Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Ig-like_fold	FNDC3B FLNA SDK2 MXRA5 HLA-DOB EBF3 LILRB2 HLA-DRA EBF2 CADM1 NECTIN2 COL14A1 SIGLEC11 SIGLEC1 PLXNA1	5.07e-06	706	100	15	IPR013783
Domain	-	FNDC3B FLNA SDK2 MXRA5 HLA-DOB EBF3 HLA-DRA EBF2 CADM1 NECTIN2 COL14A1 SIGLEC11 SIGLEC1 PLXNA1	1.16e-05	663	100	14	2.60.40.10
Domain	C2-set_2	CADM1 NECTIN2 SIGLEC11 SIGLEC1	6.73e-05	41	100	4	PF08205
Domain	CD80_C2-set	CADM1 NECTIN2 SIGLEC11 SIGLEC1	6.73e-05	41	100	4	IPR013162
Domain	P53	TP63 TP73	8.48e-05	3	100	2	PF00870
Domain	P53	TP63 TP73	8.48e-05	3	100	2	PS00348
Domain	-	TP63 TP73	8.48e-05	3	100	2	4.10.170.10
Domain	p53_DNA-bd	TP63 TP73	8.48e-05	3	100	2	IPR011615
Domain	p53_tetrameristn	TP63 TP73	8.48e-05	3	100	2	IPR010991
Domain	P53_tetramer	TP63 TP73	8.48e-05	3	100	2	PF07710
Domain	p53_tumour_suppressor	TP63 TP73	8.48e-05	3	100	2	IPR002117
Domain	Transcription_factor_COE	EBF3 EBF2	1.69e-04	4	100	2	IPR003523
Domain	WWE	DTX4 DTX2	1.69e-04	4	100	2	SM00678
Domain	COE_HLH	EBF3 EBF2	1.69e-04	4	100	2	IPR032201
Domain	COE_DBD	EBF3 EBF2	1.69e-04	4	100	2	IPR032200
Domain	WWE-dom_subgr	DTX4 DTX2	1.69e-04	4	100	2	IPR018123
Domain	Transcription_factor_COE_CS	EBF3 EBF2	1.69e-04	4	100	2	IPR018350
Domain	COE1_HLH	EBF3 EBF2	1.69e-04	4	100	2	PF16423
Domain	COE1_DBD	EBF3 EBF2	1.69e-04	4	100	2	PF16422
Domain	COE	EBF3 EBF2	1.69e-04	4	100	2	PS01345
Domain	Ig_E-set	FLNA EBF3 EBF2 SAG PLXNA1	2.41e-04	104	100	5	IPR014756
Domain	IPT	EBF3 EBF2 PLXNA1	3.97e-04	27	100	3	SM00429
Domain	p53/RUNT-type_TF_DNA-bd	TP63 TP73	4.20e-04	6	100	2	IPR012346
Domain	-	TP63 TP73	4.20e-04	6	100	2	2.60.40.720
Domain	TIG	EBF3 EBF2 PLXNA1	6.00e-04	31	100	3	PF01833
Domain	IPT	EBF3 EBF2 PLXNA1	6.60e-04	32	100	3	IPR002909
Domain	IG_LIKE	SDK2 MXRA5 HLA-DOB LILRB2 HLA-DRA CADM1 NECTIN2 SIGLEC11 SIGLEC1	1.28e-03	491	100	9	PS50835
Domain	Ig-like_dom	SDK2 MXRA5 HLA-DOB LILRB2 HLA-DRA CADM1 NECTIN2 SIGLEC11 SIGLEC1	1.51e-03	503	100	9	IPR007110
Domain	WWE	DTX4 DTX2	1.81e-03	12	100	2	PS50918
Domain	WWE	DTX4 DTX2	1.81e-03	12	100	2	PF02825
Domain	WWE-dom	DTX4 DTX2	1.81e-03	12	100	2	IPR004170
Domain	SEA	MUC3B MUC16	2.48e-03	14	100	2	SM00200
Domain	MHC_II_a/b_N	HLA-DOB HLA-DRA	2.48e-03	14	100	2	IPR014745
Domain	-	HLA-DOB HLA-DRA	2.48e-03	14	100	2	3.10.320.10
Domain	Ig_I-set	SDK2 MXRA5 CADM1 SIGLEC11 SIGLEC1	3.57e-03	190	100	5	IPR013098
Domain	I-set	SDK2 MXRA5 CADM1 SIGLEC11 SIGLEC1	3.57e-03	190	100	5	PF07679
Domain	Laminin_G	EYS FAT1 COL14A1	3.71e-03	58	100	3	IPR001791
Domain	Ig/MHC_CS	HLA-DOB HLA-DRA SIGLEC11	3.71e-03	58	100	3	IPR003006
Domain	IG_MHC	HLA-DOB HLA-DRA SIGLEC11	4.09e-03	60	100	3	PS00290
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ABCC3 FLNA HIVEP2 SH2B3 MEX3D MTMR8 HECTD4 POLRMT TTC3 NCOR1 FAT1 ZNF341 TP53I13 DTX2 DHX34 ULK2 PLXNA1	3.58e-08	1105	105	17	35748872
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	CCDC8 PMS2 LEMD3 GRAMD1A MTMR8 KIAA1549 MSH2 ZNF362 FAM171A1 NCOR1 CADM1 BABAM1 NECTIN2 PLEKHA1 NEURL4 AGTPBP1	1.06e-07	1049	105	16	27880917
Pubmed	Three-dimensional reconstruction of protein networks provides insight into human genetic disease.	PMS2 TP63 TP73	5.31e-07	6	105	3	22252508
Pubmed	Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.	EBF3 EBF2 ATP2A1	9.28e-07	7	105	3	24786561
Pubmed	Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.	ABCC3 CHST10 HLA-DOB LILRB2 HLA-DRA UGT8 ENPP5	2.48e-06	198	105	7	27480124
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZSWIM8 ERBB4 HLA-DRA POLRMT ADNP2 KIAA1549 U2AF2 ZNF362 FAT1 RESF1 SIGLEC1 DHX34 AGTPBP1 TP73	6.87e-06	1116	105	14	31753913
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ZSWIM8 PMS2 HIVEP2 SYNE1 HLA-DRA HECTD4 ADNP2 IDS TTC3 CADM1 PAK1 PKNOX1 ENPP5 CARS2 AGTPBP1	7.43e-06	1285	105	15	35914814
Pubmed	Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem.	EBF3 EBF2 TP73	7.48e-06	13	105	3	22421355
Pubmed	FAT1 and MSH2 Are Predictive Prognostic Markers for Chinese Osteosarcoma Patients Following Chemotherapeutic Treatment.	MSH2 FAT1	9.03e-06	2	105	2	35279875
Pubmed	Tumor-specific p73 up-regulation mediates p63 dependence in squamous cell carcinoma.	TP63 TP73	9.03e-06	2	105	2	17018588
Pubmed	Evidence for the lack of mismatch-repair directed antirecombination during mouse meiosis.	PMS2 MSH2	9.03e-06	2	105	2	12195036
Pubmed	Conformational stability and activity of p73 require a second helix in the tetramerization domain.	TP63 TP73	9.03e-06	2	105	2	19763140
Pubmed	Tyrosyl phosphorylated PAK1 regulates breast cancer cell motility in response to prolactin through filamin A.	FLNA PAK1	9.03e-06	2	105	2	23340249
Pubmed	p73 and p63 regulate the expression of fibroblast growth factor receptor 3.	TP63 TP73	9.03e-06	2	105	2	20298673
Pubmed	Vibrio vulnificus RtxA1 cytotoxin targets filamin A to regulate PAK1- and MAPK-dependent cytoskeleton reorganization and cell death.	FLNA PAK1	9.03e-06	2	105	2	31237474
Pubmed	Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q.	PMS2 TP73	9.03e-06	2	105	2	18768816
Pubmed	p63 and p73 do not contribute to p53-mediated lymphoma suppressor activity in vivo.	TP63 TP73	9.03e-06	2	105	2	16007185
Pubmed	Induction of Myc-intron-binding polypeptides MIBP1 and RFX1 during retinoic acid-mediated differentiation of haemopoietic cells.	HIVEP2 RFX1	9.03e-06	2	105	2	10642512
Pubmed	The Role of p63 and p73 in tumor formation and progression: coming of age toward clinical usefulness. Commentary re: F. Koga et al., Impaired p63 expression associates with poor prognosis and uroplakin III expression in invasive urothelial carcinoma of the bladder. Clin. Cancer Res., 9: 5501-5507, 2003, and P. Puig et al., p73 Expression in human normal and tumor tissues: loss of p73alpha expression is associated with tumor progression in bladder Cancer. Clin. Cancer Res., 9: 5642-5651, 2003.	TP63 TP73	9.03e-06	2	105	2	14654522
