Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP hydrolysis activity	DHX16 SMARCA5 HSP90AB4P DHX40 ABCC11 RNF213 ABCA10 ATP10D MDN1 NAV3 SHOC1 ABCG5 AQR	2.21e-05	441	146	13	GO:0016887
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	GLUD1 GLUD2	5.31e-05	2	146	2	GO:0016639
GeneOntologyMolecularFunction	glutamate dehydrogenase [NAD(P)+] activity	GLUD1 GLUD2	5.31e-05	2	146	2	GO:0004353
GeneOntologyMolecularFunction	glutamate dehydrogenase (NAD+) activity	GLUD1 GLUD2	5.31e-05	2	146	2	GO:0004352
GeneOntologyMolecularFunction	glutamate dehydrogenase (NADP+) activity	GLUD1 GLUD2	5.31e-05	2	146	2	GO:0004354
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	DHX16 SMARCA5 HSP90AB4P DHX40 ABCC11 RNF213 ARHGAP35 ABCA10 ATP10D ARHGAP5 MDN1 RGS6 NAV3 SHOC1 GNG3 ABCG5 AQR	5.32e-05	775	146	17	GO:0017111
GeneOntologyMolecularFunction	pyrophosphatase activity	DHX16 SMARCA5 HSP90AB4P DHX40 ABCC11 RNF213 ARHGAP35 ABCA10 ATP10D ARHGAP5 MDN1 RGS6 NAV3 SHOC1 GNG3 ABCG5 AQR	1.39e-04	839	146	17	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	DHX16 SMARCA5 HSP90AB4P DHX40 ABCC11 RNF213 ARHGAP35 ABCA10 ATP10D ARHGAP5 MDN1 RGS6 NAV3 SHOC1 GNG3 ABCG5 AQR	1.41e-04	840	146	17	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	DHX16 SMARCA5 HSP90AB4P DHX40 ABCC11 RNF213 ARHGAP35 ABCA10 ATP10D ARHGAP5 MDN1 RGS6 NAV3 SHOC1 GNG3 ABCG5 AQR	1.41e-04	840	146	17	GO:0016818
GeneOntologyMolecularFunction	protein-arginine deiminase activity	PADI2 PADI1	5.23e-04	5	146	2	GO:0004668
GeneOntologyMolecularFunction	ATP-dependent activity	DHX16 SMARCA5 HSP90AB4P DHX40 ABCC11 RNF213 ABCA10 ATP10D MDN1 NAV3 SHOC1 ABCG5 AQR	5.85e-04	614	146	13	GO:0140657
GeneOntologyMolecularFunction	L-leucine binding	GLUD1 GLUD2	1.09e-03	7	146	2	GO:0070728
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	DOCK4 WASL RIN3 ARHGAP35 ARHGEF17 KRIT1 ARHGAP5 NF1 RGS6 SYDE2 HERC1	1.28e-03	507	146	11	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	DOCK4 WASL RIN3 ARHGAP35 ARHGEF17 KRIT1 ARHGAP5 NF1 RGS6 SYDE2 HERC1	1.28e-03	507	146	11	GO:0030695
HumanPheno	Spermatocyte maturation arrest	RNF212 TEX15 SHOC1	3.79e-06	5	38	3	HP:0031039
Domain	ELFV_dehydrog_N	GLUD1 GLUD2	5.99e-05	2	145	2	PF02812
Domain	Glu/Leu/Phe/Val_DH_C	GLUD1 GLUD2	5.99e-05	2	145	2	IPR006096
Domain	Glu/Leu/Phe/Val_DH_dimer_dom	GLUD1 GLUD2	5.99e-05	2	145	2	IPR006097
Domain	Glu/Leu/Phe/Val_DH	GLUD1 GLUD2	5.99e-05	2	145	2	IPR006095
Domain	ELFV_dehydrog	GLUD1 GLUD2	5.99e-05	2	145	2	PF00208
Domain	RhoGAP-FF1	ARHGAP35 ARHGAP5	5.99e-05	2	145	2	PF16512
Domain	RhoGAP-FF1	ARHGAP35 ARHGAP5	5.99e-05	2	145	2	IPR032835
Domain	NAD_bind_Glu_DH	GLUD1 GLUD2	5.99e-05	2	145	2	IPR033922
Domain	GLFV_DEHYDROGENASE	GLUD1 GLUD2	5.99e-05	2	145	2	PS00074
Domain	ELFV_dehydrog	GLUD1 GLUD2	5.99e-05	2	145	2	SM00839
Domain	Glu/Leu/Phe/Val_DH_AS	GLUD1 GLUD2	5.99e-05	2	145	2	IPR033524
Domain	ARM-type_fold	MON2 USP34 SMG1 ARMC12 UBR4 TOGARAM1 AP4E1 NF1 MROH1 LTN1 WDFY3	6.96e-05	339	145	11	IPR016024
Domain	GPR137	GPR137C GPR137B	1.79e-04	3	145	2	IPR029723
Domain	G-gamma	RGS6 GNG3 GNG7	2.38e-04	16	145	3	PF00631
Domain	-	RGS6 GNG3 GNG7	2.38e-04	16	145	3	4.10.260.10
Domain	G-protein_gamma-like_dom	RGS6 GNG3 GNG7	2.38e-04	16	145	3	IPR015898
Domain	GGL	RGS6 GNG3 GNG7	2.38e-04	16	145	3	SM00224
Domain	Gprotein-gamma	RGS6 GNG3 GNG7	2.38e-04	16	145	3	IPR001770
Domain	G_PROTEIN_GAMMA	RGS6 GNG3 GNG7	2.38e-04	16	145	3	PS50058
Domain	ARM-like	MON2 SMG1 ARMC12 TOGARAM1 AP4E1 NF1 MROH1 LTN1 WDFY3	2.64e-04	270	145	9	IPR011989
Domain	-	GTF2IRD2B GTF2IRD2	3.56e-04	4	145	2	3.90.1460.10
Domain	GTF2I	GTF2IRD2B GTF2IRD2	3.56e-04	4	145	2	PS51139
Domain	GTF2I	GTF2IRD2B GTF2IRD2	3.56e-04	4	145	2	PF02946
Domain	GTF2I	GTF2IRD2B GTF2IRD2	3.56e-04	4	145	2	IPR004212
Domain	PAD	PADI2 PADI1	5.89e-04	5	145	2	PF03068
Domain	PAD_N	PADI2 PADI1	5.89e-04	5	145	2	PF08526
Domain	PAD_M	PADI2 PADI1	5.89e-04	5	145	2	PF08527
Domain	PAD	PADI2 PADI1	5.89e-04	5	145	2	IPR004303
Domain	PAD_C	PADI2 PADI1	5.89e-04	5	145	2	IPR013530
Domain	Prot_Arg_deaminase_cen_dom	PADI2 PADI1	5.89e-04	5	145	2	IPR013733
Domain	PAD_N	PADI2 PADI1	5.89e-04	5	145	2	IPR013732
Domain	-	DHX16 SMARCA5 DHX40 ABCC11 RNF213 ARHGAP35 ABCA10 NOD2 ARHGAP5 MDN1 NAV3 DLG3 ABCG5 AQR TJP3	7.03e-04	746	145	15	3.40.50.300
Domain	FF_domain	ARHGAP35 ARHGAP5	8.80e-04	6	145	2	IPR002713
Domain	FF	ARHGAP35 ARHGAP5	8.80e-04	6	145	2	PS51676
Domain	FF	ARHGAP35 ARHGAP5	8.80e-04	6	145	2	PF01846
Domain	FF	ARHGAP35 ARHGAP5	8.80e-04	6	145	2	SM00441
Domain	AAA	ABCC11 RNF213 ABCA10 MDN1 NAV3 ABCG5	9.14e-04	144	145	6	SM00382
Domain	AAA+_ATPase	ABCC11 RNF213 ABCA10 MDN1 NAV3 ABCG5	9.14e-04	144	145	6	IPR003593
Domain	GS_dom	ACVR1B BMPR1B	1.23e-03	7	145	2	IPR003605
Domain	GS	ACVR1B BMPR1B	1.23e-03	7	145	2	PS51256
Domain	TGF_beta_GS	ACVR1B BMPR1B	1.23e-03	7	145	2	PF08515
Domain	ZnF_UBR1	UBR4 UBR3	1.23e-03	7	145	2	SM00396
Domain	GS	ACVR1B BMPR1B	1.23e-03	7	145	2	SM00467
Domain	ZF_UBR	UBR4 UBR3	1.23e-03	7	145	2	PS51157
Domain	zf-UBR	UBR4 UBR3	1.23e-03	7	145	2	PF02207
Domain	Znf_UBR	UBR4 UBR3	1.23e-03	7	145	2	IPR003126
Domain	-	MON2 ARMC12 TOGARAM1 AP4E1 NF1 MROH1 WDFY3	1.76e-03	222	145	7	1.25.10.10
Domain	NaH_exchanger	SLC9A4 SLC9A5	2.08e-03	9	145	2	IPR004709
Domain	DnaJ_C	DNAJB1 DNAJB4	2.08e-03	9	145	2	IPR002939
Domain	DnaJ_C	DNAJB1 DNAJB4	2.08e-03	9	145	2	PF01556
Domain	HSP40/DnaJ_pept-bd	DNAJB1 DNAJB4	2.08e-03	9	145	2	IPR008971
Domain	P-loop_NTPase	DHX16 SMARCA5 DHX40 ABCC11 RNF213 ARHGAP35 ABCA10 NOD2 ARHGAP5 MDN1 NAV3 DLG3 ABCG5 AQR TJP3	2.49e-03	848	145	15	IPR027417
Domain	DNA/RNA_helicase_DEAH_CS	DHX16 SMARCA5 DHX40	2.50e-03	35	145	3	IPR002464
Domain	SPAN-X	SPANXN1 SPANXN5	2.59e-03	10	145	2	PF07458
Domain	Amidohydro_1	CAD CRMP1	2.59e-03	10	145	2	PF01979
Domain	Metal-dep_hydrolase_composite	CAD CRMP1	2.59e-03	10	145	2	IPR011059
