Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	fatty acid ligase activity	ACSL1 ACSL6 AACS	3.92e-05	26	51	3	GO:0015645
GeneOntologyMolecularFunction	CoA-ligase activity	ACSL1 ACSL6 AACS	4.40e-05	27	51	3	GO:0016405
GeneOntologyMolecularFunction	acid-thiol ligase activity	ACSL1 ACSL6 AACS	6.71e-05	31	51	3	GO:0016878
GeneOntologyMolecularFunction	ligase activity, forming carbon-sulfur bonds	ACSL1 ACSL6 AACS	1.56e-04	41	51	3	GO:0016877
GeneOntologyMolecularFunction	thiamine pyrophosphate binding	HACL1 TKTL1	1.77e-04	8	51	2	GO:0030976
GeneOntologyMolecularFunction	quaternary ammonium group binding	ABCA1 HACL1 TKTL1	2.21e-04	46	51	3	GO:0050997
GeneOntologyMolecularFunction	arachidonate-CoA ligase activity	ACSL1 ACSL6	3.47e-04	11	51	2	GO:0047676
GeneOntologyMolecularFunction	long-chain fatty acid-CoA ligase activity	ACSL1 ACSL6	6.57e-04	15	51	2	GO:0004467
GeneOntologyMolecularFunction	endopeptidase activity	PAPPA2 PAPPA SPPL2B CTSH USP20 USP33	7.64e-04	430	51	6	GO:0004175
GeneOntologyMolecularFunction	ligase activity	ACSL1 ACSL6 TTLL11 AACS	1.01e-03	174	51	4	GO:0016874
GeneOntologyMolecularFunction	peptidase activity	PAPPA2 PAPPA MINDY4 SPPL2B CTSH USP20 USP33	1.30e-03	654	51	7	GO:0008233
GeneOntologyMolecularFunction	cysteine-type endopeptidase activity	CTSH USP20 USP33	1.38e-03	86	51	3	GO:0004197
GeneOntologyMolecularFunction	cysteine-type peptidase activity	MINDY4 CTSH USP20 USP33	1.45e-03	192	51	4	GO:0008234
GeneOntologyMolecularFunction	cysteine-type deubiquitinase activity	MINDY4 USP20 USP33	3.09e-03	114	51	3	GO:0004843
GeneOntologyBiologicalProcess	positive regulation of long-chain fatty acid import across plasma membrane	ACSL1 ACSL6	1.87e-05	3	52	2	GO:0010747
GeneOntologyBiologicalProcess	positive regulation of long-chain fatty acid import into cell	ACSL1 ACSL6	3.73e-05	4	52	2	GO:0140214
GeneOntologyBiologicalProcess	response to oleic acid	ACSL1 AACS	6.20e-05	5	52	2	GO:0034201
GeneOntologyBiologicalProcess	protein K48-linked deubiquitination	MINDY4 USP20 USP33	6.46e-05	31	52	3	GO:0071108
GeneOntologyBiologicalProcess	regulation of long-chain fatty acid import across plasma membrane	ACSL1 ACSL6	1.30e-04	7	52	2	GO:0010746
Domain	Peptidase_M43	PAPPA2 PAPPA	7.60e-06	2	52	2	IPR008754
Domain	Peptidase_M43	PAPPA2 PAPPA	7.60e-06	2	52	2	PF05572
Domain	Myxo_disulph_rpt	PAPPA2 PAPPA	2.28e-05	3	52	2	IPR011936
Domain	LamGL	PAPPA2 PAPPA	4.55e-05	4	52	2	SM00560
Domain	LamG-like	PAPPA2 PAPPA	4.55e-05	4	52	2	IPR006558
Domain	AMP-binding_CS	ACSL1 ACSL6 AACS	5.06e-05	26	52	3	IPR020845
Domain	AMP_BINDING	ACSL1 ACSL6 AACS	6.35e-05	28	52	3	PS00455
Domain	AMP-binding	ACSL1 ACSL6 AACS	7.84e-05	30	52	3	PF00501
Domain	AMP-dep_Synth/Lig	ACSL1 ACSL6 AACS	7.84e-05	30	52	3	IPR000873
Domain	DUSP	USP20 USP33	1.13e-04	6	52	2	SM00695
Domain	DUSP	USP20 USP33	1.13e-04	6	52	2	PF06337
Domain	-	USP20 USP33	1.58e-04	7	52	2	3.30.2230.10
Domain	DUSP	USP20 USP33	1.58e-04	7	52	2	PS51283
Domain	Notch_dom	PAPPA2 PAPPA	1.58e-04	7	52	2	IPR000800
Domain	Notch	PAPPA2 PAPPA	1.58e-04	7	52	2	PF00066
Domain	Pept_C19_DUSP	USP20 USP33	1.58e-04	7	52	2	IPR006615
Domain	NL	PAPPA2 PAPPA	1.58e-04	7	52	2	SM00004
Domain	ZnF_UBP	USP20 USP33	4.11e-04	11	52	2	SM00290
Domain	THDP-binding	HACL1 TKTL1	5.82e-04	13	52	2	IPR029061
Domain	-	HACL1 TKTL1	5.82e-04	13	52	2	3.40.50.970
Domain	Znf_UBP	USP20 USP33	6.77e-04	14	52	2	IPR001607
Domain	zf-UBP	USP20 USP33	6.77e-04	14	52	2	PF02148
Domain	ZF_UBP	USP20 USP33	6.77e-04	14	52	2	PS50271
Domain	Ig_E-set	FLNA KCNJ9 PLXNA1	3.04e-03	104	52	3	IPR014756
Domain	PSI	ATRNL1 PLXNA1	3.57e-03	32	52	2	PF01437
Domain	Plexin_repeat	ATRNL1 PLXNA1	3.57e-03	32	52	2	IPR002165
Domain	Znf-RING_LisH	TRIM46 TRIM56	4.03e-03	34	52	2	IPR027370
Domain	zf-RING_UBOX	TRIM46 TRIM56	4.03e-03	34	52	2	PF13445
Domain	-	TRIM56 PON2	5.27e-03	39	52	2	2.120.10.30
