Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionGTPase activator activity

ARHGAP42 DOCK2 DOCK3 LRRK2 RGS9 TBC1D8B ECT2 FAM13B TBC1D3B TBC1D8 ARHGAP29 TBC1D3G USP6NL TBC1D3K TBC1D3F

1.45e-0927914215GO:0005096
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

ARHGAP42 DOCK2 DOCK3 GBF1 KALRN LRRK2 RGS9 TBC1D8B ECT2 FAM13B TBC1D3B TBC1D8 FGD4 ARHGAP29 TBC1D3G USP6NL TBC1D3K TBC1D3F

2.18e-0850714218GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

ARHGAP42 DOCK2 DOCK3 GBF1 KALRN LRRK2 RGS9 TBC1D8B ECT2 FAM13B TBC1D3B TBC1D8 FGD4 ARHGAP29 TBC1D3G USP6NL TBC1D3K TBC1D3F

2.18e-0850714218GO:0030695
GeneOntologyMolecularFunctionenzyme activator activity

ARHGAP42 DOCK2 DOCK3 LRRK2 RGS9 TBC1D8B ECT2 FAM13B TBC1D3B TBC1D8 ARHGAP29 TBC1D3G USP6NL TBC1D3K TBC1D3F

6.91e-0565614215GO:0008047
GeneOntologyMolecularFunctionGTPase binding

TNPO1 DOCK2 DOCK3 TNPO2 LRRK2 POU4F1 ECT2 FGD4 DAAM1 USP6NL

2.59e-0436014210GO:0051020
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH17 DNAH8 DYNC1H1

2.66e-04181423GO:0008569
GeneOntologyMolecularFunctionsmall GTPase binding

TNPO1 DOCK2 DOCK3 TNPO2 LRRK2 ECT2 FGD4 DAAM1 USP6NL

4.94e-043211429GO:0031267
GeneOntologyMolecularFunctionferric-chelate reductase (NADPH) activity

STEAP1B STEAP1

4.95e-0451422GO:0052851
GeneOntologyMolecularFunctionferric-chelate reductase activity

STEAP1B STEAP1

4.95e-0451422GO:0000293
GeneOntologyMolecularFunctioncupric reductase (NADH) activity

STEAP1B STEAP1

4.95e-0451422GO:0008823
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

FOXN1 HNF1A POU4F1 POU4F2 POU4F3 POU5F1 ZNF736 POU5F1B TFCP2 ZNF780A ZNF726 MYBL2

6.71e-0456014212GO:0001228
GeneOntologyMolecularFunctioncarbon-carbon lyase activity

DDC GGCX GADL1 TYW1

6.76e-04561424GO:0016830
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

FOXN1 HNF1A POU4F1 POU4F2 POU4F3 POU5F1 ZNF736 POU5F1B TFCP2 ZNF780A ZNF726 MYBL2

7.37e-0456614212GO:0001216
GeneOntologyMolecularFunction3'-5' RNA helicase activity

YTHDC2 SUPV3L1

7.39e-0461422GO:0034458
GeneOntologyMolecularFunctionhelicase activity

DHX37 RECQL YTHDC2 SUPV3L1 NAV2 CHD6

9.43e-041581426GO:0004386
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH17 DNAH8 DYNC1H1

1.01e-03281423GO:0051959
GeneOntologyMolecularFunctionPOU domain binding

POU5F1 POU5F1B

1.03e-0371422GO:0070974
GeneOntologyMolecularFunctionoxidoreductase activity, acting on metal ions, NAD or NADP as acceptor

STEAP1B STEAP1

1.03e-0371422GO:0016723
GeneOntologyMolecularFunctionalpha-glucosidase activity

AGL MGAM2

1.03e-0371422GO:0090599
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA13 DHX37 RECQL YTHDC2 KATNA1 SUPV3L1 NAV2 CHD6 DNAH8 DYNC1H1

1.24e-0344114210GO:0016887
GeneOntologyMolecularFunctionATP-dependent activity

ATP6V1B1 ABCA13 DHX37 RECQL YTHDC2 KATNA1 SUPV3L1 DNAH17 NAV2 CHD6 DNAH8 DYNC1H1

1.48e-0361414212GO:0140657
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

POU4F1 POU4F2 POU5F1 ZNF736 POU5F1B ZNF512B PAX4 ZNF726

2.09e-033201428GO:0001227
GeneOntologyMolecularFunctioncarboxy-lyase activity

DDC GGCX GADL1

2.12e-03361423GO:0016831
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH17 DNAH8 DYNC1H1

2.29e-03371423GO:0045505
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

POU4F1 POU4F2 POU5F1 ZNF736 POU5F1B ZNF512B PAX4 ZNF726

2.35e-033261428GO:0001217
GeneOntologyBiologicalProcessactivation of GTPase activity

ARHGAP42 TBC1D8B ECT2 TBC1D3B TBC1D8 ARHGAP29 TBC1D3G USP6NL TBC1D3K TBC1D3F

3.61e-0910914010GO:0090630
GeneOntologyBiologicalProcessregulation of GTPase activity

ARHGAP42 KALRN LRRK2 RGS9 TBC1D8B ECT2 TBC1D3B TBC1D8 FGD4 ARHGAP29 TBC1D3G USP6NL TBC1D3K TBC1D3F

6.99e-0833514014GO:0043087
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

ARHGAP42 KALRN RGS9 TBC1D8B ECT2 TBC1D3B TBC1D8 ARHGAP29 TBC1D3G USP6NL TBC1D3K TBC1D3F

1.10e-0724414012GO:0043547
GeneOntologyBiologicalProcesscilium assembly

IFT140 SPAG1 GBF1 USP9X CEP290 CILK1 RO60 ALPK1 TBC1D8 DNAH17 PARVA DNAH8 USP6NL

1.08e-0544414013GO:0060271
GeneOntologyBiologicalProcesscell projection assembly

IFT140 SPAG1 GBF1 USP9X CEP290 CILK1 RO60 ALPK1 PARVG TBC1D8 FGD4 DNAH17 PARVA DNAH8 PLS1 USP6NL

1.72e-0568514016GO:0030031
GeneOntologyBiologicalProcesscilium organization

IFT140 SPAG1 GBF1 USP9X CEP290 CILK1 RO60 ALPK1 TBC1D8 DNAH17 PARVA DNAH8 USP6NL

2.24e-0547614013GO:0044782
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

IFT140 SPAG1 GBF1 USP9X CEP290 CILK1 RO60 ALPK1 TBC1D8 FGD4 DNAH17 PARVA DNAH8 PLS1 USP6NL

5.18e-0567014015GO:0120031
GeneOntologyBiologicalProcessorganelle assembly

IFT140 SPAG1 GBF1 DHX37 USP9X CEP290 LRRK2 CILK1 FHOD3 RO60 ALPK1 TBC1D8 DNAH17 PARVA ATM DNAH8 PLS1 USP6NL DYNC1H1 MYBL2

8.63e-05113814020GO:0070925
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

ARHGAP42 DOCK2 DOCK3 GBF1 KALRN MYOC ECT2 FAM13B FGD4 ARHGAP29

9.45e-0533314010GO:0051056
GeneOntologyBiologicalProcesstrophectodermal cell fate commitment

POU5F1 POU5F1B

1.37e-0431402GO:0001830
GeneOntologyBiologicalProcesspositive regulation of hydrolase activity

ARHGAP42 KALRN RGS9 TBC1D8B ECT2 TBC1D3B TBC1D8 ARHGAP29 TBC1D3G USP6NL TBC1D3K TBC1D3F

1.56e-0449914012GO:0051345
Domain-

HNF1A POU6F2 POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B

9.90e-102714271.10.260.40
DomainPOU

POU6F2 POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B

1.31e-09161426SM00352
DomainPOU_dom

POU6F2 POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B

1.31e-09161426IPR000327
DomainPou

POU6F2 POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B

1.31e-09161426PF00157
DomainPOU_1

POU6F2 POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B

1.31e-09161426PS00035
DomainPOU_2

POU6F2 POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B

1.31e-09161426PS00465
DomainPOU_3

POU6F2 POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B

1.31e-09161426PS51179
DomainLambda_DNA-bd_dom

HNF1A POU6F2 POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B

1.72e-09291427IPR010982
DomainPOU

POU6F2 POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B

2.01e-09171426IPR013847
DomainTBC

TBC1D8B TBC1D3B TBC1D8 TBC1D3G USP6NL TBC1D3K TBC1D3F

8.33e-08491427SM00164
DomainRabGAP-TBC

TBC1D8B TBC1D3B TBC1D8 TBC1D3G USP6NL TBC1D3K TBC1D3F

1.46e-07531427PF00566
DomainRab-GTPase-TBC_dom

TBC1D8B TBC1D3B TBC1D8 TBC1D3G USP6NL TBC1D3K TBC1D3F

1.89e-07551427IPR000195
DomainTBC_RABGAP

TBC1D8B TBC1D3B TBC1D8 TBC1D3G USP6NL TBC1D3K TBC1D3F

1.89e-07551427PS50086
DomainARM-type_fold

TNPO1 DOCK2 DOCK3 USP34 SMG1 GBF1 USP9X TNPO2 LRRK2 FHOD3 RRP12 ATM DAAM1

1.96e-0633914213IPR016024
DomainATM/Tel1

SMG1 ATM

5.74e-0521422IPR015519
Domain-

HNF1A POU6F2 POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B SMARCC1 PAX4 MYBL2