Pubmed	The p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers.	TP63 TP73	9.03e-06	2	105	2	17446929
Pubmed	Expression of sucrase-isomaltase and dipeptidylpeptidase IV in human small intestine and colon.	DPP4 SI	9.03e-06	2	105	2	1677636
Pubmed	Identification of actin binding protein, ABP-280, as a binding partner of human Lnk adaptor protein.	FLNA SH2B3	9.03e-06	2	105	2	11163396
Pubmed	Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1.	FLNA PAK1	9.03e-06	2	105	2	12198493
Pubmed	p63 and p73 expression in extrahepatic bile duct carcinoma and their clinical significance.	TP63 TP73	9.03e-06	2	105	2	17385050
Pubmed	p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis.	TP63 TP73	9.03e-06	2	105	2	16413471
Pubmed	The role of p53 protein family in gastrointestinal malignancies.	TP63 TP73	9.03e-06	2	105	2	16557273
Pubmed	SynCAM1, a synaptic adhesion molecule, is expressed in astrocytes and contributes to erbB4 receptor-mediated control of female sexual development.	ERBB4 CADM1	9.03e-06	2	105	2	21486934
Pubmed	The 5th International p63/p73 Workshop: much more than just tumour suppression.	TP63 TP73	9.03e-06	2	105	2	22240899
Pubmed	Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization.	TP63 TP73	9.03e-06	2	105	2	27716744
Pubmed	Polymorphisms in the p63 and p73 genes are associated with ovarian cancer risk and clinicopathological variables.	TP63 TP73	9.03e-06	2	105	2	23095717
Pubmed	P634A4 and TAp73 immunocytochemistry in liquid-based cervical cytology--potential biomarkers for diagnosis and progress prediction of cervical neoplasia.	TP63 TP73	9.03e-06	2	105	2	20081800
Pubmed	Distinct p63 and p73 Protein Interactions Predict Specific Functions in mRNA Splicing and Polyploidy Control in Epithelia.	TP63 TP73	9.03e-06	2	105	2	33375680
Pubmed	p63 and p73: roles in development and tumor formation.	TP63 TP73	9.03e-06	2	105	2	15280445
Pubmed	p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53.	TP63 TP73	9.03e-06	2	105	2	10373484
Pubmed	TP63 and TP73 in cancer, an unresolved "family" puzzle of complexity, redundancy and hierarchy.	TP63 TP73	9.03e-06	2	105	2	24983500
Pubmed	Role of p63 and p73 isoforms on the cell death in patients with hepatocellular carcinoma submitted to orthotopic liver transplantation.	TP63 TP73	9.03e-06	2	105	2	28350813
Pubmed	Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin.	PMS2 TP73	9.03e-06	2	105	2	12601175
Pubmed	Genome-wide mapping indicates that p73 and p63 co-occupy target sites and have similar dna-binding profiles in vivo.	TP63 TP73	9.03e-06	2	105	2	20644729
Pubmed	Tissue-specific expression of p73 and p63 isoforms in human tissues.	TP63 TP73	9.03e-06	2	105	2	34315849
Pubmed	p63 antagonizes p53 to promote the survival of embryonic neural precursor cells.	TP63 TP73	9.03e-06	2	105	2	19458240
Pubmed	Tumors arising in DNA mismatch repair-deficient mice show a wide variation in mutation frequency as assessed by a transgenic reporter gene.	PMS2 MSH2	9.03e-06	2	105	2	10837019
Pubmed	Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process.	PMS2 MSH2	9.03e-06	2	105	2	9697842
Pubmed	While p73 is essential, p63 is completely dispensable for the development of the central nervous system.	TP63 TP73	9.03e-06	2	105	2	21293190
Pubmed	Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes.	PMS2 MSH2	2.70e-05	3	105	2	10430621
Pubmed	Neuronal survival and p73/p63/p53: a family affair.	TP63 TP73	2.70e-05	3	105	2	15359011
Pubmed	The p53-family members p63 and p73 inhibit insulin-like growth factor-I receptor gene expression in colon cancer cells.	TP63 TP73	2.70e-05	3	105	2	16181796
Pubmed	Glyoxalase II, a detoxifying enzyme of glycolysis byproduct methylglyoxal and a target of p63 and p73, is a pro-survival factor of the p53 family.	TP63 TP73	2.70e-05	3	105	2	16831876
Pubmed	The integrin alpha(v)beta(3-5) ligand MFG-E8 is a p63/p73 target gene in triple-negative breast cancers but exhibits suppressive functions in ER(+) and erbB2(+) breast cancers.	TP63 TP73	2.70e-05	3	105	2	21127199
Pubmed	Regulation and function of the p53-related proteins: same family, different rules.	TP63 TP73	2.70e-05	3	105	2	10754563
Pubmed	p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress.	TP63 TP73	2.70e-05	3	105	2	16601753
Pubmed	Differential expression of p53 gene family members p63 and p73 in head and neck squamous tumorigenesis.	TP63 TP73	2.70e-05	3	105	2	11957139
Pubmed	The characterization of the Olf-1/EBF-like HLH transcription factor family: implications in olfactory gene regulation and neuronal development.	EBF3 EBF2	2.70e-05	3	105	2	9151732
Pubmed	p63 and p73 coordinate p53 function to determine the balance between survival, cell death, and senescence in adult neural precursor cells.	TP63 TP73	2.70e-05	3	105	2	24809925
Pubmed	Crystal structures of the DNA-binding domain tetramer of the p53 tumor suppressor family member p73 bound to different full-site response elements.	TP63 TP73	2.70e-05	3	105	2	23243311
Pubmed	p53, p63 and p73--solos, alliances and feuds among family members.	TP63 TP73	2.70e-05	3	105	2	11825686
Pubmed	Population-based study of the association of variants in mismatch repair genes with prostate cancer risk and outcomes.	PMS2 MSH2	2.70e-05	3	105	2	20056646
Pubmed	The dominant-negative interplay between p53, p63 and p73: A family affair.	TP63 TP73	2.70e-05	3	105	2	27589690
