Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglycosaminoglycan binding

STAB2 PTPRS COL28A1 SUSD5 RTN4R CCN3

3.30e-05268466GO:0005539
GeneOntologyMolecularFunctionchondroitin sulfate binding

PTPRS RTN4R

2.82e-0411462GO:0035374
GeneOntologyMolecularFunctionhemoglobin binding

HP HPR

2.82e-0411462GO:0030492
GeneOntologyCellularComponentspherical high-density lipoprotein particle

HP HPR

1.69e-049462GO:0034366
GeneOntologyCellularComponenthaptoglobin-hemoglobin complex

HP HPR

3.08e-0412462GO:0031838
GeneOntologyCellularComponentextracellular matrix

ADAMTS10 LAMA2 FCGBP COL16A1 ADAMTSL3 COL28A1 CCN3

5.36e-04656467GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

ADAMTS10 LAMA2 FCGBP COL16A1 ADAMTSL3 COL28A1 CCN3

5.46e-04658467GO:0030312
MousePhenohemoglobinemia

HP HPR

2.51e-053412MP:0000332
MousePhenoabnormal axon radial sorting

LAMA2 SBF1

8.35e-055412MP:0020452
MousePhenoenhanced central nervous system regeneration

PTPRS RTN4R

1.25e-046412MP:0030013
DomainHaptoglobin

HP HPR

6.20e-062472IPR008292
DomainMYT1

MYT1L ST18

1.86e-053472PF08474
DomainMyelin_TF

MYT1L ST18

1.86e-053472IPR013681
DomainZnf_C2HC

MYT1L ST18

9.24e-056472IPR002515
Domainzf-C2HC

MYT1L ST18

9.24e-056472PF01530
DomainVWC

MUC19 FCGBP CCN3

1.18e-0438473SM00214
DomainZF_CCHHC

MYT1L ST18

1.29e-047472PS51802
DomainVWF_dom

MUC19 FCGBP CCN3

1.60e-0442473IPR001007
DomainSUSHI

HP SUSD5 HPR

3.77e-0456473PS50923
DomainSushi_SCR_CCP_dom

HP SUSD5 HPR

3.97e-0457473IPR000436
DomainTIL

MUC19 FCGBP

4.03e-0412472PF01826
DomainC8

MUC19 FCGBP

4.03e-0412472PF08742
DomainLINK

STAB2 SUSD5

4.75e-0413472SM00445
DomainUnchr_dom_Cys-rich

MUC19 FCGBP

4.75e-0413472IPR014853
DomainLink_dom

STAB2 SUSD5

4.75e-0413472IPR000538
DomainC8

MUC19 FCGBP

4.75e-0413472SM00832
DomainXlink

STAB2 SUSD5

4.75e-0413472PF00193
DomainLINK_1

STAB2 SUSD5

4.75e-0413472PS01241
DomainLINK_2

STAB2 SUSD5

4.75e-0413472PS50963
DomainTSP_1

ADAMTS10 ADAMTSL3 CCN3

5.34e-0463473PF00090
DomainPLAC

ADAMTS10 ADAMTSL3

5.53e-0414472PF08686
DomainTIL_dom

MUC19 FCGBP

5.53e-0414472IPR002919
DomainuDENN

SBF1 DENND4B

5.53e-0414472SM00800
DomainTSP1

ADAMTS10 ADAMTSL3 CCN3

5.85e-0465473SM00209
DomainTSP1_rpt

ADAMTS10 ADAMTSL3 CCN3

5.85e-0465473IPR000884
DomainTSP1

ADAMTS10 ADAMTSL3 CCN3

5.85e-0465473PS50092
DomainuDENN

SBF1 DENND4B

6.37e-0415472PF03456
DomainUDENN

SBF1 DENND4B

7.27e-0416472PS50946
DomainDDENN

SBF1 DENND4B

7.27e-0416472PS50947
DomainVWD

MUC19 FCGBP

7.27e-0416472SM00216
DomainDENN

SBF1 DENND4B

7.27e-0416472SM00799
DomainVWF_type-D

MUC19 FCGBP

7.27e-0416472IPR001846
DomaindDENN

SBF1 DENND4B

7.27e-0416472SM00801
DomainDENN

SBF1 DENND4B

7.27e-0416472PF02141
DomaindDENN_dom

SBF1 DENND4B

7.27e-0416472IPR005112
DomainuDENN_dom

SBF1 DENND4B

7.27e-0416472IPR005113
DomainVWFD

MUC19 FCGBP

7.27e-0416472PS51233
DomaindDENN

SBF1 DENND4B

7.27e-0416472PF03455
DomainDENN

SBF1 DENND4B

7.27e-0416472PS50211
DomainDENN_dom

SBF1 DENND4B

7.27e-0416472IPR001194
DomainVWD

MUC19 FCGBP

7.27e-0416472PF00094
DomainCTCK_1

MUC19 CCN3

9.24e-0418472PS01185
DomainVWC_out

MUC19 FCGBP

1.03e-0319472SM00215
DomainPLAC

ADAMTS10 ADAMTSL3

1.03e-0319472PS50900
DomainPLAC

ADAMTS10 ADAMTSL3

1.03e-0319472IPR010909
DomainCT

MUC19 CCN3

1.39e-0322472SM00041
DomainPeptidase_M12B_ADAM-TS

ADAMTS10 ADAMTSL3

1.65e-0324472IPR013273
DomainCys_knot_C

MUC19 CCN3

1.79e-0325472IPR006207
DomainCTCK_2

MUC19 CCN3

1.79e-0325472PS01225
DomainEGF_LAM_2

LAMA2 STAB2

2.58e-0330472PS50027
DomainEGF_LAM_1

LAMA2 STAB2

2.58e-0330472PS01248
DomainPeptidase_S1A

CFI HP HPR

2.88e-03113473IPR001314
DomainTRYPSIN_DOM

CFI HP HPR

3.03e-03115473PS50240
DomainTryp_SPc

CFI HP HPR

3.18e-03117473SM00020
DomainTrypsin

CFI HP HPR

3.49e-03121473PF00089
DomainTrypsin_dom

CFI HP HPR

3.49e-03121473IPR001254
DomainEGF_Lam

LAMA2 STAB2

3.50e-0335472SM00180
DomainPeptidase_S1_PA

CFI HP HPR

3.66e-03123473IPR009003
DomainVWFC_2

MUC19 CCN3

4.11e-0338472PS50184
DomainLaminin_EGF

LAMA2 STAB2

4.11e-0338472IPR002049
DomainGrowth_fac_rcpt_

IGF1R STAB2 CCN3

7.08e-03156473IPR009030
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

KMT2C ZNF318 IGF1R AFAP1L2 COL16A1 ZBTB48 SBF1 DENND4B RSF1

3.75e-0768948936543142
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

LAMA2 FCGBP CFI HP PTPRS VNN1

1.45e-0625748616335952
Pubmed

Temporal and age-dependent effects of haptoglobin deletion on intracerebral hemorrhage-induced brain damage and neurobehavioral outcomes.

