Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC6A4 ABCA2 SLC8B1 CLCN6 SLC31A2 PSG4 HPX SLC17A4 KCNMA1 SLC47A1 SLC35F2 GRIN2A SLC7A11 CNGB1 AQP7 ABCB1

1.76e-0511808116GO:0022857
GeneOntologyMolecularFunctionceramide floppase activity

ABCA2 ABCB1

4.86e-053812GO:0099038
GeneOntologyMolecularFunctiontransporter activity

SLC6A4 ABCA2 SLC8B1 CLCN6 SLC31A2 PSG4 HPX SLC17A4 KCNMA1 SLC47A1 SLC35F2 GRIN2A SLC7A11 CNGB1 AQP7 ABCB1

5.14e-0512898116GO:0005215
GeneOntologyMolecularFunctionolfactory receptor activity

OR7D4 OR1M1 OR7C2 OR7C1 OR1E1 OR7G3 OR7G2 OR7A2P OR2W6P

6.18e-05431819GO:0004984
GeneOntologyMolecularFunctionsphingolipid floppase activity

ABCA2 ABCB1

9.70e-054812GO:0046623
GeneOntologyMolecularFunctiondolichyl-diphosphooligosaccharide-protein glycotransferase activity

STT3A STT3B

1.61e-045812GO:0004579
GeneOntologyMolecularFunctionoligosaccharyl transferase activity

STT3A STT3B

1.61e-045812GO:0004576
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR7D4 VIPR1 OR1M1 OR7C2 OR7C1 ADGRB3 OR1E1 ADGRE5 OR7G3 OR7G2 OR7A2P OR2W6P

2.23e-048848112GO:0004930
GeneOntologyMolecularFunctionantiporter activity

SLC6A4 SLC8B1 CLCN6 SLC47A1 SLC7A11

2.46e-04138815GO:0015297
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR7D4 VIPR1 OR1M1 IGF2R OR7C2 NRXN2 OR7C1 ADGRB3 OR1E1 ADGRE5 GRIN2A OR7G3 OR7G2 OR7A2P OR2W6P

3.16e-0413538115GO:0004888
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC6A4 ABCA2 SLC8B1 CLCN6 SLC17A4 SLC47A1 SLC7A11 ABCB1

6.99e-04477818GO:0022804
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC6A4 SLC8B1 CLCN6 SLC31A2 SLC17A4 KCNMA1 SLC47A1 GRIN2A CNGB1 AQP7

9.64e-047588110GO:0015318
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC6A4 SLC8B1 CLCN6 SLC17A4 SLC47A1 SLC7A11

1.29e-03296816GO:0015291
GeneOntologyMolecularFunctionendopeptidase regulator activity

ABCA2 A2ML1 C5 NLRP2 PROS1

1.36e-03201815GO:0061135
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

PSG4 SLC47A1 GRIN2A SLC7A11 ABCB1

1.54e-03207815GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

PSG4 SLC47A1 GRIN2A SLC7A11 ABCB1

1.58e-03208815GO:0005342
GeneOntologyMolecularFunctionfloppase activity

ABCA2 ABCB1

1.88e-0316812GO:0140328
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR7D4 OR1M1 OR7C2 OR7C1 OR1E1 OR7G3 OR7G2 CNGB1 OR7A2P OR2W6P

9.10e-064328310GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR7D4 OR1M1 OR7C2 OR7C1 OR1E1 OR7G3 OR7G2 CNGB1 OR7A2P OR2W6P

1.72e-054658310GO:0007608
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR7D4 OR1M1 OR7C2 OR7C1 OR1E1 GRIN2A OR7G3 OR7G2 CNGB1 OR7A2P OR2W6P

2.11e-055828311GO:0050906
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR7D4 OR1M1 OR7C2 OR7C1 OR1E1 OR7G3 OR7G2 CNGB1 OR7A2P OR2W6P

2.47e-054858310GO:0050907
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR7D4 OR1M1 OR7C2 OR7C1 OR1E1 OR7G3 OR7G2 CNGB1 OR7A2P OR2W6P

4.74e-055248310GO:0009593
GeneOntologyBiologicalProcessco-translational protein modification

STT3A STT3B

4.79e-053832GO:0043686
GeneOntologyBiologicalProcessceramide translocation

ABCA2 ABCB1

4.79e-053832GO:0099040
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR7D4 OR1M1 OR7C2 OR7C1 OR1E1 OR7G3 OR7G2 CNGB1 OR7A2P OR2W6P

6.79e-055478310GO:0007606
GeneOntologyBiologicalProcessdetection of stimulus

OR7D4 OR1M1 OR7C2 OR7C1 OR1E1 GRIN2A OR7G3 OR7G2 CNGB1 OR7A2P OR2W6P

1.46e-047228311GO:0051606
GeneOntologyBiologicalProcesssphingolipid translocation

ABCA2 ABCB1

1.59e-045832GO:0099039
GeneOntologyBiologicalProcessadult behavior

SLC6A4 NRXN2 KCNMA1 SEZ6L2 SLC7A11 AGTPBP1

1.70e-04203836GO:0030534
GeneOntologyCellularComponentendoplasmic reticulum membrane