Domain	Activin_recp	ACVR1B BMPR1B	2.59e-03	10	145	2	PF01064
Domain	Activin_recp	ACVR1B BMPR1B	2.59e-03	10	145	2	IPR000472
Domain	SPAN-X_fam	SPANXN1 SPANXN5	2.59e-03	10	145	2	IPR010007
Domain	Amidohydro-rel	CAD CRMP1	3.14e-03	11	145	2	IPR006680
Domain	Cation/H_exchanger_CPA1	SLC9A4 SLC9A5	3.14e-03	11	145	2	IPR018422
Domain	DEAH_ATP_HELICASE	DHX16 SMARCA5 DHX40	3.17e-03	38	145	3	PS00690
Domain	TGFB_receptor	ACVR1B BMPR1B	3.75e-03	12	145	2	IPR000333
Domain	Rho_GTPase_activation_prot	ARHGAP35 ARHGAP5 NF1 SYDE2	4.91e-03	88	145	4	IPR008936
Domain	Na_H_Exchanger	SLC9A4 SLC9A5	5.12e-03	14	145	2	PF00999
Domain	Cation/H_exchanger	SLC9A4 SLC9A5	5.12e-03	14	145	2	IPR006153
Domain	ABC_tran	ABCC11 ABCA10 ABCG5	6.14e-03	48	145	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCC11 ABCA10 ABCG5	6.14e-03	48	145	3	PS50893
Domain	ABC_TRANSPORTER_1	ABCC11 ABCA10 ABCG5	6.50e-03	49	145	3	PS00211
Domain	ABC_transporter-like	ABCC11 ABCA10 ABCG5	6.88e-03	50	145	3	IPR003439
Domain	DUF1605	DHX16 DHX40	7.54e-03	17	145	2	IPR011709
Domain	OB_NTP_bind	DHX16 DHX40	7.54e-03	17	145	2	PF07717
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CFAP47 CCDC73 VPS13C UBR4 RNF213 OIP5 GPAM ACVR1B ARHGEF17 BIRC6 RYR1 ARHGAP5 PRR35 MDN1 ADO SYDE2	1.49e-07	736	151	16	29676528
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	DHX16 USP34 DNAJB1 SMARCA5 CAD UBR4 ZMYND8 NUP98 DNAJB4 RNF213 SART1 MDN1 SUGP2 ZNF532 POLR1E SUPT5H FANCI AQR	4.73e-07	1014	151	18	32416067
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	DHX16 USP34 SMARCA5 CAD UBR4 NUP98 BIRC6 SART1 NF1 MDN1 SUGP2 SUPT5H FANCI AQR	1.10e-06	653	151	14	22586326
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	UBR4 RNF213 HACE1 LTN1 UBR3 HERC1	3.83e-06	95	151	6	29643511
Pubmed	Isolation and mapping of novel mouse brain cDNA clones containing trinucleotide repeats, and demonstration of novel alleles in recombinant inbred strains.	MDN1 GLUD1 GLUD2 GPR137B	4.02e-06	25	151	4	8858346
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MON2 USP34 RIN3 UBR4 MLXIP ARHGAP35 BIRC6 RYR1 NOD2 MDN1 MROH1 SUGP2 ZNF827 FANCI WDFY3 HERC1 TJP3	6.78e-06	1105	151	17	35748872
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	USP34 VPS13C SEC24A NUP98 RNF213 ACVR1B BIRC6 RUFY3 DMXL1 SART1 AP4E1 SUGP2 SYDE2 DLG3	8.09e-06	777	151	14	35844135
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	SMARCA5 CAD DHX40 TEX15 ARHGEF17 MDN1 PIP HERC1	9.05e-06	234	151	8	36243803
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	HORMAD2 RGSL1 CLEC1A WLS MS4A10 AP4E1 TMTC1 SUGP2 SHOC1 PADI2 GEN1 LIPI PCDH18	1.02e-05	686	151	13	29987050
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RNF213 TOGARAM1 GPAM ARHGAP35 UBN2 BIRC6 LTN1 ELAPOR1 UBR3 PCDH18 TMEM63A	1.12e-05	493	151	11	15368895
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	DOCK4 DNAJB1 WASL SMARCA5 DTNA NUP98 ARHGAP35 ARHGEF17 SPANXN5 ARHGAP5 PPP6C FANCI SYDE2 PIP GLUD1	1.18e-05	916	151	15	32203420
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MON2 DHX16 DOCK4 MLXIP ARHGEF17 MROH1 SUGP2 NAV3 DLG3 AQR	1.25e-05	407	151	10	12693553
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	USP34 WASL UBR4 ZMYND8 RUFY3 CRMP1 KRIT1 ARHGAP5 ZNF532 CIAO3 SUPT5H GLUD1 NAV3 PKNOX1 CCN2 WDFY3 PADI2 GEN1	1.28e-05	1285	151	18	35914814
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	GABRG1 SMG1 SMARCA5 DTNA UBR4 NUP98 PHEX SART1 RAD51AP1 GTF2IRD2B BMPR1B MDN1 CIAO3 GLUD1 GLUD2 GTF2IRD2 DLG3 ALCAM DTHD1	1.69e-05	1442	151	19	35575683
Pubmed	Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn's disease but also ulcerative colitis.	NOD2 IL23R	1.87e-05	2	151	2	17877509
Pubmed	NOD2/CARD15 and IL23R genetic variability in 204 Algerian Crohn's disease.	NOD2 IL23R	1.87e-05	2	151	2	24679666
Pubmed	Glutamate Delta-1 Receptor Regulates Inhibitory Neurotransmission in the Nucleus Accumbens Core and Anxiety-Like Behaviors.	GLUD1 GLUD2	1.87e-05	2	151	2	34173171
Pubmed	Glutamate dehydrogenase is essential to sustain neuronal oxidative energy metabolism during stimulation.	GLUD1 GLUD2	1.87e-05	2	151	2	28621566
Pubmed	GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior.	GLUD1 GLUD2	1.87e-05	2	151	2	32078638
Pubmed	Development of mice with brain-specific deletion of floxed glud1 (glutamate dehydrogenase 1) using cre recombinase driven by the nestin promoter.	GLUD1 GLUD2	1.87e-05	2	151	2	23595828
Pubmed	Common variants in NOD2 and IL23R are not associated with inflammatory bowel disease in Indians.	NOD2 IL23R	1.87e-05	2	151	2	21155887
Pubmed	Polymorphism of interleukin-23 receptor gene but not of NOD2/CARD15 is associated with graft-versus-host disease after hematopoietic stem cell transplantation in children.	NOD2 IL23R	1.87e-05	2	151	2	19896081
Pubmed	Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways.	GLUD1 GLUD2	1.87e-05	2	151	2	21621574
Pubmed	Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia.	GLUD1 GLUD2	1.87e-05	2	151	2	28911206
Pubmed	Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase.	GLUD1 GLUD2	1.87e-05	2	151	2	22875990
Pubmed	Molecular basis of human glutamate dehydrogenase regulation under changing energy demands.	GLUD1 GLUD2	1.87e-05	2	151	2	15578726
Pubmed	Important role of Ser443 in different thermal stability of human glutamate dehydrogenase isozymes.	GLUD1 GLUD2	1.87e-05	2	151	2	15044002
Pubmed	Induction of excitatory and inhibitory presynaptic differentiation by GluD1.	GLUD1 GLUD2	1.87e-05	2	151	2	22138648
Pubmed	Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia.	GLUD1 GLUD2	1.87e-05	2	151	2	34220417
Pubmed	Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues.	GLUD1 GLUD2	1.87e-05	2	151	2	26241911
Pubmed	A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.	NOD2 IL23R	1.87e-05	2	151	2	17068223
