Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
HumanPhenoPolyphagia

CHD8 CTNNB1 MBD5 SKI SLC3A1

2.01e-0578235HP:0002591
MousePhenoincreased dendritic spine number

KIF4A KIF4B

3.31e-053472MP:0021019
MousePhenoabnormal telencephalon morphology

FZD9 POMGNT2 ZIC5 HAP1 ARFGEF2 KIF4A KIF4B PAX3 CTNNB1 SKI POMK

6.01e-058124711MP:0000787
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TANC2 SPHK2 POMGNT2 EIF4ENIF1 ESYT1 ARFGEF2 ADGRL1 CHD8 PANX1 BCAM MBD5 BRAT1

5.97e-071105631235748872
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

FOXP4 POMGNT2 ESYT1 FRMPD1 KIF4A ANKRD28 PAX3 CTNNB1 CBFA2T3 SKI

3.07e-06857631025609649
Pubmed

KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.

KIF4A KIF4B

3.23e-06263236482480
Pubmed

Whole genome expression microarray reveals novel roles for Kif4 in monocyte/macrophage cells.

KIF4A KIF4B

3.23e-06263231486502
Pubmed

Pannexin 1 binds β-catenin to modulate melanoma cell growth and metabolism.

PANX1 CTNNB1

3.23e-06263233647315
Pubmed

Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization.

KIF4A KIF4B

3.23e-06263210773663
Pubmed

The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential.

KIF4A KIF4B

3.23e-06263230081192
Pubmed

Missense Pathogenic variants in KIF4A Affect Dental Morphogenesis Resulting in X-linked Taurodontism, Microdontia and Dens-Invaginatus.

KIF4A KIF4B

3.23e-06263231616463
Pubmed

Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis.

KIF4A KIF4B

3.23e-06263231067151
Pubmed

Kif4 regulates the expression of VEGFR1 through the PI3K/Akt signaling pathway in RAW264.7 monocytes/macrophages.

KIF4A KIF4B

3.23e-06263228350061
Pubmed

Cellular motor protein KIF-4 associates with retroviral Gag.

KIF4A KIF4B

3.23e-06263210559369
Pubmed

Kif4 interacts with EB1 and stabilizes microtubules downstream of Rho-mDia in migrating fibroblasts.

KIF4A KIF4B

3.23e-06263224658398
Pubmed

KIF4 regulates midzone length during cytokinesis.

KIF4A KIF4B

3.23e-06263221565503
Pubmed

A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally.

KIF4A KIF4B

3.23e-0626327929562
Pubmed

Structural basis for the ATP-induced isomerization of kinesin.

KIF4A KIF4B

3.23e-06263223500491
Pubmed

A novel beta-catenin-binding protein inhibits beta-catenin-dependent Tcf activation and axis formation.

CHD8 CTNNB1

3.23e-06263210921920
Pubmed

Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein.

KIF4A KIF4B

3.23e-0626329658142
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

TRERF1 FOXP4 RBM10 KIF4A CHD8 SKI

9.31e-0626863633640491
Pubmed

Tumor formation via loss of a molecular motor protein.

KIF4A KIF4B

9.68e-06363216890532
Pubmed

KIF4 mediates anterograde translocation and positioning of ribosomal constituents to axons.

KIF4A KIF4B

9.68e-06363219158085
Pubmed

Lymphoid enhancer factor-1 mediates loading of Pax3 to a promoter harbouring lymphoid enhancer factor-1 binding sites resulting in enhancement of transcription.

PAX3 CTNNB1

9.68e-06363220006729
Pubmed

Identification of the human homologue of mouse KIF4, a kinesin superfamily motor protein.

KIF4A KIF4B

9.68e-06363210978527
Pubmed

CHD8 is an ATP-dependent chromatin remodeling factor that regulates beta-catenin target genes.

CHD8 CTNNB1

9.68e-06363218378692
Pubmed

KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity.

KIF4A KIF4B

9.68e-06363216630823
Pubmed

β-Catenin/Tcf7l2-dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer.

ZIC5 CTNNB1

9.68e-06363231392276
Pubmed

Wild-type BRCA1, but not mutated BRCA1, regulates the expression of the nuclear form of beta-catenin.

CHD8 CTNNB1

9.68e-06363220215423
Pubmed

SGK196 is a glycosylation-specific O-mannose kinase required for dystroglycan function.

