Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphotyrosine residue binding

RASA1 ZAP70 VAV1

4.40e-0551273GO:0001784
GeneOntologyMolecularFunctionprotein phosphorylated amino acid binding

RASA1 ZAP70 VAV1

1.09e-0469273GO:0045309
GeneOntologyMolecularFunctionhistone modifying activity

RIOX2 MST1 RSBN1 EHMT2

2.40e-04229274GO:0140993
GeneOntologyMolecularFunctionphosphoprotein binding

RASA1 ZAP70 VAV1

5.18e-04117273GO:0051219
GeneOntologyMolecularFunctionhistone demethylase activity

RIOX2 RSBN1

7.99e-0431272GO:0032452
GeneOntologyMolecularFunctionprotein demethylase activity

RIOX2 RSBN1

8.52e-0432272GO:0140457
GeneOntologyMolecularFunctiondemethylase activity

RIOX2 RSBN1

1.61e-0344272GO:0032451
GeneOntologyMolecularFunctionnon-membrane spanning protein tyrosine kinase activity

JAK1 ZAP70

1.76e-0346272GO:0004715
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

RIOX2 RSBN1 COQ7

2.22e-03194273GO:0016705
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

JAK1 MST1 IRAK1 PIP5K1B ZAP70

2.35e-03709275GO:0016773
GeneOntologyMolecularFunctiontranscription corepressor binding

EHMT2 PHF12

2.87e-0359272GO:0001222
GeneOntologyMolecularFunctionkinase activity

JAK1 MST1 IRAK1 PIP5K1B ZAP70

3.24e-03764275GO:0016301
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

RIOX2 RSBN1

3.47e-0365272GO:0016706
GeneOntologyMolecularFunctionreceptor tyrosine kinase binding