OR7C2 OR7C1 SPTLC2 CYP8B1 MACO1 GRIN2A UBIAD1 LRBA SEZ6L2 OR7A2P TMEM86A STT3A STT3B PROS1 OR2W6P

1.56e-0412938315GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

OR7C2 OR7C1 SPTLC2 CYP8B1 MACO1 GRIN2A UBIAD1 LRBA SEZ6L2 OR7A2P TMEM86A STT3A STT3B PROS1 OR2W6P

1.64e-0412998315GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

OR7C2 OR7C1 SPTLC2 CYP8B1 MACO1 GRIN2A UBIAD1 LRBA SEZ6L2 OR7A2P TMEM86A STT3A STT3B PROS1 OR2W6P

2.07e-0413278315GO:0042175
DomainSTT3

STT3A STT3B

1.90e-052822PF02516
DomainOligo_trans_STT3

STT3A STT3B

1.90e-052822IPR003674
DomainOlfact_rcpt

OR7D4 OR1M1 OR7C2 OR7C1 OR1E1 OR3A4P OR7G3 OR7G2

3.28e-04393828IPR000725
DomainGPCR_2_secretin-like_CS

VIPR1 ADGRB3 ADGRE5

4.42e-0434823IPR017983
DomainA2M_N_2

A2ML1 C5

5.24e-048822SM01359
Domain-

A2ML1 C5

5.24e-0488222.60.40.690
DomainA2M_recep

A2ML1 C5

5.24e-048822SM01361
DomainA2M

A2ML1 C5

5.24e-048822SM01360
DomainA2M_N

A2ML1 C5

8.38e-0410822PF01835
DomainA2M_N

A2ML1 C5

8.38e-0410822IPR002890
DomainA-macroglobulin_rcpt-bd

A2ML1 C5

8.38e-0410822IPR009048
DomainALPHA_2_MACROGLOBULIN

A2ML1 C5

8.38e-0410822PS00477
DomainA2M

A2ML1 C5

8.38e-0410822PF00207
DomainA2M_N_2

A2ML1 C5

8.38e-0410822IPR011625
DomainA2M_comp

A2ML1 C5

8.38e-0410822IPR011626
DomainA2M_N_2

A2ML1 C5

8.38e-0410822PF07703
DomainA2M_recep

A2ML1 C5

8.38e-0410822PF07677
DomainA2M_comp

A2ML1 C5

8.38e-0410822PF07678
DomainMacroglobln_a2

A2ML1 C5

8.38e-0410822IPR001599
Domain-

A2ML1 C5

1.22e-03128221.50.10.20
DomainG_PROTEIN_RECEP_F2_2

VIPR1 ADGRB3 ADGRE5

1.38e-0350823PS00650
Domain7tm_2

VIPR1 ADGRB3 ADGRE5

1.38e-0350823PF00002
DomainGPCR_2_secretin-like

VIPR1 ADGRB3 ADGRE5

2.33e-0360823IPR000832
DomainGPCR_2-like

VIPR1 ADGRB3 ADGRE5

2.33e-0360823IPR017981
DomainG_PROTEIN_RECEP_F2_4

VIPR1 ADGRB3 ADGRE5

2.44e-0361823PS50261
DomainTerpenoid_cyclase/PrenylTrfase

A2ML1 C5

2.78e-0318822IPR008930
DomainAAA+_ATPase

ABCA2 HELZ2 DNAH7 ABCB1

3.72e-03144824IPR003593
DomainAAA

ABCA2 HELZ2 DNAH7 ABCB1

3.72e-03144824SM00382
DomainHormR

VIPR1 ADGRB3

5.35e-0325822SM00008
DomainHRM

VIPR1 ADGRB3

6.68e-0328822PF02793
Domain-

NRXN2 LRBA PROS1

8.45e-03958232.60.120.200
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR7D4 OR1M1 OR7C2 OR7C1 OR1E1 OR3A4P OR7G3 OR7G2 OR7A2P

3.59e-0921985912213199
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR7D4 OR1M1 OR7C2 OR7C1 OR1E1 OR7G3 OR7G2 OR7A2P OR2W6P

1.57e-0734085911875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR7D4 OR1M1 OR7C2 OR7C1 OR1E1 OR7G3 OR7G2 OR7A2P OR2W6P

1.57e-0734085911802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR7D4 OR1M1 OR7C2 OR7C1 OR1E1 OR7G3 OR7G2 OR7A2P OR2W6P

1.69e-0734385932295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR7D4 OR1M1 OR7C2 OR7C1 OR1E1 OR7G3 OR7G2 OR7A2P OR2W6P

1.82e-0734685914611657
Pubmed

The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.

OR7C2 OR7C1 OR1E1 OR7A2P

2.84e-072385410706615
Pubmed

Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

OR1M1 OR7C1 OR1E1 OR7A2P

3.40e-07248549119360
Pubmed

The human olfactory receptor gene family.

OR7D4 OR1M1 OR7C2 OR7C1 OR1E1 OR3A4P OR7G3 OR7G2 OR7A2P OR2W6P

8.41e-07541851014983052
Pubmed

Odorant and vomeronasal receptor genes in two mouse genome assemblies.

OR7C2 OR7C1 OR1E1 OR7G3 OR7G2

1.09e-067485515081110
Pubmed

Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters.

SLC6A4 GRIN2A

5.90e-06285211487658
Pubmed

The down-regulation of SLC7A11 enhances ROS induced P-gp over-expression and drug resistance in MCF-7 breast cancer cells.

SLC7A11 ABCB1

5.90e-06285228630426
Pubmed

Mutations in STT3A and STT3B cause two congenital disorders of glycosylation.

STT3A STT3B

5.90e-06285223842455
Pubmed

Quantitative glycoproteomics reveals new classes of STT3A- and STT3B-dependent N-glycosylation sites.

STT3A STT3B

5.90e-06285231296534
Pubmed

The middle X residue influences cotranslational N-glycosylation consensus site skipping.

STT3A STT3B

5.90e-06285225029371
Pubmed

Proteome and Glycoproteome Analyses Reveal the Protein N-Linked Glycosylation Specificity of STT3A and STT3B.

STT3A STT3B

5.90e-06285236139350
Pubmed

Association between olfactory receptor genes, eating behavior traits and adiposity: results from the Quebec Family Study.

OR7D4 OR7G3

5.90e-06285222044667
Pubmed

Mammalian STT3A/B oligosaccharyltransferases segregate N-glycosylation at the translocon from lipid-linked oligosaccharide hydrolysis.

STT3A STT3B

5.90e-06285230181269
Pubmed

Chromosomal location-dependent nonstochastic onset of odor receptor expression.

OR7D4 OR7G2 OR7A2P

9.35e-061785320668191
Pubmed

STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion.

