Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	D-glucose:sodium symporter activity	SLC5A9 SLC5A1 SLC5A4	1.62e-06	7	73	3	GO:0005412
GeneOntologyMolecularFunction	carbohydrate:monoatomic cation symporter activity	SLC5A9 SLC5A1 SLC5A4	3.07e-05	17	73	3	GO:0005402
GeneOntologyMolecularFunction	low-affinity D-glucose:sodium symporter activity	SLC5A9 SLC5A4	3.95e-05	3	73	2	GO:0005362
GeneOntologyMolecularFunction	D-glucose transmembrane transporter activity	SLC5A9 SLC5A1 SLC5A4	1.02e-04	25	73	3	GO:0055056
GeneOntologyMolecularFunction	hexose transmembrane transporter activity	SLC5A9 SLC5A1 SLC5A4	1.02e-04	25	73	3	GO:0015149
GeneOntologyMolecularFunction	monosaccharide transmembrane transporter activity	SLC5A9 SLC5A1 SLC5A4	1.29e-04	27	73	3	GO:0015145
GeneOntologyMolecularFunction	sugar transmembrane transporter activity	SLC5A9 SLC5A1 SLC5A4	1.60e-04	29	73	3	GO:0051119
GeneOntologyMolecularFunction	carbohydrate transmembrane transporter activity	SLC5A9 SLC5A1 SLC5A4	4.86e-04	42	73	3	GO:0015144
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	STIM1 CNNM2 SLC9A3 SLC5A9 KCNS2 SLC5A1 SLC5A4	1.54e-03	465	73	7	GO:0046873
GeneOntologyMolecularFunction	symporter activity	SLC22A18 SLC5A9 SLC5A1 SLC5A4	2.23e-03	150	73	4	GO:0015293
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	STIM1 GABRD CNNM2 SLC9A3 SLC5A9 KCNS2 HTR3D SLC5A1 SLC5A4	2.34e-03	793	73	9	GO:0015075
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	STIM1 CNNM2 SLC9A3 SLC5A9 KCNS2 HTR3D SLC5A1 SLC5A4	2.87e-03	664	73	8	GO:0008324
GeneOntologyMolecularFunction	tau-protein kinase activity	MARK3 MARK2	2.90e-03	22	73	2	GO:0050321
GeneOntologyMolecularFunction	microtubule plus-end binding	STIM1 APC	2.90e-03	22	73	2	GO:0051010
GeneOntologyMolecularFunction	solute:sodium symporter activity	SLC5A9 SLC5A1 SLC5A4	3.26e-03	81	73	3	GO:0015370
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC9A3 SLC5A9 SLC5A1 SLC5A4	3.57e-03	171	73	4	GO:0015081
Domain	Na/solute_symporter_CS	SLC5A9 SLC5A1 SLC5A4	3.30e-06	8	74	3	IPR018212
Domain	NA_SOLUT_SYMP_1	SLC5A9 SLC5A1 SLC5A4	9.63e-06	11	74	3	PS00456
Domain	NA_SOLUT_SYMP_2	SLC5A9 SLC5A1 SLC5A4	1.28e-05	12	74	3	PS00457
Domain	SSF	SLC5A9 SLC5A1 SLC5A4	1.28e-05	12	74	3	PF00474
Domain	Na/solute_symporter	SLC5A9 SLC5A1 SLC5A4	1.28e-05	12	74	3	IPR001734
Domain	NA_SOLUT_SYMP_3	SLC5A9 SLC5A1 SLC5A4	1.28e-05	12	74	3	PS50283
Domain	MARK/par1	MARK3 MARK2	9.24e-05	4	74	2	IPR033624
Domain	KA1_dom	MARK3 MARK2	1.54e-04	5	74	2	IPR001772
Domain	KA1	MARK3 MARK2	1.54e-04	5	74	2	PF02149
Domain	KA1	MARK3 MARK2	1.54e-04	5	74	2	PS50032
Domain	-	MARK3 MARK2	1.54e-04	5	74	2	3.30.310.80
Domain	KA1/Ssp2_C	MARK3 MARK2	3.21e-04	7	74	2	IPR028375
Domain	ARM-like	SCYL2 APC TOGARAM1 COPG2 MN1 STAG3	7.03e-04	270	74	6	IPR011989