POMGNT2 POMK

9.68e-06363223929950
Pubmed

CircKIF4A enhances osteosarcoma proliferation and metastasis by sponging MiR-515-5p and upregulating SLC7A11.

KIF4A KIF4B

9.68e-06363235579738
Pubmed

Enhancement of β-catenin activity by BIG1 plus BIG2 via Arf activation and cAMP signals.

ARFGEF2 CTNNB1

9.68e-06363227162341
Pubmed

Kinesin KIF4 regulates intracellular trafficking and stability of the human immunodeficiency virus type 1 Gag polyprotein.

KIF4A KIF4B

1.93e-05463218684836
Pubmed

Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation.

APLP1 CPEB1

1.93e-05463216314516
Pubmed

Association of THADA, FOXP4, GPRC6A/RFX6 genes and 8q24 risk alleles with prostate cancer in Northern Chinese men.

FOXP4 RFX6

1.93e-05463226537068
Pubmed

Replication and fine mapping for association of the C2orf43, FOXP4, GPRC6A and RFX6 genes with prostate cancer in the Chinese population.

FOXP4 RFX6

1.93e-05463222662242
Pubmed

Beta catenin-independent activation of MyoD in presomitic mesoderm requires PKC and depends on Pax3 transcriptional activity.

PAX3 CTNNB1

1.93e-05463217275805
Pubmed

Kif4 Is Essential for Mouse Oocyte Meiosis.

KIF4A KIF4B

1.93e-05463228125646
Pubmed

Tbx4 and tbx5 acting in connective tissue are required for limb muscle and tendon patterning.

PAX3 CTNNB1

3.22e-05563220152185
Pubmed

Frizzled-9 is activated by Wnt-2 and functions in Wnt/beta -catenin signaling.

FZD9 CTNNB1

3.22e-05563212138115
Pubmed

Myeloid translocation gene family members associate with T-cell factors (TCFs) and influence TCF-dependent transcription.

CTNNB1 CBFA2T3

3.22e-05563218039847
Pubmed

Nuclear localization of Duplin, a beta-catenin-binding protein, is essential for its inhibitory activity on the Wnt signaling pathway.

CHD8 CTNNB1

3.22e-05563211744694
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

DDX47 KIF4A KIF4B CTNNB1 TOX2

3.44e-0520363522083510
Pubmed

Human transcription factor protein interaction networks.

TRERF1 FOXP4 NOL4L EIF4ENIF1 RBM10 ANKRD28 PUM3 PPIL2 CHD8 SKI CPEB1

4.68e-051429631135140242
Pubmed

Genetic and molecular control of folate-homocysteine metabolism in mutant mice.

PAX3 SKI

4.82e-05663212016514
Pubmed

Restricted Pax3 Deletion within the Neural Tube Results in Congenital Hydrocephalus.

PAX3 CTNNB1

4.82e-05663226949601
Pubmed

Genetic interaction of Pax3 mutation and canonical Wnt signaling modulates neural tube defects and neural crest abnormalities.

PAX3 CTNNB1

4.82e-05663234490995
Pubmed

Regulation of Neural Circuit Development by Cadherin-11 Provides Implications for Autism.

CTNNB1 CDH8

4.82e-05663234135003
Pubmed

Domains of Brn-2 that mediate homodimerization and interaction with general and melanocytic transcription factors.

GTF2B PAX3

4.82e-05663211029584
Pubmed

Histone H1 recruitment by CHD8 is essential for suppression of the Wnt-β-catenin signaling pathway.

CHD8 CTNNB1

4.82e-05663222083958
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

GTF2B FOXP4 KIF4A KIF4B PPIL2 CHD8

5.67e-0537063622922362
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TRERF1 TANC2 HECW1 KIF4A ANKRD28 KIF4B CHD8 CTNNB1 TMEM132B

5.71e-0596363928671696
Pubmed

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.

TANC2 FOXP4 RBM10 ANKRD28 ADGRL1 PPIL2

6.38e-0537863634315543
Pubmed

Regulation of cell protrusions by small GTPases during fusion of the neural folds.

PAX3 CTNNB1

6.74e-05763227114066
Pubmed

Early embryonic death in mice lacking the beta-catenin-binding protein Duplin.

CHD8 CTNNB1

6.74e-05763215367660
Pubmed

Genetic mapping in the mouse of Kif4, a gene encoding a kinesin-like motor protein.

