionCMAS interactions

USP36 RSPH1 ESR1 ESR2

4.72e-05127324int:CMAS
InteractionNHP2 interactions

USP36 RSPH1 ESR1 ESR2

5.32e-05131324int:NHP2
InteractionPIEZO1 interactions

IFNGR2 ESR1 ESR2

5.62e-0547323int:PIEZO1
InteractionALKBH5 interactions

USP36 ESR1 ESR2

6.77e-0550323int:ALKBH5
InteractionSAA1 interactions

USP36 COL4A2 EMC8

8.54e-0554323int:SAA1
InteractionP4HA1 interactions

COL4A2 COL8A1 EMC8 ESR1 COX14

9.92e-05298325int:P4HA1
InteractionEXOSC5 interactions

USP36 ESR1 ESR2 SHISA6

1.27e-04164324int:EXOSC5
InteractionISG20L2 interactions

USP36 ESR1 ESR2

1.35e-0463323int:ISG20L2
InteractionWDR55 interactions

USP36 ESR1 ESR2

1.35e-0463323int:WDR55
InteractionPRSS8 interactions

ESR1 HYAL2 ESR2

1.42e-0464323int:PRSS8
InteractionCSRP1 interactions

MYO10 ESR1 ESR2

1.49e-0465323int:CSRP1
InteractionPTPRK interactions

COL4A2 ATRN HYAL2 ESR2

1.71e-04177324int:PTPRK
InteractionEMC6 interactions

NADSYN1 EMC8 ESR2

1.77e-0469323int:EMC6
InteractionZHX2 interactions

USP49 ESR1 ESR2

1.77e-0469323int:ZHX2
InteractionCORO1C interactions

USP36 EMC8 RSPH1 ESR1 ESR2

1.79e-04338325int:CORO1C
InteractionDHX33 interactions

USP36 ESR1 ESR2

1.85e-0470323int:DHX33
InteractionCRACDL interactions

ESR1 ESR2

1.88e-0413322int:CRACDL
InteractionRCE1 interactions

ESR1 ESR2

1.88e-0413322int:RCE1
InteractionESF1 interactions

USP36 COL8A1 ESR1 ESR2

1.90e-04182324int:ESF1
InteractionDDX49 interactions

USP36 ESR1 ESR2

2.01e-0472323int:DDX49
InteractionPOP4 interactions

USP36 ESR1 ESR2

2.01e-0472323int:POP4
InteractionCEACAM5 interactions

ESR1 ESR2

2.20e-0414322int:CEACAM5
InteractionRHBDF1 interactions

ESR1 ESR2

2.53e-0415322int:RHBDF1
InteractionTDRKH interactions

ESR1 ESR2 COX14

2.55e-0478323int:TDRKH
InteractionMBD4 interactions

RSPH1 ESR1 ESR2

2.85e-0481323int:MBD4
InteractionPALM3 interactions

ESR1 ESR2

2.89e-0416322int:PALM3
InteractionELAPOR1 interactions

ESR1 ESR2

2.89e-0416322int:ELAPOR1
InteractionKRR1 interactions

USP36 USP44 USP49 ESR1 ESR2

3.04e-04379325int:KRR1
InteractionDNAJB6 interactions

USP36 DYSF MYO10 ESR1 ESR2

3.04e-04379325int:DNAJB6
InteractionKARS1 interactions

EMC8 DYSF ESR1 ESR2 COX14

3.19e-04383325int:KARS1
InteractionGALNT3 interactions

ESR1 ESR2

3.27e-0417322int:GALNT3
InteractionNT5E interactions

USP36 ESR1 ESR2

3.29e-0485323int:NT5E
InteractionPOLRMT interactions

USP36 VWCE ESR1 ESR2

3.34e-04211324int:POLRMT
InteractionDROSHA interactions

USP36 ESR1 ESR2

3.52e-0487323int:DROSHA
InteractionFBXO45 interactions

USP49 MYO10 ESR1

3.64e-0488323int:FBXO45
InteractionCYP1B1 interactions

ESR1 ESR2

3.68e-0418322int:CYP1B1
InteractionTMEM50A interactions

ESR1 ESR2

3.68e-0418322int:TMEM50A
InteractionZNF146 interactions

VWCE ESR1 ESR2

4.02e-0491323int:ZNF146
InteractionNOP10 interactions

USP36 ESR1 ESR2

4.02e-0491323int:NOP10
InteractionCAMK2D interactions

IFNGR2 MYO10 ESR2 SHISA6

4.05e-04222324int:CAMK2D
InteractionUAP1L1 interactions

WDR1 RSPH1

4.11e-0419322int:UAP1L1
InteractionCD59 interactions

C8A ESR1 ESR2

4.15e-0492323int:CD59
InteractionMICU1 interactions

ESR1 ESR2 COX14

4.28e-0493323int:MICU1
InteractionACKR3 interactions

ESR1 ESR2

4.56e-0420322int:ACKR3
InteractionMAP3K20 interactions

COL8A1 ESR1 ESR2

5.14e-0499323int:MAP3K20
InteractionB3GAT3 interactions

ESR1 HYAL2 ESR2

5.14e-0499323int:B3GAT3
InteractionSPTY2D1 interactions

USP36 ESR1 ESR2

5.14e-0499323int:SPTY2D1
InteractionNME3 interactions

ESR1 ESR2 COX14

5.30e-04100323int:NME3