Domain	PSI	ATRNL1 PLXNA1	6.67e-03	44	52	2	IPR016201
Domain	PSI	ATRNL1 PLXNA1	7.28e-03	46	52	2	SM00423
Domain	6-blade_b-propeller_TolB-like	TRIM56 PON2	7.28e-03	46	52	2	IPR011042
Domain	-	TRIM46 KMT2D TRIM56 USP20 USP33	8.07e-03	449	52	5	3.30.40.10
Domain	Znf_RING/FYVE/PHD	TRIM46 KMT2D TRIM56 USP20 USP33	8.83e-03	459	52	5	IPR013083
Domain	Sushi	PAPPA2 PAPPA	9.22e-03	52	52	2	PF00084
Domain	CCP	PAPPA2 PAPPA	9.92e-03	54	52	2	SM00032
Domain	SUSHI	PAPPA2 PAPPA	1.06e-02	56	52	2	PS50923
Pubmed	Identification and molecular characterization of acyl-CoA synthetase in human erythrocytes and erythroid precursors.	ACSL1 ACSL6	2.19e-06	2	52	2	10548543
Pubmed	Pregnancy-associated plasma protein-A2 (PAPP-A2): tissue expression and biological consequences of gene knockout in mice.	PAPPA2 PAPPA	2.19e-06	2	52	2	21586553
Pubmed	Pregnancy associated plasma protein-A as a prognostic biomarker of all-cause mortality and cardiovascular events in patients presenting with chest pain: a systematic review.	PAPPA2 PAPPA	2.19e-06	2	52	2	29144175
Pubmed	Multiple erythroid isoforms of human long-chain acyl-CoA synthetases are produced by switch of the fatty acid gate domains.	ACSL1 ACSL6	2.19e-06	2	52	2	16834775
Pubmed	Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin.	PAPPA2 PAPPA	2.19e-06	2	52	2	11513734
Pubmed	Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins.	USP20 USP33	2.19e-06	2	52	2	33792613
Pubmed	A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2.	FANCD2 EDIL3	6.57e-06	3	52	2	31219578
Pubmed	Placental expression of PAPPA, PAPPA-2 and PLAC-1 in pregnacies is associated with FGR.	PAPPA2 PAPPA	6.57e-06	3	52	2	29532882
Pubmed	Altered placental expression of PAPPA2 does not affect birth weight in mice.	PAPPA2 PAPPA	6.57e-06	3	52	2	20642865
Pubmed	Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation.	USP20 USP33	6.57e-06	3	52	2	12865408
Pubmed	Identification of a deubiquitinating enzyme subfamily as substrates of the von Hippel-Lindau tumor suppressor.	USP20 USP33	6.57e-06	3	52	2	12056827
Pubmed	Increased levels of pregnancy-associated plasma protein-A2 in the serum of pre-eclamptic patients.	PAPPA2 PAPPA	6.57e-06	3	52	2	18805800
Pubmed	Follow-up association studies of chromosome region 9q and nonsyndromic cleft lip/palate.	TTLL11 PAPPA GABBR2	1.24e-05	30	52	3	20583170
Pubmed	Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling.	USP20 USP33	1.31e-05	4	52	2	21525354
Pubmed	Acyl-CoA synthetase 1 is required for oleate and linoleate mediated inhibition of cholesterol efflux through ATP-binding cassette transporter A1 in macrophages.	ACSL1 ABCA1	1.31e-05	4	52	2	22020260
Pubmed	A Role for the GIRK3 Subunit in Methamphetamine-Induced Attenuation of GABAB Receptor-Activated GIRK Currents in VTA Dopamine Neurons.	KCNJ9 GABBR2	1.31e-05	4	52	2	26985023
Pubmed	Characterization of placental cholesterol transport: ABCA1 is a potential target for in utero therapy of Smith-Lemli-Opitz syndrome.	ABCA1 DHCR7	1.31e-05	4	52	2	18775956
Pubmed	The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization.	USP20 USP33	1.31e-05	4	52	2	19424180
Pubmed	Linkage relationships of peptidase-7, Pep-7, in the mouse.	VPS33A FGF5	1.31e-05	4	52	2	6626149
Pubmed	Identification of novel candidate genes in heterotaxy syndrome patients with congenital heart diseases by whole exome sequencing.	FLNA KMT2D	1.31e-05	4	52	2	32738303
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	PAPPA2 FLNA ABCA1 NHS ITGA7 USP33	1.68e-05	363	52	6	14691545
Pubmed	Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family.	ACSL1 ACSL6	2.19e-05	5	52	2	15292367
Pubmed	Identification of acyl-CoA synthetases involved in the mammalian sphingosine 1-phosphate metabolic pathway.	ACSL1 ACSL6	2.19e-05	5	52	2	24269233
Pubmed	Presynaptic PRRT2 Deficiency Causes Cerebellar Dysfunction and Paroxysmal Kinesigenic Dyskinesia.	SLC17A7 EDIL3	2.19e-05	5	52	2	32891704