6.23e-05283142101.10.10.60
DomainParvin

PARVG PARVA

1.71e-0431422IPR028433
DomainPOU_dom_5

POU5F1 POU5F1B

1.71e-0431422IPR015585
DomainARM-like

TNPO1 DOCK2 SMG1 USP9X TNPO2 LRRK2 FHOD3 RRP12 DAAM1

2.26e-042701429IPR011989
DomainHomeodomain-like

HNF1A POU6F2 POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B SMARCC1 PAX4 MYBL2

2.30e-0433214210IPR009057
DomainTRPM_tetra

TRPM7 TRPM3

3.41e-0441422PF16519
DomainTRPM_tetra

TRPM7 TRPM3

3.41e-0441422IPR032415
DomainHomeobox

HNF1A POU6F2 POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B PAX4

4.28e-042341428PF00046
DomainHOMEOBOX_1

HNF1A POU6F2 POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B PAX4

4.53e-042361428PS00027
DomainHOX

HNF1A POU6F2 POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B PAX4

4.66e-042371428SM00389
DomainHOMEOBOX_2

HNF1A POU6F2 POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B PAX4

4.93e-042391428PS50071
DomainHomeobox_dom

HNF1A POU6F2 POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B PAX4

4.93e-042391428IPR001356
DomainDOCK_N

DOCK2 DOCK3

5.65e-0451422PF16172
DomainDOCK_N

DOCK2 DOCK3

5.65e-0451422IPR032376
DomainPyridoxal-P_BS

DDC GADL1

5.65e-0451422IPR021115
DomainFATC

SMG1 ATM

5.65e-0451422PF02260
DomainAlpha_kinase

TRPM7 ALPK1

8.44e-0461422PF02816
DomainMHCK_EF2_kinase

TRPM7 ALPK1

8.44e-0461422IPR004166
DomainFAT

SMG1 ATM

8.44e-0461422PS51189
DomainFATC

SMG1 ATM

8.44e-0461422PS51190
DomainALPHA_KINASE

TRPM7 ALPK1

8.44e-0461422PS51158
DomainAlpha_kinase

TRPM7 ALPK1

8.44e-0461422SM00811
DomainFATC_dom

SMG1 ATM

8.44e-0461422IPR003152
DomainPIK_FAT

SMG1 ATM

8.44e-0461422IPR014009
DomainFATC

SMG1 ATM

8.44e-0461422SM01343
DomainKinase-like_dom

SMG1 KALRN TRPM7 ADCK1 LRRK2 CILK1 ALPK1 GUCY2D SMARCC1 ATM MERTK WNK4

9.00e-0454214212IPR011009
DomainHelicase_C

DHX37 RECQL YTHDC2 SUPV3L1 CHD6

1.35e-031071425PF00271
DomainHELICc

DHX37 RECQL YTHDC2 SUPV3L1 CHD6

1.35e-031071425SM00490
Domain-

FOXN1 RECQL RGS9 SSB CUL5 SMARCC1 PAX4

1.41e-0321814271.10.10.10
DomainHelicase_C

DHX37 RECQL YTHDC2 SUPV3L1 CHD6

1.41e-031081425IPR001650
DomainHELICASE_CTER

DHX37 RECQL YTHDC2 SUPV3L1 CHD6

1.47e-031091425PS51194
DomainHELICASE_ATP_BIND_1

DHX37 RECQL YTHDC2 SUPV3L1 CHD6

1.47e-031091425PS51192
DomainCH

PARVG PARVA NAV2 PLS1

1.51e-03651424SM00033
DomainDAD_dom

FHOD3 DAAM1

1.56e-0381422IPR014767
DomainDHC_N1

DNAH8 DYNC1H1

1.56e-0381422PF08385
DomainDAD

FHOD3 DAAM1

1.56e-0381422PS51231
DomainPyrdxlP-dep_de-COase

DDC GADL1

1.56e-0381422IPR002129
DomainPyridoxal_deC

DDC GADL1

1.56e-0381422PF00282
DomainDDC_GAD_HDC_YDC

DDC GADL1

1.56e-0381422PS00392
DomainDynein_heavy_dom-1

DNAH8 DYNC1H1

1.56e-0381422IPR013594
Domain-

ATP6V1B1 ABCA13 DHX37 LRRK2 RECQL YTHDC2 KATNA1 NWD2 TRANK1 SUPV3L1 NAV2 CHD6 DNAH8 DYNC1H1

1.66e-03746142143.40.50.300
DomainCH

PARVG PARVA NAV2 PLS1

1.99e-03701424PF00307
Domain-

PARVG PARVA NAV2 PLS1

2.10e-037114241.10.418.10
DomainCH

PARVG PARVA NAV2 PLS1

2.32e-03731424PS50021
DomainWHTH_DNA-bd_dom

FOXN1 RECQL RGS9 SSB CUL5 SMARCC1 PAX4

2.54e-032421427IPR011991
DomainCH-domain

PARVG PARVA NAV2 PLS1

2.56e-03751424IPR001715
DomainDEAH_ATP_HELICASE

DHX37 YTHDC2 CHD6

2.99e-03381423PS00690
DomainHomeobox_CS

POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B PAX4

3.01e-031861426IPR017970
DomainGBD/FH3_dom

FHOD3 DAAM1

3.02e-03111422IPR014768
DomainGBD_FH3

FHOD3 DAAM1

3.02e-03111422PS51232
DomainDHR-1_domain

DOCK2 DOCK3

3.02e-03111422IPR027007
DomainDHR_2

DOCK2 DOCK3

3.02e-03111422PS51651
DomainDHR_1

DOCK2 DOCK3

3.02e-03111422PS51650
DomainDHR-2

DOCK2 DOCK3

3.02e-03111422PF06920
DomainDOCK

DOCK2 DOCK3

3.02e-03111422IPR026791
DomainPNMA

ZCCHC18 ZCCHC12

3.02e-03111422IPR026523
DomainDOCK_C

DOCK2 DOCK3

3.02e-03111422IPR010703
DomainDOCK-C2

DOCK2 DOCK3

3.02e-03111422PF14429
DomainDHR-2

DOCK2 DOCK3

3.02e-03111422IPR027357
DomainPNMA

ZCCHC18 ZCCHC12

3.02e-03111422PF14893
DomainFerric_reduct

STEAP1B STEAP1

3.60e-03121422PF01794
DomainFe3_Rdtase_TM_dom

STEAP1B STEAP1

3.60e-03121422IPR013130
DomainAAA

ABCA13 KATNA1 NAV2 DNAH8 DYNC1H1

4.90e-031441425SM00382
DomainAAA+_ATPase

ABCA13 KATNA1 NAV2 DNAH8 DYNC1H1

4.90e-031441425IPR003593
DomainDynein_heavy_chain_D4_dom

DNAH8 DYNC1H1

4.92e-03141422IPR024317
DomainDynein_HC_stalk

DNAH8 DYNC1H1

4.92e-03141422IPR024743
DomainDynein_heavy_dom-2

DNAH8 DYNC1H1

4.92e-03141422IPR013602
DomainDHC_N2

DNAH8 DYNC1H1

4.92e-03141422PF08393
DomainIMPORTIN_B_NT

TNPO1 TNPO2

4.92e-03141422PS50166
DomainATPase_dyneun-rel_AAA

DNAH8 DYNC1H1

4.92e-03141422IPR011704
DomainMT

DNAH8 DYNC1H1

4.92e-03141422PF12777
DomainAAA_8

DNAH8 DYNC1H1

4.92e-03141422PF12780
DomainAAA_5

DNAH8 DYNC1H1

4.92e-03141422PF07728
DomainP-loop_NTPase

ATP6V1B1 ABCA13 DHX37 LRRK2 RECQL YTHDC2 KATNA1 NWD2 TRANK1 SUPV3L1 NAV2 CHD6 DNAH8 DYNC1H1

5.25e-0384814214IPR027417
DomainWW

TCERG1L WWC2 PCIF1

5.46e-03471423PF00397
DomainDHC_fam

DNAH8 DYNC1H1

5.65e-03151422IPR026983
DomainFH2

FHOD3 DAAM1

5.65e-03151422PS51444
DomainDynein_heavy

DNAH8 DYNC1H1

5.65e-03151422PF03028
DomainPI3/4_kinase_CS

SMG1 ATM

5.65e-03151422IPR018936
DomainFH2_Formin

FHOD3 DAAM1

5.65e-03151422IPR015425
DomainFH2

FHOD3 DAAM1

5.65e-03151422PF02181
DomainIBN_N

TNPO1 TNPO2

5.65e-03151422PF03810
DomainDynein_heavy_dom

DNAH8 DYNC1H1

5.65e-03151422IPR004273
DomainFH2

FHOD3 DAAM1

5.65e-03151422SM00498
DomainWW

TCERG1L WWC2 PCIF1

5.80e-03481423SM00456
PathwayREACTOME_RHO_GTPASE_CYCLE

VAPB ARHGAP42 DOCK2 DOCK3 KALRN USP9X NDUFA5 ECT2 FAM13B ZNF512B FGD4 ARHGAP29 DAAM1

5.24e-0545011113M27078
PathwayREACTOME_RHOA_GTPASE_CYCLE

VAPB ARHGAP42 DOCK2 KALRN ECT2 ARHGAP29 DAAM1

1.29e-041421117MM15576
PathwayREACTOME_RHO_GTPASE_CYCLE

VAPB ARHGAP42 DOCK2 KALRN USP9X NDUFA5 ECT2 FAM13B ZNF512B FGD4 ARHGAP29 DAAM1

1.74e-0443911112MM15595
PathwayREACTOME_RHOA_GTPASE_CYCLE

VAPB ARHGAP42 DOCK2 KALRN ECT2 ARHGAP29 DAAM1

1.74e-041491117M41805
Pubmed

Requirement for Brn-3b in early differentiation of postmitotic retinal ganglion cell precursors.

POU6F2 POU4F1 POU4F2 POU4F3

4.08e-09614349630743
Pubmed

Role of the Brn-3 family of POU-domain genes in the development of the auditory/vestibular, somatosensory, and visual systems.

POU4F1 POU4F2 POU4F3

6.81e-08314339598366
Pubmed

