Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	DOCK4 DENND2A DENND4A DENND2B PLCG1 HERC1 PSD2 ARFGEF2 ARHGEF18 DOCK7 ARHGEF2 RAPGEF2	1.08e-05	231	221	12	GO:0005085
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH5 DNAH8 DNHD1 DNAH17	3.96e-05	18	221	4	GO:0008569
GeneOntologyMolecularFunction	ATP hydrolysis activity	ATP6V1A DDX19A ERCC6 ERCC6L TOR1B CARNS1 DNAH5 DNAH8 DHX37 SMCHD1 RNF213 CCT4 CHD7 CHTF18 ATP2A1	1.25e-04	441	221	15	GO:0016887
GeneOntologyMolecularFunction	glutamate receptor activity	PTK2B GRIK3 GRIK5 GRM3	2.10e-04	27	221	4	GO:0008066
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH5 DNAH8 DNHD1 DNAH17	2.43e-04	28	221	4	GO:0051959
GeneOntologyMolecularFunction	enzyme regulator activity	RABEP2 RALGAPA1 DOCK4 DENND2A DENND4A ERCC4 ERCC6 PDE8A WDR4 BCAS3 PSMD3 DENND2B SIMC1 PLCG1 HERC1 BSN ALK PSD2 DBF4B ARFGEF2 ARHGEF18 ATG14 THBS1 PPP2R5B DOCK7 MOB3C ARHGEF2 RAPGEF2 PPP1R16A PHACTR1	4.73e-04	1418	221	30	GO:0030234
GeneOntologyMolecularFunction	ATP-dependent activity	ATP6V1A DDX19A ERCC6 ERCC6L TOR1B CARNS1 DNAH5 DNAH8 DNHD1 DHX37 SMCHD1 RNF213 CCT4 CHD7 CHTF18 DNAH17 ATP2A1	5.08e-04	614	221	17	GO:0140657
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	KCNA4 SLC12A6 GRIK3 GRIK5 TMEM87A KCNH4 KCNIP4 MCOLN3	5.57e-04	167	221	8	GO:0015079
GeneOntologyMolecularFunction	potassium channel activity	KCNA4 GRIK3 GRIK5 TMEM87A KCNH4 KCNIP4 MCOLN3	5.64e-04	128	221	7	GO:0005267
GeneOntologyMolecularFunction	GTPase binding	DOCK4 LZTR1 DIAPH1 WASF1 FMNL1 FLNA XPO4 AMBRA1 ATG14 FMNL3 DOCK7 ARHGEF2	7.09e-04	360	221	12	GO:0051020
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH5 DNAH8 DNHD1 DNAH17	7.24e-04	37	221	4	GO:0045505
GeneOntologyMolecularFunction	glutamate-gated receptor activity	PTK2B GRIK3 GRIK5	8.11e-04	17	221	3	GO:0004970
GeneOntologyCellularComponent	axoneme	CFAP54 DNAH5 DNAH8 BRWD1 DNHD1 RPGRIP1 ARFGEF2 AMBRA1 ATG14 AK8 DNAH17	1.66e-05	207	226	11	GO:0005930
GeneOntologyCellularComponent	ciliary plasm	CFAP54 DNAH5 DNAH8 BRWD1 DNHD1 RPGRIP1 ARFGEF2 AMBRA1 ATG14 AK8 DNAH17	1.73e-05	208	226	11	GO:0097014
GeneOntologyCellularComponent	cytoplasmic region	CFAP54 BSN DNAH5 DNAH8 BRWD1 NLRP5 DNHD1 RPGRIP1 ARFGEF2 AMBRA1 ATG14 GRIK3 AK8 DNAH17	4.03e-05	360	226	14	GO:0099568
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	CFAP54 BSN DNAH5 DNAH8 BRWD1 DNHD1 RPGRIP1 ARFGEF2 AMBRA1 ATG14 GRIK3 AK8 DNAH17	4.43e-05	317	226	13	GO:0032838
GeneOntologyCellularComponent	cell body	TRPM4 GAD2 NDN GDPD5 PTK2B PTPN13 SYT11 DHODH KLHL14 BSN ALK FLNA FLNB PSD2 PUM2 CCT4 GRIK3 GRIK5 RLBP1 STEEP1 KCNIP4 ARHGEF2 RAPGEF2 PRPH	7.36e-05	929	226	24	GO:0044297
GeneOntologyCellularComponent	endoplasmic reticulum exit site	CTAGE4 CTAGE6 SEC24C CTAGE8 CTAGE15	8.68e-05	42	226	5	GO:0070971
GeneOntologyCellularComponent	axonemal dynein complex	DNAH5 DNAH8 DNHD1 DNAH17	1.41e-04	25	226	4	GO:0005858
GeneOntologyCellularComponent	outer dynein arm	DNAH5 DNAH8 DNAH17	2.55e-04	12	226	3	GO:0036157
GeneOntologyCellularComponent	cilium	RABEP2 QRICH2 CFAP54 USH1G DNAH5 DNAH8 UBXN10 BRWD1 DNHD1 RPGRIP1 TCP11 ARFGEF2 AMBRA1 ATG14 CCT4 AK8 MROH2B DNAH17 CEP83 SEPTIN12 PRPH	7.78e-04	898	226	21	GO:0005929
HumanPheno	Abnormal sperm morphology	ACR QRICH2 AURKC DNAH8 BRWD1 DNHD1 DNAH17 SEPTIN12	1.03e-05	66	84	8	HP:0012864
HumanPheno	Large face	ERCC4 ERCC6 BCAS3 GFPT1 TAF1 HERC1 SLC12A6 FLNA FLNB HUWE1 CHAMP1 JMJD1C SEC24C ARVCF STEEP1 ASXL2	1.11e-05	283	84	16	HP:0100729
HumanPheno	Abnormal germ cell morphology	ACR QRICH2 AURKC DNAH8 BRWD1 DNHD1 DNAH17 SEPTIN12	1.16e-05	67	84	8	HP:0012862
HumanPheno	Abnormal male germ cell morphology	ACR QRICH2 AURKC DNAH8 BRWD1 DNHD1 DNAH17 SEPTIN12	1.16e-05	67	84	8	HP:0012863
HumanPheno	Choanal atresia	ERCC4 PTPN14 DHODH SMCHD1 POLR1C CHD7 JMJD1C SEC24C ARVCF DCHS1	2.85e-05	123	84	10	HP:0000453
HumanPheno	Choanal atresia or stenosis	ERCC4 PTPN14 DHODH SMCHD1 POLR1C CHD7 JMJD1C SEC24C ARVCF DCHS1	5.97e-05	134	84	10	HP:0000416
HumanPheno	Abnormal choanae morphology	ERCC4 PTPN14 DHODH SMCHD1 POLR1C CHD7 JMJD1C SEC24C ARVCF DCHS1	5.97e-05	134	84	10	HP:0000415
HumanPheno	Abnormal sperm tail morphology	QRICH2 AURKC DNAH8 BRWD1 DNHD1 DNAH17	6.28e-05	43	84	6	HP:0012868
HumanPheno	Long face	ERCC4 ERCC6 BCAS3 GFPT1 TAF1 HERC1 SLC12A6 HUWE1 CHAMP1 JMJD1C SEC24C ARVCF STEEP1 ASXL2	6.98e-05	259	84	14	HP:0000276
HumanPheno	Absent sperm flagella	QRICH2 DNAH8 BRWD1 DNHD1 DNAH17	7.89e-05	28	84	5	HP:0032558
HumanPheno	Malar flattening	ATP6V1A DHODH HERC1 FLNA FLNB COL11A2 POLR1C CHD7 JMJD1C BUD23 SEC24C ARVCF DCHS1	1.28e-04	240	84	13	HP:0000272
HumanPheno	Platybasia	FLNB JMJD1C SEC24C ARVCF	1.39e-04	17	84	4	HP:0002691
HumanPheno	Patellar dislocation	FLNA FLNB ARFGEF2 JMJD1C BUD23 SEC24C ARVCF	1.46e-04	71	84	7	HP:0002999
HumanPheno	Short sperm flagella	QRICH2 DNAH8 BRWD1 DNHD1 DNAH17	1.79e-04	33	84	5	HP:0032559
HumanPheno	Abnormal malar bone morphology	ATP6V1A DHODH HERC1 FLNA FLNB COL11A2 POLR1C CHD7 JMJD1C BUD23 SEC24C ARVCF DCHS1	1.85e-04	249	84	13	HP:0012369
HumanPheno	Abnormal zygomatic arch morphology	ATP6V1A DHODH HERC1 FLNA FLNB COL11A2 POLR1C CHD7 JMJD1C BUD23 SEC24C ARVCF DCHS1	1.93e-04	250	84	13	HP:0005557
HumanPheno	Abnormal zygomatic bone morphology	ATP6V1A DHODH HERC1 FLNA FLNB COL11A2 POLR1C CHD7 JMJD1C BUD23 SEC24C ARVCF DCHS1	1.93e-04	250	84	13	HP:0010668
HumanPheno	Accessory carpal bones	FLNA FLNB	2.69e-04	2	84	2	HP:0004232
HumanPheno	Flat sella turcica	ALDH18A1 FLNA	2.69e-04	2	84	2	HP:0100857
HumanPheno	Bipartite calcaneus	FLNA FLNB	2.69e-04	2	84	2	HP:0008127
Domain	ARM-type_fold	RALGAPA1 INTS1 PIK3CG DIAPH1 FMNL1 ARMC6 ARFGEF2 XPO4 PUM2 NBEA ZYG11B FRYL HUWE1 CWC22 WDFY4 FMNL3 ELMO3 PPP2R5B ARVCF MROH2B LTN1	3.80e-10	339	214	21	IPR016024
Domain	ARM-like	ARMC6 ARFGEF2 XPO4 PUM2 NBEA ZYG11B FRYL HUWE1 WDFY4 ELMO3 ARVCF MROH2B LTN1	1.49e-05	270	214	13	IPR011989
Domain	Drf_GBD	DIAPH1 FMNL1 FMNL3	1.18e-04	9	214	3	PF06371
Domain	Drf_FH3	DIAPH1 FMNL1 FMNL3	1.18e-04	9	214	3	PF06367
Domain	FH3_dom	DIAPH1 FMNL1 FMNL3	1.18e-04	9	214	3	IPR010472
Domain	GTPase-bd	DIAPH1 FMNL1 FMNL3	1.18e-04	9	214	3	IPR010473
Domain	Drf_FH3	DIAPH1 FMNL1 FMNL3	1.18e-04	9	214	3	SM01139
Domain	Drf_GBD	DIAPH1 FMNL1 FMNL3	1.18e-04	9	214	3	SM01140
Domain	FERM_M	PTK2B PTPN13 PTPN14 PLEKHH2 FRMPD2	1.76e-04	46	214	5	PF00373
Domain	GBD/FH3_dom	DIAPH1 FMNL1 FMNL3	2.29e-04	11	214	3	IPR014768
Domain	GBD_FH3	DIAPH1 FMNL1 FMNL3	2.29e-04	11	214	3	PS51232
Domain	-	PTK2B PTPN13 PTPN14 PLEKHH2 FRMPD2	2.38e-04	49	214	5	1.20.80.10
Domain	FERM_central	PTK2B PTPN13 PTPN14 PLEKHH2 FRMPD2	2.38e-04	49	214	5	IPR019748
Domain	FERM_domain	PTK2B PTPN13 PTPN14 PLEKHH2 FRMPD2	2.38e-04	49	214	5	IPR000299
Domain	FERM/acyl-CoA-bd_prot_3-hlx	PTK2B PTPN13 PTPN14 PLEKHH2 FRMPD2	2.63e-04	50	214	5	IPR014352
Domain	FERM_1	PTK2B PTPN13 PTPN14 PLEKHH2 FRMPD2	2.63e-04	50	214	5	PS00660
Domain	FERM_2	PTK2B PTPN13 PTPN14 PLEKHH2 FRMPD2	2.63e-04	50	214	5	PS00661
Domain	FERM_3	PTK2B PTPN13 PTPN14 PLEKHH2 FRMPD2	2.63e-04	50	214	5	PS50057
Domain	Band_41_domain	PTK2B PTPN13 PTPN14 PLEKHH2 FRMPD2	2.63e-04	50	214	5	IPR019749
Domain	B41	PTK2B PTPN13 PTPN14 PLEKHH2 FRMPD2	2.63e-04	50	214	5	SM00295
Domain	Ubiquitin-rel_dom	SF3A1 YOD1 PTK2B PTPN13 PTPN14 PIK3CG UBXN10 FRMPD2 RAPGEF2	2.79e-04	184	214	9	IPR029071
Domain	MAPK_ERK3/4	MAPK4 MAPK6	3.89e-04	3	214	2	IPR008350
Domain	Dynein_HC_stalk	DNAH5 DNAH8 DNHD1	4.92e-04	14	214	3	IPR024743
Domain	Dynein_heavy_dom-2	DNAH5 DNAH8 DNHD1	4.92e-04	14	214	3	IPR013602
Domain	DHC_N2	DNAH5 DNAH8 DNHD1	4.92e-04	14	214	3	PF08393
Domain	MT	DNAH5 DNAH8 DNHD1	4.92e-04	14	214	3	PF12777
Domain	uDENN	DENND2A DENND4A DENND2B	4.92e-04	14	214	3	SM00800
Domain	DHC_fam	DNAH5 DNAH8 DNHD1	6.10e-04	15	214	3	IPR026983