Domain	-	SCYL2 APC TOGARAM1 COPG2 STAG3	1.88e-03	222	74	5	1.25.10.10
Domain	ARM-type_fold	SCYL2 UBR4 APC TOGARAM1 COPG2 STAG3	2.25e-03	339	74	6	IPR016024
Domain	PDZ	APBA2 MAGI3 FRMPD3 PDZD2	2.38e-03	141	74	4	PF00595
Domain	Ca/CaM-dep_Ca-dep_prot_Kinase	MARK3 PSKH1 MARK2	2.59e-03	69	74	3	IPR020636
Domain	HEAT_REPEAT	SCYL2 TOGARAM1 COPG2	2.70e-03	70	74	3	PS50077
Domain	PDZ	APBA2 MAGI3 FRMPD3 PDZD2	2.83e-03	148	74	4	SM00228
Domain	KRAB	ZNF705A ZNF816 ZNF705B ZNF705D ZNF287 ZNF705G	2.95e-03	358	74	6	PS50805
Domain	KRAB	ZNF705A ZNF816 ZNF705B ZNF705D ZNF287 ZNF705G	2.95e-03	358	74	6	PF01352
Domain	-	APBA2 MAGI3 FRMPD3 PDZD2	2.97e-03	150	74	4	2.30.42.10
Domain	PDZ	APBA2 MAGI3 FRMPD3 PDZD2	3.05e-03	151	74	4	PS50106
Domain	PDZ	APBA2 MAGI3 FRMPD3 PDZD2	3.12e-03	152	74	4	IPR001478
Domain	KRAB	ZNF705A ZNF816 ZNF705B ZNF705D ZNF287 ZNF705G	3.42e-03	369	74	6	SM00349
Domain	KRAB	ZNF705A ZNF816 ZNF705B ZNF705D ZNF287 ZNF705G	3.47e-03	370	74	6	IPR001909
Domain	UBA	MARK3 MARK2	6.27e-03	30	74	2	SM00165
Pathway	REACTOME_CELLULAR_HEXOSE_TRANSPORT	SLC5A9 SLC5A1 SLC5A4	5.50e-05	19	56	3	MM14718
Pathway	REACTOME_CELLULAR_HEXOSE_TRANSPORT	SLC5A9 SLC5A1 SLC5A4	7.51e-05	21	56	3	M27058
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ZC3H11A UBR4 ANKRD17 COPG2 MCM5 TNKS1BP1 BIRC6 LARP7 TASOR2 SON	1.41e-06	653	75	10	22586326
Pubmed	miR-126 regulates glycogen trophoblast proliferation and DNA methylation in the murine placenta.	CDKN1C PEG3 EMCN	2.71e-06	13	75	3	30771304
Pubmed	Fusobacterium nucleatum Promotes Metastasis in Colorectal Cancer by Activating Autophagy Signaling via the Upregulation of CARD3 Expression.	RIPK2 APC	4.59e-06	2	75	2	31903123
Pubmed	Decreased NHE3 expression in colon cancer is associated with DNA damage, increased inflammation and tumor growth.	SLC9A3 APC	4.59e-06	2	75	2	36042372
Pubmed	Parent-of-origin tumourigenesis is mediated by an essential imprinted modifier in SDHD-linked paragangliomas: SLC22A18 and CDKN1C are candidate tumour modifiers.	CDKN1C SLC22A18	4.59e-06	2	75	2	27402879
Pubmed	Loss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis.	MARK3 MARK2	4.59e-06	2	75	2	20733003
Pubmed	Genome imprinting regulated by the mouse Polycomb group protein Eed.	CDKN1C SLC22A18 PEG3	7.68e-06	18	75	3	12627233
Pubmed	Increased intestinal permeability and downregulation of absorptive ion transporters Nhe3, Dra, and Sglt1 contribute to diarrhea during Clostridioides difficile infection.	SLC9A3 SLC5A1	1.37e-05	3	75	2	37350393
Pubmed	Antibodies to a renal Na+/glucose cotransport system localize to the apical plasma membrane domain of polar mouse embryo blastomeres.	SLC5A9 SLC5A1	1.37e-05	3	75	2	1702069
Pubmed	A relay mechanism between EB1 and APC facilitate STIM1 puncta assembly at endoplasmic reticulum-plasma membrane junctions.	STIM1 APC	1.37e-05	3	75	2	23871111
