Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	retinoic acid binding	UGT1A8 UGT1A7 UGT1A9	1.69e-04	28	77	3	GO:0001972
GeneOntologyMolecularFunction	glucuronosyltransferase activity	UGT1A8 UGT1A7 UGT1A9	3.30e-04	35	77	3	GO:0015020
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-7 ERVK-10 ERVK-24	3.90e-04	37	77	3	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-7 ERVK-10 ERVK-24	4.22e-04	38	77	3	GO:0070001
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-7 ERVK-10	7.89e-04	11	77	2	GO:0004523
GeneOntologyMolecularFunction	retinoid binding	UGT1A8 UGT1A7 UGT1A9	8.42e-04	48	77	3	GO:0005501
GeneOntologyMolecularFunction	isoprenoid binding	UGT1A8 UGT1A7 UGT1A9	8.94e-04	49	77	3	GO:0019840
GeneOntologyBiologicalProcess	estrogen catabolic process	UGT1A8 UGT1A7 UGT1A9	4.78e-07	5	76	3	GO:0006711
GeneOntologyBiologicalProcess	flavonoid glucuronidation	UGT1A8 UGT1A7 UGT1A9	4.78e-07	5	76	3	GO:0052696
GeneOntologyBiologicalProcess	phenylpropanoid catabolic process	UGT1A8 UGT1A7 UGT1A9	9.54e-07	6	76	3	GO:0046271
GeneOntologyBiologicalProcess	coumarin catabolic process	UGT1A8 UGT1A7 UGT1A9	9.54e-07	6	76	3	GO:0046226
GeneOntologyBiologicalProcess	flavone metabolic process	UGT1A8 UGT1A7 UGT1A9	9.54e-07	6	76	3	GO:0051552
GeneOntologyBiologicalProcess	phenylpropanoid metabolic process	UGT1A8 UGT1A7 UGT1A9	5.66e-06	10	76	3	GO:0009698
GeneOntologyBiologicalProcess	coumarin metabolic process	UGT1A8 UGT1A7 UGT1A9	5.66e-06	10	76	3	GO:0009804
GeneOntologyBiologicalProcess	xenobiotic glucuronidation	UGT1A8 UGT1A7 UGT1A9	1.03e-05	12	76	3	GO:0052697
GeneOntologyBiologicalProcess	flavonoid metabolic process	UGT1A8 UGT1A7 UGT1A9	1.34e-05	13	76	3	GO:0009812
GeneOntologyBiologicalProcess	cellular glucuronidation	UGT1A8 UGT1A7 UGT1A9	6.10e-05	21	76	3	GO:0052695
GeneOntologyBiologicalProcess	hormone catabolic process	UGT1A8 UGT1A7 UGT1A9	6.10e-05	21	76	3	GO:0042447
GeneOntologyBiologicalProcess	glucuronate metabolic process	UGT1A8 UGT1A7 UGT1A9	1.18e-04	26	76	3	GO:0019585
GeneOntologyBiologicalProcess	uronic acid metabolic process	UGT1A8 UGT1A7 UGT1A9	1.18e-04	26	76	3	GO:0006063
GeneOntologyBiologicalProcess	steroid catabolic process	UGT1A8 UGT1A7 UGT1A9	2.65e-04	34	76	3	GO:0006706
GeneOntologyBiologicalProcess	retinoic acid metabolic process	UGT1A8 UGT1A7 UGT1A9	4.31e-04	40	76	3	GO:0042573
Domain	UDPGT	UGT1A8 UGT1A7 UGT1A9	7.24e-05	21	73	3	PF00201
Domain	UDPGT	UGT1A8 UGT1A7 UGT1A9	7.24e-05	21	73	3	PS00375
Domain	UDP_glucos_trans	UGT1A8 UGT1A7 UGT1A9	7.24e-05	21	73	3	IPR002213
Domain	zf-MYND	CBFA2T3 SMYD3	3.02e-03	21	73	2	PF01753
Domain	Znf_MYND	CBFA2T3 SMYD3	3.31e-03	22	73	2	IPR002893
Domain	ZF_MYND_1	CBFA2T3 SMYD3	3.31e-03	22	73	2	PS01360
Domain	ZF_MYND_2	CBFA2T3 SMYD3	3.31e-03	22	73	2	PS50865
Pathway	KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM	UGT1A8 UGT1A7 UGT1A9 CP	1.51e-05	41	52	4	M7399
Pathway	WP_ESTROGEN_METABOLISM	UGT1A8 UGT1A7 UGT1A9	6.94e-05	22	52	3	MM15888
Pathway	REACTOME_GLUCURONIDATION	UGT1A8 UGT1A7 UGT1A9	9.07e-05	24	52	3	MM14599
Pathway	REACTOME_GLUCURONIDATION	UGT1A8 UGT1A7 UGT1A9	1.03e-04	25	52	3	M17787
Pathway	WP_GLUCURONIDATION	UGT1A8 UGT1A7 UGT1A9	1.03e-04	25	52	3	MM15820
Pathway	KEGG_ASCORBATE_AND_ALDARATE_METABOLISM	UGT1A8 UGT1A7 UGT1A9	1.03e-04	25	52	3	M605
Pathway	WP_GLUCURONIDATION	UGT1A8 UGT1A7 UGT1A9	1.16e-04	26	52	3	M39404
Pathway	KEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS	UGT1A8 UGT1A7 UGT1A9	1.45e-04	28	52	3	M19580
Pathway	REACTOME_PARACETAMOL_ADME	UGT1A8 UGT1A7 UGT1A9	3.94e-04	39	52	3	MM15695
Pathway	REACTOME_ASPIRIN_ADME	UGT1A8 UGT1A7 UGT1A9	5.64e-04	44	52	3	M45014
Pathway	REACTOME_ASPIRIN_ADME	UGT1A8 UGT1A7 UGT1A9	6.02e-04	45	52	3	MM15694
Pathway	KEGG_DRUG_METABOLISM_OTHER_ENZYMES	UGT1A8 UGT1A7 UGT1A9	8.70e-04	51	52	3	M17726
Pathway	KEGG_STARCH_AND_SUCROSE_METABOLISM	UGT1A8 UGT1A7 UGT1A9	9.21e-04	52	52	3	M14171
Pathway	KEGG_STEROID_HORMONE_BIOSYNTHESIS	UGT1A8 UGT1A7 UGT1A9	1.08e-03	55	52	3	M14933
Pathway	WP_CODEINE_AND_MORPHINE_METABOLISM	UGT1A8 UGT1A9	1.18e-03	14	52	2	M39328
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-7 ERVK-10 ERVK-24	4.33e-08	4	78	3	10469592
Pubmed	Risk of diarrhoea in a long-term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the UGT1A8 2 variant allele.	UGT1A8 UGT1A7 UGT1A9	1.08e-07	5	78	3	20565459
Pubmed	Circadian Clock Component Rev-erbα Regulates Diurnal Rhythm of UDP-Glucuronosyltransferase 1a9 and Drug Glucuronidation in Mice.	UGT1A8 UGT1A7 UGT1A9	2.16e-07	6	78	3	32527940
Pubmed	Use of glucuronidation fingerprinting to describe and predict mono- and dihydroxyflavone metabolism by recombinant UGT isoforms and human intestinal and liver microsomes.	UGT1A8 UGT1A7 UGT1A9	2.16e-07	6	78	3	20297805
Pubmed	Assignment of the human UDP glucuronosyltransferase gene (UGT1A1) to chromosome region 2q37.	UGT1A8 UGT1A7 UGT1A9	3.77e-07	7	78	3	8467709
Pubmed	Molecular cloning of two cDNAs encoding the mouse bilirubin/phenol family of UDP-glucuronosyltransferases (mUGTBr/p).	UGT1A8 UGT1A7 UGT1A9	3.77e-07	7	78	3	8464825
Pubmed	Cyp3a11-mediated testosterone-6β-hydroxylation decreased, while UGT1a9-mediated propofol O-glucuronidation increased, in mice with diabetes mellitus.	UGT1A8 UGT1A7 UGT1A9	3.77e-07	7	78	3	27514509
Pubmed	Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation.	UGT1A8 UGT1A7 UGT1A9	6.03e-07	8	78	3	17179145
Pubmed	Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.	UGT1A8 UGT1A7 UGT1A9	6.03e-07	8	78	3	20610558
Pubmed	Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms.	UGT1A8 UGT1A7 UGT1A9	6.03e-07	8	78	3	18052087
Pubmed	A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.	UGT1A8 UGT1A7 UGT1A9	9.03e-07	9	78	3	22511988
Pubmed	Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.	UGT1A8 UGT1A7 UGT1A9	1.29e-06	10	78	3	23642732
Pubmed	UDP-glucuronosyltransferases.	UGT1A8 UGT1A7 UGT1A9	1.29e-06	10	78	3	11465080
Pubmed	A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.	UGT1A8 UGT1A7 UGT1A9	1.29e-06	10	78	3	23371916
Pubmed	A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.	UGT1A8 UGT1A7 UGT1A9	1.29e-06	10	78	3	22558097
Pubmed	Influence of drug transporters and UGT polymorphisms on pharmacokinetics of phenolic glucuronide metabolite of mycophenolic acid in Japanese renal transplant recipients.	UGT1A8 UGT1A7 UGT1A9	1.77e-06	11	78	3	18695635