KIF4A KIF4B

6.74e-0576329196009
Pubmed

The Wnt serpentine receptor Frizzled-9 regulates new bone formation in fracture healing.

FZD9 CTNNB1

6.74e-05763224391920
Pubmed

The physical association and phosphorylation of Cdc25C protein phosphatase by Prk.

PLK2 CHEK1

6.74e-05763210557092
Pubmed

Unusual chromatin status and organization of the inactive X chromosome in murine trophoblast giant cells.

KIF4A KIF4B

6.74e-05763223362347
Pubmed

Kinesin family in murine central nervous system.

KIF4A KIF4B

6.74e-0576321447303
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

DDX47 TANC2 RBM10 ARFGEF2 KIF4A CHD8 CHEK1

8.72e-0558263720467437
Pubmed

Pax3 lineage-specific deletion of Gpr161 is associated with spinal neural tube and craniofacial malformations during embryonic development.

PAX3 CTNNB1

8.98e-05863237885410
Pubmed

Embryonic and fetal limb myogenic cells are derived from developmentally distinct progenitors and have different requirements for beta-catenin.

PAX3 CTNNB1

8.98e-05863219346403
Pubmed

Pax3 functions at a nodal point in melanocyte stem cell differentiation.

PAX3 CTNNB1

8.98e-05863215729346
Pubmed

The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes neural crest cell fate.

PAX3 CTNNB1

8.98e-05863211684651
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TRERF1 NOL4L EIF4ENIF1 ANKRD28 CHD8 CHEK1

1.11e-0441863634709266
Pubmed

The autism-associated protein CHD8 is required for cerebellar development and motor function.

CHD8 CDH8

1.15e-04963233826902
Pubmed

Transcriptional analyses of two mouse models of spina bifida.

PAX3 SKI

1.15e-04963223024056
Pubmed

Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells.

FZD9 CTNNB1

1.15e-04963219038973
Pubmed

A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals.

FZD9 CTNNB1

1.15e-0496329707618
Pubmed

Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherins.

CTNNB1 CDH8

1.44e-041063210861224
Pubmed

Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass.

KIF4A KIF4B

1.44e-041063229101321
Pubmed

Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.

FOXP4 RFX6

1.44e-041063220676098
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

DDX47 ESYT1 RBM10 PUM3 CHD8 CTNNB1

1.46e-0444063634244565
Pubmed

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

UGGT1 KIF4A KIF4B CHD8 SLC3A1

1.67e-0428463529459677
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DDX47 TANC2 FOXP4 EIF4ENIF1 ANKRD28 CHD8 LRRC8B CHEK1 SKI

1.74e-04111663931753913
Pubmed

Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells.

FZD9 CTNNB1

1.76e-041163224860427
Pubmed

Characterization of nuclear factors modulating the apolipoprotein D promoter during growth arrest: implication of PARP-1, APEX-1 and ERK1/2 catalytic activities.

KIF4A KIF4B

1.76e-041163220493910
Pubmed

Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference.

KIF4A KIF4B

1.76e-041163215843429
Pubmed

Precise spatial restriction of BMP signaling in developing joints is perturbed upon loss of embryo movement.

PAX3 CTNNB1

1.76e-041163229467244
Pubmed

Phenotypic annotation of the mouse X chromosome.

RBM10 KIF4A KIF4B

1.89e-046163320548051
Pubmed

The loop-tail mouse model displays open and closed caudal neural tube defects.

PAX3 CTNNB1

2.11e-041263237589570
Pubmed

Met signaling is required for recruitment of motor neurons to PEA3-positive motor pools.

PAX3 CDH8

2.49e-041363212948444
Pubmed

Organization of motor pools depends on the combined function of N-cadherin and type II cadherins.

CTNNB1 CDH8

2.49e-041363231235635
Pubmed

Wnt5a is a transcriptional target of Dlx homeogenes and promotes differentiation of interneuron progenitors in vitro and in vivo.

FZD9 CTNNB1

2.90e-041463221325536
Pubmed

The orphan GPCR, Gpr161, regulates the retinoic acid and canonical Wnt pathways during neurulation.

PAX3 CTNNB1

3.34e-041563225753732
Pubmed

SOXF factors regulate murine satellite cell self-renewal and function through inhibition of β-catenin activity.

PAX3 CTNNB1

3.34e-041563229882512
Pubmed

Hoxc8 initiates an ectopic mammary program by regulating Fgf10 and Tbx3 expression and Wnt/β-catenin signaling.