Differential expression of Brn3 transcription factors in intrinsically photosensitive retinal ganglion cells in mouse.

POU4F1 POU4F2 POU4F3

6.81e-083143321935940
Pubmed

Systematic identification of intergenic long-noncoding RNAs in mouse retinas using full-length isoform sequencing.

POU4F1 POU4F2 POU4F3

6.81e-083143331286854
Pubmed

Chromosomal localization and sequences of the murine Brn-3 family of developmental control genes.

POU4F1 POU4F2 POU4F3

6.81e-08314338162704
Pubmed

Mouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3a.

POU4F1 POU4F2 POU4F3

6.81e-08314338290353
Pubmed

The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons.

POU4F1 POU4F2 POU4F3

6.81e-08314337623109
Pubmed

The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain.

POU4F1 POU4F2 POU4F3

6.81e-08314337935408
Pubmed

TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.

TBC1D3B TBC1D3G TBC1D3K TBC1D3F

8.84e-0811143416863688
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

TNPO1 USP34 EPPK1 RPS2 DHX37 USP9X NUP88 RECQL PFAS YTHDC2 SSB RRP12 SMARCC1 ATM DYNC1H1

9.04e-086531431522586326
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

VAPB TNPO1 GBF1 RPS2 DHX37 USP9X NUP88 RECQL PFAS YTHDC2 RO60 SSB TFCP2 YARS1 SUPV3L1 RRP12 FEN1 SMARCC1 ATM FAR1 DYNC1H1 MGAM2

9.38e-0814251432230948266
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

TNPO1 DOCK2 EPPK1 MAGEE2 YTHDC2 RNF17 SEC31B ECT2 PRPF3 SUPV3L1 FEN1 PARVA ATM DYNC1H1

1.42e-075821431420467437
Pubmed

Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development.

POU4F1 POU4F2 POU4F3

2.71e-07414339256502
Pubmed

Identification of retinal ganglion cell types and brain nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele.

POU4F1 POU4F2 POU4F3

2.71e-074143333135183
Pubmed

Morphologies of mouse retinal ganglion cells expressing transcription factors Brn3a, Brn3b, and Brn3c: analysis of wild type and mutant cells using genetically-directed sparse labeling.

POU4F1 POU4F2 POU4F3

2.71e-074143320826176
Pubmed

Fine-Tuning Mybl2 Is Required for Proper Mesenchymal-to-Epithelial Transition during Somatic Reprogramming.

POU5F1 POU5F1B MYBL2

2.71e-074143330089261
Pubmed

The mouse T complex gene Tsga2, encoding polypeptides located in the sperm tail and anterior acrosome, maps to a locus associated with sperm motility and sperm-egg interaction abnormalities.

POU5F1 POU5F1B DNAH8

2.71e-074143316354795
Pubmed

Genetic interactions between Brn3 transcription factors in retinal ganglion cell type specification.

POU4F1 POU4F2 POU4F3

2.71e-074143324116103
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DOCK3 USP34 ZCCHC12 KALRN TRPM7 USP9X TNPO2 CEP290 ANKRD49 SEC31B YARS1 ZNF512B ACAD8 SUPV3L1 ZNF92 CHD6 ATM MERTK DYNC1H1 BRWD1

3.38e-0712851432035914814
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

VAPB RPS2 USP9X RECQL PFAS SSB YARS1 CUL5 SUPV3L1 AGL FEN1 FAR1 DYNC1H1

3.55e-075341431335032548
Pubmed

POU family transcription factors in the nervous system.

POU4F1 POU5F1 POU5F1B

6.77e-075143310199551
Pubmed

A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells.

POU4F2 POU5F1 POU5F1B

6.77e-07514331967980
Pubmed

Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development.

POU4F1 POU4F2 POU4F3

6.77e-07514338637595
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK2 DOCK3 GBF1 CEP290 ZFP28 CILK1 PFAS ALPK1 MYOF TRPM3 DNAH17 TMEM132A

1.02e-064931431215368895
Pubmed

Distinct effects of importin α2 and α4 on Oct3/4 localization and expression in mouse embryonic stem cells.

TNPO2 POU5F1 POU5F1B

1.35e-066143321840941
Pubmed

B-MYB is essential for normal cell cycle progression and chromosomal stability of embryonic stem cells.

POU5F1 POU5F1B MYBL2

1.35e-066143318575582
Pubmed

POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells.

POU4F1 POU4F2 POU4F3

1.35e-06614338632990
Pubmed

Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth.

POU4F1 POU4F2 POU4F3

1.35e-066143311807038
Pubmed

The Wilms' tumor gene Wt1 is required for normal development of the retina.

POU4F1 POU4F2 POU4F3

1.35e-066143311889045
Pubmed

Gfi1-Cre knock-in mouse line: A tool for inner ear hair cell-specific gene deletion.

POU4F1 POU4F2 POU4F3

1.35e-066143320533399
Pubmed

Combinatorial expression of Brn3 transcription factors in somatosensory neurons: genetic and morphologic analysis.

POU4F1 POU4F2 POU4F3

1.35e-066143322262898
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

TNPO1 USP34 GBF1 RPS2 USP9X NUP88 RECQL PFAS AASDHPPT RO60 SSB PLD3 YARS1 CUL5 AGL FEN1 PARVA PLA2G4A PLS1 DYNC1H1

2.29e-0614551432022863883
Pubmed

Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2.

POU4F1 POU5F1 POU5F1B

2.35e-067143320081188
Pubmed

Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells.

POU4F1 POU4F2 POU4F3

2.35e-06714339735355
Pubmed

TIF1beta regulates the pluripotency of embryonic stem cells in a phosphorylation-dependent manner.

POU5F1 POU5F1B SMARCC1

2.35e-067143320508149
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

FOXN1 GBF1 DCUN1D5 RECQL ECT2 TFCP2 YARS1 PHF21A LACTB AGL FEN1 SMARCC1 PLA2G4A DYNC1H1 MYBL2

2.73e-068571431525609649
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

EPPK1 DHX37 SLC6A17 NUP88 PFAS AASDHPPT RNF17 YARS1 ZNF512B MYOF PRPF3 SMARCC1 CHD6 DYNC1H1

3.04e-067541431435906200
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

VAPB TNPO1 SPAG1 EPPK1 GBF1 PDPR RPS2 USP9X RECQL PFAS SSB NDUFA5 PARVG MYOF SUPV3L1 AGL RRP12 FEN1 SMARCC1

3.58e-0613671431932687490
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

TNPO1 USP34 GBE1 RECQL SSB PRPF3 FEN1 SMARCC1

3.86e-06220143835785414
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

DOCK3 CEP290 PFAS TRANK1 RIMBP2 DYNC1H1

4.74e-0610414369205841
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

HNF1A EPPK1 GBF1 DHX37 USP9X TNPO2 PFAS RO60 EXT2 SSB YARS1 CUL5 PRPF3 RRP12 PARVA SMARCC1 FAR1 DYNC1H1

5.88e-0612841431817353931
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

VAPB ARHGAP42 DOCK2 DOCK3 EPPK1 SSB NDUFA5 ECT2 FAM13B PRPF3 FGD4 FEN1 ARHGAP29 SMARCC1 CDCA5

6.07e-069161431532203420
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

EPPK1 PDPR RPS2 DHX37 NUP88 RECQL PFAS YTHDC2 AGL FEN1 SMARCC1 DNAH8 DYNC1H1

7.39e-067041431329955894
Pubmed

RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors.