Pubmed	Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.	UGT1A8 UGT1A7 UGT1A9	2.35e-06	12	78	3	20308471
Pubmed	Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.	UGT1A8 UGT1A7 UGT1A9	2.35e-06	12	78	3	19419973
Pubmed	Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.	UGT1A8 UGT1A7 UGT1A9	2.35e-06	12	78	3	11434514
Pubmed	UGT1A1 is a major locus influencing bilirubin levels in African Americans.	UGT1A8 UGT1A7 UGT1A9	3.05e-06	13	78	3	22085899
Pubmed	Genome-wide analysis of hepatic lipid content in extreme obesity.	UGT1A8 UGT1A7 UGT1A9	3.05e-06	13	78	3	25246029
Pubmed	Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.	UGT1A8 UGT1A7 UGT1A9	3.88e-06	14	78	3	21646302
Pubmed	Human UDP-glucuronosyltransferases: metabolism, expression, and disease.	UGT1A8 UGT1A7 UGT1A9	3.88e-06	14	78	3	10836148
Pubmed	Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.	UGT1A8 UGT1A7 UGT1A9	3.88e-06	14	78	3	14672974
Pubmed	The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.	UGT1A8 UGT1A7 UGT1A9	3.88e-06	14	78	3	9295054
Pubmed	Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene.	UGT1A7 UGT1A9	4.97e-06	2	78	2	11677206
Pubmed	Pharmacogenetic effect of the UGT polymorphisms on mycophenolate is modified by calcineurin inhibitors.	UGT1A8 UGT1A9	4.97e-06	2	78	2	18568343
Pubmed	UGT1A7 and UGT1A9 polymorphisms predict response and toxicity in colorectal cancer patients treated with capecitabine/irinotecan.	UGT1A7 UGT1A9	4.97e-06	2	78	2	15709193
Pubmed	Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs.	UGT1A7 UGT1A9	4.97e-06	2	78	2	12944498
Pubmed	Influence of UGT1A7 and UGT1A9 intronic I399 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients.	UGT1A7 UGT1A9	4.97e-06	2	78	2	17529886
Pubmed	Genome-wide association meta-analysis for total serum bilirubin levels.	UGT1A8 UGT1A7 UGT1A9	5.95e-06	16	78	3	19414484
Pubmed	Genome-wide association of serum bilirubin levels in Korean population.	UGT1A8 UGT1A7 UGT1A9	7.21e-06	17	78	3	20639394
Pubmed	Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.	UGT1A8 UGT1A7 UGT1A9	8.64e-06	18	78	3	20056724
Pubmed	A genome-wide assessment of variability in human serum metabolism.	UGT1A8 UGT1A7 UGT1A9	1.02e-05	19	78	3	23281178
Pubmed	Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan.	UGT1A7 UGT1A9	1.49e-05	3	78	2	19364970
Pubmed	Cyclin-Dependent Kinase 5 Dysfunction Contributes to Depressive-like Behaviors in Huntington's Disease by Altering the DARPP-32 Phosphorylation Status in the Nucleus Accumbens.	PPP1R1B HTT	1.49e-05	3	78	2	31060804
Pubmed	Cooperative Regulation of Intestinal UDP-Glucuronosyltransferases 1A8, -1A9, and 1A10 by CDX2 and HNF4α Is Mediated by a Novel Composite Regulatory Element.	UGT1A8 UGT1A9	1.49e-05	3	78	2	29519853
Pubmed	Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin.	UGT1A7 UGT1A9	1.49e-05	3	78	2	16636344
Pubmed	Genetic polymorphisms of UGT1A8, UGT1A9 and HNF-1α and gastrointestinal symptoms in renal transplant recipients taking mycophenolic acid.	UGT1A8 UGT1A9	1.49e-05	3	78	2	23721685
Pubmed	MiR-3138 deteriorates the insulin resistance of HUVECs via KSR2/AMPK/GLUT4 signaling pathway.	KSR2 SLC2A4	1.49e-05	3	78	2	33509040
Pubmed	Raloxifene glucuronidation in liver and intestinal microsomes of humans and monkeys: contribution of UGT1A1, UGT1A8 and UGT1A9.	UGT1A8 UGT1A9	1.49e-05	3	78	2	26247833
Pubmed	The impact of UGT1A8, UGT1A9, and UGT2B7 genetic polymorphisms on the pharmacokinetic profile of mycophenolic acid after a single oral dose in healthy volunteers.	UGT1A8 UGT1A9	1.49e-05	3	78	2	17339869
Pubmed	Differences in UGT1A1, UGT1A7, and UGT1A9 polymorphisms between Uzbek and Japanese populations.	UGT1A7 UGT1A9	1.49e-05	3	78	2	24453052
Pubmed	UGT genotype may contribute to adverse events following medication with mycophenolate mofetil in pediatric kidney transplant recipients.	UGT1A8 UGT1A9	1.49e-05	3	78	2	19225446
Pubmed	[Influence of genetic polymorphisms in UGT1A1, UGT1A7 and UGT1A9 on the pharmacokynetics of irinotecan, SN-38 and SN-38G].	UGT1A7 UGT1A9	1.49e-05	3	78	2	23789755
Pubmed	Nemo-like kinase reduces mutant huntingtin levels and mitigates Huntington's disease.	PPP1R1B HTT	1.49e-05	3	78	2	32242231
Pubmed	Genetic linkage of UGT1A7 and UGT1A9 polymorphisms to UGT1A1*6 is associated with reduced activity for SN-38 in Japanese patients with cancer.	UGT1A7 UGT1A9	1.49e-05	3	78	2	17406868
Pubmed	Modulation of the human glucuronosyltransferase UGT1A pathway by splice isoform polypeptides is mediated through protein-protein interactions.	UGT1A8 UGT1A7	1.49e-05	3	78	2	19996319
Pubmed	Characterization of common UGT1A8, UGT1A9, and UGT2B7 variants with different capacities to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone.	UGT1A8 UGT1A9	1.49e-05	3	78	2	16397224
Pubmed	Cloning and characterization of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 gene promoters: differential regulation through an interior-like region.	UGT1A8 UGT1A9	1.49e-05	3	78	2	12847094
Pubmed	Genetic determinants influencing human serum metabolome among African Americans.	UGT1A8 UGT1A7 UGT1A9	2.12e-05	24	78	3	24625756
Pubmed	Influence of uridine diphosphate (UDP)-glucuronosyltransferases and ABCC2 genetic polymorphisms on the pharmacokinetics of mycophenolic acid and its metabolites in Chinese renal transplant recipients.	UGT1A8 UGT1A9	2.97e-05	4	78	2	18946804
Pubmed	Population pharmacokinetics and pharmacogenetics of mycophenolic acid following administration of mycophenolate mofetil in de novo pediatric renal-transplant patients.	UGT1A8 UGT1A9	2.97e-05	4	78	2	20147615
Pubmed	UGT1A and TYMS genetic variants predict toxicity and response of colorectal cancer patients treated with first-line irinotecan and fluorouracil combination therapy.	UGT1A7 UGT1A9	2.97e-05	4	78	2	20628391
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-5 ERVK-10	2.97e-05	4	78	2	7983737
Pubmed	Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A16 and 28.	UGT1A7 UGT1A9	2.97e-05	4	78	2	17558305
Pubmed	Genetic polymorphisms of UGT1A8, UGT1A9, UGT2B7 and ABCC2 in Chinese renal transplant recipients and a comparison with other ethnic populations.	UGT1A8 UGT1A9	2.97e-05	4	78	2	23700788
Pubmed	Grey-lethal mutation induces severe malignant autosomal recessive osteopetrosis in mouse and human.	NR2E1 SEC63	4.94e-05	5	78	2	12627228