Domain	uDENN	DENND2A DENND4A DENND2B	6.10e-04	15	214	3	PF03456
Domain	FH2	DIAPH1 FMNL1 FMNL3	6.10e-04	15	214	3	PS51444
Domain	Dynein_heavy	DNAH5 DNAH8 DNHD1	6.10e-04	15	214	3	PF03028
Domain	FH2_Formin	DIAPH1 FMNL1 FMNL3	6.10e-04	15	214	3	IPR015425
Domain	FH2	DIAPH1 FMNL1 FMNL3	6.10e-04	15	214	3	PF02181
Domain	Dynein_heavy_dom	DNAH5 DNAH8 DNHD1	6.10e-04	15	214	3	IPR004273
Domain	FH2	DIAPH1 FMNL1 FMNL3	6.10e-04	15	214	3	SM00498
Domain	DENN	DENND2A DENND4A DENND2B	7.44e-04	16	214	3	SM00799
Domain	DENN	DENND2A DENND4A DENND2B	7.44e-04	16	214	3	PF02141
Domain	dDENN	DENND2A DENND4A DENND2B	7.44e-04	16	214	3	PF03455
Domain	UDENN	DENND2A DENND4A DENND2B	7.44e-04	16	214	3	PS50946
Domain	DDENN	DENND2A DENND4A DENND2B	7.44e-04	16	214	3	PS50947
Domain	dDENN	DENND2A DENND4A DENND2B	7.44e-04	16	214	3	SM00801
Domain	dDENN_dom	DENND2A DENND4A DENND2B	7.44e-04	16	214	3	IPR005112
Domain	uDENN_dom	DENND2A DENND4A DENND2B	7.44e-04	16	214	3	IPR005113
Domain	DENN	DENND2A DENND4A DENND2B	7.44e-04	16	214	3	PS50211
Domain	DENN_dom	DENND2A DENND4A DENND2B	7.44e-04	16	214	3	IPR001194
Domain	-	ARMC6 ARFGEF2 XPO4 PUM2 ZYG11B FRYL WDFY4 ARVCF MROH2B	1.08e-03	222	214	9	1.25.10.10
Domain	KIND_dom	PTPN13 FRMPD2	1.28e-03	5	214	2	IPR011019
Domain	KIND	PTPN13 FRMPD2	1.28e-03	5	214	2	SM00750
Domain	KIND	PTPN13 FRMPD2	1.28e-03	5	214	2	PS51377
Domain	PH_dom-like	PTK2B PTPN13 PTPN14 PLCL2 PLCG1 PLEKHH2 PSD2 FRMPD2 ARHGEF18 NBEA WDFY4 ELMO3 ARHGEF2	1.31e-03	426	214	13	IPR011993
Domain	PH_12	PLCL2 ELMO3	1.90e-03	6	214	2	PF16457
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	RPN1 INTS1 ZZEF1 QRICH2 GFPT1 YOD1 P3H1 ALDH18A1 FLNB PCDHB12 NTMT1 RNF213 MAGEE2 PCDHA5 NBEA ICE1 GRIK5 HUWE1 PLXNA4 TMPO PHF14 EIF3A SLC26A11	6.62e-10	736	226	23	29676528
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	DENND4A WDR4 RPN1 PSMD3 PDIA2 CTAGE4 BSN PLIN1 DNAH8 SLC12A6 RPGRIP1 FLNA FLNB SMCHD1 MED8 CCT4 CTAGE6 LMOD3 CTAGE8 CEP83 PLXNA4 TMPO CTAGE15 PHF14 MYOM2 EIF3A ARHGEF2 MAPK6 ATP2A1 PRPH	2.09e-08	1442	226	30	35575683
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RABEP2 SLK KCNA4 DIAPH1 SPATS2 BSN WASF1 CACNB4 ARHGEF18 CCT4 NBEA GRIK3 CHD7 GRIK5 HUWE1 GRM3 BCL11B SEC24C ARVCF DOCK7 DCHS1 ARHGEF2 RAPGEF2 PHACTR1	2.23e-08	963	226	24	28671696
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SLK ERCC6L RPN1 PTPN13 PTPN14 TAF1 CSTF2T FLNA SMCHD1 MED8 HUWE1 CHAMP1 JMJD1C STEEP1 DOCK7 TMPO PATJ RSBN1L	2.51e-08	549	226	18	38280479
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	INTS1 PTPN13 DIAPH1 TIMM44 ARMC6 ARFGEF2 RNF213 CHTF18 LTN1	2.83e-08	104	226	9	31240132
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	SLK RPN1 SF3A1 PSMD3 GFPT1 ALDH18A1 PLCG1 BSN TIMM44 ARMC6 FLNA PSD2 SYNM CPSF6 POLR1C BUD23 CHTF18 PANK4 DOCK7	6.65e-08	653	226	19	33742100
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	FLNA FLNB SMCHD1 ARFGEF2 FRYL ICE1 THBS1 LTN1 DOCK7 TMPO ARHGEF2	1.00e-07	202	226	11	33005030
Pubmed	Association analysis of the glutamic acid decarboxylase 2 and the glutamine synthetase genes (GAD2, GLUL) with schizophrenia.	GAD2 GRIK3 GRIK5 GRM3	1.19e-07	8	226	4	19125103
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	RALGAPA1 RPN1 SF3A1 PSMD3 ALDH18A1 SPTY2D1 FLNA FLNB CPSF6 DHX37 SMCHD1 POLR1C CCT4 HUWE1 CHAMP1 CWC22 JMJD1C BUD23 SEC24C TMPO PHF14 EIF3A RSBN1L	1.53e-07	989	226	23	36424410
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ERCC4 PTPN13 PLCL2 DIAPH1 ANKRD12 PLCG1 HERC1 SPTY2D1 QSOX2 BRWD1 FLNA FLNB CPSF6 ARHGEF18 FRYL CHD7 HUWE1 WDFY4 SEC24C LTN1 TRAPPC10 ASXL2 PATJ PHACTR1	1.99e-07	1084	226	24	11544199
Pubmed	Regulation of oxidative DNA damage repair: the adenine:8-oxo-guanine problem.	POLL HUWE1 CDK2	2.71e-07	3	226	3	22370481
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	DDX19A ERCC6L SF3A1 VPS33A INTS1 PSMD3 DIAPH1 CPSF6 SMCHD1 ARFGEF2 MAGEE2 CCT4 CHD7 HUWE1 SEC24C TMPO ARHGEF2	3.17e-07	582	226	17	20467437
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RALGAPA1 DENND2A ZZEF1 GRAMD4 BSN CARNS1 SZT2 JADE2 SMCHD1 XPO4 AMBRA1 ICE1 CHAMP1 CWC22 FMNL3 HPS5	4.50e-07	529	226	16	14621295
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	ATP6V1A DDX19A RPN1 SF3A1 INTS1 PSMD3 DIAPH1 ALDH18A1 TIMM44 ARMC6 FLNA CPSF6 DHX37 SMCHD1 POLR1C PUM2 CCT4 CHD7 HUWE1 CWC22 SEC24C TMPO EIF3A ARHGEF2 RSBN1L CDK2	5.44e-07	1318	226	26	30463901
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	ATP6V1A DDX19A SLK DENND4A RPN1 SF3A1 PSMD3 GFPT1 DIAPH1 ALDH18A1 PLCG1 BSN TIMM44 DNAH5 DNHD1 FLNA FLNB CPSF6 DHX37 SMCHD1 CCT4 HUWE1 CWC22 DOCK7 TMPO EIF3A CDK2	7.05e-07	1425	226	27	30948266
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RALGAPA1 DENND2A ATP6V1A SLK RPN1 BCAS3 PSMD3 PTK2B BSN WASF1 SLC12A6 FLNA FLNB CACNB4 ARFGEF2 CCT4 NBEA GRM3 SEC24C ARVCF DOCK7 PLXNA4 TRAPPC10 TMPO EIF3A ARHGEF2 RAPGEF2	7.64e-07	1431	226	27	37142655
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	SF3A1 PSMD3 ALDH18A1 FLNA FLNB CPSF6 AMBRA1 CCT4 FRYL HUWE1 SEC24C TMPO EIF3A ARHGEF2 MAPK6 PRPH	7.69e-07	551	226	16	34728620
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DDX19A ERCC6 RPN1 PSMD3 GFPT1 PTPN14 DIAPH1 ALDH18A1 PLCG1 TIMM44 FLNA FLNB DHX37 SMCHD1 POLR1C AMBRA1 CCT4 CHD7 HUWE1 BUD23 SEC24C ARVCF CHTF18 LTN1 EIF3A ARHGEF2	8.88e-07	1353	226	26	29467282
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	DOCK4 DENND4A ERCC6L RPN1 SF3A1 PSMD3 NDN HNF4A QRICH2 GID8 HERC1 ARMC6 PCED1A CPSF6 DHX37 POLR1C XPO4 FRYL JMJD1C STEEP1 KCNIP4 ASXL2 EIF3A ARHGEF2 CDK2	1.16e-06	1284	226	25	17353931
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	RPN1 PSMD3 BSN DNAH5 NLRP5 DNHD1 SZT2 MED8 RNF213 DOCK7	1.20e-06	208	226	10	33230847
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SLK DENND4A ERCC4 ERCC6L ZZEF1 QSOX2 DHX37 AMBRA1 CWC22 JMJD1C ARVCF CHTF18 DOCK7 ARHGEF2 PATJ HPS5 RSBN1L	1.44e-06	650	226	17	38777146
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RABEP2 RALGAPA1 LZTR1 PSMD3 PTPN13 PTPN14 P3H1 PLCL2 ALDH18A1 HERC1 WASF1 XPO4 RNF213 CCT4 NBEA ZYG11B HUWE1 PPP2R5B ARVCF LTN1 TMPO ARHGEF2	1.60e-06	1049	226	22	27880917
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	DOCK4 ATP6V1A GAD2 RPN1 BCAS3 VPS33A PSMD3 KCNA4 SYT11 GID8 BSN TIMM44 WASF1 ARMC6 FLNA FLNB CACNB4 CPSF6 CCT4 NBEA HUWE1 DOCK7 PHACTR1	1.74e-06	1139	226	23	36417873
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	SF3A1 PTPN14 P3H1 DIAPH1 CPSF6 SEC24C DOCK7 EIF3A RAPGEF2 ATP2A1	1.99e-06	220	226	10	24550385
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	RALGAPA1 ATP6V1A ERCC6L ZZEF1 GID8 TIMM44 WASF1 CPSF6 XPO4 BUD23 STEEP1 PANK4 LTN1 FAHD1 CDK2	2.52e-06	533	226	15	25544563
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	ERCC6 RPN1 SF3A1 PSMD3 GFPT1 PTPN14 ALDH18A1 SPATS2 FLNA FLNB SYNM CPSF6 DHX37 SMCHD1 POLR1C CCT4 CWC22 THBS1 DOCK7 TMPO EIF3A ARHGEF2 PATJ RSBN1L	2.68e-06	1257	226	24	36526897
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	SLK ATXN7L2 RPN1 SF3A1 PSMD3 YOD1 PIK3CG P3H1 ALDH18A1 FLNA FLNB COL11A2 POLR1C AMBRA1 ZYG11B ICE1 HUWE1 DOCK7 ASXL2 EIF3A ARHGEF2	2.96e-06	1005	226	21	19615732
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TRPM4 LZTR1 BCAS3 INTS1 ZZEF1 GDPD5 ZNF276 POLL PLCG1 HERC1 FLNA B4GALNT4 SZT2 ARFGEF2 AMBRA1 FRYL ICE1 HUWE1 ARVCF LRP3 ARHGEF2 PPP1R16A	3.70e-06	1105	226	22	35748872
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ATP6V1A PTPN13 ALDH18A1 WASF1 SPTY2D1 SYNM CPSF6 ARFGEF2 RNF213 CCT4 NBEA HUWE1 AK8 LIPE SEC24C DOCK7 TMPO RAPGEF2	3.85e-06	777	226	18	35844135
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	NOL4 PTPN13 TAF1 CSTF2T FLNA FLNB ZSCAN4 ICE1 CHD7 HUWE1 CHAMP1 JMJD1C DOCK7	4.09e-06	418	226	13	34709266
