Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

LRRC8C SLC6A15 SLC25A42 TRPM1 SLC8B1 SLC5A8 SLC7A7 SVOPL MCOLN3 SCN4A ABCB1 ABCB4

3.48e-0811802912GO:0022857
GeneOntologyMolecularFunctiontransporter activity

LRRC8C SLC6A15 SLC25A42 TRPM1 SLC8B1 SLC5A8 SLC7A7 SVOPL MCOLN3 SCN4A ABCB1 ABCB4

9.23e-0812892912GO:0005215
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC6A15 SLC8B1 SLC5A8 MCOLN3 SCN4A

4.37e-06171295GO:0015081
GeneOntologyMolecularFunctionceramide floppase activity

ABCB1 ABCB4

6.10e-063292GO:0099038
GeneOntologyMolecularFunctionsphingolipid floppase activity

ABCB1 ABCB4

1.22e-054292GO:0046623
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC6A15 TRPM1 SLC8B1 SLC5A8 MCOLN3 SCN4A

4.65e-05465296GO:0046873
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC6A15 SLC25A42 SLC8B1 SLC5A8 ABCB1 ABCB4

5.36e-05477296GO:0022804
GeneOntologyMolecularFunctionphosphatidylcholine floppase activity

ABCB1 ABCB4

5.67e-058292GO:0090554
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC6A15 SLC25A42 SLC5A8 SLC7A7 ABCB1

5.85e-05293295GO:0008514
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

LRRC8C SLC6A15 TRPM1 SLC8B1 SLC5A8 MCOLN3 SCN4A

1.10e-04793297GO:0015075
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC6A15 SLC5A8 SLC7A7 ABCB1

2.17e-04207294GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC6A15 SLC5A8 SLC7A7 ABCB1

2.21e-04208294GO:0005342
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC6A15 TRPM1 SLC8B1 SLC5A8 MCOLN3 SCN4A

2.40e-04627296GO:0022890
GeneOntologyMolecularFunctionfloppase activity

ABCB1 ABCB4

2.41e-0416292GO:0140328
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC6A15 TRPM1 SLC8B1 SLC5A8 MCOLN3 SCN4A

3.26e-04664296GO:0008324
GeneOntologyMolecularFunctionsphingolipid transporter activity

ABCB1 ABCB4

3.81e-0420292GO:0046624
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

ABCB1 ABCB4

3.81e-0420292GO:0008525
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC6A15 TRPM1 SLC8B1 SLC5A8 MCOLN3 SCN4A

6.59e-04758296GO:0015318
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCB1 ABCB4

7.52e-0428292GO:0140326
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC6A15 SLC25A42 SLC8B1 SLC5A8

8.39e-04296294GO:0015291
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

LRRC8C TRPM1 SLC5A8 MCOLN3 SCN4A

8.76e-04526295GO:0022803
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC6A15 SLC5A8

1.18e-0335292GO:0005343
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

TRPM1 SLC8B1 MCOLN3

1.34e-03151293GO:0015085
GeneOntologyMolecularFunctionABC-type transporter activity

ABCB1 ABCB4

2.30e-0349292GO:0140359
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCB1 ABCB4

2.48e-0351292GO:0140303
GeneOntologyMolecularFunctionsodium channel activity

MCOLN3 SCN4A

2.58e-0352292GO:0005272
GeneOntologyMolecularFunctionlipid transporter activity

SLC5A8 ABCB1 ABCB4

2.82e-03196293GO:0005319
GeneOntologyMolecularFunctionmonoatomic ion channel activity

LRRC8C TRPM1 MCOLN3 SCN4A

4.15e-03459294GO:0005216
GeneOntologyMolecularFunctionphospholipid transporter activity

ABCB1 ABCB4

5.16e-0374292GO:0005548
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC6A15 SLC5A8

6.15e-0381292GO:0015370
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC25A42 SLC7A7

6.44e-0383292GO:0015101
GeneOntologyMolecularFunctionchannel activity

LRRC8C TRPM1 MCOLN3 SCN4A

6.66e-03525294GO:0015267
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC6A15 SLC8B1 SLC5A8

9.27e-03301293GO:0022853
GeneOntologyMolecularFunctionmonoatomic anion channel activity

LRRC8C MCOLN3

9.77e-03103292GO:0005253
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC6A15 SLC7A7

1.01e-02105292GO:0015171
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCB1 ABCB4

1.09e-02109292GO:0042626
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC6A15 SLC5A8

1.29e-02119292GO:0015294
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TRPM1 MCOLN3 SCN4A

1.32e-02343293GO:0005261
GeneOntologyMolecularFunctioncalcium channel activity

TRPM1 MCOLN3

1.50e-02129292GO:0005262
GeneOntologyMolecularFunctionsymporter activity

SLC6A15 SLC5A8

1.99e-02150292GO:0015293
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

LRRC8C MCOLN3

2.02e-02151292GO:0008509
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

LRRC8C SLC6A15 SLC5A8 SLC7A7 ABCB1

2.46e-06163285GO:1905039
GeneOntologyBiologicalProcessorganic acid transmembrane transport

LRRC8C SLC6A15 SLC5A8 SLC7A7 ABCB1

2.77e-06167285GO:1903825
GeneOntologyBiologicalProcessorganic anion transport

LRRC8C SLC6A15 SLC25A42 SLC5A8 SLC7A7 ABCB1 ABCB4

4.36e-06515287GO:0015711
GeneOntologyBiologicalProcessceramide translocation

ABCB1 ABCB4

5.33e-063282GO:0099040
GeneOntologyBiologicalProcesscarboxylic acid transport

LRRC8C SLC6A15 SLC5A8 SLC7A7 ABCB1 ABCB4

1.55e-05410286GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

LRRC8C SLC6A15 SLC5A8 SLC7A7 ABCB1 ABCB4

1.59e-05412286GO:0015849
GeneOntologyBiologicalProcesssphingolipid translocation

ABCB1 ABCB4

1.77e-055282GO:0099039
GeneOntologyBiologicalProcesssodium ion transport

SLC6A15 SLC8B1 SLC5A8 MCOLN3 SCN4A

3.11e-05275285GO:0006814
GeneOntologyBiologicalProcessorganic cation transport

SLC6A15 SLC25A42 SLC7A7 SCN4A

4.21e-05145284GO:0015695
GeneOntologyBiologicalProcessorganophosphate ester transport

LRRC8C SLC25A42 ABCB1 ABCB4

6.48e-05162284GO:0015748
GeneOntologyBiologicalProcessL-leucine transport

SLC6A15 SLC7A7

7.94e-0510282GO:0015820
GeneOntologyBiologicalProcessmonoatomic anion transport

LRRC8C SLC5A8 MCOLN3 ABCB1

1.04e-04183284GO:0006820
GeneOntologyBiologicalProcessbranched-chain amino acid transport

