Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14 CTBP2 CNOT1

1.71e-05551986GO:0042974
GeneOntologyMolecularFunctionbiotin binding

ACACA ACACB PC

1.88e-0561983GO:0009374
GeneOntologyMolecularFunctionligase activity, forming carbon-carbon bonds

ACACA ACACB PC

3.26e-0571983GO:0016885
GeneOntologyMolecularFunctionacetyl-CoA carboxylase activity

ACACA ACACB

9.78e-0521982GO:0003989
GeneOntologyMolecularFunctionnuclear receptor binding

ISL1 PRAMEF1 PRAMEF2 JUP PRAMEF13 PRAMEF14 PRKCB CTBP2 CNOT1

1.07e-041871989GO:0016922
GeneOntologyMolecularFunctionapolipoprotein receptor activity

ABCA7 LRP1

2.92e-0431982GO:0030226
DomainBiotin_BS

ACACA ACACB PC

1.02e-0551903IPR001882
DomainBiotin_COase_C

ACACA ACACB PC

1.02e-0551903IPR005482
DomainBC

ACACA ACACB PC

1.02e-0551903PS50979
DomainBiotin_carb_C

ACACA ACACB PC

1.02e-0551903SM00878
DomainBiotin_carb_C

ACACA ACACB PC

1.02e-0551903PF02785
DomainBiotin_carboxylation_dom

ACACA ACACB PC

1.02e-0551903IPR011764
DomainBIOTIN

ACACA ACACB PC

1.02e-0551903PS00188
DomainRudment_hybrid_motif

ACACA ACACB PC

2.03e-0561903IPR011054
DomainCbamoylP_synth_lsu-like_ATP-bd

ACACA ACACB PC

3.52e-0571903IPR005479
DomainBC-like_N

ACACA ACACB PC

3.52e-0571903IPR005481
DomainCPSase_L_D2

ACACA ACACB PC

3.52e-0571903PF02786
DomainBiotin_carb_N

ACACA ACACB PC

3.52e-0571903PF00289
DomainBiotin_lipoyl

ACACA ACACB PC

8.32e-0591903PF00364
DomainACC_central

ACACA ACACB

1.03e-0421902PF08326
DomainAcCoA_COase_cen

ACACA ACACB

1.03e-0421902IPR013537
DomainLRDF

LEFTY2 LEFTY1

1.03e-0421902IPR003942
DomainBIOTINYL_LIPOYL

ACACA ACACB PC

1.18e-04101903PS50968
DomainBiotin_lipoyl

ACACA ACACB PC

1.18e-04101903IPR000089
DomainSingle_hybrid_motif

ACACA ACACB PC

2.13e-04121903IPR011053
Domain-

ACACA ACACB PC

2.75e-041319033.40.50.20
DomainATP_GRASP

ACACA ACACB PC

3.47e-04141903PS50975
DomainATP-grasp

ACACA ACACB PC

3.47e-04141903IPR011761
DomainPreATP-grasp_dom

ACACA ACACB PC

3.47e-04141903IPR016185
Domain-

ACACA ACACB PC

4.31e-041519033.30.1490.20
DomainCarboxyl_trans

ACACA ACACB

6.09e-0441902PF01039
DomainCOA_CT_CTER

ACACA ACACB

6.09e-0441902PS50989
DomainCOA_CT_NTER

ACACA ACACB

6.09e-0441902PS50980
DomainCOA_CT_N

ACACA ACACB

6.09e-0441902IPR011762
DomainCOA_CT_C

ACACA ACACB

6.09e-0441902IPR011763
DomainCarboxyl_trans

ACACA ACACB

6.09e-0441902IPR000022
DomainARM

JUP PKP1 GCN1 ODAD2

7.12e-04401904SM00185
DomainARM-type_fold

IFT172 FMNL2 JUP CLTC PKP1 GCN1 ODAD2 ELMO3 EIF5 AP4B1 SYMPK

7.28e-0433919011IPR016024
DomainATP_grasp_subdomain_1

ACACA ACACB PC

7.56e-04181903IPR013815
Domain-

ACACA ACACB PC

7.56e-041819033.30.470.20
DomainPRAME_family

PRAMEF1 PRAMEF2 PRAMEF13

8.91e-04191903IPR026271
DomainSortilin_C

SORT1 SORL1

1.01e-0351902PF15901
DomainSortilin-Vps10

SORT1 SORL1

1.01e-0351902PF15902
DomainVPS10

SORT1 SORL1

1.01e-0351902IPR006581
DomainSortilin_N

SORT1 SORL1

1.01e-0351902IPR031778
DomainSortilin_C

SORT1 SORL1

1.01e-0351902IPR031777
DomainVPS10

SORT1 SORL1

1.01e-0351902SM00602
DomainCPSASE_1

ACACA ACACB

1.01e-0351902PS00866
Domain-

ACACA ACACB ECHDC3

1.20e-032119033.90.226.10
DomainClpP/crotonase-like_dom

ACACA ACACB ECHDC3

1.20e-03211903IPR029045
DomainArmadillo

JUP PKP1 GCN1 ODAD2

1.32e-03471904IPR000225
DomainCPSASE_2

ACACA ACACB

1.50e-0361902PS00867
PathwayWP_FATTY_ACID_BIOSYNTHESIS

ACACA ACACB ECHDC3 PC

7.76e-05221504M39440
PathwayWP_FATTY_ACID_BIOSYNTHESIS

ACACA ACACB ECHDC3 PC

9.32e-05231504MM15885
PathwayWP_BIOTIN_METABOLISM_INCLUDING_IMDS

ACACA ACACB PC

9.46e-0591503M40064
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

VWA5B2 TANC2 ACACA PCNX3 UBE4B FYCO1 BIRC6 ABCA7 PTPRF GCN1 ZNF687 HSPG2 BICRA LAMA5 MLXIP MADD ARHGEF10L LLGL2 KANK3 PAXIP1 XXYLT1 PC CABIN1 ESPL1 SYMPK KLHL17

1.19e-0911051992635748872
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NR2C2 ACACA ACACB ZNF318 BIRC6 JUP MGA GCN1 ZNF687 ATG2B SFMBT2 LRP1 ANKRD17 CTBP2 PC CNOT1

3.00e-094181991634709266
Pubmed

Network organization of the human autophagy system.

ACACA FYCO1 NUP205 TGFBRAP1 CLTC PKP1 GCN1 VARS1 DSC1 NSF ATG2B MAP3K6 NUP155 EIF5 EIF3A TEDC1

5.62e-094371991620562859
Pubmed

Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.

PRAMEF1 PRAMEF2 PRAMEF13 LEFTY2 LEFTY1 PRAMEF14

6.81e-0926199618500982
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

ACACA TIGD4 STOX1 FMNL2 BIRC6 QRICH2 PCDH17 NUP205 TTLL12 FREM2 JUP TRPM3 CLTC SLC26A9 KCNG4 XXYLT1 PRKCB EIF3A CNOT1 SYMPK

1.06e-087361992029676528
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

ACACA ACACB ZNF318 JUP CLTC MGA GCN1 VARS1 ZNF687 DSC1 NUP155 PC ATP5F1B SYMPK

2.22e-083571991437059091
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

ACACA ME2 NUP205 BLMH JUP CLTC PKP1 GCN1 VARS1 RAD23A DSC1 NSF GPS1 MUC5B NUP155 SFXN3 EIF5 SMARCA2 LRP1 ANKRD17 AATF EIF3A PC CNOT1 TOP2A ATP5F1B SYMPK

2.23e-0813671992732687490
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

CCDC8 PABPC4 ZNF318 F5 NUP205 BLMH JUP PTPRF CLTC PKP1 MGA GCN1 VARS1 KIFC1 POLR1A NSF NUP155 AATF EIF3A CNOT1 TOP2A AQR ATP5F1B

2.72e-0810241992324711643
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

CCDC8 ACACA FYCO1 ZNF318 NUP205 CLTC ZNF687 POLR1A NUP155 SMARCA2 ANKRD17 AATF ESPL1 TOP2A AQR

4.37e-084401991534244565
Pubmed

Human transcription factor protein interaction networks.