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	NOL4 LZTR1 ERCC6 ATXN7L2 ZZEF1 AURKC PTPN14 DIAPH1 TAF1 QSOX2 ARMC6 BRWD1 RNF213 AMBRA1 C11orf16 CHAMP1 BCL11B PANK4 LTN1 RAPGEF2 RSBN1L CDH16	4.33e-06	1116	226	22	31753913
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	DNAH5 RNF213 NBEA HUWE1 CWC22 WDFY4 PLXNA4	4.57e-06	101	226	7	10997877
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KLHL14 PLEKHH2 CSTF2T SYNM ARHGEF18 RNF213 ATG14 MON1B WDFY4 JMJD1C DNAH17 LTN1 PHF14 EIF3A	4.94e-06	493	226	14	15368895
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RALGAPA1 ATP6V1A TRPM4 WDR4 HEBP2 BCAS3 DENND2B PTPN13 ANKRD12 PLCG1 SPATS2 SLC12A6 FLNB JADE2 FRMPD2 ARHGEF18 RNF213 FRYL HUWE1 JMJD1C PANK4 PHF14 RAPGEF2 MAPK6 PATJ HPS5	5.05e-06	1489	226	26	28611215
Pubmed	NAT2 and NER genetic variants and sporadic prostate cancer susceptibility in African Americans.	NAT2 ERCC4 ERCC6	5.34e-06	6	226	3	18026184
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	DDX19A LZTR1 PSMD3 GFPT1 PTPN14 GID8 PLCG1 PIPSL QSOX2 FLNA FLNB SMCHD1 XPO4 AMBRA1 CCT4 HUWE1 LTN1 EIF3A ATP2A1 CDK2	6.66e-06	974	226	20	28675297
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	RPN1 TAF1 FLNA FLNB CPSF6 SMCHD1 CCT4 JMJD1C TMPO	7.98e-06	203	226	9	22083510
Pubmed	A germline-specific class of small RNAs binds mammalian Piwi proteins.	SELENOS SF3A1 STK35 PTK2B GID8 ANKRD12 BSN QSOX2 DAGLB SYNM ATG14 SEC24C TMEM209	9.01e-06	450	226	13	16751776
Pubmed	Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.	DNAH5 DNAH8 DNAH17	9.30e-06	7	226	3	31178125
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	RABEP2 ATP6V1A DDX19A SLK WDR4 SF3A1 PSMD3 DPP8 ZZEF1 GFPT1 P3H1 DIAPH1 GID8 PLCG1 HERC1 FLNA FLNB POLR1C ARFGEF2 CCT4 FRYL HUWE1 SEC24C PANK4 EIF3A	1.02e-05	1455	226	25	22863883
Pubmed	Global landscape of HIV-human protein complexes.	RPN1 PTK2B DIAPH1 SPATS2 DAGLB ARFGEF2 XPO4 PUM2 RNF213 AMBRA1 HUWE1 EIF3A MAPK6	1.06e-05	457	226	13	22190034
Pubmed	Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.	RPN1 PSMD3 PTPN14 ALDH18A1 CCT4 HUWE1 CHTF18 TMPO ARHGEF2	1.09e-05	211	226	9	17314511
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	SF3A1 TAF1 FLNA FLNB SMCHD1 RNF213 CCT4 HUWE1 CHAMP1 TMPO CDK2	1.27e-05	332	226	11	32786267
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ATP6V1A SLK ERCC6L SF3A1 GFPT1 PTPN13 PLCG1 FLNA CPSF6 SMCHD1 PUM2 CCT4 ICE1 CHAMP1 STEEP1 TMPO EIF3A RSBN1L CDK2	1.30e-05	934	226	19	33916271
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	ATP6V1A PSMD3 PTPN14 SPATS2 BRWD1 POLR1C CCT4 HUWE1 CWC22 DOCK7 MOB3C TMPO	1.34e-05	399	226	12	37536630
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	DDX19A PSMD3 GFPT1 PLCG1 TIMM44 DNAH5 DNAH8 DHX37 POLR1C CCT4 GRIK5 HUWE1 CHAMP1 BUD23 SEC24C LTN1	1.70e-05	704	226	16	29955894
Pubmed	RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.	RPN1 PSMD3 DIAPH1 ALDH18A1 FLNA NTMT1 RNF213 CCT4 HUWE1 TMPO ATP2A1	1.76e-05	344	226	11	36282215
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	SF3A1 TAF1 CPSF6 SMCHD1 CHD7 CHAMP1 JMJD1C STEEP1 TMPO RSBN1L	1.82e-05	283	226	10	30585729
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	RALGAPA1 ERCC6L RPN1 SF3A1 PSMD3 GFPT1 PTPN13 ALDH18A1 TIMM44 FLNB CCT4 JMJD1C SEC24C DOCK7 TMPO PATJ	1.82e-05	708	226	16	39231216
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	ATP6V1A SLK RPN1 SF3A1 PSMD3 GFPT1 DIAPH1 ALDH18A1 GID8 SPATS2 TIMM44 FLNA FLNB CPSF6 SMCHD1 POLR1C CCT4 HUWE1 CHAMP1 SEC24C CHTF18 EIF3A ARHGEF2 CDK2	1.92e-05	1415	226	24	28515276
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	SF3A1 PSMD3 PTPN14 TIMM44 FLNA FLNB CPSF6 DHX37 SMCHD1 POLR1C AMBRA1 CCT4 HUWE1 BUD23 TMPO EIF3A MAPK4 ARHGEF2 CDK2	2.22e-05	971	226	19	33306668
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	ATP6V1A RPN1 SF3A1 PSMD3 GFPT1 PTPN14 DIAPH1 ALDH18A1 SPATS2 FLNA CPSF6 MED8 POLR1C CCT4 HUWE1 SEC24C ARVCF CHTF18 TRAPPC10 TMPO ARHGEF2 PATJ	2.41e-05	1247	226	22	27684187
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	VPS33A INTS1 PSMD3 GFPT1 PLCG1 FLNA FLNB SMCHD1 NBEA CHAMP1 SEC24C TMPO PRPH	2.61e-05	498	226	13	36634849
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	RALGAPA1 SELENOS ERCC6L DIAPH1 TIMM44 PUM2 ARHGEF18 RNF213 ICE1 CHD7 HUWE1 JMJD1C TMEM209 ARHGEF2 PATJ RSBN1L	2.77e-05	733	226	16	34672954
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	RPN1 SF3A1 INTS1 TAF1 FLNA DHX37 SMCHD1 CHD7 HUWE1 CHAMP1 BCL11B SEC24C TMPO EIF3A	3.18e-05	583	226	14	29844126
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	ATP6V1A DDX19A RPN1 PSMD3 GFPT1 FLNB CPSF6 SMCHD1 CCT4 HUWE1 JMJD1C TMPO EIF3A ATP2A1 CDK2	3.41e-05	665	226	15	30457570
Pubmed	Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.	DIAPH1 FMNL1 BRWD1 FMNL3	3.63e-05	29	226	4	21834987
Pubmed	Functional proteomics mapping of a human signaling pathway.	ERCC6 ZZEF1 DENND2B PLCL2 DIAPH1 HERC1 FMNL1 FLNA FLNB ZSCAN4 ARFGEF2 HUWE1 FMNL3 ASXL2	3.69e-05	591	226	14	15231748
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	DDX19A ERCC6L RPN1 ACR SF3A1 AURKC DNHD1 RPGRIP1 FLNA FLNB CPSF6 SMCHD1 CHAMP1 TMPO FAHD1	3.71e-05	670	226	15	22990118
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	RALGAPA1 DENND4A PTPN13 PTPN14 ALDH18A1 FMNL1 FRYL DOCK7 TRAPPC10 ARHGEF2 RAPGEF2 PATJ	3.99e-05	446	226	12	24255178
Pubmed	Mutational analysis of the hormone-sensitive lipase translocation reaction in adipocytes.	PLIN1 LIPE	4.20e-05	2	226	2	12832420
Pubmed	Disruption of the Flnb gene in mice phenocopies the human disease spondylocarpotarsal synostosis syndrome.	FLNA FLNB	4.20e-05	2	226	2	17635842
Pubmed	Overlapping expression of ARFGEF2 and Filamin A in the neuroependymal lining of the lateral ventricles: insights into the cause of periventricular heterotopia.	FLNA ARFGEF2	4.20e-05	2	226	2	16320251
Pubmed	The catalytic activity of the mitogen-activated protein kinase extracellular signal-regulated kinase 3 is required to sustain CD4+ CD8+ thymocyte survival.	MAPK4 MAPK6	4.20e-05	2	226	2	25002529
Pubmed	The adrenergic-induced ERK3 pathway drives lipolysis and suppresses energy dissipation.	MAPK4 MAPK6	4.20e-05	2	226	2	32139423
Pubmed	A PLCγ1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries.	TRPM4 PLCG1	4.20e-05	2	226	2	24866019
Pubmed	Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions.	FLNA FLNB	4.20e-05	2	226	2	21325628
Pubmed	F-circEA1 regulates cell proliferation and apoptosis through ALK downstream signaling pathway in non-small cell lung cancer.	ERCC4 ALK	4.20e-05	2	226	2	34633654
Pubmed	Functional interaction of hormone-sensitive lipase and perilipin in lipolysis.	PLIN1 LIPE	4.20e-05	2	226	2	19515989
Pubmed	SMCHD1 terminates the first embryonic genome activation event in mouse two-cell embryos and contributes to a transcriptionally repressive state.	ZSCAN4 SMCHD1	4.20e-05	2	226	2	31365290
Pubmed	Autoinhibition regulates cellular localization and actin assembly activity of the diaphanous-related formins FRLalpha and mDia1.	DIAPH1 FMNL1	4.20e-05	2	226	2	16943183
Pubmed	Crystal structures of the glutamate receptor ion channel GluK3 and GluK5 amino-terminal domains.	GRIK3 GRIK5	4.20e-05	2	226	2	20951142
Pubmed	ERK3 is required for metaphase-anaphase transition in mouse oocyte meiosis.	MAPK4 MAPK6	4.20e-05	2	226	2	20927325
Pubmed	Structural and functional aspects of filamins.	FLNA FLNB	4.20e-05	2	226	2	11336782
Pubmed	The variants at FLNA and FLNB contribute to the susceptibility of hypertension and stroke with differentially expressed mRNA.	FLNA FLNB	4.20e-05	2	226	2	33649519
Pubmed	cDNA cloning of a novel protein tyrosine phosphatase with homology to cytoskeletal protein 4.1 and its expression in T-lineage cells.	PTPN13 PTPN14	4.20e-05	2	226	2	8074693