Pubmed	Apoptosis and mutation in the murine small intestine: loss of Mlh1- and Pms2-dependent apoptosis leads to increased mutation in vivo.	PMS2 MSH2	2.70e-05	3	105	2	12967659
Pubmed	ΔNp63 regulates select routes of reprogramming via multiple mechanisms.	TP63 TP73	2.70e-05	3	105	2	24013722
Pubmed	Interaction between TP63 and MDM2 genes and the risk of recurrent pregnancy loss.	TP63 TP73	2.70e-05	3	105	2	25218545
Pubmed	Gene expression profile and mutational analysis of DNA mismatch repair genes in carcinoma prostate in Indian population.	PMS2 MSH2	2.70e-05	3	105	2	21348638
Pubmed	[Clinical significance of the expression of p53, p63 and p73 in nasal and paranasal sinus carcinoma].	TP63 TP73	2.70e-05	3	105	2	19119599
Pubmed	p63 and p73 are not required for the development and p53-dependent apoptosis of T cells.	TP63 TP73	2.70e-05	3	105	2	15261144
Pubmed	Localization and enhanced current density of the Kv4.2 potassium channel by interaction with the actin-binding protein filamin.	FLNA KCND2	2.70e-05	3	105	2	11102480
Pubmed	Diverse p63 and p73 isoforms regulate Δ133p53 expression through modulation of the internal TP53 promoter activity.	TP63 TP73	2.70e-05	3	105	2	22075982
Pubmed	Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family.	TP63 TP73	2.70e-05	3	105	2	15837625
Pubmed	Structural evolution of p53, p63, and p73: implication for heterotetramer formation.	TP63 TP73	2.70e-05	3	105	2	19815500
Pubmed	Filamin A negatively regulates the transcriptional activity of p73alpha in the cytoplasm.	FLNA TP73	2.70e-05	3	105	2	17825253
Pubmed	deltaEF1 repressor controls selectively p53 family members during differentiation.	TP63 TP73	2.70e-05	3	105	2	16007124
Pubmed	Core2 O-glycan structure is essential for the cell surface expression of sucrase isomaltase and dipeptidyl peptidase-IV during intestinal cell differentiation.	DPP4 SI	2.70e-05	3	105	2	20841351
Pubmed	Intrinsic aggregation propensity of the p63 and p73 TI domains correlates with p53R175H interaction and suggests further significance of aggregation events in the p53 family.	TP63 TP73	2.70e-05	3	105	2	27447112
Pubmed	p63 and p73 are required for p53-dependent apoptosis in response to DNA damage.	TP63 TP73	2.70e-05	3	105	2	11932750
Pubmed	Tumor suppressors p53, p63TAα, p63TAy, p73α, and p73β use distinct pathways to repress telomerase expression.	TP63 TP73	2.70e-05	3	105	2	22496369
Pubmed	T cells develop normally in the absence of both Deltex1 and Deltex2.	DTX4 DTX2	2.70e-05	3	105	2	16923970
Pubmed	A novel response element confers p63- and p73-specific activation of the WNT4 promoter.	TP63 TP73	2.70e-05	3	105	2	16343436
Pubmed	Novel therapeutic interventions for p53-altered tumors through manipulation of its family members, p63 and p73.	TP63 TP73	2.70e-05	3	105	2	26652033
Pubmed	Association of plasminogen with dipeptidyl peptidase IV and Na+/H+ exchanger isoform NHE3 regulates invasion of human 1-LN prostate tumor cells.	DPP4 SLC9A3	2.70e-05	3	105	2	15911629
Pubmed	Differential expression of p53, p63 and p73 proteins in human buccal squamous-cell carcinomas.	TP63 TP73	2.70e-05	3	105	2	12969350
Pubmed	Evaluating the Influence of a G-Quadruplex Prone Sequence on the Transactivation Potential by Wild-Type and/or Mutant P53 Family Proteins through a Yeast-Based Functional Assay.	TP63 TP73	2.70e-05	3	105	2	33672023
Pubmed	p53 Family isoforms.	TP63 TP73	2.70e-05	3	105	2	18289041
Pubmed	Mismatch repair deficiency screening in colorectal carcinoma by a four-antibody immunohistochemical panel in Pakistani population and its correlation with histopathological parameters.	PMS2 MSH2	2.70e-05	3	105	2	28651545
Pubmed	Differential regulation of vitamin D receptor (VDR) by the p53 Family: p73-dependent induction of VDR upon DNA damage.	TP63 TP73	2.70e-05	3	105	2	17716971
Pubmed	Alterations in PMS2, MSH2 and MLH1 expression in human prostate cancer.	PMS2 MSH2	2.70e-05	3	105	2	12684669
Pubmed	iASPP inhibits p53-independent apoptosis by inhibiting transcriptional activity of p63/p73 on promoters of proapoptotic genes.	TP63 TP73	2.70e-05	3	105	2	22538442
Pubmed	The emerging p53 gene family.	TP63 TP73	2.70e-05	3	105	2	10203277
Pubmed	Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues.	PMS2 MSH2	2.70e-05	3	105	2	23071719
Pubmed	Shared Signature of Recent Positive Selection on the TSBP1-BTNL2-HLA-DRA Genes in Five Native Populations from North Borneo.	HLA-DRA TSBP1	2.70e-05	3	105	2	33022050
Pubmed	The tumor suppressors p53, p63, and p73 are regulators of microRNA processing complex.	TP63 TP73	2.70e-05	3	105	2	20485546
Pubmed	Melanocyte and keratinocyte carcinogenesis: p53 family protein activities and intersecting mRNA expression profiles.	TP63 TP73	2.70e-05	3	105	2	16363065
Pubmed	Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions.	PMS2 MSH2	2.70e-05	3	105	2	11828012
Pubmed	The p53 family: guardians of maternal reproduction.	TP63 TP73	2.70e-05	3	105	2	21427767
Pubmed	Physical interaction with Yes-associated protein enhances p73 transcriptional activity.	TP63 TP73	2.70e-05	3	105	2	11278685
Pubmed	Expression of p53 family in scars.	TP63 TP73	2.70e-05	3	105	2	14757278
Pubmed	S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation.	TP63 TP73	2.70e-05	3	105	2	16449968
Pubmed	Expression of p53 family genes in urinary bladder cancer: correlation with disease aggressiveness and recurrence.	TP63 TP73	2.70e-05	3	105	2	24213852
Pubmed	Prevalence of CNV-neutral structural genomic rearrangements in MLH1, MSH2, and PMS2 not detectable in routine NGS diagnostics.	PMS2 MSH2	2.70e-05	3	105	2	32002723