PAX3 CTNNB1

3.34e-041563226459221
Pubmed

Molecular properties and chromosomal location of cadherin-8.

CTNNB1 CDH8

3.81e-04166329521872
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

DDX47 ESYT1 RBM10 KIF4A PUM3 PPIL2 CTNNB1 BRAT1

4.03e-0498963836424410
Pubmed

Colonization of the satellite cell niche by skeletal muscle progenitor cells depends on Notch signals.

PAX3 CTNNB1

4.32e-041763222940113
Pubmed

Constitutive metanephric mesenchyme-specific expression of interferon-gamma causes renal dysplasia by regulating Sall1 expression.

PAX3 CTNNB1

4.32e-041763229771971
Pubmed

Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development.

PAX3 CTNNB1

4.32e-041763212464179
Pubmed

Interaction network of human early embryonic transcription factors.

TRERF1 FOXP4 CHD8 CTNNB1 SKI

4.43e-0435163538297188
Pubmed

Lis1-Nde1-dependent neuronal fate control determines cerebral cortical size and lamination.

PAX3 CTNNB1

4.85e-041863218469343
Pubmed

Targeted disruption of the DM domain containing transcription factor Dmrt2 reveals an essential role in somite patterning.

PAX3 CTNNB1

4.85e-041863216387292
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

GTF2B CPAMD8 NOL4L AOPEP UGGT1 CHEK1 BCAM CBFA2T3 BRAT1

5.13e-04129363915342556
Pubmed

The role of Lrp6-mediated Wnt/β-catenin signaling in the development and intervention of spinal neural tube defects in mice.

PAX3 CTNNB1

5.41e-041963235514236
Pubmed

α5β1 integrin-mediated adhesion to fibronectin is required for axis elongation and somitogenesis in mice.

PAX3 CTNNB1

5.41e-041963221799763
Pubmed

hnRNPH1 recruits PTBP2 and SRSF3 to modulate alternative splicing in germ cells.

CTNNB1 CPEB1

5.41e-041963235739118
Pubmed

Probing transcription-specific outputs of β-catenin in vivo.

PAX3 CTNNB1

5.41e-041963222190459
Pubmed

Sfrp1 and Sfrp2 regulate anteroposterior axis elongation and somite segmentation during mouse embryogenesis.

PAX3 CTNNB1

6.01e-042063216467359
Pubmed

beta-Catenin regulates intercellular signalling networks and cell-type specific transcription in the developing mouse midbrain-rhombomere 1 region.

PAX3 CTNNB1

6.01e-042063220532162
CoexpressionGSE42021_TCONV_PLN_VS_CD24LO_TCONV_THYMUS_DN

EIF4ENIF1 FAM53A ESYT1 KIF4A PUM3 SKI CPEB1

4.17e-07200617M9606
CoexpressionGSE17721_CTRL_VS_PAM3CSK4_24H_BMDC_DN

GTF2B AOPEP FAM53A PUM3 PANX1 CPEB1

7.17e-06200616M3752
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#1

FOXP4 ZIC5 HAP1 LRRC8B TOX2

3.48e-05127625Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K1
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_1000

GTF2B CHD8 CHEK1 TOX2 CPEB1

5.18e-05138625gudmap_developingGonad_e12.5_epididymis_k5_1000
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POMGNT2 AOPEP TONSL ARFGEF2 ANKRD28

4.03e-06168635b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCellCV-Mild-6|Mild / Virus stimulation, Condition and Cluster

FAM53A ADGRL1 CHD8 MBD5 ALPK2

4.92e-06175635c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 ADGRL1 RFX6 DNAH9 CPEB1

5.35e-0617863530ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCellcontrol-immature_Neutrophil|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TRERF1 TANC2 KIF4A CHEK1 POMK

8.54e-06196635e34fd3e7a5b1c22a81fd3208e6d58bdb846d51c4
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal|GW09 / Sample Type, Dataset, Time_group, and Cell type.