HP HPR

1.87e-06248230790555
Pubmed

Regulation of haptoglobin gene expression in 3T3-L1 adipocytes by cytokines, catecholamines, and PPARgamma.

HP HPR

1.87e-06248214697247
Pubmed

Haptoglobin genotype is a regulator of reverse cholesterol transport in diabetes in vitro and in vivo.

HP HPR

1.87e-06248217082477
Pubmed

Haptoglobin is degraded by iron in C57BL/6 mice: a possible link with endoplasmic reticulum stress.

HP HPR

1.87e-06248217644369
Pubmed

Nucleotide sequence of the haptoglobin and haptoglobin-related gene pair. The haptoglobin-related gene contains a retrovirus-like element.

HP HPR

1.87e-0624822987228
Pubmed

Haptoglobin Acts as a TLR4 Ligand to Suppress Osteoclastogenesis via the TLR4-IFN-β Axis.

HP HPR

1.87e-06248231076532
Pubmed

Characterization of the mouse haptoglobin gene.

HP HPR

1.87e-0624828288241
Pubmed

Tissue, temporal and inducible expression pattern of haptoglobin in mice.

HP HPR

1.87e-0624829300815
Pubmed

Haptoglobin is required to prevent oxidative stress and muscle atrophy.

HP HPR

1.87e-06248224959824
Pubmed

Obesity-associated hepatosteatosis and impairment of glucose homeostasis are attenuated by haptoglobin deficiency.

HP HPR

1.87e-06248221873550
Pubmed

Pharmacogenomic effect of vitamin E on kidney structure and function in transgenic mice with the haptoglobin 2-2 genotype and diabetes mellitus.

HP HPR

1.87e-06248219176700
Pubmed

Haptoglobin levels in serum of various strains of mice.

HP HPR

1.87e-0624826059653
Pubmed

Aneurysm formation in proinflammatory, transgenic haptoglobin 2-2 mice.

HP HPR

1.87e-06248223096414
Pubmed

Haptoglobin 2-2 genotype determines chronic vasospasm after experimental subarachnoid hemorrhage.

HP HPR

1.87e-06248217962599
Pubmed

Structure and expression of the human haptoglobin locus.

HP HPR

1.87e-0624824018023
Pubmed

Increased renal hypertrophy in diabetic mice genetically modified at the haptoglobin locus.

HP HPR

1.87e-06248215852445
Pubmed

Haptoglobin dampens endotoxin-induced inflammatory effects both in vitro and in vivo.

HP HPR

1.87e-06248215667571
Pubmed

Species-specific changes in regulatory elements of mouse haptoglobin genes.

HP HPR

1.87e-0624828294478
Pubmed

Plasma protein haptoglobin modulates renal iron loading.

HP HPR

1.87e-06248215793279
Pubmed

The acute phase protein haptoglobin regulates host immunity.

HP HPR

1.87e-06248218436583
Pubmed

Correction of HDL dysfunction in individuals with diabetes and the haptoglobin 2-2 genotype.

HP HPR

1.87e-06248218599520
Pubmed

Haptoglobin deficiency facilitates the development of autoimmune inflammation.

HP HPR

1.87e-06248219795414
Pubmed

The haptoglobin 2-2 genotype is associated with increased redox active hemoglobin derived iron in the atherosclerotic plaque.

HP HPR

1.87e-06248219775690
Pubmed

Haptoglobin genotype is a determinant of survival and cardiac remodeling after myocardial infarction in diabetic mice.

HP HPR

1.87e-06248219490627
Pubmed

Haptoglobin is dispensable for haemoglobin uptake by Trypanosoma brucei.

HP HPR

1.87e-06248239114668
Pubmed

Haptoglobin directly affects T cells and suppresses T helper cell type 2 cytokine release.

HP HPR

1.87e-06248212562322
Pubmed

Mouse Heterochromatin Adopts Digital Compaction States without Showing Hallmarks of HP1-Driven Liquid-Liquid Phase Separation.

HP HPR

1.87e-06248232101700
Pubmed

Zonulin as prehaptoglobin2 regulates lung permeability and activates the complement system.

HP HPR

1.87e-06248223564505
Pubmed

Haptoglobin and the Th1/Th2 balance: hints from in vitro and in vivo studies.

HP HPR

1.87e-06248211865978
Pubmed

Haptoglobin, an inflammation-inducible plasma protein.

HP HPR

1.87e-06248211865981
Pubmed

Consequences of haemolysis without haptoglobin.

HP HPR

1.87e-06248211865980
Pubmed

Acute-phase protein haptoglobin is a cell migration factor involved in arterial restructuring.

HP HPR

1.87e-06248212039846
Pubmed

Zonulin transgenic mice show altered gut permeability and increased morbidity/mortality in the DSS colitis model.

HP HPR

1.87e-06248228423466
Pubmed

Haptoglobin polymorphisms in Latin American populations.

HP HPR

1.87e-06248232792581
Pubmed

Transcriptionally active haptoglobin-related (Hpr) gene in hepatoma G2 and leukemia molt-4 cells.

HP HPR

1.87e-0624828945641
Pubmed

Haptoglobin-2 variant increases susceptibility to acute respiratory distress syndrome during sepsis.

HP HPR

1.87e-06248231573976
Pubmed

Poor lysosomal membrane integrity in proximal tubule cells of haptoglobin 2-2 genotype mice with diabetes mellitus.

HP HPR

1.87e-06248222749805
Pubmed

Novel role of zonulin in the pathophysiology of gastro-duodenal transit: a clinical and translational study.

HP HPR

1.87e-06248234789790
Pubmed

Cell type-specific and inflammatory-induced expression of haptoglobin gene in lung.