Pubmed	Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain.	TP63 TP73	2.70e-05	3	105	2	30099987
Pubmed	How the TP53 family proteins TP63 and TP73 contribute to tumorigenesis: regulators and effectors.	TP63 TP73	2.70e-05	3	105	2	24488880
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CCDC8 LEMD3 SYNE1 GRAMD1A POLRMT KIAA1549 TTC3 FAM171A1 GUSB NECTIN2 PLEKHA1 COL14A1 CARS2 NEURL4 AGTPBP1	4.07e-05	1487	105	15	33957083
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	DPP4 ERBB4 MTMR8 MUC16 U2AF2 APOB EYS AGTPBP1	4.25e-05	420	105	8	28065597
Interaction	SH2B3 interactions	FLNA ERBB4 SH2B3 BABAM1	7.49e-06	25	103	4	int:SH2B3
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	CADM1 NECTIN2 SIGLEC11 SIGLEC1	2.00e-05	40	73	4	592
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	SECISBP2L TMEM185B EBF3 KIAA1549 XKR6 IDS TTC3 EBF2 CADM1 ATP8A1 RBMS3 PLEKHA1 BSN PLXNA1 AGTPBP1 RBFOX2	7.32e-06	1106	104	16	M39071
Coexpression	MCBRYAN_PUBERTAL_BREAST_6_7WK_UP	SECISBP2L ABCC3 SH2B3 EBF3 RESF1 ATP8A1 GUSB	1.49e-05	199	104	7	MM991
Coexpression	MCBRYAN_PUBERTAL_BREAST_6_7WK_UP	SECISBP2L ABCC3 SH2B3 EBF3 RESF1 ATP8A1 GUSB	1.49e-05	199	104	7	M2155
Coexpression	HEVNER_CORTICAL_PLATE_POSTMITOTIC_NEURONS	CHST10 KIAA1549 TMEM44 PAK1 BSN AGTPBP1	1.75e-05	136	104	6	MM407
Coexpression	LUI_THYROID_CANCER_CLUSTER_2	SECISBP2L ABCC3 SYNE1 HECTD4	2.56e-05	43	104	4	M7343
Coexpression	WINTER_HYPOXIA_DN	HLA-DOB SYNE1 RESF1 ATP8A1	5.47e-05	52	104	4	M2683
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HIVEP2 SYNE1 XKR6 IDS TTC3 KCND2 SLC2A13 RBFOX2	2.19e-08	198	104	8	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 XKR6 IDS KCND2 PAK1 SLC2A13 RBFOX2	4.26e-07	198	104	7	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SECISBP2L DPP4 ERBB4 SYNE1 MBIP CADM1 ATP8A1	4.40e-07	199	104	7	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 FAM171A1 SLC9A3 CADM1 UGT8 SLC2A13	3.52e-06	175	104	6	e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 STAB2 CADM1 COL14A1 SIGLEC1 PLXNA1	3.75e-06	177	104	6	26bad614560609d318bfc9c235a698bca4e1c22c
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	SECISBP2L ERBB4 SYNE1 MBIP CADM1 ATP8A1	4.14e-06	180	104	6	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 FAM171A1 SLC9A3 CADM1 UGT8 SLC2A13	4.55e-06	183	104	6	31ab55d5f3639f5964541d5eae23044dbda3356e
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SECISBP2L ERBB4 MBIP FAT1 CADM1 ATP8A1	4.84e-06	185	104	6	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 FAM171A1 SLC9A3 CADM1 UGT8 SLC2A13	4.84e-06	185	104	6	898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SECISBP2L ERBB4 XKR6 MBIP CADM1 ATP8A1	4.99e-06	186	104	6	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	COPD-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	ERBB4 HIVEP2 MBIP CADM1 ATP8A1 RMC1	5.15e-06	187	104	6	030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCell	LV-14._Fibroblast_III\|World / Chamber and Cluster_Paper	HIVEP2 TTC3 EBF2 FAT1 KCND2 SLC2A13	5.47e-06	189	104	6	3922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCell	droplet-Limb_Muscle-nan-3m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADNP2 HOGA1 TMEM44 NECTIN2 PLSCR2 CARS2	5.47e-06	189	104	6	16a4c92dd7a0d60f3691bd3130a091a9a54730f1
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 SYNE1 FAM171A1 SLC9A3 CADM1 UGT8	5.47e-06	189	104	6	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B ERBB4 NEDD9 CADM1 UGT8 COL14A1	5.64e-06	190	104	6	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B ERBB4 NEDD9 CADM1 UGT8 COL14A1	5.64e-06	190	104	6	b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B ERBB4 NEDD9 CADM1 UGT8 COL14A1	5.81e-06	191	104	6	2fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 ERBB4 XKR6 UGT8 PLEKHA1 COL14A1	5.81e-06	191	104	6	5a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 ERBB4 XKR6 UGT8 PLEKHA1 COL14A1	5.81e-06	191	104	6	55ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCell	E15.5-Epithelial-alveolar_epithelial_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DPP4 MBIP NEDD9 CADM1 ATP8A1 ENPP5	5.99e-06	192	104	6	567f4355a01aae1f2eafc16fe86d1538a62030ab
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SECISBP2L ERBB4 SYNE1 MBIP CADM1 ATP8A1	6.17e-06	193	104	6	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SECISBP2L ERBB4 SYNE1 MBIP CADM1 ATP8A1	6.17e-06	193	104	6	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	LV-14._Fibroblast_III\|LV / Chamber and Cluster_Paper	HIVEP2 TTC3 EBF2 FAT1 KCND2 SLC2A13	6.35e-06	194	104	6	927c26aea0147f7a4b8fb3f192de4de263f1b978
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 FNDC3B DPP4 ERBB4 XKR6 PLEKHA1	6.54e-06	195	104	6	938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CCDC8 MXRA5 EBF3 FAT1 CADM1 RBFOX2	6.54e-06	195	104	6	ec12cfb2fce44cc2de4e198ef5af075e626f0329
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 FNDC3B DPP4 ERBB4 XKR6 PLEKHA1	6.54e-06	195	104	6	d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SECISBP2L ERBB4 MUC16 FAT1 SLC9A3 DTX2	6.54e-06	195	104	6	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SDK2 MXRA5 SYNE1 RBMS3 COL14A1 BSN	6.94e-06	197	104	6	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 IDS TTC3 KCND2 SLC2A13 RBFOX2	7.14e-06	198	104	6	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCC3 SH2B3 LILRB2 HLA-DRA SIGLEC11 SIGLEC1	7.35e-06	199	104	6	98c0d57c247d39bc771d81f4387f8dd01222628e
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCC3 SH2B3 LILRB2 HLA-DRA SIGLEC11 SIGLEC1	7.35e-06	199	104	6	b818d46a39c8782188d82dc8931b8eec9d549dd1