POU4F1 POU4F2 POU4F3

8.00e-0610143323805044
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

VAPB TNPO1 USP9X NUP88 RDH14 RO60 EXT2 NDUFA5 PLD3 RRP12 FEN1 SARAF FAR1 QSOX2 DYNC1H1

8.46e-069421431531073040
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

ZCCHC18 USP34 SMG1 GBF1 SSB WWC2 TRPM3 ARHGAP29 CHD6 DNAH8

1.02e-054201431028065597
Pubmed

Use of Chuk as an internal standard suitable for quantitative RT-PCR in mouse preimplantation embryos.

POU5F1 POU5F1B PARVA

1.10e-0511143316984773
Pubmed

Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons.

POU4F1 POU4F2 POU4F3

1.10e-051114338955272
Pubmed

Survival Motor Neuron Enhances Pluripotent Gene Expression and Facilitates Cell Reprogramming.

POU4F1 POU5F1 POU5F1B

1.10e-0511143335848514
Pubmed

Endogenous retroviruses shape pluripotency specification in mouse embryos.

POU5F1 POU5F1B SMARCC1

1.10e-0511143338266080
Pubmed

Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling.

POU4F1 POU4F2 POU4F3

1.10e-051114338876243
Pubmed

The Ciliary Margin Zone of the Mammalian Retina Generates Retinal Ganglion Cells.

POU4F1 POU4F2 POU4F3

1.10e-0511143328009286
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

VAPB TNPO1 PDPR TRPM7 EMC9 PFAS EXT2 NDUFA5 PLD3 TFCP2 LACTB ZNF512B TBC1D8 RRP12 TYW1 ATM DAAM1 FAR1 USP6NL

1.18e-0514871431933957083
Pubmed

Essential and overlapping functions for mammalian Argonautes in microRNA silencing.

HNF1A POU5F1 POU5F1B

1.46e-0512143319174539
Pubmed

Ascl1 expression defines a subpopulation of lineage-restricted progenitors in the mammalian retina.

POU4F1 POU4F2 POU4F3

1.46e-0512143321771810
Pubmed

Identification of mouse blastocyst genes that are downregulated by double-stranded RNA-mediated knockdown of Oct-4 expression.

POU5F1 POU5F1B

1.68e-052143215685634
Pubmed

Identification of proteins that interact with murine cytomegalovirus early protein M112-113 in brain.

ZCCHC18 ZCCHC12

1.68e-052143222340173
Pubmed

Nuclear and chromatin reorganization in the MHC-Oct3/4 locus at developmental phases of embryonic stem cell differentiation.

POU5F1 POU5F1B

1.68e-052143216950240
Pubmed

Maternal Oct-4 is a potential key regulator of the developmental competence of mouse oocytes.

POU5F1 POU5F1B

1.68e-052143218837968
Pubmed

Cruciform Formable Sequences within Pou5f1 Enhancer Are Indispensable for Mouse ES Cell Integrity.

POU5F1 POU5F1B

1.68e-052143233810223
Pubmed

Phosphorylation of Threonine343 Is Crucial for OCT4 Interaction with SOX2 in the Maintenance of Mouse Embryonic Stem Cell Pluripotency.

POU5F1 POU5F1B

1.68e-052143228988986
Pubmed

Abnormal DNA methylation of the Oct-4 enhancer region in cloned mouse embryos.

POU5F1 POU5F1B

1.68e-052143218932201
Pubmed

Short isoform of POU factor Brn-3b can form a heterodimer with Brn-3a that is inactive for octamer motif binding.

POU4F1 POU4F2

1.68e-05214328537352
Pubmed

A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo.

POU5F1 POU5F1B

1.68e-05214321972777
Pubmed

Mouse Oct-3 maps between the tcl12 embryonic lethal gene and the Qa gene in the H-2 complex.

POU5F1 POU5F1B

1.68e-05214321680810
Pubmed

Brn3 transcription factors control terminal osteoclastogenesis.

POU4F1 POU4F2

1.68e-052143217668438
Pubmed

SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress.

SMG1 ATM

1.68e-052143231565865
Pubmed

Heterogeneous DNA methylation status of the regulatory element of the mouse Oct4 gene in adult somatic cell population.

POU5F1 POU5F1B

1.68e-052143215996113
Pubmed

Oct4 transcription factor in conjunction with valproic acid accelerates myelin repair in demyelinated optic chiasm in mice.

POU5F1 POU5F1B

1.68e-052143226804242
Pubmed

Conserved, developmentally regulated mechanism couples chromosomal looping and heterochromatin barrier activity at the homeobox gene A locus.

POU5F1 POU5F1B

1.68e-052143221502535
Pubmed

Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of Oct-3/4 in embryonic stem cells.

POU5F1 POU5F1B

1.68e-052143211839818
Pubmed

A novel Oct4/Pou5f1-like non-coding RNA controls neural maturation and mediates developmental effects of ethanol.

POU5F1 POU5F1B

1.68e-052143233221301
Pubmed

Developmental fate of embryonic germ cells (EGCs), in vivo and in vitro.

POU5F1 POU5F1B

1.68e-052143212641567
Pubmed

A nontranscriptional role for Oct4 in the regulation of mitotic entry.

POU5F1 POU5F1B

1.68e-052143225324523
Pubmed

Novel variants of Oct-3/4 gene expressed in mouse somatic cells.

POU5F1 POU5F1B

1.68e-052143218765667
Pubmed

Oct4 dependence of chromatin structure within the extended Nanog locus in ES cells.

POU5F1 POU5F1B

1.68e-052143218283123
Pubmed

Mechanisms of OCT4 on 3,5,3'-Tri-iodothyronine and FSH-induced Granulosa Cell Development in Female Mice.

POU5F1 POU5F1B

1.68e-052143234463738
Pubmed

Differential expression of Oct3/4 in human breast cancer and normal tissues.

POU5F1 POU5F1B

1.68e-052143229620155
Pubmed

Glutamine Metabolism Regulates the Pluripotency Transcription Factor OCT4.

POU5F1 POU5F1B

1.68e-052143227346346
Pubmed

Critical POU domain residues confer Oct4 uniqueness in somatic cell reprogramming.

POU5F1 POU5F1B

1.68e-052143226877091
Pubmed

The embryonic Octamer factor 3/4 displays distinct DNA binding specificity from those of other Octamer factors.

POU5F1 POU5F1B

1.68e-052143212615074
Pubmed

hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress.

SMG1 ATM

1.68e-052143218332866
Pubmed

Effect of ectopic expression of homeoprotein EGAM1C on the cell morphology, growth, and differentiation in a mouse embryonic stem cell line, MG1.19 cells.

POU5F1 POU5F1B

1.68e-052143222367590
Pubmed

Inhibition of neuronal process outgrowth and neuronal specific gene activation by the Brn-3b transcription factor.

POU4F1 POU4F2

1.68e-05214328995448
Pubmed

Targeted disruption of organic cation transporter 3 (Oct3) ameliorates ischemic brain damage through modulating histamine and regulatory T cells.

POU5F1 POU5F1B

1.68e-052143222739622
Pubmed

Oct-4: more than just a POUerful marker of the mammalian germline?

POU5F1 POU5F1B

1.68e-05214329524569
Pubmed

Transient pairing of homologous Oct4 alleles accompanies the onset of embryonic stem cell differentiation.

POU5F1 POU5F1B

1.68e-052143225748933
Pubmed

Expression pattern of Oct-4 in preimplantation embryos of different species.

POU5F1 POU5F1B

1.68e-052143211090438
Pubmed

A saturating mutagenesis CRISPR-Cas9-mediated functional genomic screen identifies cis- and trans-regulatory elements of Oct4 in murine ESCs.

POU5F1 POU5F1B

1.68e-052143232994224
Pubmed

Differential expression of four members of the POU family of proteins in activated and phorbol 12-myristate 13-acetate-treated Jurkat T cells.

POU4F1 POU4F2

1.68e-05214328234287
Pubmed

Networks of Transcription Factors for Oct4 Expression in Mice.

POU5F1 POU5F1B

1.68e-052143228731785
Pubmed

Oct-4 controls cell-cycle progression of embryonic stem cells.

POU5F1 POU5F1B

1.68e-052143219968627
Pubmed

A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages.

POU5F1 POU5F1B

1.68e-052143223629142
Pubmed

Involvement of Oct3/4 in the enhancement of neuronal differentiation of ES cells in neurogenesis-inducing cultures.

POU5F1 POU5F1B

1.68e-052143212702663
Pubmed

Inhibition of retinal guanylyl cyclase by the RGS9-1 N-terminus.

RGS9 GUCY2D

1.68e-052143211485301
Pubmed

Serine 249 phosphorylation by ATM protein kinase regulates hepatocyte nuclear factor-1α transactivation.