HP HPR

1.87e-0624827564277
Pubmed

Pharmacogenomic interaction between the Haptoglobin genotype and vitamin E on atherosclerotic plaque progression and stability.

HP HPR

1.87e-06248225618031
Pubmed

A polymorphism in the haptoglobin, haptoglobin related protein locus is associated with risk of human sleeping sickness within Cameroonian populations.

HP HPR

1.87e-06248229077717
Pubmed

Mechanisms regulating repression of haptoglobin production by peroxisome proliferator-activated receptor-gamma ligands in adipocytes.

HP HPR

1.87e-06248219952271
Pubmed

Retinal capillary basement membrane thickness in diabetic mice genetically modified at the haptoglobin locus.

HP HPR

1.87e-06248216742000
Pubmed

Effects of haptoglobin polymorphisms and deficiency on susceptibility to inflammatory bowel disease and on severity of murine colitis.

HP HPR

1.87e-06248221708824
Pubmed

Junctions between genes in the haptoglobin gene cluster of primates.

HP HPR

1.87e-0624821478675
Pubmed

Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature.

HP SUSD5 HPR

4.29e-062348323117660
Pubmed

Zscan10 suppresses osteoclast differentiation by regulating expression of Haptoglobin.

HP HPR

5.59e-06348230771488
Pubmed

A unique form of haptoglobin produced by murine hematopoietic cells supports B-cell survival, differentiation and immune response.

HP HPR

5.59e-06348223548836
Pubmed

Haptoglobin enhances cardiac transplant rejection.

HP HPR

5.59e-06348225801896
Pubmed

Haptoglobin genotype is a determinant of iron, lipid peroxidation, and macrophage accumulation in the atherosclerotic plaque.

HP HPR

5.59e-06348217068284
Pubmed

The haptoglobin beta subunit sequesters HMGB1 toxicity in sterile and infectious inflammation.

HP HPR

5.59e-06348228464519
Pubmed

Complexity of a complex trait locus: HP, HPR, haemoglobin and cholesterol.

HP HPR

5.59e-06348222433445
Pubmed

A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels.

HP HPR

5.59e-06348222403646
Pubmed

Proteomic profiling of mdx-4cv serum reveals highly elevated levels of the inflammation-induced plasma marker haptoglobin in muscular dystrophy.

HP HPR

5.59e-06348228440464
Pubmed

Lack of haptoglobin affects iron transport across duodenum by modulating ferroportin expression.

HP HPR

5.59e-06348217919498
Pubmed

Increased susceptibility in Hp knockout mice during acute hemolysis.

HP HPR

5.59e-0634829731043
Pubmed

Haptoglobin, inflammation, and tumorigenesis in the MIN mouse.

HP HPR

5.59e-06348211865977
Pubmed

Identification of unique glycoisoforms of vitamin D-binding protein and haptoglobin as biomarker candidates in hepatocarcinogenesis of STAM mice.

HP HPR

5.59e-06348230194503
Pubmed

Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca2+ Sensitivity of Insulin Secretion Vesicles.

MYT1L ST18

5.59e-06348229656931
Pubmed

Haptoglobin modifies the hemochromatosis phenotype in mice.

HP HPR

5.59e-06348215613548
Pubmed

miR-139 Functions as An Antioncomir to Repress Glioma Progression Through Targeting IGF-1 R, AMY-1, and PGC-1β.

PPARGC1B IGF1R

5.59e-06348226868851
Pubmed

Genomic structure and chromosomal mapping of the mouse VE-cadherin gene (Cdh5).

HP HPR

5.59e-0634828786117
Pubmed

Ultraviolet-induced cyclobutane pyrimidine dimers are selectively removed from transcriptionally active genes in the epidermis of the hairless mouse.

HP HPR

5.59e-0634828453636
Pubmed

Enhanced splenomegaly and severe liver inflammation in haptoglobin/hemopexin double-null mice after acute hemolysis.

HP HPR

5.59e-06348212393471
Pubmed

Haptoglobin attenuates hemoglobin-induced heme oxygenase-1 in renal proximal tubule cells and kidneys of a mouse model of sickle cell disease.

HP HPR

5.59e-06348225582460
Pubmed

Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes.

HP HPR

5.59e-06348227294203
Pubmed

Phospholipase C gamma-2 (Plcg2) and phospholipase C gamma-1 (Plcg1) map to distinct regions in the human and mouse genomes.

HP HPR

1.12e-0544827774933
Pubmed

IL-22 Controls Iron-Dependent Nutritional Immunity Against Systemic Bacterial Infections.

HP HPR

1.12e-05448228286877
Pubmed

Lack of haptoglobin results in unbalanced VEGFα/angiopoietin-1 expression, intramural hemorrhage and impaired wound healing after myocardial infarction.

HP HPR

1.12e-05448223274064
Pubmed

Myt/NZF family transcription factors regulate neuronal differentiation of P19 cells.

MYT1L ST18

1.12e-05448221540077
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

ADAMTSL3 ST18 PLEKHG3 SUSD5

1.38e-051054849628581
Pubmed

Linkage of the gene for uncoupling protein to esterase-1,2 and haptoglobin in the rat.

HP HPR

1.86e-0554828228167
Pubmed

Hemoglobin and its scavenger protein haptoglobin associate with apoA-1-containing particles and influence the inflammatory properties and function of high density lipoprotein.

HP HPR

1.86e-05548219433579
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

LAMA2 CFI HP HPR CCN3

2.36e-0524848524006456
Pubmed

Spatiotemporal expression pattern of Myt/NZF family zinc finger transcription factors during mouse nervous system development.

MYT1L ST18

2.79e-05648224214099
Pubmed

The GLI-Kruppel family of human genes.

ZBTB48 ZNF875

3.90e-0574822850480
Pubmed

NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans.

PTPRS RTN4R

5.19e-05848222406547
Pubmed

Genetics and evolution of the acute phase proteins in mice.

HP HPR

6.67e-0594823866909
Pubmed

Haemoglobin expression in in vivo murine preimplantation embryos suggests a role in oxygen-regulated gene expression.

HP HPR

6.67e-05948230482269
Pubmed

The cerebrospinal fluid provides a proliferative niche for neural progenitor cells.