NR2C2 CCDC8 ACACB PABPC4 NBN ZNF318 GMEB2 NUP205 JUP HOXD11 TAF4 MGA ZNF687 KIFC1 HSPG2 NEPRO BICRA PAXIP1 SMARCA2 ANKRD17 CTBP2 EIF3A CABIN1 CNOT1 SORL1 SYMPK RAVER1

5.52e-0814291992735140242
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ACACA UBE4B BIRC6 NUP205 BLMH JUP CLTC PKP1 MGA GCN1 VARS1 KRT2 POLR1A DSC1 ARHGAP23 POLR1D NUP155 SFXN3 SMARCA2 ANKRD17 AATF CTBP2 EIF3A TOP2A AQR ATP5F1B

7.16e-0813531992629467282
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

NR2C2 ACACA ACACB PABPC4 GMEB2 NUP205 CLTC TAF4 GCN1 VARS1 ZNF687 KRT2 POLR1A NSF GSK3A POLR1D SMARCA2 PRKCB AATF CTBP2 EIF3A PC TOP2A AQR ATP5F1B

1.67e-0713181992530463901
Pubmed

Endocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families.

SORT1 APOA5 SORL1

1.85e-073199318603531
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

ACACA PABPC4 ME2 NUP205 TTLL12 BLMH JUP CLTC PKP1 FGD5 GCN1 VARS1 KIFC1 POLR1A DSC1 NSF NUP155 SFXN3 EIF5 CTBP2 EIF3A PC CNOT1 TOP2A AQR ATP5F1B

1.96e-0714251992630948266
Pubmed

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.

SLC6A19 NUP205 TTLL12 JUP CLTC PKP1 GCN1 VARS1 KRT2 DSC1 NUP155 CTBP2 EIF3A PC CNOT1 TOP2A ATP5F1B

1.99e-076411991736057605
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

ACACA PABPC4 NBN HAUS3 SECISBP2 MGA GCN1 VARS1 POLR1A THOC6 POLR1D SFXN3 EIF5 ANKRD17 AATF ESPL1 CNOT1 RAVER1

2.23e-077241991836232890
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ACACA PABPC4 ZNF318 BIRC6 ME2 NUP205 TTLL12 CLTC GCN1 POLR1A NUP155 SMARCA2 ANKRD17 AATF CNOT1 AQR SYMPK

2.58e-076531991722586326
Pubmed

Functional proteomics mapping of a human signaling pathway.

HIPK1 PABPC4 FMNL2 CISH JUP PTPRF SECISBP2 MGA HSPG2 LAMA5 TDG PPARD NUP155 PAXIP1 LRP1 CTBP2

3.51e-075911991615231748
Pubmed

Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability.

ACACA ACACB PC

7.35e-074199338447582
Pubmed

The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain.

SORT1 LRP1 SORL1

7.35e-074199323283348
Pubmed

Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.

ACACA PABPC4 NUP205 TTLL12 CLTC GCN1 VARS1 KRT2 HSPG2 NUP155 EIF5 PRKCB EIF3A CNOT1 TOP2A ATP5F1B RAVER1

7.74e-077071991719738201
Pubmed

A human MAP kinase interactome.

HIPK1 FMNL2 JUP SIMC1 CLTC MGA GCN1 BICRA PLEKHA6 MADD DYRK1B ANKRD17 EIF3A MAP2K5

9.39e-074861991420936779
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

GLT1D1 FYCO1 ISL1 PRAMEF1 PRAMEF2 NUP205 SORT1 JUP PKP1 GCN1 KRT2 PRAMEF13 PRAMEF14 ANKRD17 ATP5F1B

1.03e-065641991521565611
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

TTLL12 FREM2 KIFC1 DMXL2 ARHGAP23 MAP3K6 MADD LLGL2 NUP155 ANKRD17 AP4B1 PLCH1 PATJ AQR SORL1 RAVER1

1.22e-066501991638777146
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

ACACA PRAMEF1 PRAMEF2 BIRC6 MGA HSPG2 FMO5 LAMA5 PRAMEF13 PRAMEF14 CABIN1 KLHL17

1.40e-063631991214691545
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

FTSJ1 NUP205 BLMH JUP PKP1 GCN1 VARS1 RAD23A NEPRO POLR1A DSC1 NSF GPS1 NUP155 SMARCA2 LRP1 ANKRD17 EIF3A CNOT1 AQR

1.52e-0610051992019615732
Pubmed

Defining the interactions between intermediate filaments and desmosomes.

JUP PKP1 DSC1

1.83e-06519939606214
Pubmed

Apolipoprotein A-V interaction with members of the low density lipoprotein receptor gene family.

APOA5 LRP1 SORL1

1.83e-065199317326667
Pubmed

The desmoglein-specific cytoplasmic region is intrinsically disordered in solution and interacts with multiple desmosomal protein partners.

JUP PKP1 DSC1

1.83e-065199319136012
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

NR2C2 ACACA NBN ZNF318 GMEB2 BLMH SIMC1 TAF4 MGA EIF5 PC TOP2A SYMPK

1.94e-064441991334795231
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

ZNF318 COL24A1 TRPM3 SKOR2 GPATCH11 PKP1 FGD5 TAF4 MGA RAD23A DMXL2 GPS1 ACAD10 MADD EIF5 SYMPK

2.59e-066891991636543142
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

NUP205 CLTC GCN1 CCDC157 KRT2 POLR1A EIF3A CNOT1 AQR

2.73e-06202199924639526
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

ACACA PABPC4 NBN BIRC6 NUP205 TTLL12 GCN1 VARS1 POLR1A NUP155 ANKRD17 CTBP2 EIF3A CNOT1

2.81e-065341991435032548
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

ACACA NRROS NUP205 CLTC TAF4 GCN1 VARS1 HSPG2 GPS1 LAMA5 NUP155 LRP1 EIF3A ATP5F1B SORL1

2.86e-066131991522268729
Pubmed

The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

2.99e-0618199423894331
Pubmed

Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

2.99e-0618199412890732
Pubmed

Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

2.99e-0618199429731491
Pubmed

Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

2.99e-0618199414675769
Pubmed

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.

HIPK1 NUP205 PTPRF SIMC1 GCN1 ZNF687 NSF EIF3A TOP2A SYMPK

3.04e-062621991036880596
Pubmed

Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

3.77e-0619199428604677
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ACACA NBN ZNF318 JUP CLTC TAF4 MGA GCN1 ATG2B PATJ PC CNOT1 TOP2A SYMPK

3.86e-065491991438280479
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

TANC2 PDE6A ACACB NBN NRROS GPATCH11 FGD5 FHIP2B ZNF687 PAXIP1 SMARCA2 ANKRD17 AATF CNOT1 RAVER1

4.63e-066381991531182584
Pubmed

Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

4.69e-0620199426694250
Pubmed

Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

4.69e-0620199416580637
Pubmed

Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

4.69e-0620199421425410
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NR2C2 PABPC4 ZNF318 GMEB2 TTLL12 BLMH CLTC TAF4 VARS1 ZNF687 KIFC1 RAD23A BICRA POLR1D EIF5 PAXIP1 SMARCA2 CNOT1 TOP2A RAVER1

6.08e-0611031992034189442
Pubmed

Association of blood lipids with common DNA sequence variants at 19 genetic loci in the multiethnic United States National Health and Nutrition Examination Survey III.

SORT1 PSRC1 APOA5

6.35e-067199320031591
Pubmed

Interaction network of human early embryonic transcription factors.

NR2C2 ACACB ME2 SORT1 TAF4 MGA BICRA PAXIP1 SMARCA2 CTBP2 TOP2A

6.42e-063511991138297188
Pubmed

Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

7.02e-0622199431729367
Pubmed

Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

8.46e-0623199419480014
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

UBE4B NUP205 SORT1 TTLL12 PTPRF CLTC GCN1 VARS1 POLR1A NSF GPS1 GSK3A NUP155 XXYLT1 ANKRD17 ESPL1 SYMPK RAVER1

9.01e-069421991831073040
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

TANC2 PABPC4 HAUS3 FYCO1 POLR3D PSRC1 ZC3H12A PLEKHA6 MLXIP VPS37B MADD PDE8B EIF5 PAXIP1 AATF AP4B1 ESPL1 CNOT1 TEDC1

9.21e-0610381991926673895
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

PDE6A ACACB FAM178B PABPC4 ZNF318 STOX1 NUP205 CLTC TAF4 VARS1 KRT2 PCDHGA10 GPS1 SFMBT2 CAPN11 THOC6 RGS14 AATF EIF3A PLCH1 TUBD1 TOP2A ATP5F1B

9.65e-0614421992335575683
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TANC2 CCDC8 ACACA TTLL12 JUP MLXIP MAP3K6 GSK3A MADD DYRK1B EIF5 ANKRD17 PLCH1 PATJ PC AQR CDK3

1.06e-058611991736931259
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

NR2C2 PABPC4 NBN ZNF318 JUP SIMC1 CLTC TAF4 MGA KIFC1 BICRA POU4F3 EIF5 AATF PC TOP2A ATP5F1B SYMPK

1.07e-059541991836373674
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

ACACA PABPC4 JUP CLTC MGA GCN1 VARS1 ANKRD35 NSF PLEKHA6 GSK3A THOC6 SMARCA2 ANKRD17 CTBP2 PATJ TOP2A AQR CDK3 ATP5F1B RAVER1

1.08e-0512471992127684187
Pubmed

Characterization of staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1.