Pubmed	Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum.	GLUD1 GLUD2	1.87e-05	2	151	2	21446915
Pubmed	NOD2/CARD15 genotype influences MDP-induced cytokine release and basal IL-12p40 levels in primary isolated peripheral blood monocytes.	NOD2 IL23R	1.87e-05	2	151	2	18383179
Pubmed	GluD1 binds GABA and controls inhibitory plasticity.	GLUD1 GLUD2	1.87e-05	2	151	2	38060673
Pubmed	Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type mice.	GLUD1 GLUD2	1.87e-05	2	151	2	24593767
Pubmed	The p190 RhoGAPs, ARHGAP35, and ARHGAP5 are implicated in GnRH neuronal development: Evidence from patients with idiopathic hypogonadotropic hypogonadism, zebrafish, and in vitro GAP activity assay.	ARHGAP35 ARHGAP5	1.87e-05	2	151	2	36178483
Pubmed	Potentiation of neuronal activity by tonic GluD1 current in brain slices.	GLUD1 GLUD2	1.87e-05	2	151	2	37154294
Pubmed	Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission.	GLUD1 GLUD2	1.87e-05	2	151	2	22924626
Pubmed	Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status.	NOD2 IL23R	1.87e-05	2	151	2	18022867
Pubmed	Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic function.	GLUD1 GLUD2	1.87e-05	2	151	2	11032875
Pubmed	Variants in IL23R-C1orf141 and ADO-ZNF365-EGR2 are associated with susceptibility to Vogt-Koyanagi-Harada disease in Japanese population.	ADO IL23R	1.87e-05	2	151	2	32437414
Pubmed	Synergistic roles for G-protein γ3 and γ7 subtypes in seizure susceptibility as revealed in double knock-out mice.	GNG3 GNG7	1.87e-05	2	151	2	22207761
Pubmed	Insufficient evidence for association of NOD2/CARD15 or other inflammatory bowel disease-associated markers on GVHD incidence or other adverse outcomes in T-replete, unrelated donor transplantation.	NOD2 IL23R	1.87e-05	2	151	2	20177049
Pubmed	Localization of Human Glutamate Dehydrogenases Provides Insights into Their Metabolic Role and Their Involvement in Disease Processes.	GLUD1 GLUD2	1.87e-05	2	151	2	29943084
Pubmed	Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory.	GLUD1 GLUD2	1.87e-05	2	151	2	31898404
Pubmed	Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux.	GLUD1 GLUD2	1.87e-05	2	151	2	15378063
Pubmed	Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions.	GLUD1 GLUD2	1.87e-05	2	151	2	27422263
Pubmed	Critical role of the cysteine 323 residue in the catalytic activity of human glutamate dehydrogenase isozymes.	GLUD1 GLUD2	1.87e-05	2	151	2	15750346
Pubmed	Molecular cloning, structure and expression analysis of a full-length mouse brain glutamate dehydrogenase cDNA.	GLUD1 GLUD2	1.87e-05	2	151	2	1711373
Pubmed	IL23R Arg381Gln is associated with childhood onset inflammatory bowel disease in Scotland.	NOD2 IL23R	1.87e-05	2	151	2	17337463
Pubmed	Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate.	GLUD1 GLUD2	1.87e-05	2	151	2	20529287
Pubmed	IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease.	NOD2 IL23R	1.87e-05	2	151	2	17484863
Pubmed	Determination of glutamate dehydrogenase activity and its kinetics in mouse tissues using metabolic mapping (quantitative enzyme histochemistry).	GLUD1 GLUD2	1.87e-05	2	151	2	25124006
Pubmed	RhoA is down-regulated at cell-cell contacts via p190RhoGAP-B in response to tensional homeostasis.	ARHGAP35 ARHGAP5	1.87e-05	2	151	2	23552690
Pubmed	Unexpected histone H3 tail-clipping activity of glutamate dehydrogenase.	GLUD1 GLUD2	1.87e-05	2	151	2	23673664
Pubmed	Association of NOD2 and IL23R with inflammatory bowel disease in Puerto Rico.	NOD2 IL23R	1.87e-05	2	151	2	25259511
Pubmed	Connective tissue growth factor and its role in lung adenocarcinoma invasion and metastasis.	CRMP1 CCN2	1.87e-05	2	151	2	14996858
Pubmed	Lack of evidence for direct ligand-gated ion channel activity of GluD receptors.	GLUD1 GLUD2	1.87e-05	2	151	2	39052831
Pubmed	Metabolism changes during aging in the hippocampus and striatum of glud1 (glutamate dehydrogenase 1) transgenic mice.	GLUD1 GLUD2	1.87e-05	2	151	2	24442550
Pubmed	The Amplifying Pathway of the β-Cell Contributes to Diet-induced Obesity.	GLUD1 GLUD2	1.87e-05	2	151	2	27137930
Pubmed	GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution.	GLUD1 GLUD2	1.87e-05	2	151	2	26440896
Pubmed	Neuregulin induces CTGF expression in hypertrophic scarring fibroblasts.	NRG1 CCN2	1.87e-05	2	151	2	22350758
Pubmed	Study of structure-function relationships in human glutamate dehydrogenases reveals novel molecular mechanisms for the regulation of the nerve tissue-specific (GLUD2) isoenzyme.	GLUD1 GLUD2	1.87e-05	2	151	2	12742085
Pubmed	Mitochondrial targeting adaptation of the hominoid-specific glutamate dehydrogenase driven by positive Darwinian selection.	GLUD1 GLUD2	1.87e-05	2	151	2	18688271
Pubmed	The complex regulation of human glud1 and glud2 glutamate dehydrogenases and its implications in nerve tissue biology.	GLUD1 GLUD2	1.87e-05	2	151	2	22658952
Pubmed	Increases in anterograde axoplasmic transport in neurons of the hyper-glutamatergic, glutamate dehydrogenase 1 (Glud1) transgenic mouse: Effects of glutamate receptors on transport.	GLUD1 GLUD2	1.87e-05	2	151	2	38124277
Pubmed	Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis.	GLUD1 GLUD2	1.87e-05	2	151	2	19015267
Pubmed	Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum.	GLUD1 GLUD2	1.87e-05	2	151	2	19448744
Pubmed	Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	1.87e-05	2	151	2	15388857
Pubmed	Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme.	GLUD1 GLUD2	1.87e-05	2	151	2	11950837
Pubmed	The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype.	NOD2 IL23R	1.87e-05	2	151	2	20428899
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DHX16 SMARCA5 CAD DIS3L2 DHX40 UBR4 BIRC6 SART1 NF1 MDN1 PPP6C SUGP2 POLR1E FANCI PIP LTN1 WDFY3 AQR	2.53e-05	1353	151	18	29467282