Pubmed	Intestinal function of gene-targeted mice lacking serum- and glucocorticoid-inducible kinase 1.	SLC9A3 SLC5A1	1.37e-05	3	75	2	16410368
Pubmed	Differential regulation of mouse kidney sodium-dependent transporters mRNA by cadmium.	SLC5A1 SLC5A4	1.37e-05	3	75	2	11749115
Pubmed	Transcriptional regulation of NHE3 and SGLT1 by the circadian clock protein Per1 in proximal tubule cells.	SLC9A3 SLC5A1	1.37e-05	3	75	2	26377793
Pubmed	Ablation of p57+ Quiescent Cancer Stem Cells Suppresses Recurrence after Chemotherapy of Intestinal Tumors.	CDKN1C APC	1.37e-05	3	75	2	36880956
Pubmed	Post-oral appetite stimulation by sugars and nonmetabolizable sugar analogs.	SLC5A1 SLC5A4	1.37e-05	3	75	2	23926132
Pubmed	PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling.	MARK3 MARK2	1.37e-05	3	75	2	11433294
Pubmed	Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.	CDKN1C SLC22A18 SERPINF2	1.89e-05	24	75	3	20705733
Pubmed	Microarray expression profiling of tissues from mice with uniparental duplications of chromosomes 7 and 11 to identify imprinted genes.	CDKN1C SLC22A18 PEG3	1.89e-05	24	75	3	11668390
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	SCYL2 STIM1 MARK3 APC ANKRD17 MAGI3 COPG2 TNKS1BP1 MARK2	2.16e-05	708	75	9	39231216
Pubmed	The Kcnq1ot1 long non-coding RNA affects chromatin conformation and expression of Kcnq1, but does not regulate its imprinting in the developing heart.	CDKN1C SLC22A18	2.75e-05	4	75	2	23028363
Pubmed	Gut microbial metabolism drives transformation of MSH2-deficient colon epithelial cells.	RIPK2 APC	2.75e-05	4	75	2	25036629
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	SCYL2 STIM1 MARK3 CRYBG1 MAGI3 COPG2 TNKS1BP1 MARK2	3.00e-05	565	75	8	25468996
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	VPS4B UBR4 APC ANKRD17 COPG2 TNKS1BP1 BIRC6	3.39e-05	418	75	7	34709266
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	TRIM46 MARK3 VPS13C APC MAGI3 MARK2 MTCH1	4.05e-05	430	75	7	32581705
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	STIM1 ZC3H11A DSCAM VPS13C APC MUC16 COPG2 BIRC6 TASOR2	4.46e-05	777	75	9	35844135
Pubmed	Multipoint analysis of human chromosome 11p15/mouse distal chromosome 7: inclusion of H19/IGF2 in the minimal WT2 region, gene specificity of H19 silencing in Wilms' tumorigenesis and methylation hyper-dependence of H19 imprinting.	CDKN1C SLC22A18	4.57e-05	5	75	2	10369881
Pubmed	Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2.	MARK3 MARK2	4.57e-05	5	75	2	18626018
Pubmed	In vitro culture increases the frequency of stochastic epigenetic errors at imprinted genes in placental tissues from mouse concepti produced through assisted reproductive technologies.	CDKN1C PEG3	4.57e-05	5	75	2	24337315