MST1 RASA1

6.55e-0390272GO:0030971
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

JAK1 MST1 IRAK1 PIP5K1B ZAP70

7.71e-03938275GO:0016772
GeneOntologyMolecularFunctiondioxygenase activity

RIOX2 RSBN1

7.73e-0398272GO:0051213
GeneOntologyMolecularFunctionprotein kinase activity

JAK1 MST1 IRAK1 ZAP70

8.18e-03600274GO:0004672
GeneOntologyMolecularFunctioncytokine receptor binding

JAK1 IRAK1 LIFR

9.28e-03324273GO:0005126
HumanPhenoNephrotic syndrome

JAK1 IRAK1 RASA1 ZAP70

1.74e-0513974HP:0000100
HumanPhenoAbnormal renal cortex morphology

JAK1 IRAK1 RASA1 ZAP70 COQ7

1.79e-0532075HP:0011035
HumanPhenoGlomerulopathy

JAK1 IRAK1 RASA1 ZAP70

4.06e-0517274HP:0100820
HumanPhenoAbnormal eosinophil morphology

JAK1 MST1 ZAP70

9.10e-057273HP:0001879
HumanPhenoPleural effusion

MST1 IRAK1 RASA1

1.83e-049173HP:0002202
HumanPhenoAbnormal renal glomerulus morphology

JAK1 IRAK1 RASA1 ZAP70

2.86e-0428374HP:0000095
HumanPhenoAbnormal renal corpuscle morphology

JAK1 IRAK1 RASA1 ZAP70

2.86e-0428374HP:0031263
HumanPhenoGlomerulonephritis

JAK1 IRAK1 ZAP70

3.31e-0411173HP:0000099
HumanPhenoInflammation of the large intestine

JAK1 MST1 ZAP70

4.06e-0411973HP:0002037
DomainSH2

JAK1 RASA1 ZAP70 VAV1

2.09e-05110284SM00252
DomainSH2

JAK1 RASA1 ZAP70 VAV1

2.17e-05111284PS50001
DomainSH2

JAK1 RASA1 ZAP70 VAV1

2.25e-05112284IPR000980
Domain-

JAK1 RASA1 ZAP70 VAV1

2.25e-051122843.30.505.10
DomainGAIN_dom_N

ADGRB2 ADGRL2

1.18e-0411282IPR032471
DomainGAIN

ADGRB2 ADGRL2

1.18e-0411282PF16489
DomainKringle

MST1 KREMEN2

2.91e-0417282IPR000001
DomainKringle

MST1 KREMEN2

2.91e-0417282PF00051
DomainKRINGLE_1

MST1 KREMEN2

2.91e-0417282PS00021
DomainKringle_CS

MST1 KREMEN2

2.91e-0417282IPR018056
DomainKR

MST1 KREMEN2

2.91e-0417282SM00130
DomainKRINGLE_2

MST1 KREMEN2

2.91e-0417282PS50070
DomainFA58C

CNTNAP3 CNTNAP3B

4.47e-0421282SM00231
DomainFA58C_3

CNTNAP3 CNTNAP3B

4.47e-0421282PS50022
DomainFA58C_1

CNTNAP3 CNTNAP3B

4.47e-0421282PS01285
DomainFA58C_2

CNTNAP3 CNTNAP3B

4.47e-0421282PS01286
DomainSH2

RASA1 ZAP70 VAV1

4.56e-04101283PF00017
DomainF5_F8_type_C

CNTNAP3 CNTNAP3B

5.86e-0424282PF00754
DomainFA58C

CNTNAP3 CNTNAP3B

5.86e-0424282IPR000421
DomainHormR

ADGRB2 ADGRL2

6.36e-0425282SM00008
DomainHRM

ADGRB2 ADGRL2

8.00e-0428282PF02793
DomainFibrinogen_a/b/g_C_dom

CNTNAP3 CNTNAP3B

1.05e-0332282IPR002181
DomainFIBRINOGEN_C_2

CNTNAP3 CNTNAP3B

1.05e-0332282PS51406
DomainKringle-like

MST1 KREMEN2

1.05e-0332282IPR013806
DomainFIBRINOGEN_C_1

CNTNAP3 CNTNAP3B

1.05e-0332282PS00514
DomainGPS

ADGRB2 ADGRL2

1.18e-0334282SM00303
DomainGPS

ADGRB2 ADGRL2

1.25e-0335282PF01825
DomainGPS

ADGRB2 ADGRL2

1.32e-0336282PS50221
DomainGPS

ADGRB2 ADGRL2

1.40e-0337282IPR000203
DomainLAM_G_DOMAIN

CNTNAP3 CNTNAP3B

1.47e-0338282PS50025
DomainG_PROTEIN_RECEP_F2_1

ADGRB2 ADGRL2

1.63e-0340282PS00649
DomainLaminin_G_2

CNTNAP3 CNTNAP3B

1.63e-0340282PF02210
DomainG_PROTEIN_RECEP_F2_3

ADGRB2 ADGRL2

1.63e-0340282PS50227
DomainGPCR_2_extracellular_dom

ADGRB2 ADGRL2

1.63e-0340282IPR001879
DomainLamG

CNTNAP3 CNTNAP3B

1.97e-0344282SM00282
DomainG_PROTEIN_RECEP_F2_2

ADGRB2 ADGRL2

2.54e-0350282PS00650
Domain7tm_2

ADGRB2 ADGRL2

2.54e-0350282PF00002
Domain-

SEMA3F CD274 LIFR NCR1 FCRL6

2.77e-036632852.60.40.10
DomainIG

SEMA3F CD274 NCR1 FCRL6

3.39e-03421284SM00409
DomainIg_sub

SEMA3F CD274 NCR1 FCRL6

3.39e-03421284IPR003599
DomainLaminin_G

CNTNAP3 CNTNAP3B

3.40e-0358282IPR001791
DomainIg-like_fold

SEMA3F CD274 LIFR NCR1 FCRL6

3.63e-03706285IPR013783
DomainGPCR_2-like

ADGRB2 ADGRL2

3.64e-0360282IPR017981
DomainGPCR_2_secretin-like

ADGRB2 ADGRL2

3.64e-0360282IPR000832
DomainG_PROTEIN_RECEP_F2_4

ADGRB2 ADGRL2

3.76e-0361282PS50261
DomainEGF

CNTNAP3 CNTNAP3B FCGBP

5.11e-03235283SM00181
DomainIG_LIKE

SEMA3F CD274 NCR1 FCRL6

5.86e-03491284PS50835
DomainEGF-like_dom

CNTNAP3 CNTNAP3B FCGBP

6.00e-03249283IPR000742
DomainIg-like_dom

SEMA3F CD274 NCR1 FCRL6

6.37e-03503284IPR007110
DomainTyrKc

JAK1 ZAP70

7.66e-0388282SM00219
DomainTyr_kinase_cat_dom

JAK1 ZAP70

7.66e-0388282IPR020635
DomainGalactose-bd-like

CNTNAP3 CNTNAP3B

8.70e-0394282IPR008979
DomainPROTEIN_KINASE_TYR

JAK1 ZAP70

9.24e-0397282PS00109
DomainTyr_kinase_AS

JAK1 ZAP70

9.24e-0397282IPR008266
PathwayWP_PDGF_PATHWAY

JAK1 RASA1 VAV1

2.72e-0540213M39555
PathwayBIOCARTA_TCR_PATHWAY

RASA1 ZAP70 VAV1

3.15e-0542213MM1504
PathwayBIOCARTA_TCR_PATHWAY

RASA1 ZAP70 VAV1

3.63e-0544213M19784
PathwayWP_INTERFERON_TYPE_I_SIGNALING

JAK1 ZAP70 VAV1

6.73e-0554213M39435
PathwayWP_PROLACTIN_SIGNALING

JAK1 ZAP70 VAV1

1.87e-0476213M39601
PathwayREACTOME_IL_6_TYPE_CYTOKINE_RECEPTOR_LIGAND_INTERACTIONS

JAK1 LIFR

2.84e-0417212M27612
PathwayKEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY

ZAP70 VAV1

3.56e-0419212M47733
PathwayWP_CANCER_IMMUNOTHERAPY_BY_PD1_BLOCKADE

CD274 ZAP70

5.25e-0423212M39843
PathwayREACTOME_INTERLEUKIN_6_FAMILY_SIGNALING

JAK1 LIFR

5.72e-0424212M27604
PathwayREACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK

IRAK1 PIP5K1B VAV1

6.00e-04113213MM14783
PathwayREACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK

IRAK1 PIP5K1B VAV1

6.81e-04118213M713
PathwayBIOCARTA_EGF_PATHWAY

JAK1 RASA1

7.25e-0427212M1909
PathwayKEGG_MEDICUS_REFERENCE_IL6_FAMILY_TO_JAK_STAT_SIGNALING_PATHWAY

JAK1 LIFR

7.25e-0427212M47906
PathwayWP_T_CELL_RECEPTOR_AND_COSTIMULATORY_SIGNALING

RASA1 ZAP70

7.81e-0428212M39632
PathwayBIOCARTA_EGF_PATHWAY

JAK1 RASA1

7.81e-0428212MM1386
PathwayBIOCARTA_PDGF_PATHWAY

JAK1 RASA1

7.81e-0428212M2529
PathwayBIOCARTA_PDGF_PATHWAY

JAK1 RASA1

8.38e-0429212MM1452
PathwayWP_PDGFRBETA_PATHWAY

JAK1 RASA1

8.38e-0429212M39616
PathwayKEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY

NCR1 ZAP70 VAV1

1.05e-03137213M5669
Pubmed

Cooperation and selectivity of the two Grb2 binding sites of p52Shc in T-cell antigen receptor signaling to Ras family GTPases and Myc-dependent survival.