HNF1A ATM

1.68e-052143224821553
Pubmed

Changes in the Expression of Pluripotency Factor Oct-4 and Intensity of Apoptosis in the Uterus during Spontaneous and Immune-Dependent Abortions in Mice.

POU5F1 POU5F1B

1.68e-052143235501657
Pubmed

Hierarchical Oct4 Binding in Concert with Primed Epigenetic Rearrangements during Somatic Cell Reprogramming.

POU5F1 POU5F1B

1.68e-052143226832419
Pubmed

Oct4 was a novel target of Wnt signaling pathway.

POU5F1 POU5F1B

1.68e-052143222120493
Pubmed

Analysis of a transgenic Oct4 enhancer reveals high fidelity long-range chromosomal interactions.

POU5F1 POU5F1B

1.68e-052143226435056
CytobandEnsembl 112 genes in cytogenetic band chr11q22

ARHGAP42 DCUN1D5 AASDHPPT CUL5 ATM

2.33e-051071445chr11q22
GeneFamilyPOU class homeoboxes and pseudogenes

POU6F2 POU4F1 POU4F2 POU4F3 POU5F1 POU5F1B

1.68e-0923956523
GeneFamilyParvins

PARVG PARVA

8.17e-053952673
GeneFamilyProteases, serine|STEAP family

STEAP1B STEAP1

2.70e-0459521324
GeneFamilyParaneoplastic Ma antigens

ZCCHC18 ZCCHC12

1.46e-0311952671
GeneFamilyWD repeat domain containing|GRAM domain containing|BEACH domain containing

TBC1D8B TBC1D8

2.05e-03139521146
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP42 FAM13B ARHGAP29

2.30e-0350953721
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

SMARCC1 CHD6 MYBL2

2.72e-0353953532
GeneFamilyDyneins, axonemal

DNAH17 DNAH8

3.53e-0317952536
GeneFamilyArmadillo repeat containing|Importins

TNPO1 TNPO2

3.96e-0318952596
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

KALRN ECT2 FGD4

5.06e-0366953722
GeneFamilyShort chain dehydrogenase/reductase superfamily

RDH14 BDH1 FAR1

7.49e-0376953743
GeneFamilyZinc fingers CCHC-type|RNA binding motif containing

ZCCHC18 ZCCHC12

7.58e-032595274
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

DOCK3 SMG1 PDPR USP9X GNG13 NUP88 ANKRD49 RECQL YTHDC2 POU5F1 RNF17 ECT2 TRANK1 PRPF3 DGKK ATM DNAH8 PLS1 MYBL2 BRWD1

5.08e-0782014120gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000

USP34 SMG1 PDPR GNG13 CEP290 ANKRD49 YTHDC2 RO60 POU5F1 RNF17 ECT2 ARHGAP29 NAV2 SMARCC1 ATM FAR1 DNAH8

1.59e-0577614117gudmap_developingGonad_e14.5_ ovary_1000
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM7 ABCA13 EMC9 BDH1 RASSF6 TMEM132A WNK4

2.26e-061831447f3728b1a51951c7349f77a3e4d2671ca3a8d2a44
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA KALRN ABCA13 SLC6A17 TRANK1 TRPM3 DGKK

2.34e-0618414472cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA KALRN ABCA13 SLC6A17 TRANK1 TRPM3 DGKK

2.34e-061841447ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA KALRN ABCA13 SLC6A17 TRANK1 TRPM3 DGKK

2.34e-0618414472b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP6V1B1 TRPM7 ABCA13 EMC9 BDH1 RASSF6 WNK4

2.34e-0618414478939b6d795992775df0ff58ed1ec9d421a00bcc4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 TBC1D8 MYOF FGD4 ARHGAP29 NAV2 RIMBP2

2.89e-061901447bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 TBC1D8 MYOF FGD4 ARHGAP29 NAV2 RIMBP2

2.89e-061901447b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP6V1B1 KALRN TRPM7 ABCA13 RASSF6 TMEM132A WNK4

3.10e-0619214476fb56d062c35617b18b927704bf5fba894faed81
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGAP42 DOCK3 ZFP28 FHOD3 NWD2 CDCA5

1.14e-051551446cd7d95cbcad248670e531d80bb83c55e36ebc573
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POU6F2 DDC TRPM3 RASSF6 RIMBP2 PAX4

1.63e-0516514464b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCellControl-NK|Control / Disease group and Cell class

DOCK3 TBC1D8 WWC2 BCO2 NAV2 USP6NL

1.80e-051681446683d389c8a1e791bfc773e63148115a21a6566db
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TCERG1L SLC6A17 DDC TBC1D3B DGKK RIMBP2

1.93e-05170144698d13dbd76a826e47d55553f9d11f71c043b573e
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP9X CEP290 TRPM3 APOBEC2 RIMBP2 DAAM1

2.50e-051781446fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXN1 DDC RASSF6 RIMBP2 PAX4 WNK4

2.66e-051801446d553aba594f5304f1c09ff9c6d49b64cd7ee7850
ToppCell3'_v3-lymph-node_spleen-Myeloid_Monocytic-Nonclassical_monocytes|lymph-node_spleen / Manually curated celltypes from each tissue

LRRK2 TBC1D8 MYOF FGD4 ARHGAP29 MERTK

3.20e-051861446d7da5edb2ee36f96cdd7e27eb9afcc1cbfd52bb6
ToppCellCOVID-19-kidney-Mito-rich_Distal|kidney / Disease (COVID-19 only), tissue and cell type

LRRK2 FGD4 FEN1 NAV2 RIMBP2 WNK4

3.30e-0518714462ce8038d9d1302e850c1bb536e755598f77ba4b9
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ATP6V1B1 TCERG1L SLC6A17 DDC RASSF6 RIMBP2

3.40e-0518814461f912ea015f50570e848259d948a0ba682d64bb4
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP6V1B1 TRPM7 ABCA13 RASSF6 TMEM132A WNK4

3.50e-051891446e127e3be626bc513e151d41812f0b7adb89d5da6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRRK2 MYOF FGD4 RIMBP2 MERTK WNK4

3.50e-051891446e059be2965cca70ff5576df055d0af1775b76e00
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP6V1B1 TRPM7 ABCA13 RASSF6 TMEM132A WNK4

3.50e-051891446ff637ae0afdb1fdc67451be7e1e4fe575fbcfff4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 LRRK2 MYOF ARHGAP29 NAV2 RIMBP2

3.60e-0519014463fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 TBC1D8 MYOF FGD4 ARHGAP29 RIMBP2

3.71e-0519114462fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Hematologic-erythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFT140 SLC25A21 CEP290 FEN1 DAAM1 MYBL2

3.71e-05191144624ebc8d4a9fc3782510162e04fe586f7cb371eed
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 ECT2 RTKN2 FGD4 RIMBP2 WDR72

3.82e-05192144625378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

POU6F2 FEN1 CDCA5 PLS1 MYBL2 BRWD1

3.82e-051921446d6f656be2698bd215717d35f4e7ab727c08c61e0
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

TNPO1 USP34 USP9X RO60 SMARCC1 DYNC1H1

3.93e-051931446abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP6V1B1 KALRN TRPM7 ABCA13 RASSF6 WNK4

3.93e-051931446fa8bcf2a5ab7b08fae98a1466a936995142b4309
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 LRRK2 POU5F1 MYOF FGD4 ARHGAP29

4.05e-051941446e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellsevere-Myeloid-Immature_Neutrophils_1|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ABCA13 GBE1 ACAD8 AGL NAV2 ALDH3B1

4.16e-051951446becad890a420267ca41e98e61a8da343b51e1945
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

LRRK2 MYOF FGD4 NAV2 RIMBP2 WNK4

4.28e-05196144604f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellCOVID-19_Moderate-Non-classical_Monocyte|COVID-19_Moderate / disease group, cell group and cell class

LRRK2 TBC1D8 MYOF FGD4 MERTK ALDH3B1

4.28e-051961446256c557fa11414c9d2cbb1fcff33f482ee1c78ac
ToppCelldistal-3-Epithelial-Ionocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ATP6V1B1 EPPK1 FHOD3 RASSF6 MERTK WDR72

4.28e-0519614466ed146481dd04fb271eadc47d68eb3ae38986db6
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARHGAP42 MYOF NAV2 CHD6 PLS1 STEAP1

4.41e-051971446d6c9da7a3a6d2bcb13e2fc6605c8a59e7fb121c5
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARHGAP42 MYOF NAV2 CHD6 PLS1 STEAP1

4.41e-05197144680b05c8ad9c1edc5dea3236079372475431343fe
ToppCellsevere-Myeloid-Immature_Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ABCA13 GBE1 ACAD8 AGL NAV2 ALDH3B1

4.41e-0519714469599319dd1f80c81356a8624131566cc76d77d7e
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ATP6V1B1 SLC6A17 FHOD3 DDC RASSF6 WDR72

4.53e-0519814462591e08e3fbee86ac40f11becd8147d6d39fded6
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Polychromatic_Erythroblast|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

SLC25A21 DCUN1D5 ECT2 FEN1 CDCA5 MYBL2

4.66e-051991446fa698f00d2dad74d28b4696c8c23dce70f123e52
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating|1_mon / Sample Type, Dataset, Time_group, and Cell type.