Pubmed	HEY1 functions are regulated by its phosphorylation at Ser-68.	MARK3 APC TNKS1BP1 BIRC6	5.47e-05	95	75	4	27129302
Pubmed	Role of individual MARK isoforms in phosphorylation of tau at Ser²⁶² in Alzheimer's disease.	MARK3 MARK2	6.84e-05	6	75	2	23666762
Pubmed	Spatiotemporal reprogramming of differentiated cells underlies regeneration and neoplasia in the intestinal epithelium.	CDKN1C APC	6.84e-05	6	75	2	35314700
Pubmed	An EB1-binding motif acts as a microtubule tip localization signal.	STIM1 APC	6.84e-05	6	75	2	19632184
Pubmed	New role for hPar-1 kinases EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases.	MARK3 MARK2	6.84e-05	6	75	2	16980613
Pubmed	Blocked transcription through KvDMR1 results in absence of methylation and gene silencing resembling Beckwith-Wiedemann syndrome.	CDKN1C SLC22A18	6.84e-05	6	75	2	28428215
Pubmed	Placental growth retardation due to loss of imprinting of Phlda2.	CDKN1C SLC22A18	6.84e-05	6	75	2	15327781
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	ZC3H11A RTL9 CRYBG1 MCM5 TNKS1BP1 BIRC6 TASOR2	6.98e-05	469	75	7	27634302
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	MARK3 SHCBP1 APC MARK2	7.22e-05	102	75	4	15778465
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ZC3H11A MARK3 NTHL1 APC ANKRD17 CRYBG1 COPG2 MCM5 MARK2 SIX4 LARP7 SON	8.19e-05	1497	75	12	31527615
Pubmed	Regulation of the polarity kinases PAR-1/MARK by 14-3-3 interaction and phosphorylation.	MARK3 MARK2	9.57e-05	7	75	2	16968750
Pubmed	Identification and functional analysis of a novel cyclin e/cdk2 substrate ankrd17.	ANKRD17 MCM5	9.57e-05	7	75	2	19150984
Pubmed	The two-domain hypothesis in Beckwith-Wiedemann syndrome: autonomous imprinting of the telomeric domain of the distal chromosome 7 cluster.	CDKN1C SLC22A18	9.57e-05	7	75	2	15640248
Pubmed	Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions.	ADGRF4 ADGRG4	1.27e-04	8	75	2	12435584
Pubmed	Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions.	MARK3 MARK2	1.27e-04	8	75	2	22298430
Pubmed	Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes.	CDKN1C SLC22A18	1.27e-04	8	75	2	16702402
Pubmed	Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting.	CDKN1C PEG3	1.27e-04	8	75	2	15215868
Pubmed	Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.	APC EMCN	1.27e-04	8	75	2	29170395
Pubmed	DNA sequence and analysis of human chromosome 8.	RIPK2 ZNF705B ZNF705G	1.55e-04	48	75	3	16421571
Pubmed	Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity.	MARK3 MARK2	1.64e-04	9	75	2	18562307
Pubmed	AQP5 enriches for stem cells and cancer origins in the distal stomach.	SLC9A3 APC	1.64e-04	9	75	2	32025032
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	STIM1 ZC3H11A UBR4 SON	1.84e-04	130	75	4	35545047
Pubmed	Two distinct mechanisms of silencing by the KvDMR1 imprinting control region.	CDKN1C SLC22A18	2.04e-04	10	75	2	18079696