FZD1 IGF1R

1.02e-041148221382550
Pubmed

Genome-wide association study of height and body mass index in Australian twin families.

LAMA2 ADAMTSL3

1.22e-041248220397748
Pubmed

Identification of integrin-alpha4, Rb1, and syncytin a as murine placental target genes of the transcription factor GCMa/Gcm1.

CFI VNN1

1.22e-041248218167345
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FZD1 KMT2C IGF1R PNPLA6 SBF1 ESPL1 GBA2 PTPRS

1.24e-04110548835748872
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

LAMA2 ZNF318 RSF1

1.32e-047148333541421
Pubmed

Collagen XXVIII is a distinctive component of the peripheral nervous system nodes of ranvier and surrounds nonmyelinating glial cells.

COL16A1 COL28A1

1.44e-041348220830809
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS10 ADAMTSL3 CCN3

1.55e-047548320637190
Pubmed

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

ADAMTS10 IGF1R ADAMTSL3 ATAD5

1.63e-0419848420881960
Pubmed

Genomic organization and chromosomal mapping of the mouse P-cadherin gene.

HP HPR

1.68e-04144821886768
Pubmed

Proteome-wide characterization of N-glycosylation events by diagonal chromatography.

CFI HP HPR

1.68e-047748316944957
Pubmed

Tissue restricted expression and chromosomal localization of the YB-1 gene encoding a 42 kD nuclear CCAAT binding protein.

HP HPR

1.94e-04154821542575
Pubmed

An interspecific backcross linkage map of mouse chromosome 8.

HP HPR

1.94e-04154821968046
Pubmed

Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse.

MYT1L ST18

2.50e-041748217928203
Pubmed

C/EBPbeta, when expressed from the C/ebpalpha gene locus, can functionally replace C/EBPalpha in liver but not in adipose tissue.

HP HPR

2.50e-041748210982846
Pubmed

Multigenic control of hepatic iron loading in a murine model of hemochromatosis.

HP HPR

2.50e-041748215131800
Pubmed

Gene mapping on mouse chromosome 8 by interspecific crosses: new data on a linkage group conserved on human chromosome 16q.

HP HPR

3.14e-04194822571576
Pubmed

PEBP2 alpha B/mouse AML1 consists of multiple isoforms that possess differential transactivation potentials.

HP HPR

3.14e-04194828164679
Pubmed

CECR2 is involved in spermatogenesis and forms a complex with SNF2H in the testis.

IGF1R RSF1

3.85e-042148222154806
Pubmed

A proteomic analysis of human bile.

FCGBP VNN1

4.23e-042248215084671
GeneFamilyZinc fingers C2H2C-type

MYT1L ST18

1.09e-0533521261
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

HP SUSD5 HPR

1.81e-04573531179
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

SBF1 DENND4B

1.06e-0325352504
GeneFamilyCollagens

COL16A1 COL28A1

3.57e-0346352490
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

ALPK3 ADAMTSL3 PTPRS

3.68e-03161353593
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

AFAP1L2 SBF1 PLEKHG3

7.30e-03206353682
GeneFamilyPHD finger proteins

KMT2C RSF1

1.31e-029035288
CoexpressionYAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1

IGF1R HP HPR CCN3

1.00e-0575474MM868
CoexpressionGSE28783_CTRL_ANTI_MIR_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_DN

MYT1L FZD1 IGF1R PNPLA6 SUSD5

2.84e-05199475M8356
CoexpressionFOURATI_BLOOD_TWINRIX_AGE_65_81YO_RESPONDERS_VS_POOR_RESPONDERS_TRAINING_SET_0DY_NETWORK_INFERENCE_DN

HP HPR

3.14e-055472M41017
CoexpressionHUMMERICH_SKIN_CANCER_PROGRESSION_DN

COL16A1 HP PTPRS HPR

4.72e-05111474MM1111
CoexpressionCADWELL_ATG16L1_TARGETS_UP

CFI HP VNN1 HPR

5.61e-05116474MM1240
CoexpressionLOPEZ_MESOTHELIOMA_SURVIVAL_WORST_VS_BEST_DN

CFI HP

6.57e-057472M7057
CoexpressionLOPEZ_MESOTELIOMA_SURVIVAL_TIME_DN

CFI HP

6.57e-057472M5899
CoexpressionLOPEZ_MESOTHELIOMA_SURVIVAL_OVERALL_UP

CFI HP

8.75e-058472M10759
CoexpressionDESCARTES_ORGANOGENESIS_CONNECTIVE_TISSUE_PROGENITOR

COL16A1 ADAMTSL3 CCN3

1.33e-0455473MM3666
CoexpressionGSE40274_FOXP3_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP

FZD1 LAMA2 WBP1 ESPL1

1.52e-04150474M9146
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

LAMA2 AFAP1L2 ADAMTSL3 PLEKHG3 SUSD5 CCN3

7.52e-08200486b5b5a32925f225610fe25a021a742d6397162863
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

MYT1L LAMA2 AFAP1L2 HUNK ADAMTSL3 PLEKHG3

7.52e-08200486bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCelldroplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FZD1 LAMA2 AFAP1L2 HUNK ADAMTSL3

1.61e-0618448539bb0eb55bdc2cea46e41c7f21d8c5883f14e6bd
ToppCelldroplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FZD1 LAMA2 AFAP1L2 HUNK ADAMTSL3

1.61e-061844854cb5f299dd7413e0be1ad7af817ee614b23a18ae
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

ADAMTS10 LAMA2 COL16A1 ADAMTSL3 PTPRS

1.65e-06185485fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCellCOPD-Epithelial-Mesothelial|Epithelial / Disease state, Lineage and Cell class

PPARGC1B FAM153B CFI HP HPR

1.79e-06188485159d63ecc3653a7449fc6acefd6ef0464845260e
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FZD1 LAMA2 AFAP1L2 HUNK ADAMTSL3

1.88e-061904857e4d80a3a7f83b6a50f1d0fe82fb6c242c39d5b0
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FZD1 LAMA2 AFAP1L2 HUNK ADAMTSL3

1.88e-06190485979b1476fd2692fde977ce56257315fcfc8a01d5
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FZD1 LAMA2 AFAP1L2 HUNK ADAMTSL3

1.88e-061904857fec459cd2ad12c2923a03d098289337c0a4c1d3
ToppCellP07-Mesenchymal-developing_mesenchymal_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FZD1 LAMA2 AFAP1L2 HUNK ADAMTSL3