Pubmed	T(In1;5)44H, a complex mouse chromosomal rearrangement with a phenotypic effect.	VPS33A FGF5	3.28e-05	6	52	2	8449042
Pubmed	USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110.	USP20 USP33	3.28e-05	6	52	2	23486064
Pubmed	MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors.	USP20 USP33	4.58e-05	7	52	2	23166351
Pubmed	TTLL1 and TTLL4 polyglutamylases are required for the neurodegenerative phenotypes in pcd mice.	TTLL11 EDIL3	4.58e-05	7	52	2	35404950
Pubmed	Ontogeny of mRNA expression and activity of long-chain acyl-CoA synthetase (ACSL) isoforms in Mus musculus heart.	ACSL1 ACSL6	4.58e-05	7	52	2	17197235
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	VPS33A MINDY4 USP20 USP33	7.08e-05	147	52	4	29576527
Pubmed	Casz1 is required for cardiomyocyte G1-to-S phase progression during mammalian cardiac development.	FLNA EDIL3	7.84e-05	9	52	2	25953344
Pubmed	Genetic determinants of plasma HDL-cholesterol levels in familial hypercholesterolemia.	ABCA1 PON2	7.84e-05	9	52	2	16030523
Pubmed	Two new cataract loci, Ccw and To3, and further mapping of the Npp and Opj cataracts in the mouse.	VPS33A FGF5	1.20e-04	11	52	2	8812411
Pubmed	MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner.	KMT2D EDIL3	1.20e-04	11	52	2	37012455
Pubmed	Abnormal nonshivering thermogenesis in mice with inherited defects of fatty acid oxidation.	PTPN13 FGF5	1.20e-04	11	52	2	9802886
Pubmed	The genes of the lysosomal cysteine proteinases cathepsin B, H, L, and S map to different mouse chromosomes.	FLNA CTSH	1.43e-04	12	52	2	9096102
Pubmed	Mouse rump-white mutation associated with an inversion of chromosome 5.	VPS33A FGF5	1.43e-04	12	52	2	8043948
Pubmed	Functional assembly of accessory optic system circuitry critical for compensatory eye movements.	EDIL3 PLXNA1	1.69e-04	13	52	2	25959730
Pubmed	Nucleolar protein trafficking in response to HIV-1 Tat: rewiring the nucleolus.	FLNA PSAT1 USP20	2.13e-04	77	52	3	23166591
Pubmed	The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells.	FLNA PTPN13	2.60e-04	16	52	2	18824598
Pubmed	Maternal and fetal variation in genes of cholesterol metabolism is associated with preterm delivery.	ABCA1 DHCR7	2.60e-04	16	52	2	17855807
Pubmed	Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast.	FGF5 EDIL3	2.60e-04	16	52	2	25480920
Pubmed	A cluster of cholinergic premotor interneurons modulates mouse locomotor activity.	SLC17A7 PAPPA	2.94e-04	17	52	2	20005822
Pubmed	No interaction between alcohol consumption and HDL-related genes on HDL cholesterol levels.	ABCA1 PON2	3.69e-04	19	52	2	20430392
Pubmed	IgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses.	SLC17A7 ITGA7	4.09e-04	20	52	2	22687584
Pubmed	Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function.	SLC17A7 PLXNA1	4.52e-04	21	52	2	21835343
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	ELAPOR2 PSAT1 OAF TTLL11 TRIM56 HACL1 USP20 USP33	4.81e-04	1242	52	8	30973865
Pubmed	Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.	ACSL1 ABCA1 DHCR7 AACS	5.38e-04	250	52	4	18660489
Pubmed	BMP signalling inhibits premature neural differentiation in the mouse embryo.	FGF5 EDIL3	5.93e-04	24	52	2	17699604
Pubmed	Whole-genome sequencing reveals host factors underlying critical COVID-19.	TRIM46 ACSL6	6.43e-04	25	52	2	35255492
Pubmed	Dystroglycan Maintains Inner Limiting Membrane Integrity to Coordinate Retinal Development.	SLC17A7 EDIL3	6.43e-04	25	52	2	28760865
Pubmed	Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins.	KCNJ9 GABBR2	6.43e-04	25	52	2	17185339
Pubmed	Reconstruction of phrenic neuron identity in embryonic stem cell-derived motor neurons.	PAPPA EDIL3	7.51e-04	27	52	2	24496616
Pubmed	Biosynthesis of triacylglycerols.	ACSL1 ACSL6	8.08e-04	28	52	2	8944226