Pubmed	The Spatiotemporal Expression of Notch1 and Numb and Their Functional Interaction during Cardiac Morphogenesis.	CDKN1C EMCN	2.04e-04	10	75	2	34571841
Pubmed	An imprinted gene network that controls mammalian somatic growth is down-regulated during postnatal growth deceleration in multiple organs.	CDKN1C PEG3	2.04e-04	10	75	2	18448610
Pubmed	Sequence-based structural features between Kvlqt1 and Tapa1 on mouse chromosome 7F4/F5 corresponding to the Beckwith-Wiedemann syndrome region on human 11p15.5: long-stretches of unusually well conserved intronic sequences of kvlqt1 between mouse and human.	CDKN1C SLC22A18	2.04e-04	10	75	2	10907850
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	ZC3H11A MARK3 MARK2 BIRC6 MTCH1 LARP7 SON CENPQ	2.31e-04	759	75	8	35915203
Pubmed	Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation.	CDKN1C SLC22A18	2.49e-04	11	75	2	15516931
Pubmed	The imprinted domain in mouse distal Chromosome 7: reagents for mutagenesis and sequencing.	CDKN1C SLC22A18	2.49e-04	11	75	2	9922400
Pubmed	Genomic imprinting in Dicer1-hypomorphic mice.	CDKN1C PEG3	2.49e-04	11	75	2	16575173
Pubmed	Mechanism of imprinting on mouse distal chromosome 7.	CDKN1C SLC22A18	2.49e-04	11	75	2	10036981
Pubmed	Role of cell and matrix-bound VEGF isoforms in lens development.	CDKN1C EMCN	2.49e-04	11	75	2	18757513
Pubmed	A murine even-skipped homologue, Evx 1, is expressed during early embryogenesis and neurogenesis in a biphasic manner.	CDKN1C SLC22A18	2.99e-04	12	75	2	1971786
Pubmed	Peg1/Mest in obese adipose tissue is expressed from the paternal allele in an isoform-specific manner.	CDKN1C PEG3	2.99e-04	12	75	2	17182038
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	MARK3 VPS4B SHCBP1 APBA2 APC ANKRD17 MAGI3 MCM5 MARK2	3.09e-04	1005	75	9	19615732
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	SCYL2 VPS13C UBR4 RTL9	3.43e-04	153	75	4	10718198
Pubmed	Kcnq1ot1 noncoding RNA mediates transcriptional gene silencing by interacting with Dnmt1.	CDKN1C SLC22A18	3.52e-04	13	75	2	20573698
Pubmed	New sequence variants associated with bone mineral density.	HROB MARK3	4.11e-04	14	75	2	19079262
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	MARK3 NTHL1 SHCBP1 UBR4 RIPK2 COPG2 MCM5 MARK2 QRICH2 SON	4.26e-04	1284	75	10	17353931
Pubmed	Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density.	MAGI3 PDZD2	4.73e-04	15	75	2	23782696
Pubmed	Sequence-ready 1-Mb YAC, BAC and cosmid contigs covering the distal imprinted region of mouse chromosome 7.	CDKN1C SLC22A18	4.73e-04	15	75	2	10691133
Pubmed	H19 acts as a trans regulator of the imprinted gene network controlling growth in mice.	CDKN1C PEG3	4.73e-04	15	75	2	19762426