PABPC4 CLTC GCN1 VARS1 NSF NUP155 EIF3A ATP5F1B RAVER1

1.14e-05241199923125841
Pubmed

Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

1.20e-0525199412620990
Pubmed

MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

1.20e-0525199437451217
Pubmed

Dystroglycan Maintains Inner Limiting Membrane Integrity to Coordinate Retinal Development.

ISL1 HSPG2 PRKCB CTBP2

1.20e-0525199428760865
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

PABPC4 FTSJ1 F5 NUP205 JUP CLTC PKP1 KIFC1 KRT2 DSC1 THOC6 NUP155 EIF5 ANKRD17 AATF EIF3A PATJ TOP2A AQR ATP5F1B RAVER1

1.22e-0512571992136526897
Pubmed

TRIM25 and DEAD-Box RNA Helicase DDX3X Cooperate to Regulate RIG-I-Mediated Antiviral Immunity.

PABPC4 BLMH JUP PKP1 KRT2 DSC1

1.45e-0591199634445801
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

ACACA UBE4B BIRC6 NUP205 CLTC GCN1 POLR1A GPS1 THOC6 EIF5 SMARCA2 ANKRD17 PC CNOT1 TOP2A

1.48e-057041991529955894
Pubmed

Coordinate Nodal and BMP inhibition directs Baf60c-dependent cardiomyocyte commitment.

ISL1 LEFTY2 LEFTY1

1.51e-059199324186978
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

ZNF318 PRAMEF1 PRAMEF2 ME2 JUP POLR3D CCNL1 CLTC MGA FHIP2B PRAMEF13 MADD PRAMEF14 SFXN3 ANKRD17 AATF PATJ ESPL1 CNOT1

1.68e-0510841991911544199
Pubmed

Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

1.91e-0528199425089626
Pubmed

Interactome of the Autoimmune Risk Protein ANKRD55.

ACACA NUP205 CLTC GCN1 VARS1 EIF3A CNOT1 ATP5F1B

1.93e-05197199831620119
Pubmed

A protein interaction landscape of breast cancer.

PABPC4 JUP CLTC PKP1 RAD23A DSC1 NSF BICRA GPS1 MUC5B THOC6 SMARCA2 LRP1 TOP2A

1.94e-056341991434591612
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

ACACA IFT172 NUP205 TTLL12 CLTC GCN1 VARS1 NSF GPS1 NUP155 EIF3A CNOT1 ATP5F1B SYMPK

2.08e-056381991433239621
Pubmed

HoxD cluster scanning deletions identify multiple defects leading to paralysis in the mouse mutant Ironside.

ISL1 HOXD10 HOXD11

2.15e-0510199316322559
Pubmed

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.

PABPC4 FYCO1 BLMH JUP CLTC PKP1 MGA VARS1 KRT2 DSC1 SFXN3 EIF3A ATP5F1B

2.23e-055581991327591049
Pubmed

The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.

ACACA PABPC4 TTLL12 GCN1 KRT2 EIF5 EIF3A PC TOP2A ATP5F1B

2.27e-053301991032529326
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

GCN1 HSPG2 SMARCA2 ANKRD17 CTBP2 CNOT1 CDK3 SYMPK

2.40e-05203199822083510
Pubmed

Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function.

GRIN2A LEFTY2 LEFTY1 ASPA

2.54e-0530199427568567
Pubmed

Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

2.54e-0530199438786026
Pubmed

Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta -catenin signaling.

JUP PKP1 DSC1

2.94e-0511199311790773
Pubmed

Hippi is essential for node cilia assembly and Sonic hedgehog signaling.

ISL1 LEFTY2 LEFTY1

2.94e-0511199317027958
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TANC2 FMNL2 BIRC6 TRPM3 ARHGAP25 MGA DMXL2 LRRN1 ARHGAP23 PLEKHA6 EIF3A PLCH1

3.03e-054931991215368895
Pubmed

A novel dominant mutation in plakoglobin causes arrhythmogenic right ventricular cardiomyopathy.

JUP HRC

3.26e-052199217924338
Pubmed

The active contribution of OPCs to neuroinflammation is mediated by LRP1.

OLIG1 LRP1

3.26e-052199231552482
Pubmed

LEFTY2 alleviates hepatic stellate cell activation and liver fibrosis by regulating the TGF-β1/Smad3 pathway.

LEFTY2 LEFTY1

3.26e-052199232745796
Pubmed

Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation.

ACACA ACACB

3.26e-052199224944901
Pubmed

AATF and SMARCA2 are associated with thyroid volume in Hashimoto's thyroiditis patients.

SMARCA2 AATF

3.26e-052199232019955
Pubmed

TR4 promotes fatty acid synthesis in 3T3-L1 adipocytes by activation of pyruvate carboxylase expression.

NR2C2 PC

3.26e-052199225240193
Pubmed

Hormonal regulation of acetyl-CoA carboxylase isoenzyme gene transcription.

ACACA ACACB

3.26e-052199220139635
Pubmed

LEFTY, a member of the transforming growth factor-beta superfamily, inhibits uterine stromal cell differentiation: a novel autocrine role.

LEFTY2 LEFTY1

3.26e-052199220056823
Pubmed

Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development.

LEFTY2 LEFTY1

3.26e-052199210053005
Pubmed

Inhibition of Acetyl-CoA Carboxylase 1 (ACC1) and 2 (ACC2) Reduces Proliferation and De Novo Lipogenesis of EGFRvIII Human Glioblastoma Cells.

ACACA ACACB

3.26e-052199228081256
Pubmed

Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats.

ACACA ACACB

3.26e-052199226976583
Pubmed

Mutation analysis of human LEFTY A and LEFTY B genes in children with Ivemark syndrome.

LEFTY2 LEFTY1

3.26e-052199211100524
Pubmed

Lefty1 and lefty2 control the balance between self-renewal and pluripotent differentiation of mouse embryonic stem cells.

LEFTY2 LEFTY1

3.26e-052199224147624
Pubmed

AMPK-dependent inhibitory phosphorylation of ACC is not essential for maintaining myocardial fatty acid oxidation.

ACACA ACACB

3.26e-052199225001074
Pubmed

The subcellular localization of acetyl-CoA carboxylase 2.

ACACA ACACB

3.26e-052199210677481
Pubmed

Susceptibility of podocytes to palmitic acid is regulated by fatty acid oxidation and inversely depends on acetyl-CoA carboxylases 1 and 2.

ACACA ACACB

3.26e-052199224338821
Pubmed

Lefty antagonises TGF-beta1 induced epithelial-mesenchymal transition in tubular epithelial cells.

LEFTY2 LEFTY1

3.26e-052199220171171
Pubmed

De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.

ACACA ACACB

3.26e-052199225282359
Pubmed

Stra3/lefty, a retinoic acid-inducible novel member of the transforming growth factor-beta superfamily.

LEFTY2 LEFTY1

3.26e-05219929496783
Pubmed

Acetyl-CoA carboxylase rewires cancer metabolism to allow cancer cells to survive inhibition of the Warburg effect by cetuximab.

ACACA ACACB

3.26e-052199227693630
Pubmed

A functional role of LEFTY during progesterone therapy for endometrial carcinoma.

LEFTY2 LEFTY1

3.26e-052199229268772
Pubmed

Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue.