STT3A STT3B

1.77e-05385229765039
Pubmed

Cotranslational and posttranslational N-glycosylation of polypeptides by distinct mammalian OST isoforms.

STT3A STT3B

1.77e-05385219167329
Pubmed

Tethered agonist exposure in intact adhesion/class B2 GPCRs through intrinsic structural flexibility of the GAIN domain.

ADGRB3 ADGRE5

1.77e-05385233497605
Pubmed

mRNA expression profile of multidrug-resistant genes in acute lymphoblastic leukemia of children, a prognostic value for ABCA3 and ABCA2.

ABCA2 ABCB1

3.53e-05485224145140
Pubmed

Keratinocyte-associated protein 2 is a bona fide subunit of the mammalian oligosaccharyltransferase.

STT3A STT3B

3.53e-05485222266900
Pubmed

Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin.

DIP2A GRIN2A ELP3

4.42e-052885331600191
Pubmed

The oligosaccharyltransferase subunits OST48, DAD1 and KCP2 function as ubiquitous and selective modulators of mammalian N-glycosylation.

STT3A STT3B

5.87e-05585222467853
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

IGF2R SPTLC2 MACO1 UBIAD1 LRBA ELP3 RAB27B STT3A STT3B

6.67e-0571985935337019
Pubmed

The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.

IGF2R SPTLC2 MACO1 RAB27B STT3B

7.41e-0517685528692057
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

IGF2R SLC35F2 UBIAD1 LRBA SLC7A11 RAB27B STT3B ABCB1

7.79e-0556985830639242
Pubmed

OST4 is a subunit of the mammalian oligosaccharyltransferase required for efficient N-glycosylation.

STT3A STT3B

8.80e-05685223606741
Pubmed

Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties.

STT3A STT3B

8.80e-05685212887896
Pubmed

Differential expression of intestinal membrane transporters in cholera patients.

SLC6A4 SLC7A11

1.23e-04785217575980
Pubmed

Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans.

SLC6A4 ABCB1

1.23e-04785219844206
Pubmed

FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration.

SACS AGTPBP1 ABCB1

1.51e-044285329348145
Pubmed

Failure to replicate genetic associations with antidepressant treatment response in duloxetine-treated patients.

SLC6A4 ABCB1

1.64e-04885220110084
Pubmed

Dynamic and transient interactions of Atg9 with autophagosomes, but not membrane integration, are required for autophagy.

IGF2R WIPI2

1.64e-04885222456507
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

COL4A4 ABCA2 IGF2R SPTLC2 ADGRE5 UBIAD1 SEZ6L2 SLC7A11 STT3A STT3B PROS1

1.64e-041201851135696571
Pubmed

Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain microvessels.

ABCA2 ABCB1

2.10e-04985221707071
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

CLCN6 NRXN2 HELZ2 ADGRB3 PCNX1

2.33e-0422585512168954
Pubmed

Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations.

IGF2R STT3B

2.62e-041085220541250
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

IGF2R SPTLC2 MACO1 IMMP1L ADGRE5 C5 UBIAD1 LRBA STT3A PROS1

2.64e-041061851033845483
Pubmed

Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins.

NRXN2 ADGRB3 ADGRE5

2.86e-045285324613359
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

VIPR1 SLC8B1 IGF2R PCNX1 NNT AGTPBP1

3.05e-0437185615747579
Pubmed

The IL-2 receptor beta chain gene (Il-2rb) is closely linked to the Pdgfb locus on mouse chromosome 15.

PSG4 C5 HAL

3.19e-04548538482578
Pubmed

Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire.

OR1E1 OR3A4P

3.20e-04118528004088
Pubmed

Cryo-electron microscopy structures of human oligosaccharyltransferase complexes OST-A and OST-B.

STT3A STT3B

3.20e-041185231831667
Pubmed

CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroligins.

NRXN2 GRIN2A

3.20e-04118529647694
Pubmed

Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits.

STT3A STT3B

3.83e-041285215835887
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

MACO1 A2ML1 HPX HELZ2 C5 HAL RAB27B STT3B

4.29e-0473285834732716
Pubmed

Alternative splice variants encoding unstable protein domains exist in the human brain.

ABCA2 NRXN2

4.52e-041385215491607
Pubmed

Disturbance of cerebellar synaptic maturation in mutant mice lacking BSRPs, a novel brain-specific receptor-like protein family.

GRIN2A SEZ6L2

4.52e-041385216814779
Pubmed

Evolution of odorant receptors expressed in mammalian testes.

OR1E1 OR7A2P

4.52e-041385211014824
Pubmed

Candidate gene polymorphisms for ischemic stroke.

SLC6A4 CLCN6 C5

5.27e-046485319729601
Pubmed

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.

SLC35F2 GRIN2A STT3A

5.52e-046585323453885
Pubmed

Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse.

VIPR1 NRXN2 GRIN2A

6.03e-046785316987237
Pubmed

Sequence, structure, and evolution of a complete human olfactory receptor gene cluster.

OR1E1 OR3A4P

6.93e-041685210673334
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

ABCA2 IGF2R STT3A STT3B

7.17e-0416485432409323
Pubmed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

SLC6A4 VIPR1 NRXN2 GRIN2A ABCB1

8.63e-0430085519086053
Pubmed

Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters.

SLC47A1 ABCB1

8.80e-041885231791063
Pubmed

IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2α.

NRXN2 GRIN2A

8.80e-041885228864826
Pubmed

Proteome-wide characterization of N-glycosylation events by diagonal chromatography.

PSG4 A2ML1 C5

9.04e-047785316944957
Pubmed

GGA2 and RAB13 promote activity-dependent β1-integrin recycling.

IGF2R RPS6KA1

9.83e-041985231076515
Pubmed

Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition.

ABCA2 ABCB1

1.09e-032085221072184
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

IGF2R SPTLC2 MACO1 PCNX1 UBIAD1 STT3A STT3B

1.15e-0365785736180527
Pubmed

A series of recombinant inbred strains between the BALB/cHeA and STS/A mouse strains.