Pubmed	Pharmacokinetics of mycophenolate mofetil and its glucuronide metabolites in healthy volunteers.	UGT1A7 UGT1A9	4.94e-05	5	78	2	18597651
Pubmed	Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.	ERVK-5 ERVK-7	4.94e-05	5	78	2	11401426
Pubmed	Lack of association between UGT1A7, UGT1A9, ARP, SPINK1 and CFTR gene polymorphisms and pancreatic cancer in Italian patients.	UGT1A7 UGT1A9	4.94e-05	5	78	2	17072959
Pubmed	Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.	UGT1A8 UGT1A9	4.94e-05	5	78	2	15057901
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-5 ERVK-7 ERVK-10 ERVK-24	6.12e-05	94	78	4	21542922
Pubmed	Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population.	UGT1A7 UGT1A9	7.40e-05	6	78	2	19204906
Pubmed	Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.	KSR2 CP SPIDR ADAM12 LRRC47	7.60e-05	193	78	5	22589738
Pubmed	Involvement of human UGT2B7 and 2B15 in rofecoxib metabolism.	UGT1A8 UGT1A9	1.38e-04	8	78	2	12695355
Pubmed	Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk.	UGT1A8 UGT1A7	1.38e-04	8	78	2	15319294
Pubmed	Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.	UGT1A8 UGT1A9	1.77e-04	9	78	2	20732626
Pubmed	A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.	UGT1A8 UGT1A9	1.77e-04	9	78	2	1339448
Pubmed	Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis.	CD55 CFP	2.70e-04	11	78	2	23204401
Pubmed	Human metabolic individuality in biomedical and pharmaceutical research.	UGT1A8 UGT1A7 UGT1A9	2.91e-04	57	78	3	21886157
Pubmed	Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics.	UGT1A7 UGT1A9	3.23e-04	12	78	2	19349540
Pubmed	Genetic variation in the base excision repair pathway and bladder cancer risk.	LIG1 PARP4	3.23e-04	12	78	2	17203305
Pubmed	GPR56 regulates pial basement membrane integrity and cortical lamination.	PPP1R1B ADGRG1	3.81e-04	13	78	2	18509043
Pubmed	Blocking properdin, the alternative pathway, and anaphylatoxin receptors ameliorates renal ischemia-reperfusion injury in decay-accelerating factor and CD59 double-knockout mice.	CD55 CFP	3.81e-04	13	78	2	23427256
Pubmed	Tlx controls proliferation and patterning of lateral telencephalic progenitor domains.	PPP1R1B NR2E1	3.81e-04	13	78	2	14627641
Pubmed	Genetic predisposition to tinnitus in the UK Biobank population.	JAG2 RASSF8	3.81e-04	13	78	2	34518561
Pubmed	Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.	UGT1A8 UGT1A7 UGT1A9	4.49e-04	66	78	3	19898482
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	JAG2 PDE3B PTPRR ABHD2 KSR2 ARHGEF38 ADGRG1 C1orf159 SPIDR SMYD3 HTT	4.76e-04	1489	78	11	28611215
Pubmed	The DNA sequence and biological annotation of human chromosome 1.	RNF186 NOC2L DENND2C C1orf159 FAM43B TSACC SMYD3 OR6K6 LRRC47	4.99e-04	1031	78	9	16710414
Pubmed	Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.	PDE3B HTT	5.84e-04	16	78	2	27721240
Pubmed	Role of the ANKMY2-FKBP38 axis in regulation of the Sonic hedgehog (Shh) signaling pathway.	CBFA2T3 SMYD3	5.84e-04	16	78	2	25077969
Pubmed	Physical and transcriptional map of the mouse Chromosome 10 proximal region syntenic to human 6q16-q21.	NR2E1 SEC63	5.84e-04	16	78	2	11707774
Pubmed	Tlx and Pax6 co-operate genetically to establish the pallio-subpallial boundary in the embryonic mouse telencephalon.	PPP1R1B NR2E1	6.61e-04	17	78	2	12571103
Pubmed	A cluster of cholinergic premotor interneurons modulates mouse locomotor activity.	KCNB1 EVX1	6.61e-04	17	78	2	20005822
Pubmed	Impairment of developmental stem cell-mediated striatal neurogenesis and pluripotency genes in a knock-in model of Huntington's disease.	PPP1R1B HTT	7.42e-04	18	78	2	19955426
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-10 ERVK-24	7.42e-04	18	78	2	18664271
Pubmed	Genome-wide association study link novel loci to endometriosis.	KSR2 ID4	8.28e-04	19	78	2	23472165
Pubmed	An atlas of genetic influences on human blood metabolites.	SLC17A3 UGT1A8 UGT1A7 UGT1A9	8.98e-04	190	78	4	24816252
Pubmed	ETO2 coordinates cellular proliferation and differentiation during erythropoiesis.	BRD1 CBFA2T3	9.19e-04	20	78	2	16407974
Pubmed	Genomic variants in an inbred mouse model predict mania-like behaviors.	KSR2 CP	1.22e-03	23	78	2	29768498
Pubmed	Klf14 is an imprinted transcription factor that regulates placental growth.	FBLN5 CP	1.22e-03	23	78	2	31675530
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	JAG2 FBLN5 ERO1B CLIC1 CD55 ADGRG1 SEC63 ADAM12 HTT	1.46e-03	1201	78	9	35696571
Pubmed	Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.	SLC17A3 CLIC1 CP	1.54e-03	101	78	3	20587610
Pubmed	Molecular genetics of successful smoking cessation: convergent genome-wide association study results.	ARHGEF38 UNC13C ADAM12	1.54e-03	101	78	3	18519826
Pubmed	Proteomics characterization of extracellular space components in the human aorta.	FBLN5 CP CFP	1.54e-03	101	78	3	20551380
Pubmed	Genome-wide analysis of N1ICD/RBPJ targets in vivo reveals direct transcriptional regulation of Wnt, SHH, and hippo pathway effectors by Notch1.	NR2E1 ID4	1.81e-03	28	78	2	22232070
Pubmed	Inactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo.	EVX1 HTT	1.81e-03	28	78	2	16109169
Cytoband	2q37	UGT1A8 UGT1A7 UGT1A9	2.05e-05	31	78	3	2q37
Cytoband	11q23.1	ARHGAP20 FDXACB1	1.83e-03	37	78	2	11q23.1
Cytoband	17q25	TRIM47 CARD14	2.03e-03	39	78	2	17q25
GeneFamily	UDP glucuronosyltransferases	UGT1A8 UGT1A7 UGT1A9	1.11e-04	32	53	3	363
GeneFamily	Zinc fingers MYND-type	CBFA2T3 SMYD3	1.71e-03	21	53	2	87
Coexpression	OSADA_ASCL1_TARGETS_UP	JAG2 ADGRG1 CBFA2T3 SMYD3	8.73e-06	46	74	4	M8556
ToppCell	15-Trachea-Epithelial-Secretory_progenitor\|Trachea / Age, Tissue, Lineage and Cell class	PTPRR ARHGEF38 CD55 ID4 CP ARHGAP20	6.97e-07	187	74	6	be9fce9e74b2f170a2067f1b31d802912a578329
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNB1 PTPRR CD55 ID4 ADGRG1 ADAM12	7.19e-07	188	74	6	0aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNB1 PTPRR CD55 ID4 ADGRG1 ADAM12	7.65e-07	190	74	6	a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNB1 PTPRR CD55 ID4 ADGRG1 ADAM12	7.65e-07	190	74	6	25525fee1da8a808034d9c916159fd0b6b26bce8
ToppCell	P03-Endothelial-large_vessel_endothelial_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBLN5 KCNB1 CLIC1 PTPRR CBFA2T3 TRIM47	7.89e-07	191	74	6	b680e0c35f1004be36f9f0680ae3c62952e2b607