SLC6A15 SLC7A7

1.60e-0414282GO:0015803
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC6A15 SLC8B1 MCOLN3 SCN4A

1.70e-04208284GO:0035725
GeneOntologyBiologicalProcessceramide transport

ABCB1 ABCB4

2.68e-0418282GO:0035627
GeneOntologyBiologicalProcessmonoatomic ion transport

LRRC8C SLC6A15 TRPM1 SLC8B1 SLC5A8 MCOLN3 SCN4A ABCB1

3.55e-041374288GO:0006811
GeneOntologyBiologicalProcessregulation of AMPA receptor activity

CNIH2 CNIH3

5.23e-0425282GO:2000311
GeneOntologyBiologicalProcessamino acid transmembrane transport

LRRC8C SLC6A15 SLC7A7

5.66e-04120283GO:0003333
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

LRRC8C SLC6A15 TRPM1 SLC8B1 MCOLN3 SCN4A ABCB1

5.75e-041115287GO:0034220
GeneOntologyBiologicalProcessnucleotide transmembrane transport

LRRC8C SLC25A42

8.06e-0431282GO:1901679
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

LRRC8C MCOLN3 ABCB1

1.14e-03153283GO:0098656
GeneOntologyBiologicalProcesspurine-containing compound transmembrane transport

LRRC8C SLC25A42

1.34e-0340282GO:0072530
GeneOntologyBiologicalProcesspurine ribonucleotide transport

LRRC8C SLC25A42

1.34e-0340282GO:0015868
GeneOntologyBiologicalProcessadenine nucleotide transport

LRRC8C SLC25A42

1.48e-0342282GO:0051503
GeneOntologyBiologicalProcesspurine nucleotide transport

LRRC8C SLC25A42

1.62e-0344282GO:0015865
GeneOntologyBiologicalProcessmetal ion transport

SLC6A15 TRPM1 SLC8B1 SLC5A8 MCOLN3 SCN4A

1.92e-031000286GO:0030001
GeneOntologyBiologicalProcessnucleotide transport

LRRC8C SLC25A42

2.09e-0350282GO:0006862
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC6A15 TRPM1 SLC8B1 SLC5A8 MCOLN3 SCN4A

2.10e-031017286GO:0098660
GeneOntologyBiologicalProcessamino acid transport

LRRC8C SLC6A15 SLC7A7

2.29e-03195283GO:0006865
GeneOntologyBiologicalProcessphospholipid translocation

ABCB1 ABCB4

2.52e-0355282GO:0045332
GeneOntologyBiologicalProcessregulation of neurotransmitter receptor activity

CNIH2 CNIH3

2.62e-0356282GO:0099601
GeneOntologyCellularComponentintercellular canaliculus

ABCB1 ABCB4

7.12e-059302GO:0046581
GeneOntologyCellularComponentAMPA glutamate receptor complex

CNIH2 CNIH3

8.45e-0430302GO:0032281
GeneOntologyCellularComponentionotropic glutamate receptor complex

CNIH2 CNIH3

1.90e-0345302GO:0008328
GeneOntologyCellularComponentmonoatomic ion channel complex

LRRC8C CNIH2 CNIH3 SCN4A

1.99e-03378304GO:0034702
GeneOntologyCellularComponentneurotransmitter receptor complex

CNIH2 CNIH3

2.34e-0350302GO:0098878
GeneOntologyCellularComponentER to Golgi transport vesicle membrane

CNIH2 CNIH3

3.80e-0364302GO:0012507
GeneOntologyCellularComponentapical plasma membrane

SLC5A8 PTH1R ABCB1 ABCB4

4.93e-03487304GO:0016324
GeneOntologyCellularComponentdendritic shaft

CNIH2 CNIH3

5.04e-0374302GO:0043198
GeneOntologyCellularComponentendoplasmic reticulum-Golgi intermediate compartment membrane

CNIH2 CNIH3

6.01e-0381302GO:0033116
GeneOntologyCellularComponentbrush border membrane

SLC5A8 PTH1R

6.30e-0383302GO:0031526
GeneOntologyCellularComponenttransmembrane transporter complex

LRRC8C CNIH2 CNIH3 SCN4A

6.34e-03523304GO:1902495
GeneOntologyCellularComponenttransporter complex

LRRC8C CNIH2 CNIH3 SCN4A

7.55e-03550304GO:1990351
GeneOntologyCellularComponentendoplasmic reticulum membrane

LRRC8C TRPM1 BSCL2 CERS1 CNIH2 CNIH3

9.12e-031293306GO:0005789
GeneOntologyCellularComponentreceptor complex

PTH1R CNIH2 CNIH3 CAPRIN2

9.12e-03581304GO:0043235
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

LRRC8C TRPM1 BSCL2 CERS1 CNIH2 CNIH3

9.32e-031299306GO:0098827
GeneOntologyCellularComponentapical part of cell

SLC5A8 PTH1R ABCB1 ABCB4

9.73e-03592304GO:0045177
DomainCornichon_conserved

CNIH2 CNIH3

7.48e-063302IPR033466
DomainCORNICHON

CNIH2 CNIH3

7.48e-063302PS01340
DomainCornichon

CNIH2 CNIH3

1.49e-054302PF03311
DomainCornichon

CNIH2 CNIH3

1.49e-054302IPR003377
DomainCornichon

CNIH2 CNIH3

1.49e-054302SM01398
DomainABC_membrane

ABCB1 ABCB4

6.73e-0424302PF00664
DomainIon_trans_dom

TRPM1 MCOLN3 SCN4A

7.97e-04114303IPR005821
DomainIon_trans

TRPM1 MCOLN3 SCN4A

7.97e-04114303PF00520
DomainABC_TM1F

ABCB1 ABCB4

9.19e-0428302PS50929
DomainABC1_TM_dom

ABCB1 ABCB4

9.19e-0428302IPR011527
DomainABC_transporter_CS

ABCB1 ABCB4

2.06e-0342302IPR017871
DomainABC_TRANSPORTER_2

ABCB1 ABCB4

2.69e-0348302PS50893
DomainABC_tran

ABCB1 ABCB4

2.69e-0348302PF00005
DomainABC_TRANSPORTER_1

ABCB1 ABCB4

2.80e-0349302PS00211
DomainABC_transporter-like

ABCB1 ABCB4

2.91e-0350302IPR003439
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

LRRC8C SLC6A15 TRPM1 SLC8B1 SLC5A8 SLC7A7 MCOLN3 ABCB1 ABCB4

1.38e-06681259MM14985
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

LRRC8C SLC6A15 TRPM1 SLC8B1 SLC5A8 SLC7A7 MCOLN3 ABCB1 ABCB4

2.63e-06736259M27287
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC6A15 SLC8B1 SLC5A8 SLC7A7