C5 HAO1

1.20e-03218524042679
Pubmed

Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model.

ABCA2 ABCB1

1.20e-032185223137377
Pubmed

PEG3 binds to H19-ICR as a transcriptional repressor.

IGF2R SLC35F2

1.32e-032285227824289
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

IGF2R SPTLC2 UBIAD1 SLC7A11 STT3A STT3B

1.42e-0349985622810586
Pubmed

Chromosomal localization of the proteasome Z subunit gene reveals an ancient chromosomal duplication involving the major histocompatibility complex.

ABCA2 C5

1.44e-03238528799160
Pubmed

IL-23/IL-17A/TRPV1 axis produces mechanical pain via macrophage-sensory neuron crosstalk in female mice.

C5 NNT

1.44e-032385234473953
Pubmed

Mapping the mammalian ribosome quality control complex interactome using proximity labeling approaches.

ADSS2 RPS6KA1 HPX WIPI2

1.55e-0320285429540532
Pubmed

Evolutionarily conserved regulators of tau identify targets for new therapies.

IGF2R ADSS2 SPTLC2 LRBA STT3A STT3B

1.69e-0351685636610398
Pubmed

TNF deficiency causes alterations in the spatial organization of neurogenic zones and alters the number of microglia and neurons in the cerebral cortex.

SLC6A4 NNT

1.99e-032785231505254
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

NRXN2 PCNX1 DNAH7

2.03e-0310285310231032
Pubmed

Distribution of olfactory receptor genes in the human genome.

OR7C2 OR1E1

2.14e-03288529500546
Pubmed

Candidate gene analysis in an on-going genome-wide association study of attention-deficit hyperactivity disorder: suggestive association signals in ADRA1A.

SLC6A4 GRIN2A

2.14e-032885219352218
Pubmed

The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth.

IGF2R ERVW-1

2.14e-032885234963058
Pubmed

Defining the membrane proteome of NK cells.

ABCA2 IGF2R HELZ2 ADGRE5 IFT122 LRBA NNT STT3A STT3B

2.21e-03116885919946888
CytobandEnsembl 112 genes in cytogenetic band chr19p13

OR7D4 OR1M1 OR7C2 OR7C1 ADGRE5 OR7G3 OR7G2 OR7A2P

1.18e-04797858chr19p13
GeneFamilyOlfactory receptors, family 7

OR7D4 OR7C2 OR7C1 OR7G3 OR7G2 OR7A2P

1.46e-06113576154
GeneFamilySTT3 oligosaccharyltransferase catalytic subunits|Oligosaccharyltransferase complex subunits

STT3A STT3B

9.77e-062572444
GeneFamilySolute carriers

SLC6A4 SLC8B1 SLC31A2 SLC17A4 SLC47A1 SLC35F2 SLC7A11

2.32e-04395577752
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

A2ML1 C5

3.47e-0495721234
GeneFamilyOligosaccharyltransferase complex subunits

STT3A STT3B

6.32e-0412572445
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA2 IRF8 ADGRE5 RAB27B ABCB1 NCR3

1.94e-0619684608714b70ddaee7d11397c1dd4a287d412edd90f7
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA2 IRF8 ADGRE5 RAB27B ABCB1 NCR3

1.94e-061968465bcc959db7deb34d5a32d3464367d47d4945cdaf
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA2 IRF8 ADGRE5 RAB27B ABCB1 NCR3

2.00e-06197846f84263c5aaf3a5cd46d6e06358e8de6c6e6eaa3b
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Airway-Club|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

A2ML1 ARHGEF38 SLC17A4 MS4A8 C5 HEPHL1

2.06e-061988466712216c5a7fd86b68fd45b0ff7794975f19774e
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-MAIT|GI_small-bowel / Manually curated celltypes from each tissue

NRXN2 HPX HAO1 AQP7 NCR3

8.44e-061468451cb2e157222631e8915d89b255a843d16d7d99cc
ToppCellCOVID-19-kidney-PCT-S3-2|kidney / Disease (COVID-19 only), tissue and cell type

CYP8B1 HPX C5 HAL HAO1

1.97e-051748455aa2fb631505600f37d2b87b02def7be139dc262
ToppCellCOVID-19-kidney-PCT-S3-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

CYP8B1 HPX C5 HAL HAO1

2.08e-05176845b6497324e3e52f514ce556a3fa0c3011c45dcc7b
ToppCellfacs-Marrow-B-cells-18m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8B1 NRXN2 RPS6KA1 IRF8 TMEM86A

2.38e-05181845e6c78038b14100e0c9c6fe25e8f0b75c02c33549
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4|TCGA-Thryoid / Sample_Type by Project: Shred V9

IGF2R ADSS2 PSG4 SLC35F2 PROS1

2.57e-05184845d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCellTCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma-6|TCGA-Skin / Sample_Type by Project: Shred V9

CDSN A2ML1 UNC93A HAL HEPHL1

2.78e-051878452ca7928baf0c5e61f7294ed05e6e6f0e0adf9d3f
ToppCellCOVID-NK-|COVID / Condition, Cell_class and T cell subcluster

COL4A4 ABCA2 RAB27B ABCB1 NCR3

2.85e-05188845fabdd68a9734d35e75e1f4a4bfd5c531cfc099f1
ToppCellCOVID-NK|COVID / Condition, Cell_class and T cell subcluster

COL4A4 ABCA2 RAB27B ABCB1 NCR3

2.85e-051888450beaa671611110a11e46156f54f5202cc24967a4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DIP2A ABCA2 IGF2R RPS6KA1 NCR3

3.23e-05193845b53ffef20f918b7d1e9d3924562691d13245e2dd
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-innate_lymphocytic|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DIP2A ADGRE5 RAB27B ABCB1 NCR3

3.65e-05198845326e97bdc27cc3440f5488c2519446580cdc9d51
ToppCellCOVID_non-vent-Lymphocytic-ILC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