RASA1 ZAP70 VAV1

1.33e-071328315688026
Pubmed

Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation.

RASA1 ZAP70 VAV1

2.11e-071528310790433
Pubmed

The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.

CNTNAP3 CNTNAP3B

6.25e-07228231150793
Pubmed

Endotoxin Tolerant Dendritic Cells Suppress Inflammatory Responses in Splenocytes via Interleukin-1 Receptor Associated Kinase (IRAK)-M and Programmed Death-Ligand 1 (PDL-1).

CD274 IRAK1

6.25e-07228229995830
Pubmed

Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.

CNTNAP3 CNTNAP3B

6.25e-07228226807827
Pubmed

The protein tyrosine kinase ZAP-70 can associate with the SH2 domain of proto-Vav.

ZAP70 VAV1

6.25e-0722827798261
Pubmed

A quantitative protein interaction network for the ErbB receptors using protein microarrays.

JAK1 RASA1 ZAP70 VAV1

8.19e-079028416273093
Pubmed

IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion.

JAK1 CD274

1.87e-06328231305264
Pubmed

Protein-tyrosine kinase Pyk2 is involved in interleukin-2 production by Jurkat T cells via its tyrosine 402.

ZAP70 VAV1

3.75e-06428210867021
Pubmed

Two distinct regions of the CD28 intracytoplasmic domain are involved in the tyrosine phosphorylation of Vav and GTPase activating protein-associated p62 protein.

RASA1 VAV1

3.75e-0642829620604
Pubmed

SHP2 is a downstream target of ZAP70 to regulate JAK1/STAT3 and ERK signaling pathways in mouse embryonic stem cells.

JAK1 ZAP70

3.75e-06428220846526
Pubmed

T-cell receptor antagonists induce Vav phosphorylation by selective activation of Fyn kinase.

ZAP70 VAV1

3.75e-06428211005864
Pubmed

Zap70 functions to maintain stemness of mouse embryonic stem cells by negatively regulating Jak1/Stat3/c-Myc signaling.

JAK1 ZAP70

3.75e-06428220641039
Pubmed

Binding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins.

RASA1 ZAP70

3.75e-0642827760813
Pubmed

CDC25A, VAV1, TP73, BRCA1 and ZAP70 gene overexpression correlates with radiation response in colorectal cancer.

ZAP70 VAV1

6.24e-06528221344162
Pubmed

Differential expression and molecular associations of Syk in systemic lupus erythematosus T cells.

ZAP70 VAV1

6.24e-06528219018007
Pubmed

T cell activation-induced CrkII binding to the Zap70 protein tyrosine kinase is mediated by Lck-dependent phosphorylation of Zap70 tyrosine 315.

ZAP70 VAV1

6.24e-06528216339550
Pubmed

Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling.

ZAP70 VAV1

6.24e-06528210662792
Pubmed

Association of CD45 with Lck and components of the Ras signalling pathway in pervanadate-treated mouse T-cell lines.

RASA1 VAV1

6.24e-0652828570203
Pubmed

Interactions between the protein-tyrosine kinase ZAP-70, the proto-oncoprotein Vav, and tubulin in Jurkat T cells.

ZAP70 VAV1

9.36e-0662828530437
Pubmed

In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development.

CNTNAP3 CNTNAP3B

9.36e-06628234143959
Pubmed

Recruitment and activation of PLCgamma1 in T cells: a new insight into old domains.

ZAP70 VAV1

9.36e-06628216467851
Pubmed

The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins.

ADGRB2 ADGRL2

9.36e-06628210964907
Pubmed

SOCS-1 localizes to the microtubule organizing complex-associated 20S proteasome.

JAK1 VAV1

1.31e-05728215456882
Pubmed

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b.

ZAP70 VAV1

1.31e-05728210646608
Pubmed

When killers become thieves: Trogocytosed PD-1 inhibits NK cells in cancer.

CD274 NCR1

1.31e-05728235417234
Pubmed

Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2.

ZAP70 VAV1

1.31e-0572829047237
Pubmed

Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells.

ZAP70 VAV1

1.31e-05728212084069
Pubmed

Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells.

ZAP70 VAV1

1.31e-05728221725281
Pubmed

Phosphorylation of the linker for activation of T-cells by Itk promotes recruitment of Vav.

ZAP70 VAV1

1.31e-05728212186560
Pubmed

Regulation of NK cell-mediated cytotoxicity by the adaptor protein 3BP2.

ZAP70 VAV1

1.74e-05828211390470
Pubmed

Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells.

ZAP70 VAV1

1.74e-05828211368773
Pubmed

The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation.

ZAP70 VAV1

1.74e-05828211133830
Pubmed

Identification of substrates of human protein-tyrosine phosphatase PTPN22.

ZAP70 VAV1

2.24e-05928216461343
Pubmed

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation.

ZAP70 VAV1

2.24e-0592829489702
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

JAK1 IRAK1 RSBN1 ADGRL2 EHMT2 PHF12 VAV1

2.25e-05111628731753913
Pubmed

Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.

RASA1 ZAP70 VAV1

2.80e-057328324728074
Pubmed

Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCĪ² Kinase Activity.

ZAP70 VAV1

2.80e-051028226936881
Pubmed

Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors.