1.93e-06191485ddbc5f97f2aef19be4ad93db4139876c939b848e
ToppCellP03-Mesenchymal-developing_mesenchymal_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FZD1 LAMA2 AFAP1L2 HUNK ADAMTSL3

1.98e-06192485063e119c4b58957643908f667e6cfd6f7517fd03
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell|Adult / Lineage, Cell type, age group and donor

ADAMTS10 LAMA2 COL16A1 ADAMTSL3 PTPRS

1.98e-06192485d21f0f577156f17c899b08871046a26b88aea011
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal-Mesothelium|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

LSM14A FAM153B CFI HP HPR

2.36e-061994856cfefd81e8a1a883fb4279ac4ab0b298ed2a0817
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 AFAP1L2 ADAMTSL3 SUSD5

2.40e-051564846365b69ede98bc866e996bc52736b00401aacf6f
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLCB2 AFAP1L2 BTBD8 ST18

2.40e-0515648458b9520fce6e259b36c3d59e82b712f5e7729e3e
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CFI GBA2 ST18 PLEKHG3

2.65e-051604848374ae912337947b2cc8d17d5840f306361fe1ff
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FZD1 LAMA2 COL16A1 ADAMTSL3

2.72e-0516148482ed45f144a07856fe92d37426c5f92e259a03a9
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ADAMTS10 NEURL3 ST18 PTPRS

2.72e-0516148478cc5bc488bc47726195a649946d414e6bfabf94
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAMTS10 NEURL3 ST18 PTPRS

2.79e-051624840fa93efc9c005d1e649b3f7069ae8641d6e41ed8
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPARGC1B PLCB2 ESPL1 ST18

2.79e-0516248480619a93c57fe16daf91dc571874ef9ac888953d
ToppCellControl-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

FAM153B CFI HP HPR

3.06e-0516648432ebaefa6c074b28193fff764ee7c2c0e9357e20
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L BTBD8 ST18 PTPRS

3.29e-05169484606aa4ff25380d9470ec116ca86cd20f8b19587a
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L BTBD8 ST18 PTPRS

3.29e-05169484052aae2af5446a0de071d5dda5381b0b9a0ed54d
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PPARGC1B ADAMTSL3 ATAD5 COL28A1

3.52e-0517248403a0aff6b7971093a4347b5ed12546d78374c56f
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FAM153B HP VNN1 HPR

3.60e-051734843d7c281a1a9f183a5a861d1a9c7b50d216535893
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FAM153B HP VNN1 HPR

3.60e-051734843aa90578371039f81b7c6fa873ec70f8f2bc7dfa
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AFAP1L2 ESPL1 ADAMTSL3 COL28A1

3.76e-05175484fa16c6ba08dc0cc22e8cf049db0577811d080df6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 COL16A1 ADAMTSL3 PTPRS

3.76e-05175484795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCellnormal_Lung-Fibroblasts-Mesothelial_cells|normal_Lung / Location, Cell class and cell subclass

FAM153B CFI HP HPR

3.85e-05176484f31d7234053085a82cf9d55aeedd1e04d34789c3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 ADAMTS10 PLCB2 DENND4B

4.02e-05178484ee674e379ee57e40eb2560ff5ed4c13d8db7ed9d
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB2 PNPLA6 CFI ST18

4.02e-0517848409a215a0d6e98e4bb920cabda12af08ff4de3c98
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 ADAMTS10 PLCB2 DENND4B

4.02e-051784846c45bf197d6c1be0ef7d3a644c0062acf1e24e4d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid-macrophage|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 ADAMTS10 PLCB2 DENND4B

4.02e-05178484cd85dcefe94ee742db64b63e105e13532321894a
ToppCellfacs-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 AFAP1L2 HUNK ADAMTSL3

4.11e-051794847078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FZD1 LAMA2 AFAP1L2 ADAMTSL3

4.11e-05179484fa03ec3cc0132f977b4cb28e7b23789732375183
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FZD1 LAMA2 AFAP1L2 ADAMTSL3

4.11e-05179484f5bb4d3a27d56698473219970e764084096cc582
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FZD1 LAMA2 AFAP1L2 ADAMTSL3

4.11e-0517948456db12467b445f2b8ef92af50779eeab10413eb2
ToppCellfacs-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 AFAP1L2 HUNK ADAMTSL3

4.11e-05179484d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCellIPF-Epithelial-Mesothelial|IPF / Disease state, Lineage and Cell class

FAM153B CFI HP HPR

4.20e-051804841fa54bf4dba72866b2295639d991af639341bc08
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFAP1L2 COL16A1 HUNK COL28A1

4.20e-05180484dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 LAMA2 AFAP1L2 ADAMTSL3

4.20e-05180484f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCelldroplet-Lung-nan-18m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 LAMA2 AFAP1L2 ADAMTSL3

4.20e-05180484dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFAP1L2 COL16A1 HUNK COL28A1

4.20e-05180484d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 AFAP1L2 HUNK ADAMTSL3

4.39e-051824849edaccf1154cec92ca9a28e9b1f9075cfd422bfd
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFAP1L2 COL16A1 HUNK ADAMTSL3

4.39e-05182484be9c312a44868d4ee266a64d066feb8c5bce5687
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 AFAP1L2 HUNK ADAMTSL3

4.39e-05182484aba4c06d5d7618ac21b2695bca8e7a1346a91090
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFAP1L2 COL16A1 HUNK ADAMTSL3

4.39e-0518248474dbb706bcaa0f8c922bf3b0424bce5bb27167fa
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFAP1L2 COL16A1 HUNK COL28A1

4.39e-05182484812ff2a50a510b18d865e89465dba1754a08ef61
ToppCellIPF-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

FAM153B CFI HP HPR

4.48e-051834847df20e3172a1220ff427f30181f4f0c3b7fe2d42
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AFAP1L2 COL16A1 HUNK ADAMTSL3

4.58e-051844847128a2be291544d3df3ed6c80f21ddda8437dcba
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AFAP1L2 COL16A1 HUNK ADAMTSL3

4.58e-05184484d14238f7b0b55a4c8d7040bea854bd221a66ac30
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AFAP1L2 COL16A1 HUNK ADAMTSL3