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FNDC3B SDK2 MXRA5 SYNE1 RBMS3 COL14A1	7.35e-06	199	104	6	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	10x3'2.3-week_12-13-Mesenchymal_fibro-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CCDC8 MXRA5 EBF3 EBF2 COL14A1 RBFOX2	7.56e-06	200	104	6	64d2941689d7ca8af54f9ba21c5aeabf719084ef
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EBF3 SYNE1 EBF2 KCND2 RBMS3 COL14A1	7.56e-06	200	104	6	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	10x3'2.3-week_12-13-Mesenchymal_fibro\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CCDC8 MXRA5 EBF3 EBF2 COL14A1 RBFOX2	7.56e-06	200	104	6	76f3043cb88071256ff661885fe5a82a54f5b733
ToppCell	severe_COVID-19-MAIT\|World / disease group, cell group and cell class (v2)	DPP4 TMEM185B LEMD3 WDR93 RBMS3	3.08e-05	154	104	5	65ec7f7ef05c589903c4c9fe3849478c325fdc61
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122\|Adult / Lineage, Cell type, age group and donor	SECISBP2L ERBB4 MBIP FAT1 ATP8A1	3.38e-05	157	104	5	31d1bd9138c60e8485664ec4144f987226e3eef9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 TMEM185B MEX3D SLC9A3 UGT8	3.59e-05	159	104	5	c186bf05c61fac348cf41973827cced83fafd58a
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FNDC3B EBF2 DTX4 COL14A1 PLXNA1	3.59e-05	159	104	5	7ed659163f45e0c4df4782997c0786900c8186c8
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SECISBP2L ERBB4 FAT1 CADM1 ATP8A1	3.59e-05	159	104	5	8680b054622f573a82b1625fb93c2d5db81d1034
ToppCell	Basal_cells-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	SDK2 MXRA5 FAM171A1 RBMS3 TP63	3.70e-05	160	104	5	b223cc47e68a29df4758c5ccf8f6dbffe2a6fa1d
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|356C / Donor, Lineage, Cell class and subclass (all cells)	CHST10 SH2B3 RESF1 ENPP5 ULK2	4.41e-05	166	104	5	c4f7ea1cad962b1d6ad77423d15978b68a0d6f1d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SECISBP2L ERBB4 MBIP CADM1 ATP8A1	4.41e-05	166	104	5	c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCell	Basal_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	SDK2 MXRA5 KCND2 TP63 COL14A1	4.94e-05	170	104	5	776d4224a682b6c648041827efd69794f88906f0
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231\|Adult / Lineage, Cell type, age group and donor	SECISBP2L ERBB4 MBIP FAT1 ATP8A1	4.94e-05	170	104	5	269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	CCDC8 MXRA5 MEX3D TP63 SIGLEC11	4.94e-05	170	104	5	aabe993c9f337b1caaeb0e64626a3920579c41b7
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SH2B3 HLA-DRA SI NECTIN2 PAK1	4.94e-05	170	104	5	7bba77ae34a0259fad6ee98cf665ff50f77a1328
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SH2B3 HLA-DRA SI NECTIN2 PAK1	4.94e-05	170	104	5	a43b977a7fe745536cf96b7c080397d9fa73086b
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CHST10 SH2B3 RESF1 ENPP5 ULK2	5.22e-05	172	104	5	a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCell	E17.5-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SECISBP2L DPP4 MBIP CADM1 ATP8A1	5.51e-05	174	104	5	68914ec843f58ecff3e6412544a341daf8a01cac
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW10-Neuronal-GABAergic_neurons\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	ERBB4 HOGA1 TP63 COL14A1 DHX34	5.66e-05	175	104	5	d4ff1f197ad4086286e86817cbff24fa718293fc
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-macrophage\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 CADM1 PAK1 SIGLEC1 PLXNA1	6.14e-05	178	104	5	6c1b5087581ca8cea976d89ea6f34088c8fc3668
ToppCell	CF-Myeloid-Neutrophil\|CF / Disease state, Lineage and Cell class	FNDC3B NEDD9 RESF1 PAK1 DHX34	7.00e-05	183	104	5	da43827952e6fdee2ce94648c316182f272b321c
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Adult / Lineage, Cell type, age group and donor	SECISBP2L ERBB4 MBIP FAT1 ATP8A1	7.37e-05	185	104	5	673f0c688ae6984bc8027df2da335787924f4137
ToppCell	systemic_lupus_erythematosus-flare-Hematopoietic-progenitor_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CCDC8 KIAA1549 WDR93 TMEM44 RBFOX2	7.56e-05	186	104	5	ffd4510b4435d9bf94c2ef14c629f73ab78c5d93
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Proliferative_AT2_Progenitor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	DPP4 CHST10 MBIP CADM1 ATP8A1	7.75e-05	187	104	5	e986901f5a1e09cbc9ba37e3c62845ff90ceda95
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 SLC9A3 CADM1 FAM222A UGT8	7.75e-05	187	104	5	85e58a312fc325e4063a2d250666b99b8f99beb6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 FAM171A1 SLC9A3 CADM1 SLC2A13	7.75e-05	187	104	5	b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 SLC9A3 CADM1 FAM222A UGT8	7.75e-05	187	104	5	52b5b38bef3cc06487cf42c6fb22fb33f0c7ce2b
ToppCell	E12.5-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DPP4 MBIP NEDD9 CADM1 ATP8A1	7.75e-05	187	104	5	baff4edc1bf64e3e03864a434fa47075ff7372fd
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	SECISBP2L ERBB4 MBIP CADM1 ATP8A1	7.75e-05	187	104	5	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DPP4 ERBB4 MBIP CADM1 ATP8A1	7.75e-05	187	104	5	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SECISBP2L SDK2 MBIP CADM1 ATP8A1	7.75e-05	187	104	5	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 FAM171A1 SLC9A3 CADM1 UGT8	7.95e-05	188	104	5	2ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCell	E12.5-Epithelial-alveolar_epithelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DPP4 MBIP NEDD9 CADM1 ATP8A1	7.95e-05	188	104	5	c19c89756f2f999e0814f08a89818ef156f6fc69