ACACA ACACB

3.26e-052199232215608
InteractionKDM1A interactions

NR2C2 ACACA ACACB HAUS3 FYCO1 ZNF318 ISL1 BIRC6 JUP MGA GCN1 VARS1 ZNF687 ATG2B PPARD VPS37B SFMBT2 LLGL2 SMARCA2 LRP1 ANKRD17 CTBP2 PC CNOT1 SYMPK

3.85e-0694119325int:KDM1A
InteractionPTPRN2 interactions

CCDC8 NUP205 SORT1 PTPRF GCN1 NUP155 LRP1

6.33e-06731937int:PTPRN2
InteractionSLX4 interactions

ACACA ACACB NBN ZNF318 JUP CLTC MGA GCN1 VARS1 ZNF687 DSC1 GSK3A NUP155 PAXIP1 AATF PC ATP5F1B SYMPK

1.05e-0557219318int:SLX4
InteractionFOXI2 interactions

NUP205 PKP1 VARS1 CTBP2 SORL1 SYMPK

1.13e-05531936int:FOXI2
InteractionCCDC8 interactions

CCDC8 PABPC4 ZNF318 F5 NUP205 BLMH JUP CLTC PKP1 GCN1 VARS1 KIFC1 POLR1A NSF NUP155 EIF3A CNOT1 TOP2A ATP5F1B

1.88e-0565619319int:CCDC8
InteractionSIRT6 interactions

CCDC8 ACACA FTSJ1 FYCO1 ZNF318 NUP205 CLTC ZNF687 POLR1A TDG NUP155 SMARCA2 ANKRD17 AATF ESPL1 TOP2A AQR SYMPK

3.61e-0562819318int:SIRT6
InteractionRNF123 interactions

ACACA TIGD4 STOX1 FMNL2 BIRC6 QRICH2 PCDH17 NUP205 TTLL12 FREM2 JUP TRPM3 CLTC SLC26A9 MAP3K6 KCNG4 XXYLT1 PRKCB EIF3A CNOT1 SYMPK

4.45e-0582419321int:RNF123
Cytoband1p36.21

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

1.64e-046319841p36.21
CytobandEnsembl 112 genes in cytogenetic band chr1p36

UBE4B PRAMEF1 PRAMEF2 DRAXIN CCNL2 HSPG2 PRAMEF13 MAP3K6 ARHGEF10L PRAMEF14 KLHL17

2.01e-0468119811chr1p36
Cytoband17q25.1

QRICH2 NT5C LLGL2 CDK3

4.31e-0481198417q25.1
GeneFamilyPRAME family

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

2.65e-05241334686
CoexpressionGSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_DN

FYCO1 ZNF318 CISH MGA OPLAH CCNL2 PLEKHA6 SNX29 EIF5 KLHL17

2.61e-0619919510M3583
CoexpressionGSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_UP

SLC6A19 POLR3D MGA POLR1A BICRA SNX29 ELMO3 EIF5 PATJ

5.72e-061711959M2947
ToppCellControl-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

TANC2 HIPK1 ZNF318 MGA PSRC1 DMXL2 MLXIP AQR TEDC1

1.39e-071841979ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCellfacs-MAT-Fat-3m-Endothelial-endothelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 C16orf89 JUP FGD5 VWA3A LAMA5 TIE1 KANK3

2.42e-061931978e164f6403a8b541ced08a6feec915d2e855036ea
ToppCellfacs-MAT-Fat-3m-Endothelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 C16orf89 JUP FGD5 VWA3A LAMA5 TIE1 KANK3

2.42e-061931978b32533afeff1905e188becaa09079e9699722e4b
ToppCellfacs-MAT-Fat-3m-Endothelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 C16orf89 JUP FGD5 VWA3A LAMA5 TIE1 KANK3

2.42e-0619319782ff573ba2c74583ed1cb071a3bbc01bb71117e5f
ToppCellPBMC-Mild-cDC_0|Mild / Compartment, Disease Groups and Clusters

GLT1D1 F5 SORT1 OLIG1 DMXL2 VPS37B LRP1 SORL1

2.93e-061981978fb873b7636bb1c7b119dd5b23d7a20f518e6c6da
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PDE6A JUP ASB9 HRC FGD5 HSPG2 TIE1 KANK3

3.04e-0619919781295f34a350bf48987e2fad411aaac3630efd3f1
ToppCellsevere-CD163+_Monocytes_(Sample_ID1_d7)|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RASGRP4 GLT1D1 ARL11 F5 SORT1 JUP DMXL2 LRP1

3.15e-0620019784943fe826d5fcc3dfeb8b99a7415848f3fecc994
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASGRP4 ARL11 F5 SEMA4A OLIG1 PGLYRP1 FCGR2C

1.18e-051721977cf46810dd1072b6f2171e5d9530351ddc79a055b
ToppCellE12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NRROS ARHGAP25 OPLAH HSPG2 POLR1A GSK3A XXYLT1

1.18e-0517219773b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Myeloid-new-cluster|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPN KIFC1 PGLYRP1 COMMD5 SLC26A9 ELMO3 TOP2A

1.27e-051741977718e14d9a4264456459bec4c062c94c3a848d43a
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 VWA3A HSPG2 APOA5 MAP3K6 TIE1 KANK3

1.37e-051761977eb63eb2c301e785196ccadac74a2940b2c524c62
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLRT1 SEMA4A GCN1 KIFC1 DMXL2 PPARD TOP2A

1.42e-0517719771d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCellmetastatic_Brain-B_lymphocytes-GrB-secreting_B_cells|B_lymphocytes / Location, Cell class and cell subclass

SPN GLT1D1 STOX1 TTLL12 COL24A1 DMXL2 IQCN

1.42e-05177197743e1d0d3cf8f0c02e67d91f8dd1761df23d59e07
ToppCellLPS-IL1RA-Myeloid-Neutrophils-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NBN CISH SEMA4A DMXL2 RILPL2 PGLYRP1 PRKCB

1.58e-051801977c0c07937839652e01df10cc1e70aa005800ea6f6
ToppCellLPS-IL1RA-Myeloid-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NBN CISH SEMA4A DMXL2 RILPL2 PGLYRP1 PRKCB

1.58e-051801977079c199425dd3c220f03c6dca1823946f07580a1
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac|lymph-node_spleen / Manually curated celltypes from each tissue

PSRC1 OPLAH KIFC1 DMXL2 ARHGEF10L ESPL1 TOP2A

1.58e-0518019774eea8366cdb82c356325ce88f09ad8b302c17a07
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASGRP4 SPN NRROS TBC1D10C ARHGAP25 OLIG1 PRKCB

1.58e-0518019771c5515f29ead129bee3b4ca27799796956811a39
ToppCellfacs-Heart-LV-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRROS SECISBP2 ARHGAP25 ZNF687 PPARD RGS14 PRKCB

1.64e-05181197757f82f54e20e19aa17a2ea22af22e3bc8965d622
ToppCellfacs-Heart-LV-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRROS SECISBP2 ARHGAP25 ZNF687 PPARD RGS14 PRKCB

1.64e-0518119778855812c85ef45c1be6bd511619b2dfe5e441264
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JPH4 PCDH17 ASB9 FGD5 HSPG2 TIE1 KANK3

1.70e-0518219773cbeaf7904a76c32137a00abb20e302d3d3c8bb8
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 VWA3A HSPG2 APOA5 MAP3K6 TIE1 KANK3

1.70e-051821977ab5761bf9af439231cd0f487b6467e372672a517
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F5 SLC26A1 PTPRF SLC38A3 ACAD10 VWCE PC

1.70e-05182197777ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F5 SLC26A1 PTPRF SLC38A3 ACAD10 VWCE PC

1.70e-0518219774921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F5 SLC26A1 PTPRF SLC38A3 ACAD10 VWCE PC

1.70e-051821977770ce9f3f4538d0181a0181543841bc964c68274
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 VWA3A HSPG2 APOA5 MAP3K6 TIE1 KANK3

1.70e-0518219773b4dbf61ca0fe50efe05449815630e301cb76630
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TANC2 GLT1D1 HIPK1 PSRC1 DMXL2 TOP2A TEDC1

1.82e-051841977081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL24A1 FREM2 TRPM3 NRK MUC5B ODAD2 PLCH1

1.82e-0518419772cbed6462fea2622871bb7e49b0df3d984239281
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TANC2 GLT1D1 HIPK1 PSRC1 DMXL2 TOP2A TEDC1

1.82e-05184197784c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TANC2 GLT1D1 HIPK1 PSRC1 DMXL2 TOP2A TEDC1

1.82e-051841977d31d4116d1d196633784863781fa45673607a421
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL24A1 FREM2 TRPM3 NRK MUC5B ODAD2 PLCH1

1.82e-0518419772b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TANC2 GLT1D1 HIPK1 PSRC1 DMXL2 TOP2A TEDC1

1.82e-051841977a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

TANC2 GLT1D1 HIPK1 PSRC1 DMXL2 TOP2A TEDC1

1.82e-05184197745f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL24A1 FREM2 TRPM3 NRK MUC5B ODAD2 PLCH1

1.82e-051841977ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ASB9 FGD5 HSPG2 POU4F3 TIE1 KCNG4 KANK3

1.89e-0518519770ab1be455f2cd883c9d1522ca78112c37833352e
ToppCell356C-Endothelial_cells-Endothelial-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

QRICH2 PCDH17 PKP1 HSPG2 ARHGAP23 CAPN11 TIE1

1.95e-0518619772e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell356C-Endothelial_cells-Endothelial-E|356C / Donor, Lineage, Cell class and subclass (all cells)

QRICH2 PCDH17 PKP1 HSPG2 ARHGAP23 CAPN11 TIE1

1.95e-051861977c3449e54454009973818fc1101933c6f0168258c
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 C16orf89 FGD5 HSPG2 ARHGAP23 PCDHGA10 TIE1