4.58e-0518448455dde9c4eebac2a33788c1ff1d8fe312d150fad4
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D122|Adult / Lineage, Cell type, age group and donor

LAMA2 COL16A1 ADAMTSL3 PTPRS

4.58e-051844842b7e6f91e11c228f0521e099886867d9e998e78d
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AFAP1L2 COL16A1 HUNK ADAMTSL3

4.67e-05185484a6cd90f8f30c7bdf66958cf403e73c193aa32f5e
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AFAP1L2 COL16A1 HUNK ADAMTSL3

4.67e-051854845053f932e2adfcf4d6faaecff2999ac53d8d7aa5
ToppCellCOPD-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

FAM153B CFI HP HPR

4.67e-0518548423579988036fc1925992c31919750f9b3fe9f790
ToppCellHSPCs-Eo/Baso_prog.|World / Lineage and Cell class

PLCB2 IGF1R NEURL3 PTPRS

4.67e-05185484b40ea11f5e536438b400ca5fddfd4559789036bd
ToppCellP15-Mesenchymal-developing_mesenchymal_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FZD1 LAMA2 AFAP1L2 ADAMTSL3

4.77e-05186484db9b67066fc003c7995ec205d15176bf40c97add
ToppCell3'_v3-GI_small-bowel-Lymphocytic_NK-Cycling_NK|GI_small-bowel / Manually curated celltypes from each tissue

FAM153B FCGBP HUNK ESPL1

4.87e-05187484265c690c2921fd201361a0ec8bc4d2a996fbcaf4
ToppCellfacs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WBP1 AFAP1L2 BTBD8 SUSD5

4.87e-05187484f1e9877d859369b862d4a559ec9ab9be74a67a96
ToppCellfacs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WBP1 AFAP1L2 BTBD8 SUSD5

4.87e-051874843ffbd50b49059dcd3e23c5ac01901e4352142446
ToppCelldroplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCB2 GALNS CFI ATAD5

4.87e-0518748414c239af77116d28d511dea754b6150d20488080
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FZD1 LAMA2 AFAP1L2 ADAMTSL3

4.87e-051874848ee3bf885897efd634c3a0567637142a9f55e693
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 COL16A1 ADAMTSL3 PTPRS

4.98e-05188484ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LAMA2 COL16A1 ADAMTSL3 CCN3

5.08e-05189484eccf3d49354a67c94f1ed7c15a98a48a5e8e2ed0
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LAMA2 COL16A1 ADAMTSL3 CCN3

5.08e-0518948440764f461b8aa1d3a2c5a30590b7fb9307d47d09
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FZD1 LAMA2 AFAP1L2 ADAMTSL3

5.08e-05189484ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCelldroplet-Kidney-nan-3m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 COL16A1 ADAMTSL3 COL28A1

5.18e-051904842abeb013bb83c578e67dcb985ba44ca63134950b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 COL16A1 ADAMTSL3 PTPRS

5.18e-05190484efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LAMA2 COL16A1 ADAMTSL3 CCN3

5.29e-051914845271198116343c07202649889057e5774d7fdde3
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 AFAP1L2 COL16A1 ADAMTSL3

5.29e-05191484b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LAMA2 AFAP1L2 HUNK ADAMTSL3

5.29e-051914842ad717b59215ad8d933e9637d363b65d7298e5d4
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 COL16A1 ADAMTSL3 COL28A1

5.29e-05191484d1205aab0937f2becfcd239610e9b78fb8a0c886
ToppCellFibroblast-D_(Pericyte)|World / shred on cell class and cell subclass (v4)

FZD1 AFAP1L2 ADAMTSL3 PLEKHG3

5.40e-051924848c13c351fcc3d88e8c2ffa017e71ff6272cc6fac
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FZD1 LAMA2 AFAP1L2 ADAMTSL3

5.40e-05192484158cc5736f154da1cb3186ffbf186eae10483e48
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FZD1 LAMA2 AFAP1L2 ADAMTSL3

5.40e-05192484f4ff62ac9c53eafbe917706de9af8b2d4bded4d4
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA2 COL16A1 ADAMTSL3 PTPRS

5.51e-05193484261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 COL16A1 ADAMTSL3 PTPRS

5.62e-05194484c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCellIPF-Epithelial-Mesothelial|Epithelial / Disease state, Lineage and Cell class

PPARGC1B FAM153B HP HPR

5.62e-05194484d8a26da856a85e3d001d406e992cb18fdd58baef
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 COL16A1 ADAMTSL3 PTPRS

5.73e-051954843c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell(3)_Chondrocytes-(30)_Chondro|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis

FZD1 LAMA2 STAB2 AFAP1L2

5.73e-05195484f5597d3ed37770c6fa2b339f98a80ac7ecd4f9ff
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

LAMA2 COL16A1 ADAMTSL3 PTPRS

5.73e-05195484aa0add081881d349099d12efca5cdee098038d4e
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA2 COL16A1 ADAMTSL3 PTPRS

5.85e-05196484bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA2 COL16A1 ADAMTSL3 PTPRS

5.85e-051964847d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellBronchial-10x5prime-Stromal-Mesofibroblastic-Mesothelia|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAM153B CFI HP SUSD5

5.97e-0519748426888af95a7cc082a1f1218af35b1f07cb9436ed
ToppCellBronchial-10x5prime-Stromal-Mesofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAM153B CFI HP SUSD5

5.97e-05197484438de7f0d35d81d5f5e41dcef7b2c54b6da03df4
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / Treatment groups by lineage, cell group, cell type

RP9 HUNK ESPL1 ATAD5

5.97e-05197484038fd92750257d43d5e980fd06d77742b543f11a
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PPARGC1B FCGBP ESPL1 VNN1

6.08e-05198484732a43061d75bc5e1cf23f5056b72cd10c926668
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA2 COL16A1 ADAMTSL3 PTPRS

6.08e-051984848f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

LAMA2 COL16A1 ADAMTSL3 PTPRS

6.08e-0519848426e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LAMA2 COL16A1 ADAMTSL3 CCN3

6.20e-0519948495d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

LAMA2 COL16A1 ADAMTSL3 PTPRS

6.20e-051994844bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA2 COL16A1 ADAMTSL3 PTPRS

6.20e-05199484993fa050a095017135a6e723c77cd38b9d782e58
ToppCellTransverse-T_cell-Tfh|T_cell / Region, Cell class and subclass