ToppCell	systemic_lupus_erythematosus-flare-Hematopoietic-progenitor_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CCDC8 KIAA1549 WDR93 TMEM44 RBFOX2	7.95e-05	188	104	5	c613c6c7b6de8ed514253c9f9b8622c56fcc1452
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	DPP4 ERBB4 MBIP CADM1 ATP8A1	8.15e-05	189	104	5	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 DPP4 KIAA1549 ATP8A1 PLXNA1	8.15e-05	189	104	5	09dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 XKR6 FAM171A1 CADM1 ATP8A1	8.15e-05	189	104	5	977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 FNDC3B DPP4 ERBB4 PLEKHA1	8.15e-05	189	104	5	aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCell	COPD-Epithelial-ATI\|Epithelial / Disease state, Lineage and Cell class	FLNA NEDD9 CADM1 RBMS3 PLXNA1	8.15e-05	189	104	5	14e8e57e4db336fbef005270647983b4edf407c0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 FNDC3B DPP4 ERBB4 PLEKHA1	8.15e-05	189	104	5	8977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	EBF3 EBF2 KCND2 RBMS3 COL14A1	8.35e-05	190	104	5	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DPP4 ERBB4 MBIP CADM1 ATP8A1	8.35e-05	190	104	5	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 ERBB4 SYNE1 UGT8 PLEKHA1	8.35e-05	190	104	5	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B DPP4 UGT8 PLEKHA1 SLC2A13	8.35e-05	190	104	5	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 FAM171A1 SLC9A3 CADM1 UGT8	8.35e-05	190	104	5	3dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 XKR6 FAM171A1 CADM1 ATP8A1	8.35e-05	190	104	5	e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC8 ERBB4 SLC9A3 CADM1 UGT8	8.56e-05	191	104	5	f631749ef1f2270133664cf5eb4cf545a8482bd3
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SECISBP2L DPP4 MBIP CADM1 ATP8A1	8.56e-05	191	104	5	08b1d3b3be78bf7fd9e9039027e35275f2be88d0
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SECISBP2L DPP4 MBIP CADM1 ATP8A1	8.56e-05	191	104	5	f896fb490c4a17adac5e00ed9b6e6145eab1e564
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SECISBP2L ERBB4 MBIP CADM1 ATP8A1	8.56e-05	191	104	5	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	DPP4 ERBB4 MBIP CADM1 ATP8A1	8.56e-05	191	104	5	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	SECISBP2L ERBB4 MBIP CADM1 ATP8A1	8.56e-05	191	104	5	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 FNDC3B ERBB4 CADM1 PLEKHA1	8.56e-05	191	104	5	9032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCell	RV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	FNDC3B EBF2 EYS RBMS3 SLC2A13	8.56e-05	191	104	5	70c067c54084bfb02c29bab085f4defd477194fb
ToppCell	(1)_Osterolineage_cells-(10)_OLC-1\|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis	EBF3 FAT1 CADM1 RESF1 ENPP5	8.56e-05	191	104	5	78ad7c555409ce1391bce406bc0f3ef575329ece
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 FNDC3B ERBB4 CADM1 PLEKHA1	8.56e-05	191	104	5	5717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 FAM171A1 SLC9A3 CADM1 UGT8	8.77e-05	192	104	5	562df5e87038c500dd3a003fe5374cb31946b145
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DPP4 ERBB4 MBIP CADM1 ATP8A1	8.77e-05	192	104	5	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	E18.5-Epithelial\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SECISBP2L DPP4 MBIP CADM1 ATP8A1	8.77e-05	192	104	5	75bc06ce38478f06ba29a2cc3d238aa26e87a951
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SECISBP2L FAM171A1 ATP8A1 DTX4 UGT8	8.77e-05	192	104	5	8dc3016601148243196e925641c9507e9d58c9e0
ToppCell	E18.5-Epithelial-Epithelial_Alveolar\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SECISBP2L DPP4 MBIP CADM1 ATP8A1	8.99e-05	193	104	5	8e750a2b198ad6840a6842a7ddd93623faf7c656
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 FNDC3B ERBB4 SYNE1 PLEKHA1	8.99e-05	193	104	5	f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SECISBP2L DPP4 MBIP CADM1 ATP8A1	8.99e-05	193	104	5	6cc09f20dd119236c3c9968f3d16c3eabc0811e2
ToppCell	LA-14._Fibroblast_III\|LA / Chamber and Cluster_Paper	HIVEP2 EBF2 KCND2 RBMS3 SLC2A13	8.99e-05	193	104	5	7426c291bac59e539c427bcaae18abc7d397d44e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 FNDC3B ERBB4 SYNE1 PLEKHA1	8.99e-05	193	104	5	42df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SECISBP2L FAM171A1 ATP8A1 FAM222A UGT8	9.21e-05	194	104	5	cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MXRA5 HLA-DRA KIAA1549 FAT1 CADM1	9.21e-05	194	104	5	4579b4a44f7c731553a284843c296866027d7c0e
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SH2B3 LILRB2 HLA-DRA SIGLEC11 SIGLEC1	9.21e-05	194	104	5	8e2819a9d0529f7b2de1a7c1190575175d6173ee
Disease	serum alanine aminotransferase measurement	FNDC3B SH2B3 BCORL1 HECTD4 APOB XKR6 RESF1 RBMS3 ZNF341 NECTIN2 ELF1 RMC1 CARS2 RBFOX2	2.02e-06	869	103	14	EFO_0004735
Disease	ovarian neoplasm	PMS2 MUC16 MSH2 BABAM1 TP63 NECTIN2	7.81e-06	134	103	6	C0919267
Disease	Malignant neoplasm of ovary	PMS2 MUC16 MSH2 BABAM1 TP63 NECTIN2	8.87e-06	137	103	6	C1140680
Disease	cervix uteri carcinoma in situ (is_marker_for)	MSH2 CADM1 TP63 TP73	1.42e-05	42	103	4	DOID:8991 (is_marker_for)
Disease	Proteinuria	DPP4 MUC16 GUSB PAK1	1.56e-05	43	103	4	C0033687
Disease	esophagus squamous cell carcinoma (is_implicated_in)	ERBB4 MSH2 FAT1 COL14A1	1.87e-05	45	103	4	DOID:3748 (is_implicated_in)
Disease	Malignant neoplasm of breast	FNDC3B FLNA ERBB4 NOA1 SYNE1 BCORL1 MTMR8 TTC3 NCOR1 CADM1 NECTIN2 PAK1 CYB5R4 TP73	2.22e-05	1074	103	14	C0006142