2.09e-0518819770aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASGRP4 SPN NRROS TBC1D10C ARHGAP25 OLIG1 PRKCB

2.09e-051881977ab95a97db1a84bf3e53a4616a83ee81a6ce5ec12
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 C16orf89 FGD5 HSPG2 ARHGAP23 PCDHGA10 TIE1

2.24e-051901977a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 C16orf89 FGD5 HSPG2 ARHGAP23 PCDHGA10 TIE1

2.24e-05190197725525fee1da8a808034d9c916159fd0b6b26bce8
ToppCellfacs-SCAT-Fat-3m-Endothelial-endothelial_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 JUP FGD5 VWA3A LAMA5 TIE1 KANK3

2.31e-0519119776b9bbf4a63d4e9a8075bb06c2aa644fcf4ee88b8
ToppCellfacs-SCAT-Fat-3m-Endothelial-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 JUP FGD5 VWA3A LAMA5 TIE1 KANK3

2.31e-051911977a0018f88f7132477cc467ee15db029a585290595
ToppCellfacs-SCAT-Fat-3m-Endothelial|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 JUP FGD5 VWA3A LAMA5 TIE1 KANK3

2.31e-05191197790f0c193dce267a4f1a9b2501f636dafd0a34cf7
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CISH TRPM3 LRRN1 MADD PAXIP1 PRKCB PC

2.39e-0519219775b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 C16orf89 HOXD10 FGD5 HSPG2 ARHGAP23 TIE1

2.47e-051931977826b8dd801298b3e0cd76232feae5a14026b8806
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TANC2 FMNL2 BIRC6 PLEKHA6 PPARD SNX29 ANKRD17

2.47e-051931977779276e775cb2492e8dd36436295a536084a6415
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 C16orf89 HOXD10 FGD5 HSPG2 ARHGAP23 TIE1

2.47e-05193197787d3a577d37fb0cb4b6313c596310de452bc3872
ToppCelldroplet-Bladder-BLADDER-1m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 C16orf89 FREM2 HRC FGD5 TIE1 KANK3

2.47e-05193197713731b7fc1e3bec0cebc44bad7e2ecea358bb76a
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TANC2 ACACA C16orf89 FREM2 FMO5 SLC26A9 PLCH1

2.47e-051931977f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASGRP4 GLT1D1 SEMA4A OLIG1 RILPL2 PGLYRP1 FCGR2C

2.47e-051931977c0509798ce06da0ec725c0c7b5cc195455f2c29f
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TANC2 ACACA C16orf89 FREM2 FMO5 SLC26A9 PLCH1

2.47e-051931977fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCelldroplet-Bladder-BLADDER-1m-Endothelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 C16orf89 FREM2 HRC FGD5 TIE1 KANK3

2.47e-0519319773a5090f81f35026f435f4a250d1e77601a53af15
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISL1 CISH PTPRF CLTC MADD PRKCB PC

2.47e-051931977471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISL1 CISH PTPRF CLTC MADD PRKCB PC

2.47e-051931977fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCellfacs-Kidney-nan-3m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 C16orf89 JUP FGD5 HSPG2 TIE1 KANK3

2.56e-0519419775fa2dfca32cca4abfda0af90b83f2b2a826f9b6e
ToppCellfacs-Kidney-nan-3m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 C16orf89 JUP FGD5 HSPG2 TIE1 KANK3

2.56e-05194197704df35246287815bdd28adaf885bdb98cf49524e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TANC2 ACACA FREM2 FMO5 SLC26A9 PLCH1 PATJ

2.56e-05194197797534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellfacs-Kidney-nan-3m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 C16orf89 JUP FGD5 HSPG2 TIE1 KANK3

2.56e-05194197790928d6c96c6304ae35dcc0275f7889de93da100
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SPN F5 C16orf89 FREM2 PGLYRP1 TIE1

2.59e-051311976d5bc40cd585582856881081b7130dec3515b4ae0
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 FGD5 FLRT1 HSPG2 ARHGAP23 TIE1 KANK3

2.64e-051951977126f46dd15dddcf5701144718bb8ba1ce84b2d1d
ToppCellwk_15-18-Epithelial-Distal_epithelial-type_II_pneumocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

C16orf89 FREM2 PTPRF HSPG2 LAMA5 LLGL2 PATJ

2.64e-0519519770e3aac1b1a1fd483f5fb9a394eb90c0e1ce63542
ToppCellfacs-GAT-Fat-3m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 JUP FGD5 VWA3A LAMA5 TIE1 KANK3

2.73e-051961977b6cc1f466d45479764080d34b1daeb8243a5a9f3
ToppCellfacs-GAT-Fat-3m-Endothelial-endothelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 JUP FGD5 VWA3A LAMA5 TIE1 KANK3

2.73e-051961977ede6104cdfa4ee5287efcca9bbc36677cbf7a8d8
ToppCellfacs-GAT-Fat-3m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH17 JUP FGD5 VWA3A LAMA5 TIE1 KANK3

2.73e-051961977039044ab28c53391c34d8226fb8cf78549e63ef4
ToppCellAT1-AT2_cells|World / lung cells shred on cell class, cell subclass, sample id

ABCA7 JUP PTPRF HSPG2 LAMA5 LLGL2 PATJ

2.91e-051981977a5b3617ea2ed4bffba59edcf6284799c2b3bbb29
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCDH17 FGD5 KIFC1 HSPG2 TIE1 KANK3 TOP2A

2.91e-051981977604fb20ca1aaf8f07067a8e1593a30ba335891f7
ToppCellmLN-T_cell-cycling_gd_T|T_cell / Region, Cell class and subclass

SORT1 PSRC1 KIFC1 TIE1 CTBP2 ESPL1 TOP2A

3.01e-051991977c81a194f8c2f120c6c4d74857912865a3c2fe1e7
ToppCellPBMC-Control-cDC_0|Control / Compartment, Disease Groups and Clusters

GLT1D1 F5 DMXL2 VPS37B ARHGEF10L LRP1 SORL1

3.01e-051991977ebf03979ef56e978d72db475bb635b43b9cbe402
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-MyoFB-3|PND01-03-samps / Age Group, Lineage, Cell class and subclass

QRICH2 WNT5B COL24A1 POLR3D SLC38A3 POU4F3

3.07e-0513519765b13ff740d9f7d96274aebb6b389a80f6004adc7
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NBN SEMA4A DMXL2 RILPL2 PGLYRP1 FCGR2C SORL1

3.11e-052001977fd1b6db3c62f5a205b769ba0e61433dae6285b67
ToppCellcontrol-HLA-DR-_S100A+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RASGRP4 ARL11 F5 SEMA4A OLIG1 ARHGEF10L LRP1

3.11e-052001977107a0665fb20247511a430178effd7630a619488
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Granulocytic_cells|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NBN SEMA4A DMXL2 RILPL2 PGLYRP1 FCGR2C SORL1

3.11e-0520019770b7573ec4e9c67c7d11dd8f5011a70bade30e930
ToppCell356C-Lymphocytic-NK_cells-NK_cell_A2|356C / Donor, Lineage, Cell class and subclass (all cells)

FAM178B SFMBT2 TIE1 ESPL1 TOP2A KLHL17

5.53e-0515019766bdf9df586f348641a25a445e83a41e47e7f347e
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPN F5 TBC1D10C SEMA4A PGLYRP1 RGS14

6.64e-051551976c648512305166d2a2f0e284c127bc802af908071
ToppCellBAL-Severe-cDC_4|Severe / Compartment, Disease Groups and Clusters

RASGRP4 NR2C2 ACACB IFT172 F5 FMO5

7.38e-05158197673f66689ef59f71b14cb7141ca5951cc47fe57c1
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 FREM2 FHIP2B PGLYRP1 ARHGEF10L LRP1

7.38e-051581976b0508a600994090c6aafd8d779437190a33ad821
ToppCellfacs-Lung-EPCAM-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 FREM2 FHIP2B PGLYRP1 ARHGEF10L LRP1

7.38e-051581976a816cc095452308d06f87b77467e2a8c6361fd2a
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Myeloid-cardiac_mast_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 F5 ZC3H12A PGLYRP1 RGS14 SORL1

7.64e-051591976766dfb9f9c0783e740a4fd395e99669310b33371
ToppCell3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IFT172 STOX1 PKP1 KRT2 LRRN1 MUC5B

7.91e-0516019766005948e400e781cdb876ba350b3ec8991e3945f
ToppCellfacs-Lung-Endomucin-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PABPC4 TBC1D10C VPS37B SFMBT2 MADD RGS14