Pubmed	Determination of genetic predisposition to patent ductus arteriosus in preterm infants.	ABCA1 DHCR7 GABBR2	9.65e-04	129	52	3	19336370
Pubmed	Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells.	ABCA1 DHCR7	9.92e-04	31	52	2	19796621
Pubmed	OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase.	USP20 USP33	1.06e-03	32	52	2	33669244
Pubmed	Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin.	USP20 USP33	1.12e-03	33	52	2	30323974
Pubmed	MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons.	PAPPA2 PAPPA	1.26e-03	35	52	2	22407321
Pubmed	A microarray of ubiquitylated proteins for profiling deubiquitylase activity reveals the critical roles of both chain and substrate.	USP20 USP33	1.34e-03	36	52	2	22626734
Cytoband	9q33.2	TTLL11 PAPPA	9.08e-04	39	52	2	9q33.2
Cytoband	Ensembl 112 genes in cytogenetic band chr12q24	ZNF26 ZNF268 VPS33A AACS	1.26e-03	415	52	4	chr12q24
Cytoband	12q24.33	ZNF26 ZNF268	1.37e-03	48	52	2	12q24.33
GeneFamily	Pappalysins\|Sushi domain containing	PAPPA2 PAPPA	3.23e-06	2	33	2	897
GeneFamily	Acyl-CoA synthetase family	ACSL1 ACSL6 AACS	1.40e-05	26	33	3	40
GeneFamily	Ubiquitin specific peptidases	USP20 USP33	4.68e-03	56	33	2	366
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	PAPPA2 PAPPA	4.84e-03	57	33	2	1179
ToppCell	Globus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pappa2_(Mural.Rgs5Acta2.Pappa2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	FANCD2 MKKS PAPPA2 P2RX1 NMNAT3	6.50e-07	141	52	5	a32947b13e888850c979a54c137512e4b96d2f36
ToppCell	Globus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pappa2_(Mural.Rgs5Acta2.Pappa2)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	FANCD2 MKKS PAPPA2 P2RX1 NMNAT3	6.50e-07	141	52	5	2cb651d63466fdcce011d1dd8de409ef439d03e7
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ELAPOR2 PTPN13 PON2 EDIL3 CTSH	2.89e-06	191	52	5	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	(7)_Epithelial-B_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ELAPOR2 PSAT1 PTPN13 DHCR7 CTSH	3.28e-06	196	52	5	345d4cc062b43bca9d506fbf23363469a9ba496f
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	ELAPOR2 PSAT1 PTPN13 DHCR7 CTSH	3.36e-06	197	52	5	f3ca63c7902d7530a29a85eb54f69b303031d150
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	ELAPOR2 PSAT1 PTPN13 DHCR7 CTSH	3.36e-06	197	52	5	f98720cab066579fdac3ba24fb6fe4c5759dae4e
ToppCell	343B-Epithelial_cells\|343B / Donor, Lineage, Cell class and subclass (all cells)	ELAPOR2 PSAT1 PTPN13 DHCR7 CTSH	3.45e-06	198	52	5	0756a5d01572343abce77e7584b816c2c2e9d9c7
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast-mesenchymal_C\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MYLK3 TTLL11 LRRTM2 ACY1	1.22e-05	121	52	4	176de42c088988fe1a7838f96add26ee8a30e543
ToppCell	Tracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF836 ZNF26 PTPN13 NHS	2.16e-05	140	52	4	0e1e9281de87df178ac41ed6b697b4fa09be2749
ToppCell	pdx-Tumor_cells-T9\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	FLNA KMT2D PLCD4 ZNFX1	2.42e-05	144	52	4	0b94d978262a826c9254145aa98c6c30240243f9
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL24 ATRNL1 ITGA7 EDIL3	3.31e-05	156	52	4	6365b69ede98bc866e996bc52736b00401aacf6f
ToppCell	Posterior_cortex\|World / BrainAtlas - Mouse McCarroll V32	MYLK3 KCNJ9 SLC17A7 FGF5	3.56e-05	159	52	4	18e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FANCD2 SLC17A7 FGF5 ITGA7	3.83e-05	162	52	4	58da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ACSL1 ELAPOR2 PSAT1 CTSH	4.02e-05	164	52	4	b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ACSL1 ELAPOR2 PSAT1 CTSH	4.02e-05	164	52	4	3aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSL1 DHCR7 AACS HACL1	4.12e-05	165	52	4	d449a568664a81d9b5538e8f409301448a32ac37
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM46 OAF TTLL11 NMNAT3	5.06e-05	174	52	4	9eab43885496b8586f8ec5b4bcb1fd5b209218e5