FOXP4 PLK2 PHYHIP APLP1 RPS6KL1

9.41e-0620063509fd3cb31bcc02444f1045f01fe39bce09359d35
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP4 MXRA5 POMGNT2 OR14J1

5.61e-05147634f703cb0330304799d16e457215269c7732c9d5d5
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A9 NOL4L HAP1 PHYHIP

7.42e-0515863412661763d1c309106801cb710c04cd2b62d16cba
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A9 NOL4L HAP1 PHYHIP

7.42e-051586340792c39e6fc0745095af7812de2d50949540d60f
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A9 NOL4L HAP1 PHYHIP

7.42e-05158634e7db50d6dfaf7280a73a0d5b5aa4f43ea2762d72
ToppCell390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

KIF4A APLP1 CHEK1 RPS6KL1

7.61e-051596340fbfdb18b7ed4bde077add13f2b3636e144b254f
ToppCellcritical-Epithelial-unknown_epithelial|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

GTF2B PLK2 HAP1 PHYHIP

7.98e-05161634594cf3245ec065a7685db81cd8ba2cee8d42caac
ToppCellCV-Mild-6|CV / Virus stimulation, Condition and Cluster

TRERF1 FAM53A MBD5 ALPK2

9.20e-05167634cf2ed0b6d17a16f9a2318879ce8856d5983ad3cf
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FZD9 FOXP4 HAP1 BCAM

9.63e-0516963405e12524d68d409fed386ffad233305683b4575b
ToppCell5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HAP1 AOPEP BCAM CBFA2T3

1.03e-04172634bd01b39a5699824ab14827cc9dc98e547d65b160
ToppCellNS-critical-d_16-33-Epithelial-unknown_epithelial|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GTF2B PLK2 HAP1 PHYHIP

1.03e-04172634c0b5e4889aef2f168d9f6db19a63b24bfd249316
ToppCell5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HAP1 AOPEP BCAM CBFA2T3

1.08e-04174634911eac6f6ec1e5e85348a7fe774243498388a810
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRERF1 POMGNT2 APLP1 MBD5

1.10e-041756341d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRERF1 POMGNT2 APLP1 MBD5

1.10e-04175634427a7ee92fe16a90625946492062d37aa0f7235b
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EIF4ENIF1 ANKRD28 PANX1 CHEK1

1.13e-041766341510cdfcfb46ce1196a1220c07fb5f3986c81b78
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TANC2 CPAMD8 APLP1 BCAM

1.13e-0417663452af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UGGT1 SLC39A6 RFX6 CDH8

1.18e-04178634fcbbcc44271515de1969b4732b6441c012693d5f
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAP1 APLP1 RFX6 DNAH9

1.28e-04182634398ce074a04f6482470b488f1affae4af7d2ec58
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 BCAM CBFA2T3 TOX2

1.31e-04183634709a486154b3157427deb3b8886b63ac39ea42dd
ToppCelldroplet-Liver-nan-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 BCAM CBFA2T3 TOX2

1.31e-04183634dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCell3'_v3-blood-Lymphocytic_T_CD4/8-lo|blood / Manually curated celltypes from each tissue

ESYT1 KIF4A CHEK1 TOX2

1.36e-04185634df85ff34b796b403f2d0741771e9592e03657f6a
ToppCelldroplet-Lung-nan-21m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 CIDEB CTNNB1 SKI

1.39e-041866348f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCelldroplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 CIDEB CTNNB1 SKI

1.39e-04186634f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCellSubstantia_nigra-Neuronal|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FOXP4 HECW1 PHYHIP CDH8

1.39e-041866343f889083fcffe516388e9b03a5e23af2010ced33
ToppCelldroplet-Pancreas|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAP1 APLP1 RFX6 CPEB1

1.42e-041876345f4df092452d8672bda4059c794e099ba3f5a8fa
ToppCelldroplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TONSL KIF4A CHEK1 ALPK2

1.45e-041886340ec2a1b0505501ba18f10a5fce68c306a6292419
ToppCell3'_v3-blood-Lymphocytic_T_CD4/8-lo-Cycling_T|blood / Manually curated celltypes from each tissue

ESYT1 KIF4A CHEK1 TOX2

1.45e-04188634714ccbcf826f26d39757931a3b8abbd952f4cddc
ToppCellfacs-Kidney-nan-24m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 AOPEP BCAM CBFA2T3

1.48e-041896349d02a824bba59ea0660439f0510d843568e9d8c3
ToppCellfacs-Kidney-nan-24m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 AOPEP BCAM CBFA2T3

1.48e-041896345f8d4b61296c71b32362432a9ce4c1c3aaeb278d
ToppCellfacs-Kidney-nan-24m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 AOPEP BCAM CBFA2T3