Pubmed	Annotation and analysis of 10,000 expressed sequence tags from developing mouse eye and adult retina.	ANKRD17 SON	4.73e-04	15	75	2	14519200
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	STIM1 MARK3 RIPK2 APC ANKRD17 MAGI3 TNKS1BP1 MARK2	5.34e-04	861	75	8	36931259
Pubmed	Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1.	CDKN1C SLC22A18	5.40e-04	16	75	2	12410230
Pubmed	Modifier genes and protective alleles in humans and mice.	APC TUB	5.40e-04	16	75	2	12787792
Pubmed	Sequence and comparative analysis of the mouse 1-megabase region orthologous to the human 11p15 imprinted domain.	CDKN1C SLC22A18	6.11e-04	17	75	2	11076855
Pubmed	Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression.	ANKRD17 COPG2	6.11e-04	17	75	2	12747765
Pubmed	Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.	MARK3 RIPK2 MARK2	6.52e-04	78	75	3	17192257
Pubmed	Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.	VKORC1L1 SERPINF2	6.87e-04	18	75	2	24068962
Pubmed	Six1 is required for signaling center formation and labial-lingual asymmetry in developing lower incisors.	CDKN1C SIX4	6.87e-04	18	75	2	32243674
Pubmed	Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.	STIM1 SLC22A18 VKORC1L1 UBR4 MTCH1 TASOR2	7.39e-04	499	75	6	22810586
Pubmed	Gene density and transcription influence the localization of chromatin outside of chromosome territories detectable by FISH.	CDKN1C SLC22A18	7.66e-04	19	75	2	12473685
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	ZC3H11A SHCBP1 APC TNKS1BP1 MARK2 SON	7.70e-04	503	75	6	16964243
Pubmed	Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2.	STIM1 ZC3H11A MCM5 LARP7 SON	7.79e-04	333	75	5	36779763
Pubmed	Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms.	MARK3 MARK2	8.50e-04	20	75	2	18227155
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	ZC3H11A PEG3 TASOR2	8.67e-04	86	75	3	37253089
Pubmed	The imprinted Phlda2 gene regulates extraembryonic energy stores.	CDKN1C SLC22A18	1.03e-03	22	75	2	19884348
Pubmed	Sequence and functional comparison in the Beckwith-Wiedemann region: implications for a novel imprinting centre and extended imprinting.	CDKN1C SLC22A18	1.03e-03	22	75	2	11063728
Pubmed	Identification and characterisation of imprinted genes in the mouse.	CDKN1C PEG3	1.13e-03	23	75	2	15163367
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	TRIM46 HECTD2 UBR4	1.16e-03	95	75	3	29643511
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	STIM1 CNNM2 MARK3 COPG2 MARK2 MTCH1 LARP7	1.21e-03	754	75	7	33060197
Pubmed	Upregulation of imprinted genes in mice: an insight into the intensity of gene expression and the evolution of genomic imprinting.	CDKN1C PEG3	1.23e-03	24	75	2	20168089
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ZC3H11A SHCBP1 ANKRD17 TNKS1BP1 MARK2 MN1 SON	1.41e-03	774	75	7	15302935