Pubmed	A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.	DHX16 PRPSAP2 DNAJB1 DHX40 NUP98 DNAJB4 FANCI LTN1 EDRF1	3.20e-05	363	151	9	25036637
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	DHX16 DNAJB1 SMARCA5 ZMYND8 SART1 SUGP2 SUPT5H PIP	3.54e-05	283	151	8	30585729
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	MON2 PRPSAP2 DOCK4 CAD DTNA UBR4 ARHGAP35 BIRC6 RUFY3 NF1 SUGP2 GLUD1 GLUD2 NAV3 UBR3 DLG3	3.86e-05	1139	151	16	36417873
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	MON2 DNAJB1 CAD DTNA SEC24A NUP98 RNF213 BIRC6 ARHGAP5 PPP6C SUPT5H FANCI LTN1 UBR3 HERC1	5.58e-05	1049	151	15	27880917
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	MON2 DOCK4 USP34 CAD DTNA DHX40 UBN2 RUFY3 ADO SUPT5H ZMYM6	5.60e-05	588	151	11	38580884
Pubmed	CARD15 and IL23R influences Crohn's disease susceptibility but not disease phenotype in a Brazilian population.	NOD2 IL23R	5.60e-05	3	151	2	18200510
Pubmed	NOD2, IL23R and ATG16L1 polymorphisms in Lithuanian patients with inflammatory bowel disease.	NOD2 IL23R	5.60e-05	3	151	2	20082483
Pubmed	The structure of apo human glutamate dehydrogenase details subunit communication and allostery.	GLUD1 GLUD2	5.60e-05	3	151	2	12054821
Pubmed	Toll-like receptor 9, NOD2 and IL23R gene polymorphisms influenced outcome in AML patients transplanted from HLA-identical sibling donors.	NOD2 IL23R	5.60e-05	3	151	2	20622911
Pubmed	Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons.	GLUD1 GLUD2	5.60e-05	3	151	2	31704028
Pubmed	Hypoxia-Associated Factor (HAF) Mediates Neurofibromin Ubiquitination and Degradation Leading to Ras-ERK Pathway Activation in Hypoxia.	SART1 NF1	5.60e-05	3	151	2	30705246
Pubmed	Peptidylarginine deiminases and deimination in biology and pathology: relevance to skin homeostasis.	PADI2 PADI1	5.60e-05	3	151	2	16973334
Pubmed	NOD2/CARD15, ATG16L1 and IL23R gene polymorphisms and childhood-onset of Crohn's disease.	NOD2 IL23R	5.60e-05	3	151	2	20380008
Pubmed	Association of IL23R and ATG16L1 with susceptibility of Crohn's disease in Chinese population.	NOD2 IL23R	5.60e-05	3	151	2	25048429
Pubmed	The CTLA4 variants may interact with the IL23R- and NOD2-conferred risk in development of Crohn's disease.	NOD2 IL23R	5.60e-05	3	151	2	20537165
Pubmed	Neuregulin-1 overexpression and Trp53 haploinsufficiency cooperatively promote de novo malignant peripheral nerve sheath tumor pathogenesis.	NRG1 NF1	5.60e-05	3	151	2	24232507
Pubmed	Confirmation of three inflammatory bowel disease susceptibility loci in a Chinese cohort.	NOD2 IL23R	5.60e-05	3	151	2	22426692
Pubmed	ATG16L1 Ala197Thr is not associated with susceptibility to Crohn's disease or with phenotype in an Italian population.	NOD2 IL23R	5.60e-05	3	151	2	18166373
Pubmed	Postsynaptic δ1 glutamate receptor assembles and maintains hippocampal synapses via Cbln2 and neurexin.	GLUD1 GLUD2	5.60e-05	3	151	2	29784783
Pubmed	Genetic variations of interleukin-23R (1143A>G) and BPI (A645G), but not of NOD2, are associated with acute graft-versus-host disease after allogeneic transplantation.	NOD2 IL23R	5.60e-05	3	151	2	20541026
Pubmed	Role of ATG16L, NOD2 and IL23R in Crohn's disease pathogenesis.	NOD2 IL23R	5.60e-05	3	151	2	22346247
Pubmed	Replication and meta-analysis of 13,000 cases defines the risk for interleukin-23 receptor and autophagy-related 16-like 1 variants in Crohn's disease.	NOD2 IL23R	5.60e-05	3	151	2	20485703
Pubmed	Selective tissue distribution of G protein gamma subunits, including a new form of the gamma subunits identified by cDNA cloning.	GNG3 GNG7	5.60e-05	3	151	2	1385432
Pubmed	Association of IL23R p.381Gln and ATG16L1 p.197Ala with Crohn disease in the Czech population.	NOD2 IL23R	5.60e-05	3	151	2	19590455
Pubmed	Glutamine-Elicited Secretion of Glucagon-Like Peptide 1 Is Governed by an Activated Glutamate Dehydrogenase.	GLUD1 GLUD2	5.60e-05	3	151	2	29229616
Pubmed	Liver Glutamate Dehydrogenase Controls Whole-Body Energy Partitioning Through Amino Acid-Derived Gluconeogenesis and Ammonia Homeostasis.	GLUD1 GLUD2	5.60e-05	3	151	2	30002133
Pubmed	Glutamate delta-1 receptor regulates cocaine-induced plasticity in the nucleus accumbens.	GLUD1 GLUD2	5.60e-05	3	151	2	30315226
Pubmed	IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease.	NOD2 IL23R	5.60e-05	3	151	2	17894849
Interaction	PLEKHA2 interactions	PRPSAP2 DTNA TNIP2 ARHGAP35 SNTG1 DLG3 EDRF1	4.78e-06	94	143	7	int:PLEKHA2
GeneFamily	Peptidyl arginine deiminases	PADI2 PADI1	2.54e-04	5	92	2	677
GeneFamily	Ubiquitin protein ligase E3 component n-recognins	UBR4 UBR3	5.29e-04	7	92	2	785
GeneFamily	Type 1 receptor serine/threonine kinases	ACVR1B BMPR1B	5.29e-04	7	92	2	345
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	DOCK4 USP34 NRG1 SMARCA5 GALNT1 SEC24A ZMYND8 NUP98 TOGARAM1 ARHGAP35 KRIT1 SLC35A3 MDN1 LTN1 NAV3 CCN2 ALCAM WDFY3 AQR	3.85e-07	856	148	19	M4500
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	MON2 USP34 SMG1 VPS13C RNF213 BIRC6 NF1 HERC1	2.81e-07	188	152	8	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 RYR1 ARHGAP5 HACE1 LTN1 KCNN3 PADI2	2.14e-06	172	152	7	7fb31ccbcd0204c3612986a6bc20d57ed6825e9c
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 RYR1 ARHGAP5 HACE1 LTN1 KCNN3 PADI2	2.14e-06	172	152	7	2a4614b3d25e8c6b095e6992d8ca35371dcdb5e1
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	MLXIP ARSD CIAO3 UBR3 ALCAM AQR TMEM63A	3.35e-06	184	152	7	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MON2 USP34 SMG1 RNF213 SUGP2 HERC1 DTHD1	5.61e-06	199	152	7	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	MON2 USP34 BIRC6 NF1 UBR3 WDFY3 HERC1	5.61e-06	199	152	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Sepsis-URO-Lymphocyte-T/NK-CD4+_Tem\|URO / Disease, condition lineage and cell class	CCDC168 GTF2IRD2B ELAPOR1 LY9 IL23R TMEM63A TJP3	5.79e-06	200	152	7	8b7bfe6411de9528603481f6e5612cbbb8471cf6