1.48e-0418963418f82764b32496e54d1a604a531b261651c5e110
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAP1 TOX2 TMEM132B CDH8

1.48e-04189634fcc3713e8200d51074f709f3360fb36efb0a639f
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAP1 ADGRL1 APLP1 RFX6

1.54e-04191634a251b134f67a0a1ef3a42f50042f128a17f20b22
ToppCellfacs-Pancreas|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HAP1 APLP1 RFX6 CPEB1

1.54e-04191634d48e5f67d384226add7d7fb2a124954136e09a82
ToppCellfacs-Kidney-nan-18m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 AOPEP BCAM CBFA2T3

1.57e-04192634777e386a17bba9ec450bb9d64d8a9ab98d9a63ff
ToppCellfacs-Kidney-nan-18m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 AOPEP BCAM CBFA2T3

1.57e-0419263460a2409546525a40a5658e0f9d6a50c37f28bb96
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_3|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PLK2 MXRA5 APLP1 CDH8

1.57e-04192634d88753b200d9c8da6716222d697ddf0a1548d6c8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 MXRA5 SLC39A6 BCAM

1.57e-04192634d5ec4cdb15620a5abfc83577353501186c2bc86a
ToppCellfacs-Kidney-nan-18m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 AOPEP BCAM CBFA2T3

1.57e-041926340f9db6091b373334b9beabe0e5782bf2bc54690b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 MXRA5 SLC39A6 BCAM

1.57e-041926349e031bf93eb8757fdd0cc22f01b44e48f85532d5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 MXRA5 SLC39A6 BCAM

1.57e-041926343d777d07878269b87ec7e1f06489cae7c989d633
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

HECW1 HAP1 PHYHIP CDH8

1.57e-041926344c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellFetal_brain-fetalBrain_Zhong_nature|Fetal_brain / Sample Type, Dataset, Time_group, and Cell type.

DDX47 NOL4L ADGRL1 PUM3

1.60e-041936341553c856f3b71c1b0a78ec8d59c7948144d9c5bb
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 CPAMD8 AOPEP SH2D3A

1.60e-04193634f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 CPAMD8 AOPEP SH2D3A

1.60e-0419363442df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 MXRA5 SLC39A6 BCAM

1.60e-041936345da60321bcf761913eb30779b6d8b1e933c5e51e
ToppCellfacs-Marrow-KLS-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POMGNT2 SLC39A6 PUM3 CHEK1

1.64e-04194634c9ebdcc2ea600975dade68a41fa65d1f8a5a5926
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD9 PLK2 POMGNT2 CBFA2T3

1.64e-041946340797245ebfa389a6f66874cb0f11297f1456e600
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD9 PLK2 POMGNT2 CBFA2T3

1.64e-041946340241b4b88d6210b4c1b8aa99db17115b18142f01
ToppCellControl-Lymphoid-T|Lymphoid / Disease state, Lineage and Cell class

TRERF1 ANKRD28 SKI TOX2

1.67e-041956346687e579582d7a239bee80846de0cf827a6f6a62
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 MXRA5 SLC39A6 BCAM

1.67e-041956340ac7762197cdd8d643f87148573a8df6e936c1b0
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

TANC2 AOPEP ADGRL1 ALPK2

1.74e-0419763415b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

TANC2 AOPEP ADGRL1 ALPK2

1.74e-04197634a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRERF1 PLK2 PAX3 CDH8

1.77e-0419863428ada093cec552262731194a04a4b9ff93186c3b
ToppCelldistal-Endothelial-Artery-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CPAMD8 PLK2 BCAM TOX2

1.77e-04198634f284f59f4ebe55ee132eddfaa2f5d9ecb059654f
ToppCelldistal-1-Endothelial-Artery|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CPAMD8 PLK2 BCAM TOX2

1.80e-04199634fd71d08f6de790a29c880d50d2ed0881952d7791
ToppCelldistal-Endothelial-Artery|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CPAMD8 PLK2 BCAM TOX2

1.80e-04199634b6e9aaac047d4b64b9d97f5e174e89a424d8b36d
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal|GW09 / Sample Type, Dataset, Time_group, and Cell type.