InteractionCXXC5 interactions

RSPH1 ESR1

5.53e-0422322int:CXXC5
InteractionURB2 interactions

USP36 ESR1 ESR2

5.77e-04103323int:URB2
InteractionWDR75 interactions

USP36 ESR1 ESR2

5.94e-04104323int:WDR75
InteractionCREB3L4 interactions

ESR1 ESR2

6.05e-0423322int:CREB3L4
InteractionCDYL2 interactions

ESR1 ESR2

6.05e-0423322int:CDYL2
InteractionBMP2K interactions

COL8A1 ESR1 ESR2

6.11e-04105323int:BMP2K
InteractionDHX40 interactions

USP36 ZNF318 ESR1 ESR2

6.23e-04249324int:DHX40
InteractionNDUFS8 interactions

EMC8 ESR1 ESR2 COX14

6.33e-04250324int:NDUFS8
InteractionMYO19 interactions

WDR1 MYO10 ESR1 ESR2

6.52e-04252324int:MYO19
InteractionKLK9 interactions

ESR1 ESR2

6.60e-0424322int:KLK9
InteractionCLDN3 interactions

ESR1 ESR2

6.60e-0424322int:CLDN3
InteractionCD58 interactions

ESR1 ESR2

6.60e-0424322int:CD58
InteractionTBC1D30 interactions

ESR1 ESR2

6.60e-0424322int:TBC1D30
InteractionPDLIM2 interactions

ESR1 ESR2

6.60e-0424322int:PDLIM2
InteractionDDX51 interactions

USP36 ESR1 ESR2

6.63e-04108323int:DDX51
InteractionUSP30 interactions

ESR1 ESR2 COX14

6.81e-04109323int:USP30
InteractionRRP7A interactions

USP36 ESR1 ESR2

6.99e-04110323int:RRP7A
InteractionUTP15 interactions

USP36 ESR1 ESR2

6.99e-04110323int:UTP15
InteractionPPP6R3 interactions

USP36 USP49 MYO10 ESR1

7.12e-04258324int:PPP6R3
InteractionTMCC1 interactions

ESR1 ESR2

7.16e-0425322int:TMCC1
InteractionGRHL2 interactions

ESR1 ESR2

7.16e-0425322int:GRHL2
InteractionSKIC2 interactions

WDR1 ESR1 ESR2

7.18e-04111323int:SKIC2
InteractionEXOSC1 interactions

USP36 ESR1 ESR2

7.37e-04112323int:EXOSC1
InteractionCCDC59 interactions

USP36 ESR1 ESR2

7.37e-04112323int:CCDC59
InteractionIMP4 interactions

USP36 ESR1 ESR2

7.56e-04113323int:IMP4
InteractionEMG1 interactions

USP36 ESR1 ESR2

7.56e-04113323int:EMG1
InteractionRSBN1L interactions

USP36 ESR1 ESR2

7.76e-04114323int:RSBN1L
InteractionPEX13 interactions

IFNGR2 ESR2

8.36e-0427322int:PEX13
InteractionINO80D interactions

ESR1 ESR2

8.36e-0427322int:INO80D
InteractionSPIRE1 interactions

ESR1 ESR2

8.36e-0427322int:SPIRE1
InteractionNOL11 interactions

USP36 ESR1 ESR2

8.79e-04119323int:NOL11
InteractionSPATS2 interactions

USP36 ESR1 ESR2

8.79e-04119323int:SPATS2
InteractionNGDN interactions

USP36 ESR1 ESR2

8.79e-04119323int:NGDN
InteractionPSMC5 interactions

USP36 USP44 USP49 ESR1 ESR2

9.22e-04484325int:PSMC5
InteractionINTS15 interactions

ESR1 ESR2

9.65e-0429322int:INTS15
InteractionTBC1D10A interactions

ESR1 ESR2

9.65e-0429322int:TBC1D10A
InteractionGEMIN2 interactions

ERMAP ESR1 ESR2

1.04e-03126323int:GEMIN2
InteractionRCL1 interactions

USP36 ESR1 ESR2

1.04e-03126323int:RCL1
InteractionDST interactions

WDR1 RSPH1 ESR1 ESR2

1.06e-03287324int:DST
InteractionEXOSC7 interactions

USP36 ESR1 ESR2

1.06e-03127323int:EXOSC7
InteractionCHD1 interactions

USP36 ESR1 ESR2

1.06e-03127323int:CHD1
InteractionNOL8 interactions

USP36 ESR1 ESR2

1.08e-03128323int:NOL8
InteractionNRDE2 interactions

ESR1 ESR2

1.10e-0331322int:NRDE2
InteractionIFRD2 interactions

USP36 ESR1

1.10e-0331322int:IFRD2
Cytoband1p34.2

ERMAP MFSD2A

9.29e-04573621p34.2
Cytoband11q13.4

C2CD3 NADSYN1

1.60e-037536211q13.4
GeneFamilyUbiquitin specific peptidases

USP36 USP44 USP49

5.44e-0556243366
GeneFamilyCollagens

COL4A2 COL8A1

1.69e-0346242490
GeneFamilyNuclear hormone receptors

ESR1 ESR2

1.91e-034924271
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-4|TCGA-Lung / Sample_Type by Project: Shred V9