RASA1 ZAP70 VAV1

3.28e-057728322973453
Pubmed

Interchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular function.

ZAP70 VAV1

3.42e-051128222732588
Pubmed

Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells.

RASA1 VAV1

3.42e-051128220598684
Pubmed

CD4 cross-linking (CD4XL) induces RAS activation and tumor necrosis factor-alpha secretion in CD4+ T cells.

ZAP70 VAV1

4.10e-05122829269777
Pubmed

CUEDC2, a novel interacting partner of the SOCS1 protein, plays important roles in the leukaemogenesis of acute myeloid leukaemia.

JAK1 RASA1 VAV1

4.73e-058728329991678
Pubmed

p190RhoGAP Filters Competing Signals to Resolve Axon Guidance Conflicts.

SEMA3F RASA1

5.65e-051428230902550
Pubmed

Cell adhesion molecule contactin-associated protein 3 is expressed in the mouse basal ganglia during early postnatal stages.

CNTNAP3 CNTNAP3B

8.44e-051728226389685
Pubmed

FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.

CNTNAP3 CNTNAP3B

1.43e-042228226494785
Pubmed

Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1.

RASA1 VAV1

1.71e-042428220624904
Pubmed

Modulation of HIV pathogenesis and T-cell signaling by HIV-1 Nef.

ZAP70 VAV1

2.17e-042728222844345
Pubmed

Genetic polymorphisms, their allele combinations and IFN-beta treatment response in Irish multiple sclerosis patients.

JAK1 CD274

2.17e-042728219604093
Pubmed

Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications.

RASA1 VAV1

2.33e-042828218067320
Pubmed

The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.

ADGRB2 ADGRL2

2.50e-042928215203201
Pubmed

Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons.

CNTNAP3 CNTNAP3B

2.50e-042928231491374
Pubmed

SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome.

RASA1 VAV1

3.05e-043228222974441
Pubmed

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.

ADGRB2 ADGRL2

3.25e-043328225713288
Pubmed

New genetic associations detected in a host response study to hepatitis B vaccine.

JAK1 LIFR FCGBP NCR1 VAV1

4.61e-0482428520237496
Pubmed

The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells.

ZAP70 VAV1

6.33e-044628223793062
Pubmed

HiPLA: High-throughput imaging proximity ligation assay.

RAD52 EHMT2

6.33e-044628230419336
Pubmed

Substrate-trapping techniques in the identification of cellular PTP targets.

JAK1 ZAP70

7.18e-044928215588985
Pubmed

Ggnbp2 Is Essential for Pregnancy Success via Regulation of Mouse Trophoblast Stem Cell Proliferation and Differentiation.

JAK1 LIFR

7.78e-045128226764350
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

ADGRB2 RSBN1 HACL1 KREMEN2 COQ7

7.78e-0492528528986522
InteractionCD5 interactions

RASA1 ZAP70 VAV1

9.51e-0630283int:CD5
InteractionPTK2B interactions

JAK1 RASA1 ZAP70 VAV1

2.12e-05119284int:PTK2B
InteractionABL1 interactions

JAK1 RAD52 RASA1 ZAP70 VAV1

2.60e-05259285int:ABL1
InteractionPLCG1 interactions

JAK1 LIFR RASA1 ZAP70 VAV1

2.85e-05264285int:PLCG1
InteractionBTK interactions

JAK1 IRAK1 PIP5K1B VAV1

4.60e-05145284int:BTK
InteractionCD247 interactions

NCR1 ZAP70 VAV1

6.00e-0555283int:CD247
InteractionPAG1 interactions

RASA1 ZAP70 VAV1

1.08e-0467283int:PAG1
InteractionPTPRC interactions

JAK1 RASA1 ZAP70

1.18e-0469283int:PTPRC
InteractionIL6ST interactions

JAK1 LIFR VAV1

1.46e-0474283int:IL6ST
InteractionPDGFRA interactions

CNTNAP3 JAK1 SEMA3F CNTNAP3B RASA1

1.70e-04385285int:PDGFRA
InteractionNR0B2 interactions

IRAK1 EHMT2 ZAP70

2.05e-0483283int:NR0B2
InteractionSHB interactions

JAK1 ZAP70 VAV1

2.12e-0484283int:SHB
InteractionZAP70 interactions

RASA1 ZAP70 VAV1

2.78e-0492283int:ZAP70
GeneFamilySH2 domain containing

RASA1 ZAP70 VAV1

8.99e-05101163741
GeneFamilyImmunoglobulin like domain containing

SEMA3F NCR1 FCRL6

6.05e-04193163594
GeneFamilyADAM metallopeptidase domain containing|CD molecules

CD274 LIFR NCR1

4.66e-03394163471
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RASA1 VAV1

1.40e-02206162682
ToppCelltumor_Lung-Endothelial_cells-Stalk-like_ECs|tumor_Lung / Location, Cell class and cell subclass

CNTNAP3 SEMA3F LIFR CNTNAP3B ADGRL2

1.25e-0719328521fec35587ffb5c0157e54a821ce3ffd3e24e536
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CNTNAP3 SEMA3F LIFR CNTNAP3B ADGRL2

1.46e-071992853a4deea6e11a0555d27497b7c9983350797aac69
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JAK1 NCR1 ZAP70 FCRL6

2.47e-06153284d8773ee16c7d3e0834b9f64054d42336d6f9833b
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCR1 ZAP70 FCRL6 KREMEN2

2.60e-06155284c58a5fb8d853f12204e961d633e83452eb12a659
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCR1 ZAP70 FCRL6 KREMEN2