DIP2A ABCA2 IGF2R ABCB1 NCR3

3.74e-05199845df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCellCOVID_vent-Lymphocytic-ILC|COVID_vent / Disease condition, Lineage, Cell class and subclass

DIP2A IGF2R RAB27B ABCB1 NCR3

3.74e-05199845e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCellCOVID_non-vent-Lymphocytic-ILC-NK_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

DIP2A ABCA2 IGF2R ABCB1 NCR3

3.74e-05199845ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCellTransverse-T_cell-Tfh|Transverse / Region, Cell class and subclass

VIPR1 SLC66A2 OR7C1 MGARP PROS1

3.74e-05199845cbef8f95edf2e86e16c448a76068d7ed8f6b7748
ToppCellTransverse-(1)_T_cell-(16)_Tfh|Transverse / shred on region, Cell_type, and subtype

VIPR1 SLC66A2 OR7C1 MGARP PROS1

3.74e-05199845aa31e26d48066f865ca33251a33a28934c0a7a44
ToppCellCOVID_vent-Lymphocytic-ILC-NK_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

DIP2A IGF2R RAB27B ABCB1 NCR3

3.74e-051998455f914962e2572b0c6372465b81b7496fa663d93c
ToppCellbackground-Hepatocytes|World / Sample and Cell Type and Tumor Cluster (all cells)

CYP8B1 HPX HAL HAO1 PROS1

3.83e-05200845423cca10df6ae0489a8fe7e7df87e70364dac022
ToppCellbackground-Hepatocytes|background / Sample and Cell Type and Tumor Cluster (all cells)

CYP8B1 HPX C5 HAL PROS1

3.83e-05200845787d35b5c2f2ad967ae14e99496a0299ac7e72fd
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

A2ML1 ARHGEF38 MS4A8 HEPHL1 DNAH7

3.83e-05200845da12821e8a0657869ca0f75d351cce2d7605a505
ToppCellLPS_IL1RA_TNF-Epithelial_airway|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

A2ML1 ARHGEF38 MS4A8 HEPHL1 DNAH7

3.83e-0520084572c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCellControl-Epithelial_alveolar-Mes-Like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAP3K15 C5 HAL RAB27B

6.90e-05116844df7609503782d8d7e4f31ed2a626916e5474d5bc
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-8|TCGA-Lung / Sample_Type by Project: Shred V9

HPX C5 HAL ENTPD8

1.31e-0413784405ca83c30e3dbe74c81278b3636d57da2c20b458
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC8B1 ADGRB3 TMEM86A AGTPBP1

1.55e-041438444a0f26eef935fe68a1da5d319503059a8a8682dd
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC8B1 ADGRB3 TMEM86A AGTPBP1

1.55e-0414384465328a0a2f3972fac596e07933e74b2ef7cceb84
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADSS2 ARHGEF38 HAL RAB27B

1.77e-041488449fe3c0a5904b8e9a0f28130f8d84d4f2a819b06c
ToppCell368C-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

RANBP17 COL4A4 DNAH7 RAB27B

1.81e-04149844f53151d9e5e724a61be0ee6a8c740d1990f28d5f
ToppCell368C-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

RANBP17 COL4A4 DNAH7 RAB27B

1.81e-041498449286bc56ff2e245630537a0bda5f1a1e17be863a
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Mast|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC6A4 SLC31A2 RAB27B ABCB1

1.91e-041518449702575e47ececcf0a9f0f20a4a920dbb1ba5657
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGF2R MGARP DNAH7 NCR3

1.91e-041518440cc2f4aec3dae4603fa831f22c40f897e68b34e2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGF2R MGARP DNAH7 NCR3

1.91e-04151844b545823113a3450c5f841f7de48bf0937593544f
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC6A4 SLC31A2 RAB27B ABCB1

1.91e-04151844673e4ab117b723c14d1df3804bbedc9e48284a9d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A4 ARHGEF38 MAP3K15 AQP7

1.91e-04151844f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

OR1M1 PSG4 UNC93A SLC7A11

2.11e-0415584429c4e9947bb4f7e257ed5c3bcf21bd67f88d473f
ToppCellAT1-AT2_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

SLC6A4 COL4A4 C5 HAL

2.11e-04155844010e45ef4b505bf419ea41e4d1619521d1c78319
ToppCellfacs-Skin-nan-24m-Epithelial-inner_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A4 KCNMA1 IRF8 MAP3K15

2.11e-04155844fa2776d258e0420b2895de1008e292ad7725dac0
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP8B1 SLC17A4 SLC47A1 ENTPD8

2.16e-04156844e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Mast|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC6A4 RPS6KA1 RAB27B ABCB1

2.38e-041608446393e3d5c5c8176c93aecd89b313bd054a00d474
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC6A4 RPS6KA1 RAB27B ABCB1

2.38e-041608442065938e944eb99478fd8132c2c03adeaee6d447
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC8B1 SLC31A2 CYP8B1 IRF8

2.44e-04161844afc719ffa53ab34c5628da47936da1f731dceab1
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-NK_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IRF8 ADGRE5 ABCB1 NCR3

2.80e-041678442ca1b994583edf4e197535ffac8fb0c1142f0dc1
ToppCellBronchial_Biopsy-Immune-T_and_NK|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

FSIP2 HPX RAB27B NCR3

2.87e-04168844435b2f238fbb3f50427e8cdecf2220615015153c
ToppCellTCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma|TCGA-Cervix / Sample_Type by Project: Shred V9

ARHGEF38 MS4A8 DNAH7 ENTPD8

3.00e-04170844d682178d11d67eb5a02d0c6b3967645e37bcc62a
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Ndrg2_(Ndrg2)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

HPX UNC93A MS4A8

3.01e-04698433f6902cb62d6130b3d3a1cf122dbc695f7349ffe
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Ndrg2_(Ndrg2)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