7.91e-0516019760fee84844733d36805e1df90ca09478169746708
ToppCellfacs-Lung-Endomucin-3m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PABPC4 TBC1D10C VPS37B SFMBT2 MADD RGS14

7.91e-0516019765c68d6a76c59e3a7e668ae5471396478a55756ac
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 F5 ABCA7 DMXL2 PGLYRP1 SORL1

8.19e-051611976e227f7b711475624cf80e77f235b1783d88d57b4
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 F5 ABCA7 DMXL2 PGLYRP1 SORL1

8.19e-0516119768280a029026c272cae9649b27575831b0dd4e242
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

HIPK1 FYCO1 MGA SFMBT2 ARHGEF10L SORL1

8.47e-051621976810881210e015c788814e4fe8d7a24c929cf2621
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

STOX1 QRICH2 CCDC157 FMO5 LRP1 TOP2A

8.76e-051631976360cd65decda24853124f33a174f5224d7f3ce23
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

STOX1 QRICH2 CCDC157 FMO5 LRP1 TOP2A

8.76e-051631976b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PCDH17 FGD5 HSPG2 ARHGAP23 TIE1 KANK3

8.76e-05163197673c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-B_cells-CLP|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPN NRROS TBC1D10C COL24A1 ARHGAP25 PRKCB

9.06e-051641976f5cacd7b2329cb0c7c1696eb4d8f89a4bbd9dda1
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

NR2C2 IFT172 HIPK1 PTPRF MGA ACAD10

9.69e-05166197632d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCelldroplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 F5 SEMA4A OPLAH ACAD10 SORL1

9.69e-051661976de319c960b0cd90b294f677d1ea1b013a2ce2d53
ToppCelldroplet-Heart-nan-24m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GMEB2 KIFC1 BICRA MADD ECHDC3 TOP2A

1.00e-041671976bad33497ceeab968a7eb8a48b921c6f936390743
ToppCellClub-club-11|World / Class top

PDE6A C16orf89 PGLYRP1 MUC5B

1.02e-04551974d1d832e1c98a89e2b461127922c3e4d7f42d7401
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACACA PTPRF SLC38A3 FMO5 APOA5 PC

1.03e-041681976b98af4043dfa5dfa4413e482879fad88de484675
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 SPN PGLYRP1 ARHGEF10L LRP1 PRKCB

1.03e-041681976c0aef5947b1d7e2c81a7481c509feda1687fcd7f
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 SPN PGLYRP1 ARHGEF10L LRP1 PRKCB

1.03e-041681976c861f80aa12caf54a94d93e38539ff41dc5227a6
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACACA PTPRF SLC38A3 FMO5 APOA5 PC

1.03e-041681976073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIGD4 ZNF318 TBC1D10C TYRP1 SNX29 PRKCB

1.10e-0417019767a4ed69c807c3761210776e8fe6680d1bd892e82
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 F5 DMXL2 FMO5 PGLYRP1 SORL1

1.14e-041711976ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 F5 DMXL2 FMO5 PGLYRP1 SORL1

1.14e-04171197697ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Col27a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ARHGAP25 SEMA4A ANKRD35 RGS14 LLGL2 KCNG4

1.14e-041711976d07e2c5f7d7f12c68860d4161d76372de174f1d8
DrugDihydroergotamine tartrate [5989-77-5]; Down 200; 3uM; PC3; HT_HG-U133A

UBE4B SPN ZNF318 NT5C ARL14 ZC3H12A FMO5 PPARD MADD PC TUBD1

9.64e-07192197112081_DN
DrugNifurtimox [23256-30-6]; Down 200; 14uM; PC3; HT_HG-U133A

SPN SCN10A ZC3H12A ACAD10 RGS14 LRP1 PATJ PC CABIN1 MAP2K5 AQR

1.31e-06198197116608_DN
Drug3-methylcrotonylglycine

ACACA NBN ACAD10 PC

6.89e-06151974CID000169485
DrugIsoxsuprine hydrochloride [579-56-6]; Up 200; 11.8uM; PC3; HG-U133A

SPN PTPRF SEMA4A ARL14 KRT2 BICRA PLEKHA6 MADD SMARCA2 PC

8.49e-06196197101904_UP
DiseaseNicolaides Baraitser syndrome

NBN SMARCA2

3.95e-0521862C1303073
DiseaseAlzheimer disease, educational attainment

ABCA7 PCDH17 PTPRF SKOR2 SNX29 ECHDC3 SMARCA2 SORL1

1.83e-042471868EFO_0011015, MONDO_0004975
Diseasesortilin measurement

SORT1 PSRC1

2.35e-0441862EFO_0600000
Diseasemuscular disease (implicated_via_orthology)

ACACA ACACB

3.90e-0451862DOID:0080000 (implicated_via_orthology)
DiseaseAdenoid Cystic Carcinoma

WNT5B MGA SMARCA2 ESPL1 TOP2A

4.38e-041001865C0010606
DiseaseManic Disorder

ME2 GRIN2A GSK3A PC

1.07e-03711864C0024713
Diseasechildhood trauma measurement, alcohol consumption measurement

TANC2 PCDHGA10 SFMBT2 POLR1D

1.07e-03711864EFO_0007878, EFO_0007979
Diseaseholoprosencephaly (is_implicated_in)

PLCH1 CNOT1

1.08e-0381862DOID:4621 (is_implicated_in)
Diseaseamino acid measurement

TANC2 ACACB CYP2J2 TIGD4 C16orf89 WNT5B COL24A1 LRRN1 ODAD2 MLXIP ECHDC3 AP4B1

1.30e-0367818612EFO_0005134
DiseaseOsteitis Deformans

NUP205 ZNF687

1.38e-0391862C0029401
DiseaseManic

ME2 GRIN2A GSK3A PC

1.52e-03781864C0338831
Diseasecystic kidney disease (implicated_via_orthology)

IFT172 LAMA5

1.72e-03101862DOID:2975 (implicated_via_orthology)
Diseaseuric acid measurement

PCNX3 ZNF318 BIRC6 F5 QRICH2 SIMC1 FLRT1 POLR1A ACAD10 PLEKHA6 MLXIP

1.78e-0361018611EFO_0004761
DiseaseCardiomegaly

HRC PPARD PRKCB CABIN1

1.82e-03821864C0018800
DiseaseCardiac Hypertrophy

HRC PPARD PRKCB CABIN1

1.82e-03821864C1383860
Diseaseaspirin use measurement

PCNX3 PSRC1 ACAD10

1.91e-03391863EFO_0007013
Diseasecolonic neoplasm

TIGD4 BICRA SYMPK

2.20e-03411863EFO_0004288
Diseaseobesity (implicated_via_orthology)

JUP HSD17B3 CRH CAPN11 POLR1D ATP5F1B

2.50e-032151866DOID:9970 (implicated_via_orthology)
Diseasedaytime rest measurement

ACACA TRPM3 SKOR2 GRIN2A PRKCB PATJ LINC01556

2.77e-032951867EFO_0007828
DiseaseMalignant neoplasm of salivary gland

WNT5B ESPL1 TOP2A

2.88e-03451863C0220636
Diseaseapolipoprotein A 1 measurement

ACACB PABPC4 NUP205 MGA APOA5 PPARD MLXIP MADD LRP1 CTBP2 CCDC17 CNOT1 SORL1

2.93e-0384818613EFO_0004614
DiseaseParoxysmal atrial fibrillation

UBE4B SCN10A HSPG2 XXYLT1 SORL1

3.16e-031561865C0235480
Diseasefamilial atrial fibrillation

UBE4B SCN10A HSPG2 XXYLT1 SORL1

3.16e-031561865C3468561
DiseasePersistent atrial fibrillation

UBE4B SCN10A HSPG2 XXYLT1 SORL1

3.16e-031561865C2585653
DiseaseSalivary Gland Neoplasms

WNT5B ESPL1 TOP2A

3.26e-03471863C0036095
Diseasecystic fibrosis associated meconium ileus

SLC26A9 PRSS58

3.42e-03141862EFO_0004608
Diseaseesterified cholesterol measurement, low density lipoprotein cholesterol measurement

PSRC1 ANKRD17

3.42e-03141862EFO_0004611, EFO_0008589
DiseaseAtrial Fibrillation

UBE4B SCN10A HSPG2 XXYLT1 SORL1

3.52e-031601865C0004238
Diseasemyocardial infarction (is_implicated_in)