Pubmed	The chaperonin CCT interacts with and mediates the correct folding and activity of three subunits of translation initiation factor eIF3: b, i and h.	CCT4 EIF3A	4.20e-05	2	226	2	24320561
Pubmed	Analysis of genetic inheritance in a family quartet by whole-genome sequencing.	DHODH DNAH5	4.20e-05	2	226	2	20220176
Pubmed	Basic fibroblast growth factor increases intracellular magnesium concentration through the specific signaling pathways.	PIK3CG PLCG1	4.20e-05	2	226	2	19711039
Pubmed	The non-classical MAP kinase ERK3 controls T cell activation.	MAPK4 MAPK6	4.20e-05	2	226	2	24475167
Pubmed	Cloning and characterization of p97MAPK, a novel human homolog of rat ERK-3.	MAPK4 MAPK6	4.20e-05	2	226	2	7969157
Pubmed	Depot-specific differences in perilipin and hormone-sensitive lipase expression in lean and obese.	PLIN1 LIPE	4.20e-05	2	226	2	20017959
Pubmed	Perilipin targets a novel pool of lipid droplets for lipolytic attack by hormone-sensitive lipase.	PLIN1 LIPE	4.20e-05	2	226	2	16243839
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	SLK KCNA4 DIAPH1 WASF1 NBEA GRIK5 GRM3 ARVCF RAPGEF2	4.27e-05	251	226	9	27507650
Pubmed	ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.	DDX19A GFPT1 ALDH18A1 FLNB CPSF6 NTMT1 PUM2 CWC22 SEC24C EIF3A	4.51e-05	315	226	10	26777405
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ERCC6L SF3A1 CSTF2T FLNA ARFGEF2 PUM2 CHD7 HUWE1 CHAMP1 SEC24C CHTF18 TRAPPC10 TMPO PHF14 ARHGEF2 CDK2	5.27e-05	774	226	16	15302935
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	DDX19A BCAS3 GFPT1 FLNA FLNB SMCHD1 POLR1C AMBRA1 HUWE1 DOCK7 TMEM209 TMPO EIF3A	5.32e-05	534	226	13	35032548
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RALGAPA1 DOCK4 DENND4A ERCC6L BCAS3 TSSK2 DPP8 DENND2B PTK2B PTPN13 PTPN14 FRYL DOCK7 MAPK4 ARHGEF2 RAPGEF2 PATJ	5.42e-05	861	226	17	36931259
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	XPO4 AMBRA1 ZYG11B DOCK7 ASXL2 PHACTR1	5.64e-05	102	226	6	11214970
Pubmed	A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors.	GAD2 DIAPH1 BCL11B	5.70e-05	12	226	3	22246438
Pubmed	Global proteomics of Ubqln2-based murine models of ALS.	RABEP2 YOD1 PIPSL CSTF2T FLNA FLNB SMCHD1 FRYL SEC24C	5.77e-05	261	226	9	33277362
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	RPN1 SF3A1 SIMC1 TAF1 ALK FLNA CPSF6 SMCHD1 ICE1 CHD7 CHAMP1 CWC22 JMJD1C STEEP1 TMPO PHF14 ATP2A1 RSBN1L	5.84e-05	954	226	18	36373674
Pubmed	MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity.	RPN1 FMNL1 QSOX2 FRYL FMNL3 LTN1 ARHGEF2	5.97e-05	150	226	7	22678362
Pubmed	Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line.	NDN DIAPH1 ATG14 CDK2	6.13e-05	33	226	4	24569637
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	ATP6V1A RPN1 PSMD3 ALDH18A1 GID8 TIMM44 FLNA FLNB JADE2 POLR1C XPO4 RNF213 CCT4 HUWE1 PANK4 LTN1 DOCK7 TMEM209 TRAPPC10 TMPO EIF3A ARHGEF2 CDK2	7.18e-05	1440	226	23	30833792
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	RABEP2 TRPM4 VPS33A ZZEF1 PIPSL DHX37 STEEP1 LTN1	7.99e-05	212	226	8	33853758
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	ATP6V1A DDX19A RPN1 VPS33A INTS1 PSMD3 GFPT1 ALDH18A1 PIPSL TIMM44 ARMC6 DHX37 POLR1C AMBRA1 CCT4 HUWE1 CHTF18 PANK4 TMEM209 TMPO CDK2	8.04e-05	1257	226	21	37317656
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ERCC6L VPS33A GFPT1 USH1G NXF5 BSN WASF1 MED8 ATG14 NBEA CHD7 THBS1 ARVCF ARHGEF2	8.34e-05	638	226	14	31182584
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	ATP6V1A RPN1 VPS33A PSMD3 ZZEF1 GFPT1 DIAPH1 ALDH18A1 FLNA FLNB CPSF6 CP CCT4 HUWE1 EIF3A ATP2A1	8.58e-05	807	226	16	30575818
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	RPN1 PSMD3 HERC1 DNAH5 FLNA FLNB CCT4 PATJ RSBN1L	9.09e-05	277	226	9	30745168
Interaction	CTAGE1 interactions	CTAGE4 CTAGE6 CTAGE8 CTAGE15	2.96e-06	10	224	4	int:CTAGE1
Cytoband	19q13.43	ZSCAN5DP AURKC NLRP5 ZSCAN4 ZNF835	7.36e-05	87	226	5	19q13.43
Cytoband	11p14	KCNA4 HPS5	1.44e-04	4	226	2	11p14
Cytoband	7q35	CTAGE4 CTAGE6 CTAGE8 CTAGE15	1.60e-04	55	226	4	7q35
Cytoband	Ensembl 112 genes in cytogenetic band chr7q35	CTAGE4 CTAGE6 CTAGE8 CTAGE15	3.24e-04	66	226	4	chr7q35
GeneFamily	CTAGE family	CTAGE4 CTAGE6 CTAGE8 CTAGE15	5.63e-06	15	149	4	907
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	PTK2B PTPN13 PTPN14 PLEKHH2 FRMPD2	5.59e-05	50	149	5	1293
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	WASF1 SYNM ARFGEF2 NBEA	8.96e-05	29	149	4	396
GeneFamily	Dyneins, axonemal	DNAH5 DNAH8 DNAH17	3.43e-04	17	149	3	536
GeneFamily	Glutamate ionotropic receptor kainate type subunits	GRIK3 GRIK5	6.64e-04	5	149	2	1199
GeneFamily	Guanylate cyclase receptors\|DENN/MADD domain containing	DENND2A DENND4A DENND2B	1.10e-03	25	149	3	504
GeneFamily	WD repeat domain containing\|ERCC excision repair associated	ERCC4 ERCC6	1.38e-03	7	149	2	1268
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEA WDFY4	2.34e-03	9	149	2	1230
Coexpression	GSE27241_WT_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP	TSSK2 GFPT1 PTPN14 PIK3CG ALDH18A1 SPATS2 RNF213 CHD7 JMJD1C FMNL3 PHF14	3.21e-07	172	226	11	M8234
Coexpression	GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_UP	TRPM4 ERCC4 PLCL2 TOR1B HERC1 CARNS1 ADCK5 ASXL2 SLC26A11 TMEM140	1.00e-05	200	226	10	M4313
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZC3H12D ANKRD12 PLCG1 HERC1 CTAGE4 ALK BRWD1 SMCHD1 RNF213 FRYL ZAP70 BCL11B	3.41e-10	193	226	12	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RALGAPA1 DENND4A ZC3H12D RSRP1 ANKRD12 HERC1 SMCHD1 RNF213 JMJD1C ZAP70 BCL11B	4.44e-09	192	226	11	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	RALGAPA1 ZC3H12D RSRP1 ANKRD12 HERC1 SMCHD1 RNF213 HUWE1 JMJD1C BCL11B	3.20e-08	181	226	10	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RALGAPA1 DENND4A RSRP1 ANKRD12 HERC1 SMCHD1 RNF213 HUWE1 JMJD1C RAPGEF2	4.58e-08	188	226	10	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	RALGAPA1 DENND4A ZC3H12D RSRP1 ANKRD12 HERC1 SMCHD1 RNF213 JMJD1C	1.09e-07	156	226	9	1545169694f686d28648a68b552c2ae606599d66
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RALGAPA1 DENND4A ZC3H12D ANKRD12 HERC1 SMCHD1 RNF213 JMJD1C BCL11B	2.39e-07	171	226	9	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	wk_15-18-Epithelial-PNS-KCNIP4+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NOL4 C4orf50 SYT11 BSN ALK GRIK3 KCNH4 KCNIP4 PRPH	3.51e-07	179	226	9	e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZC3H12D ANKRD12 HERC1 CTAGE4 SMCHD1 RNF213 FRYL ZAP70 BCL11B	7.85e-07	197	226	9	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	PCW_05-06-Neuronal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	KCNA4 SYT11 CLVS2 ALK GRIK3 RLBP1 PLXNA4 PRPH	5.28e-06	187	226	8	03a2ed85b171c887d4f3b0f4fe2e1cb4a853e658
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	ZC3H12D PLCG1 HERC1 SMCHD1 RNF213 NSUN6 BCL11B	5.90e-06	135	226	7	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN14 FLNA SYNM FRYL GRIK3 JMJD1C THBS1 DKK3	6.17e-06	191	226	8	8691eba35793e4e90f93d50c2145847ee51289f7
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZC3H12D RSRP1 ANKRD12 FMNL1 SMCHD1 RNF213 ZAP70 BCL11B	6.91e-06	194	226	8	af7428582b96a500f255c45efc02b6c10c4740d9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A PTPN14 PLEKHH2 DNAH5 RNF213 KCNIP4 PATJ PHACTR1	6.91e-06	194	226	8	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZC3H12D RSRP1 ANKRD12 FMNL1 SMCHD1 RNF213 ZAP70 BCL11B	6.91e-06	194	226	8	4138f3e8aa214504fca03962a43250670ae45215
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZC3H12D RSRP1 ANKRD12 FMNL1 SMCHD1 RNF213 ZAP70 BCL11B	6.91e-06	194	226	8	906fe1689906d1498acf6fd26a215c7e5a854a38