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TNK1 RNF186 SLC17A3 RP1 SLC2A4	6.85e-06	159	74	5	c186bf05c61fac348cf41973827cced83fafd58a
ToppCell	facs-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN5 KCNB1 SPIDR ARHGAP20 CARD14	9.47e-06	170	74	5	8e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell	facs-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN5 KCNB1 SPIDR ARHGAP20 CARD14	9.47e-06	170	74	5	67d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122\|Adult / Lineage, Cell type, age group and donor	ARHGEF38 CP UNC13C RP1 AGBL1	1.12e-05	176	74	5	3fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	JAG2 FBLN5 PTPRR APCDD1L CALHM4	1.12e-05	176	74	5	52af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCell	PCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	RNF186 KSR2 ADGRG1 CBFA2T3 SIT1	1.32e-05	182	74	5	dc29e8735c3562ce32322351d28f7d9709208ebf
ToppCell	(5)_Epithelial_cells-(5)_Glands_duct\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	RNF186 KCNB1 PPP1R1B ARHGEF38 CP	1.46e-05	186	74	5	219b1aeca17503244fabbb780bca58f22c7c0f27
ToppCell	(5)_Glands_duct\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	RNF186 KCNB1 PPP1R1B ARHGEF38 CP	1.46e-05	186	74	5	ad8d5010e5095508f4995e0c6c016a44e8ffb8dd
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBLN5 PTPRR UNC13C TRIM47 AGBL1	1.50e-05	187	74	5	7170694a1b86fe8d84d96c880ffe57af09bdc026
ToppCell	COPD-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	FBLN5 SLC17A3 PTPRR CP ARHGAP20	1.66e-05	191	74	5	ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell	P07-Endothelial-large_vessel_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBLN5 KCNB1 PTPRR CBFA2T3 TRIM47	1.66e-05	191	74	5	d162917816dd2e4767c97447c1cddae9397713ab
ToppCell	IPF-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	JAG2 FBLN5 SLC17A3 PTPRR CP	1.70e-05	192	74	5	e911e286da26202853f9650ba3cdefe5a5c9b585
ToppCell	Control-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	FBLN5 SLC17A3 PTPRR ID4 CP	1.70e-05	192	74	5	7e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNB1 PTPRR ID4 ADGRG1 CBFA2T3	1.75e-05	193	74	5	d485634c564b268e344b6a2863c26f6adaec9e38
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNB1 CD55 ID4 ADGRG1 CBFA2T3	1.79e-05	194	74	5	c8b9551b93a5aed62154b487db90130604a6125c
ToppCell	remission-CD4+_Tcm\|World / disease stage, cell group and cell class	PDE3B FBLN5 TRIM47 ADAM12 SIT1	1.84e-05	195	74	5	365a06e2fb48ec5262a4e2580ba5a592e48127e0
ToppCell	(6)_Endothelial_cells-(6)_Endothelial-B_(Artery)\|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	JAG2 FBLN5 PTPRR ID4 CP	1.88e-05	196	74	5	f540cf17b4405a6dd38d2b6123e6541d0aac889e
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	HYAL4 PPP1R1B TSACC ADAM12 CARD14	1.93e-05	197	74	5	1ffbbe44db0fd3ebd91ad16ab0b91153de5d7c6d
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Macroglial-Astrocyte\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	ACSBG1 NR2E1 ID4 ADGRG1 TRIM47	2.07e-05	200	74	5	29f82e2ad2f1888b6b236a4392b88a84351b8ddc
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Macroglial\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	ACSBG1 NR2E1 ID4 ADGRG1 TRIM47	2.07e-05	200	74	5	1598a9e8efa72fda7d12df07e7716b326cdf1d5e
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_D\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	C15orf62 SLC17A3 VSIG8 TSACC	5.62e-05	125	74	4	9e98dcfdc768ae492f453efc08926164bbb0a909
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2C ARHGEF38 CP STPG2	8.25e-05	138	74	4	611fe0fb284e12678f9c47a0bdbfc367a93c52b3
ToppCell	droplet-Kidney-nan-3m-Lymphocytic-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNB1 TRMT44 CD55 FDXACB1	9.22e-05	142	74	4	a88bf4bcc80206b16dcc504cc19a3380d01e34a4
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NR2E1 ID4 CP ADAM12	9.73e-05	144	74	4	7de962346ba9653d90dd13bb7d977fe44d200bba
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chodl\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PARP4 CLIC1 VSIG8 SIT1	9.73e-05	144	74	4	b622b605f7ec6083ec06c8ea0fd171e07c52f3de
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PLEKHF1 NR2E1 ID4 CP	9.99e-05	145	74	4	78f5f4b96420c7f391e4d32a9ed151ed95fad90b
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NR2E1 ID4 CP ADAM12	1.11e-04	149	74	4	10ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCell	Int-URO-Lymphocyte-T_NK-CD8_Naive\|Int-URO / Disease, Lineage and Cell Type	PDE3B FBLN5 DENND2C TRIM47	1.20e-04	152	74	4	52d6f9cf1f4637c922f582705d625b4cbe3dc0c2
ToppCell	COVID-19-Heart-CM_5_(RYR2-)\|Heart / Disease (COVID-19 only), tissue and cell type	IGFN1 DENND2C UNC13C AGBL1	1.29e-04	155	74	4	d7e26696fd9c0a759524f331243db43059b33ed9
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C12orf56 UNC13C TSACC AGBL1	1.36e-04	157	74	4	370f44047ef438b8f1124c2c2761c150c0d8c57f
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_D\|390C / Donor, Lineage, Cell class and subclass (all cells)	SLC17A3 PTPRR PLEKHF1 ADGRG1	1.50e-04	161	74	4	b60b4fd34a3ad4bf1813e6cc24aa7e04f9e53e4c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3B KCNB1 ARHGAP20 SLC2A4	1.50e-04	161	74	4	4f25eeabb841b0b9204cdd4e71d5e131e7868184
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3B KCNB1 ARHGAP20 SLC2A4	1.50e-04	161	74	4	a006491c991e6a134be20ad75092a91f3b7c3c91
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar-Club_cell\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	RNF186 PPP1R1B ARHGEF38 CD55	1.53e-04	162	74	4	aed15eef32419b8a4e2afdb9776c2bf2802e96f1
ToppCell	T_cells-Tph_and_Tfh\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	PDE3B KSR2 ADGRG1 SIT1	1.53e-04	162	74	4	146058f2d60846376078916055d08f68562e3a7c
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARHGEF38 CP RP1 AGBL1	1.53e-04	162	74	4	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	nucseq-Immune-Hematopoietic-Granulocytic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PARP4 CBFA2T3 ADAM12 SMYD3	1.64e-04	165	74	4	37615622c736e43260c38016e7c9e565ac97a3e8
ToppCell	nucseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PARP4 CBFA2T3 ADAM12 SMYD3	1.64e-04	165	74	4	640bb71e74a61df2fcb01ceeabe4c493ef836b21
