Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1

1.74e-0946937GO:0030020
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1

2.81e-05188937GO:0005201
GeneOntologyMolecularFunctionpyrroline-5-carboxylate reductase activity

PYCR1 PYCR2

1.28e-044932GO:0004735
GeneOntologyBiologicalProcessextracellular matrix organization

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 ADAMTS1 NOTCH1

4.73e-05377929GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 ADAMTS1 NOTCH1

4.83e-05378929GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 ADAMTS1 NOTCH1

4.92e-05379929GO:0045229
GeneOntologyCellularComponentcollagen trimer

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 COL20A1

6.43e-0988958GO:0005581
GeneOntologyCellularComponentbasement membrane collagen trimer

COL4A2 COL4A3 COL4A4 COL15A1

2.76e-088954GO:0098651
GeneOntologyCellularComponentbasement membrane

COL4A2 COL4A3 COL4A4 COL7A1 COL15A1 ADAMTS1 ENTPD2

1.40e-06122957GO:0005604
GeneOntologyCellularComponentcollagen type IV trimer

COL4A2 COL4A3 COL4A4

1.80e-066953GO:0005587
GeneOntologyCellularComponentcomplex of collagen trimers

COL4A2 COL4A3 COL4A4 COL7A1

2.26e-0621954GO:0098644
GeneOntologyCellularComponentnetwork-forming collagen trimer

COL4A2 COL4A3 COL4A4

5.01e-068953GO:0098642
GeneOntologyCellularComponentcollagen network

COL4A2 COL4A3 COL4A4

5.01e-068953GO:0098645
GeneOntologyCellularComponentanchoring collagen complex

COL7A1 COL12A1

6.11e-053952GO:0030934
GeneOntologyCellularComponentendoplasmic reticulum lumen

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 COL20A1

1.36e-04332958GO:0005788
GeneOntologyCellularComponentcollagen-containing extracellular matrix

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 ADAMTS1 COL20A1 ENTPD2

1.48e-045309510GO:0062023
GeneOntologyCellularComponentextracellular matrix

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 ADAMTS1 COL20A1 PHOSPHO1 ENTPD2

1.91e-046569511GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 ADAMTS1 COL20A1 PHOSPHO1 ENTPD2

1.96e-046589511GO:0030312
GeneOntologyCellularComponentpostsynaptic density

NRCAM ASIC1 PHB2 ADCY1 RPL23 DLGAP3 NGFR PRKCZ NOTCH1

2.13e-04451959GO:0014069
GeneOntologyCellularComponentasymmetric synapse

NRCAM ASIC1 PHB2 ADCY1 RPL23 DLGAP3 NGFR PRKCZ NOTCH1

3.22e-04477959GO:0032279
GeneOntologyCellularComponentpostsynaptic specialization