2.60e-061552849cb8c42c2e451b2d4dcd7154a4b1bfd21bbb7ea8
ToppCellfacs-Lung-24m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRB2 NCR1 ZAP70 KLHL20

2.74e-0615728434eb1cbdb023d3e23b2e1695c9c327c21ef1c870
ToppCellfacs-Lung-24m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRB2 NCR1 ZAP70 KLHL20

2.74e-06157284fc0c222124f59c94d60335f849554eaa4062f8c7
ToppCellfacs-Lung-24m-Hematologic-Lymphocytic_NK_ILC|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRB2 NCR1 ZAP70 KLHL20

2.74e-0615728440b08ace1d9ea7951886f5fed76ac57e9175436b
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRB2 NCR1 ZAP70 FCRL6

2.88e-06159284d2de9391b00b6c47f5fe28a1bad6da2097107ee0
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRB2 NCR1 ZAP70 FCRL6

2.88e-06159284da6b7f8039adc19839d6c090a0b3d68fb6445a79
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRB2 NCR1 ZAP70 SLC25A34

3.02e-06161284334f540dff3508d451e5e85e8e4e8f3b8d6b74e7
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRB2 NCR1 ZAP70 SLC25A34

3.02e-0616128481d44438e4be4e68a59247e62f02026301a8a0c5
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAK1 NCR1 ZAP70 FCRL6

3.10e-0616228466069146e2666d13c594bd76247893354a697c5d
ToppCelldroplet-Lung-nan-3m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRB2 JAK1 NCR1 ZAP70

3.10e-061622844b490989005bb03d4e7bbea01580f8548eff150f
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRB2 JAK1 NCR1 ZAP70

3.10e-06162284e4a09bf1a51710f6c57e6e01edf8b4619459d96d
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRB2 JAK1 NCR1 ZAP70

3.18e-06163284a0315855c354e830e109d41bd6e3396488aa8de9
ToppCelldroplet-Lung-nan-18m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAK1 NCR1 ZAP70 FCRL6

3.18e-06163284801163c05f8fdacaebd0cb9b4c92741276bfa3e3
ToppCellfacs-GAT-Fat-24m-Lymphocytic-NK_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIP5K1B NCR1 ZAP70 FCRL6

3.18e-06163284e58863a462cc504bced627f004a47890ee2307ce
ToppCelldroplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

JAK1 NCR1 ZAP70 FCRL6

3.25e-06164284c2cd4e4b88cc1b80a9494f59d31339007ff824c1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NCR1 ZAP70 FCRL6 VAV1

3.25e-06164284649e42d9cfdec2f7771d1e938b516e46e7d07078
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NCR1 ZAP70 FCRL6 VAV1

3.25e-06164284ba85f7b21ae34e285d286ada24715885ca6329f7
ToppCelldroplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

JAK1 NCR1 ZAP70 FCRL6

3.25e-06164284d4d08353c7322f97ea07dd583b08661d635fff20
ToppCelldroplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

JAK1 NCR1 ZAP70 FCRL6

3.33e-0616528488745bf7ecb0f7fc93077cea20171d40535dd56b
ToppCelldroplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRB2 JAK1 NCR1 ZAP70

3.50e-06167284cde82e3dacf347226a78873b166608b7851b34d4
ToppCelldroplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRB2 JAK1 NCR1 ZAP70

3.50e-061672846f54a699d9266c5f09ed890a11b403a6c8476fc1
ToppCelldroplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRB2 JAK1 NCR1 ZAP70

3.50e-06167284895844a45721988788d01120eb880603ba3ca139
ToppCellImmune_cells-NK_cells|Immune_cells / Lineage and Cell class

ADGRB2 JAK1 NCR1 ZAP70

3.58e-06168284125d70c37eb49eb4d1f503bb8d536b225254c7cb
ToppCellfacs-Heart-LV-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRB2 NCR1 ZAP70 KREMEN2

3.75e-0617028471e5e27c3c4e6cc8dc9b063bd51c21c049f54416
ToppCellfacs-Heart-LV-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRB2 NCR1 ZAP70 KREMEN2

3.75e-06170284255bbbd00d0e17510c5a8c5faa43ed90d887a9de
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SEMA3F CD274 LIFR ADGRL2

3.84e-061712841ae4b6a25bc9c1065cf5d95998ebcc70aee21ab5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LIFR NCR1 ZAP70 FCRL6

3.93e-0617228486f52f486d67217fc1b8443ab362c975df2974a4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LIFR NCR1 ZAP70 FCRL6

3.93e-06172284fb2df8fea6df5947165f13978f1d1006d15b60fd
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LIFR NCR1 ZAP70 FCRL6

3.93e-06172284e38ebb216e4ddcd008148fcbaf709b4f3c83706a
ToppCellfacs-Skin-nan-24m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRB2 NCR1 ZAP70 SLC25A34

4.12e-061742846863222bec844f40c0c80f5c82a8ff51d1a56d0a
ToppCellfacs-Skin-nan-24m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRB2 NCR1 ZAP70 SLC25A34

4.12e-06174284d570eab215f8287362084e37f35672e20aa0f7a2
ToppCellfacs-Skin-nan-24m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRB2 NCR1 ZAP70 SLC25A34

4.12e-061742845739c1b8d643ad360ef32049832d749c530ca603
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NCR1 ZAP70 FCRL6 VAV1

4.60e-06179284874a9afa91774221c9c1775aa4968ba0aea7b554
ToppCellASK428-Immune-NK_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

HACL1 NCR1 ZAP70 FCRL6

4.71e-06180284857d09446e3e6737e83d0f10bfda2ba282d5ba75
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NCR1 ZAP70 FCRL6 VAV1