3.64e-05108254M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC6A15 SLC8B1 SLC5A8 SLC7A7

3.77e-05109254MM15074
PathwayBIOCARTA_MRP_PATHWAY

ABCB1 ABCB4

4.51e-056252M22078
PathwayWP_PROXIMAL_TUBULE_TRANSPORT

SLC5A8 SLC7A7 ABCB1

1.35e-0457253M39812
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A15 SLC8B1 SLC5A8 SLC7A7

7.58e-04238254MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A15 SLC8B1 SLC5A8 SLC7A7

8.97e-04249254M5988
PathwayREACTOME_TRP_CHANNELS

TRPM1 MCOLN3

1.11e-0328252M27241
PathwayREACTOME_TRP_CHANNELS

TRPM1 MCOLN3

1.11e-0328252MM14943
PathwayWP_DISORDERS_OF_BILE_ACID_SYNTHESIS_AND_BILIARY_TRANSPORT

ABCB1 ABCB4

1.19e-0329252M45551
PathwayWP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY

ABCB1 ABCB4

1.27e-0330252MM15866
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC6A15 SLC7A7

1.45e-0332252MM14957
PathwayREACTOME_CARGO_CONCENTRATION_IN_THE_ER

CNIH2 CNIH3

1.54e-0333252M27591
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC6A15 SLC7A7

1.54e-0333252M188
PathwayBIOCARTA_NUCLEARRS_PATHWAY

ABCB1 ABCB4

1.64e-0334252M16393
PathwayWP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY

ABCB1 ABCB4

1.73e-0335252M39488
PathwayREACTOME_CARGO_CONCENTRATION_IN_THE_ER

CNIH2 CNIH3

1.83e-0336252MM15300
PathwayWP_NUCLEAR_RECEPTORS_METAPATHWAY

SLC6A15 SLC5A8 ABCB1 ABCB4

2.11e-03314254M39428
PathwayKEGG_ABC_TRANSPORTERS

ABCB1 ABCB4

2.73e-0344252M11911
Pubmed

Use of a peptide mimotope to guide the humanization of MRK-16, an anti-P-glycoprotein monoclonal antibody.

ABCB1 ABCB4

7.19e-07230210488067
Pubmed

Role of ABCB1 and ABCB4 in renal and biliary excretion of perfluorooctanoic acid in mice.

ABCB1 ABCB4

7.19e-07230238522903
Pubmed

Localization of the human multiple drug resistance gene, MDR1, to 7q21.1.

ABCB1 ABCB4

7.19e-0723023477522
Pubmed

Multidrug resistance gene expression and ABCB1 SNPs in plasma cell myeloma.

ABCB1 ABCB4

7.19e-07230221705081
Pubmed

The role of different P-glycoproteins in hepatobiliary secretion of fluorescently labeled short-chain phospholipids.

ABCB1 ABCB4

7.19e-07230210552998
Pubmed

Differential Coupling of Binding, ATP Hydrolysis, and Transport of Fluorescent Probes with P-Glycoprotein in Lipid Nanodiscs.

ABCB1 ABCB4

7.19e-07230228441502
Pubmed

Genetic dissection of the function of mammalian P-glycoproteins.

ABCB1 ABCB4

7.19e-0723029196326
Pubmed

Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression.

ABCB1 ABCB4

7.19e-07230218215618
Pubmed

Clinical factors and ABCB1 polymorphisms in prediction of antiepileptic drug response: a prospective cohort study.

ABCB1 ABCB4

7.19e-07230216857572
Pubmed

MDR1 and MDR3 genes and drug resistance to cisplatin of ovarian cancer cells.

ABCB1 ABCB4

7.19e-07230218231753
Pubmed

Effects of cellular, chemical, and pharmacological chaperones on the rescue of a trafficking-defective mutant of the ATP-binding cassette transporter proteins ABCB1/ABCB4.

ABCB1 ABCB4

7.19e-07230222184139
Pubmed

Physical mapping, amplification, and overexpression of the mouse mdr gene family in multidrug-resistant cells.

ABCB1 ABCB4

7.19e-0723021969609
Pubmed

Expression of MDR1 and MDR3 gene products in paclitaxel-, doxorubicin- and vincristine-resistant cell lines.

ABCB1 ABCB4

7.19e-07230224140176
Pubmed

Isolation and expression of a complementary DNA that confers multidrug resistance.

ABCB1 ABCB4

7.19e-0723023022150
Pubmed

Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis.

ABCB1 ABCB4

7.19e-0723029419367
Pubmed

Cell-specific activity of cis-acting regulatory elements in the promoter of the mouse multidrug resistance gene mdr1.

ABCB1 ABCB4

7.19e-0723022248681
Pubmed

ABCB1/4 gallbladder cancer risk variants identified in India also show strong effects in Chileans.

ABCB1 ABCB4

7.19e-07230232058310
Pubmed

Mammalian multidrug-resistance gene: correlation of exon organization with structural domains and duplication of an ancestral gene.

ABCB1 ABCB4

7.19e-0723022570420
Pubmed

MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine.

ABCB1 ABCB4

7.19e-0723028898203
Pubmed

The role of multiple drug resistance proteins in fetal and/or placental protection against teratogen-induced orofacial clefting.

ABCB1 ABCB4

7.19e-07230217440929
Pubmed

Amplification of the murine mdr2 gene and a reconsideration of the structure of the murine mdr gene locus.

ABCB1 ABCB4

7.19e-0723027832992
Pubmed

Mdr P-glycoproteins are not essential for biliary excretion of the hydrophobic heme precursor protoporphyrin in a griseofulvin-induced mouse model of erythropoietic protoporphyria.

ABCB1 ABCB4

7.19e-07230211826402
Pubmed

Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes.

ABCB1 ABCB4

7.19e-0723022473069
Pubmed

Common genetic variation and risk of gallbladder cancer in India: a case-control genome-wide association study.

ABCB1 ABCB4

7.19e-07230228274756
Pubmed

What have we learnt thus far from mice with disrupted P-glycoprotein genes?

ABCB1 ABCB4

7.19e-0723028763339
Pubmed

A missense mutation in ABCB4 gene involved in progressive familial intrahepatic cholestasis type 3 leads to a folding defect that can be rescued by low temperature.

ABCB1 ABCB4

7.19e-07230219185004
Pubmed

Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins.

ABCB1 ABCB4

7.19e-0723023768958
Pubmed

Biliary secretion of alpha-tocopherol and the role of the mdr2 P-glycoprotein in rats and mice.