NRCAM ASIC1 PHB2 ADCY1 RPL23 DLGAP3 NGFR PRKCZ NOTCH1

4.73e-04503959GO:0099572
GeneOntologyCellularComponentneuron to neuron synapse

NRCAM ASIC1 PHB2 ADCY1 RPL23 DLGAP3 NGFR PRKCZ NOTCH1

6.26e-04523959GO:0098984
GeneOntologyCellularComponentneuromuscular junction

MYH9 DLGAP3 NGFR UNC13C

1.71e-03112954GO:0031594
MousePhenoalbuminuria

COL4A3 COL4A4 MYH9 SMARCAL1 GLIS2

2.93e-0563805MP:0002871
MousePhenouremia

COL4A3 COL4A4 ASPHD1 GTPBP10 TULP3 GLIS2 PWWP3A UNC13C DAAM1 PYCR2 ELMOD1

3.69e-054378011MP:0009644
DomainCollagen

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 COL20A1

8.22e-0985918IPR008160
DomainCollagen

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 COL20A1

8.22e-0985918PF01391
DomainC4

COL4A2 COL4A3 COL4A4

2.21e-066913SM00111
Domain-

COL4A2 COL4A3 COL4A4

2.21e-0669132.170.240.10
DomainCollagen_VI_NC

COL4A2 COL4A3 COL4A4

2.21e-066913IPR001442
DomainC4

COL4A2 COL4A3 COL4A4

2.21e-066913PF01413
DomainNC1_IV

COL4A2 COL4A3 COL4A4

2.21e-066913PS51403
DomainTSPN

COL12A1 COL15A1 COL19A1 COL20A1

4.35e-0623914SM00210
DomainHAD-like_dom

PITPNM2 ATP13A4 PHOSPHO1 ATP2B3 PMM1

4.17e-0579915IPR023214
Domain-

PYCR1 PYCR2

7.02e-0539121.10.3730.10
DomainP5CR_dimer

PYCR1 PYCR2

7.02e-053912PF14748
DomainP5CR_dimer

PYCR1 PYCR2

7.02e-053912IPR029036
DomainP5CR

PYCR1 PYCR2

1.40e-044912PS00521
DomainPyrroline-COOH_reductase

PYCR1 PYCR2

1.40e-044912IPR000304
DomainLaminin_G

COL12A1 COL15A1 COL19A1 COL20A1

1.83e-0458914IPR001791
Domain-

PITPNM2 ATP13A4 PHOSPHO1 PMM1

2.68e-04649143.40.50.1000
DomainProC_N

PYCR1 PYCR2

4.85e-047912IPR028939
DomainF420_oxidored

PYCR1 PYCR2

4.85e-047912PF03807
Domainfn3

COL7A1 COL12A1 NRCAM COL20A1 TYRO3

1.18e-03162915PF00041
DomainCTDL_fold

COL4A2 COL4A3 COL4A4 COL15A1

1.86e-03107914IPR016187
DomainFN3

COL7A1 COL12A1 NRCAM COL20A1 TYRO3

2.11e-03185915SM00060
DomainFH2

FMN1 DAAM1

2.37e-0315912PS51444
DomainFH2_Formin

FMN1 DAAM1

2.37e-0315912IPR015425
DomainFH2

FMN1 DAAM1

2.37e-0315912PF02181
DomainFH2

FMN1 DAAM1

2.37e-0315912SM00498
DomainVWA

COL7A1 COL12A1 COL20A1

2.57e-0356913PF00092
DomainFN3

COL7A1 COL12A1 NRCAM COL20A1 TYRO3

2.90e-03199915PS50853
DomainMyosin_tail_1

MYH9 CGN

3.41e-0318912PF01576
DomainCation_ATPase_N

ATP13A4 ATP2B3

3.41e-0318912PF00690
DomainMyosin_tail

MYH9 CGN

3.41e-0318912IPR002928
DomainCation_ATPase_N

ATP13A4 ATP2B3

3.41e-0318912SM00831
DomainFN3_dom

COL7A1 COL12A1 NRCAM COL20A1 TYRO3

3.57e-03209915IPR003961
DomainATPase_P-typ_cation-transptr_N

ATP13A4 ATP2B3

3.80e-0319912IPR004014
Domain6-PGluconate_DH_C-like

PYCR1 PYCR2

3.80e-0319912IPR008927
DomainConA-like_dom

COL12A1 COL15A1 COL19A1 COL20A1 ALK

4.35e-03219915IPR013320
Domain-

ACACB CDYL

4.64e-03219123.90.226.10
DomainClpP/crotonase-like_dom

ACACB CDYL

4.64e-0321912IPR029045
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 COL20A1

5.01e-1141788MM15538
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 COL20A1

9.18e-1144788M27812
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 COL20A1

1.41e-0961788MM14637
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 COL20A1

3.05e-0967788M26999
PathwayREACTOME_COLLAGEN_FORMATION

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 COL20A1

8.48e-0976788MM14573
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1

1.52e-0853787MM14566
PathwayREACTOME_COLLAGEN_FORMATION

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 COL20A1

3.27e-0890788M631
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1

5.82e-0864787M26953
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1

3.09e-0750786MM14796
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 ADAMTS1