4.71e-06180284c62417f205bcbf3b212ae177f63562ec6467c855
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NCR1 ZAP70 FCRL6 VAV1

4.71e-06180284bb2dbf7ed03d5ac765635b7afe738efa822841d0
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTNAP3 SEMA3F LIFR CNTNAP3B

5.24e-06185284a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JAK1 NCR1 ZAP70 FCRL6

5.36e-0618628471e87c4c755ab607689cb050f5a363cb520a0f53
ToppCell10x5'v1-week_12-13-Lymphocytic_NK-T_NK-mature_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

JAK1 NCR1 ZAP70 FCRL6

5.36e-06186284165d02be3b3eaeb8784a2b0b2020928b21a19bc7
ToppCell390C-Lymphocytic-NK_cells-NK_cell_C|390C / Donor, Lineage, Cell class and subclass (all cells)

JAK1 NCR1 ZAP70 FCRL6

5.47e-061872841e8651e6c547384ace5a66b96c6b24a7f390a7ee
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTNAP3 LIFR CNTNAP3B ADGRL2

5.47e-06187284e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-natural_killer_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

JAK1 NCR1 ZAP70 FCRL6

5.59e-06188284a29c43a91ed1364a09d5abab6efa51b8061bce74
ToppCellCOVID-19-lung-Vein_EC|lung / Disease (COVID-19 only), tissue and cell type

SEMA3F LIFR CNTNAP3B ADGRL2

5.59e-06188284d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-CD56_bright_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

JAK1 NCR1 ZAP70 FCRL6

5.59e-061882840a2be6eac6fde669fbc58fd1b2e93e4acf17ddde
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-NK_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JAK1 NCR1 ZAP70 FCRL6

5.71e-061892845a9c3c61998efc40a5d2042e0f568b52103734a9
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

JAK1 NCR1 ZAP70 FCRL6

5.71e-06189284723c57f278919e8251d56b3d19411f9088319450
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK-T_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

JAK1 NCR1 ZAP70 FCRL6

5.71e-06189284960374f5fb278659500a7c948c3068a95dd62eb0
ToppCellASK428-Immune-NK_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

HACL1 NCR1 ZAP70 FCRL6

5.83e-06190284d649f7e17c4227787465dfc02037f791ff85378b
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

CD274 LIFR PIP5K1B ADGRL2

5.83e-061902847f3f419fffe02934b6f27b697f7a6401072491ed
ToppCellCOVID-19-lung-Vein_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SEMA3F LIFR CNTNAP3B ADGRL2

5.83e-061902841caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JAK1 NCR1 ZAP70 FCRL6

5.95e-06191284753deb090b7b78b4ef31604dbe5dbfc4dcf5184a
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JAK1 NCR1 ZAP70 FCRL6

5.95e-06191284355f5bcb220d917163833dead0050fc756c7b260
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JAK1 NCR1 ZAP70 FCRL6

5.95e-06191284337d7d7b89fe370e1fe005b9daad76c5dc3b8444
ToppCell10x5'v1-week_14-16-Lymphocytic_NK-T_NK-mature_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

JAK1 NCR1 ZAP70 FCRL6

6.07e-06192284e48bbcb97c113f323ad4db96bd10d593b9206923
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_NK|lymph-node_spleen / Manually curated celltypes from each tissue

JAK1 NCR1 ZAP70 FCRL6

6.20e-06193284e325cf49e159c6be205ed93adaa09efdd0c122b4
ToppCellTracheal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NCR1 ZAP70 FCRL6 SLC25A34

6.20e-0619328491a1c9b8390cbd881db8c49d8f34feca0d1067d6
ToppCell3'_v3-Lung-Lymphocytic_NK|Lung / Manually curated celltypes from each tissue

JAK1 NCR1 ZAP70 FCRL6

6.20e-06193284a98ee519e0da93ae4a2dcdda1ee8b4138dec131b
ToppCellBac-SEP-Lymphocyte-T_NK-NK|Bac-SEP / Disease, Lineage and Cell Type

JAK1 NCR1 ZAP70 FCRL6

6.20e-061932848aa4ed2b11c6189d86e7de6bc68782fd156a37fb
ToppCellInt-URO-Lymphocyte-T_NK-NK|Int-URO / Disease, Lineage and Cell Type

JAK1 NCR1 ZAP70 FCRL6

6.20e-061932845c7942f630fc69374df34ee3602ad973b6ced17a
ToppCellICU-SEP-Lymphocyte-T_NK-NK|ICU-SEP / Disease, Lineage and Cell Type

JAK1 NCR1 ZAP70 FCRL6

6.20e-06193284f110f86db305e41639087f5b1a2dff103c07adf0
ToppCell10x5'v1-week_14-16-Lymphocytic_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

JAK1 NCR1 ZAP70 FCRL6

6.33e-061942845a859885c0f9b8554b0d203e371c70928ad4418f
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-NK-NK-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JAK1 NCR1 ZAP70 FCRL6

6.33e-061942846b5be379074241973220f7ef02ef3d5d7d8428ef
ToppCell10x5'v1-week_14-16-Lymphocytic_NK-T_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

JAK1 NCR1 ZAP70 FCRL6

6.33e-061942847d35ac70ba966eb1fee4197f7de6d6116326a442
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-NK-NK|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JAK1 NCR1 ZAP70 FCRL6

6.33e-06194284f6a655e1c2be2a326b934db0a5268e4db9112a74
ToppCellILEUM-inflamed-(6)_ILC1|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