FOXP4 PLK2 PHYHIP APLP1

1.84e-04200634e9eb348a66011d8aace4331f84690ae27cb0d061
ToppCellBiopsy_IPF-Epithelial-Proliferating_Epithelial_cells|Biopsy_IPF / Sample group, Lineage and Cell type

TONSL KIF4A CHEK1 BCAM

1.84e-0420063463c5402f050fdb12abab3c8b7f33d4914ae26b9b
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal-Neurons|GW09 / Sample Type, Dataset, Time_group, and Cell type.

FOXP4 PHYHIP APLP1 RPS6KL1

1.84e-04200634ddac952ad1d46021c2d17d816de9bc31730a0941
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CPAMD8 APLP1 BCAM TOX2

1.84e-042006347547d6339f9380d031cfd2cce21ac9a12491e085
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Cortical_neuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

FOXP4 PLK2 PHYHIP APLP1

1.84e-0420063444bc4d6616fc8d0ad8498e56125939034e8cff01
DiseaseIniencephaly

ZIC5 PAX3 SKI

2.65e-0528613C0152234
DiseaseTethered Cord Syndrome

ZIC5 PAX3 SKI

2.65e-0528613C0080218
DiseaseSpinal Cord Myelodysplasia

ZIC5 PAX3 SKI

2.65e-0528613C0344479
DiseaseExencephaly

ZIC5 PAX3 SKI

2.65e-0528613C0266453
DiseaseNeurenteric Cyst

ZIC5 PAX3 SKI

2.65e-0528613C0027806
DiseaseAcrania

ZIC5 PAX3 SKI

2.65e-0528613C0702169
DiseaseDiastematomyelia

ZIC5 PAX3 SKI

2.65e-0528613C0011999
DiseaseCraniorachischisis

ZIC5 PAX3 SKI

2.96e-0529613C0152426
DiseaseNeural Tube Defects

ZIC5 PAX3 SKI

3.28e-0530613C0027794
Diseaseattention deficit hyperactivity disorder, autism spectrum disorder, intelligence

SLC6A9 PLK2 ARFGEF2 CTNNB1 CDH8 CPEB1

1.72e-04398616EFO_0003756, EFO_0003888, EFO_0004337
DiseaseCraniofacial Abnormalities

ZIC5 PAX3 CTNNB1 SKI

3.10e-04156614C0376634
DiseaseMalignant neoplasm of breast

TRERF1 FOXP4 FRMPD1 SH2D3A ARFGEF2 SLC39A6 CHEK1 CTNNB1 DNAH9

3.43e-041074619C0006142
Diseasedystonia (is_implicated_in)

AOPEP SHQ1

3.76e-0414612DOID:543 (is_implicated_in)
DiseaseMUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2K

POMGNT2 POMK

3.76e-0414612C1836373
Diseasealpha-Dystroglycanopathies

POMGNT2 POMK

3.76e-0414612C2936406
DiseaseMuscle eye brain disease

POMGNT2 POMK

3.76e-0414612C0457133
DiseaseFukuyama Type Congenital Muscular Dystrophy

POMGNT2 POMK

3.76e-0414612C0410174
DiseaseMuscular Dystrophy-Dystroglycanopathy (Congenital with Brain and Eye Anomalies) Type A, 1

POMGNT2 POMK

3.76e-0414612C4284790
DiseaseWalker-Warburg congenital muscular dystrophy

POMGNT2 POMK

4.34e-0415612C0265221
Diseasecognitive function measurement, self reported educational attainment

TANC2 NOL4L ARFGEF2 CDH8 CPEB1

8.39e-04355615EFO_0004784, EFO_0008354
DiseaseAlzheimer disease, APOE carrier status