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CFAP47 GABRG1 DTNA GPAM BMPR1B GLUD1 KCNN3	5.79e-06	200	152	7	07d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCell	Control-Endothelial-Epi-like\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ACKR4 RAD51AP1 MROH1 LONRF3 ZMYM6 TJP3	1.67e-05	157	152	6	4d02c50d5d1b892ea241e98724386d8a5a156a46
ToppCell	Control-Endothelial-Epi-like-Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ACKR4 RAD51AP1 MROH1 LONRF3 ZMYM6 TJP3	1.67e-05	157	152	6	2c369660c752c0fb3bd798a561d3359e2f9aa983
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GALT1 KLK7 CCDC73 CCN2 PCDH18 ABCG5	2.80e-05	172	152	6	073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCell	Severe-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RIN3 TNIP2 RYR1 PHEX PIP GPR137B	3.39e-05	178	152	6	b7374a97c51239782bed658381a02cb1b3d9bf66
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	OIP5 RAD51AP1 GPR137C FANCI ELAPOR1 GEN1	4.46e-05	187	152	6	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	MON2 VPS13C RNF213 BIRC6 ALCAM EDRF1	5.02e-05	191	152	6	9454f642c3621370fa23640b631301346b300950
ToppCell	Severe-B_intermediate-10\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RIN3 VPS13C RYR1 PHEX PIP GPR137B	6.13e-05	198	152	6	dfae26c3513a82bb7cb8dadbfcea2a1f420b1bab
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CLEC1A ACKR4 NAV3 KCNN3 CCN2 PCDH18	6.30e-05	199	152	6	eeb7d370d4dfacf705306c72ccc4919ddefacff1
ToppCell	Macroglial-Astrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	B3GALT1 GABRG1 DTNA BMPR1B GLUD1 KCNN3	6.48e-05	200	152	6	941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCell	Macroglial-Astrocytes-SLC14A1---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	B3GALT1 GABRG1 GPAM BMPR1B GLUD1 KCNN3	6.48e-05	200	152	6	d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCell	Macroglial-Astrocytes-SLC14A1----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	B3GALT1 GABRG1 GPAM BMPR1B GLUD1 KCNN3	6.48e-05	200	152	6	f861509b54185d89931db64da1b9d81986cc7938
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GABRG1 DTNA GPAM BMPR1B GLUD1 KCNN3	6.48e-05	200	152	6	d0812817ef99608994193787a62d39adeb2070ca
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 SMG1 SMARCA5 VPS13C RNF213 BIRC6	6.48e-05	200	152	6	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Transverse-Dendritic_cell-cycling_DCs\|Transverse / Region, Cell class and subclass	DOCK4 NRG1 OIP5 WLS RAD51AP1 FANCI	6.48e-05	200	152	6	f588d8889f351c797963616a3575fa43efd46b9a
ToppCell	Macroglial-Astrocytes-SLC14A1\|Macroglial / cells hierarchy compared to all cells using T-Statistic	B3GALT1 GABRG1 GPAM BMPR1B GLUD1 KCNN3	6.48e-05	200	152	6	16f468217427921fa18c6d078ffa990eb019b257
ToppCell	Macroglial-Astrocytes-SLC14A1--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	B3GALT1 GABRG1 GPAM BMPR1B GLUD1 KCNN3	6.48e-05	200	152	6	0442894c39eec69850c090957a5dc7bcecd21e04
ToppCell	Transverse-(5)_Dendritic_cell-(52)_cycling_DCs\|Transverse / shred on region, Cell_type, and subtype	DOCK4 NRG1 OIP5 WLS RAD51AP1 FANCI	6.48e-05	200	152	6	51e643d48b5e97a0e117b578a6ea7d429c6cdd1e
ToppCell	Macroglial-Astrocytes-SLC14A1-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	B3GALT1 GABRG1 GPAM BMPR1B GLUD1 KCNN3	6.48e-05	200	152	6	01819446deeab9054f5cfe889d53bb49d137dbc0
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GABRG1 DTNA GPAM BMPR1B GLUD1 KCNN3	6.48e-05	200	152	6	cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	ARMC12 CNPY4 ARSD SYDE2 GNG7 TMEM63A	6.48e-05	200	152	6	be83f442179ba4217d12f0458059586ff3130991
Drug	Palmatine chloride [3486-67-7]; Up 200; 10.4uM; PC3; HT_HG-U133A	DTNA ZMYND8 ACVR1B ARHGAP35 THAP9 PHEX BMPR1B ARSD GNG7 PADI2	8.40e-07	199	150	10	6612_UP
Drug	ureidoglycine	CIAO3 GLUD1 GLUD2	1.12e-06	4	150	3	CID000439649
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA	DNAJB1 DTNA ZMYND8 DNAJB4 ACVR1B ARHGAP35 RUFY3 PKNOX1 EDRF1	2.50e-06	175	150	9	1006_UP
Drug	l-413	CAD GLUD1 GLUD2	2.78e-06	5	150	3	CID000012475
Drug	2 pc	NRG1 NF1 GLUD1 GLUD2	5.15e-06	18	150	4	CID000440046
Drug	Methylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; PC3; HT_HG-U133A	B3GALT1 NRG1 ACVR1B RUFY3 PHEX NF1 ARSD SUGP2 EDRF1	6.31e-06	196	150	9	3994_UP
Drug	Trichlorfon [52-68-6]; Up 200; 15.6uM; MCF7; HT_HG-U133A	DOCK4 FMO4 ACVR1B ARHGEF17 CRMP1 NF1 PKNOX1 GNG7 PADI2	6.57e-06	197	150	9	1675_UP
Drug	Meropenem [96036-03-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A	USP34 CNPY4 DNAJB4 ARHGAP35 AP4E1 NF1 DLG3 TMEM63A TJP3	6.57e-06	197	150	9	7180_UP
Drug	Sulfamethoxypyridazine [80-35-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A	ZMYND8 ACVR1B MLXIP ARHGEF17 CUZD1 PKNOX1 AQR PADI1 TMEM63A	6.84e-06	198	150	9	3609_DN
Drug	PHA-00745360 [351320-33-7]; Down 200; 10uM; MCF7; HT_HG-U133A	DTNA RUFY3 AP4E1 SLC9A5 NF1 CUZD1 GNG7 EDRF1 TMEM63A	7.42e-06	200	150	9	3907_DN
Drug	Quercetine dihydrate [6151-25-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A	MON2 USP34 NUP98 KRIT1 DMXL1 LTN1 WDFY3 ZMYM6	2.64e-05	180	150	8	2859_DN
Drug	Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A	USP34 ZMYND8 ARHGAP35 RUFY3 SUGP2 WDFY3 EDRF1 TMEM63A	4.04e-05	191	150	8	3605_DN
Drug	Resveratrol [501-36-0]; Down 200; 17.6uM; MCF7; HT_HG-U133A	NUP98 ARHGAP35 RUFY3 SLC35A3 NF1 SUGP2 PKNOX1 DLG3	4.19e-05	192	150	8	5509_DN
Drug	Resveratrol [501-36-0]; Down 200; 17.6uM; MCF7; HT_HG-U133A	DTNA NUP98 KRIT1 NF1 CUZD1 PKNOX1 AQR TMEM63A	4.19e-05	192	150	8	2865_DN
Drug	phenyltriethoxysilane	GLUD1 GLUD2	4.31e-05	2	150	2	CID000013075
Drug	G-3SH	GLUD1 GLUD2	4.31e-05	2	150	2	CID000174237
Drug	iodoacetyldiethylstilbestrol	GLUD1 GLUD2	4.31e-05	2	150	2	CID006455327