ABCB1 ABCB4

7.19e-0723029473291
Pubmed

mdr1a-encoded P-glycoprotein is not required for peripheral T cell proliferation, cytokine release, or cytotoxic effector function in mice.

ABCB1 ABCB4

7.19e-07230210453001
Pubmed

The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues.

ABCB1 ABCB4

7.19e-0723022471060
Pubmed

Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse.

ABCB1 ABCB4

2.16e-0633027814632
Pubmed

Immunolocalization of ABC drug transporters in human placenta from normal and gestational diabetic pregnancies.

ABCB1 ABCB4

2.16e-06330225029804
Pubmed

Transbilayer movement of NBD-labeled phospholipids in red blood cell membranes: outward-directed transport by the multidrug resistance protein 1 (MRP1).

ABCB1 ABCB4

2.16e-0633029778357
Pubmed

Selected ABCB1, ABCB4 and ABCC2 polymorphisms do not enhance the risk of drug-induced hepatotoxicity in a Spanish cohort.

ABCB1 ABCB4

2.16e-06330224732756
Pubmed

Structural and functional characterization of the mouse multidrug resistance gene family.

ABCB1 ABCB4

2.16e-0633021980424
Pubmed

Differences between nuclear run-off and mRNA levels for multidrug resistance gene expression in the cephalocaudal axis of the mouse intestine.

ABCB1 ABCB4

2.16e-0633028547326
Pubmed

Intracellular expression of P-170 glycoprotein in peripheral blood mononuclear cell subsets from healthy donors and HIV-infected patients.

ABCB1 ABCB4

2.16e-0633029542318
Pubmed

Upregulation of cornichon transcripts in the dorsolateral prefrontal cortex in schizophrenia.

CNIH2 CNIH3

2.16e-06330223103966
Pubmed

Murine mdr-1, mdr-2, and mdr-3 gene expression: no coinduction with the Cyp1a-1 and Nmo-1 genes in liver by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

ABCB1 ABCB4

4.31e-0643022069718
Pubmed

Temporal/spatial expression and efflux activity of ABC transporter, P-glycoprotein/Abcb1 isoforms and Bcrp/Abcg2 during early murine development.

ABCB1 ABCB4

7.18e-06530216458078
Pubmed

Identification of HAX-1 as a protein that binds bile salt export protein and regulates its abundance in the apical membrane of Madin-Darby canine kidney cells.

ABCB1 ABCB4

7.18e-06530215159385
Pubmed

Cornichon proteins determine the subunit composition of synaptic AMPA receptors.

CNIH2 CNIH3

1.08e-05630223522044
Pubmed

Functional comparison of the effects of TARPs and cornichons on AMPA receptor trafficking and gating.

CNIH2 CNIH3

1.08e-05630220805473
Pubmed

Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways.

SERINC2 PGAP6

2.58e-05930221752829
Pubmed

Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes.

ABCB1 ABCB4

3.22e-051030212068294
Pubmed

A PAI-1 (SERPINE1) polymorphism predicts osteonecrosis in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group.

PTH1R ABCB1

3.94e-051130218285546
Pubmed

Intact lipid rafts regulate HIV-1 Tat protein-induced activation of the Rho signaling and upregulation of P-glycoprotein in brain endothelial cells.

ABCB1 ABCB4

8.57e-051630219794400
Pubmed

Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition.

ABCB1 ABCB4

1.35e-042030221072184
Pubmed

International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.

TRPM1 MCOLN3

2.13e-042530216382100
Pubmed

An introduction to TRP channels.

TRPM1 MCOLN3

2.49e-042730216460286
Pubmed

Amino acid transport across mammalian intestinal and renal epithelia.

SLC6A15 SLC7A7

3.29e-043130218195088
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

TRPM1 MCOLN3

3.74e-043330219834762
Pubmed

Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.

TRPM1 MCOLN3

6.65e-044430219322198
Pubmed

The Oncogenic PRL Protein Causes Acid Addiction of Cells by Stimulating Lysosomal Exocytosis.

SLC5A8 MCOLN3

8.25e-044930232918875
InteractionTMPPE interactions

GPR152 SLC6A15 BSCL2 SCN4A

3.62e-0671304int:TMPPE
InteractionGPR89A interactions

SLC6A15 BSCL2 SLC5A8 SCN4A

2.91e-05120304int:GPR89A
InteractionSIDT2 interactions

LRRC8C SVOPL PTH1R SCN4A

5.31e-05140304int:SIDT2
InteractionABCB4 interactions

ABCB1 ABCB4

5.96e-058302int:ABCB4
InteractionTMEM42 interactions

GPR152 SERINC2 SVOPL

8.69e-0558303int:TMEM42
InteractionPIGO interactions

PTH1R MCOLN3 SCN4A

1.22e-0465303int:PIGO
InteractionMFSD5 interactions

GPR152 BSCL2 SCN4A

2.80e-0486303int:MFSD5
InteractionABHD16A interactions

GPR152 BSCL2 MCOLN3

3.00e-0488303int:ABHD16A
CytobandEnsembl 112 genes in cytogenetic band chr1p22

LRRC8C EPHX4 MCOLN3

9.95e-05137303chr1p22
Cytoband11q13.2

GPR152 CNIH2

4.38e-044730211q13.2
CytobandEnsembl 112 genes in cytogenetic band chr7q21

ABCB1 ABCB4

6.05e-03178302chr7q21
Cytoband14q11.2

SLC7A7 TTC5

6.19e-0318030214q11.2
CytobandEnsembl 112 genes in cytogenetic band chr14q11

SLC7A7 TTC5

1.98e-02332302chr14q11
GeneFamilySolute carriers

SLC6A15 SLC25A42 SLC8B1 SLC5A8 SLC7A7

5.74e-05395205752
GeneFamilyATP binding cassette subfamily B

ABCB1 ABCB4

6.36e-0511202806
GeneFamilyTransient receptor potential cation channels

TRPM1 MCOLN3

4.32e-0428202249
CoexpressionGUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_UP

ABCB1 ABCB4

5.67e-0510302M13976
CoexpressionDESCARTES_ORGANOGENESIS_MELANOCYTES

TRPM1 ADTRP MCOLN3

5.90e-0566303MM3664
CoexpressionGSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_BCELL_UP

TRPM1 PTH1R MCOLN3 CNIH3

7.42e-05198304M5011
CoexpressionGSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_DN

GPR155 TTC5 MCOLN3 ABCB4

7.72e-05200304M8052
CoexpressionGSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY7_DN

TRPM1 SLC7A7 ATRNL1 ABCB4

7.72e-05200304M9370
CoexpressionAtlaskidney single cell_adult_RenalCortexMixed_StemCellamp_k-means-cluster#4_top-relative-expression-ranked_500