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NOL4 DDX19A CLVS2 TOR1B PLIN1 SYNM MED8 MROH2B	8.02e-06	198	226	8	24bc53bd8ef8f4f2f4fc377aeee75126ad5d311f
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	SYT11 DIAPH1 PLCG1 FLNA RNF213 HUWE1 ZAP70 MYOM2	8.63e-06	200	226	8	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	ZC3H12D RSRP1 ANKRD12 PLCG1 SMCHD1 BCL11B PATJ	1.23e-05	151	226	7	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PLCG1 BRWD1 CP FRYL BCL11B CHTF18 PATJ	1.86e-05	161	226	7	5fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBLN2 KCNA4 SYT11 USH1G GRIK3 CHD7 RLBP1	2.54e-05	169	226	7	2456b3e7776e8a2214972be1b4d66a3ca5480ae0
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DDX19A INTS1 SIMC1 QSOX2 PCED1A CP LRP3	2.64e-05	170	226	7	b1a16600754e0c12f7d39c9221f1b03135833f16
ToppCell	normal-na-Lymphocytic_T-T4_em-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	PTPN13 ZC3H12D ANKRD12 SMCHD1 GRIK5 SMCO2 EIF3A	2.74e-05	171	226	7	61318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell	MS-Treg-naive_CD4\|MS / Condition, Cell_class and T cell subcluster	PTPN14 P3H1 FLNB AMBRA1 MSANTD4 RAPGEF2 CDK2	3.80e-05	180	226	7	7ca083616926d98420fa11a6e5ebc981623f79ac
ToppCell	wk_20-22-Hematologic-Meg-ery-Definitive_erythroblast\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DENND4A YOD1 RSRP1 HERC1 QSOX2 ATG14 RAPGEF2	4.08e-05	182	226	7	0c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C4orf50 PTK2B ALK NBEA GRIK5 ARVCF PRPH	4.08e-05	182	226	7	be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTK2B PIK3CG WASF1 GRIK3 SNED1 PLXNA4 MYOM2	4.08e-05	182	226	7	35b2a5625323bf0917214d3b82fafc4a8f5e75ff
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 GDPD5 ALK ARX GRIK3 LMOD3 BCL11B	4.22e-05	183	226	7	d2074b13b4831ec18c81273d9a1ff673c3f6a16d
ToppCell	PCW_05-06-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	NOL4 CLVS2 ALK GRIK3 RLBP1 LBX2 PRPH	4.22e-05	183	226	7	9dfb398b9995d562864fe688861a831ada0814cd
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTK2B PIK3CG WASF1 GRIK3 SNED1 PLXNA4 MYOM2	4.37e-05	184	226	7	9a185e6ea86bbfbb48bfe88650a8c05ceba78d7f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERCC6 ATXN7L2 CFAP54 SPATS2 DNAH5 C11orf16 PLXNA4	4.53e-05	185	226	7	05bc89a566b0db90ae06506e067190a4739a0974
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLK DENND4A SPTY2D1 CP HUWE1 JMJD1C EIF3A	4.53e-05	185	226	7	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 FBLN2 SIMC1 PLCG1 PLEKHH2 PATJ HPS5	4.68e-05	186	226	7	77bebf576eb9b96ecb4fefb8a82a31aaaa917fc0
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KCNA4 CLVS2 ALK GRIK3 RLBP1 PLXNA4 PHACTR1	4.68e-05	186	226	7	3113c85d0ac5fc46532c19b1bb71f34b985e1276
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	ANKRD12 TAF1 SPTY2D1 SMCHD1 CHAMP1 LTN1 ASXL2	4.68e-05	186	226	7	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 FBLN2 SIMC1 PLCG1 PLEKHH2 PATJ HPS5	4.68e-05	186	226	7	13bc41c60fd628af31899a5e8b480e06cc4781be
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GAD2 PTPN13 NLRP5 CP ELMO3 SEPTIN12	4.68e-05	127	226	6	5b0adbcafad31a6759c9bdce2f7f9591a8edc450
ToppCell	droplet-Liver-nan-3m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 DPP8 PLCL2 ALDH18A1 SPATS2 PHACTR1	4.68e-05	127	226	6	39fa20a55de3af1a62ab5dfa4877879db3935ac2
ToppCell	Control-B_intermediate-6\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SYT11 DIAPH1 SPATS2 FLNA FLNB RNF213 WDFY4	5.18e-05	189	226	7	11cb9a16f1de8f60af2073ed7ea6d4f41c02f299
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A PTPN13 PTPN14 PLEKHH2 AMBRA1 KCNIP4 PATJ	5.18e-05	189	226	7	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A CFAP54 PTPN14 PLEKHH2 DNAH5 KCNIP4 PHACTR1	5.36e-05	190	226	7	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 GDPD5 ALK ARX GRIK3 LMOD3 BCL11B	5.36e-05	190	226	7	3f22c118d552345f731d4d49f0bcb5765d93de3b
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A NDN PLEKHH2 SNED1 THBS1 PLXNA4 DKK3	5.36e-05	190	226	7	d60395739458d7f47a3350ade751fe3819500320
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A CFAP54 PTPN14 PLEKHH2 DNAH5 KCNIP4 PHACTR1	5.54e-05	191	226	7	5a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A CFAP54 PTPN14 PLEKHH2 DNAH5 KCNIP4 PHACTR1	5.54e-05	191	226	7	55ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN14 FLNA SYNM GRIK3 JMJD1C THBS1 DKK3	5.54e-05	191	226	7	2f733d510a4862565a817f59829d8387d7ea26d9
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NOL4 HEBP2 SYT11 NBEA CHD7 ARVCF PRPH	5.72e-05	192	226	7	fe9297cb65234d9f511bab1a5dbf2679d5a4cd15
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	DENND4A KLHL14 HERC1 QSOX2 SMCHD1 WDFY4 JMJD1C	5.72e-05	192	226	7	aee6522d25e012231cdb905ce047295cb64d6e82
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A PTPN14 PLEKHH2 DNAH5 KCNIP4 PATJ PHACTR1	5.91e-05	193	226	7	42df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A PTPN14 PLEKHH2 DNAH5 KCNIP4 PATJ PHACTR1	5.91e-05	193	226	7	f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A PTPN14 PLEKHH2 DNAH5 RNF213 KCNIP4 PHACTR1	6.31e-05	195	226	7	938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM4 FLNA CP GRIK3 JMJD1C THBS1 DKK3	6.31e-05	195	226	7	717e6a66bad50e711442d71360b540789646b334
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A PTPN14 PLEKHH2 DNAH5 RNF213 KCNIP4 PHACTR1	6.31e-05	195	226	7	d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM4 FLNA CP GRIK3 JMJD1C THBS1 DKK3	6.31e-05	195	226	7	10774b5ce17d4edd23dbf4709b11cc87cc2b87be
ToppCell	Bronchus_Control_(B.)-Immune-TX-TRAM-1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	PNPLA1 SYT11 PLCL2 TIMM44 SLC12A6 WDFY4 FMNL3	6.31e-05	195	226	7	dabf667875ed48fdce4f803f5ead39c71a6df42b
ToppCell	COVID-19_Severe-Lymphoid_T/NK-gd_T\|COVID-19_Severe / Disease group, lineage and cell class	SYT11 DIAPH1 FLNA JADE2 RNF213 ZAP70 MYOM2	6.31e-05	195	226	7	9990440bda7fac5d00ef80444fab07459be625e1
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTK2B KCNA4 CLVS2 PLCL2 BSN FMNL1 KCNIP4	6.31e-05	195	226	7	ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN14 SYNM CP GRIK3 JMJD1C THBS1 DKK3	6.31e-05	195	226	7	f41a68b7c2621594db8d8952e301eeadc96be26f
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	DENND2B SYT11 PLEKHH2 GRIK5 LIPE MOB3C ARHGEF2	6.31e-05	195	226	7	5562665dd3beb70e2358aa32611a337bef5731c1
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	PTPN13 ANKRD12 PLCG1 SMCHD1 ZAP70 BCL11B PATJ	6.31e-05	195	226	7	22191d361af136942508f1553ff41a626ed982ad
ToppCell	healthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SYT11 DIAPH1 FLNA SYNM RNF213 ZAP70 BCL11B	6.52e-05	196	226	7	af00c31612e4fe068e5fccae05368edba46bbd20
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SYT11 DIAPH1 FLNA JADE2 RNF213 ZAP70 MYOM2	6.52e-05	196	226	7	418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYT11 DIAPH1 FLNA JADE2 RNF213 ZAP70 MYOM2	6.52e-05	196	226	7	581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SYT11 DIAPH1 FLNA JADE2 RNF213 ZAP70 MYOM2	6.52e-05	196	226	7	6beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYT11 DIAPH1 FLNA JADE2 RNF213 ZAP70 MYOM2	6.52e-05	196	226	7	c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCell	ILEUM-non-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	RSRP1 ANKRD12 JMJD1C HPS5 SLC26A11 PHACTR1	6.58e-05	135	226	6	b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCell	10x5'-Liver-Lymphocytic_T_CD4\|Liver / Manually curated celltypes from each tissue	PTPN13 ZC3H12D ANKRD12 PLCG1 SMCHD1 JMJD1C BCL11B	6.73e-05	197	226	7	4891111894b741555f549deec6af8006376d9358
ToppCell	Bronchus_Control_(B.)-Endothelial-TX\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	NOL4 B4GALNT4 COL11A2 GRIK3 BCL11B MAPK4 DKK3	6.94e-05	198	226	7	feac39036b5c0ab97b524cc366286942d136d42f