CYP2J2 ISL1 F5 LRP1

3.61e-03991864DOID:5844 (is_implicated_in)
DiseaseBody Weight

HRC MAP2K5

3.93e-03151862C0005910
DiseaseDisease Exacerbation

ABCA7 PTPRF RAD23A TOP2A SYMPK

4.01e-031651865C0235874
DiseaseBell's palsy

MGA SLC38A3 POU4F3 PATJ

4.02e-031021864EFO_0007167
Diseasediacylglycerol 44:7 measurement

IFT172 APOA5

4.47e-03161862EFO_0020069
Diseasethyroid volume

SMARCA2 AATF

4.47e-03161862EFO_0004865
Diseaseurate measurement

PCNX3 ZNF318 BIRC6 QRICH2 PTPRF TGFBRAP1 FLRT1 VARS1 MLXIP RGS14 LRP1 PC CCDC17

4.60e-0389518613EFO_0004531
Diseasecortical thickness

VWA5B2 FAM178B ZNF318 STOX1 FMNL2 ME2 PCDH17 PTPRF OLIG1 HSPG2 NSF POLR1D LRP1 CTBP2 PLCH1

4.78e-03111318615EFO_0004840
Diseasehematocrit

ACACA HOXD10 HOXD11 FGD5 CCDC157 APOA5 PLEKHA6 RGS14 FCGR2C TIE1 PDE8B XXYLT1 ANKRD17 CTBP2

5.03e-03101118614EFO_0004348
Diseasekidney volume

HOXD10 HOXD11

5.66e-03181862EFO_0600044
Diseasepneumonia, COVID-19

ACACA FYCO1 TYRP1 RAVER1

5.77e-031131864EFO_0003106, MONDO_0100096
DiseaseAlzheimer's disease (is_marker_for)