Drug	methylmercuric bromide	GLUD1 GLUD2	4.31e-05	2	150	2	CID000068175
Drug	5-methylisophthalate	GLUD1 GLUD2	4.31e-05	2	150	2	CID000068137
Drug	x 1 s	GLUD1 GLUD2	4.31e-05	2	150	2	CID000409694
Drug	Calycanthine [595-05-1]; Up 200; 11.6uM; MCF7; HT_HG-U133A	DOCK4 TEX15 ACVR1B RYR1 NF1 CUZD1 LONRF3 PADI1	4.34e-05	193	150	8	2764_UP
Drug	Simvastatin [79902-63-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A	CNPY4 MLXIP THAP9 CRMP1 NOD2 SLC9A5 NF1 ELAPOR1	4.34e-05	193	150	8	3340_UP
Drug	(-)-Quinpirole hydrochloride [85760-74-3]; Down 200; 15.6uM; MCF7; HT_HG-U133A	TRAPPC11 DTNA DNAJB4 RUFY3 NF1 PKNOX1 EDRF1 TMEM63A	4.51e-05	194	150	8	7481_DN
Drug	Tetrahydroxy-1,4-quinone monohydrate [319-89-1]; Down 200; 21uM; MCF7; HT_HG-U133A	DTNA ZMYND8 NUP98 ARHGAP35 NF1 WDFY3 GNG3 PADI1	4.51e-05	194	150	8	4159_DN
Drug	yohimbine; Up 200; 22.9uM; MCF7; HT_HG-U133A_EA	TRAPPC11 SMARCA5 DTNA VPS13C ARHGAP35 ARHGAP5 NF1 SUGP2	4.51e-05	194	150	8	1119_UP
Drug	ICI182,780; Down 200; 1uM; PC3; HT_HG-U133A	RIN3 RUFY3 SLC9A5 NF1 POLR1E PKNOX1 GNG7 TMEM63A	4.67e-05	195	150	8	7539_DN
Drug	Palmatine chloride [3486-67-7]; Up 200; 10.4uM; MCF7; HT_HG-U133A	ACVR1B ARHGAP35 RYR1 CRMP1 NF1 SNTG1 WDFY3 GNG7	4.67e-05	195	150	8	2795_UP
Drug	Luteolin [491-70-3]; Down 200; 14uM; MCF7; HT_HG-U133A	USP34 FMO4 DTNA ZMYND8 NUP98 ARHGAP35 NF1 DLG3	4.67e-05	195	150	8	5004_DN
Drug	PNU-0230031 [267429-39-0]; Up 200; 1uM; PC3; HT_HG-U133A	RIN3 DTNA ACVR1B ARHGAP35 ARHGEF17 THAP9 PHEX LY9	4.85e-05	196	150	8	4291_UP
Drug	Diflorasone Diacetate [33564-31-7]; Up 200; 8uM; MCF7; HT_HG-U133A	MON2 USP34 ACVR1B ELAPOR1 ALCAM WDFY3 GNG7 TMEM63A	4.85e-05	196	150	8	2798_UP
Drug	Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A	ZMYND8 ARHGAP35 ARHGEF17 ATP10D AP4E1 SLC9A5 PADI1 TMEM63A	4.85e-05	196	150	8	5276_DN
Drug	genistein; Down 200; 10uM; PC3; HT_HG-U133A	KLK7 ZMYND8 ACVR1B PHEX BMPR1B NF1 GNG7 TMEM63A	5.02e-05	197	150	8	4459_DN
Drug	Flumequine [42835-25-6]; Up 200; 15.4uM; MCF7; HT_HG-U133A	ZMYND8 ACVR1B RUFY3 NF1 SNTG1 GNG7 EDRF1 TMEM63A	5.02e-05	197	150	8	5529_UP
Drug	Dipyrone [5907-38-0]; Down 200; 12uM; PC3; HT_HG-U133A	USP34 DNAJB4 ARHGAP35 RUFY3 NF1 PKNOX1 GNG7 PADI1	5.21e-05	198	150	8	3754_DN
Drug	chlorpromazine hydrochloride; Down 200; 1uM; HL60; HT_HG-U133A	DTNA DNAJB4 TOGARAM1 ACVR1B NF1 LY9 EDRF1 AQR	5.21e-05	198	150	8	1158_DN
Drug	Sotalol hydrochloride [959-24-0]; Up 200; 13uM; PC3; HT_HG-U133A	RIN3 DTNA REN MLXIP PHEX NF1 PIP GNG3	5.21e-05	198	150	8	4079_UP
Drug	Fluvoxamine maleate [61718-82-9]; Up 200; 9.2uM; PC3; HT_HG-U133A	NRG1 KLK7 RIN3 CLEC1A TEX15 PHEX RGS6 TJP3	5.21e-05	198	150	8	3995_UP
Drug	Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; PC3; HT_HG-U133A	DTNA RUFY3 NF1 SUGP2 PKNOX1 DLG3 WDFY3 EDRF1	5.21e-05	198	150	8	3756_DN
Drug	Suprofen [40828-46-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A	RIN3 CNPY4 ARHGEF17 RUFY3 NF1 ALCAM LY9 TMEM63A	5.21e-05	198	150	8	3343_UP
Drug	Liothyronine [6893-02-3]; Up 200; 6.2uM; PC3; HT_HG-U133A	TEX15 ACVR1B CRMP1 NF1 ARSD PIP PADI2 ABCG5	5.39e-05	199	150	8	6602_UP
Drug	Tetrahydrozoline hydrochloride [522-48-5]; Down 200; 16.8uM; MCF7; HT_HG-U133A	RIN3 DTNA WLS ALCAM WDFY3 ZMYM6 AQR TMEM63A	5.39e-05	199	150	8	6069_DN
Drug	Benzonatate [104-31-4]; Up 200; 6.6uM; MCF7; HT_HG-U133A	DTNA RUFY3 AP4E1 NF1 CUZD1 PKNOX1 WDFY3 TMEM63A	5.39e-05	199	150	8	1679_UP
Drug	Testosterone propionate [57-85-2]; Up 200; 11.6uM; HL60; HT_HG-U133A	DTNA ACVR1B POLR1E LY9 GNG3 GNG7 PADI2 TMEM63A	5.39e-05	199	150	8	1295_UP
Drug	Norcyclobenzaprine [303-50-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A	USP34 DTNA NUP98 WLS PHEX ALCAM WDFY3 PADI2	5.39e-05	199	150	8	2830_DN
Drug	Trimethadione [127-48-0]; Up 200; 28uM; PC3; HT_HG-U133A	NRG1 KLK7 DTNA TEX15 ARHGEF17 PHEX NF1 TMEM63A	5.59e-05	200	150	8	4086_UP
Drug	Sparteine (-) [90-39-1]; Up 200; 17uM; HL60; HT_HG-U133A	UBR4 ZMYND8 MLXIP AP4E1 CIAO3 CUZD1 PADI2 PADI1	5.59e-05	200	150	8	2134_UP
Drug	Coralyne chloride hydrate [38989-38-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A	ZMYND8 NUP98 RUFY3 SLC35A3 SUGP2 PKNOX1 PADI1 TMEM63A	5.59e-05	200	150	8	2652_DN
Drug	TNP-GTP	ARHGAP35 GLUD1 GLUD2	7.64e-05	13	150	3	CID000126171
Drug	lenthionine	GLUD1 GLUD2	1.29e-04	3	150	2	CID000067521
Drug	maltose tetrapalmitate	RYR1 PIP	1.29e-04	3	150	2	CID003035236
Drug	mildiomycin	GLUD1 GLUD2	1.29e-04	3	150	2	CID000125665
Drug	methoxyethylmercury	GLUD1 GLUD2	1.29e-04	3	150	2	CID000115155
Drug	4-methylumbelliferyl laurate	GLUD1 GLUD2	1.29e-04	3	150	2	CID000600674
Drug	methylmercuric iodide	GLUD1 GLUD2	1.29e-04	3	150	2	CID000067347
Drug	MDL-899	REN RYR1	1.29e-04	3	150	2	CID000071143
Drug	Withaferin A [5119-48-2]; Up 200; 1uM; MCF7; HT_HG-U133A	DNAJB1 DNAJB4 RUFY3 CRMP1 NOD2 KCNN3 CCN2	1.95e-04	180	150	7	4376_UP
Drug	Azaguanine-8 [134-58-7]; Down 200; 26.2uM; PC3; HT_HG-U133A	DNAJB1 SEC24A ZMYND8 NUP98 RUFY3 KRIT1 SUGP2	2.02e-04	181	150	7	1791_DN
Drug	17-AAG; Up 200; 1uM; HL60; HT_HG-U133A	DNAJB1 CNPY4 DNAJB4 ACVR1B NOD2 NF1 TMEM63A	2.16e-04	183	150	7	6166_UP
Drug	NH4Cl	TNIP2 REN BIRC6 SLC9A5 GLUD1 GLUD2 SLC4A9	2.24e-04	184	150	7	CID000025517
Drug	17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A	DNAJB1 ZMYND8 DNAJB4 ARHGAP35 NF1 GNG7 EDRF1	2.24e-04	184	150	7	5210_UP
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A	DNAJB1 RIN3 ZMYND8 DNAJB4 ARHGAP35 GNG7 EDRF1	2.31e-04	185	150	7	6986_UP
Drug	Securinine [5610-40-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A	DNAJB1 DNAJB4 ARHGEF17 RYR1 CUZD1 PKNOX1 EDRF1	2.39e-04	186	150	7	6831_UP
Drug	Loperamide hydrochloride [34552-83-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A	WASL ARHGEF17 RYR1 PIP ZMYM6 PADI1 TMEM63A	2.39e-04	186	150	7	1533_UP