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBLN2 SYT11 GRIK3 CHD7 RLBP1 DKK3 PRPH	6.94e-05	198	226	7	6e314dc820db9c53fe7fc7c96bed4d7d9a325160
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DENND2A PLEKHH2 CP THBS1 PLXNA4 LRP3 DKK3	7.17e-05	199	226	7	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RALGAPA1 ANKRD12 HERC1 SMCHD1 RNF213 FRYL ZAP70	7.17e-05	199	226	7	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBLN2 SYT11 GRIK3 CHD7 RLBP1 DKK3 PRPH	7.17e-05	199	226	7	5f350d9c7da9ac111bf22623dd4fed7f7983c9fc
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GDPD5 PTPN14 SYNM EID2B ZNF835 SNED1 DKK3	7.40e-05	200	226	7	36de49593cf6ff1c9229fcceb150c1d68658a360
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T\|COVID-19_Severe / Disease, condition lineage and cell class	SYT11 DIAPH1 FLNA JADE2 RNF213 ZAP70 MYOM2	7.40e-05	200	226	7	f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCell	TCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Non-Seminoma-_Embryonal_Carcinoma\|TCGA-Testes / Sample_Type by Project: Shred V9	GAD2 ACR QRICH2 ZSCAN4 ARX SEPTIN12	7.74e-05	139	226	6	6b58d01ce9d9ac23434333f9faf1bb0eef14ba90
ToppCell	Tracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	PTPN13 FBLN2 SIMC1 POLL JADE2 TMEM79	8.05e-05	140	226	6	0e1e9281de87df178ac41ed6b697b4fa09be2749
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	QRICH2 KCNA4 ZAP70 BCL11B SLC26A11 ATP2A1	8.38e-05	141	226	6	31e0984f09983e83a814424f74c871c1c5a3a789
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	QRICH2 KCNA4 ZAP70 BCL11B SLC26A11 ATP2A1	8.38e-05	141	226	6	d7d3c3932651d90fa4f3c4e3df16f4b677faaf9f
ToppCell	ASK454-Epithelial-Secretory\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	POLL CARNS1 EID2B CP JMJD1C LIPE	9.41e-05	144	226	6	8e693b50bd6c69ce68f44ca6e51f6d0c7f80d82c
ToppCell	P03-Hematopoietic-Immune-immune_cell_unspecified\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PTK2B ZC3H12D KLHL14 FMNL1 WDFY4 MCOLN3	1.13e-04	149	226	6	43d756f81d532b5c7f2306e6af9d072d496cbc8e
ToppCell	P03-Hematopoietic-Immune\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PTK2B ZC3H12D KLHL14 FMNL1 WDFY4 MCOLN3	1.13e-04	149	226	6	1c5a2572741c47246d455c865e8e1677c9f49598
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	ATXN7L2 PDE8A SZT2 JMJD1C NSUN6 CEP83	1.13e-04	149	226	6	768877bade04ca0321593b8470b5011ad8270431
ToppCell	COVID-19_Moderate-multiplets\|World / disease group, cell group and cell class	GDPD5 PLCG1 RNF213 ZAP70 BCL11B MYOM2	1.46e-04	156	226	6	afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-2\|TCGA-Lung / Sample_Type by Project: Shred V9	NOL4 C4orf50 CLVS2 BSN TMPO CDK2	1.56e-04	158	226	6	9dea15b28f64206bac0e785df6f36a2cc9010ac7
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PPP1R3G PLCG1 DNHD1 ZAP70 BCL11B MOB3C	1.62e-04	159	226	6	b1d5ebd0c186b6d0279dab20d8f3b4a915acdc1f
ToppCell	Severe-B_naive-1\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RSRP1 JADE2 ARHGEF18 ICE1 WDFY4 PATJ	1.62e-04	159	226	6	2881b054bbeb479221ee3c38bbd9b0815b123579
ToppCell	facs-Lung-Endomucin-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC72 GDPD5 AMBRA1 GRM3 BCL11B LTN1	1.67e-04	160	226	6	0fee84844733d36805e1df90ca09478169746708
ToppCell	facs-Lung-Endomucin-3m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC72 GDPD5 AMBRA1 GRM3 BCL11B LTN1	1.67e-04	160	226	6	5c68d6a76c59e3a7e668ae5471396478a55756ac
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2B FLNA ZAP70 BUD23 CHTF18 DKK3	1.73e-04	161	226	6	a7e09cf2ca6cd70d40d08440fe9c5ab9befa1b79
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2B FLNA ZAP70 BUD23 CHTF18 DKK3	1.73e-04	161	226	6	08920a716f6ec62538e361211455a30ad726d7be
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	WDR4 QRICH2 FBLN2 TMEM79 CHTF18 PPP1R16A	1.85e-04	163	226	6	63b0badaee3b2d827b1f4524510e3384d8f8fcde
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1\|E16.5-samps / Age Group, Lineage, Cell class and subclass	DOCK4 GAD2 RSRP1 CACNB4 CP LIPE	1.85e-04	163	226	6	f1ec2625b52664308968b01d8e0275e1e0751480
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERCC6 GRAMD4 SIMC1 DNAH8 ARMC6 ARHGEF2	1.91e-04	164	226	6	950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERCC6 GRAMD4 SIMC1 DNAH8 ARMC6 ARHGEF2	1.91e-04	164	226	6	c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CARNS1 JADE2 NBEA ZAP70 BCL11B PHF14	1.91e-04	164	226	6	d8ecb3de6e34f5f574449e3d2f26fa0b2b7e84e8
ToppCell	droplet-Liver-nan-3m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERCC6 GRAMD4 SIMC1 DNAH8 ARMC6 ARHGEF2	1.91e-04	164	226	6	bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCell	NS-control-d_0-4-Myeloid-pDC\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FMNL1 WDFY4 FMNL3 PLXNA4 ATP2A1 PHACTR1	1.98e-04	165	226	6	8b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue-Colon_normal_tissue-9\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ARHGEF18 GRIK3 GRIK5 ZNF835 MAPK4 PRPH	2.04e-04	166	226	6	68e6fc7c0040bbe48a93f96ecf28afffdc626845
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KCNA4 CLVS2 ALK GRIK3 RLBP1 PLXNA4	2.11e-04	167	226	6	49b19159c62d33d65ed1e59a148c11ae902fd41c
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-regulatory_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYT11 ZC3H12D B4GALNT4 ZAP70 KCNH4 BCL11B	2.11e-04	167	226	6	89e3aab0d2359d2a44b50db328e7c542f73888ea
ToppCell	droplet-Heart-nan-24m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DHODH CCDC15 NLRP5 FRYL HPS5 PRPH	2.11e-04	167	226	6	a35ace2c722936d2a3e1f0826e5b6ec6b1340d2b
Disease	22q11 partial monosomy syndrome	JMJD1C SEC24C ARVCF	2.98e-05	9	212	3	C3266101
Disease	Asymmetric crying face association	JMJD1C SEC24C ARVCF	4.23e-05	10	212	3	C0431406
Disease	22q11 Deletion Syndrome	JMJD1C SEC24C ARVCF	4.23e-05	10	212	3	C2936346
Disease	Periventricular nodular heterotopia	FLNA ARFGEF2	5.14e-05	2	212	2	cv:C1868720
Disease	X-21358 measurement	CCDC15 CARNS1	5.14e-05	2	212	2	EFO_0022120
Disease	polyneuropathy due to drug (is_implicated_in)	ERCC4 ERCC6	5.14e-05	2	212	2	DOID:14184 (is_implicated_in)
Disease	monocyte count	RALGAPA1 DENND4A RPN1 BCAS3 PSMD3 BCL6 DPP8 DENND2B PTK2B ZNF276 PIK3CG PLCL2 DIAPH1 GID8 DAGLB PCED1A FLNB SZT2 JADE2 ZYG11B TMEM87A ARVCF MAPK4	8.45e-05	1320	212	23	EFO_0005091
Disease	granulocyte percentage of myeloid white cells	RPN1 PSMD3 BCL6 DPP8 DAGLB FLNB TCP11 CHD7 JMJD1C	1.49e-04	268	212	9	EFO_0007997
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNA FLNB	1.53e-04	3	212	2	DOID:0080096 (implicated_via_orthology)
Disease	Cockayne Syndrome, Type I	ERCC4 ERCC6	1.53e-04	3	212	2	C0751039
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNA FLNB	1.53e-04	3	212	2	DOID:0111190 (implicated_via_orthology)
Disease	neutrophil gelatinase-associated lipocalin measurement	PSMD3 CHD7	1.53e-04	3	212	2	EFO_0021964
Disease	Heterotopia, Periventricular, Autosomal Recessive	ARFGEF2 DCHS1	1.53e-04	3	212	2	C1842563
Disease	DiGeorge Syndrome	JMJD1C SEC24C ARVCF	1.91e-04	16	212	3	C0012236
Disease	CONOTRUNCAL ANOMALY FACE SYNDROME	JMJD1C SEC24C ARVCF	1.91e-04	16	212	3	C0795907
Disease	Shprintzen syndrome	JMJD1C SEC24C ARVCF	1.91e-04	16	212	3	C0220704
Disease	osteochondrodysplasia (is_implicated_in)	FLNA FLNB COL11A2	3.25e-04	19	212	3	DOID:2256 (is_implicated_in)
Disease	bilirubin measurement	ERCC4 BCAS3 BCL6 HNF4A KCNA4 RSRP1 ARMC6 JMJD1C DOCK7 ASXL2 PHACTR1	3.83e-04	442	212	11	EFO_0004570
Disease	basophil percentage of leukocytes	RPN1 PSMD3 BCL6 DPP8 PLCL2 CHD7 JMJD1C PHACTR1	3.95e-04	243	212	8	EFO_0007992