BSCL2 SLC5A8 ADTRP SLC7A7 PGAP6 PTH1R

1.03e-05393286gudmap_kidney single cell_adult_RenalCortexMixed_Scamp_k4_500
CoexpressionAtlaskidney_adult_RenalCortexMixed_Std_top-relative-expression-ranked_500

SLC6A15 SLC5A8 ADTRP SLC7A7 PGAP6 PTH1R

1.59e-05424286gudmap_kidney_adult_RenalCortexMixed_Std_500
CoexpressionAtlaskidney_adult_RenalCortexMixed_Std_top-relative-expression-ranked_1000

SLC6A15 SLC5A8 ADTRP SLC7A7 TBC1D8B PGAP6 PTH1R

9.86e-05861287gudmap_kidney_adult_RenalCortexMixed_Std_1000
CoexpressionAtlasBM Top 100 - adrenal gland cortex

MCOLN3 ABCB1 ABCB4

1.06e-0470283BM Top 100 - adrenal gland cortex
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_top-relative-expression-ranked_500

SLC5A8 ADTRP SLC7A7 PGAP6 PTH1R

1.59e-04400285gudmap_kidney_adult_JuxtaGlom_Ren1_500
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#3

GPR155 SLC25A42 SLC8B1 ADTRP EPHX4

1.78e-04410285Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K3
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#1

GPR155 SLC25A42 SLC8B1 ADTRP EPHX4

2.00e-04420285Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#1

GPR155 ADTRP EPHX4

2.31e-0491283Facebase_RNAseq_e10.5_Maxillary Arch_500_K1
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#1

GPR155 SLC25A42 SLC8B1 ADTRP EPHX4

3.13e-04463285Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_500

GPR155 TRPM1 SLC8B1 ADTRP EPHX4

3.99e-04488285Facebase_RNAseq_e10.5_Medial Nasal Eminence_500
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B|GI_small-bowel / Manually curated celltypes from each tissue

SLC6A15 ATRNL1 SCN4A ABCB4

4.77e-061683045535c1b8b7fde7b59a1bc0580cebdfa963aa1c39
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B-Memory_B_cells|GI_small-bowel / Manually curated celltypes from each tissue

SLC6A15 ATRNL1 SCN4A ABCB4

4.77e-061683048e025bb0541746e232b77ac0e31412ae71420c47
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GPR155 SLC25A42 SLC7A7 PTH1R

6.12e-0617930478fae47ec9bff4e0159a86a281e831d7f8ee925a
ToppCellcritical-Lymphoid-NK|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SLC6A15 TRPM1 ATRNL1 MCOLN3

6.26e-061803045abf778395392244daaec876f306ed7e4f388686
ToppCellNS-critical-d_07-13-Lymphoid-NK|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SLC6A15 TRPM1 ATRNL1 MCOLN3

6.54e-06182304dd1c59babf7211362452e3e264009d70004d99f6
ToppCellTCGA-Skin|World / Sample_Type by Project: Shred V9

SLC6A15 TRPM1 CNIH3

1.13e-0414030357d9979bfdcb695869690bf62fa80759ad06eb6c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARSH ADTRP SVOPL

1.13e-04140303e64f6aa57bc069cfe970089bd1c298433bfaf771
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CERS1 MCOLN3 ABCB4

1.35e-04149303a6c24d8f3b5f08587f0a12cd63d166b68ea000c7
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_4|390C / Donor, Lineage, Cell class and subclass (all cells)

GPR155 LRRC8C ADTRP

1.49e-04154303a90c4c45685eae8d21d03479cfd5a23f6ed3ca07
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_2|368C / Donor, Lineage, Cell class and subclass (all cells)

SERINC2 ADTRP SLC7A7

1.67e-04160303ac3f56f8ab8efd11c4b4868a828db05c23ac762f
ToppCellfacs-Heart-RA-18m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERINC2 SLC5A8 ADTRP

1.76e-0416330313557be854878abc1bcdab909b49b8292d064145
ToppCellfacs-Heart-RA-18m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERINC2 SLC5A8 ADTRP

1.76e-041633036c1d1646410e785886d2de103b4b12f73e91edff
ToppCellfacs-Kidney-nan-24m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC5A8 ADTRP PTH1R

1.83e-0416530302a09d0918b103aca21c36b42c5a8a8ebad8686c
ToppCellfacs-Kidney-nan-24m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC5A8 ADTRP PTH1R

1.83e-04165303906321cb5f299d77436fb5540fd8c52d7532beca
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-Exhausted_Tfh|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

LRRC8C ADTRP FAIM2

1.86e-04166303c73fce59256ad501864f44f76cfae2fc33b3777e
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC25A42 EPHX4 PGAP6

1.89e-04167303d1a13d6ada572d8ddb2da95e6e122d2b705fad7f
ToppCelldroplet-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC5A8 ADTRP PTH1R

1.93e-04168303dd48da83c32d41a62f80cd7e5e5c64e42776fa27
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C SERINC2 TRPM1

1.93e-041683032e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SLC6A15 SLC25A42 PTH1R

2.00e-04170303a6fa0cab1fa829ec601fe48306b4c43c83425b04
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SLC6A15 SLC25A42 PTH1R

2.00e-04170303b40255eee45eb18b5a297336d7f3845fd8f8aa3b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A42 SLC7A7 PTH1R

2.03e-04171303f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCelldroplet-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC5A8 ADTRP PTH1R

2.03e-0417130305fcc72df50a380a913821b5781d9621df37d328
ToppCell390C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SERINC2 SLC7A7 ABCB4

2.03e-0417130370963f79711fe6088d6d01b29206b17ab89e5e73
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC5A8 ADTRP PTH1R

2.03e-0417130348fc4eca18b102b5ec5050f758281292ee8e10c6
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Basal_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

GPR155 ADTRP CNIH3

2.07e-04172303b66dbfff5e4f53ca8ece91ff9c5dc66a71f07c63
ToppCell390C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SERINC2 SLC7A7 ABCB4

2.07e-0417230384d16cd7f618c94888920680bdc9e7130d73fd75
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L5-6_FEZF2_ANKRD20A1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC5A8 ADTRP ABCB1

2.07e-04172303ddecdb1a0791296929790f78b49008f51a130f8b
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAIM2 SVOPL MCOLN3

2.14e-041743033f0a5ce074675d57d479fa069385a1b3071e884e
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A15 SLC5A8 MCOLN3

2.17e-04175303182e45f5c02214d6b9f317ff5dc43af8b42de978
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR155 SERINC2 SLC7A7

2.17e-04175303711ace94fa9a763c6ae48171a690953f25deebe4
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC6A15 SERINC2 SLC5A8

2.29e-04178303fb8f8d95f6b08378fb42c4076ee040276faa296f
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC6A15 SERINC2 SLC5A8