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	MARK3 VPS4B APC ANKRD17 COPG2 MCM5 TNKS1BP1 MARK2 LARP7	1.43e-03	1247	75	9	27684187
Pubmed	Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.	CDKN1C NTHL1 RIPK2 SPATA32	1.59e-03	231	75	4	21048031
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SCYL2 GABRD DSCAM HECTD2 UBR4 PEG3 APBA2 APC MAGI3	1.76e-03	1285	75	9	35914814
Pubmed	The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.	ADGRF4 ADGRG4	1.79e-03	29	75	2	15203201
Pubmed	Disruption of parental-specific expression of imprinted genes in uniparental fetuses.	CDKN1C PEG3	1.79e-03	29	75	2	16987518
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	VPS4B APC ANKRD17 MARK2	1.89e-03	242	75	4	34011540
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZC3H11A MARK3 PEG3 SON PDZD2	1.89e-03	407	75	5	12693553
Pubmed	14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK.	MARK3 MARK2	1.92e-03	30	75	2	16306228
Cytoband	11p15.5	STIM1 CDKN1C SLC22A18 TUB	4.38e-05	118	75	4	11p15.5
Cytoband	Ensembl 112 genes in cytogenetic band chr22q12	MCM5 MN1 SLC5A1 SLC5A4	6.12e-04	235	75	4	chr22q12
Cytoband	22q12.3	SLC5A1 SLC5A4	1.35e-03	33	75	2	22q12.3
Cytoband	6p12.3	ADGRF4 CENPQ	1.60e-03	36	75	2	6p12.3
Cytoband	8p23.1	ZNF705B ZNF705D ZNF705G	2.09e-03	154	75	3	8p23.1
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	STIM1 CDKN1C SLC22A18 OR51G1 TUB	2.34e-03	564	75	5	chr11p15
GeneFamily	Solute carriers	SLC22A18 SLC9A3 SLC5A9 MTCH1 SLC5A1 SLC5A4	1.01e-03	395	53	6	752
GeneFamily	PDZ domain containing	APBA2 MAGI3 FRMPD3 PDZD2	1.02e-03	152	53	4	1220
GeneFamily	CD molecules\|Mucins	MUC16 EMCN	1.71e-03	21	53	2	648
Disease	visual impairment and progressive phthisis bulbi (implicated_via_orthology)	MARK3 MARK2	3.32e-05	4	70	2	DOID:0070356 (implicated_via_orthology)
Disease	nucleus accumbens volume change measurement	DSCAM MUC16	3.01e-04	11	70	2	EFO_0021493
Disease	uric acid measurement	TRIM46 CNNM2 DSCAM ZNF816 SLC5A9 BIRC6 QRICH2	6.06e-04	610	70	7	EFO_0004761
Disease	Polyposis, Adenomatous Intestinal	NTHL1 APC	6.52e-04	16	70	2	C2713442
Disease	Familial Intestinal Polyposis	NTHL1 APC	6.52e-04	16	70	2	C2713443
Disease	Adenomatous Polyposis Coli	NTHL1 APC	7.37e-04	17	70	2	C0032580
Disease	Schizophrenia	GABRD CDKN1C CNNM2 APBA2 APC HTR3D ADGRF4 MARK2	1.14e-03	883	70	8	C0036341
Disease	urate measurement	TRIM46 MARK3 ZNF816 SLC5A9 SERPINF2 BIRC6 QRICH2 SLC5A1	1.25e-03	895	70	8	EFO_0004531
Disease	eye color	EYS APBA2 MUC16	1.30e-03	90	70	3	EFO_0003949

Protein segments in the cluster

Peptide	Gene	Start	Entry
LSKSTRDHLQTMMES	CENPQ	76	Q7L2Z9
TARSMVSTIMKFLDS	BIRC6	3121	Q9NR09
VTSLSPSRSMDLEMK	CNTLN	1081	Q9NXG0
ATSIAMSRMSLSSFS	SERPINF2	396	P08697
SLPRVEDAMSTSMSK	ADGRG4	536	Q8IZF6
EDAMSTSMSKETSSK	ADGRG4	541	Q8IZF6