Disease	neuroticism measurement, cognitive function measurement	DPP4 ERBB4 SH2B3 NUP210L R3HDM2 XKR6 NEDD9 CADM1 PLEKHA1 RMC1	2.98e-05	566	103	10	EFO_0007660, EFO_0008354
Disease	body weight	SECISBP2L ERBB4 HIVEP2 HECTD4 EBF2 NCOR1 EYS CADM1 RBMS3 ZNF341 GUSB UGT8 PLEKHA1 RMC1 PLXNA1	3.19e-05	1261	103	15	EFO_0004338
Disease	factor VIII measurement, Ischemic stroke	STAB2 SH2B3 HECTD4	3.84e-05	19	103	3	EFO_0004630, HP_0002140
Disease	visceral adipose tissue measurement	ERBB4 HIVEP2 EBF2 TSBP1 NECTIN2 COL14A1 SIGLEC1 RMC1 TP73	4.88e-05	481	103	9	EFO_0004765
Disease	colorectal cancer (is_implicated_in)	ERBB4 SH2B3 MSH2 FAT1 TP73	6.78e-05	121	103	5	DOID:9256 (is_implicated_in)
Disease	Constitutional Mismatch Repair Deficiency Syndrome	PMS2 MSH2	7.21e-05	4	103	2	C4321324
Disease	hepatitis C induced liver cirrhosis	HLA-DRA TSBP1	7.21e-05	4	103	2	EFO_0005129
Disease	Turcot syndrome	PMS2 MSH2	7.21e-05	4	103	2	cv:C0265325
Disease	Lynch syndrome	PMS2 MSH2	7.21e-05	4	103	2	cv:C4552100
Disease	cystatin C measurement	ERBB4 HIVEP2 SH2B3 HECTD4 R3HDM2 EBF2 NECTIN2 BSN	8.53e-05	402	103	8	EFO_0004617
Disease	testicular cancer (implicated_via_orthology)	TP63 TP73	1.20e-04	5	103	2	DOID:2998 (implicated_via_orthology)
Disease	Turcot syndrome (disorder)	PMS2 MSH2	1.20e-04	5	103	2	C0265325
Disease	Ischemic stroke, von Willebrand factor measurement	STAB2 SH2B3 HECTD4	1.57e-04	30	103	3	EFO_0004629, HP_0002140
Disease	Breast Cancer, Familial	PMS2 MCPH1 MSH2	1.57e-04	30	103	3	C0346153
Disease	Adenoid Cystic Carcinoma	BCORL1 FAT1 DTX4 RBFOX2	4.25e-04	100	103	4	C0010606
Disease	Lynch Syndrome	PMS2 MSH2	4.28e-04	9	103	2	C4552100
Disease	systemic lupus erythematosus	ERBB4 HLA-DOB HLA-DRA HECTD4 XKR6 FAM171A1 TSBP1 TP63 ELF1 NEURL4	4.90e-04	799	103	10	MONDO_0007915
Disease	urinary bladder cancer (is_marker_for)	ERBB4 MSH2 TP63 TP73	5.48e-04	107	103	4	DOID:11054 (is_marker_for)
Disease	Breast Carcinoma	FLNA ERBB4 SYNE1 NCOR1 CADM1 NECTIN2 PAK1 TP73	6.06e-04	538	103	8	C0678222
Disease	forced expiratory volume, body mass index	SH2B3 HECTD4	6.50e-04	11	103	2	EFO_0004314, EFO_0004340
Disease	factor VIII measurement, coronary artery disease	STAB2 HLA-DOB APOB TSBP1	6.73e-04	113	103	4	EFO_0001645, EFO_0004630
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	LEMD3 SYNE1	7.78e-04	12	103	2	DOID:11726 (implicated_via_orthology)
Disease	mismatch repair cancer syndrome (is_implicated_in)	PMS2 MSH2	7.78e-04	12	103	2	DOID:0112182 (is_implicated_in)
Disease	Colorectal Carcinoma	ABCC3 PMS2 SYNE1 APOB MSH2 FAT1 TP63 PKNOX1 AGTPBP1	7.98e-04	702	103	9	C0009402
Disease	complement C4 measurement	HLA-DOB HLA-DRA TSBP1	8.06e-04	52	103	3	EFO_0004984
Disease	hematocrit	HIVEP2 SH2B3 BCORL1 HECTD4 R3HDM2 APOB FAT1 SAG RBMS3 UGT8 BSN	8.16e-04	1011	103	11	EFO_0004348
Disease	glycoprotein measurement	HLA-DRA R3HDM2 APOB XKR6	8.17e-04	119	103	4	EFO_0004555
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	R3HDM2 APOB XKR6 NECTIN2	8.70e-04	121	103	4	EFO_0008595, EFO_0020943
Disease	rheumatoid arthritis, smoking status measurement, ACPA-positive rheumatoid arthritis	HLA-DOB HLA-DRA	9.18e-04	13	103	2	EFO_0000685, EFO_0006527, EFO_0009459
Disease	homostachydrine measurement	ERBB4 EYS	9.18e-04	13	103	2	EFO_0021164
Disease	ovarian cancer (is_implicated_in)	PMS2 MUC16 APOB	1.00e-03	56	103	3	DOID:2394 (is_implicated_in)
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	R3HDM2 APOB XKR6 NECTIN2	1.04e-03	127	103	4	EFO_0008595, EFO_0020947
Disease	systolic blood pressure, alcohol drinking	SH2B3 HECTD4 XKR6 EYS	1.07e-03	128	103	4	EFO_0004329, EFO_0006335
Disease	Ischemic stroke, tissue plasminogen activator measurement	SH2B3 HECTD4	1.23e-03	15	103	2	EFO_0004791, HP_0002140
Disease	Alzheimer disease, peptic ulcer disease, Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement, gastroesophageal reflux disease	HLA-DRA NECTIN2	1.23e-03	15	103	2	EFO_0003948, EFO_0009923, MONDO_0004247, MONDO_0004975
Disease	response to opioid	MUC16 MSH2 TP63	1.28e-03	61	103	3	EFO_0008541
Disease	age at diagnosis, type 1 diabetes mellitus	HLA-DRA EYS TSBP1	1.35e-03	62	103	3	EFO_0004918, MONDO_0005147
Disease	Ischemic stroke, plasminogen activator inhibitor 1 measurement	SH2B3 HECTD4	1.40e-03	16	103	2	EFO_0004792, HP_0002140
Disease	transitional cell carcinoma (is_marker_for)	ERBB4 PAK1 TP73	1.41e-03	63	103	3	DOID:2671 (is_marker_for)
Disease	coronary artery disease, plasminogen activator inhibitor 1 measurement	SH2B3 APOB NECTIN2	1.41e-03	63	103	3	EFO_0001645, EFO_0004792
Disease	sarcoidosis	HLA-DOB HLA-DRA TSBP1	1.47e-03	64	103	3	MONDO_0019338
Disease	lung carcinoma	SECISBP2L HLA-DOB HLA-DRA RBMS3 TP63 SIGLEC11 TP73	1.53e-03	482	103	7	EFO_0001071
Disease	Alzheimer disease	LILRB2 UFC1 RBMS3 NECTIN2 PLEKHA1 SIGLEC11 SLC2A13	1.58e-03	485	103	7	MONDO_0004975
Disease	factor XI measurement, Ischemic stroke	SH2B3 HECTD4	1.59e-03	17	103	2	EFO_0004694, HP_0002140
Disease	parental longevity	ERBB4 SH2B3 HLA-DRA HECTD4 RBMS3 BSN RBFOX2	1.76e-03	494	103	7	EFO_0007796
Disease	Malignant neoplasm of endometrium	PMS2 MSH2	1.78e-03	18	103	2	C0007103
Disease	Carcinoma in situ of endometrium	PMS2 MSH2	1.78e-03	18	103	2	C0346191
Disease	breast cancer (is_implicated_in)	MCPH1 MSH2 PAK1 TP73	1.92e-03	150	103	4	DOID:1612 (is_implicated_in)
Disease	laryngeal squamous cell carcinoma (is_marker_for)	ERBB4 MSH2	1.99e-03	19	103	2	DOID:2876 (is_marker_for)
Disease	tissue plasminogen activator measurement, coronary artery disease	SH2B3 HLA-DOB APOB	1.99e-03	71	103	3	EFO_0001645, EFO_0004791
Disease	major depressive disorder	ERBB4 HIVEP2 RBMS3 BSN	2.16e-03	155	103	4	MONDO_0002009