ToppCell	nucseq-Immune-Hematopoietic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PARP4 CBFA2T3 ADAM12 SMYD3	1.64e-04	165	74	4	f3df74b5763130c71c0a482a3a23f6b22acc2892
ToppCell	Bronchial_Biopsy-Immune-T_and_NK\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	JAG2 FBLN5 RP1 ADAM12	1.76e-04	168	74	4	435b2f238fbb3f50427e8cdecf2220615015153c
ToppCell	Mild_COVID-19-Myeloid-MoAM5\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	DENND2C ID4 CFP CARD14	1.84e-04	170	74	4	b2daf46ab5a49590ede8f75e4240bfe6e9d8b764
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9\|TCGA-Bladder / Sample_Type by Project: Shred V9	UGT1A8 DENND2C ADGRG1 CP	1.88e-04	171	74	4	adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCell	368C-Endothelial_cells-Endothelial-B_(Artery)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	JAG2 SLC17A3 PTPRR APCDD1L	1.97e-04	173	74	4	ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCell	E15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBLN5 PTPRR CBFA2T3 TRIM47	1.97e-04	173	74	4	b0ff9808e38cb64a734ced498cd0546728746cd5
ToppCell	368C-Endothelial_cells-Endothelial-B_(Artery)\|368C / Donor, Lineage, Cell class and subclass (all cells)	JAG2 SLC17A3 PTPRR APCDD1L	1.97e-04	173	74	4	22200fe74e33e2beae0eed289ca8476bbc0b1b2d
ToppCell	metastatic_Brain-Endothelial_cells-Stalk-like_ECs\|Endothelial_cells / Location, Cell class and cell subclass	FBLN5 PTPRR ID4 ARHGAP20	2.06e-04	175	74	4	f6a6db992e803d36c866a91706b02f67e0fd3e09
ToppCell	P15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	C15orf62 FBLN5 CP ADAM12	2.06e-04	175	74	4	84d252f3e432231687613299bbea14978bb4b06b
ToppCell	P15-Endothelial-lymphatic_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	C15orf62 FBLN5 CP ADAM12	2.06e-04	175	74	4	a00c6fa9b33640710dd05a3799031147196f0986
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE3B PLEKHF1 RGPD1 ADGRG1	2.10e-04	176	74	4	6b06da40eb97ea2db09f3a769494738b3e5fe3fa
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN5 PTPRR CBFA2T3 TRIM47	2.10e-04	176	74	4	27e6b3ae41068d6cfdda3d46da7df2a27567140e
ToppCell	LPS-IL1RA-Myeloid-Dendritic_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFP VSIG8 CBFA2T3 SIT1	2.10e-04	176	74	4	f3bbe8c1a8d132705eac360cf531261271d84588
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN5 PTPRR CBFA2T3 TRIM47	2.10e-04	176	74	4	d6a5470af9592f34a741265f2ea9651c05c3add3
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN5 KCNB1 PTPRR TRIM47	2.15e-04	177	74	4	6f6cf93893daac6ae228df36219ee3acf8de8f97
ToppCell	facs-Kidney-nan-18m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF10 CD55 ID4 CP	2.15e-04	177	74	4	d4cd54c07f1e51b5485270348fb7195d53465027
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C15orf62 FBLN5 PTPRR TRIM47	2.15e-04	177	74	4	d68132e145bd413404fdbe215b5dbe520e756e50
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERO1B ABHD2 KRTAP26-1 AGBL1	2.20e-04	178	74	4	09a215a0d6e98e4bb920cabda12af08ff4de3c98
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FBLN5 PTPRR APCDD1L CALHM4	2.24e-04	179	74	4	8c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCell	droplet-Lung-nan-18m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSBG1 UNC13C ADAM12 SIT1	2.24e-04	179	74	4	8ebd0c7ac99ac8194fa1a2aac88a893739a97725
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSBG1 UNC13C ADAM12 SIT1	2.29e-04	180	74	4	81c7086399256260e59424b7410feec514ce8027
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF38 RP1 RASSF8 STPG2	2.29e-04	180	74	4	9e09b3dfe344b5d50520711513d389865d73a861
ToppCell	facs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBLN5 KCNB1 PTPRR ARHGAP20	2.34e-04	181	74	4	72c28baf4fd417ff4a7068603830d55074960144
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LIG1 PPP1R1B CD55 CP	2.34e-04	181	74	4	e0c46e2d52c97893e5894a51d2699e8a8a11eefc
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ACSBG1 UNC13C ADAM12 SIT1	2.34e-04	181	74	4	c7ad10a696d94b9ee91cd7e62761d356d5106eda
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PTPRR ARHGEF38 CD55 CP	2.34e-04	181	74	4	bab282cb0d9fc049f6fb094cf8b1fba104f4ea17
ToppCell	facs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBLN5 KCNB1 PTPRR ARHGAP20	2.34e-04	181	74	4	2ac4d3e8987d5a009d7908d8787e18165826202a
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ACSBG1 UNC13C ADAM12 SIT1	2.34e-04	181	74	4	eaa3a2c268cce527004ae656d35e037b984fb4c7
ToppCell	facs-Lung-3m-Endothelial-venous_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBLN5 KCNB1 PTPRR ARHGAP20	2.34e-04	181	74	4	2628c7ac345eaaeecf8e34617e81948925962cb9
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	ARHGEF38 CD55 CP RP1	2.34e-04	181	74	4	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 CLIC1 CP RP1	2.39e-04	182	74	4	e6a734fb29105093d4cbfc3d0619a825b66da034
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CLIC1 ABHD2 WDR83OS ADGRG1	2.39e-04	182	74	4	c6172aca2475bf0948a78e39f0dae6388504a915
ToppCell	E15.5-Endothelial-large_vessel_endothelial_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBLN5 PTPRR CBFA2T3 TRIM47	2.39e-04	182	74	4	345d0f9d5ee30434bc2aac17608ccdc9e61c8fa3
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 CLIC1 CP RP1	2.39e-04	182	74	4	ccc313ecc0bfd8e2c6bb83a565b427b2310485ec
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 CLIC1 CP RP1	2.39e-04	182	74	4	b9f758961fb4a586ae86fa0b25edb8ce4616d644
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C12orf56 PPP1R1B ADGRG1 SLC2A4	2.44e-04	183	74	4	6b5fa169477821355d1ab7aa11935cdfde1c339c
ToppCell	PND07-28-samps-Epithelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	RNF186 PPP1R1B ARHGEF38 CD55	2.44e-04	183	74	4	a98f1d71d82ed6cca996f74352ab834fb6e95206
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN5 PTPRR CBFA2T3 TRIM47	2.44e-04	183	74	4	fc9a7ba148c22d0c8a46f6bc56c772929ac496f7
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	PDE3B ABHD2 SLC2A4 HTT	2.49e-04	184	74	4	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	Endothelial-E\|World / shred on cell class and cell subclass (v4)	FBLN5 PTPRR CBFA2T3 TRIM47	2.49e-04	184	74	4	b4c561924c508536fd2112e91e32176b95fdf63a