Disease	Global developmental delay	INTS1 DIAPH1 TAF1 SZT2 NBEA PHACTR1	4.12e-04	133	212	6	C0557874
Disease	activities of daily living score measurement	NOL4 GRIK5 PATJ	4.42e-04	21	212	3	EFO_0008451
Disease	Familial partial lipodystrophy	PLIN1 LIPE	5.07e-04	5	212	2	cv:C0271694
Disease	immunoglobulin superfamily DCC subclass member 4 measurement	DENND4A DPP8	5.07e-04	5	212	2	EFO_0801690
Disease	attention deficit hyperactivity disorder, autism spectrum disorder, intelligence	ERCC4 DPP8 PLCL2 BSN BRWD1 MED8 ARFGEF2 CWC22 JMJD1C PPP1R16A	6.52e-04	398	212	10	EFO_0003756, EFO_0003888, EFO_0004337
Disease	airway responsiveness measurement	BCAS3 TCP11 WDFY4	6.62e-04	24	212	3	EFO_0006897
Disease	hearing impairment	ERCC6 USH1G DIAPH1 COL11A2 CHD7	7.22e-04	98	212	5	C1384666
Disease	pappalysin-1 measurement	RPN1 CHD7	7.56e-04	6	212	2	EFO_0802845
Disease	periventricular nodular heterotopia (is_implicated_in)	FLNA ARFGEF2	7.56e-04	6	212	2	DOID:0050454 (is_implicated_in)
Disease	level of Phosphatidylcholine (18:2_18:2) in blood serum	DOCK7 PLXNA4	7.56e-04	6	212	2	OBA_2045106
Disease	Cockayne syndrome (implicated_via_orthology)	ERCC4 ERCC6	7.56e-04	6	212	2	DOID:2962 (implicated_via_orthology)
Disease	Familial Partial Lipodystrophy, Type 3	PLIN1 LIPE	1.05e-03	7	212	2	C1720861
Disease	Familial Partial Lipodystrophy, Type 2	PLIN1 LIPE	1.05e-03	7	212	2	C1720860
Disease	Familial Partial Lipodystrophy, Type 1	PLIN1 LIPE	1.05e-03	7	212	2	C1720859
Disease	Periventricular Nodular Heterotopia	FLNA ARFGEF2	1.05e-03	7	212	2	C1868720
Disease	fibrinogen measurement	HNF4A DHODH GRIK5 TMEM87A JMJD1C	1.16e-03	109	212	5	EFO_0004623
Disease	neutrophil count, basophil count	RPN1 PSMD3 HNF4A PCDHA5 CHD7 JMJD1C MAPK4	1.23e-03	224	212	7	EFO_0004833, EFO_0005090
Disease	syndromic X-linked intellectual disability (implicated_via_orthology)	ARX HUWE1	1.40e-03	8	212	2	DOID:0060309 (implicated_via_orthology)
Disease	pseudouridine measurement	PDE8A GRIK5	1.40e-03	8	212	2	EFO_0021126
Disease	Familial partial lipodystrophy	PLIN1 LIPE	1.40e-03	8	212	2	C0271694
Disease	Intellectual Disability	RALGAPA1 WDR4 NXF5 DIAPH1 TAF1 WASF1 NBEA CHAMP1 BCL11B PHACTR1	1.56e-03	447	212	10	C3714756
Disease	mitral valve prolapse (is_implicated_in)	FLNA DCHS1	1.79e-03	9	212	2	DOID:988 (is_implicated_in)
Disease	response to 4'-epidoxorubicin, response to antineoplastic agent	GSX1 ICE1	1.79e-03	9	212	2	GO_0097327, GO_1902522
Disease	PITUITARY DWARFISM I	ERCC4 WDR4	1.79e-03	9	212	2	C0342573
Disease	triglyceride measurement, physical activity	NAT2 JMJD1C DOCK7	1.86e-03	34	212	3	EFO_0003940, EFO_0004530
Disease	Schizophrenia	DOCK4 GAD2 SYT11 CLVS2 PLCL2 ALK AMBRA1 CP GRIK3 GRIK5 GRM3 THBS1 ARVCF EDEM2 DKK3	1.91e-03	883	212	15	C0036341
Disease	coronary artery disease	NAT2 SLK BCAS3 C4orf50 DENND2B GDPD5 ZC3H12D PLCG1 PLEKHH2 BSN ALK DAGLB ARFGEF2 RNF213 ARVCF EDEM2 RAPGEF2 PHACTR1	2.57e-03	1194	212	18	EFO_0001645
Disease	refractive error	BCAS3 ZZEF1 KCNA4 QSOX2 SLC12A6 FRMPD2 NBEA CHD7	2.58e-03	326	212	8	MONDO_0004892
Disease	Diabetic Retinopathy	GAD2 THBS1	2.71e-03	11	212	2	C0011884
Disease	5-acetylamino-6-amino-3-methyluracil measurement	NAT2 CARNS1	2.71e-03	11	212	2	EFO_0800951
Disease	sexual dimorphism measurement	RALGAPA1 VPS33A BCL6 ZZEF1 HNF4A PNPLA1 HERC1 BSN CARNS1 QSOX2 CHCHD7 TCP11 FRYL JMJD1C EDEM2 ASXL2 PATJ	2.76e-03	1106	212	17	EFO_0021796
Disease	Autistic Disorder	DOCK4 LZTR1 PIK3CG CP NBEA WDFY4 JMJD1C	2.91e-03	261	212	7	C0004352
Disease	basophil percentage of granulocytes	RPN1 BCL6 CHD7 JMJD1C	3.06e-03	83	212	4	EFO_0007995
Disease	Congenital small ears	DHODH POLR1C CHD7	3.19e-03	41	212	3	C0152423
Disease	retinitis pigmentosa (is_implicated_in)	RPGRIP1 ARHGEF18 RLBP1	3.19e-03	41	212	3	DOID:10584 (is_implicated_in)
Disease	cleft palate (is_implicated_in)	FLNB COL11A2	3.23e-03	12	212	2	DOID:674 (is_implicated_in)
Disease	serum metabolite measurement	RALGAPA1 NAT2 ERCC4 PDE8A RPN1 NDN ALK GRIK5 BCL11B DNAH17 DOCK7 KCNIP4 MYOM2 HPS5 PHACTR1	3.61e-03	945	212	15	EFO_0005653
Disease	vital capacity	DENND2A DSCR4 ZZEF1 GFPT1 CARNS1 QSOX2 CHCHD7 TCP11 JADE2 ARFGEF2 PCDHA5 CHD7 CHAMP1 JMJD1C THBS1 CEP83 PATJ DKK3	3.69e-03	1236	212	18	EFO_0004312
Disease	serum albumin measurement	DOCK4 NAT2 ZZEF1 HNF4A DHODH BSN SPTY2D1 QSOX2 GRIK5 JMJD1C RSBN1L	3.89e-03	592	212	11	EFO_0004535
Disease	diabetic retinopathy (biomarker_via_orthology)	PIK3CG TIMM44 THBS1	4.16e-03	45	212	3	DOID:8947 (biomarker_via_orthology)
Disease	emphysema imaging measurement	ERCC4 ANKRD12 DNAH5 GRIK5 CHTF18	4.16e-03	146	212	5	EFO_0007626
Disease	sleep duration, low density lipoprotein cholesterol measurement	ATXN7L2 DHODH PLCG1 DOCK7	4.25e-03	91	212	4	EFO_0004611, EFO_0005271
Disease	rostral middle frontal gyrus volume measurement	BCL2L10 MAPK6	4.42e-03	14	212	2	EFO_0010328
Disease	Hermansky-Pudlak syndrome (implicated_via_orthology)	VPS33A HPS5	4.42e-03	14	212	2	DOID:3753 (implicated_via_orthology)
Disease	neutrophil count, eosinophil count	RPN1 PSMD3 HNF4A CHD7 JMJD1C MAPK4	4.53e-03	213	212	6	EFO_0004833, EFO_0004842
Disease	red blood cell density measurement	RALGAPA1 SLK DENND4A RPN1 BCAS3 DPP8 HNF4A DENND2B KCNA4 PNPLA1 PLCL2 ARFGEF2 JMJD1C BCL11B	4.77e-03	880	212	14	EFO_0007978
Disease	platelet storage pool deficiency (implicated_via_orthology)	DOCK7 HPS5	5.07e-03	15	212	2	DOID:2223 (implicated_via_orthology)
Disease	infant head circumference	PLCG1 ARFGEF2	5.07e-03	15	212	2	EFO_0004577
Disease	polyunsaturated fatty acids to total fatty acids percentage	NAT2 JMJD1C DOCK7	5.59e-03	50	212	3	EFO_0022303
Disease	colorectal cancer (is_marker_for)	ERCC4 ERCC6 ERCC6L PLCG1 THBS1	5.64e-03	157	212	5	DOID:9256 (is_marker_for)
Disease	low density lipoprotein cholesterol measurement, alcohol consumption measurement	NAT2 HNF4A SPTY2D1 DOCK7	5.73e-03	99	212	4	EFO_0004611, EFO_0007878
Disease	Tremor, Rubral	CACNB4 CP	5.77e-03	16	212	2	C0750940
Disease	Ataxia, Appendicular	CACNB4 CP	5.77e-03	16	212	2	C0750937
Disease	Ataxia, Motor	CACNB4 CP	5.77e-03	16	212	2	C0278161
Disease	Ataxia, Sensory	CACNB4 CP	5.77e-03	16	212	2	C0240991
Disease	Abnormal coordination	CACNB4 CP	5.77e-03	16	212	2	C0520966
Disease	Ataxia, Truncal	CACNB4 CP	5.77e-03	16	212	2	C0427190
Disease	polyunsaturated fatty acids to monounsaturated fatty acids ratio	NAT2 JMJD1C DOCK7	5.91e-03	51	212	3	EFO_0022302
Disease	low density lipoprotein cholesterol measurement, alcohol drinking	NAT2 HNF4A SPTY2D1 DOCK7	6.36e-03	102	212	4	EFO_0004329, EFO_0004611
Disease	alcohol consumption measurement, high density lipoprotein cholesterol measurement	HNF4A SPATS2 DAGLB DOCK7 CDH16	6.42e-03	162	212	5	EFO_0004612, EFO_0007878
Disease	Muscle hypotonia	RALGAPA1 INTS1	6.51e-03	17	212	2	C0026827
Disease	heart disease (biomarker_via_orthology)	CP THBS1	6.51e-03	17	212	2	DOID:114 (biomarker_via_orthology)
Disease	oral motor function measurement	GSX1 MON1B	6.51e-03	17	212	2	EFO_0021793
Disease	interleukin 1 receptor antagonist measurement	PSMD3 KCNIP4 SLC26A11	6.58e-03	53	212	3	EFO_0004754
Disease	free cholesterol to total lipids in small LDL percentage	NAT2 JMJD1C DOCK7	6.58e-03	53	212	3	EFO_0022286
Disease	circadian rhythm	NOL4 PDIA2 SPTY2D1 PATJ PHACTR1	6.59e-03	163	212	5	EFO_0004354
Disease	sleep duration, triglyceride measurement	NAT2 ALK JMJD1C DOCK7	6.81e-03	104	212	4	EFO_0004530, EFO_0005271
Disease	monocyte percentage of leukocytes	GAD2 DENND4A RPN1 PSMD3 BCL6 DPP8 DAGLB TCP11 JADE2 ZYG11B CHD7 JMJD1C	6.89e-03	731	212	12	EFO_0007989

Protein segments in the cluster

Peptide	Gene	Start	Entry
RFSRDDVIGEVMVPL	SYT11	251	Q9BT88
PLRDMFLSDEDSVSR	USH1G	271	Q495M9
LMLLELFDSEDPRER	PPP2R5B	196	Q15173
VVKRLNFRSEEMEEP	CHTF18	106	Q8WVB6
LDISPAMLDEAVDRE	BUD23	81	O43709