COL8A1 DYSF PTTG1IP2 ESR1

1.21e-051763640923b01137d6f9956ca815b41102c81e82624065
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MYO10 ESR1 ESR2 SHISA6

1.29e-0517936414fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 MFSD2A MYO10 HYAL2

1.92e-051983640a4626b51ba8b52acbaf616f0ced850079cd7149
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 MFSD2A DYSF HYAL2

1.92e-0519836472e8b9cccb7b0a2ea9d415218fff4fa2f09728f4
ToppCellmetastatic_Brain-Endothelial_cells-Tumor_ECs|metastatic_Brain / Location, Cell class and cell subclass

COL4A2 MFSD2A DYSF HYAL2

1.92e-051983645e274f29cc796dae7d64d6035e904816c25f9914
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 HGF MYO10 HYAL2

1.92e-05198364f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCellmetastatic_Brain-Endothelial_cells|metastatic_Brain / Location, Cell class and cell subclass

COL4A2 MFSD2A DYSF HYAL2

1.92e-0519836497ef7946ef11ac93318c1dd46b548dc01e5a6aba
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 MFSD2A DYSF HYAL2

1.96e-051993649c40b3ee39860e9d8edafd007daec11abdd95435
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 MFSD2A DYSF HYAL2

1.96e-051993640602e2b2aa56d106da63bd342a38bef437b4d496
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 MFSD2A DYSF HYAL2

1.96e-05199364463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 MFSD2A DYSF HYAL2

1.96e-0519936472b34bce8157abe389e95cd3ed8ba578dce0cbf6
ToppCellControl_saline-Endothelial-Endothelial-Gen_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

COL4A2 DYSF TRIM22 HYAL2

2.00e-052003643b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-11|TCGA-Brain / Sample_Type by Project: Shred V9

COL8A1 IGHV4-34 ESR2

1.46e-041273637c3f8c791567fff5d2f42c2c7d09c78ec6ca3afe
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rxfp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL8A1 SHISA6 TMEM40

1.61e-0413136381efe8b0ca4377e557a42ddb12aecaf3f46b15bf
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Tmem163_Dmrtb1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DYSF RSPH1 TMEM40

1.79e-041363630376c2907b869c7d42f57af7f65ffdd6246c4d27
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Astrocyte|GW09 / Sample Type, Dataset, Time_group, and Cell type.

ERMAP COL4A2 USP49

2.04e-0414236385e573616e54d41391b4ad8c3d38e4ca92112673
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-type_I_NK_T_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

USP49 ATRN TMEM145

2.21e-04146363447c05414eda71681a0c07baba900f88ed6165ed
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col18a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HGF DYSF TMEM40

2.30e-04148363fc80c02b51cf55a04ce550838ee2f41d8f656f41
ToppCellfrontal_cortex|World / Per Region, Lineage, Cell class, Cell type, Cell subtype

HGF DYSF TMEM40

2.49e-04152363f9c29d4568402ca07a717dbffb3ccc7f35c5fe56
ToppCellControl-Endothelial_cells-Inflamed_endothelial_cells|Control / group, cell type (main and fine annotations)

COL4A2 DYSF HYAL2

2.89e-04160363958256e3d3836160763b82bb48f794087918d935
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

USP49 TRIM22 ESR2

3.00e-04162363768a566e76923323c1f197f60bab472a8784490b
ToppCellCiliated_cells-A-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

CRISP2 RSPH1 SHISA6

3.05e-0416336343194c6127df1ce3d29242f719645de3c11fd7c0
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 MFSD2A HYAL2

3.57e-04172363c3a99828838af3b85c8c885d69cc8018f55ced50
ToppCellEndothelial-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 DYSF HYAL2

3.57e-041723638a527dff06d841a86c7eb04a1dd9630787294da4
ToppCelldroplet-Fat-Mat-18m-Hematologic-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF NADSYN1 TMEM40

3.82e-04176363867936a20f73f638055c19c8d88834aa2cc657cf
ToppCellfacs-Heart-LV|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DYSF MYO10

3.82e-04176363483e36d9bb7268bf179e69a65e1a0be099035162
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 HGF COL8A1

3.88e-04177363cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 DYSF HYAL2

3.88e-0417736312f8627124acbf436e75681ff1ce429ff5e3f256
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 HGF COL8A1

3.88e-04177363db222faaecbe5600da39277243c4e7e764eb63c9
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

USP44 HGF C8A

3.88e-0417736391706bd0d4dda8d98843fb00b898d5aca4d66b64
ToppCelltumor_Lung-Endothelial_cells-EPCs|tumor_Lung / Location, Cell class and cell subclass

COL4A2 ZNF318 HYAL2

3.88e-04177363f8b152c09d56a97e8c0482fb1a3964c05f9dc8c5
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 DYSF HYAL2

3.88e-04177363fdf2af00fc971f0cd3915e1416e4a256458d6ea8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DYSF HYAL2 TMEM145

3.95e-041783635636f2e89027955f406d420ff6df6a4b8c12cb20
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DYSF MYO10

3.95e-04178363ba2f0585626988b511046630bc16be5c5fec3fb2
ToppCell390C-Endothelial_cells-Endothelial-E-|390C / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 DYSF HYAL2