2.29e-04178303b89c4d015b44bf538aa39969ef8778877c8023f1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A42 SLC7A7 PTH1R

2.36e-04180303f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHX4 FAIM2 PTH1R

2.36e-04180303e9785ac2806103f725f5a5208495826354ec6e22
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC6A15 ADTRP ABCB1

2.36e-04180303b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A42 SLC7A7 PTH1R

2.36e-041803031363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCellcritical-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ELSPBP1 FAIM2 SVOPL

2.40e-04181303f0d81ae74d3f32979624a94b2ef93774831a7970
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A8 SLC7A7 PTH1R

2.44e-04182303e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCelldroplet-Lung-nan-3m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A15 SERINC2 CAPRIN2

2.44e-04182303cfba75c1ffc39ac76db9e8e27394731942882b30
ToppCelldroplet-Lung-nan-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A15 SERINC2 CAPRIN2

2.44e-041823037e7c7a26460d3003cdf0c0ffb96208a566aa09a7
ToppCelldroplet-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A15 SERINC2 CAPRIN2

2.44e-04182303d836bfdc298ecd3558a973e393a329eb8bd59d79
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A8 SLC7A7 PTH1R

2.44e-0418230357bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCelldroplet-Heart-nan-18m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERINC2 SLC5A8 CNIH3

2.48e-041833031701c8c212f1fdb6e4764375542a203e19753d14
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A42 SLC7A7 PTH1R

2.48e-04183303facd6dbe0851b537d70a899ac7485714ab27d071
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A42 SLC7A7 PTH1R

2.48e-0418330384b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADTRP SLC7A7 PTH1R

2.52e-0418430345577ff91c3b2b303acd97239dde2463ea7a429c
ToppCellCOVID-19-kidney-PCT-S1/S2|kidney / Disease (COVID-19 only), tissue and cell type

GPR155 SLC5A8 PTH1R

2.52e-04184303dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADTRP SLC7A7 PTH1R

2.52e-041843033d7dd193a0826cc7a4e454a29236a16c315e5965
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_3|368C / Donor, Lineage, Cell class and subclass (all cells)

SERINC2 ADTRP SLC7A7

2.60e-04186303ddfadd43efeac3b3e6b7062590cc2b8f2f2db2ab
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A42 SLC7A7 PTH1R

2.60e-041863035784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A42 SLC7A7 PTH1R

2.64e-04187303f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADTRP SVOPL ABCB1

2.64e-041873032d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A42 SLC7A7 PTH1R

2.64e-041873033ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

GPR155 SLC5A8 ABCB1

2.64e-04187303acd305475f3609800af0d7bc68d83ef41228080b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A42 SLC7A7 PTH1R

2.64e-04187303dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

GPR155 SLC8B1 ADTRP

2.68e-04188303b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCellMast_cells|World / lung cells shred on cell class, cell subclass, sample id

ELSPBP1 FAIM2 SVOPL

2.68e-04188303229d24b87e945c4d543d11ac70761e45175ba0e5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A42 SLC7A7 PTH1R

2.68e-04188303f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A42 SLC7A7 PTH1R

2.68e-041883030792432cd4c564dea1102241ea9884f7ced7658c
ToppCell3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ELSPBP1 FAIM2 SVOPL

2.72e-041893031893765b1e3b306f1e133101c28403070a70c3c8
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8B1 SLC5A8 EPHX4

2.72e-041893036f1696871a2994fd5f50b7cf4aa00e6d8054b603
ToppCell3'-Distal_airway-Immune_Myeloid_mast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ELSPBP1 FAIM2 SVOPL

2.72e-0418930396566f84c796d5b2e31f64090555f2b258f0c9f2
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ELSPBP1 FAIM2 SVOPL

2.72e-04189303aba941ba6ce7702418b3f470bde573d123c4aade
ToppCell3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ELSPBP1 FAIM2 SVOPL

2.72e-0418930319b639bc6b35fe1d1079f60c8138aa946a95f3bf
ToppCell368C-Myeloid-Macrophage|368C / Donor, Lineage, Cell class and subclass (all cells)

SERINC2 ADTRP SLC7A7

2.72e-04189303e62355be0d136e2b7c739848022292e9c6af7392
ToppCell3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ELSPBP1 FAIM2 SVOPL

2.72e-04189303b59cc66f7bb9b72895b775fbcf1ec1dc08610969
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_2|356C / Donor, Lineage, Cell class and subclass (all cells)

SERINC2 ADTRP SLC7A7

2.77e-041903034cce4ddb79b7751d0103e10f71156977e0c34439
ToppCellLPS-antiTNF-Endothelial-Endothelial-Vein|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRC8C SERINC2 ABCB1

2.85e-0419230381baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ELSPBP1 FAIM2 SVOPL

2.85e-04192303690cf19e9b0b2ada80097c63eae827529aa5b6f3
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ELSPBP1 FAIM2 SVOPL

2.85e-041923033d6c4c5847ca1e44fa380403d25af45d5b51ee9b
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ELSPBP1 FAIM2 SVOPL

2.85e-04192303e0412964a3ee1bf3c0ef64f9a6f20f7e7835701e
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ELSPBP1 FAIM2 SVOPL

2.85e-04192303b5871247a5f3e970fa05b33fff21bef9d2ab5741
ToppCell390C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SERINC2 ADTRP SLC7A7

2.90e-04193303c9cf5a661294a947d06d53d18d47362c0e0b6ef5
ToppCellcritical-Lymphoid-NK|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SLC6A15 TRPM1 MCOLN3

2.90e-041933036be11fef87af04ee7a3cc223882ccd4077caded9
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_4|343B / Donor, Lineage, Cell class and subclass (all cells)

SERINC2 ADTRP SLC7A7

2.90e-04193303b9dcffd28ca309359fb110fb79de8ce066208ee1
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRC8C SERINC2 ABCB1

2.90e-041933037261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage|367C / Donor, Lineage, Cell class and subclass (all cells)

SERINC2 ADTRP SLC7A7

2.94e-0419430340c91ed945bd5990a0dbf2090d37a660b19aaab2
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

GPR155 SLC8B1 ADTRP

2.99e-04195303d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCellBronchus_Control_(B.)-Immune-TX-TRAM-1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

LRRC8C ADTRP ABCB4

2.99e-04195303dabf667875ed48fdce4f803f5ead39c71a6df42b
ToppCellprimary_visual_cortex-Neuronal|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BSCL2 FAIM2 CNIH2

3.03e-041963038efc2b3a95f57c31be203ac781b2098d4909297f
ToppCellfrontal_cortex-Neuronal|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BSCL2 FAIM2 CNIH2