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARHGEF38 UNC13C RP1 AGBL1	2.49e-04	184	74	4	102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBLN5 ID4 ARHGAP20 ADAM12	2.49e-04	184	74	4	4d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C15orf62 ARHGEF38 CD55 CP	2.49e-04	184	74	4	01c19a830348ab0b9c02c1546a439de70ee10f97
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Adult / Lineage, Cell type, age group and donor	ARHGEF38 CP UNC13C AGBL1	2.54e-04	185	74	4	673f0c688ae6984bc8027df2da335787924f4137
ToppCell	facs-Trachea-nan-24m-Endothelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 PTPRR ADGRG1 CBFA2T3	2.54e-04	185	74	4	dec60254204014083ff3b4aec0cc75410950a486
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	UNC13C RP1 RASSF8 STPG2	2.54e-04	185	74	4	03f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	JAG2 FBLN5 CP VSIG8	2.54e-04	185	74	4	b57dae20c21f984edd2acee4344d86f033108ebf
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	JAG2 FBLN5 CP VSIG8	2.54e-04	185	74	4	d3b054d203e575c1bb5455aa7a2e551a0957a760
ToppCell	facs-Trachea-nan-24m-Endothelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 PTPRR ADGRG1 CBFA2T3	2.54e-04	185	74	4	201465dc0d7aa0336a36d37805cae1155a5adfe1
ToppCell	facs-Trachea-nan-24m-Endothelial-endothelial_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 PTPRR ADGRG1 CBFA2T3	2.54e-04	185	74	4	334f006c3ef33338ff8d649309d3f448733a3a99
ToppCell	P28-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBLN5 KCNB1 PTPRR ARHGAP20	2.60e-04	186	74	4	153c8b2fd8a6e2141ca97c626f82e5f081f3180a
ToppCell	Mesenchymal_cells-Adipo-CAR\|World / Lineage and Cell class	FBLN5 PLEKHF1 ID4 CP	2.60e-04	186	74	4	6ca8ce7ced91d6308b7c056032ffec1b37c974bf
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	KCNB1 C12orf56 ID4 UNC13C	2.65e-04	187	74	4	f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLIC1 PTPRR CBFA2T3 TRIM47	2.65e-04	187	74	4	3e25c15fa29f8c738044914e8b3420d5713f18d9
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	KCNB1 C12orf56 ID4 UNC13C	2.65e-04	187	74	4	02e7246ef5ad41773d14426254e139b156d45c1d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IGFN1 ACSBG1 ID4 ADGRG1	2.65e-04	187	74	4	4d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	ARHGEF38 CP RP1 AGBL1	2.65e-04	187	74	4	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
Drug	naringenin chalcone	UGT1A8 UGT1A7 UGT1A9	3.42e-07	5	75	3	ctd:C027329
Drug	anthrarobin	UGT1A8 UGT1A7 UGT1A9	3.42e-07	5	75	3	ctd:C032186
Drug	1,2,5,8-tetrahydroxy anthraquinone	UGT1A8 UGT1A7 UGT1A9	6.82e-07	6	75	3	ctd:C543211
Drug	alloin	UGT1A8 UGT1A7 UGT1A9	6.82e-07	6	75	3	ctd:C006457
Drug	2',5'-dihydroxychalcone	UGT1A8 UGT1A7 UGT1A9	6.82e-07	6	75	3	ctd:C107497
Drug	plumbagin	UGT1A8 UGT1A7 UGT1A9 SLC2A4	7.59e-07	22	75	4	ctd:C014758
Drug	2',4'-dihydroxychalcone	UGT1A8 UGT1A7 UGT1A9	1.19e-06	7	75	3	ctd:C059354
Drug	1,4-dihydroxyanthraquinone	UGT1A8 UGT1A7 UGT1A9	1.90e-06	8	75	3	ctd:C034890
Drug	H-Ni	UGT1A8 UGT1A7 UGT1A9 HTT	2.09e-06	28	75	4	CID000445665
Drug	AC1MRQNQ	UGT1A8 UGT1A7 UGT1A9	2.84e-06	9	75	3	CID003522271
Drug	DHPASiU	UGT1A8 UGT1A7 UGT1A9	2.84e-06	9	75	3	CID000197602
Drug	Chebi:32663	UGT1A8 UGT1A7 UGT1A9	2.84e-06	9	75	3	CID005460873
Drug	3-iodophenol	UGT1A8 UGT1A7 UGT1A9	2.84e-06	9	75	3	CID000012272
Drug	AC1L4J7U	UGT1A8 UGT1A7 UGT1A9	2.84e-06	9	75	3	CID000186631
Drug	2,6-dihydroxyanthraquinone	UGT1A8 UGT1A7 UGT1A9	4.05e-06	10	75	3	ctd:C034889
Drug	4-nitrophenyl)imidazole	UGT1A8 UGT1A7 UGT1A9	5.56e-06	11	75	3	CID000123155
Drug	AC1O5XMV	UGT1A8 UGT1A7 UGT1A9	5.56e-06	11	75	3	CID006442661
Drug	N-OH-DABZ	UGT1A8 UGT1A7 UGT1A9	7.39e-06	12	75	3	CID000051366
Drug	1-O-beta-D-glucopyranosyl-D-mannitol	UGT1A8 UGT1A7 UGT1A9	7.39e-06	12	75	3	CID000088735
Drug	4-hydroxyestrone	UGT1A8 UGT1A7 UGT1A9	7.39e-06	12	75	3	ctd:C026418
Drug	2,4,6-TCB	UGT1A8 UGT1A7 UGT1A9	7.39e-06	12	75	3	CID000037247
Drug	7,7,7-triphenylheptanoic acid	UGT1A8 UGT1A7 UGT1A9	7.39e-06	12	75	3	CID000276709
Drug	nonanoyl-N-methylglucamide	UGT1A8 UGT1A7 UGT1A9	7.39e-06	12	75	3	CID000160090
Drug	2-hydroxyestrone	UGT1A8 UGT1A7 UGT1A9	9.59e-06	13	75	3	ctd:C024980
Drug	tritanol	UGT1A8 UGT1A7 UGT1A9	9.59e-06	13	75	3	CID000006457
Drug	5-azido-UDP-glucuronic acid	UGT1A8 UGT1A7 UGT1A9	9.59e-06	13	75	3	CID003081279
Drug	cotinine-N-glucuronide	UGT1A8 UGT1A7 UGT1A9	9.59e-06	13	75	3	CID000000411
Drug	alizarin	UGT1A8 UGT1A7 UGT1A9	9.59e-06	13	75	3	ctd:C010078
Drug	Z 338	UGT1A8 UGT1A9	1.07e-05	2	75	2	ctd:C410959
Drug	propranolol glucuronide	UGT1A8 UGT1A7 UGT1A9	1.22e-05	14	75	3	CID000119515
Drug	PCB-61	UGT1A8 UGT1A7 UGT1A9	1.22e-05	14	75	3	CID000036401
Drug	2,2',3,5,5'-pentachlorobiphenyl	UGT1A8 UGT1A7 UGT1A9	1.52e-05	15	75	3	CID000040469
Drug	coumarin-3-carboxylic acid	UGT1A8 UGT1A7 UGT1A9	1.52e-05	15	75	3	CID000010752
Drug	bergamottin	UGT1A8 UGT1A7 UGT1A9	1.52e-05	15	75	3	ctd:C068337
Drug	sulforaphane nitrile	UGT1A8 UGT1A7 UGT1A9	1.52e-05	15	75	3	CID000543743
Drug	afloqualone	UGT1A8 UGT1A7 UGT1A9	1.52e-05	15	75	3	CID000002040
Drug	naphthyl sulphate	UGT1A8 UGT1A7 UGT1A9	1.52e-05	15	75	3	CID000114775
Drug	quercetin-3,4'-diglucoside	UGT1A8 UGT1A7 UGT1A9	1.86e-05	16	75	3	CID005320835
Drug	1'-hydroxyestragole	UGT1A8 UGT1A7 UGT1A9	1.86e-05	16	75	3	CID000040003
Drug	bilirubin-phosphate	UGT1A8 UGT1A7 UGT1A9	1.86e-05	16	75	3	CID005497144
Drug	3 beta,5 alpha,25R)- 3-hydroxyspirostan-12-one	UGT1A8 UGT1A7 UGT1A9	2.26e-05	17	75	3	CID000003573
Drug	6-hydroxychrysene	UGT1A8 UGT1A7 UGT1A9	2.26e-05	17	75	3	CID000037766
Drug	ethyl-beta-D-6-glucosiduronic acid	UGT1A8 UGT1A7 UGT1A9	2.70e-05	18	75	3	CID000152226
Drug	Br 2	UGT1A8 UGT1A7 UGT1A9	2.70e-05	18	75	3	CID003060900
Drug	SureCN12722713	UGT1A8 UGT1A7 UGT1A9	2.70e-05	18	75	3	CID005488034
Drug	2,3,7-trichlorodibenzo-p-dioxin	UGT1A8 UGT1A7 UGT1A9	2.70e-05	18	75	3	CID000036614
Drug	ApApG	UGT1A8 UGT1A7 UGT1A9	2.70e-05	18	75	3	CID003081975
Drug	C1 11-32	UGT1A8 UGT1A7 UGT1A9	2.70e-05	18	75	3	CID000443077
Drug	C11131	UGT1A8 UGT1A7 UGT1A9	2.70e-05	18	75	3	CID000443076
Drug	almokalant	UGT1A8 UGT1A7 UGT1A9	3.20e-05	19	75	3	CID003033962
Drug	9-OH-risperidone	UGT1A8 UGT1A7 UGT1A9	3.20e-05	19	75	3	CID000475100
Drug	5alpha-spirostan-3beta-ol	UGT1A8 UGT1A7 UGT1A9	3.20e-05	19	75	3	CID000091433
Drug	tectochrysin	UGT1A8 UGT1A7 UGT1A9	3.76e-05	20	75	3	CID005281954
Drug	AC1L1OBF	UGT1A8 UGT1A7 UGT1A9	3.76e-05	20	75	3	CID000032736
Drug	4'-hydroxydiclofenac	UGT1A8 UGT1A7 UGT1A9	3.76e-05	20	75	3	CID000116545