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA1 PTPN13 PAPPA EDIL3	5.06e-05	174	52	4	f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA P2RX1 ITGA7 EDIL3	5.18e-05	175	52	4	316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA P2RX1 ITGA7 EDIL3	5.18e-05	175	52	4	a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCell	primary_visual_cortex-Non-neuronal\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	OAF PON2 PLCD4 CTSH	5.29e-05	176	52	4	2c92f3f55d668cfe80051b5128160a6dc3aec4e8
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTLL11 PLCD4 ITGA7 PLXNA1	5.41e-05	177	52	4	7c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTLL11 PLCD4 ITGA7 PLXNA1	5.41e-05	177	52	4	e7b1f3092e6b8d0d580f82648035f5ad12be6961
ToppCell	COVID-19-kidney-vSMC/Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	IL24 P2RX1 NHS EDIL3	5.65e-05	179	52	4	111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	FLNA NHS ITGA7 EDIL3	5.77e-05	180	52	4	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN13 NHS PAPPA EDIL3	6.03e-05	182	52	4	812ff2a50a510b18d865e89465dba1754a08ef61
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 FLNA P2RX1 ITGA7	6.03e-05	182	52	4	ffe500d78a89dc6b4d05bab1664e7f30c94fb8d9
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 FLNA P2RX1 ITGA7	6.29e-05	184	52	4	94748f63947db79a6b4540e3090a63689fdd9452
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 FLNA P2RX1 ITGA7	6.29e-05	184	52	4	819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSL6 PTPN13 OAF PLCD4	6.56e-05	186	52	4	ac7a84b11b4550c4ac01eab370dc8ab88e4fb72b
ToppCell	Differ-KC\|World / shred by cell class for mouse tongue	ACSL1 PSAT1 DHCR7 AACS	6.69e-05	187	52	4	08f70e5103c6dd96f439f0cceda878963d26850d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA P2RX1 ITGA7 EDIL3	6.98e-05	189	52	4	7fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FLNA OAF ATRNL1 NHS	6.98e-05	189	52	4	f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA P2RX1 ITGA7 EDIL3	6.98e-05	189	52	4	06b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCell	(7)_Epithelial-D_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ELAPOR2 PSAT1 DHCR7 PON2	7.12e-05	190	52	4	832d6d3ad14665e50623afe1b8586ccae1a97de5
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA1 OAF NHS PAPPA	7.12e-05	190	52	4	0fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCell	COVID-19-kidney-vSMC/Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	FLNA P2RX1 ITGA7 EDIL3	7.27e-05	191	52	4	fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCell	wk_20-22-Epithelial-Distal_epithelial_progenitor\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PSAT1 PTPN13 PON2 CTSH	7.41e-05	192	52	4	fa2420d6117d4800f60ef6a24bcf8bf54593cd1f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA P2RX1 ITGA7 EDIL3	7.41e-05	192	52	4	b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell	wk_20-22-Epithelial-Distal_epithelial_progenitor-epi-tip_late\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PSAT1 PTPN13 PON2 CTSH	7.41e-05	192	52	4	87b60014202633a4f6d19b09a5dd9276c2edecfb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA P2RX1 ITGA7 EDIL3	7.41e-05	192	52	4	bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ELAPOR2 PTPN13 PON2 CTSH	7.41e-05	192	52	4	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNA P2RX1 ITGA7 PLXNA1	7.41e-05	192	52	4	26d9207e72bbef5e0046de511e2c9ff752b726f3
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA LRRTM2 PLCD4 EDIL3	7.56e-05	193	52	4	146e8c148478ab61b1c1dbaf1ee98a8cd4a0ff8a
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ELAPOR2 PTPN13 DHCR7 CTSH	7.56e-05	193	52	4	ba484fa1f290a92ae02475a4c468b4ac840c133e