NBN STOX1 HSD17B3 GRIN2A CRH PRKCB

5.94e-032571866DOID:10652 (is_marker_for)
Diseasecoffee consumption measurement

PABPC4 BIRC6 PTPRF APOA5 CYP2G1P

6.05e-031821865EFO_0006781
Diseaseanorectal malformation

MUC5B KLHL17

6.30e-03191862MONDO_0019938
Diseaselevel of Sphingomyelin (d38:2) in blood serum

KANK3 ANKRD17

6.30e-03191862OBA_2045179

Protein segments in the cluster

PeptideGeneStartEntry
NLDIVIIGINPGLMA

TDG

131

Q13569
LALQMQRGRAPLGPQ

CCDC17

311

Q96LX7
MPEGLSPQQVVRRHI

ARHGEF10L

306

Q9HCE6
QEPLLQPLSLRVGML

C16orf89

81

Q6UX73
LAAMPGPRTLANLAE

CYP27C1

71

Q4G0S4
AQLFLEREGPPSLMQ

ASB9

246

Q96DX5
LLAGQPLPAEMTLAQ

BIRC6

3971

Q9NR09
RICEGIRPQIMNGPL

CTBP2

16

P56545
RMGNIIPLNVPREVT

CYP2J2

371

P51589
QLQGRIRVELMQPPD

CEACAM20

516

Q6UY09
ELPDSGALMLVPNRQ

AP4B1

611

Q9Y6B7
RIMKALANAGVPVPN

ACAD10

331

Q6JQN1
NLPAAQLQIAMGIPL

ACACA

456

Q13085
PQDPVGMRRQLQEEL

APOA5

86

Q6Q788
GPDPQMLSEEVRQRL

APOA5

271

Q6Q788
GAQLPPEVAAMARLL

COMMD5

26

Q9GZQ3
VPVVLLANKQDMPGA

ARL14

116

Q8N4G2
QTLLQLPPAMVEEGE

AQR

1381

O60306
EPVGPAAMNQLLLQL

ANKRD35

481

Q8N283
MVLCVQGPRPLLAVE

CISH

1

Q9NSE2
EELINMIPAIQRGDP

DMXL2

1611

Q8TDJ6
LNRAPRVPVQALPMV

ANKRD17

741

O75179
RPKDIINNPLFIMDG

CAPN11

111

Q9UMQ6
QAAGILLRLPQVAMA

CCNL1

91

Q9UK58
QLVQDSMGLRPLPAA

CCDC157

256

Q569K6
QMNRIVEVLGIPPAA

DYRK1B

321

Q9Y463
VEVLGIPPAAMLDQA

DYRK1B

326

Q9Y463
SRGPVLPEADQQMLR

ATG2B

1396

Q96BY7
QMNEPPGARARVALT

ATP5F1B

271

P06576
LRLKMPPQETALENG

ABCA7

1176

Q8IZY2
MRGLQQRVQDPPLQL

GMEB2

261

Q9UKD1
RAAQLPDMPLEELGQ

MUC5B

1381

Q9HC84
IQMLNEPPGELADIS

RAD23A

281

P54725
PPGRSMLAALIAAQA

RAVER1

301

Q8IY67
DPGMLVNIQQPLIRE

NR2C2

241

P49116
PIPGALDAVREMNDL

NT5C

76

Q8TCD5
MLEIDVQARDLGPNP

PCDH17

316

O14917
ELARGMLEPVQRPDV

HSPG2

621

P98160
QPGMVQPGRFQRALV

QRICH2

501

Q9H0J4
VDMAVTLPRGQLAAP

IQCN

651

Q9H0B3
QMGNEPPISLRRDLE

NUP205

426

Q92621
PAAQLQIAMGVPLHR

ACACB

601

O00763
VLNDPNMAGVPFLVL

ARL11

106

Q969Q4
GNILPPEVRGNLMAA

PAXIP1

301

Q6ZW49
AAPPQEQKQMLGERL

PABPC4

561

Q13310
FGMEQRLPPNSELVQ

LEFTY1

101

O75610
KAMAQLRVPQLGPRA

MADD

1081

Q8WXG6
AKAERPGLQNMELAP

LLGL2

681

Q6P1M3
PGLQNMELAPVQRKI

LLGL2

686

Q6P1M3
QLQGHRMVLQPVRSP

MGA

1781

Q8IWI9
RNPDENSRGMLPVAV

SPN

246

P16150
EHPPLMLQNRTVVGA

HIPK1

141

Q86Z02
LSQQVGMLERLAGPP

FYCO1

546

Q9BQS8
LRVDIPQQPMGIIAV

LRP1

2456

Q07954
MNVGTRPINLEPIFQ

KRT2

216

P35908
APGVNMQPVRVVILD

FREM2

2071

Q5SZK8
MQPVRVVILDDLGQP

FREM2

2076

Q5SZK8
MNDVNDLILEGPALP

KCNG4

501

Q8TDN1
LIAQDLQPMLEAPGR

JPH4

411

Q96JJ6
MDPQRSPLLEVKGNI

KIFC1

1

Q9BW19
EQGPAPLMVQLSLLR

MAP3K6

1156

O95382
RNHPVPVIAMVNGLA

ECHDC3

136

Q96DC8
KAAQFEPPGRQMIAI

FCGR2C

261

P31995
LNLLQPRPVVLQGMQ

PCNX3

721

Q9H6A9
LQGMQVRRVPLEIPE

PCNX3

731

Q9H6A9
IGDLMQRIQRVPQFP

FHIP2B

666

Q86V87
LGPFPAMENQVLVIR

MAP2K5

6

Q13163
INENVAAGMRFPLPE

PCDHGA10

146

Q9Y5H3
MDRVPTPQAIRAAQG

PGLYRP1

136

O75594
GDLERTVLQQNPIPM

PDE6A

746

P16499
RIGPMRLTQDPIQVL

PDE8B

121

O95263
MPLPVQVFNLQGAVE

GPS1

1

Q13098
QAPKLGLRAEENPMV

FGD5

376

Q6ZNL6
VMVLSRPGPLQRAQV

RASGRP4

256

Q8TDF6
MLNAREPKVVNGPEI

NSF

276

P46459
RVDENGPELLPRVAM

GCN1

1026

Q92616
LVRDAKNLVPMDPNG

PRKCB

176

P05771
KVPVSQRLNLPVMGA

PSRC1

331

Q6PGN9
QVVPHERQPGTEMLR

LAMA5

1661

O15230
PQQPQARPVLLRMGE

CRH

56

P06850
TMLRPQRPGDLQLGA

OLIG1

16

Q8TAK6
ILANGGPQALVQIMR

JUP

306

P14923
MAVGQQALPLNIIAP

MAS1L

66

P35410
IQTMNEIGVPLPRLL

NUP155

1286

O75694
LPPQRNMEVVLAVGP

IFT172

1326

Q9UG01
LGNADMIQPGLIPLQ

MLXIP

306

Q9HAP2
IVPNLEPEGRDLLMQ

CDK3

251

Q00526
LRPQQAQPRSDGEVM

DRAXIN

211

Q8NBI3
IVNMVDVAKALNRPP

EIF5

36

P55010
LQEMPGDVPLARIQR

ESPL1

1661

Q14674
LGTPTREQIREMNPN

GSK3A

336

P49840
VQEDIRPGLPMLRQI

GPATCH11

41

Q8N954
QARPAAPMEGAVQLL

KLHL17

46

Q6TDP4
GELPPELVQQMEGRR

CABIN1

1166

Q9Y6J0
LQAPPTRIGLINDMV

EIF3A

361

Q14152
AMDLEVPVLARNIPG

GLT1D1

261

Q96MS3
QAAGILLRLPQVAMA

CCNL2

86

Q96S94
LIQPLGAIMPISELQ

FMO5

371

P49326
VMLQLNPRGAAKPQL

HOXD10

176

P28358
EEAAMQRELLPPAGR

HOXD11

121

P31277
LPAVVRENAQLLNMP

HAUS3

336

Q68CZ6
PEQLPVADMRALLTG

ELMO3

591

Q96BJ8
EPEDGRLVQFLLMNP

BLMH

126

Q13867
AIVLNAMNLPPDKAR

FMNL2

36

Q96PY5
FGMEQRLPPNSELVQ

LEFTY2

101

O00292
TLQERQMLGLQGLLP

ME2

41

P23368
PGEEVTEANIRLPMQ

DSC1

741

Q08554
LPEEAQGPGRRMILL

DUX1

11

O43812
ASPGPAQLQLVREQM

KANK3

176

Q6NY19
NSILEIRGPGLQMLP

FLRT1

581

Q9NZU1
GLAPIQVVGQPVMAL

BICRA

231

Q9NZM4
RRVNLPVPMFEDNLG

CCDC8

171

Q9H0W5
GILVNNVGMLPNLLP

HSD17B3

126

P37058
MLQVVQEGNPAPFII

LINC01556

1

Q5JQF7
LGPNKMVVDLTDPNR

RILPL2

116

Q969X0
GSLAPLQDVAPMLQV

NRROS

501

Q86YC3
PNLEILMIGENPVIG

LRRN1

191

Q6UXK5
MSIQAPPRLLELAGQ

PRAMEF13

1

Q5VWM6
PRGLPIIQDVMLAEA

PTPRF

756

P10586
PQRLQGAARVFMPLQ

NRK

436

Q7Z2Y5
PLLHRVMGNQVFPEV

PKP1

626

Q13835
PAVEPFQRGLNELMN

POLR1D

91

P0DPB6
RGIEDNPMVVPLCNR

VARS1

651

P26640
IQNFQLPPGMVLVRS

TAF4

446

O00268
LPPGMVLVRSENGQL

TAF4

451

O00268
DPGLRNDTRNMPVQL

POLR3D

166

P05423
MAPLSEPNAVGIVIA

SORT1

476

Q99523
MVRLVLPNPGLDARI

SLC6A19

1

Q695T7
DRPRALVLVPQEGVM

SORL1

876

Q92673
LGQIELEGRRPPLMA

POLR1A

916

O95602
NIPLMRQRELQVGIP

SFXN3

191

Q9BWM7
GLLPVITPMAGNQRV

SLC38A3

21

Q99624
SQMRQELIDLRGPVP

SNX29

621

Q8TEQ0
ENMLCVGIVPGRRQP

PRSS58

176

Q8IYP2
MLARGQPLPETLQLA

SMARCA2

191

P51531
RPGLMNVPRVEAIQD

PPARD

361

Q03181
VPQGMAFALLANLPA

SLC26A9

86

Q7LBE3
ELIQRNLSPALGQMP

F5

1216

P12259
MLQRQGLRPIPEAEI

NBN

296

O60934
MSIQAPPRLLELAGQ

PRAMEF14

1

Q5SWL7
QIRQNIVDLGGLPIM

ODAD2

526

Q5T2S8
EQEAGMLLPRDQPLD

OPLAH

56

O14841
LQMAGPQETVLALPL

FAM178B

31

Q8IXR5
PIIDGIPNMIPQAAR

PYURF

86

Q96I23
LFGLLQEVARIQPMP

NEPRO

201

Q6NW34
ALDIQDPGVPRLKNM

SEMA4A

86

Q9H3S1
RSRLIQMLGEPLVPQ

SIMC1

826

Q8NDZ2
MLENVQQELVGEPRP

SECISBP2

776

Q96T21
MPQLPVAVPQQGLRL

TANC2

1591

Q9HCD6
MSIQAPPRLLELAGQ

PRAMEF1

1

O95521
LLPPAMTQQLRGDGL

HRC

21

P23327
LQMAAEPISARQPAL

ISL1

156

P61371
MSIQAPPRLLELAGQ

PRAMEF2

1

O60811
MRRVCLPAPQLQGNI

POU4F3

31

Q15319
DLRAVNAVIQPMGPL

ERVK-9

1011

P63128
MAGPQPLALQLEQLL

AATF

1

Q9NY61
IQRLVDIVPMGVPHN

CYP2G1P

11

Q6ZSU1
PQPQGVLRADILDQM

ASPA

181

P45381
VIIDMNDPSNPIRRP

CLTC

51

Q00610
NAPEGLPQLMEVVRS

CNOT1

1801

A5YKK6
PGPRKQMDINAAIQA

COL24A1

1476

Q17RW2
NGVPIARAVLVDMEP

TUBD1

56

Q9UJT1
QAMGEAARVQIPPAQ

PLEKHA6

151

Q9Y2H5
LVNMLNLEPVPSGAR

TGFBRAP1

101

Q8WUH2
EFLRLAMPQPVNPQL

TRIM77

256

I1YAP6
RPMVQRLPEPQDVAQ

TYRP1

321

P17643
VLLADPGPVNFMVRL

YIPF6

171

Q96EC8
AVMGRFPQLLDPQQL

ZC3H12A

571

Q5D1E8
QVPEPRLMQRVALDA

SLC26A1

331

Q9H2B4
LGMIPNDVQGPSLLI

PATJ

986

Q8NI35
NRNILIQMDLPLVPG

SCN10A

1781

Q9Y5Y9
ERPPFAQIALQLGRM

TIE1

1096

P35590
MARPVQLAPGSLALV

STOX1

1

Q6ZVD7
MAQALGEDLVQPPEL

TBC1D10C

1

Q8IV04
LEGVMNQADAPRPLN

TRPM3

26

Q9HCF6
MEPRNLALVFGPTLV

ARHGAP23

1051

Q9P227
EDPAVIMRGTPQIQR

ARHGAP25

326

P42331
PELGPRLAAMLNFNL

UBE4B

1111

O95155
GPVPEQMLAQARVPL

TEDC1

121

Q86SX3
QVDAAIGLLMPPLQT

THAP1

111

Q9NVV9
NMKLEAVNPRNPGEL

SFMBT2

411

Q5VUG0
RIAQCLNVPVNGPML

TIGD4

96

Q8IY51
LNVPVNGPMLRLKAN

TIGD4

101

Q8IY51
LGNLRPPSLLQGEVM

VWCE

351

Q96DN2
MERAVPLAVPLGQTE

THOC6

1

Q86W42
LNPVQRPEMFIIGAQ

WNT5B

31

Q9H1J7
EPQSGRVQGMQPLLL

TEX13C

211

A0A0J9YWL9
VLAEPRPDMFRAQQL

RGS14

146

O43566
NGPDGRRVMQPQILE

TTLL12

591

Q14166
MPVDRNLLGALSLPV

PLCH1

971

Q4KWH8
PVQLEILRRAGAMPI

SKOR2

96

Q2VWA4
VDLGTPQAEIARNMP

SYMPK

326

Q92797
KNPERNLPLAIGISM

SLC7A6

261

Q92536
QMAEVLPSPRGQRVI

TOP2A

1206

P11388
VVAVDLQAMAPLPGV

FTSJ1

71

Q9UET6
LQAMAPLPGVVQIQG

FTSJ1

76

Q9UET6
FLRPGQRLQPMLVQA

VWA5B2

501

Q8N398
MIAKNVLGLVPQALP

ZNF687

436

Q8N1G0
TNQLLRPLGIEMPLQ

PIPOX

206

Q9P0Z9
EMVLKGQRLPQALAP

VPS37B

161

Q9H9H4
MAAPPQLRALLVVVN

PXMP4

1

Q9Y6I8
RELIPNIPFQMLLRG

PC

631

P11498
LNPVLPVAIMASAQP

ZNF318

1496

Q5VUA4
LLPLDMQGNQILVFP

ZBTB22

416

O15209
MPPAVLKNLAEAVRG

VWA3A

306

A6NCI4
LPGAIIGIAREMQPV

XXYLT1

246

Q8NBI6
AGLPLDVNVVALLMN

GRIN2A

61

Q12879