Drug	Ethaverine hydrochloride [985-13-7]; Up 200; 9.2uM; HL60; HT_HG-U133A	DOCK4 NRG1 ARHGAP35 RYR1 RUFY3 ARSD ELAPOR1	2.47e-04	187	150	7	3037_UP
Drug	methyl benzoquate	GLUD1 GLUD2	2.56e-04	4	150	2	CID000026383
Drug	pentenoic acid	GLUD1 GLUD2	2.56e-04	4	150	2	CID000012299
Drug	alpha-ketoglutaramate	GLUD1 GLUD2	2.56e-04	4	150	2	CID000000048
Drug	Ivin	GLUD1 GLUD2	2.56e-04	4	150	2	CID000014083
Drug	8-BDB-TADP	GLUD1 GLUD2	2.56e-04	4	150	2	CID000130791
Drug	cadina-3,9-diene	GLUD1 GLUD2	2.56e-04	4	150	2	CID000010657
Drug	AC1L9CUQ	GLUD1 GLUD2	2.56e-04	4	150	2	CID000442451
Drug	luxabendazole	GLUD1 GLUD2	2.56e-04	4	150	2	CID000072019
Drug	N-butylmaleimide	GLUD1 GLUD2	2.56e-04	4	150	2	CID000239780
Drug	alpha-methylglutamate	GLUD1 GLUD2	2.56e-04	4	150	2	CID000095440
Drug	2b E2	GLUD1 GLUD2	2.56e-04	4	150	2	CID005327076
Drug	radicicol; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	DNAJB1 ZMYND8 DNAJB4 ACVR1B ARHGAP35 PHEX PKNOX1	2.63e-04	189	150	7	836_UP
Drug	geldanamycin; Up 200; 1uM; MCF7; HG-U133A	DNAJB1 SEC24A DNAJB4 CRMP1 PHEX ARHGAP5 PADI1	2.63e-04	189	150	7	611_UP
Drug	radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A	DNAJB1 DTNA UBR4 DNAJB4 ARHGAP5 LONRF3 GNG7	2.72e-04	190	150	7	5579_UP
Drug	radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A	USP34 DNAJB1 DNAJB4 TEX15 NF1 GNG7 TMEM63A	2.72e-04	190	150	7	6979_UP
Drug	Proglumide [6620-60-6]; Up 200; 12uM; MCF7; HT_HG-U133A	KLK7 ACVR1B ARHGEF17 NF1 ARSD CUZD1 EDRF1	2.81e-04	191	150	7	3861_UP
Drug	15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A	WASL MLXIP CRMP1 RGS6 ELAPOR1 GNG7 EDRF1	2.90e-04	192	150	7	7489_UP
Drug	Nitrendipine [39562-70-4]; Up 200; 11uM; HL60; HT_HG-U133A	MON2 DOCK4 ACVR1B DLG3 CCN2 PADI2 EDRF1	2.90e-04	192	150	7	3087_UP
Drug	Podophyllotoxin [518-28-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A	WASL RYR1 NOD2 NF1 ARSD LY9 GNG7	2.99e-04	193	150	7	6103_UP
Drug	Graveoline [485-61-0]; Down 200; 14.4uM; MCF7; HT_HG-U133A	ARHGEF17 RUFY3 NF1 SUGP2 CUZD1 ALCAM WDFY3	2.99e-04	193	150	7	3614_DN
Drug	Thioguanosine [85-31-4]; Up 200; 12.6uM; PC3; HT_HG-U133A	KLK7 RIN3 DTNA TEX15 ACVR1B AP4E1 PADI1	2.99e-04	193	150	7	6643_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A	MON2 DTNA ACVR1B RUFY3 NOD2 NF1 EDRF1	2.99e-04	193	150	7	2721_DN
Drug	Oxyphenbutazone [129-20-4]; Up 200; 12.4uM; PC3; HT_HG-U133A	MON2 MLXIP THAP9 AP4E1 BMPR1B ARSD PADI2	3.09e-04	194	150	7	4506_UP
Drug	Norgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A	WASL DTNA ZMYND8 ACVR1B PHEX NF1 EDRF1	3.09e-04	194	150	7	3606_DN
Drug	CP-319743 [172078-87-4]; Down 200; 10uM; PC3; HT_HG-U133A	RUFY3 SLC9A5 NF1 POLR1E CCN2 GNG7 TJP3	3.09e-04	194	150	7	7537_DN
Drug	Dichlorphenamide [120-97-8]; Down 200; 13.2uM; MCF7; HT_HG-U133A	USP34 DTNA ZMYND8 AP4E1 NF1 WDFY3 TMEM63A	3.09e-04	194	150	7	3366_DN
Drug	Galanthamine hydrobromide [1953-04-4]; Down 200; 10.8uM; MCF7; HT_HG-U133A	USP34 FMO4 DTNA ACVR1B RUFY3 EDRF1 ZMYM6	3.09e-04	194	150	7	2787_DN
Drug	0317956-0000 [391210-11-0]; Down 200; 10uM; PC3; HT_HG-U133A	RIN3 FMO4 SLC9A5 ARSD PIP GNG7 TMEM63A	3.09e-04	194	150	7	3774_DN
Drug	Loxapine succinate [27833-64-3]; Up 200; 9uM; MCF7; HT_HG-U133A	DTNA NUP98 DNAJB4 ANKRA2 PKNOX1 ALCAM PADI1	3.09e-04	194	150	7	5293_UP
Drug	Skimmianine [83-95-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A	ZMYND8 ARHGEF17 RUFY3 RGS6 SUGP2 CUZD1 WDFY3	3.09e-04	194	150	7	6242_UP
Drug	Solanine alpha [20562-02-1]; Down 200; 4.6uM; MCF7; HT_HG-U133A	USP34 DTNA ZMYND8 ACVR1B RAD51AP1 WDFY3 EDRF1	3.18e-04	195	150	7	2808_DN
Drug	Ifenprodil tartrate [23210-58-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A	DTNA DNAJB4 RUFY3 NF1 SUGP2 DLG3 PADI2	3.18e-04	195	150	7	7404_DN
Drug	Chicago sky blue 6B [2610-05-1]; Up 200; 4uM; MCF7; HT_HG-U133A	DTNA MLXIP NF1 FANCI WDFY3 GNG7 EDRF1	3.18e-04	195	150	7	3266_UP
Drug	Mephenytoin [50-12-4]; Down 200; 18.4uM; MCF7; HT_HG-U133A	NF1 CUZD1 ALCAM WDFY3 ZMYM6 TMEM63A TJP3	3.18e-04	195	150	7	3580_DN
Drug	Triflusal [322-79-2]; Down 200; 16.2uM; MCF7; HT_HG-U133A	ACVR1B RUFY3 NF1 SUGP2 PKNOX1 ZMYM6 TMEM63A	3.18e-04	195	150	7	7451_DN
Drug	Fluspirilen [1841-19-6]; Down 200; 8.4uM; PC3; HT_HG-U133A	RIN3 FMO4 ARHGAP35 NF1 PIP PKNOX1 TJP3	3.18e-04	195	150	7	6662_DN
Disease	fructose measurement	NRG1 UBR4 BMPR1B	3.21e-05	13	145	3	EFO_0010477
Disease	fascioliasis (biomarker_via_orthology)	GLUD1 GLUD2	7.17e-05	3	145	2	DOID:885 (biomarker_via_orthology)
Disease	autosomal dominant limb-girdle muscular dystrophy type 1 (implicated_via_orthology)	DNAJB1 DNAJB4	1.43e-04	4	145	2	DOID:0110305 (implicated_via_orthology)
Disease	congenital myopathy 21 (implicated_via_orthology)	DNAJB1 DNAJB4	1.43e-04	4	145	2	DOID:0081353 (implicated_via_orthology)
Disease	nephrolithiasis (implicated_via_orthology)	SLC9A4 SLC9A5	2.38e-04	5	145	2	DOID:585 (implicated_via_orthology)
Disease	childhood absence epilepsy (biomarker_via_orthology)	GLUD1 GLUD2	3.55e-04	6	145	2	DOID:1825 (biomarker_via_orthology)
Disease	acetoacetate measurement	GPAM MLXIP	6.59e-04	8	145	2	EFO_0010111
Disease	cysteine measurement	FMO4 NAV3	8.44e-04	9	145	2	EFO_0021000
Disease	rheumatoid arthritis, Crohn's disease	HORMAD2 NOD2 IL23R	8.64e-04	38	145	3	EFO_0000384, EFO_0000685
Disease	cerebral cavernous malformation (implicated_via_orthology)	RNF213 KRIT1	1.28e-03	11	145	2	DOID:0060669 (implicated_via_orthology)
Disease	interleukin 18 receptor 1 measurement	SLC9A4 IL23R	2.41e-03	15	145	2	EFO_0008178
Disease	hepatic encephalopathy (biomarker_via_orthology)	GLUD1 GLUD2	2.41e-03	15	145	2	DOID:13413 (biomarker_via_orthology)
Disease	sleep apnea measurement	WASL SLC9A4 SNTG1 ZMYM6	2.62e-03	116	145	4	EFO_0007817
Disease	cutaneous psoriasis measurement, psoriasis	ADO RGS6	2.75e-03	16	145	2	EFO_0000676, EFO_0007773
Disease	Moyamoya Disease	RNF213 NF1	3.11e-03	17	145	2	C0026654