ToppCell	normal_Lung-Epithelial_cells-AT2\|normal_Lung / Location, Cell class and cell subclass	ELAPOR2 PTPN13 PON2 CTSH	7.56e-05	193	52	4	80ad1bdc50ecb8a50362f718248441cae20904a6
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNA P2RX1 ITGA7 PLXNA1	7.56e-05	193	52	4	88916d9a7d831eb52848599917c04238f8f9812b
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNA P2RX1 ITGA7 PLXNA1	7.56e-05	193	52	4	7fc3ab7261c88c1df71744bf5b17e8e46c4300e0
ToppCell	(7)_Epithelial_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ELAPOR2 PTPN13 PON2 CTSH	7.72e-05	194	52	4	413e8b9f1e15be363a7f4a8f727af3eeb9e9a928
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA P2RX1 ITGA7 EDIL3	7.72e-05	194	52	4	5c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCell	AT2\|World / shred by cell class for parenchyma	ACSL1 ELAPOR2 PTPN13 CTSH	7.72e-05	194	52	4	e773f5ef3abce7113a6b7cc7cbe68de873d4a17f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA P2RX1 ITGA7 EDIL3	7.72e-05	194	52	4	ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCell	343B-Epithelial_cells-Epithelial-D_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	PSAT1 DHCR7 PON2 CTSH	7.72e-05	194	52	4	3944b00a64428579874e1ebd94ef35a294017658
ToppCell	343B-Epithelial_cells-Epithelial-D_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	PSAT1 DHCR7 PON2 CTSH	7.72e-05	194	52	4	5af1f0ca4c46d9368e5defe33b30c7b4382202bb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA P2RX1 ITGA7 EDIL3	7.72e-05	194	52	4	ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PSAT1 DHCR7 PON2 CTSH	7.87e-05	195	52	4	643a360d3358bad52f0737c0d55195b69007c29b
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ELAPOR2 PTPN13 DHCR7 CTSH	7.87e-05	195	52	4	3e24570def013d5b0b1ef1d7a5ced7dfd922590b
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ELAPOR2 PTPN13 DHCR7 CTSH	7.87e-05	195	52	4	955a0a7244cd7eaf006a39e1bd03333baf6f30a4
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ELAPOR2 PTPN13 DHCR7 CTSH	7.87e-05	195	52	4	6617abca0009ad3d8731f515f91ab275f9ea4c40
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ELAPOR2 PTPN13 DHCR7 CTSH	7.87e-05	195	52	4	6867f9c56ea27a17c8c4099aae0d79903c3748a5
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ELAPOR2 PTPN13 DHCR7 CTSH	7.87e-05	195	52	4	37aa6e4123d37de4de42ca68d3020f2a7686ce02
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ELAPOR2 PTPN13 DHCR7 CTSH	7.87e-05	195	52	4	fc0ae145a2118df7cbbc9ac4ca9dc12d26c087c4
ToppCell	3'-Parenchyma_lung-Epithelial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ELAPOR2 PTPN13 DHCR7 CTSH	7.87e-05	195	52	4	eec187c087e432417bc346c5d3ead72f58bf3215
ToppCell	356C-Epithelial_cells-Epithelial-A_(AT2)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	ELAPOR2 PTPN13 PON2 CTSH	8.03e-05	196	52	4	4715f19f844e7244fc4bc446cba7c8088c600fc3
ToppCell	cellseq-Epithelial-Epithelial_Alveolar\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ELAPOR2 PTPN13 DHCR7 CTSH	8.03e-05	196	52	4	a7cbe66ebd8931ef2b8ff26a42afce0ad1c48f17
ToppCell	356C-Epithelial_cells-Epithelial-A_(AT2)\|356C / Donor, Lineage, Cell class and subclass (all cells)	ELAPOR2 PTPN13 PON2 CTSH	8.03e-05	196	52	4	93a5d9b8bcff7d07596ef1f4f2b74f043835fc69
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FLNA ABCA1 ITGA7 PLXNA1	8.03e-05	196	52	4	b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FLNA PAPPA ITGA7 EDIL3	8.03e-05	196	52	4	40cae477b3906623d1f2a4c630279e710499ce80
ToppCell	356C-Epithelial_cells-Epithelial-B_(AT2)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	PTPN13 DHCR7 PON2 CTSH	8.19e-05	197	52	4	06ed8f293d4ee89f14dc2f43d6cae93bbc02508a
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	PTPN13 GALK2 CTSH PLAAT5	8.19e-05	197	52	4	6b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	FLNA PSAT1 PON2 CTSH	8.19e-05	197	52	4	965d5a3f8c9b12cb8a8d3429702ae29ebd8c6122