3.95e-04178363804ac3725c1f88e2212172bfb9aa01d97a735621
ToppCell390C-Endothelial_cells-Endothelial-E|390C / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 DYSF HYAL2

3.95e-04178363ad6dc4a375664c919bd48c35c48a561fc5a7de8c
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A2 DYSF MYO10

3.95e-04178363a3f95f0002f408b5b6c57e28b297b5b2737e919c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 HGF ESR1

3.95e-0417836378a0c6340001a77f5b2d890b6263f574af2e72da
ToppCellTCGA-Liver-Solid_Tissue_Normal|TCGA-Liver / Sample_Type by Project: Shred V9

HGF MFSD2A ESR1

4.01e-041793637046f0a426e45fe1b41a25721ee1e33f6fc7f9e3
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 DYSF HYAL2

4.01e-041793639fd9b136ecbcbd4e4f0d5875ede98d8d48608afb
ToppCellTCGA-Liver-Solid_Tissue_Normal-Liver|TCGA-Liver / Sample_Type by Project: Shred V9

HGF MFSD2A ESR1

4.01e-041793630e22e840f43ca81a7543dcf33ec17a741cdf7f37
ToppCellTCGA-Liver-Solid_Tissue_Normal-Liver-Liver_normal_tissue|TCGA-Liver / Sample_Type by Project: Shred V9

HGF MFSD2A ESR1

4.01e-0417936317ba1eedb6ebf039d3b11d099351d0ac6363c8d1
ToppCellTCGA-Liver-Solid_Tissue_Normal-Liver-Liver_normal_tissue-2|TCGA-Liver / Sample_Type by Project: Shred V9

HGF MFSD2A ESR1

4.01e-04179363a20bb3ace5be10c5aef330e9268c0ba55f8fee23
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 HGF ESR1

4.08e-04180363fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 COL8A1 SHISA6

4.08e-04180363f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCelldroplet-Lung-nan-18m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 COL8A1 SHISA6

4.08e-04180363dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 HGF ESR1

4.08e-04180363280ff5c8f292be1b88120db5ff1788b750644856
ToppCellAT1-AT2_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 USP44 COL8A1

4.15e-04181363ca23ce4f2c7b684d8ddd0e8619b3b696023d75e3
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(other)|COVID-19 / group, cell type (main and fine annotations)

COL4A2 HYAL2 TMEM145

4.15e-0418136326eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high|PND07-28-samps / Age Group, Lineage, Cell class and subclass

COL4A2 DYSF HYAL2

4.15e-041813639cd5e5c285c2b628db9d59709af053defd7c0aff
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 HGF COL8A1

4.15e-04181363c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 HGF COL8A1

4.15e-04181363c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCelldroplet-Fat-Scat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERMAP MYO10 KCNV2

4.21e-04182363fea094fe0e7796c084e60b5310c1559658633f7a
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-Late_cap|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

COL4A2 DYSF HYAL2

4.28e-041833633e69cc605f166a1f04e3d077935f7cfd806f1ffd
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL8A1 HYAL2 ESR2

4.35e-04184363087666ba949b129c53d7ace40f9e543e3875a7de
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HGF COL8A1 ESR1

4.35e-04184363c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCellnormal_Lung-Endothelial_cells-Tumor_ECs|normal_Lung / Location, Cell class and cell subclass

COL4A2 DYSF HYAL2

4.35e-041843637ee98acda030366ac6cf3890a6d93fd0426712ed
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HGF DYSF HYAL2

4.42e-04185363241ea1e178fffef9e7df971de739e794332d5173
ToppCellEndothelial-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 DYSF HYAL2

4.42e-04185363133c9dc64d564dae4aeeeca22f386aa3f13fa980
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HGF DYSF HYAL2

4.49e-041863639579180db2a0bf3f043b4d169f9a08cdc45b459a
ToppCellControl-Endothelial_cells-Endothelial_cells_(other)|Control / group, cell type (main and fine annotations)

COL4A2 DYSF HYAL2

4.49e-04186363c6075fe84226b370c5139066793844ad33ae2db1
ToppCelldroplet-Heart-nan-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DYSF MYO10

4.49e-0418636349ad01d216860a2bd4d63905a7064471b02f2b37
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

USP36 USP49 ESR2

4.49e-04186363927723ad579bbd9947ff525bd501e222d3fa9289
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|356C / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 DYSF HYAL2

4.49e-04186363f0b78c7ee20279970ea8961bf59acb5262f2dce5
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

COL8A1 VWCE HHAT

4.49e-041863634d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCell10x5'-GI_small-bowel-Myeloid_Monocytic-Nonclassical_monocytes|GI_small-bowel / Manually curated celltypes from each tissue

IFNGR2 HGF MFSD2A

4.49e-04186363a16ecf70271894a842925f232009e2623d16947e
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 HGF MYO10

4.49e-04186363888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|356C / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 DYSF HYAL2

4.49e-041863632b3c814a7dee8286ea113c63dc3de5daf0257d37
ToppCellControl-Endothelial_cells-Endothelial_cells_(general)|Control / group, cell type (main and fine annotations)

COL4A2 DYSF HYAL2

4.56e-04187363fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DYSF MYO10 HYAL2

4.56e-0418736325efb82afe863a853ecdd781ad89026c993aaa67
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL4A2 HGF ESR1