3.03e-04196303de7d10da862f98894ce47244fbc992f4a12d63bb
ToppCelldistal-Hematologic-Interstitial_Macrophage-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC7A7 MCOLN3 CNIH3

3.03e-04196303e4f40274df940e0996c555082f2bb4f99e5b0881
ToppCell(3)_MNP-(3)_Macrophage_MARCOpos|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

SERINC2 ADTRP SLC7A7

3.03e-04196303a4c9f46ff75dbdd43ad369ceda604fb1650d8a9a
ToppCellCOVID-19_Severe-CD4+_T_naive|COVID-19_Severe / Disease condition and Cell class

GPR155 SLC8B1 ADTRP

3.08e-04197303ac26672bd2cb3bc9a11206d8da203bafec3931f6
ToppCellPSB-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SERINC2 SLC5A8 TBC1D8B

3.12e-04198303e4cbe4032dba0da3fd46817ea9ad86ba9217f747
ToppCellproximal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERINC2 SLC5A8 FAIM2

3.12e-041983033477202c4f702d8f75231b13d4b5216f56d981d7
ToppCellproximal-Epithelial-Goblet-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERINC2 SLC5A8 FAIM2

3.12e-04198303da7b40eb00bb5e454e1cfcd1219dc0d84712592a
ToppCellproximal-Epithelial-Goblet|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERINC2 SLC5A8 FAIM2

3.12e-04198303e7e1c430486a81280abc4a7e7f5bc3713dd20737
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

EPHX4 PTH1R ABCB1

3.17e-04199303236b1417ed0875e98c6ec1ec714003bfce438d65
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC8B1 SLC7A7 SCN4A

3.17e-04199303667b8b47a5b388506e3177b46747267fad8024f6
ToppCellBronchial-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CHIT1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADTRP SLC7A7 MCOLN3

3.17e-0419930354a54ad983503ed515d476882d86b17d97892037
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRRC8C EPHX4 ABCB1

3.17e-0419930363c01e8961f48ed1bed4ab619cacf318cd6de7b9
ToppCellNeuronal-Excitatory-eD(FEZF2)|Neuronal / cells hierarchy compared to all cells using T-Statistic

SLC5A8 ADTRP ABCB1

3.22e-042003031b485ff2435c6732be58cbc9eb2f5c273f9c4bf2
ToppCellBiopsy_Control_(H.)-Immune-Mast_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

ELSPBP1 FAIM2 SVOPL

3.22e-0420030364bf125e0e5652a5a638a6bb32eb109cb0d5e232
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SERINC2 SLC7A7 MCOLN3

3.22e-042003030ca955b71b97571b45e9e89004f1d0bb9fc9e67b
Drug1,9-dideoxyforskolin

ABCB1 ABCB4

1.68e-062302ctd:C047983
DrugNSC652297

SLC5A8 ABCB1

5.03e-063302CID000092781
DrugTechnetium Tc 99m Sestamibi

ABCB1 ABCB4

5.03e-063302ctd:D017256
Drugdimethylaminobenzoate

ABCB1 ABCB4

1.01e-054302CID012241998
DrugAC1NSZ76

SLC5A8 ABCB1

1.67e-055302CID005320215
DrugAC1L2MCS

ABCB1 ABCB4

1.67e-055302CID000023441
Drugv 104

ABCB1 ABCB4

2.51e-056302CID000107262
DrugAC1L99H3

ABCB1 ABCB4

2.51e-056302CID000440540
DrugPIHCA

ABCB1 ABCB4

2.51e-056302CID000108097
DrugC12-NBD-PC

ABCB1 ABCB4

3.51e-057302CID006439314
DrugtBCEU

ABCB1 ABCB4

4.68e-058302CID000164059
DrugT beta-MC

ABCB1 ABCB4

4.68e-058302CID000168408
Drugthiopyrylium

ABCB1 ABCB4

4.68e-058302CID011344401
DrugtXMP

ABCB1 ABCB4

4.68e-058302CID003081384
Drugtri-n-butylmethylammonium

ABCB1 ABCB4

4.68e-058302CID000036208
Drugnicotine glucuronide

ABCB1 ABCB4

4.68e-058302CID003035848
Drugiodoarylazidoprazosin

ABCB1 ABCB4

4.68e-058302CID000115344
Drugamiodarone

SLC5A8 SCN4A ABCB1 ABCB4

5.58e-05160304CID000002156
DrugSo324

ABCB1 ABCB4

6.01e-059302CID000462261
Drugc219

ABCB1 ABCB4

6.01e-059302CID004198643
DrugdiC4PC

ABCB1 ABCB4

7.50e-0510302CID000193375
DrugAC1NN9F1

ABCB1 ABCB4

7.50e-0510302CID000000410
DrugEmd 51921

ABCB1 ABCB4

7.50e-0510302CID000164353
DrugAC1MZ4R5

ABCB1 ABCB4

7.50e-0510302CID003842392
DrugIC-1

ABCB1 ABCB4

1.10e-0412302CID000049829
DrugCytarabine

BSCL2 SLC7A7 PTH1R MCOLN3 CNIH2 ABCB1

1.11e-04598306ctd:D003561
DrugAC1L1AUV

ABCB1 ABCB4

1.30e-0413302CID000051323
DrugS 16020-2

ABCB1 ABCB4

1.30e-0413302CID000177329
DrugI mAb

ABCB1 ABCB4

1.30e-0413302CID003082777
DrugLabetalol

ABCB1 ABCB4

1.30e-0413302ctd:D007741
DrugSuccinylsulfathiazole [116-43-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A