HPX UNC93A MS4A8

3.01e-0469843832ed163f553481b49bbf8a1eb10cbd8afab4e34
ToppCelldroplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRXN2 RPS6KA1 IRF8 AQP7

3.14e-04172844422d311bba2dd5d8bece4e96ee8c86e78086b62d
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANBP17 FSIP2 KIF3C RAB27B

3.14e-0417284413d7117f92a92d77d6b4335ed800c585dc8b4511
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANBP17 FSIP2 KIF3C RAB27B

3.14e-041728443d83b2f03ad3af4dae3fe6cc0a0ef356872ca94f
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANBP17 FSIP2 KIF3C RAB27B

3.14e-04172844a3d431aed12c1192e8dca1dc85b8340fb7354f8d
ToppCelldroplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRXN2 RPS6KA1 IRF8 AQP7

3.14e-041728441abb6fbb28c8aff384540493d0f70eeacaa751f4
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANBP17 FSIP2 KIF3C RAB27B

3.14e-04172844028a5441242b2cc760cafc1822120180619c63ae
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANBP17 FSIP2 KIF3C RAB27B

3.14e-041728449fc70b1a143a8ec910336c23b761d908bb6aecb2
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC6A4 HPX SEZ6L2 AQP7

3.21e-0417384466488d01e03264fb193285470901c9c4182fbae8
ToppCellTCGA-Liver|World / Sample_Type by Project: Shred V9

CYP8B1 HPX C5 HAO1

3.28e-04174844452932f08cf53e5949672a025d78cecb874aa4b0
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic-Paneth|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGEF38 SEZ6L2 ENTPD8 MGAM2

3.35e-04175844bffa623511ceb0b9bf76d87f9a10cfadfe0e940f
ToppCellNS|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

A2ML1 IRF8 SLC7A11 NCR3

3.72e-041808448472dcce7bc0b7ce428ec17ddf0018f3258f78d2
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC31A2 KCNMA1 IRF8 SLC47A1

3.96e-04183844103c4c4595d8daa677679fd2fa1e99cd398e56dd
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

DIP2A IGF2R MS4A8 PCNX1

4.05e-04184844791f1bcb954aadc63d4117c400537d036f68734d
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL4A4 SLC35F2 SLC7A11 MGAM2

4.13e-04185844fec16a5e527fdef32d25957451b6e8ee9796cafd
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RANBP17 ARHGEF38 HAL SLC7A11

4.22e-04186844acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCA2 ADGRE5 ABCB1 NCR3

4.22e-04186844c984e5729958237b101df96d1c89a236faacded6
ToppCell368C-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DNAJC27 ELP3 NLRP2 ABCB1

4.30e-04187844c667fae6440dc98072b584f203d00f0fb1cb2f21
ToppCell368C-Lymphocytic-NK_cells-NK_cell_D3|368C / Donor, Lineage, Cell class and subclass (all cells)

DNAJC27 NLRP2 ABCB1 NCR3

4.39e-04188844ecc2364d946f97ae0212fd6739960c9fc75e4919
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC31A2 IRF8 SLC47A1 ADGRE5

4.39e-04188844d7a9fb5b021e127b8d927658a55a71098d513b5c
ToppCellHealthy_donor-NK_CD56bright|World / disease group, cell group and cell class (v2)

ADGRE5 NLRP2 ABCB1 NCR3

4.39e-041888448ee359199c61c3b5b498ac35148390db5cc1a836
ToppCell(2)_NK/T-(210)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

DIP2A IGF2R ABCB1 NCR3

4.48e-04189844fa72e87e1e8cd7cbddae7b47e19cf90d181820a7
ToppCell(2)_NK/T-(21)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

DIP2A IGF2R ABCB1 NCR3

4.48e-04189844b37ad24898a14a4a3b2d6cea2637de2471f76e20
ToppCellControl-Lymphoid-NK|Lymphoid / Disease state, Lineage and Cell class

DIP2A IGF2R IRF8 NCR3

4.57e-041908441584c68b58c7f406d9b0e8451beea3e6f8980c56
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DIP2A ADGRE5 RAB27B NCR3

4.66e-0419184404faa7d2237e45418611153294eb6f7bb690cbde
ToppCellPSB-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SLC6A4 COL4A4 ADGRB3 KCNMA1

4.66e-041918448f4637e801554e2343b974fe7794f01dd2151418
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

DIP2A ABCA2 ABCB1 NCR3

4.66e-041918446345c1aa0fd2f9f2154a44f9393bf7c72bb1f44e
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-NK|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DIP2A ADGRE5 ABCB1 NCR3

4.75e-04192844a06d5d3c2537f8d2b1dc6b6f3e88a80b5c2a1850
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_4|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

SLC6A4 COL4A4 HAL

4.82e-04818438cb94dda18010b3b05e5ab72235850483013c03a
ToppCell3'_v3-bone_marrow-Lymphocytic_NK|bone_marrow / Manually curated celltypes from each tissue

DIP2A IGF2R ADGRE5 NCR3

4.84e-04193844e790ab76c12f74a13936c231076f1e397283efb3
ToppCellICU-SEP-Lymphocyte-T_NK-NK|ICU-SEP / Disease, Lineage and Cell Type

DIP2A RAB27B ABCB1 NCR3

4.84e-04193844f110f86db305e41639087f5b1a2dff103c07adf0
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-natural_killer_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DIP2A RAB27B ABCB1 NCR3

4.94e-04194844a3a81638b55cb5fc08fe83c8b88f68d49b87e6cb
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGF2R RAB27B ABCB1 NCR3

4.94e-0419484424837a27b0041fe8c348225fa8b09b127d743603
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-natural_killer_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DIP2A RAB27B ABCB1 NCR3

4.94e-041948440abca32c3547a45cebab0bd69c1f7a0002deaa80
ToppCell10x5'-bone_marrow-Lymphocytic_NK-NK_CD56bright_CD16-|bone_marrow / Manually curated celltypes from each tissue