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial-Astroglia\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	FLNA PSAT1 PON2 CTSH	8.19e-05	197	52	4	3f088eb29197bc575400d6dafd8083e69e4a149f
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon\|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.	ABCA1 PON2 ITGA7 CTSH	8.19e-05	197	52	4	58b957efd006f43c2fe55071d5c6d06c2e367e72
ToppCell	356C-Epithelial_cells-Epithelial-B_(AT2)\|356C / Donor, Lineage, Cell class and subclass (all cells)	PTPN13 DHCR7 PON2 CTSH	8.19e-05	197	52	4	c115d0a45545ed24259ad88872231bf4d4d389d2
ToppCell	Epithelial_cells-AT2_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	ACSL1 ELAPOR2 DHCR7 CTSH	8.19e-05	197	52	4	59aa28a377315dfcda4d9b6ecd3419157654f24e
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon\|organoid_Velasco_nature / Sample Type, Dataset, Time_group, and Cell type.	ABCA1 PON2 ITGA7 CTSH	8.35e-05	198	52	4	a6f65bb0845d8f64f5c7edb00cee3ca5adb1a373
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TRIM46 FLNA ELAPOR2 ITGA7	8.35e-05	198	52	4	1e1ea54f0c234f3b6d29064c4881d8a0c0949a75
ToppCell	tumor_Lung-Fibroblasts-Smooth_muscle_cells\|Fibroblasts / Location, Cell class and cell subclass	FLNA ATRNL1 ITGA7 EDIL3	8.35e-05	198	52	4	f540f464118edc0fb809ebcb813d0302e6952253
ToppCell	AT2_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	ELAPOR2 PTPN13 DHCR7 CTSH	8.35e-05	198	52	4	893036558a9ad86b57f9e735df35812e9d18739e
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	PSAT1 OAF PON2 TKTL1	8.51e-05	199	52	4	75ff9a5df156c6632883eab79573f1c02c985803
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	OAF SLC17A7 NHS NMNAT3	8.51e-05	199	52	4	a13f4b8a039304e685464cc8879659824cad5a3e
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ATRNL1 DHCR7 LRRTM2 EDIL3	8.51e-05	199	52	4	333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ATRNL1 DHCR7 LRRTM2 EDIL3	8.51e-05	199	52	4	e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ELAPOR2 PTPN13 DHCR7 CTSH	8.51e-05	199	52	4	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	ELAPOR2 PTPN13 DHCR7 PON2	8.51e-05	199	52	4	e459d5aa63c83f960562be33cea8182b0556eabf
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ABCA1 DHCR7 PAPPA GABBR2	8.51e-05	199	52	4	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	Biopsy_IPF-Epithelial-AT2\|Biopsy_IPF / Sample group, Lineage and Cell type	ELAPOR2 PTPN13 PON2 CTSH	8.51e-05	199	52	4	c841d475703d3489161fb7904526bd7563d5fb0f
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_2_alveolar\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	ELAPOR2 PTPN13 DHCR7 PON2	8.51e-05	199	52	4	e28ace2ca680c6154398e17110aa1838dd7a5548
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PAPPA2 FLNA ATRNL1 NMNAT3	8.68e-05	200	52	4	8988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Stem_cells\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	FANCD2 PSAT1 PON2 TKTL1	8.68e-05	200	52	4	b71138729d2a81cc2f30e3bc15853516a525a17f
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Macroglial-Astrocyte\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	PSAT1 OAF PON2 TKTL1	8.68e-05	200	52	4	7205e742ad796d548761839d92a4794ee8f17629
ToppCell	Biopsy_IPF-Epithelial-KRT5-/KRT17+\|Biopsy_IPF / Sample group, Lineage and Cell type	PON2 PAPPA GABBR2 EDIL3	8.68e-05	200	52	4	2fc7a3b3aea711ad3d96fd9513f4b40533056d86
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNA NHS ITGA7 EDIL3	8.68e-05	200	52	4	a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-RGCs_3\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	PSAT1 OAF PON2 TKTL1	8.68e-05	200	52	4	55a1df656545ff078b727d55e4d65d61ddb5c41f
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PAPPA2 FLNA ATRNL1 NMNAT3	8.68e-05	200	52	4	87827041663013f5e7273168dc8709d69840e7ce