Drug	entacapone	UGT1A8 UGT1A7 UGT1A9	3.76e-05	20	75	3	ctd:C071192
Drug	morin	UGT1A8 UGT1A7 UGT1A9 CP	4.03e-05	58	75	4	ctd:C008548
Drug	estriol-16-glucuronide	UGT1A8 UGT1A7 UGT1A9	4.38e-05	21	75	3	CID000122281
Drug	dulcin	UGT1A8 UGT1A7 UGT1A9	4.38e-05	21	75	3	CID000009013
Drug	7-hydroxycoumarin	UGT1A8 UGT1A7 UGT1A9	4.38e-05	21	75	3	ctd:C031477
Drug	Benzamidoxime hydrochloride	UGT1A8 UGT1A7 UGT1A9	4.38e-05	21	75	3	CID000069186
Drug	fisetin	UGT1A8 UGT1A7 UGT1A9 SLC2A4	4.60e-05	60	75	4	ctd:C017875
Drug	Isocarboxazid [59-63-2]; Up 200; 17.2uM; PC3; HT_HG-U133A	TNK1 ERO1B ACSBG1 ARHGEF38 ID4 ADGRG1	4.90e-05	198	75	6	7383_UP
Drug	amonafide	UGT1A8 UGT1A7 UGT1A9	5.05e-05	22	75	3	CID000050515
Drug	N-methylpiperazine	UGT1A8 UGT1A7 UGT1A9	5.05e-05	22	75	3	CID000053167
Drug	amidoxime	UGT1A8 UGT1A7 UGT1A9	5.80e-05	23	75	3	CID000465967
Drug	estradiol-3-glucuronide	UGT1A8 UGT1A7 UGT1A9	5.80e-05	23	75	3	CID000066651
Drug	phenanthridine	UGT1A8 UGT1A7 UGT1A9	5.80e-05	23	75	3	CID000009189
Drug	sitafloxacin	UGT1A7 UGT1A9	6.40e-05	4	75	2	ctd:C076246
Drug	2-vanillin	UGT1A8 UGT1A7	6.40e-05	4	75	2	ctd:C060843
Drug	naloxonazine	PPP1R1B SLC2A4	6.40e-05	4	75	2	ctd:C034643
Drug	hydratropic acid	UGT1A8 UGT1A7	6.40e-05	4	75	2	ctd:C013025
Drug	diphenylacetic acid	UGT1A8 UGT1A7	6.40e-05	4	75	2	ctd:C037760
Drug	cinnamic acid	UGT1A8 UGT1A7 SLC2A4	6.61e-05	24	75	3	ctd:C029010
Drug	AS-3201	UGT1A8 UGT1A7 UGT1A9	6.61e-05	24	75	3	CID000153948
Drug	5-MOP	UGT1A8 UGT1A7 UGT1A9	7.49e-05	25	75	3	CID000002355
Drug	Hymecromone	UGT1A8 UGT1A7 UGT1A9	7.49e-05	25	75	3	ctd:D006923
Drug	AzMC	UGT1A8 UGT1A7 UGT1A9	7.49e-05	25	75	3	CID000064986
Drug	N-acetylbenzidine	UGT1A8 UGT1A7 UGT1A9	7.49e-05	25	75	3	CID000018787
Drug	5,6-benzoquinoline	UGT1A8 UGT1A7 UGT1A9	7.49e-05	25	75	3	CID000006796
Drug	N-phenylmaleimide	UGT1A8 UGT1A7 UGT1A9	7.49e-05	25	75	3	CID000013662
Drug	Thymol	UGT1A8 UGT1A7 UGT1A9	8.45e-05	26	75	3	ctd:D013943
Drug	Scopoletin	UGT1A8 UGT1A7 UGT1A9	9.49e-05	27	75	3	ctd:D012603
Drug	DiMeIQx	UGT1A8 UGT1A7 UGT1A9	9.49e-05	27	75	3	CID000104739
Drug	licochalcone A	UGT1A8 UGT1A7 UGT1A9	9.49e-05	27	75	3	ctd:C070840
Drug	diflunisal	UGT1A8 UGT1A7 UGT1A9	9.49e-05	27	75	3	CID000003059
Drug	isoliquiritigenin	UGT1A8 UGT1A7 UGT1A9 SLC2A4	9.95e-05	73	75	4	ctd:C040920
Drug	N-hydroxy-4-aminobiphenyl	UGT1A8 UGT1A7 UGT1A9	1.06e-04	28	75	3	CID000081261
Drug	CARMINE	UGT1A8 UGT1A7 UGT1A9	1.06e-04	28	75	3	CID000014749
Drug	erucin	UGT1A8 UGT1A7 UGT1A9	1.06e-04	28	75	3	CID000078160
Drug	ethyl 2-(4-chlorophenyl)-5-(2-furyl)-4-oxzoleacetate	UGT1A7 UGT1A9	1.06e-04	5	75	2	ctd:C052488
Drug	isovaleric acid	UGT1A8 UGT1A7	1.06e-04	5	75	2	ctd:C008216
Drug	biphenylylacetic acid	UGT1A8 UGT1A7	1.06e-04	5	75	2	ctd:C012776
Drug	emodin	ACSBG1 UGT1A8 UGT1A7 UGT1A9 ID4	1.07e-04	142	75	5	CID000003220
Drug	AC1L1JAL	UGT1A8 UGT1A7 UGT1A9	1.18e-04	29	75	3	CID000004954
Drug	7-hydroxy-4-trifluoromethylcoumarin	UGT1A8 UGT1A7 UGT1A9	1.18e-04	29	75	3	CID005375667
Drug	trans-3'-hydroxycotinine	UGT1A8 UGT1A7 UGT1A9	1.18e-04	29	75	3	CID000000414
Drug	7-hydroxycoumarin glucuronide	UGT1A8 UGT1A7 UGT1A9	1.18e-04	29	75	3	CID000125641
Drug	iberin	UGT1A8 UGT1A7 UGT1A9	1.18e-04	29	75	3	CID000010455
Drug	2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine	UGT1A8 UGT1A7 UGT1A9	1.18e-04	29	75	3	ctd:C060533
Disease	N-acetyl-4-chlorophenylalanine measurement	UGT1A8 UGT1A7 UGT1A9	1.17e-07	5	68	3	EFO_0801060
Disease	5-hydroxyindole sulfate measurement	UGT1A8 UGT1A7 UGT1A9	1.17e-07	5	68	3	EFO_0800085
Disease	nuclear receptor subfamily 1 group D member 2 measurement	UGT1A8 UGT1A7 UGT1A9	1.17e-07	5	68	3	EFO_0801853
Disease	X-21339 measurement	UGT1A8 UGT1A7 UGT1A9	4.07e-07	7	68	3	EFO_0800808
Disease	xanthurenate measurement	SLC17A3 UGT1A8 UGT1A7 UGT1A9	5.86e-07	29	68	4	EFO_0010551
Disease	X-11793--oxidized bilirubin measurement	UGT1A8 UGT1A7 UGT1A9	6.50e-07	8	68	3	EFO_0021260
Disease	Succinimide measurement	UGT1A8 UGT1A7 UGT1A9	6.50e-07	8	68	3	EFO_0022118
Disease	X-11530 measurement	UGT1A8 UGT1A7 UGT1A9	6.50e-07	8	68	3	EFO_0021249
Disease	sulfate of piperine metabolite C16H19NO3 (2) measurement	UGT1A8 UGT1A7 UGT1A9	6.50e-07	8	68	3	EFO_0801034
Disease	cholelithiasis, bilirubin measurement	UGT1A8 UGT1A7 UGT1A9	6.50e-07	8	68	3	EFO_0004570, EFO_0004799
Disease	X-11522 measurement	UGT1A8 UGT1A7 UGT1A9	6.50e-07	8	68	3	EFO_0800696
Disease	X-10458 measurement	UGT1A8 UGT1A7 UGT1A9	6.50e-07	8	68	3	EFO_0800692
Disease	X-24849 measurement	UGT1A8 UGT1A7 UGT1A9	6.50e-07	8	68	3	EFO_0800909
Disease	serum N-desmethylclozapine measurement	UGT1A8 UGT1A7 UGT1A9	6.50e-07	8	68	3	EFO_0600043
Disease	plasma clozapine measurement	UGT1A8 UGT1A7 UGT1A9	6.50e-07	8	68	3	EFO_0600038
Disease	membrane-associated progesterone receptor component 1 measurement	UGT1A8 UGT1A7 UGT1A9	6.50e-07	8	68	3	EFO_0802740
Disease	X-16946 measurement	UGT1A8 UGT1A7 UGT1A9	6.50e-07	8	68	3	EFO_0800766
Disease	X-11442 measurement	UGT1A8 UGT1A7 UGT1A9	9.74e-07	9	68	3	EFO_0021236
Disease	X-11441 measurement	UGT1A8 UGT1A7 UGT1A9	9.74e-07	9	68	3	EFO_0021235
Disease	circulating cell free DNA measurement	UGT1A8 UGT1A7 UGT1A9	9.74e-07	9	68	3	EFO_0004739
Disease	sulfate of piperine metabolite C18H21NO3 (3) measurement	UGT1A8 UGT1A7 UGT1A9	9.74e-07	9	68	3	EFO_0801037
Disease	testis-specific chromodomain protein Y 1 measurement	UGT1A8 UGT1A7 UGT1A9	9.74e-07	9	68	3	EFO_0802127
Disease	sulfate of piperine metabolite C18H21NO3 (1) measurement	UGT1A8 UGT1A7 UGT1A9	9.74e-07	9	68	3	EFO_0801036
Disease	X-11880 measurement	UGT1A8 UGT1A7 UGT1A9	9.74e-07	9	68	3	EFO_0800698
Disease	bilirubin measurement, response to xenobiotic stimulus	UGT1A8 UGT1A7 UGT1A9	9.74e-07	9	68	3	EFO_0004570, GO_0009410
Disease	protein-tyrosine kinase 6 measurement	UGT1A8 UGT1A7 UGT1A9	9.74e-07	9	68	3	EFO_0020691
Disease	X-21448 measurement	UGT1A8 UGT1A7 UGT1A9	1.39e-06	10	68	3	EFO_0800816
Disease	UDP-glucuronosyltransferase 1-6 measurement	UGT1A8 UGT1A7 UGT1A9	1.39e-06	10	68	3	EFO_0802185
Disease	X-23974 measurement	UGT1A8 UGT1A7 UGT1A9	1.39e-06	10	68	3	EFO_0800867
Disease	bilirubin measurement, response to tenofovir	UGT1A8 UGT1A7 UGT1A9	1.39e-06	10	68	3	EFO_0004570, EFO_0009279
Disease	vitamin D deficiency	PDE3B UGT1A8 UGT1A7 UGT1A9	1.61e-06	37	68	4	EFO_0003762
Disease	X-21796 measurement	UGT1A8 UGT1A7 UGT1A9	1.91e-06	11	68	3	EFO_0800825