ZNF318 PNPLA6 ADAMTSL3 PLEKHG3

6.20e-0519948433ffea12b8228e0b5bd8942531c3b21d24224725
ToppCelldistal-mesenchymal-Pericyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FZD1 LAMA2 AFAP1L2 ADAMTSL3

6.20e-05199484000d9b5f5a48e56f0733390adb3d7270c49a4a1a
ToppCellproximal-3-mesenchymal-Pericyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FZD1 LAMA2 AFAP1L2 ADAMTSL3

6.33e-0520048498cbd0f4994e645f70c0bc5ebc1c3a3b28c6b67f
ToppCelldistal-3-mesenchymal-Pericyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FZD1 LAMA2 AFAP1L2 ADAMTSL3

6.33e-05200484911db29f254bb697610e720ba78816e2c7f57933
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA2 COL16A1 ADAMTSL3 PTPRS

6.33e-05200484cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

LAMA2 AFAP1L2 ADAMTSL3 PLEKHG3

6.33e-052004840c648941447c738caf62f2d71e296d6cca492c8b
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte|LPS_only / Treatment groups by lineage, cell group, cell type

LAMA2 ADAMTSL3 SUSD5 CCN3

6.33e-052004848c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ComputationalGenes in the cancer module 576.

PLPBP LSM14A COL16A1 CCN3

2.64e-04110314MODULE_576
ComputationalGenes in the cancer module 503.

PLPBP LSM14A COL16A1 CCN3

2.83e-04112314MODULE_503
DrugNifenazone [2139-47-1]; Down 200; 13uM; PC3; HT_HG-U133A

FZD1 PLPBP GALNS ZBTB48 SBF1 CCN3

3.32e-061954862122_DN
Drugbarium peroxide

HP HPR

4.35e-062482CID000014773
Drugcysteine hydrazide

HP HPR

4.35e-062482CID000042631
Drugisoimide

HP HPR

1.30e-053482CID000443039
Drugdichlorosilylene

HP HPR

2.60e-054482CID000061330
DrugNSC401987

HP HPR

2.60e-054482CID000344857
Drug4-hydroxy-1-phenyl-1-octanone

HP HPR

2.60e-054482CID003025913
DrugNsc1222

RP9 HP HPR

3.43e-0530483CID000219660
DrugS-acetylthioacetic acid

HP HPR

4.33e-055482CID000014485
DrugATX-70

HP HPR

4.33e-055482CID000164378
DrugI acid

HP HPR

4.33e-055482CID000006868
DrugNSC656240

HP HPR

4.33e-055482CID000375903
Drugdihydroquinoline

HP HPR

4.33e-055482CID005231402
Drugricinelaidic acid

PPARGC1B IGF1R HP HPR

4.81e-0595484CID000008839
DrugPirenzepine dihydrochloride [29868-97-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A

FZD1 ZNF318 ZBTB48 SBF1 ATAD5

5.70e-051964857226_DN
DrugH-89, Dihydrochloride; Down 200; 0.5uM; PC3; HT_HG-U133A

PLPBP LSM14A ZNF318 IGF1R PLEKHG3

5.70e-051964856873_DN
Drug7-hydroxy-1-phenyl-1-octanone

HP HPR

6.49e-056482CID000154561
Drugh bu

HP HPR

6.49e-056482CID000446167
Drug4-hydroxy-1-phenyl-1-pentanone

HP HPR

6.49e-056482CID000154889
DrugRU-43044

HP HPR

6.49e-056482CID000188913
Drugmefruside

HP HPR

6.49e-056482CID000004047
Drugadiuvant

HP HPR

6.49e-056482CID000198346
DrugNE-Z

HP HPR

9.08e-057482CID005326929
DrugIAHQ

HP HPR

9.08e-057482CID000073009
Drugalclofenac

HP HPR

9.08e-057482CID000030951
Drug3-(2-carboxyindol-3-yl)propionic acid

HP GBA2 HPR

1.02e-0443483CID000169313
DrugDDOH

HP HPR

1.21e-048482CID000017533
DrugCyclofem

HP HPR

1.21e-048482CID000062995
Drug5-aminouracil

HP HPR

1.21e-048482CID000013611
Drug1-(1-pyrenyl)ethanol

HP HPR

1.21e-048482CID000119118
DrugnI-pI

HP HPR

1.21e-048482CID000125422
Drughydroxypyruvate

GALNS HP HPR

1.25e-0446483CID000000964
DrugNSC406942

PLCB2 RP9 ZBTB48 HP GBA2 HPR RTN4R

1.70e-04565487CID000001115
Drugethyl chloride

HP HPR RTN4R

1.71e-0451483CID000006337
DrugORG 2058

IGF1R HP HPR

1.71e-0451483CID000119086
Drugcopper gluconate

HP HPR

1.94e-0410482CID000010692
Drugpretilachlor

HP HPR

1.94e-0410482CID000091644
Drugsaccharin

PLCB2 ZBTB48 ATAD5

2.02e-0454483CID000005143
DrugGp3G

GALNS HP HPR

2.25e-0456483CID000444841
Drugcalcium formate

HP HPR

2.36e-0411482CID000010997
Drugindolidan

HP HPR

2.36e-0411482CID005284402
DrugCGP71683A

HP HPR

2.36e-0411482CID005312114
DrugCPPP

HP HPR

2.36e-0411482CID000195490
Drugphenazine-1-carboxamide

HP HPR

2.36e-0411482CID000120282
Drugpimaradiene

HP HPR

2.36e-0411482CID000440909
DrugLaevuflex

PPARGC1B GALNS HP GBA2 HPR

2.64e-04272485CID000003426
Drugtanaproget

HP HPR

2.83e-0412482CID004369524
DrugInsulin recombinant

IGF1R CCN3

2.83e-0412482DB00030
Drug2-nitrosopropane

HP HPR

2.83e-0412482CID000079121
Diseasenon-alcoholic fatty liver disease (biomarker_via_orthology)

PPARGC1B IGF1R HP HPR

3.26e-0665464DOID:0080208 (biomarker_via_orthology)
Diseaselevel of izumo sperm-egg fusion protein 4 in blood serum

HP HPR

1.42e-054462OBA_2044625
Diseaselung cancer (biomarker_via_orthology)