EDDFPRRLSESMEDL	ARHGEF18	6	Q6ZSZ5
FMPTAAERDEILRAV	CHCHD7	66	Q9BUK0
RTVTERLLDEMFDST	CFAP54	391	Q96N23
SSPAMRRLTVDDFEI	AURKC	31	Q9UQB9
MDRNFDTLDLPKRTE	ARVCF	636	O00192
FSSPMEAELVRRILS	CTAG2	96	O75638
LEELRRVVAALPESM	CTAGE4	16	Q8IX94
LEELRRVVAALPESM	CTAGE6	16	Q86UF2
LEELRRVVAALPESM	CTAGE8	16	P0CG41
LEELRRVVAALPESM	CTAGE15	16	A4D2H0
MADPLRERTELLLAD	BCL2L10	11	Q9HD36
RSGPFEVRADLEESM	ATG14	391	Q6ZNE5
RPSSILMEARVDLID	ACR	191	P10323
PRDFTRMQDIPEETE	ARHGEF2	961	Q92974
LRVMTFDDDIRVPFG	ARMC6	246	Q6NXE6
VVVLFMRSDDSRELI	GRM3	271	Q14832
ETEEPLSARRLTENM	GRAMD4	191	Q6IC98
AAFPDTSMEAIRLIR	ARFGEF2	1281	Q9Y6D5
DEAVAAPLVETMLRR	CARNS1	371	A5YM72
ERFEAVMAVLRELPR	ADCK5	461	Q3MIX3
LETPMRERFRNLDEE	CEP83	126	Q9Y592
MVPEERRVGLSSDET	DNHD1	1	Q96M86
MSLIILTRDDEPRIF	DSCR4	1	P56555
TASEMERVRLVRFDP	AMBRA1	176	Q9C0C7
MPVDRLETLSTRDFI	ANKRD12	1421	Q6UB98
RAEMDEVERFQPLLD	DIAPH1	286	O60610
RFIRQMDDEDTLLPR	DENND2B	976	P78524
RLADAMAESPSRDVV	BCAS3	861	Q9H6U6
ENSPIERRSLMTSDE	CACNB4	446	O00305
RIMDFARSTDDRGEP	CHD7	886	Q9P2D1
EFEKLMSREPETERV	CHD7	931	Q9P2D1
PKREEMVLDDSARFL	ATP2A1	571	O14983
MAALERRVPSLDDFA	ATXN7L2	11	Q5T6C5
ERLSEGEFTPEMQVR	ASXL2	341	Q76L83
SDFLERMPREEATEI	POLL	381	Q9UGP5
STPSARRDLAEEIVM	DENND4A	1196	Q7Z401
MDDRELIPFVVDEQR	QRICH2	261	Q9H0J4
PDRELRTVRQTMIDF	QSOX2	161	Q6ZRP7
SDTDVSMPLVEERHR	C9orf64	136	Q5T6V5
VRSIMDEAPLTDVRD	RABEP2	551	Q9H5N1
SLSEEMELEFRKRSP	P3H1	131	Q32P28
DIMPSGRSRLLEDFR	PUM2	701	Q8TB72
DMLIIEEDQTRPRSS	YOD1	116	Q5VVQ6
EIDSLVDSDFRMVLR	LTN1	56	O94822
ERTLDRLLDSMEQDP	MON1B	226	Q7L1V2
LLLEDNIRMFTTAPD	CP	591	P00450
VMRTPTEILELFLDD	ERCC6	606	P0DP91
DDEIRMINEFPRVAS	DCHS1	3041	Q96JQ0
PSLRTLEDNEERMSR	GAD2	511	Q05329
VAIREAEARPFEVLM	LZTR1	511	Q8N653
DPLEDRSIALVNFMR	MAGEE2	86	Q8TD90
VLSDIDEMSRRRPEI	INTS1	2066	Q8N201
DEMSRRRPEILSFFS	INTS1	2071	Q8N201
TSPSEELLLEDQMRR	MCOLN3	26	Q8TDD5
SRRMLEEERVPVTFV	LMOD3	81	Q0VAK6
EDKDELLRVMPSFVS	MAPK4	251	P31152
RPLESDVFIEDRAEM	HEBP2	121	Q9Y5Z4
EELERKAFMEPLRSV	JMJD1C	956	Q15652
MERASSRVGETEELP	KIAA1109	3631	Q2LD37
VSERPRSSTDALIEM	HERC1	146	Q15751
LFRLMDSTVPDEIQE	HERC1	826	Q15751
DPLVLFESESLRMVL	HPS5	626	Q9UPZ3
PARAAELTDEDFMRR	BSN	831	Q9UPA5
EMLTLLLERPTDDSV	CWC22	276	Q9HCG8
DPVFEDVARVALMRL	EDEM2	211	Q9BV94
DGSSMIPVRLLRDFE	EID2B	101	Q96D98
PELAEMSRVSIRILD	HNF4A	256	P41235
QDEETLLSFMRDPSL	JADE2	571	Q9NQC1
RAVLEPRDFALDVEM	FBLN2	1146	P98095
IAPSDDARRLTVMSL	FLNB	2281	O75369
PFDSIMERLTLRRID	AK8	381	Q96MA6
SDMVRGIPVFTEDRD	PLXNA4	416	Q9HCM2
LRFDPDLMGRDIDII	NXF5	126	Q9H1B4
DFLEQILTFSPMDRL	MAPK6	291	Q16659
ILTFSPMDRLTAEEA	MAPK6	296	Q16659
LRLPSERLDFSMAEA	PRPH	71	P41219
VVRRVDREELSVMPF	PDE8A	161	O60658
LERVFVRMDQVLPDS	PCED1A	161	Q9H1Q7
RPIRDLDDVRFAMEA	DNAH8	1111	Q96JB1
IDVMDRLSPSILESF	FRYL	731	O94915
MPRSFLVDSLVLREA	GSX1	1	Q9H4S2
SVEDELEMATVRHRP	KCNIP4	56	Q6PIL6
SLDSLREEIEQMRRP	COL11A2	1546	P13942
AVDALRDLAPRMLET	PNPLA1	31	Q8N8W4
LLRDFPDELRADIAM	KCNH4	531	Q9UQ05
QMTRLEAEFVRREAP	LRP3	536	O75074
EEEFPELARRPASML	GDPD5	286	Q8WTR4
VREMRSAVLSEPVLF	FAHD1	31	Q6P587
AGRPLELSDFRMEES	TMPO	371	P42167
MSRPERLLFIIDGFD	NLRP5	351	P59047
DALDMTFGLTDRPRL	PDIA2	196	Q13087
EQRLFILESRMPDSR	PCDHA5	136	Q9Y5H7
EMRADVASLRALSPE	LBX2	146	Q6XYB7
LPDTDMDSLREARRE	NSUN6	431	Q8TEA1
PSDLRRSVLEDMEDS	HUWE1	3066	Q7Z6Z7
RRNRPLLDFVSMEEL	PHF14	186	O94880
DREARPSRMEILSTL	PLEKHH2	1096	Q8IVE3
PETVVMVFRIRDRDS	PCDHB12	361	Q9Y5F1
RTPLFDQIIDMLRVE	ALDH18A1	626	P54886
SADPELALVLRVFME	PIPSL	696	A2A3N6
TFDLLEMDRLERPLV	PANK4	406	Q9NVE7
LMAASSEDDIDRRPI	PHACTR1	46	Q9C0D0
EVERLAAMRSDSLVP	PHACTR1	86	Q9C0D0
RLSLMEPESEFRDID	PLIN1	406	O60240
MLRDSEAEVTEEDPR	C4orf50	1	Q6ZRC1
ELDRLSTSEVVMFLE	ICE1	1166	Q9Y2F5
APELVERVQSVDFMR	KLHL14	271	Q9P2G3
IDSPAMDFSRRLREL	BCL11B	356	Q9C0K0
RTPLSEAEFEEIMNR	CPSF6	406	Q16630
DPEDISITELYRLME	DOCK4	171	Q8N1I0
RFPERFMDDIAALVS	DOCK7	1036	Q96N67
PLRILLEEMEQADFT	DNAH17	291	Q9UFH2
IDESIAPLFEIRMEL	DNAH17	891	Q9UFH2
FLRQMDDEDSILPRK	DENND2A	846	Q9ULE3
ITPERTDIARLLDMD	EIF3A	331	Q14152
LELESSMAESRLRAP	DBF4B	11	Q8NFT6
PDILMRALDSVVSDR	DAGLB	641	Q8NCG7
SEDIRLSPFMADIRD	FLNA	651	P21333
MEAFQELRKPSARLE	CHAMP1	1	Q96JM3
QVFSEKRRPEEEMAL	FRMPD2	551	Q68DX3
RQPLEELAAEDRFML	FMNL3	701	Q8IVF7
LFIPVEDDVMERQRL	DPP8	411	Q6V1X1
VRERPMALEAELALT	IFNL2	91	Q8IZJ0
TEMERTLALLAFDSP	GID8	141	Q9NWU2
RLVPLASDMIFAREV	ELMO3	106	Q96BJ8
RDIIDTPMDFGTVRE	BRWD1	1351	Q9NSI6
LLFSDEEFRDVRMPV	BCL6	206	P41182
LFTLEPRTIEDFESM	NAT2	191	P11245
FTREELAMRLDLTEA	ARX	356	Q96QS3
TRFEREQRPMEELSE	FMNL1	766	O95466
VRDPAMDRSLRSVFV	CSTF2T	6	Q9H0L4
LPEDFMESLKEDRTT	PTK2B	136	Q14289
MVTRRALFPGDSEID	CDK2	196	P24941
AFVLAMLSRVEPSDR	DDX19A	146	Q9NUU7
VLEEPFVMFRKSDRT	GRIK3	441	Q13003
ETLSVRMLDDSRDPT	GRIK5	186	Q16478
SMTVRELFEELDRPA	DHX37	806	Q8IY37
LLDQIPEMFADTRET	SEC24C	601	P53992
FEEEMDTRPKVSSLL	SLC12A6	136	Q9UHW9
RSLTEEMALREPAAA	DKK3	326	Q9UBP4
MLTAIDADLEPAFRL	CDH16	471	O75309
FRIDAILEEMSSTPL	DNAH5	826	Q8TE73
MEASRRFPEAEALSP	ERCC6L	1	Q2NKX8
IAEPMRRSVSEAALA	LIPE	846	Q05469
LDDPEDAVFVRSMKR	LRRC72	236	A6NJI9
FSLVDQRELEPLREM	MOB3C	196	Q70IA8
ASMLDITRDPLREIA	PTPN13	511	Q12923
ITRDPLREIALETAM	PTPN13	516	Q12923
DEDLMRQTEGRVPVF	MED8	86	Q96G25
LPLFREVDMVDITED	NTMT1	81	Q9BV86
SIGPEEMRRLEDLEY	FNDC8	306	Q8TC99
TSEPREMLFEDRTRA	RSBN1L	556	Q6PCB5
RVPLRDLSVTLDVFM	SZT2	1606	Q5T011
TEDEETMYLRRPEGI	STEEP1	71	Q9H5V9
PPLSRMNREELEDSF	RPGRIP1	36	Q96KN7
YVEDEMARLPDRLSV	SMCHD1	681	A6NHR9
VDAVMLELERPLTES	SLK	116	Q9H2G2
IAMAVFPLRAERAES	TMEM140	166	Q9NV12
LEETLPERMREELSA	SYNM	956	O15061
ELPVMVELASDFLDR	GFPT1	411	Q06210
SDFRLPTEEEIRAMV	TAF1	866	P21675
TPSAELMEVRRLFLS	NBEA	856	Q8NFP9
LPELAMVRFVVLDDD	PLCL2	821	Q9UPR0
VDATRVPMDERFRTL	PTPN14	886	Q15678
LLPRARFQDSDMLEV	DHODH	66	Q02127
EAARAVPELRMLDDI	PPP1R16A	201	Q96I34
LILDDSVEMEIRPRF	RPN1	306	P04843
VLDIPERSQREMFFT	SIMC1	696	Q8NDZ2
EILTDMSRPVELSDR	CCT4	146	P50991
LSRLRSFPMRAEDLE	PPP1R3G	161	B7ZBB8
FRRILLAEVPTMAVE	POLR1C	76	O15160
MLDFIRDEPLDSLAS	MROH2B	786	Q7Z745
KTEDSLMPEEEFLRR	SF3A1	686	Q15459
PMTAEELREREFLER	SPTY2D1	196	Q68D10
EEMLSSVIPDSRREN	MSANTD4	161	Q8NCY6
RLFVDENLDRMVPIS	NOL4	416	O94818
TPFRLSEKDRMELLE	RSRP1	166	Q9BUV0
RDARPDTDMRPDTDT	SLC6A18	601	Q96N87
ATDPAMLRRATEDVR	SNED1	121	Q8TER0
EDMDVERALRAARLP	B4GALNT4	866	Q76KP1
RRIPSEEASQMDLLD	ALK	291	Q9UM73
SFMREERVREELPLD	CCDC15	681	Q0P6D6
TRTSEVMARELPELE	C11orf16	296	Q9NQ32
DMVITRPDIGFLRTD	CLVS2	36	Q5SYC1
DELEFTRRGLVTPRM	PIK3CG	171	P48736
MERQEESLSARPALE	SELENOS	1	Q9BQE4
EEDIERASDPLMSRD	RAPGEF2	91	Q9Y4G8
MDGVREEDLAPFSLR	RNF213	2281	Q63HN8
NEEFPETLLMDRTRL	TCP11	306	Q8WWU5
LEDPESAMLDTLDRT	SPATS2	161	Q86XZ4
EDRPDFLTVEQRMRA	ZAP70	581	P43403
DRPDAFELETRMDQV	STK35	516	Q8TDR2
LELFMRVLESFPTES	ZYG11B	541	Q9C0D3
DISETDFRRFQMIPL	THBS1	951	P07996
RETLLDSRVMELFFT	XPO4	266	Q9C0E2
GEITIPMRSRIREFD	YIPF6	36	Q96EC8
RRQEEDFLLPETTVM	ZSCAN5DP	191	P0CG00
EEPMDTEADLQFRPR	PSMD3	136	O43242
PDLMDEFIAERLRSG	RALGAPA1	836	Q6GYQ0
FPAMEALREEILSRA	SLC26A11	491	Q86WA9
FLTPRLQEMDEEREI	PATJ	856	Q8NI35
AFPLMGETQERERVL	PSD2	371	Q9BQI7
PVIARADSLTMEERE	SEPTIN12	191	Q8IYM1
FVVEPERMLTATESR	TMEM79	361	Q9BSE2
SRENMSDVRELTPEF	WDFY4	2681	Q6ZS81
ASMERPSAEERVLVR	ZNF276	101	Q8N554
FMLSFLRDPLREIEE	PLCG1	276	P19174
EVLRDFPELTMEVDG	ATP6V1A	286	P38606
GTFRMVPEEEQELRA	RLBP1	6	P12271
REMREPFLNLEVEAL	SMCO2	326	A6NFE2
MTDLRTLDTFLRSEE	TMEM209	236	Q96SK2
EALFSEDMPLRDVIV	ZSCAN4	141	Q8NAM6
RVMAAFPELSDLARL	ZC3H12D	496	A2A288
MSEVLTEILRVDPAF	TIMM44	296	O43615
LSFRSMEEARLVPTV	ZZEF1	1536	O43149
MQERDEFSRIPRTIS	ZNF835	51	Q9Y2P0
SMLLDVAVSPDDRFI	WDR4	146	P57081
IETMEVPRRRFSDLT	UBXN10	241	Q96LJ8
FFVRPRLELMDIIAE	VPS33A	81	Q96AX1
PFSQMSELLTRAEER	WASF1	256	Q92558
VDMREFRSELPSLIH	ERCC4	686	Q92889
FEDDMRTLREKRTEP	TRAPPC10	201	P48553
PALVRLLFETMEREG	TTC22	541	Q5TAA0
DFVERFLPREMDILA	TSSK2	51	Q96PF2
LRVMARLEPDAEEAA	TRPM4	596	Q8TD43
DVALPALLDSDEERM	TMEM87A	531	Q8NBN3
RVAEEMTFFPRDEKI	TOR1B	306	O14657
LETLPEFRDDRDLVM	KCNA4	326	P22459
SSSFVLDPEELERLM	MYOM2	991	P54296
LEPEELDRVALSNRM	NDN	171	Q99608