EMC9 ECT2 RTKN2 FEN1 CDCA5 MYBL2

4.79e-052001446762442d125e594fede4506b72da15563b1d8798a
ToppCellSigmoid-T_cell-cycling_gd_T|T_cell / Region, Cell class and subclass

VAPB GBF1 ECT2 MYOF RASSF6 QSOX2

4.79e-0520014464e489ecf472857357d45e9f6c7a812aa48b72ebf
ToppCellControl-B_memory-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FHOD3 DGKK DAAM1 DNAH8 WDR72

5.19e-0512414453e987915026f503e8d072a837b6e7a34252e5c63
ToppCellControl-B_memory-6|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FHOD3 DGKK DAAM1 DNAH8 WDR72

8.05e-05136144594f23bef50c0beb54ed39b1a4b340f7aec4e75cd
ToppCellICU-SEP-Lymphocyte-T_NK-MAIT|ICU-SEP / Disease, Lineage and Cell Type

RPS2 POU5F1B TRANK1 ZNF726 PLS1

1.94e-041641445db863a44fc0dad5518c47fdbf64ea21d6f36f089
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN BDH1 GGCX RTKN2 MYBL2

1.99e-0416514450edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN BDH1 GGCX RTKN2 MYBL2

1.99e-041651445fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SLC25A21 MYOC ECT2 APOBEC2

2.08e-0490144472b800d26f1f06540fff35a57c23ca453b51edd8
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SLC25A21 MYOC ECT2 APOBEC2

2.08e-04901444cd2424a1b0a9264e91731691bda34dbd73867971
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SLC25A21 MYOC ECT2 APOBEC2

2.08e-04901444c96d653ab7761ecc0cd0835a5fc8ae6f9b151210
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ECT2 TBC1D3B RTKN2 CDCA5 MYBL2

2.11e-04167144550c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GNG13 RASSF6 PLA2G4A CHD6 MGAM2

2.16e-0416814458072d0496b7b730c4601009eaa69ec5366d26d73
ToppCellControl-B_cells-Activated_B_cells|Control / group, cell type (main and fine annotations)

DOCK2 RASSF6 ATM STEAP1B USP6NL

2.16e-041681445a7159a35fe37f8c241cf8d391debe271e0698105
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ECT2 TBC1D3B RTKN2 CDCA5 MYBL2

2.16e-041681445d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A17 DDC RASSF6 RIMBP2 PAX4

2.16e-04168144538ba7737ae0afffcbd3aa499403e83c24a922127
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TNPO1 DOCK2 PLD3 MYOF FEN1

2.16e-041681445a1755afa2cc50960ba60e07d84d61be429cdea72
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRK2 TBC1D8B YARS1 CUL5 PARVA

2.16e-041681445d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_mem-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

POU4F1 RASSF6 ZNF92 NAV2 DAAM1

2.23e-041691445e3ec9468141b6456398dca17dd8eeaabd2462710
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 ECT2 RTKN2 CDCA5 MYBL2

2.23e-041691445e7514956b2e4298222ec443f98b2f5289451786e
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

POU5F1 DDC BDH1 FEN1 MYBL2

2.23e-041691445dbf9b1d52b29bf4b60bd23012cc1ea82d344747f
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POU6F2 DDC RASSF6 RIMBP2 PAX4

2.29e-041701445985c2d5962100fab0d95bee39f382ccbe799331e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 LRRK2 SLC6A12 DNAH17 ARHGAP29

2.29e-0417014455d5f208682be21ed58320f5fc083a7898f8712da
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EECs|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RGS9 TBC1D8B TRPM3 DNAH17 RIMBP2

2.35e-041711445dd37e1693a5cfc42e40992d504f92048a8038b52
ToppCellInt-URO-Lymphocyte-B-B_memory|Int-URO / Disease, Lineage and Cell Type

RPS2 RASSF6 NAV2 DAAM1 DNAH8

2.41e-04172144538ebfb060c1c9ce9dea6b5833051c5bccb687e29
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP6V1B1 KALRN ABCA13 RASSF6 WNK4

2.41e-041721445bc1b889ac5e07b8324ae5837eca911f9c865e959
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP6V1B1 KALRN ABCA13 RASSF6 WNK4

2.41e-041721445ba70b6110b70afb1870e8dcaf58c507b8c7d918e
ToppCell3'_v3-bone_marrow-Lymphocytic_B-GC_B_(I)|bone_marrow / Manually curated celltypes from each tissue

IL31RA ECT2 RASSF6 PLA2G4A CDCA5

2.48e-04173144567f0f0bf88eab69987b71d96b864ed2b14975adb
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

POU6F2 TCERG1L LRRK2 RTKN2 TRPM3

2.48e-0417314459a2d42f8d9cb834856522661d524abb91c4637c5
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TCERG1L POU5F1 POU5F1B RNF17 WDR72

2.61e-0417514452fbffcb843f364645b99d1211698d96092abc5ef
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-stromal_related-Germ|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TCERG1L POU5F1 POU5F1B RNF17 WDR72

2.61e-041751445d0d5ae2a9357aa183ab720c891d86b80c9822930
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Follicular-7|TCGA-Thryoid / Sample_Type by Project: Shred V9

SLC6A17 NDUFA5 BDH1 NWD2 ACAD8

2.68e-0417614459a4cef3dc88f64a71b91ab4790ea19334afee3ee
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP6V1B1 POU5F1 RNF17 ZNF728 MYBL2

2.68e-041761445d5cee483d2a60f82fdc67ad447b589d022fe8c97
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-progenitor-Germ|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP6V1B1 POU5F1 RNF17 ZNF728 MYBL2

2.68e-041761445eea554ea75580f8dd5fefb57e7f33441ab86b884
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 ABCA13 LRRK2 TRPM3 ENPEP

2.90e-04179144558ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PFAS ECT2 FEN1 CDCA5 MYBL2

2.98e-04180144542f48e646fc6e72ad3cce72409ace3a0b64020a2
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

FHOD3 TRPM3 RASSF6 ENPEP WDR72

2.98e-041801445358923e4228035a3e90e2957392089219e90dcd7
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

FHOD3 TRPM3 RASSF6 ENPEP WDR72

2.98e-041801445864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c06-MKI67|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARHGAP42 GBF1 GBE1 TRPM3 GADL1

3.05e-041811445c18e5a3f5d99043fa3cb33e2ac33fa98cd15d3db
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HNF1A FHOD3 TRPM3 ENPEP WDR72

3.05e-0418114459542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RTKN2 MYOF WWC2 TRPM3 NAV2

3.05e-041811445b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FHOD3 TRPM3 FGD4 RIMBP2 WDR72

3.05e-041811445aa233b652921848af2257cc3687a7a09c3acfb67
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CATSPERE ABCA13 MYOF NAV2 PLS1

3.05e-041811445576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HNF1A FHOD3 TRPM3 ENPEP WDR72

3.05e-0418114458f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLD3 ECT2 MYOF CDCA5 WNK4

3.13e-04182144521dcab170ffeef89faa9fee5008568cb6e15c694
ToppCellEpithelial-lung_neuroendocrine_cell_(PNEC)|World / Lineage, Cell type, age group and donor

DOCK3 TCERG1L SLC6A17 DDC RIMBP2

3.13e-04182144557bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POU6F2 ABCA13 ECT2 CDCA5 MYBL2

3.13e-04182144511494a66d986297b837332ee9d382b71b9f22591
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

FHOD3 TRPM3 RASSF6 RIMBP2 WDR72

3.13e-0418214459d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCA13 TRPM3 RASSF6 ENPEP WDR72

3.21e-0418314456878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECT2 APOBEC2 FEN1 CDCA5 MYBL2

3.21e-041831445769a022fe8568ec49e66f792cc5777e713a7571c
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

POU6F2 ABCA13 ECT2 CDCA5 MYBL2

3.21e-0418314456c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 LRRK2 SLC6A12 DNAH17 ARHGAP29

3.21e-04183144592fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECT2 APOBEC2 FEN1 CDCA5 MYBL2

3.21e-041831445aac0695fafa59cabd920ee18b1139d3e00d898e8
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

ARHGAP42 ABCA13 LRRK2 TRPM3 ENPEP

3.29e-04184144551ed1ebfdef45149541917c66cbacad87072e51f
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARHGAP42 RTKN2 WWC2 PARVA NAV2

3.29e-04184144557c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRRK2 MYOF PLA2G4A RIMBP2 WNK4

3.29e-0418414458fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARHGAP42 RTKN2 WWC2 PARVA NAV2

3.29e-041841445d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA13 ECT2 RTKN2 CDCA5 MYBL2