4.56e-0418736376bfe8c42430a230a8bdf299575c444fb7780f24
ToppCelltumor_Lung-Endothelial_cells-Lymphatic_ECs|tumor_Lung / Location, Cell class and cell subclass

COL4A2 DYSF HYAL2

4.56e-0418736387ecdc5f24aced95a37e653429f0fc493ff4aa3e
ToppCellwk_15-18-Hematologic_Lymphocytic-B-small_pre-B-II_cell|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TRIM22 IGHV4-34 IGHV1-2

4.63e-0418836356d78b5a86a71b2e752db379f4a46dc4c623b553
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D122|Adult / Lineage, Cell type, age group and donor

COL4A2 DYSF HYAL2

4.63e-0418836302a62888e9db29d20133eeca1686d302545a39c9
ToppCellfacs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DYSF MYO10

4.63e-04188363e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCelldroplet-Heart-nan-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DYSF MYO10

4.63e-041883639dfa2e0b73640459cdf88277291e3ab9c33e0217
ToppCellfacs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DYSF MYO10

4.63e-04188363ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCellfacs-Heart-LV-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DYSF MYO10

4.63e-041883630fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 DYSF HYAL2

4.63e-041883630026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DYSF MYO10 HYAL2

4.70e-04189363db09d591b885ce2bc9e353f08b6694e2192582e1
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IFNGR2 HGF HYAL2

4.70e-0418936354a45b0cb7dea01caf1cf0a2664c40e5779a0b61
ToppCellfacs-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DYSF MYO10

4.70e-04189363e3d65417997bdd3f9c312c0977dceb6eca061029
ToppCellfacs-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DYSF MYO10

4.70e-041893635559af03d9d612bb8dcf825e45744a9f8332bac8
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IFNGR2 HGF HYAL2

4.70e-04189363a2f4f1dd5452f7efb7427919a0b90875cf2e1dc7
ToppCellfacs-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DYSF MYO10

4.70e-04189363f60ac60ab9b317a0196f0cbbe520ef7dbd19ac11
ToppCellEndothelial-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 DYSF HYAL2

4.70e-0418936304b565855f58ca0f343904d04be657b66e109076
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Lymphatic|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

COL4A2 DYSF HYAL2

4.78e-041903638d6ec2fc0af19a5cb16fff34f8b131b71b33d45f
ToppCellfacs-Heart-RV-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DYSF MYO10

4.78e-0419036389d1d686cc683206534e2157554d7d0df5d53497
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHV4-34 ESR2 IGHV1-2

4.78e-0419036379ee6d10dfbb775da149a1104da5823cf63bbb46
ToppCell10x3'2.3-week_17-19-Hematopoietic-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

WDR1 RSPH1 TMEM40

4.78e-0419036364060e4b56ac9989e659c2d5d2a6b6edeba4d8d4
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DYSF MYO10

4.78e-04190363bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DYSF MYO10

4.78e-04190363d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 MFSD2A HYAL2

4.78e-0419036306bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCell21-Trachea-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

COL4A2 DYSF HYAL2

4.78e-04190363bce09634acbc2cfd53666328e8aed8bf8835f845
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHV4-34 ESR2 IGHV1-2

4.78e-0419036318762ce78ed0b206ade19e1c8ff76a2647489f68
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DYSF MYO10

4.78e-0419036338a815abf0ac5cac6071737cadc54a514f62d37d
ToppCell21-Trachea-Endothelial-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

COL4A2 DYSF HYAL2

4.78e-0419036308437396a98ca9526f69c3a74bbf2929f3c68b8e
ToppCellfacs-Heart-RV-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DYSF MYO10

4.78e-0419036365ba6c4f4a2905c0bf4ff99518ae49e3dfd5e640
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HGF COL8A1 ESR1

4.85e-0419136339092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellfacs-Heart-LA-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 DYSF MYO10

4.85e-04191363827be47d3574c6c5b021c6f1c1670834344f10cb
Drug5-octylphenol

ESR1 ESR2

2.04e-062332ctd:C113977
DrugPyrazolo[1,5-a]pyrimidine, 12d

ESR1 ESR2

2.04e-062332CID016103245
DrugPyrazolo[1,5-a]pyrimidine, 12c

ESR1 ESR2

2.04e-062332CID016103238
Drugtetradifon

ESR1 ESR2

2.04e-062332ctd:C005807
DrugSureCN3587271

ESR1 ESR2

2.04e-062332CID011208678
DrugCNP-amino

ESR1 ESR2

2.04e-062332CID000033473
DrugERB 041

ESR1 ESR2

2.04e-062332ctd:C478102
Drugetocrylene

ESR1 ESR2

2.04e-062332CID000243274
Drug(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL

ESR1 ESR2

2.04e-062332DB07933
Drug4-(4-hydroxyphenyl)-6-methyl-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol

ESR1 ESR2

2.04e-062332CID010125512
DrugRaloxifene

ESR1 ESR2

2.04e-062332DB00481
DrugBrn 0187733

ESR1 ESR2

2.04e-062332CID000160446
Drug2-phenylbenzofuran

ESR1 ESR2

2.04e-062332CID003517936
DrugPHTPP

ESR1 ESR2

2.04e-062332CID011201035
Drugbutolame

ESR1 ESR2

2.04e-062332CID000197608
DrugLY 326315

ESR1 ESR2

2.04e-062332CID009803972
DrugJK 1624F2-1

ESR1 ESR2

2.04e-062332ctd:C113642
Drugsteroid C

ESR1 ESR2

2.04e-062332CID000454473
Drug2z4b

ESR1 ESR2

2.04e-062332CID011197931
Drugoctocrylene

ESR1 ESR2

2.04e-062332ctd:C088673
DrugO-desmethylangolensin

ESR1 ESR2

2.04e-062332ctd:C050052
Drugdehydroestrone

ESR1 ESR2

2.04e-062332CID000102225
Drug(3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL

ESR1 ESR2

2.04e-062332DB07638
DrugCHEMBL397775

ESR1 ESR2

2.04e-062332CID010214678
Drugprolame

ESR1 ESR2

2.04e-062332CID000127441
Drugbenzohydrol

ESR1 ESR2

2.04e-062332ctd:C020225
Drugparthenocissin A

ESR1 ESR2

2.04e-062332ctd:C549189
DrugCyclohexanone, 3b

ESR1 ESR2

2.04e-062332CID011370317
DrugCHEBI:428946

ESR1 ESR2

2.04e-062332CID011688293
DrugF ppt

ESR1 ESR2

2.04e-062332CID003035869
DrugCHEMBL234633

ESR1 ESR2

2.04e-062332CID010192968
DrugSureCN14514707

ESR1 ESR2

2.04e-062332CID010192967
DrugSureCN3118249

ESR1 ESR2

2.04e-062332CID011519653
DrugSureCN4017709

ESR1 ESR2

2.04e-062332CID011256602
DrugCHEBI:428959

ESR1 ESR2

2.04e-062332CID011638242
DrugDNC005795

ESR1 ESR2

2.04e-062332CID011638264
Drugtetrahydrodaidzein

ESR1 ESR2

2.04e-062332ctd:C433164
Drugtri-(2-ethylhexyl)trimellitate

ESR1 ESR2

2.04e-062332ctd:C036101
Drug2-chloro-4-phenylphenol

ESR1 ESR2

2.04e-062332ctd:C012257
Drug2,2,4-trimethyl-1,3-pentanediol diisobutyrate

ESR1 ESR2

2.04e-062332ctd:C001508
Drug2-(3-chloro-4-hydroxyphenyl)-2-(4-hydroxyphenyl)propane

ESR1 ESR2

2.04e-062332ctd:C497826
Drug2,2-bis(3-chloro-4-hydroxyphenyl)propane

ESR1 ESR2

2.04e-062332ctd:C497827
Drug1-ethyl-2-(4-hydroxyphenyl)-3H-inden-5-ol

ESR1 ESR2

2.04e-062332CID011615788
DrugSureCN3593776

ESR1 ESR2

2.04e-062332CID009948127
DrugSureCN14047367

ESR1 ESR2

2.04e-062332CID010171723
Drug(4R)-6-(ethoxymethyl)-4-(4-hydroxyphenyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol

ESR1 ESR2

2.04e-062332CID011175195
DrugY134 compound

ESR1 ESR2

2.04e-062332ctd:C518540
DrugTS 108

ESR1 ESR2

2.04e-062332ctd:C482068
Drug(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL

ESR1 ESR2

2.04e-062332DB08020
Drugethyl cinnamate

ESR1 ESR2

2.04e-062332ctd:C451418
Drug(4R)-4-(4-hydroxyphenyl)-6-methylol-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol

ESR1 ESR2

2.04e-062332CID011174414
DrugEstriol

ESR1 ESR2

2.04e-062332DB04573
DrugEstropipate

ESR1 ESR2

2.04e-062332DB04574
DrugCHEBI:428952

ESR1 ESR2

2.04e-062332CID011674420
Drugphytoene

ESR1 ESR2

2.04e-062332ctd:C100185
Drug6-(4-hydroxyphenyl)-6,6a,7,8,9,10,11,11a-octahydrocyclohepta[c]chromen-2-ol

ESR1 ESR2

2.04e-062332CID010215026
Drug4-(2-chloro-4-(2-piperidin-1-ylethoxy)phenyl)-5-(2,6-dichloro-4-hydroxyphenyl)-2-imidazoline

ESR1 ESR2

2.04e-062332ctd:C496952
DrugCHEMBL48352

ESR1 ESR2

2.04e-062332CID011522286
Drugbromophos

ESR1 ESR2

2.04e-062332ctd:C100092
Drugindenestrol

ESR1 ESR2

2.04e-062332ctd:C047437
DrugSureCN14514705

ESR1 ESR2

2.04e-062332CID010125414
Drug[5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE

ESR1 ESR2

2.04e-062332DB06927
Drug3,4-dihydroxybenzaldoxime

ESR1 ESR2

2.04e-062332ctd:C053286
DrugTamoxifen

ESR1 ESR2

2.04e-062332DB00675
DrugSureCN14514737

ESR1 ESR2

2.04e-062332CID010149292
Drugdi-(5-methylhexyl)phthalate

ESR1 ESR2

2.04e-062332ctd:C042791
Drugphytofluene

ESR1 ESR2

2.04e-062332ctd:C003140
DrugLY2066948

ESR1 ESR2

2.04e-062332CID005327043
Drug1x7e

ESR1 ESR2

2.04e-062332CID000656953
DrugSERBA-2

ESR1 ESR2

2.04e-062332CID009925763
DrugSureCN1360427

ESR1 ESR2

2.04e-062332CID011720174
Drugsalicylaldoxime

ESR1 ESR2

2.04e-062332ctd:C005704
Drug16 alpha-iodoestradiol

ESR1 ESR2

2.04e-062332ctd:C024871
Drugbenzophenone-6

ESR1 ESR2

6.11e-063332CID000008570
Drugdichlofenthion

ESR1 ESR2

6.11e-063332CID000007328
Drug2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid

ESR1 ESR2

6.11e-063332ctd:C101851
DrugNafoxidine

ESR1 ESR2

6.11e-063332ctd:D009256
DrugLY2066948

ESR1 ESR2

6.11e-063332ctd:C504960
DrugCHF 4056

ESR1 ESR2

6.11e-063332ctd:C450419
DrugDiethylstilbestrol

ESR1 ESR2

6.11e-063332DB00255
DrugAC1LGHHD

ESR1 ESR2

6.11e-063332CID000821427
Drugcyanophenphos

ESR1 ESR2

6.11e-063332ctd:C002488
Drugp-tert-amylphenol

ESR1 ESR2

6.11e-063332ctd:C019566
Drug1-(4-nitro-2-(trifluoromethyl)phenyl)-4-(3-(trifluoromethyl)phenyl)piperazine

ESR1 ESR2

6.11e-063332ctd:C562246
DrugChromans

ESR1 ESR2

6.11e-063332ctd:D002839
Drug2,4,6-trichlorophenyl-4'-aminophenyl ether

ESR1 ESR2

6.11e-063332ctd:C067259
Drug7alpha-methyl-17alpha-ethynylestradiol

ESR1 ESR2

6.11e-063332ctd:C475050
Drug4-hydroxybenzophenone

ESR1 ESR2

6.11e-063332ctd:C024292
Drugbromophos-ethyl

ESR1 ESR2

6.11e-063332CID000020965
Drugdihydrobiochanin A

ESR1 ESR2

6.11e-063332CID000439784
Drugrhapontigenin

ESR1 ESR2

6.11e-063332ctd:C431126
DrugEstradiol

ESR1 ESR2

6.11e-063332DB00783
DrugNorgestrel

ESR1 ESR2

6.11e-063332ctd:D009644
Drugbicyclo(3.3.1)nonane

ESR1 ESR2

6.11e-063332CID000136101
Drugcedrol

ESR1 ESR2

6.11e-063332ctd:C078669
Drugraloxifene core

ESR1 ESR2

6.11e-063332CID000445920
Drug2-propylpentanoic acid; Down 200; 1000uM; HL60; HT_HG-U133A

COL4A2 IFNGR2 HGF C8A ESR1

6.98e-061873352669_DN
DrugFlavoxate hydrochloride [3717-88-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A

ATRN COL8A1 ZNF318 ESR1 HHAT

8.55e-061953355427_DN
Drug2-propylpentanoic acid; Down 200; 200uM; HL60; HT_HG-U133A

USP36 COL4A2 HGF C8A ESR1

8.98e-061973352674_DN
DrugLobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A

ERMAP ATRN COL8A1 ESR1 ESR2

9.21e-061983355500_UP
Diseaseprostate carcinoma in situ (implicated_via_orthology)

ESR1 ESR2

1.29e-062342DOID:8634 (implicated_via_orthology)
DiseaseCerebral Astrocytoma

HGF ESR1 ESR2

3.16e-0625343C0750935
DiseaseIntracranial Astrocytoma

HGF ESR1 ESR2

3.16e-0625343C0750936
DiseasePilocytic Astrocytoma

HGF ESR1 ESR2

3.16e-0625343C0334583
DiseaseAstrocytoma

HGF ESR1 ESR2

3.16e-0625343C0004114
DiseaseJuvenile Pilocytic Astrocytoma

HGF ESR1 ESR2

3.16e-0625343C0280783
DiseaseDiffuse Astrocytoma

HGF ESR1 ESR2

3.16e-0625343C0280785
DiseaseGrade I Astrocytoma

HGF ESR1 ESR2

3.16e-0625343C1704230
DiseaseSubependymal Giant Cell Astrocytoma

HGF ESR1 ESR2

3.16e-0625343C0205768
DiseaseMixed oligoastrocytoma

HGF ESR1 ESR2

3.16e-0625343C0547065
DiseaseChildhood Cerebral Astrocytoma

HGF ESR1 ESR2

3.16e-0625343C0338070
DiseaseGemistocytic astrocytoma

HGF ESR1 ESR2

3.57e-0626343C0334581
DiseaseProtoplasmic astrocytoma

HGF ESR1 ESR2

3.57e-0626343C0334580
DiseaseFibrillary Astrocytoma

HGF ESR1 ESR2

3.57e-0626343C0334582
Diseaseperitonitis (implicated_via_orthology)

ESR1 ESR2

3.86e-063342DOID:8283 (implicated_via_orthology)
DiseaseAnaplastic astrocytoma

HGF ESR1 ESR2

4.01e-0627343C0334579
Diseaseprimary ovarian insufficiency (implicated_via_orthology)