TSVVMSFSILMSSKS	ADGRF4	381	Q8IZF3
AEIKMSLSMTSITSA	APBA2	231	Q99767
SLMGIKMTTVALSST	ANKRD17	1831	O75179
MSGKNMRLSSLALSS	ATP8B2	1161	P98198
RMIIESMLTSSSTLL	QRICH2	1176	Q9H0J4
SMLTSSSTLLSMSMA	QRICH2	1181	Q9H0J4
TTASSETSMDFTMAK	MUC16	1061	Q8WXI7
KMSLMSTATFLTSKD	EMCN	71	Q9ULC0
KRTTSVSKMERMDSS	MAGI3	221	Q5TCQ9
SDLMNSDLTSKMTTD	EYS	1676	Q5T1H1
DASPSSIRSLKSDMM	MCM5	131	P33992
TSMDASSSEMKAPVL	HECTD2	106	Q5U5R9
VSMAASSSMKNLHRS	PSKH1	356	P11801
IHTLSSMESSVLLSM	OR51G1	106	Q8NGK1
QEMSRSFSMAKLASS	PDZD2	2156	O15018
SSCLEMLSTSSMSLD	FAM205A	136	Q6ZU69
KVKSLMASLTNMSRS	KCNS2	451	Q9ULS6
MDTSNTSISKMKRSR	LARP7	241	Q4G0J3
MIKSLTRSTMDASVV	HROB	501	Q8N3J3
TVLTMTTLMVSARSS	GABRD	286	O14764
VMTSATKIMSALGSN	LRIT3	256	Q3SXY7
EMRKAMSVSSLSSLS	PEG3	421	Q9GZU2
MSDASLRSTSTMERL	CDKN1C	1	P49918
RPEVSMMSSSASKNL	FRMPD3	1026	Q5JV73
GSSAVMSTAIMATLL	GPAT2	456	Q6NUI2
SSSALVSSLHMMKIS	COPG2	156	Q9UBF2
RSLRFTWSMKTTSSM	MARK2	691	Q7KZI7
RSLRFTWSMKTTSSM	MARK3	656	P27448
ISFSGMSLSDTMTLR	CRYBG1	996	Q9Y4K1
NTSLSMSKDDMSSTL	RNASE11	61	Q8TAA1
MSKDDMSSTLLTFRS	RNASE11	66	Q8TAA1
ETMLDSLSFVMLTSK	CYP8B1	141	Q9UNU6
MAVSTVFSTSSLMLA	SDHAF2	1	Q9NX18
AVKSAMSTIDLDSLM	MN1	1206	Q10571
EMLMSKNTRTSDTLS	DSCAM	1636	O60469
LMSNALSTVTRGSMK	MTCH1	156	Q9NZJ7
LSASLMRDTASGAMS	RTL9	666	Q8NET4
MHSTSLMLSSPTLKR	TAS2R16	271	Q9NYV7
TSIMDALVRISTSMK	TRIM46	11	Q7Z4K8
ASSSTMSLKKNMSAH	RGS22	1246	Q8NE09
ESGMTALSARMLTRS	NTHL1	6	P78549
SATTVRYTMKMLASS	SLC9A3	331	P48764
SSLAMASSSRMDLPS	SPATA32	246	Q96LK8
LSNSESKATSSLMML	SIX4	726	Q9UIU6
MLASLMSSLTSIFNS	SLC5A4	386	Q9NY91
TKDLTDTLMDNMSSL	SCYL2	716	Q6P3W7
MAALMSSLTSIFNSS	SLC5A9	391	Q2M3M2
MTMHTTMTTLTLTSL	MT-ND5	1	P03915
SSTMMAGLLRSLLTD	SHCBP1	336	Q8NEM2
MHLSRTSTKEMSDNL	TDRD7	201	Q8NHU6
NTTMTGTVLKMTDRS	STIM1	171	Q13586
SMLIKAVSTSDTGTM	SLC22A18	351	Q96BI1
MASMSIVKATSNTIS	HTR3D	136	Q70Z44
DKDDMSRTLLAMSSS	APC	326	P25054
LMASRMDKTPQSSDS	CNNM2	816	Q9H8M5
MSDMLRSLSNTKPTV	VPS4B	411	O75351
SMHPITRKDASTSMT	ZNF705A	91	Q6ZN79
TRKDASTSMTMENSL	ZNF705A	96	Q6ZN79
MLASSKRMNSSSRSQ	ZNF287	1	Q9HBT7
FRHTSTLAAMKLMTS	STAG3	231	Q9UJ98
RMMSLSQSRSSKSAP	RIPK2	171	O43353
SSSQMSMKTRRLSSA	ZC3H11A	746	O75152
MKVSTLRESSAMASP	TNKS1BP1	1	Q9C0C2
SRASLMKMESTVSIT	nan	296	Q9UF83
LSLSTSKLEQMMEAS	VPS13C	2136	Q709C8
SMHPITRKDASTSMT	ZNF705G	91	A8MUZ8
TRKDASTSMTMENSL	ZNF705G	96	A8MUZ8
SAVAALILMTSSIMS	VKORC1L1	106	Q8N0U8
SMHPIIRKDTSTSMT	ZNF705B	91	P0CI00
IRKDTSTSMTMENSL	ZNF705B	96	P0CI00
SMHPIIRKDASTSMT	ZNF705D	91	P0CH99
IRKDASTSMTMENSL	ZNF705D	96	P0CH99
TMVMEALSLAKSSSH	TASOR2	1156	Q5VWN6
MKLDLTMDSPSLSSS	TOGARAM1	1001	Q9Y4F4
MLASLMSSLTSIFNS	SLC5A1	386	P13866
MRLLSVFMSRTKSGS	UBR4	3056	Q5T4S7
LRATMQRKGISSSMS	TUB	181	P50607
LASSTMDSQMLATSS	SON	756	P18583
LATSSMDSQMLATSS	SON	766	P18583
LATSSMDSQMLATSS	SON	796	P18583
LATSSMDSQMLATSS	SON	806	P18583
LATSSMDSQMLATSS	SON	816	P18583
SLKSMMEFSSTRHSI	ZNF816	66	Q0VGE8