HP HPR

1.42e-054462DOID:1324 (biomarker_via_orthology)
Diseaselevel of haptoglobin in blood serum

HP HPR

1.42e-054462OBA_2041919
Diseasehepatocellular adenoma (biomarker_via_orthology)

HP HPR

2.37e-055462DOID:0050868 (biomarker_via_orthology)
Diseaseheparin cofactor 2 measurement

HP HPR

4.97e-057462EFO_0008150
Diseaseacute kidney failure (biomarker_via_orthology)

IGF1R HP HPR

1.20e-0461463DOID:3021 (biomarker_via_orthology)
Diseasepulmonary embolism (biomarker_via_orthology)

HP HPR

1.55e-0412462DOID:9477 (biomarker_via_orthology)
Diseasefrontotemporal dementia, age at onset

ST18 COL28A1

1.83e-0413462EFO_0004847, MONDO_0017276
Diseasebody weights and measures, body height

ADAMTS10 ATAD5

2.46e-0415462EFO_0004324, EFO_0004339
Diseaseleft ventricular structural measurement

ALPK3 IGF1R STAB2

3.55e-0488463EFO_0008205
Diseaseleft ventricular mass

ADAMTS10 IGF1R

3.58e-0418462EFO_0009289
Diseasetype 1 diabetes mellitus (biomarker_via_orthology)

HP HPR

4.00e-0419462DOID:9744 (biomarker_via_orthology)
Diseaseatherosclerosis (biomarker_via_orthology)

HP HPR

4.44e-0420462DOID:1936 (biomarker_via_orthology)
Diseasehaptoglobin measurement

HP HPR

4.90e-0421462EFO_0004640
DiseaseDyslipidemias

HP VNN1

6.42e-0424462C0242339
DiseaseDyslipoproteinemias

HP VNN1

6.42e-0424462C0598784
Diseaseapolipoprotein L1 measurement

HP HPR

6.97e-0425462EFO_0021854
DiseaseLeft ventricular mass to end-diastolic volume ratio

ALPK3 IGF1R

6.97e-0425462EFO_0010556
Diseasechronic kidney disease (biomarker_via_orthology)

HP HPR

8.76e-0428462DOID:784 (biomarker_via_orthology)
Diseaseleft ventricular mass index

ADAMTS10 IGF1R

1.29e-0334462EFO_0009290
DiseaseBladder Neoplasm

LAMA2 KMT2C ESPL1

1.37e-03140463C0005695
DiseaseInflammatory Bowel Diseases

MUC19 VNN1

1.37e-0335462C0021390
DiseaseMalignant neoplasm of urinary bladder

LAMA2 KMT2C ESPL1

1.39e-03141463C0005684

Protein segments in the cluster

PeptideGeneStartEntry
AAPPPVKDCEIEPCK

ATAD5

11

Q96QE3
KKDCELPRSIPACVP

CFI

441

P05156
GEKGDPCEVCPTLPE

COL16A1

501

Q07092
CFPKKPGCLPRSEEA

ALPK3

966

Q96L96
TPDEPCIKCPENLGE

AFAP1L2

581

Q8N4X5
KCDSPTPGDGPEECK

ADAMTS10

1056

Q9H324
ELCLPGPDGKECVVK

PNPLA6

241

Q8IY17
DPKTEPKNCDPKCEQ

LELP1

11

Q5T871
IPKGTFKPPCEDEID

KMT2C

4366

Q8NEZ4
DKLPECEADDGCPKP

HP

81

P00738
GDKLPECEAVCGKPK

HPR

81

P00739
KECGDLCPGTMEEKP

IGF1R

176

P08069
DAKTIDCKPEECPSP

MUC19

8186

Q7Z5P9
ECPSPPTCKTGEKLV

MUC19

8196

Q7Z5P9
DIKDLTVCEPPKPQC

LSM14A

71

Q8ND56
TPPADLIEKCDCPLG

LAMA2

1371

P24043
KLLKACVPGCPAAEP

SBF1

1366

O95248
GCAAEEPPRFIKEPK

PTPRS

26

Q13332
LGEKDCGAPCEPTKV

FZD1

291

Q9UP38
CEKLGKCLTPPESIP

GALNS

501

P34059
PCPDKESDKDLGPRL

ESPL1

1546

Q14674
ERKICECEKGDPGDP

COL28A1

236

Q2UY09
PAPRKVEVPGECCEK

CCN3

156

P48745
KSPEDSRPPKETDCC

GBA2

46

Q9HCG7
GCIPSEECPPELEKK

FCGBP

2641

Q9Y6R7
AGCIPSDKCPPELEK

FCGBP

3841

Q9Y6R7
VKPCCPDIDIFVDGK

BTBD8

201

Q5XKL5
DKNSPPKEEGLCCPP

HUNK

626

P57058
PKAIDCRKCFGAPPE

DENND4B

1481

O75064
ILADDDEPCKKCGLP

RSF1

886

Q96T23
CERDEGSLGKPLCPP

FAM153B

121

P0C7A2
KKPRPSEGDEDCLPA

RPP30

246

P78346
DEEPLGLPKCCQPDA

RTN4R

326

Q9BZR6
LCIKDEEKPCGDPPS

SUSD5

131

O60279
PPGLIKEDETKPEDC

RP9

56

Q8TA86
PGCPVEPDRSSCKKK

PLEKHG3

691

A1L390
RLPAKEDKEPGEDCP

PPARGC1B

241

Q86YN6
PTPDKCAADVKAPLE

PLPBP

256

O94903
PEKRETKCPIPGCDG

ST18

361

O60284
ALKPCPLEDKKPEDC

ZBTB48

196

P10074
RPPTGKKPFDCKECA

ZNF823

156

P16415
DKKPCDTSDPQCPPD

VNN1

141

O95497
KCDKPIPECAALLCP

STAB2

191

Q8WWQ8
PSEAKDKPERACECP

PLCB2

1151

Q00722
VPEPKATPGEECAIC

NEURL3

191

Q96EH8
RKCPLDLCPESKPEI

ZNF875

96

P10072
KLCSPLSEPGDPSKC

ZNF318

2186

Q5VUA4
LCPCPASGEGEPVKE

WBP1

216

Q96G27
EEECEGPKLPTERPC

ADAMTSL3

606

P82987
KEDQEPIRCPVPGCD

MYT1L

946

Q9UL68