3.38e-04185144547c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-Tuft-Tuft|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GNG13 RASSF6 TMEM132A SMARCC1 RIMBP2

3.38e-0418514451fbdc96da0623c3935ae9d29dcb4ba9c474e5c21
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-Tuft|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GNG13 RASSF6 TMEM132A SMARCC1 RIMBP2

3.38e-041851445b45487daac116e3d3d65ac2b0f81d1bf7d1a1914
ToppCellfacs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECT2 RTKN2 FEN1 DNAH8 CDCA5

3.46e-0418614459feef5936985e936b3d88f9d1bb012abb6468570
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RTKN2 MYOF TRPM3 RASSF6 NAV2

3.46e-0418614454e94158db52df41d71e67b02b9895a358eebee0f
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RTKN2 MYOF WWC2 TRPM3 NAV2

3.46e-0418614453aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellIPF-Lymphoid-B_Plasma|Lymphoid / Disease state, Lineage and Cell class

ECT2 RASSF6 MERTK CDCA5 MYBL2

3.46e-041861445f9c21daf905d0bb0e0e769ca4bb069ea4b1ba25b
DiseaseLeber Congenital Amaurosis

IFT140 CEP290 GUCY2D MERTK

2.88e-06221354C0339527
DiseaseGlycogen Storage Disease Type III

GBE1 AGL

2.08e-0521352C0017922
Diseaseintellectual developmental disorder with hypotonia, impaired speech, and dysmorphic facies (implicated_via_orthology)

TNPO1 TNPO2

2.08e-0521352DOID:0081262 (implicated_via_orthology)
DiseaseLeber congenital amaurosis (implicated_via_orthology)

CEP290 RDH14 GUCY2D

2.59e-05131353DOID:14791 (implicated_via_orthology)
DiseaseChromosome 11p11.2 Deletion Syndrome

EXT2 PHF21A

6.21e-0531352C1832588
Diseaseserum metabolite measurement

TNPO1 HNF1A POU6F2 DDC PHF21A LACTB SLC6A12 NWD2 ACAD8 DNAH17 GADL1 PCIF1 PLA2G4A ENPEP

1.14e-0494513514EFO_0005653
Diseasenephrotic syndrome type 20 (implicated_via_orthology)

TBC1D8B TBC1D8

1.24e-0441352DOID:0070357 (implicated_via_orthology)
DiseaseHepatitis

ARHGAP29 NAV2 WDR72

1.35e-04221353HP_0012115
DiseaseCrohn's disease

USP34 TCERG1L KALRN LRRK2 POU5F1 TRPM3 FEN1 PLA2G4A CHD6

2.04e-044411359EFO_0000384
Diseaseurinary pH measurement

KALRN WDR72

2.06e-0451352EFO_0010136
DiseaseDistal Renal Tubular Acidosis

ATP6V1B1 WDR72

2.06e-0451352C1704380
DiseaseOvarian Mucinous Adenocarcinoma

LRRK2 ALPK1 WNK4

3.83e-04311353C1335167
DiseaseMASA syndrome (implicated_via_orthology)

TRPM7 TRPM3

4.30e-0471352DOID:0060246 (implicated_via_orthology)
DiseaseDisorder of eye

MYOC CEP290 RGS9 PRPF3 GUCY2D MERTK

4.46e-042121356C0015397
DiseasePena-Shokeir syndrome type I

NUP88 GBE1

5.71e-0481352C1276035
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

HNF1A LRRK2 CILK1 ATM MERTK

6.10e-041481355C0279702
Diseaseserum alanine aminotransferase measurement

TNPO1 HNF1A GBF1 TRPM7 TBC1D8 TRANK1 PRPF3 SUPV3L1 FEN1 MERTK STEAP1B BRWD1

6.67e-0486913512EFO_0004735
Diseaseglucose metabolism decline measurement, cingulate cortex measurement

TBC1D8 TYW1

7.32e-0491352EFO_0007738, EFO_0009392
Diseaseretinitis pigmentosa (is_implicated_in)

IFT140 PRPF3 GUCY2D

8.79e-04411353DOID:10584 (is_implicated_in)
Diseasetheophylline measurement

LRRK2 NAV2

9.13e-04101352EFO_0021180
DiseaseCharcot-Marie-Tooth disease

YARS1 FGD4 DYNC1H1

9.44e-04421353cv:C0007959
Diseasemetabolite measurement

DDC LACTB SLC6A12 MYOF ACAD8 GADL1 PCIF1 RIMBP2 ENPEP

1.13e-035601359EFO_0004725
DiseaseRetinitis Pigmentosa

IFT140 PRPF3 GUCY2D MERTK

1.35e-031041354C0035334
Diseaseserum albumin measurement

TNPO1 DOCK3 HNF1A TMEM60 RASSF6 SMARCC1 STEAP1B QSOX2 WDR72

1.66e-035921359EFO_0004535
Diseasenon-high density lipoprotein cholesterol measurement

TNPO1 USP34 HNF1A LACTB TBC1D8 RASSF6 PCIF1 QSOX2 BRWD1 WDR72

1.68e-0371313510EFO_0005689
DiseaseMaturity onset diabetes mellitus in young

HNF1A PAX4

1.82e-03141352C0342276
Diseaseuric acid measurement

USP34 HNF1A TRPM7 RDH14 MYOF GUCY2D ALDH3B1 QSOX2 WDR72

2.03e-036101359EFO_0004761
DiseasePolydactyly

IFT140 USP9X CEP290 CILK1

2.08e-031171354C0152427
DiseaseLeber congenital amaurosis

CEP290 GUCY2D

2.39e-03161352cv:C0339527
DiseaseMalignant lymphoma, lymphocytic, intermediate differentiation, diffuse