TRPM1 SLC8B1 ADTRP ELSPBP1

1.30e-041993044847_UP
Drugrobinetin

ABCB1 ABCB4

1.51e-0414302CID005281692
DrugPaliperidone Palmitate

ABCB1 ABCB4

1.51e-0414302ctd:D000068882
DrugAC1NSXE4

SLC5A8 ABCB1

1.51e-0414302CID005318881
Drugsodium

SLC6A15 TRPM1 SLC8B1 SLC5A8 SLC7A7 MCOLN3 SCN4A

1.82e-04944307CID000000923
DrugChlorpheniramine

ABCB1 ABCB4

1.99e-0416302ctd:D002744
DrugNSC 284682

ABCB1 ABCB4

1.99e-0416302CID000072518
DrugAC1L18JE

SLC5A8 SLC7A7

2.25e-0417302CID000050153
DrugPgh1

ABCB1 ABCB4

2.25e-0417302CID005283048
Drug8-azido-ADP

ABCB1 ABCB4

2.25e-0417302CID000121934
DrugBasifungin

ABCB1 ABCB4

2.53e-0418302CID000072050
DrugAC1L3X8G

ABCB1 ABCB4

2.53e-0418302CID000123753
DrugY 290

ELSPBP1 ABCB1

2.53e-0418302CID000114729
DrugFluvoxamine

ABCB1 ABCB4

2.53e-0418302ctd:D016666
Drugtetraphenylphosphonium

ABCB1 ABCB4

2.83e-0419302CID000164911
Drugmoxidectin

ABCB1 ABCB4

2.83e-0419302CID009571036
DrugSoybean Oil

ABCB1 ABCB4

3.14e-0420302ctd:D013024
Drugdauricine

SLC5A8 ABCB1

3.47e-0421302CID000073400
DrugNortriptyline

ABCB1 ABCB4

3.47e-0421302ctd:D009661
Drugestradiol-17 beta-glucuronide

ABCB1 ABCB4

3.81e-0422302ctd:C025483
DrugVNP40101M

ABCB1 ABCB4

3.81e-0422302CID003081349
DrugAC1L3C9O

PTH1R ABCB1 ABCB4

4.05e-04110303CID000002521
Drugthioinosinic acid

ABCB1 ABCB4

4.17e-0423302CID003034391
DrugHCFC-123

ABCB1 ABCB4

4.17e-0423302CID000009385
Drugtesaglitazar

SLC6A15 SERINC2 SLC25A42 ADTRP MCOLN3

4.61e-04502305ctd:C501413
Drugprobenecid

SLC5A8 ABCB1 ABCB4

5.61e-04123303CID000004911
Drugilmofosine

ABCB1 ABCB4

5.77e-0427302CID000055008
Drugtariquidar

ABCB1 ABCB4

5.77e-0427302CID000148201
Drugazidopine

ABCB1 ABCB4

6.21e-0428302CID000656406
Drug3 alpha,6 alpha-dihydroxy-5 beta-cholanoic acid

ABCB1 ABCB4

6.67e-0429302CID000006747
Druglinalool

SLC5A8 FAIM2

6.67e-0429302CID000006549
Drugdavidigenin

ABCB1 ABCB4

7.14e-0430302CID000442342
DrugLoratadine

ABCB1 ABCB4

7.14e-0430302ctd:D017336
DrugAC1L9E0Q

ABCB1 ABCB4

7.14e-0430302CID000443095
Drugormosil

SLC6A15 SLC7A7 CNIH3

7.36e-04135303ctd:C510784
Drugcholine

SLC8B1 SLC7A7 ELSPBP1 ABCB4

7.86e-04320304CID000000305
DrugItraconazole

ABCB1 ABCB4

8.12e-0432302ctd:D017964
Drugdodecanethiol

SLC7A7 SCN4A

8.64e-0433302CID000008195
DrugAC1MJ1SO

ABCB1 ABCB4

8.64e-0433302CID003084042
Drug5-hydroxypropafenone

SCN4A ABCB1

9.17e-0434302CID000107927
Drugthioinosine

ABCB1 ABCB4

9.72e-0435302CID000676166
DrugLP T

SLC5A8 TTC5

9.72e-0435302CID000446997
Drugbenzbromarone

ABCB1 ABCB4

1.09e-0337302CID000002333
DrugMIANS

ABCB1 ABCB4

1.09e-0337302CID000119532
Drugacetochlor

TTC5 ABCB1

1.15e-0338302CID000001988
DrugCaLam

ABCB1 ABCB4

1.21e-0339302CID004126474
Drugranolazine

SCN4A ABCB1

1.21e-0339302CID000056959
Drugvalinomycin

ABCB1 ABCB4

1.21e-0339302CID000005649
Drug18alpha-glycyrrhetinic acid

ABCB1 ABCB4

1.27e-0340302ctd:C119129
Drug1,8-cineole

TRPM1 SLC5A8

1.27e-0340302CID000002758
Diseasegallbladder neoplasm

ABCB1 ABCB4

3.11e-059282EFO_0004606
Diseasecystic fibrosis (implicated_via_orthology)

ABCB1 ABCB4

3.11e-059282DOID:1485 (implicated_via_orthology)
DiseaseIntrahepatic cholestasis of pregnancy

ABCB1 ABCB4

1.03e-0416282EFO_0009048
DiseaseHuntington disease, disease progression measurement

TRPM1 ATRNL1

3.72e-0430282EFO_0008336, MONDO_0007739
Diseasemacrophage colony stimulating factor measurement

SLC6A15 CAPRIN2

5.67e-0437282EFO_0008217

Protein segments in the cluster

PeptideGeneStartEntry
ALLAFLFFTSWYSSY

ARSH

201

Q5FYA8
FLVLSWYTFLNYYIS

ADTRP

11

Q96IZ2
IYASYALAFWYGTTL

ABCB1

306

P08183
YWASYAVFFATYLTL

FAIM2

141

Q9BWQ8
SYLVWLFSRIYLYSF

MCOLN3

471

Q8TDD5
LLKSSYYYFFQIPWF

EPHX4

211

Q8IUS5
VFVLLYSSLYSTYLW

GPR155

446

Q7Z3F1
FYYFLWGVSYSSGLF

GPR152

106

Q8TDT2
LSFYSWYGSARLFRF

PGAP6

56

Q9HCN3
LLIYASYALAFWYGS

ABCB4

306

P21439
SWLLCYGFLYLALYA

ATRNL1

41

Q5VV63
FLFYLGSWSYSAYLL

CERS1

106

P27544
GSSWKYSTFSGYLLY

CAPRIN2

1111

Q6IMN6
SYLLGWTTFLLYSYE

ELSPBP1

6

Q96BH3
LLWVSVFLYGSFYYS

BSCL2

41

Q96G97
TLAWALGYLGLYVFY

SLC8B1

226

Q6J4K2
LYYNVIIGWSLFYFS

SLC6A15

156

Q9H2J7
YTSYDTFSWAFLALF

SCN4A

386

P35499
WYSLSYLYFSTVGTL

SLC5A8

516

Q8N695
VLYYTYLNEGFLSLW

SLC25A42

76

Q86VD7
YFSLLTSFAPSYIWF

SVOPL

126

Q8N434
WCKLAFYLLSFFYYL

CNIH2

136

Q6PI25
WCKLAFYLLSFFYYL

CNIH3

136

Q8TBE1
GWLYLSTNFLSFYSF

TBC1D8B

176

Q0IIM8
TFFLYFLATNYYWIL

PTH1R

286

Q03431
LINYYSFSYWFFVGL

SLC7A7

381

Q9UM01
SWYILGNSYLSLYFS

TTC5

181

Q8N0Z6
FWFYTISYLGYLLLF

TRPM1

831

Q7Z4N2
WYAGLFFFTLLFYLL

SERINC2

201

Q96SA4
GLTCLYTLYWLFYRS

LRRC8C

331

Q8TDW0