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Stem_cells-Stem_cells\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	FANCD2 PSAT1 PON2 TKTL1	8.68e-05	200	52	4	8f3067b52865a0f5488e4df0d5a4fea80135cef5
ToppCell	BAL-Control-cDC_7\|Control / Compartment, Disease Groups and Clusters	MKKS KMT2D ACY1	3.81e-04	121	52	3	b49b044a687a31883dfccecf10a183b5ba567f7a
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Mup5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FANCD2 PAPPA2 FGF5	4.39e-04	127	52	3	6df92f80b8922ca00eb383f79cd8dda4d602adfc
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 NHS FGF5	4.91e-04	132	52	3	182973660929fe4174e0354c85863a25518c18c1
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Nxph2_Sla\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FANCD2 PAPPA2 ITGA7	5.13e-04	134	52	3	6d97fa07f55ae20c17b9d5262e893957cccc6dba
Drug	dehydroepiandrosterone sulfate	MKKS ACSL1 ACSL6 P2RX1 AACS PON2 GABBR2	3.06e-06	277	52	7	CID000005244
Drug	0179445-0000 [211246-22-9]; Up 200; 1uM; MCF7; HT_HG-U133A	ATRNL1 SLC17A7 FGF5 PAPPA ITGA7 EDIL3	6.02e-06	199	52	6	3633_UP
Disease	Phyllodes Tumor	FLNA KMT2D	2.80e-05	5	50	2	C0010701
Disease	Malignant Cystosarcoma Phyllodes	FLNA KMT2D	2.80e-05	5	50	2	C0600066
Disease	obesity (biomarker_via_orthology)	ACSL1 ABCA1 AACS PON2	1.14e-04	147	50	4	DOID:9970 (biomarker_via_orthology)
Disease	Hyperlipoproteinemia Type IIb	ABCA1 PON2	2.17e-04	13	50	2	C1704417
Disease	Hyperlipoproteinemia Type IIa	ABCA1 PON2	3.33e-04	16	50	2	C0745103
Disease	Hypercholesterolemia, Familial	ABCA1 PON2	4.23e-04	18	50	2	C0020445
Disease	lung squamous cell carcinoma (is_implicated_in)	KMT2D PTPN13	7.58e-04	24	50	2	DOID:3907 (is_implicated_in)
Disease	triacylglycerol 56:5 measurement	ZNF836 EDIL3	8.91e-04	26	50	2	EFO_0010432
Disease	Epileptic encephalopathy	FLNA GABBR2	1.19e-03	30	50	2	C0543888
Disease	Huntington disease, disease progression measurement	ATRNL1 MINDY4	1.19e-03	30	50	2	EFO_0008336, MONDO_0007739
Disease	Alzheimer disease	FANCD2 ACSL6 ABCA1 TRIM56 CTSH	1.35e-03	485	50	5	MONDO_0004975

Protein segments in the cluster

Peptide	Gene	Start	Entry
HGDYCRINPKTGGIV	AACS	521	Q86V21
GEVCVKGPNVFQGYL	ACSL1	506	P33121
YQAVSRIVCGHPEGG	ABCA1	301	O95477
DFCHKFLPGYVGGIQ	DHCR7	116	Q9UBM7
KGVVPDNHPYCVGAA	HACL1	251	Q9UJ83
IGYGHRVITDQCPEG	KCNJ9	121	Q92806
GRLKQLHNGFGGYVC	MKKS	41	Q9NPJ1
HEGPFIIINGYGQCK	LRRTM2	491	O43300
QSGQRGYECLFHIPG	PLXNA1	736	Q9UIW2
AGYEVCQHEVLGGGR	MYLK3	511	Q32MK0
PGRVNIIGEHIDYCG	GALK2	41	Q01415
YKDGVVTIGCVGFPN	GNL1	356	P36915
IHGSGYCGDGIIQKD	PAPPA	941	Q13219
HQVYGKEACIPCGPG	ELAPOR2	646	A8MWY0
VGCHPNGQKLFVYDP	PON2	281	Q15165
GIGFHLQIYPDGKVN	FGF5	96	P12034
LNHIHGAPYCGDGKV	PAPPA2	1106	Q9BXP8
IGYVCKCPRGFNGIH	EDIL3	101	O43854
PGVCLKYVGGDQFGH	ILRUN	111	Q9H6K1
QPGKYVICVRFGGEH	FLNA	1716	P21333
GQEFHFGPCQVKGVV	IL24	51	Q13007
VPETKGAIVQGGYGH	ATRNL1	456	Q5VV63
HAVLAVGYGEKNGIP	CTSH	281	P09668
IKYGPNHLMVFGGVC	GABBR2	121	O75899
QGPGGKIVTCAHRYE	ITGA7	131	Q13683
NHGVVDGPGVKVQEY	FANCD2	1041	Q9BXW9
RHGGIYVKAVIPQGA	PTPN13	1391	Q12923
KQTQGYCAEHPEGGI	P2RX1	111	P51575
CAREVLGQQGYIGHG	TRIM46	56	Q7Z4K8
GHFRQNGGCGYVLKP	PLCD4	591	Q9BRC7
VCHYAALGPENGQGV	NHS	801	Q6T4R5
VPDNYKVIFLQGGGC	PSAT1	66	Q9Y617
GYIVTQIPGGFICQK	SLC17A7	126	Q9P2U7
QVGDHGKPCVCRYGL	OAF	206	Q86UD1
GLGCQKVEVAPGYVV	ACY1	46	Q03154
GEICVRGPNVFKGYL	ACSL6	506	Q9UKU0
FIVKPDGGCQGDGIY	TTLL11	336	Q8NHH1
VHQGIHTGVKPYGCI	ZNF268	461	Q14587
YGIVQNKGGPCGVLA	MINDY4	446	Q4G0A6
HVVSQAGGPEGKDYC	SPPL2B	31	Q8TCT7
NRFGGGPAVNHLYVC	USP20	766	Q9Y2K6
SQPVKCGHVEGLLYG	ZNFX1	1411	Q9P2E3
IHTGERPYVCGQCGK	ZNF416	291	Q9BWM5
IVHQEIHTGGKPYGC	ZNF26	246	P17031
YGTIPQIFGKGECAR	VPS33A	186	Q96AX1
GNCEHFVNGLRYGVP	PLAAT5	231	Q96KN8
HYPQGGIGEAVCAAV	TKTL1	536	P51854
CIHGGVPPRKAGYIE	USP33	766	Q8TEY7
IVHTRGKPYQCGVCG	ZNF836	266	Q6ZNA1
QVVGEYKGPGLHGCQ	TRIM56	666	Q9BRZ2
DALYVACQGQPKGGH	KMT2D	386	O14686
GLVCVGRVGHDPKGY	NMNAT3	161	Q96T66