ABCA2 IRF8 ADGRE5 ABCB1

4.94e-041948445c58a2d1dd3c8ff77ce44d473239685e6b020909
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DIP2A ABCA2 ADGRE5 NCR3

4.94e-04194844ae5357e2a276473cde1fc8c43acaf9f69da35fd7
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-innate_lymphocytic|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DIP2A ABCA2 ADGRE5 NCR3

4.94e-041948443a0b8b5d0354c43da57bb951cd8ba878363c3de5
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FSIP2 ARHGEF38 MGARP

5.00e-0482843cefd8c6f60ef27fb8823faddca1cf8bbd636f474
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Ngfr_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FSIP2 ARHGEF38 MGARP

5.00e-04828431ed7d7f70f00d6e280cd59c54e710bb724c8b50b
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Ngfr_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FSIP2 ARHGEF38 MGARP

5.00e-0482843a5d3c5b7012d8ca7418670242d22aad3ed8c5191
ToppCellT/NK_cells-CD56bright_NK_cell|T/NK_cells / Lineage and Cell class

IRF8 ADGRE5 ABCB1 NCR3

5.04e-04195844d2c8f5c114b1864b509fad449aa4492dfc61113c
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DIP2A RAB27B ABCB1 NCR3

5.04e-04195844609732e83ab7fc3ba7dace66f5a17e46557fd6d1
ToppCell3'_v3-blood-Lymphocytic_NK-NK_CD16|blood / Manually curated celltypes from each tissue

DIP2A IRF8 ADGRE5 NCR3

5.04e-04195844789149fb52d9d16393e1649358515add60d37f2d
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DIP2A RAB27B ABCB1 NCR3

5.04e-04195844ed41e709523cc3b86b1090d4fc0938ed47cb1fc9
ToppCell10x5'v1-week_12-13-Hematopoietic-MK-early_MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NIPSNAP3A RAB27B PROS1 ABCB1

5.04e-04195844fa5fc6f605deb5cae96eec14ba4000b19f877ba6
ToppCell3'_v3-blood-Lymphocytic_NK|blood / Manually curated celltypes from each tissue

DIP2A IRF8 ADGRE5 NCR3

5.04e-04195844731a454e45c7b610e0140312bcabaea711dcc766
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIPR1 C5 RAB27B MGAM2

5.04e-04195844e87b11e3242fdbed2e7f383e6876ec375af32bd4
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

DIP2A PCNX1 ABCB1 NCR3

5.04e-041958449990440bda7fac5d00ef80444fab07459be625e1
ToppCell10x3'2.3-week_12-13-Hematopoietic-MK-early_MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NIPSNAP3A RAB27B PROS1 ABCB1

5.13e-04196844fc541e328aed28e84d5b3835169c60da0d64cddc
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCA2 ADGRE5 ABCB1 NCR3

5.13e-04196844bc4628d959d76c16981ac3b943f7c3fbbba49391
ToppCellfacs-Brain_Non-Myeloid-Cortex|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIP2A ABCA2 SEZ6L2 SLC7A11

5.13e-04196844256fe9bc0815f66a9afe11ba3507ef1372b52fd3
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_dim-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DIP2A RAB27B ABCB1 NCR3

5.13e-041968445b5cf6f70534661d694f47359b6595b4580876c3
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DIP2A PCNX1 ABCB1 NCR3

5.13e-04196844418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ComputationalGenes in the cancer module 470.

VIPR1 ABCA2 ADGRB3

3.95e-0516463MODULE_470
Diseasecongenital disorder of glycosylation Iw (implicated_via_orthology)

STT3A STT3B

6.90e-062782DOID:0080572 (implicated_via_orthology)
DiseaseEdema, Cardiac

IFT122 UBIAD1

2.07e-053782C0013608
Diseaseresponse to tenofovir

ACTL7B SLC17A4 GRIN2A

3.38e-0451783EFO_0009279
DiseaseAutistic Disorder

SLC6A4 NRXN2 KCNMA1 GRIN2A SEZ6L2

6.50e-04261785C0004352
Diseaseplatelet storage pool deficiency (implicated_via_orthology)

SLC7A11 RAB27B

7.08e-0415782DOID:2223 (implicated_via_orthology)
Diseasesleep duration, low density lipoprotein cholesterol measurement

SLC6A4 IGF2R MACO1

1.83e-0391783EFO_0004611, EFO_0005271
Diseasemalaria (is_implicated_in)

ABCB1 NCR3

1.83e-0324782DOID:12365 (is_implicated_in)
DiseaseTEMPS-A questionnaire

ADGRB3 SLC35F2

1.99e-0325782EFO_0004783
Diseasesystemic mastocytosis

ABCA2 NCR3

1.99e-0325782MONDO_0016586
Diseaseamino acid measurement

SLC6A4 KCNMA1 KIF3C C5 LRBA DNAH7 MGAM2

2.11e-03678787EFO_0005134
Diseaseretinitis pigmentosa (implicated_via_orthology)

CNGB1 AGTPBP1

2.32e-0327782DOID:10584 (implicated_via_orthology)
Diseaseattention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia

SLC35F2 GRIN2A STT3A

2.46e-03101783EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090

Protein segments in the cluster

PeptideGeneStartEntry
GLKLIYYSVGAGITD

TRBV6-6

61

A0A0A6YYG2
IYSYGKTSGLVVESG

ACTL7B

186

Q9Y614
VYGAGSSLYGGTITI

RNF20

306

Q5VTR2
STLVKGVIYGSYSVS

ADGRB3

31

O60242
VDTGNVKGYVYSSFL

ARHGEF38

626

Q9NXL2
EISFSYYLIGKGSLV

A2ML1

486

A8K2U0
IVGVSAAIYSKGYGR

ADGRE5

666

P48960
FSVQYVYGSGKKYIG

COL4A4

31

P53420
ITSVDKSYGGYEVVG

CDSN

286

Q15517
VAAGGQKGKSYYTIT

AGTPBP1

816

Q9UPW5
VYLVGTVVGGRLTYT

RANBP17

496

Q9H2T7
GDSGVGKTTFLYRYT

RAB27B

16

O00194
GYTKLVGVFHTEYGA

NIPSNAP3A

176

Q9UFN0
LSVVSIFYGTGLGVY

OR7A2P

246

Q8NGA2
LGKTFRLVGYTIQYG

IMMP1L

6

Q96LU5
YGTTLVLSGEYSIGQ

ABCB1

316

P08183
ISYFTKGEYILLGGS

IFT122

286

Q9HBG6
STVGYGDVYAKTTLG

KCNMA1

351

Q12791
FLSVAVGSTVYYQGK

NCR3

151

O14931
YRTTGGILDFYIVLG

MGAM2

1161

Q2M2H8
FVSKYLATIGIDYGV

DNAJC27

41

Q9NZQ0
VNYGLGTLVKYSFTG

ENTPD8

176

Q5MY95
IYAGVYSATFLEGII

FSIP2

3966

Q5CZC0
GTVFAYGQTGTGKTY

KIF3C

91

O14782
TEGIYGSTFLYLKFL

MACO1

21

Q8N5G2
ALKYVLYTLVGFVGF

PCNX1

1291

Q96RV3
VISFYYGGKLVGQAT

IRF8

206

Q02556
LISYGYVGGTVLRIK

OR2W6P

221

Q8NHA6
VGIFYGTGVFSYTRL

OR3A4P

251

P47883
GYKAIFVTVDTPYLG

HAO1

151

Q9UJM8
GTTYIFGKGGALITY

NRXN2

1136

Q9P2S2
IFAIYQLGLGYKGTF

LRBA

376

P50851
SYTVVLYGPAGLGKT

NLRP2

206

Q9NX02
YLGGIIYLVFIGSTI

AQP7

266

O14520
FLLCGVLYVVYSTGG

OLFML1

321

Q6UWY5
CVVSLFYGTGLGVYL

OR7D4

246

Q8NG98
TTYIFGKGGALITYT

NRXN2

91

P58401
SVVTLFYGTGFGVYL

OR7C1

246

O76099
VLKSYIGLGHIYSGT

CLCN6

506

P51797
TVVYGITTGFGKFAR

HAL

161

P42357
SLAVLGGKLYVSGGY

KLHL21

506

Q9UJP4
IFLGVVLGSAVGYYL

SLC31A2

121

O15432
KYLYIAVTVIESTGG

C5

321

P01031
GTIYDYQFVTEGIGK

DNAH7

1911

Q8WXX0
GSKYFALYEVAGVGI

ABCA2

861

Q9BZC7
GKIAVISGVGTRNYY

ELP3

516

Q9H9T3
ATVLVGEYLSISFYG

MS4A8

91

Q9BY19
VVGVTVSAGGYYAYK

MGARP

51

Q8TDB4
LGLSGLVGTVTRTYY

HEPHL1

16

Q6MZM0
GTAYYGLLGITKNVF

DIP2A

756

Q14689
LIYGPFGTGKTYTLA

HELZ2

541

Q9BYK8
TLFIFGVTKYIAGPY

PSG4

201

Q00888
IPSGYVAGIFGAKYV

SLC17A4

126

Q9Y2C5
ISGRYVSIGKFGTCY

SACS

3416

Q9NZJ4
ILFTAGYLSLFGYTK

CYP8B1

176

Q9UNU6
VVSLFYGTGLGVYLS

OR7C2

246

O60412
VLTLQSGTYGVYEIG

SLC8B1

371

Q6J4K2
SVVSLFYGTVIGLYL

OR1E1

246

P30953
SVVALFYGTTIGVYL

OR1M1

246

Q8NGA1
VVLGKGTYGIVYAGR

MAP3K15

656

Q6ZN16
TYIGGVTFSGSLIAY

NNT

746

Q13423
VQGTQVYVFLTKGGY

HPX

321

P02790
VYVFLTKGGYTLVSG

HPX

326

P02790
GVIGDKVVVTYSKGY

IGF2R

2066

P11717
GIGGITTSTQFYYKL

ERVW-1

336

Q9UQF0
PGSGVTGYLKVTIYA

FER1L5

276

A0AVI2
TGYLKVTIYALGVGD

FER1L5

281

A0AVI2
SIVLLFYGAGLGVYI

OR7G2

246

Q8NG99
FYGAGLGVYISSVVT

OR7G2

251

Q8NG99
IVVSLFYGTGFGVYL

OR7G3

246

Q8NG95
SYVLVIFGGLTGYSS

STT3A

576

P46977
VTQTYGAAAGKGTYV

WIPI2

396

Q9Y4P8
GEVYGVVKAYTTRVG

ADSS2

291

P30520
VIVLGSGVYIYYTKL

SEZ6L2

856

Q6UXD5
GYKFSGLYILSFTVI

SLC35F2

311

Q8IXU6
LVTVEKGSYYPGSGI

PROS1

476

P07225
KVGAIVNTIGYYVVG

SLC47A1

406

Q96FL8
YYFAVKTLITIGGLP

CNGB1

836

Q14028
GTTIKKSGGHYTYIL

SLC7A11

101

Q9UPY5
GAFTYLVGVYVALIG

TMEM86A

141

Q8N2M4
SVKTGYTIGYGLSLA

VIPR1

141

P32241
AVLTYVGYGVLTLFG

SPTLC2

71

O15270
AGAVFLSVIYLTYTG

STT3B

361

Q8TCJ2
YTLLGIYTGSGVLAV

UNC93A

201

Q86WB7
SFLYTGGIGFKYVAL

UBIAD1

171

Q9Y5Z9
GSLVTLTFGGAYVVK

SLC6A4

476

P31645
LAFTGVAGYITYLSI

SLC66A2

151

Q8N2U9
DGYVVKETIGVGSYS

RPS6KA1

416

Q15418
KLVTIGSGYIFATTG

GRIN2A

746

Q12879