ZIC5 PPIL2 PAX3

1.11e-0398613EFO_0007659, MONDO_0004975
DiseaseMuscular Dystrophies, Limb-Girdle

POMGNT2 POMK

2.00e-0332612C0686353

Protein segments in the cluster

PeptideGeneStartEntry
LGFTAIPLHGQMSQS

DDX47

286

Q9H0S4
GMTNLLDIPGLSSLS

ESYT1

276

Q9BSJ8
VTAMGQLSSQGLHAP

BRAT1

566

Q6PJG6
FLSKGAGHTNMPNLL

CHD8

1071

Q9HCK8
ALMQGGSTGSLSLHN

CHD8

2431

Q9HCK8
DHMLLNSQLLGTPGS

CHEK1

351

O14757
QTGMTLILGPHQDGT

ALPK2

426

Q86TB3
NSTPTLNRGTMGNHL

ADGRL1

1171

O94910
AQGRSGHELGMTPLQ

ARFGEF2

541

Q9Y6D5
CSSQGLILHGSGMLL

APLP1

181

P51693
GNGQTPLMLSVLNGH

ANKRD28

651

O15084
NLPEEQLGALLAGMH

COMMD5

76

Q9GZQ3
PHIMFLSQSILTGGN

AOPEP

456

Q8N6M6
NLNPHSTMDSILGAL

RBM10

306

P98175
PNLSHTGRGILSMAN

PPIL2

356

Q13356
PLTGQMELSQIAGHL

RFX6

626

Q8HWS3
MNAIASLAATGLHPG

PUM3

526

Q15397
GNLGMITLIGLSSHL

OR8G5

76

Q8NG78
GGMQALGLHLTDPSQ

CTNNB1

361

P35222
LLHSMPSAQGGSAAE

HECW1

566

Q76N89
GLSGLMHAAINFSIP

OR14J1

151

Q9UGF5
MLNPGSASSLLPLSH

FOXP4

591

Q8IVH2
FHGNTSVMLPNLGSR

POMGNT2

96

Q8NAT1
SSGQGIDPMLLLTNL

PANX1

356

Q96RD7
LQTGNHSNGPTDLSM

NOL4L

356

Q96MY1
LLMNGSSHSPTAING

CBFA2T3

126

O75081
LLGKNSLMNLSPHVG

LRRC8B

731

Q6P9F7
SLMNLSPHVGELSNL

LRRC8B

736

Q6P9F7
NGLSPQVMGLLTNHG

PAX3

386

P23760
RMPNLLGHTSQGEAA

FZD9

56

O00144
LISGHSQGNSLLCMP

FRMPD1

166

Q5SYB0
SIIGDVMGPTLNHLN

CPAMD8

1121

Q8IZJ3
ALEASGLGPSHLDMN

HAP1

611

P54257
LSQSGMALGNSLHPN

MBD5

796

Q9P267
LLQDSLGGNSHTLMI

KIF4A

296

O95239
LLQDSLGGNSHTLMI

KIF4B

296

Q2VIQ3
SVLSMLHNPLGNVLG

CPEB1

126

Q9BZB8
LTQSLHLTMSGAPAG

DNAH9

1856

Q9NYC9
QVLMSGSPLELNSLG

CDH8

36

P55286
SHSGSEQPEQTGLLM

BCAM

596

P50895
AQLLLLGSAGPTMEN

METTL17

71

Q9H7H0
GNLGMITLIGLSSHL

OR8G3P

41

P0DMU2
GVQLVAGMSLSLQPH

TMEM132B

661

Q14DG7
PGQHFEGLNMLTALL

SHQ1

81

Q6PI26
ESTLLNLHNMISGLP

SLC3A1

601

Q07837
SPHGMLANGSRGDLL

TANC2

1921

Q9HCD6
LGTLGEISGHQLMSL

PHYHIP

296

Q92561
NDLDALPLVNHSSGM

POMK

226

Q9H5K3
LEQFHLSSMSSLGGP

SKI

21

P12755
LTSHGMGIQVPLNAT

SLC39A6

271

Q13433
GMDLSHLQGISGPIL

EIF4ENIF1

856

Q9NRA8
LQGLGHMLLGISSTL

CIDEB

186

Q9UHD4
DPDGHSMSLPLLQGL

C11orf42

311

Q8N5U0
LQAQMHPGIGTLLTG

SPHK2

631

Q9NRA0
QNPLLSDGDLSTMIG

GTF2B

71

Q00403
NMGVSSGLELLTLPH

SH2D3A

341

Q9BRG2
SSNHLGPEGLRQLAM

TONSL

1106

Q96HA7
NSGLLPQLMAQHSLA

SLC6A9

66

P48067
ELLTGMALSQSHPSG

RPS6KL1

476

Q9Y6S9
NMLAQDSHLLSGQLP

TOX2

131

Q96NM4
GVLFNNGAHMSLLPD

PLK2

526

Q9NYY3
LQPGDSALFINGLHM

UGGT1

386

Q9NYU2
LGPEHMAQASTLGLS

ZIC5

91

Q96T25
RPLLSPSGIHLNNMG

TRERF1

451

Q96PN7
FLPGLSAAAHTMGLQ

FAM53A

71

Q6NSI3
TLQGGNMLEGDPTHS

MXRA5

1066

Q9NR99