USP36 USP17L4 USP17L8

2.05e-0546343DOID:5426 (implicated_via_orthology)
Diseasecongenital heart disease (implicated_via_orthology)

USP36 USP17L4 USP17L8

6.95e-0569343DOID:1682 (implicated_via_orthology)
DiseaseProstatic Intraepithelial Neoplasias

ESR1 ESR2

7.04e-0511342C0282612
DiseaseMyopia

IFNGR2 MFSD2A DYSF HHAT SHISA6

7.51e-05385345HP_0000545
DiseaseHypermetropia

NADSYN1 HHAT SHISA6

2.28e-04103343HP_0000540
Diseasevitiligo (is_implicated_in)

HGF ESR1

2.67e-0421342DOID:12306 (is_implicated_in)
Diseasein situ carcinoma (is_marker_for)

ESR1 ESR2

2.67e-0421342DOID:8719 (is_marker_for)
Diseaseosteoporosis (biomarker_via_orthology)

ESR1 ESR2

2.93e-0422342DOID:11476 (biomarker_via_orthology)
Diseaseinsulin sensitivity measurement

IFNGR2 SHISA6

3.21e-0423342EFO_0004471
Diseasesystemic scleroderma (is_implicated_in)

HGF ESR1

3.50e-0424342DOID:418 (is_implicated_in)
Diseasesugar consumption measurement

COL4A2 USP49 HHAT

3.58e-04120343EFO_0010158
DiseaseSubfertility, Female

ESR1 ESR2

4.78e-0428342C0341869
DiseaseSterility, Postpartum

ESR1 ESR2

4.78e-0428342C0038279
Diseaseosteoarthritis (is_implicated_in)

ESR1 ESR2

4.78e-0428342DOID:8398 (is_implicated_in)
Diseaseanterior thigh muscle fat infiltration measurement

DYSF HHAT

4.78e-0428342EFO_0020936
DiseaseFemale sterility

ESR1 ESR2

4.78e-0428342C0917730
DiseaseFemale infertility

ESR1 ESR2

4.78e-0428342C0021361
Diseaseosteoporosis (is_implicated_in)

ESR1 ESR2

5.87e-0431342DOID:11476 (is_implicated_in)
Diseasemelanoma (is_marker_for)

ESR1 ESR2

6.65e-0433342DOID:1909 (is_marker_for)
Diseaseposterior thigh muscle fat infiltration measurement

DYSF HHAT

7.49e-0435342EFO_0020934

Protein segments in the cluster

PeptideGeneStartEntry
GGYLCSVRVYHYFQW

COX14

26

Q96I36
SYYGGQCETVYNGEW

C8A

171

P07357
GRGTCHYYANKYSFW

COL4A2

1661

P08572
VWYSTYQVGCGIAYC

CRISP2

141

P16562
CYNHDYVQNWESYTG

HYAL2

211

Q12891
VCSDYASGYHYGVWS

ESR2

151

Q92731
CSWDHLYVYDGDSIY

ATRN

181

O75882
AVCNDYASGYHYGVW

ESR1

186

P03372
YASGYHYGVWSCEGC

ESR1

191

P03372
TGYWNVTVYGRKHCY

MYO10

1461

Q9HD67
SCSVYGWGYTGLINY

HGF

611

P14210
CKASGYTFTGYYMHW

IGHV1-2

41

P23083
ITGFVWYCCAYHFYL

PTTG1IP2

111

P0DTF9
LYCYSHVGIAWAQTY

HHAT

476

Q5VTY9
DFPHGQTYWYLLFYC

MFSD2A

151

Q8NA29
ATVWGEADCYVQYYF

C2CD3

1021

Q4AC94
GHQWYWTYEYTDYGG

MT-CO2

101

P00403
YYFAYHVHCKGGNVW

COL8A1

661

P27658
ADTSTAFFCYYVHYW

IFNGR2

166

P38484
AFFCYYVHYWEKGGI

IFNGR2

171

P38484
WCKDHSYVIAGYYQA

EMC8

81

O43402
VFDGCHYYYLPWGNV

DYSF

641

O75923
LTCAVYGGSFSGYYW

IGHV4-34

46

P06331
EYFTTGCHYWEVYVG

ERMAP

286

Q96PL5
ASIHGWTEGNYNYYI

KCNV2

41

Q8TDN2
YETCWGYYDVSGQYD

SHISA6

91

Q6ZSJ9
YIYSGSHDGHINYWD

WDR1

336

O75083
YYINNDTYTGEWFAH

RSPH1

106

Q8WYR4
AGWSCHDGYYFSYVK

USP17L4

326

A6NCW7
CYHYYADWFMSLGVG

TMEM40

176

Q8WWA1
YTAYCYNTEGGFWVH

USP49

616

Q70CQ1
CYFHGRWYADGAVFS

VWCE

501

Q96DN2
AGWSCHNGYYFSYVK

USP17L8

326

P0C7I0
GCQYFSSGKYYWEVD

TRIM22

346

Q8IYM9
AAYEYYDAGNHWCKD

ZNF318

1056

Q5VUA4
HYTAYCYNSEGGFWV

USP44

636

Q9H0E7
GHYYCYVKASNGQWY

USP36

381

Q9P275
FFCIYWGQYATDGIG

TMEM145

221

Q8NBT3
LEICGYGCWDHYYES

NADSYN1

46

Q6IA69