Disease	ovulation	FANCI FAM227A	3.88e-03	19	145	2	GO_0030728
Disease	leprosy, Crohn's disease	NOD2 SLC9A4	4.30e-03	20	145	2	EFO_0000384, EFO_0001054
Disease	ulcerative colitis, Crohn's disease	NOD2 IL23R	4.30e-03	20	145	2	EFO_0000384, EFO_0000729
Disease	Fetal Growth Retardation	REN GLUD1	4.30e-03	20	145	2	C0015934
Disease	alkaline phosphatase measurement	USP34 RIN3 DNAJB4 GPAM CRMP1 PHEX RAD51AP1 NF1 RGS6 ZNF827 FAM227A NRSN1	4.44e-03	1015	145	12	EFO_0004533

Protein segments in the cluster

Peptide	Gene	Start	Entry
YTDVISETLCSMKKR	FAM227A	466	F5H4B4
LTSFFFAMALKCVKT	SLC4A9	636	Q96Q91
TLLSTMKYVAKVVAE	ADGRF3	526	Q8IZF5
LEKTASLMLKEAVSY	ARSD	271	P51689
INKYKMVETITCLSR	CFAP61	1091	Q8NHU2
SVEVTYLKKQCETML	CNPY4	146	Q8N129
LLAKMKTCVDTYTNR	BIRC6	4436	Q9NR09
VSICTSELSMKVYVD	CATSPER3	91	Q86XQ3
LICVSTIMVSTQYEK	ABCA10	1056	Q8WWZ4
LKVLYGTVRISCMDK	ADO	121	Q96SZ5
MCLSKDKTLQDLVYD	ACVR1B	171	P36896
MASKVSCLYVLTVVC	B3GALT1	1	Q9Y5Z6
YLLVKEAKIIAMTCT	AQR	1026	O60306
LACSKGYTDIVKMLL	ANKRA2	221	Q9H9E1
KMILASEKYSCSEEI	DHX16	826	O60231
DKYSLARKEVLTNMC	DIS3L2	651	Q8IYB7
LDAKSMLKLAYSSVS	BMPR1B	296	O00238
SLEEIYSGCTKKMKI	DNAJB1	171	P25685
KTSKYMPRASVCNVL	DMXL1	241	Q9Y485
SLECKQDEYAKSMIL	ARMC12	76	Q5T9G4
TLCIAKKVMSDTEYA	ATP10D	841	Q9P241
KLYKLLMNDSVSSET	AP4E1	536	Q9UPM8
PAKVAVLTTVYCMAK	C17orf113	126	A0A1B0GUU1
SAVPCTKMALDDKLY	RAD51AP1	81	Q96B01
FLEDMSYLTLKANCK	PADI1	321	Q9ULC6
CLKMSKVAESLIAYT	RGS6	276	P49758
KASLADSGEYMCKVI	NRG1	101	Q02297
LLKCMIFEYAESVTS	PCDH18	671	Q9HCL0
MCETLTYISKEQLLS	LTN1	1346	O94822
VLGKIMCKITSALYT	ACKR4	106	Q9NPB9
TAASVIDTASKYKML	ARHGEF17	1336	Q96PE2
GSCVDTLLKDLCKMY	FANCI	1156	Q9NVI1
TLLKDLCKMYTTLTA	FANCI	1161	Q9NVI1
HQCITAMKEYESKSL	NUP98	186	P52948
SYCSKLVKVMLDLQS	MDN1	1241	Q9NU22
MKSLKYCDVDSVSAR	EDRF1	1001	Q3B7T1
SLSEYVSCMKEAQKS	HSP90AB4P	376	Q58FF6
SLKMVKKLFATSISC	HORMAD2	31	Q8N7B1
YSKLVMNATLKDCDL	ELAPOR1	941	Q6UXG2
AISLVCYICKITKMS	GPR137C	216	Q8N3F9
MKSLSALLGCSKYAE	HERC1	2516	Q15751
ITMVTKYLITAAAKA	IDO2	361	Q6ZQW0
KDSMFSLALKCLISL	KCNN3	311	Q9UGI6
TKMDLSYSKTAKQCL	NAV3	656	Q8IVL0
AGCLLMSVFVKSYSK	NRSN1	131	Q8IZ57
MTRVYKSLVTNVCKE	FMO4	51	P31512
KSLVTNVCKEMSCYS	FMO4	56	P31512
KKCMSKLLEYSADVN	HACE1	111	Q8IYU2
SKTYLKMLCLMTNLI	MS4A10	116	Q96PG2
VTSEVLTCIKLIKMY	ABCC11	341	Q96J66
CTKVYKDLLENSMLC	KLK7	176	P49862
KSKMLALEKADTCIY	KRIT1	216	O00522
RIKVSKAAADLMTYC	GNG3	31	P63215
VSTLKPCAKDAYMLF	MON2	206	Q7Z3U7
KLSCSDVSLYKMLTY	OR2T34	191	Q8NGX1
KLSCSDVSLYKTLMY	OR2T3	191	Q8NH03
KFLLLMASTSACYKL	PADI2	486	Q9Y2J8
EKSMATYILKDFNAC	TMEM63A	356	O94886
RKKAMLTCTYLVSVE	MROH1	841	Q8NDA8
LKLMVYNSKSDSCRE	GORASP1	161	Q9BQQ3
KMSCTNTRVYEKVLL	OR9G4	201	Q8NGQ1
MKYSLCKDSLSLLLD	PRR35	56	P0CG20
LTKLFECMTLAYSGK	MLXIP	126	Q9HAP2
MRKFAYCKVVLATSL	GALNT1	1	Q10472
VSLEEIYSGCTKRMK	DNAJB4	166	Q9UDY4
TKDDLILKVYMCNTE	DOCK4	316	Q8N1I0
IKVSKAASDLMSYCE	GNG7	26	O60262
KVSYVTAMDLFVSVC	GABRG1	326	Q8N1C3
IKFELSGCTSMKTYR	CCN2	266	P29279
VKALASLMTYKCAVV	GLUD1	161	P00367
ASDLIKSKVTCQYKM	CCDC73	221	Q6ZRK6
TTIEKVSCEMRYKAT	IL23R	246	Q5VWK5
RVQMIESAYKKSAIC	ABCG5	321	Q9H222
ASLKNTSDMVYLKVA	DLG3	296	Q92796
MTTSSIICDISKKYI	DTHD1	136	Q6ZMT9
LMCSVKGAEKSVLYS	LY9	176	Q9HBG7
KISVFAVKMALATLC	DTNA	126	Q9Y4J8
CYTMSSIKSKLGLDR	GEN1	181	Q17RS7
IMVYACKTSCAKSII	PRPSAP2	91	O60256
GYCVSSIKKLTEVKM	CCDC168	2856	Q8NDH2
KFLRSMSSVYLQCKV	CUZD1	486	Q86UP6
TCLICKQSMSVSKEY	GTF2IRD2	446	Q86UP8
TCLICKQSMSVSKEY	GTF2IRD2B	446	Q6EKJ0
SKETAIKYMTDGCLL	DHX40	141	Q8IX18
CYLMSKEIPFSVKKT	ZMYND8	321	Q9ULU4
KEMITSLFCKLAALV	RYR1	3036	P21817
YKCSLIDKKSMIAST	ALCAM	311	Q13740
SEAMKSKLESCVALY	CFAP47	2966	Q6ZTR5
SKLESCVALYMIEKS	CFAP47	2971	Q6ZTR5
VKALASLMTYKCAVV	GLUD2	161	P49448
YITKVMSKSAADIIA	CRMP1	251	Q14194
SIIYTLCNKEMKAAL	OR10G6	306	Q8NH81
ILLKTCKLIYDSMAL	RIN3	761	Q8TB24
SDKMVCYLLKTKAIV	OIP5	166	O43482
CYLLKTKAIVNASEM	OIP5	171	O43482
NLISDSMKAKITAYV	POLR1E	326	Q9GZS1
AVSLSICLYKISKMS	GPR137B	206	O60478
LKLVASYHEVNKMTC	SYDE2	961	Q5VT97
DKITQAAMETIYLCK	RUFY3	16	Q7L099
LTDITKMSFEELCYK	RGSL1	571	A5PLK6
QCSTCTYKIQSLMLK	LIPI	411	Q6XZB0
YIACLKTKMNSETLL	PKNOX1	146	P55347
SVYEIMCKILKDSDL	SNTG1	336	Q9NSN8
MTPSTDFYKKLALDC	SEC24A	666	O95486
YSSKKLCTLAIHAMD	REN	356	P00797
AESATYCLVKNAVKM	GPAM	771	Q9HCL2
MQDCYSKIVDKLSSA	SMG1	1926	Q96Q15
LAITACAVTMKKYVE	SLC9A4	326	Q6AI14
LSDFIMLRNKYKTCT	SHOC1	521	Q5VXU9
TTVKYTMKTLASCAE	SLC9A5	326	Q14940
MCSVYLKDSEKVVSI	SUPT5H	1011	O00267
ASKLQSAEKLMYICT	ARHGAP5	121	Q13017
KKMKTSEYSTVLAFC	SPANXN1	41	Q5VSR9
ELKECMVVKTYLISS	PIP	61	P12273
ISYLCILLTVFKMKS	OR5K4	216	A6NMS3
AATKLASAEKLMYFC	ARHGAP35	121	Q9NRY4
SKVAFYCKTTRELML	ATRAID	46	Q6UW56
VTVMPCYDKKLEASR	CIAO3	241	Q9H6Q4
CKYFCLSENSTMLKI	CLEC1A	161	Q8NC01
SKTAKYLAADALELM	TNIP2	356	Q8NFZ5
FMSIDSLCKKYSRET	RNF212	66	Q495C1
VNKYTDLDSELKIMC	RNF213	1311	Q63HN8
PKIIYKCSMCDTVFT	ZNF532	901	Q9HCE3
CSYLLSRKDIMDSLK	UGT3A1	121	Q6NUS8
CSSSLIKTSDKPLMY	UBN2	966	Q6ZU65
TATYECRVKKTTMAT	VSIG8	121	P0DPA2
SMCETKLLSLKKEVY	ZNF383	81	Q8NA42
LTTALKCSYLMAQLK	TRAPPC11	496	Q7Z392
YHCSIIAMKTLLKFT	WDFY3	476	Q8IZQ1
TLVLMYTCDKTVFKN	TMTC1	126	Q8IUR5
AATCKKYMAKLRTTV	NOD2	216	Q9HC29
EMKQFACTLYLCSSK	THAP9	211	Q9H5L6
YCTKVFDMLTVAALI	PPP6C	141	O00743
KKMKTSEYSTVLVLC	SPANXN5	41	Q5MJ07
ACNAYELSVKMKTLS	SUGP2	446	Q8IX01
KSSIELKHLCLEYMT	NF1	1936	P21359
KILYSSCMNEKAIEK	PHEX	136	P78562
DKLYVCASVEFLMTV	VPS13C	2046	Q709C8
KSLPSAVYCIEDKMA	SART1	666	O43290
CEAYLKAMLSTGFKI	CAD	1296	P27708
ESLKTKMSELRLYCD	PLEKHA3	111	Q9HB20
AASELLMKLSAESYK	ZNF827	651	Q17R98
SAFAIQILKTCTKMA	TJP3	71	O95049
VVTIYTKSISTKCSM	ZMYM6	181	O95789
VTVLLYMMESCLIKS	UBR3	471	Q6ZT12
IMACILLVYKDSKCS	SLC35A3	51	Q9Y2D2
CVYAIKRSMKTFTEL	WEE2	236	P0C1S8
FSFMTYCLISKTEKL	USP34	2756	Q70CQ2
KKCVTMSSAVVQLYA	WASL	36	O00401
CLSDLFTYLKKSMDQ	TOGARAM1	1321	Q9Y4F4
TAVSYMSVKCVDARK	WLS	41	Q5T9L3
MLCEEFVTSYKALKS	TEX15	701	Q9BXT5
DVCVTSYEMLIKEKS	SMARCA5	281	O60264
TKAFMAVCIETAKRY	UBR4	4306	Q5T4S7
LLKELQMKDSASYLC	TRAV1-2	91	A0A0B4J238
CLASRKYSKNVIMEE	LONRF3	511	Q496Y0