JAK1 NCR1 ZAP70 FCRL6

6.33e-06194284dc9ca407ec3ebec1a3dea1213a2beef28c1dc043
ToppCellLeuk-UTI-Lymphocyte-T_NK-NK|Leuk-UTI / Disease, Lineage and Cell Type

JAK1 NCR1 ZAP70 FCRL6

6.33e-0619428436afc4e48d267be3b8aa1e33fad043bcd54c6bc5
ToppCell10x5'v1-week_12-13-Lymphocytic_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

JAK1 NCR1 ZAP70 FCRL6

6.33e-061942845afe7f48d3383f3dac18765f97999c8b6936dc1b
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)|Children_(3_yrs) / Lineage, Cell type, age group and donor

SEMA3F LIFR CNTNAP3B ADGRL2

6.33e-0619428471ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCell10x5'-Liver-Lymphocytic_NK|Liver / Manually curated celltypes from each tissue

JAK1 NCR1 ZAP70 FCRL6

6.33e-061942840b78f4ed84bbaca9f72f005c16c7492bb01d4328
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-NK|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JAK1 NCR1 ZAP70 FCRL6

6.33e-061942844b3f400a5b7b8f999016e2daba50f65f4535b529
ToppCell10x5'v1-week_12-13-Lymphocytic_NK-T_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

JAK1 NCR1 ZAP70 FCRL6

6.33e-06194284ec7e0ca6c9a2f63938e06ee771da09eff14fc3b5
ToppCell3'_v3-Lung-Lymphocytic_NK-NK_CD16|Lung / Manually curated celltypes from each tissue

JAK1 NCR1 ZAP70 FCRL6

6.33e-061942843337042eef91a49f621058785723228cf4dfdad4
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-natural_killer_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

JAK1 NCR1 ZAP70 FCRL6

6.46e-0619528449a4f58aac168fc1838bd5d2b202135cd794c28b
ToppCellIIF-Lymphocyte-T_NK-NK|IIF / Disease, Lineage and Cell Type

JAK1 NCR1 ZAP70 FCRL6

6.46e-06195284464ce05cb52f78aee22d3baa6641b37bd53aae16
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

JAK1 NCR1 ZAP70 FCRL6

6.46e-06195284609732e83ab7fc3ba7dace66f5a17e46557fd6d1
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

JAK1 NCR1 ZAP70 FCRL6

6.46e-06195284acc603dc94ac6518adb0dffb43305b380ec75b52
ToppCellT/NK_cells-CD8+_Naive_T_cell|World / Lineage and Cell class

JAK1 NCR1 ZAP70 FCRL6

6.46e-0619528443f11068beea076e9caeb1572215c3f65c9308e1
ToppCellwk_20-22-Hematologic_Lymphocytic-NK-CD16+_NK|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

JAK1 NCR1 ZAP70 FCRL6

6.46e-061952847533822d2fe551f499b5b2fdec7172f56c79cb44
ToppCell10x5'-Lung-Lymphocytic_NK-NK_CD16|Lung / Manually curated celltypes from each tissue

JAK1 NCR1 ZAP70 FCRL6

6.46e-06195284e91e7f89163c615b706f3297b641b1e4c966f5e6
ToppCellwk_20-22-Hematologic_Lymphocytic-NK|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

JAK1 NCR1 ZAP70 FCRL6

6.46e-06195284a868aadca4a81cfeb773a18b0daad1ea5ece8fa8
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-natural_killer_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

JAK1 NCR1 ZAP70 FCRL6

6.46e-0619528472f42f0be53a2a61f61647118b4883e752d998a5
ToppCellT/NK_cells-CD56dim_NK_cell|World / Lineage and Cell class

JAK1 NCR1 ZAP70 FCRL6

6.46e-061952846124e87cb9061bf8918377fb4a79084079ddfc16
ToppCell10x5'-Lung-Lymphocytic_NK|Lung / Manually curated celltypes from each tissue

JAK1 NCR1 ZAP70 FCRL6

6.46e-06195284a5a10ef9254c266316e5591bec19e159cc3caead
ToppCellnormal-na-Lymphocytic_NK|normal / PBMC cell types (v2) per disease, treatment status, and sex

JAK1 NCR1 ZAP70 FCRL6

6.46e-06195284cebe79c42af5910353ba9ad7d0edb01982f772a3
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_dim|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

JAK1 NCR1 ZAP70 FCRL6

6.59e-061962848e1ed30256a031bb90dac1f167e074c68efbed74
ToppCell10x5'-Liver-Lymphocytic_NK-NK_CD16|Liver / Manually curated celltypes from each tissue

JAK1 NCR1 ZAP70 FCRL6

6.59e-06196284e6d4853ccefbcd45a019cee595811f0474dcc036
ToppCellnormal-na-Lymphocytic_NK-NK_dim-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

JAK1 NCR1 ZAP70 FCRL6

6.59e-0619628461bc0d161e01f36e5bcda4d4f4693afbfe5654bb
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

JAK1 NCR1 ZAP70 FCRL6

6.59e-06196284bd251231288c900b23d3a676ceec6ac07d228917
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

JAK1 NCR1 ZAP70 FCRL6

6.59e-0619628477da6b1bcab45d376eb0368f540e0ed24ce98b42
ToppCellCOVID-19_Severe-Lymphoid_T/NK-NK|COVID-19_Severe / Disease group, lineage and cell class

JAK1 NCR1 ZAP70 FCRL6

6.59e-06196284cc1daf12de5765ba4f7002396352404b41df2012
ToppCelltumor_Lung-T/NK_cells-NK|tumor_Lung / Location, Cell class and cell subclass