Disease	prostate cancer (is_marker_for)	ERBB4 PMS2 MSH2 TP73	2.21e-03	156	103	4	DOID:10283 (is_marker_for)
Disease	lung cancer (is_implicated_in)	MSH2 TP63 TP73	2.24e-03	74	103	3	DOID:1324 (is_implicated_in)
Disease	esophagus squamous cell carcinoma (is_marker_for)	DPP4 ERBB4 FAT1	2.24e-03	74	103	3	DOID:3748 (is_marker_for)
Disease	Autoimmune Hepatitis	SH2B3 TSBP1	2.43e-03	21	103	2	EFO_0005676
Disease	Mammary Carcinoma, Human	FLNA SYNE1 NCOR1 CADM1 NECTIN2 PAK1 TP73	2.47e-03	525	103	7	C4704874
Disease	Mammary Neoplasms, Human	FLNA SYNE1 NCOR1 CADM1 NECTIN2 PAK1 TP73	2.47e-03	525	103	7	C1257931
Disease	Mammary Neoplasms	FLNA SYNE1 NCOR1 CADM1 NECTIN2 PAK1 TP73	2.53e-03	527	103	7	C1458155
Disease	transitional cell carcinoma (is_implicated_in)	MSH2 TP63	2.66e-03	22	103	2	DOID:2671 (is_implicated_in)
Disease	susceptibility to scarlet fever measurement	SDK2 HLA-DOB HLA-DRA	2.69e-03	79	103	3	EFO_0008409
Disease	Carcinoma of lung	MXRA5 TP63	2.91e-03	23	103	2	C0684249
Disease	Colorectal Neoplasms	ABCC3 SYNE1 MSH2 FAT1 TP63	2.91e-03	277	103	5	C0009404
Disease	Charcot-Marie-Tooth disease (implicated_via_orthology)	MTMR8 AARS2	3.17e-03	24	103	2	DOID:10595 (implicated_via_orthology)
Disease	Dyslipidemias	APOB NECTIN2	3.17e-03	24	103	2	C0242339
Disease	Dyslipoproteinemias	APOB NECTIN2	3.17e-03	24	103	2	C0598784
Disease	Lynch syndrome (is_implicated_in)	PMS2 MSH2	3.17e-03	24	103	2	DOID:3883 (is_implicated_in)
Disease	autoimmune disease	SH2B3 TSBP1 PLEKHA1 NEURL4	3.21e-03	173	103	4	EFO_0005140
Disease	C-reactive protein measurement	ZSWIM8 ERBB4 NUP210L HLA-DRA R3HDM2 APOB XKR6 NCOR1 NECTIN2 BSN RMC1	3.27e-03	1206	103	11	EFO_0004458
Disease	Cancer of Neck	FAT1 TP63	3.44e-03	25	103	2	C0746787
Disease	FEV change measurement, response to zileuton	SDK2 RBMS3	3.44e-03	25	103	2	EFO_0005921, EFO_0007676

Protein segments in the cluster

Peptide	Gene	Start	Entry
PSQSPAPVQVYIRRG	C2orf16	1221	Q68DN1
VQVGIAPYPVPSTLG	FAM222A	141	Q5U5X8
GVSVPYRAPTSTIPE	ERBB4	1076	Q15303
EVLRTVQPTQSPYPT	ELF1	366	P32519
VYQVPPSVQRSIGGT	NEDD9	131	Q14511
STIPGTYVGVANPVP	BCORL1	711	Q5H9F3
PPRHIPGVVEVTLSY	EBF2	306	Q9HAK2
RVQVYPPVGAASTPT	SAG	91	P10523
IRIIYSIPPGIQGPE	DTX4	501	Q9Y2E6
VIPVTGPVAQLYSLP	AGTPBP1	346	Q9UPW5
NYVRVGTTRVPLTGP	ATP2A1	526	O14983
RVLTYTIPISNPLGP	GRAMD1A	421	Q96CP6
PDVSPTGRYTTLVPL	ATP8A1	91	Q9Y2Q0
GIPTYTLAPVSVTLP	ADNP2	611	Q6IQ32
TPPSTRFPGVAIYLV	POLM	21	Q9NP87
VVQYTPLPSYQVPVG	R3HDM2	601	Q9Y2K5
PQVSPRVTYTRVSPG	TP53I13	46	Q8NBR0
QYTPVPPTAVSIEGV	RBMS3	381	Q6XE24
TVYGAVRAVPPTAIP	RBFOX2	291	O43251
PAPVFFVTPLVVGVT	ABCC3	101	O15438
GIVPTPGRNLVLYPT	KIAA1549	241	Q9HCM3
LSPGPVTESTRPVYL	LEMD3	26	Q9Y2U8
IYSDIPPQVPVRPIS	FAT1	4241	Q14517
PGTQTGFTVPIRTVP	MUC16	11666	Q8WXI7
VYRVSVPENLPVGTP	PCDHGA6	246	Q9Y5G7
TPVLVDGPIYVTVPL	FAM171A1	216	Q5VUB5
SPIPVVLYSVPANTG	HOGA1	161	Q86XE5
VSQVPRQASIVIGPY	MCPH1	786	Q8NEM0
FTPITIRYTTPVGSP	EYS	2236	Q5T1H1
YPPEIVVPKSVTLGT	MTMR8	161	Q96EF0
SVRRQAGPPYPVTTI	DTX2	171	Q86UW9
GPTAISPYLPGIQIV	BSN	2736	Q9UPA5
IEIQAPPGVPVGYVT	PLSCR2	181	Q9NRY7
PSTQIYVPVGVVKPI	PLXNA1	711	Q9UIW2
YVVVPPTLNPVIYGV	OR52E6	281	Q96RD3
VLPYRVFVPLPGSTV	ODR4	341	Q5SWX8
VVPYTQSTILLPGSV	ENPP5	406	Q9UJA9
PGQTTIQVRVPYRVV	MEX3D	271	Q86XN8
PYVTTAIISIPTPPV	KCND2	591	Q9NZV8
IRGTPFISVQPGPTV	LILRB2	321	Q8N423
YVLTQPPSVSVAPGQ	IGLV3-21	21	P80748
TVRVPYPKAGAVNPT	DPP4	251	P27487
PRGTFIYATSPLPVQ	HECTD4	1976	Q9Y4D8
YTRSVIEPLPVTPTR	PAK1	201	Q13153
TGRQSVVVPYEPPQV	TP73	231	O15350
TGRQSVLVPYEPPQV	TP63	281	Q9H3D4
PQESYTTITVLVPPR	CADM1	131	Q9BY67
ELPRTFQIPGYTVPV	APOB	3241	P04114
LPVTENVQTIPPPYV	BABAM1	196	Q9NWV8
VQPEVTVYPERTPLL	HLA-DOB	121	P13765
AGVPIPRSPYTVTVG	FLNA	461	P21333
IVYKPVSVPGPTLET	COL14A1	861	Q05707
VRRVVVTPQSPECYP	FNDC3B	96	Q53EP0
LTPTTLPPGTIQYLT	GUSB	176	P08236
PRPTLPNVVYVGGIL	UGT8	251	Q16880
RSNYTPITNVPPEVT	HLA-DRA	101	P01903
VVNTYGPQTRPEGIP	MBIP	216	Q9NS73
GVPPVPTQYPITQVQ	KHDC4	401	Q7Z7F0
VQALNISVPYGPIPV	IDS	276	P22304
PPRHIPGVVEVTLSY	EBF3	316	Q9H4W6
VTPPPRLVVGTYDSS	CCDC8	86	Q9H0W5
VPGRLFPITVVYQPQ	DHX34	331	Q14147
GPPGVPIIVRYSSAI	SDK2	1826	Q58EX2
VTPLGVPVIQPYRLD	POLRMT	1071	O00411
VSNGAPVPYVRPAIL	MSH2	611	P43246
GVATPLTPPVVYGVV	NEURL4	456	Q96JN8
YTPEGTVLTVRPPLL	NOA1	646	Q8NC60
TVPVVYVPTLGTPQP	NUP210L	1841	Q5VU65
VVVPPALNPVIYGVR	OR52E8	286	Q6IFG1
PVTQKPVTTVTRTYP	MUC3B	161	Q9H195
TVPVYIAEVSPPNLR	SLC2A13	191	Q96QE2
VLPPTVYLRVTENIP	CARS2	156	Q9HA77
IYRTRSVNGIPVPPD	SYNE1	466	Q8NF91
ARVVITQSPGKYVPP	TMEM185B	326	Q9H7F4
VAGGTVYQPVTVVTP	PKNOX1	206	P55347
PTPSPAPQQYIVVTV	RFX1	91	P22670
VKGITPAVLPETVYP	RESF1	776	Q9HCM1
DRITYIPGTQITFPP	NCOR1	1676	O75376
VVPSQRARTQIPYSP	SLC9A3	781	P48764
SVSGVEPTPIPSYLI	SECISBP2L	41	Q93073
IQPTPIVTYRVTGGI	SI	306	P14410
RYEVPVPLNIPTTPI	SI	1041	P14410
PITGTEIVKPYTPVS	CYB5R4	316	Q7L1T6
VYPDPVRVVSVGVPV	AARS2	716	Q5JTZ9
PTIPPGITVYNRTKV	CHST10	306	O43529
IPITYPTTAPEIAVP	UFC1	86	Q9Y3C8
PEIPGYRGTQVTPTR	XKR6	531	Q5GH73
TYITVPPSPLIQTLV	ZNF341	116	Q9BYN7
SIQPYQIPITGPAAV	RMC1	311	Q96DM3
LFTTSPLVVQYVPRP	TRIM51	391	Q9BSJ1
PLVVQYVPRPTSTVG	TRIM51	396	Q9BSJ1
SPEYQLPRSVPVVPS	TTC3	1356	P53804
VRLSSYVVVVSQPPG	SH2B3	456	Q9UQQ2
YTLTGVLIPPSIVPI	STAB2	646	Q8WWQ8
PSYPPVQVIRARVSS	TMEM44	411	Q2T9K0
VLTVLYPPRQPTFTT	SIGLEC1	591	Q9BZZ2
KTPYPRPRGTTVSVQ	PMS2	146	P54278
SETAPIPVPTQIRNY	ULK2	396	Q8IYT8
VVPVISVGSSLYPGP	ZSWIM8	1481	A7E2V4
NPSVYVPGVVSTVVP	U2AF2	241	P26368
SSQIQPTVYPPLGEI	WDR93	86	Q6P2C0
PVLVVPYPILASGET	ZNF362	206	Q5T0B9
YRTDIVGGVPIITPT	PLEKHA1	141	Q9HB21
GTVVPVRIQTHVPSY	HIVEP2	1331	P31629
TIVQTPGPIVQYPGS	TSBP1	156	Q5SRN2
VYIPETLEPGQPVTV	SIGLEC11	161	Q96RL6
VTSIPVIVIAYPPRI	MXRA5	2721	Q9NR99
VIVIAYPPRITSEPT	MXRA5	2726	Q9NR99
IPVTLSVRYPPEVSI	NECTIN2	251	Q92692