Disease	pregnenetriol sulfate measurement	UGT1A8 UGT1A7 UGT1A9	1.91e-06	11	68	3	EFO_0800586
Disease	plasma N-desmethylclozapine measurement	UGT1A8 UGT1A7 UGT1A9	1.91e-06	11	68	3	EFO_0600039
Disease	insomnia, bilirubin measurement	UGT1A8 UGT1A7 UGT1A9	1.91e-06	11	68	3	EFO_0004570, EFO_0004698
Disease	histidine betaine (hercynine) measurement	UGT1A8 UGT1A7 UGT1A9	1.91e-06	11	68	3	EFO_0800972
Disease	aldosterone measurement	UGT1A8 UGT1A7 UGT1A9	1.91e-06	11	68	3	EFO_0010219
Disease	biliverdin measurement	UGT1A8 UGT1A7 UGT1A9	2.54e-06	12	68	3	EFO_0021033
Disease	p-cresol glucuronide measurement	UGT1A8 UGT1A7 UGT1A9	2.54e-06	12	68	3	EFO_0800079
Disease	retinol dehydrogenase 16 measurement	UGT1A8 UGT1A7 UGT1A9	3.29e-06	13	68	3	EFO_0802007
Disease	pregnenetriol disulfate measurement	UGT1A8 UGT1A7 UGT1A9	3.29e-06	13	68	3	EFO_0800587
Disease	vitamin D measurement, COVID-19	PDE3B UGT1A8 UGT1A7 UGT1A9	5.05e-06	49	68	4	EFO_0004631, MONDO_0100096
Disease	X-21441 measurement	UGT1A8 UGT1A7 UGT1A9	7.78e-06	17	68	3	EFO_0800814
Disease	low density lipoprotein cholesterol measurement, body fat percentage	UGT1A8 UGT1A7 UGT1A9	7.78e-06	17	68	3	EFO_0004611, EFO_0007800
Disease	angiopoietin-related protein 1 measurement	UGT1A8 UGT1A7 UGT1A9	9.32e-06	18	68	3	EFO_0801382
Disease	tissue factor measurement	UGT1A8 UGT1A7 UGT1A9	1.51e-05	21	68	3	EFO_0010623
Disease	blood 4-oxo-retinoic acid measurement	UGT1A8 UGT1A9	1.57e-05	3	68	2	EFO_0022216
Disease	indole-3-carboxylate measurement	UGT1A8 UGT1A9	1.57e-05	3	68	2	EFO_0800043
Disease	neuroblastoma, cutaneous melanoma	UGT1A8 UGT1A7 UGT1A9	3.68e-05	28	68	3	EFO_0000389, EFO_0000621
Disease	response to dolutegravir	UGT1A8 UGT1A7 UGT1A9	4.55e-05	30	68	3	EFO_0600017
Disease	Asterixis	PPP1R1B CP	7.80e-05	6	68	2	C0232766
Disease	Oral Dyskinesia	PPP1R1B CP	7.80e-05	6	68	2	C0454606
Disease	Ballismus	PPP1R1B CP	7.80e-05	6	68	2	C0752196
Disease	Hemiballismus	PPP1R1B CP	7.80e-05	6	68	2	C0221169
Disease	Lingual-Facial-Buccal Dyskinesia	PPP1R1B CP	7.80e-05	6	68	2	C0152115
Disease	3-carboxy-4-methyl-5-pentyl-2-furanpropionate (3-CMPFP) measurement	UGT1A8 UGT1A9	7.80e-05	6	68	2	EFO_0800566
Disease	Involuntary Movements	PPP1R1B CP	1.09e-04	7	68	2	C0427086
Disease	Dyskinetic syndrome	PPP1R1B CP	1.09e-04	7	68	2	C0013384
Disease	neuroimaging measurement	JAG2 SLC17A3 PPP1R1B KSR2 RGPD1 LRCH4 TRIM47 AGBL1 STPG2 HTT	1.61e-04	1069	68	10	EFO_0004346
Disease	epilepsy (is_implicated_in)	KCNB1 CP	1.86e-04	9	68	2	DOID:1826 (is_implicated_in)
Disease	indoleacetate measurement	UGT1A8 UGT1A9	2.33e-04	10	68	2	EFO_0021015
Disease	urate measurement, spine bone mineral density	UGT1A8 UGT1A7 UGT1A9	3.30e-04	58	68	3	EFO_0004531, EFO_0007701
Disease	X-24588 measurement	UGT1A8 UGT1A9	4.02e-04	13	68	2	EFO_0800898
Disease	apolipoprotein B measurement	PDE3B UGT1A8 UGT1A7 UGT1A9 RP1 SLC2A4 HTT	8.29e-04	663	68	7	EFO_0004615
Disease	thyroxine measurement	UGT1A8 UGT1A7 UGT1A9	9.43e-04	83	68	3	EFO_0005130
Disease	amino acid measurement	LIG1 PTPRR LRCH4 UNC13C ADAM12 SLC2A4 HTT	9.44e-04	678	68	7	EFO_0005134
Disease	hormone measurement	UGT1A8 UGT1A7 UGT1A9	9.76e-04	84	68	3	EFO_0004730
Disease	cholelithiasis	UGT1A8 UGT1A7 UGT1A9	1.12e-03	88	68	3	EFO_0004799
Disease	serum metabolite measurement	PARP4 SLC17A3 UGT1A8 UGT1A7 APCDD1L UGT1A9 ARHGAP20 AGBL1	1.45e-03	945	68	8	EFO_0005653
Disease	energy expenditure	KCNB1 SMYD3	1.77e-03	27	68	2	EFO_0005109
Disease	gallstones	UGT1A8 UGT1A7 UGT1A9	2.01e-03	108	68	3	EFO_0004210
Disease	bipolar disorder (is_implicated_in)	PPP1R1B BRD1	2.04e-03	29	68	2	DOID:3312 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
TVCAPYIPPQRLNRI	BRD1	446	O95696
RCLNLKSPTAPPDLY	ABHD2	31	P08910
KYPLLLCELRNSTPP	ARHGEF38	246	Q9NXL2
NCFKPRSVYRPLNPL	ERO1B	206	Q86YB8
RVLSQPYPRPELLCA	EVX1	311	P49640
PEKRPTSYQAPLVLC	APCDD1L	441	Q8NCL9
DSYPPKDNPRRLLQC	ADAM12	781	O43184
RPNKVLRYKPPPSEC	WDR83OS	11	Q9Y284
LQILRQCYPTSPLPL	AGBL1	261	Q96MI9
LYRQSLPPLAKLRPQ	RASSF8	101	Q8NHQ8
LSLLPPYICQLPLRV	LRCH4	126	O75427
PLIVCRRPYLKVFNP	CP	896	P00450
LIPRKVPSLCSARYG	SLC17A3	26	O00476
QLVLLPFCPESPRYL	SLC2A4	216	P14672
DVLYQCKNFTPPPRR	JAG2	1146	Q9Y219
RAVKGPLLYCARPPQ	LRRC47	381	Q8N1G4
LRRLLNAKCAYRPPP	FAM43B	236	Q6ZT52
PCDINNPLRKPPRYS	KSR2	476	Q6VAB6
PGYRREPSLSPKLTC	CD55	131	P08174
YVKSCVSPLRQDPPR	PDE3B	31	Q13370
RARQRLCTPLLPKYP	CFP	401	P27918
CLQVYPTAPKRQRPS	ERVK-5	16	P61583
CLQVYPTAPKRQRPS	ERVK-7	16	P61582
KPNPPSLAKYRALRC	PARP4	366	Q9UKK3
CYSRLRRLVPTIPPN	ID4	71	P47928
KRPCTLNPAQRYSPS	CBFA2T3	316	O75081
GCIKLIPTARFYPLR	NOC2L	441	Q9Y3T9
YKTILPNPLSRVCLR	PTPRR	421	Q15256
CLQVYPTAPKRQRPS	ERVK-24	16	P61581
KCRPYLVNLLPCLTR	HTT	201	P42858
PLPTSPKFLRQNCIY	KCNB1	801	Q14721
PSRLTPYLRQAKVLC	CARD14	36	Q9BXL6
SISCLKPARLPIYQR	HYAL4	31	Q2M3T9
APPYRRISPLECKLA	CALHM4	86	Q5JW98
RLRIDPSCPQLPYTV	ACSBG1	91	Q96GR2
PLPCRRKPRDYTIKV	ADGRG1	431	Q9Y653
SINPLPKPRRTFRYL	DENND2C	206	Q68D51
GCRPLRPLLNSYQPI	KRTAP26-1	121	Q6PEX3
PCYREPDLSQKPRFL	IGFN1	1146	Q86VF2
APNYPTISRPLICRF	FBLN5	101	Q9UBX5
VFPLKRLKCSYPLLP	FDXACB1	256	Q9BRP7
PRACYRRNKAPALQP	C1orf159	176	Q96HA4
SLKALVLPSPRPYVR	LIG1	811	P18858
PRLFRKLPPRVCVSL	DCAF15	51	Q66K64
TRYPTQPCRFGKLLL	NR2E1	331	Q9Y466
SYQPLCLPLPVCKRL	RGPD1	501	P0DJD0
NPLRYPTIMIPKLCI	OR6K6	156	Q8NGW6
YPTLKPIKSAPVCRN	RP1	926	P56715
LVCREPYSCPRLPKL	RNF186	41	Q9NXI6
CSRQRFLLPRLSPKP	PLEKHF1	186	Q96S99
KVLPPRLNLCPRTSY	ARHGAP20	921	Q9P2F6
LLAPLPPYFSRTLQC	RPUSD3	331	Q6P087
TQYIKSRRGCPVSPP	TRMT44	521	Q8IYL2
RVLCPINYPLSPTRF	TRIM47	451	Q96LD4
KEPILVCPPLRSRAY	MRPL50	46	Q8N5N7
CLLRKTYRAPFLIPI	SLC9C1	1061	Q4G0N8
SLPKSLPLRRPSYTL	SIPA1L1	1621	O43166
CLQVYPTAPKRQRPS	ERVK-10	16	P61580
KSCKPRYPPDSVRLL	SMYD3	91	Q9H7B4
AVLCPPRYPKLAALN	CLIC1	86	O00299
LQKRLPLCYPITQPT	C12orf56	596	Q8IXR9
KPPRLYRESSSCPNI	C15orf62	81	A8K5M9
VPLCRAKPSPSYINL	TSACC	21	Q96A04
NVSRSLRRKYAPPPC	VSIG8	351	P0DPA2
QRDCPNAKPRPILVY	UNC13C	366	Q8NB66
YCPDIPLPRRSISLA	SPIDR	401	Q14159
PIYKLYQPPVTRCLR	SPIDR	621	Q14159
YNPVLRKSCPIPLFV	STPG2	406	Q8N412
PICLYPPTAAKITRC	RNF10	226	Q8N5U6
PPLTCPYSLKARVLL	SEC63	291	Q9UGP8
AQCPAPLSYVPRILL	UGT1A9	181	O60656
RLPRPPLCSRALYSL	TNK1	341	Q13470
LPYQPPALCSLRALS	SNAPC4	1301	Q5SXM2
PCAYTPPSLKAVQRI	PPP1R1B	71	Q9UD71
CYTSLQLRPPQGRIP	SIT1	126	Q9Y3P8
QRVLKYILEPPPCIS	WFDC13	26	Q8IUB5
AQCPAPLSYVPRLLL	UGT1A7	181	Q9HAW7
AQCPAPLSYVPRILL	UGT1A8	181	Q9HAW9
VRLLPPPKNERKFCY	LEG1	156	Q6P5S2
LCVKPDVSVYRIPPR	NECAP1	11	Q8NC96