JAK1 NCR1 ZAP70 FCRL6

6.59e-06196284006e630f3d8033f45c6b7e9154d77000c7b0cb70
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JAK1 NCR1 ZAP70 FCRL6

6.59e-06196284f424c45be7f34cbef76e1696dea10c1e3a9af2e0
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_dim-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

JAK1 NCR1 ZAP70 FCRL6

6.59e-06196284c25f90c4e5abfe7cfaa85bfe136c438a5179c978
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JAK1 NCR1 ZAP70 FCRL6

6.59e-061962849bb87d20c25df0dc8e48bcb32b57f81a3dc1c0cd
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_dim|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

JAK1 NCR1 ZAP70 FCRL6

6.59e-06196284d451f279f4086fcf727af712f98923551181c76e
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_dim-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

JAK1 NCR1 ZAP70 FCRL6

6.59e-061962845b5cf6f70534661d694f47359b6595b4580876c3
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP3 CNTNAP3B

2.25e-058272DOID:0060308 (implicated_via_orthology)
DiseaseLung Neoplasms

RIOX2 RAD52 CD274 EHMT2

9.49e-05265274C0024121
DiseaseMalignant neoplasm of lung

RIOX2 RAD52 CD274 EHMT2

9.62e-05266274C0242379
Diseasehepatitis C (is_marker_for)

CD274 NCR1

4.71e-0435272DOID:1883 (is_marker_for)
DiseaseHepatitis, Toxic

MST1 IRAK1 HACL1 RASA1

4.73e-04404274C0019193
DiseaseChemically-Induced Liver Toxicity

MST1 IRAK1 HACL1 RASA1

4.73e-04404274C4279912
DiseaseDrug-Induced Liver Disease

MST1 IRAK1 HACL1 RASA1

4.73e-04404274C0860207
DiseaseDrug-Induced Acute Liver Injury

MST1 IRAK1 HACL1 RASA1

4.73e-04404274C3658290
DiseaseChemical and Drug Induced Liver Injury

MST1 IRAK1 HACL1 RASA1

4.73e-04404274C4277682
DiseaseHepatitis, Drug-Induced

MST1 IRAK1 HACL1 RASA1

4.73e-04404274C1262760
Diseasehepatocyte growth factor-like protein measurement

SEMA3F MST1

5.55e-0438272EFO_0008154
DiseaseAdenocarcinoma of lung (disorder)

IRAK1 RASA1 VAV1

8.67e-04206273C0152013
Diseaseparental longevity

ADGRB2 SEMA3F CD274 HACL1

1.00e-03494274EFO_0007796
Diseaseautoimmune thyroid disease, systemic lupus erythematosus, type 1 diabetes mellitus, ankylosing spondylitis, psoriasis, common variable immunodeficiency, celiac disease, ulcerative colitis, Crohn's disease, autoimmune disease, juvenile idiopathic arthritis

RSBN1 ADGRL2

1.87e-0370272EFO_0000384, EFO_0000676, EFO_0000729, EFO_0001060, EFO_0002609, EFO_0003898, EFO_0005140, EFO_0006812, MONDO_0005147, MONDO_0007915, MONDO_0015517
Diseasehypothyroidism

JAK1 CD274 RSBN1

2.17e-03284273EFO_0004705
Diseasemultisite chronic pain

ADGRB2 SEMA3F

3.42e-0395272EFO_0010100
Diseaseestradiol measurement

JAK1 EHMT2

4.55e-03110272EFO_0004697

Protein segments in the cluster

PeptideGeneStartEntry
QRRFRMCQATGTQGY

ADGRB2

496

O60241
GRIGMRIEVYGCAYK

CNTNAP3

166

Q9BZ76
MCYQISRGNSDGYII

ADGRL2

1421

O95490
LEVARYMVQRGGCVY

EHMT2

731

Q96KQ7
LQDAGVYRCMISYGG

CD274

106

Q9NZQ7
RIIAMCGDYYIGGRR

RASA1

231

P20936
YISSRMAGGGQKVCY

RAD52

51

P43351
QICKGMDYLGSRQYV

JAK1

986

P23458
GIKYIGMRNEQAACY

HACL1

51

Q9UJ83
RMAGQYSCIYRVGEL

NCR1

91

O76036
QSRGQYSCSGQVMYI

FCRL6

76

Q6DN72
YGLYCMQSGGINIRI

PIP5K1B

171

O14986
CRMKGYQLAGVEAGY

KREMEN2

156

Q8NCW0
GGFGCVYRAVMRNTV

IRAK1

221

P51617
GCAVYQDMIYAVGGR

KLHL20

501

Q9Y2M5
VRVTVPGNYYQLMCG

FCGBP

3776

Q9Y6R7
YGANRIYAGQMAVLG

COQ7

61

Q99807
GQRATLSGIYRYIMG

FOXS1

36

O43638
YVRTCIMNNGVGYRG

MST1

106

P26927
GRIGMRIEVYGCAYK

CNTNAP3B

166

Q96NU0
LYGCRNQGYQLLRSM

LIFR

701

P42702
NRTYCCGTYRAGPMR

RSBN1

461

Q5VWQ0
GAYNPMCTYVNRGRR

SEMA3F

136

Q13275
GLLYQGLMNGVRFYC

SLC25A34

76

Q6PIV7
GAVNMCYRTLYIGTG

PHF12

806

Q96QT6
CGNFGSVRQGVYRMR

ZAP70

346

P43403
ACQMLLRGTFYQGYR

VAV1

531

P15498
SRGMYYGRDVNVCRC

RIOX2

91

Q8IUF8