ARHGAP29 ATM

2.39e-03161352C0334634
DiseaseMonogenic diabetes

HNF1A PAX4

2.39e-03161352C3888631
DiseaseGlycogen storage disease

GBE1 AGL

2.70e-03171352cv:C0017919
Diseaseprogression free survival, ovarian carcinoma

SLC25A21 FHOD3

3.03e-03181352EFO_0001075, EFO_0004920
Diseasereticulocyte measurement

ARHGAP42 USP34 USP9X PFAS RGS9 POU5F1 CUL5 TBC1D8 DNAH17 PCIF1 PLS1 MYBL2

3.33e-03105313512EFO_0010700
Diseaseplatelet measurement

EPPK1 KALRN LRRK2 TRPM3 FGD4 STEAP1B

3.36e-033151356EFO_0005036
DiseaseInfiltrating duct carcinoma of female breast

SMG1 TRPM7

4.12e-03211352C3165106
Diseasenephrotic syndrome

KALRN NWD2 RRP12

4.27e-03711353EFO_0004255

Protein segments in the cluster

PeptideGeneStartEntry
FMWLVDEAKKNLPLE

ADCK1

216

Q86TW2
MIRKLVAEKLNIPWN

AASDHPPT

66

Q9NRN7
KMPEILKTELDEWAA

CDCA5

221

Q96FF9
EWKMALFKPADVILD

BTN3A3

331

O00478
EDKWDFMRPIVLKLL

CUL5

16

Q93034
WRIVVPMTKDDALKE

CATSPERE

181

Q5SY80
WKSMIELNKHLPLEE

CATSPERE

811

Q5SY80
EWDQKELFPVDVMRK

ACAD8

66

Q9UKU7
ESIQAIAKKMWEELP

BDH1

251

Q02338
WMKDERVPKNLATQL

ALDH3B1

81

P43353
EELWPKFQQIMKDLT

ABCA13

2056

Q86UQ4
WLGKMLELPKAFLNE

DDC

121

P20711
IFIEQPLKMNLWKIA

BCO2

296

Q9BYV7
PENIIMLVLAWKLEA

DCUN1D5

81

Q9BTE7
MWEEPEIQAALKKLK

APOBEC2

156

Q9Y235
ELRTLIQEAKEMKWP

ALPK1

46

Q96QP1
DEWDSPELQKTRMKL

NWD2

91

Q9ULI1
PKFEELQKVLMEWIN

PARVG

41

Q9HBI0
MLDIFWGVKRPIQLK

RASSF6

91

Q6ZTQ3
KKLLEMLQEWLASLP

QSOX2

371

Q6ZRP7
WDLNAKLVEIPTKMR

RGS9

281

O75916
DELPKENWLKMLCRH

ECT2

776

Q9H8V3
PQLMTLKEKAIQVWD

OTOA

876

Q7RTW8
NMCKLRPLLQKWVEE

POU5F1B

196

Q06416
MIPVNKDPILEFWRK

SLC25A21

196

Q9BQT8
NMIALKPILQAWLEE

POU4F1

321

Q01851
LPMNEIEAWKAAEKK

PLD3

21

Q8IV08
KITLAAPNRKDMEEW

DGKK

286

Q5KSL6
APNRKDMEEWINIIK

DGKK

291

Q5KSL6
PVDPKKLIDSLEWMD

FAR1

171

Q8WVX9
DLLLKVDMWDKPQRI

MAGEE2

201

Q8TD90
KLDEGWVPLEIMIKF

SSB

41

P05455
WRKQLVNMLLPGDKI

MGAM2

746

Q2M2H8
KMPVKWIAIESLADR

MERTK

761

Q12866
IKRMIQIEWIKPELA

IL31RA

136

Q8NI17
ILLMKQCWAEQPELR

GUCY2D

781

Q02846
KWLQRGVMDPLDKVL

KIAA1109

4966

Q2LD37
MVALAKLWEAGKLDL

LACTB

171

P83111
MPELLEQLWKARAEK

FAM13B

841

Q9NYF5
EELMKLSPEELLLRW

PLS1

261

Q14651
MPKDSNLLLEDVTWK

PDPR

606

Q8NCN5
MAKGPVEIWLLDLLK

DNAH8

1646

Q96JB1
KFLLPELEKRMQEWE

FGD4

266

Q96M96
VIIDMRGSKWDLIKP

KALRN

96

O60229
RCQDQMLKKEEAIPW

PHF21A

531

Q96BD5
PLEKKLFAWDNLNMV

MYOC

481

Q99972
NEMGKLSKIWDLPLD

LRRK2

1286

Q5S007
TLLQEDPWRVAKMVK

HNF1A

106

P20823
MASKTIPELLKWIED

GNG13

26

Q9P2W3
LRMLEDWIKPENFQK

ENPEP

486

Q07075
QEKKMEKDPSRLLLW

ANKRD49

66

Q8WVL7
DWLLVRMKIRPFDKN

OOSP4B

16

A0A2R8Y4Y8
NMCKLRPLLQKWVEE

POU5F1

196

Q01860
RRQEKLKWEMQLPGA

PAX4

226

O43316
DKKWPNMCIEINRIL

ARHGAP29

786

Q52LW3
REAMFALPAEKKWQI

DAAM1

71

Q9Y4D1
MEKFLDPAIWFEKRL

ATM

2836

Q13315
AMAIPDKWIQLLKEF

GBE1

436

Q04446
LKWSEPNEEELIKFM

FEN1

296

P39748
WMLERKVVDKGSDPL

PCIF1

236

Q9H4Z3
LKWRMKPQLLQENLE

DOCK2

621

Q92608
ALLKWKAFPDRIMDV

DOCK3

611

Q8IZD9
RKNEWPLDKMCLSVE

DNAH17

4341

Q9UFH2
KWATMEELEKDPRIA

CHD6

331

Q8TD26
NWKEIMKVDPDDLPR

CEP290

6

O15078
VKPWSNIMEILEEKD

FHOD3

241

Q2V2M9
ELNPNKEPWRKMDLR

BRWD1

986

Q9NSI6
KEPWRKMDLRDQELV

BRWD1

991

Q9NSI6
LPIWVNKLDMEIERI

DYNC1H1

896

Q14204
PKINEWLTLVEKEMR

DYNC1H1

1696

Q14204
VAQWLRENPRLDKKM

GBF1

736

Q92538
EAKKLLKEAVVLPMW

KATNA1

216

O75449
VPKDKNLVMWRDWEE

EMC9

141

Q9Y3B6
KMIPEELEKQVWQAR

GADL1

246

Q6ZQY3
MLEDKWRNAYKTPLL

DHX37

946

Q8IY37
SLDWRKEPEIMKNII

IFT140

1256

Q96RY7
MALSKRELDELKPWI

PRPF3

1

O43395
PFKELLLAEKWAKMN

PLA2G4A

586

P47712
LMVLELPKRWGKNSE

NUP88

131

Q99567
KIAISDIRIPLMWKD

RTKN2

101

Q8IZC4
LDLGWKLLRIFPKEM

ATP6V1B1

471

P15313
DLAKLDDMINRPRWV

USP9X

71

Q93008
MPWQLPLEQREKKEA

RIMBP2

461

O15034
DNMKAPWELLELRVS

YARS1

81

P54577
QAPEAEKDKMVWEIL

TMEM132A

376

Q24JP5
WNDPDRMLLRDVKAL

SARAF

31

Q96BY9
NRKLWLEAMDGKEPI

ARHGAP42

361

A6NI28
KVLGNRWAEIAKMLP

MYBL2

151

P10244
NMIALKPILQAWLEE

POU4F2

311

Q12837
AQKIKPVLERWMAEA

POU6F2

571

P78424
WALNPAKIDKMQEEL

FOXN1

346

O15353
MQEELQKWKRKDPIA

FOXN1

356

O15353
KLNKMEIPIAWRKID

SMG1

2981

Q96Q15
MKKGLIPWEQAARLL

EPPK1

1026

P58107
VRNMELVKIIDWIPK

NAV2

2306

Q8IVL1
LKPDLFRLKDPQVWM

SLC6A12

271

P48065
LLPKAMDESVARKLW

RDH14

311

Q9HBH5
MKLKELERPAVQAWS

SEC31B

1

Q9NQW1
GLLTPDMLKQLEKEW

SUPV3L1

741

Q8IYB8
DPKLQELMKVLIDWI

PARVA

91

Q9NVD7
ARKMREWKLWEPLVE

NDUFA5

91

Q16718
MIALKPVLQAWLEEA

POU4F3

241

Q15319
KEVWKALLQEMPLTA

RO60

266

P10155
EEWLRPVMRKEKQVL

SMARCC1

216

Q92922
ENDLQPLLAWLKVME

RRP12

381

Q5JTH9
EELWKMKPRRNLEED

STEAP1

11

Q9UHE8
EEIWKMKPRRNLEDN

STEAP1B

11

Q6NZ63
EAVQLLRDMLQWDPK

CILK1

256

Q9UPZ9
LNEKLTPLKLIDSWM

RECQL

506

P46063
DIHIMELPKNPWEKL

RNF17

1321

Q9BXT8
VWEKPMDLKDRGDLN

TCERG1L

366

Q5VWI1
WSVLLNIEEMKLKNP

TBC1D3B

111

A6NDS4
LVSLLEQEKEPWMVK

ZFP28

276

Q8NHY6
RGEVWALLLEIPKMK

USP6NL

106

Q92738
LEQGKEPWNLKRHEM

ZNF92

56

Q03936
LMDLSPWRAKLQEIK

GGCX

506

P38435
EDPRKQWRGEQEKML

WWC2

86

Q6AWC2
IMLVLKLDEKAPWNW

TMEM60

21

Q9H2L4
MAWALKLPLADEVIE

TFCP2

1

Q12800
MWLKPEEVLLKNALK

TBC1D8B

1

Q0IIM8
EEVLLKNALKLWLME

TBC1D8B

6

Q0IIM8
WSVLLNIEEMKLKNP

TBC1D3F

111

A6NER0
MTKEWQLELPKLLIS

TRPM3

171

Q9HCF6
DLELEWVLGKMPRKE

PFAS

626

O15067
MWLKPEEVLLKNALK

TBC1D8

1

O95759
KLMPPLIQKWNELKD

TNPO2

561

O14787
RILMELDGPNWREKL

SPAG1

566

Q07617
LDWKRASVVVPEEKM

EXT2

356

Q93063
LEQGKEPWNMKRHEL

ZNF728

56

P0DKX0
QMLPKLEWTEELELQ

WDR72

1026

Q3MJ13
TLLEQEKEPWMVVRK

ZNF780A

56

O75290
PLIQKWNMLKDEDKD

TNPO1

576

Q92973
WNMLKDEDKDLFPLL

TNPO1

581

Q92973
DIPLSLMNDWKDEFK

ZNF512B

86

Q96KM6
DLIICLEKEKEPWNM

ZNF726

51

A6NNF4
KDVNCLEPWLIKEMD

YTHDC2

456

Q9H6S0
LLEKMQDSRQKAVWP

USP41

106

Q3LFD5
VLPDWSMSEEEKLKR

ZCCHC18

71

P0CG32
KWKMENDRLPVELHQ

ZNF474

246

Q6S9Z5
TPKLDKMLDPQVWRE

SLC6A17

286

Q9H1V8
WKEAKPEDLMDSKLR

VAPB

106

O95292
EKPTMLQWIELLTKQ

USP34

2321

Q70CQ2
RWKMDQPEMILKEAI

TYW1

436

Q9NV66
EAKLDKGARMLWELA

TRANK1

846

O15050
EDKEWMPVTKLGRLV

RPS2

56

P15880
WSVLLNIEEMKLKNP

TBC1D3G

111

Q6DHY5
DDGEKPGLKLWLRME

WNK4

446

Q96J92
WSVLLNIEEMKLKNP

TBC1D3K

111

A0A087X1G2
KPEVILQLLLKEWQM

TRPM7

116

Q96QT4
VLPDWNMSEEEKLKR

ZCCHC12

71

Q6PEW1
DLMTCLEQRKEPWKV

ZNF736

51

B4DX44
MNSIRKIIWEDIFPK

AGL

281

P35573
VKLNSEMDITPKLLW

MYOF

1236

Q9NZM1