1.01e-06140788M587
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1

1.03e-0661786M27103
PathwayREACTOME_ANCHORING_FIBRIL_FORMATION

COL4A2 COL4A3 COL4A4 COL7A1

1.13e-0615784M27161
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1

3.09e-06114787MM14571
PathwayPID_SYNDECAN_1_PATHWAY

COL4A3 COL4A4 COL7A1 COL12A1 COL15A1

5.23e-0646785M198
PathwayBIOCARTA_NPP1_PATHWAY

COL4A2 COL4A3 COL4A4

1.90e-0510783M22040
PathwayBIOCARTA_NPP1_PATHWAY

COL4A2 COL4A3 COL4A4

1.90e-0510783MM1560
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A2 COL4A3 COL4A4 COL7A1

2.13e-0530784M27216
PathwayBIOCARTA_VITCB_PATHWAY

COL4A2 COL4A3 COL4A4

2.60e-0511783M15422
PathwayBIOCARTA_VITCB_PATHWAY

COL4A2 COL4A3 COL4A4

3.46e-0512783MM1526
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 ADAMTS1 COL20A1

4.00e-05300789M610
PathwayBIOCARTA_ACE2_PATHWAY

COL4A2 COL4A3 COL4A4

4.48e-0513783MM1347
PathwayBIOCARTA_ACE2_PATHWAY

COL4A2 COL4A3 COL4A4

4.48e-0513783M12950
PathwayWP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS

COL4A3 COL4A4 MYH9 SMARCAL1 NOTCH1

4.77e-0572785M39403
PathwayWP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS

COL4A3 COL4A4 MYH9 SMARCAL1 NOTCH1

5.10e-0573785MM15906
PathwayPID_AVB3_INTEGRIN_PATHWAY

COL4A3 COL4A4 COL7A1 COL12A1 COL15A1

5.45e-0574785M160
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A2 COL4A3 COL4A4

5.68e-0514783MM1458
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A2 COL4A3 COL4A4

5.68e-0514783M6487
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A2 COL4A3 COL4A4

7.07e-0515783MM14922
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 COL20A1

8.76e-05258788MM14572
PathwayWP_NEPHROTIC_SYNDROME

COL4A3 COL4A4 MYH9 SMARCAL1

1.09e-0445784M39864
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A2 COL4A3 COL4A4

1.25e-0418783M27164
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A2 COL4A3 COL4A4

1.25e-0418783MM14882
PathwayBIOCARTA_AMI_PATHWAY

COL4A2 COL4A3 COL4A4

1.74e-0420783M15394
PathwayREACTOME_NCAM1_INTERACTIONS

COL4A2 COL4A3 COL4A4

1.74e-0420783MM15061
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A2 COL4A3 COL4A4

2.66e-0423783M15997
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A2 COL4A3 COL4A4

2.66e-0423783MM1427
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL4A2 COL4A3 COL4A4

7.20e-0432783MM14924
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL4A2 COL4A3 COL4A4 COL7A1

8.23e-0476784MM14867
PathwayREACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN

ALG5 GMDS ALG12 PMM1

8.64e-0477784MM15118
PathwayREACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN

ALG5 GMDS ALG12 PMM1

9.52e-0479784M897
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

COL4A2 COL4A3 COL4A4

1.20e-0338783MM14969
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL4A2 COL4A3 COL4A4 COL7A1

1.25e-0385784M16441
PathwayREACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION

COL7A1 MLEC ALG5 GMDS COG5 ALG12 PMM1

1.53e-03307787M894
PathwayREACTOME_NCAM1_INTERACTIONS

COL4A2 COL4A3 COL4A4

1.60e-0342783M7169
PathwayWP_CANCER_PATHWAYS

RAD51 COL4A2 COL4A3 COL4A4 ADCY1 ARHGEF1 PLD2 ALK NOTCH1

1.89e-03507789M48302
Pubmed

Collagen types in various layers of the human aorta and their changes with the atherosclerotic process.

COL4A2 COL4A3 COL4A4

2.24e-0839933089234
Pubmed

Nature and the multiple functions of the 67-kD elastin-/laminin binding protein.

COL4A2 COL4A3 COL4A4

8.93e-0849937827955
Pubmed

In vitro interactions of oxidatively modified LDL with type I, II, III, IV, and V collagen, laminin, fibronectin, and poly-D-lysine.

COL4A2 COL4A3 COL4A4

2.23e-0759939409248
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1

2.95e-0715399725037231
Pubmed

PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.

COL4A2 COL4A3 COL4A4 COL7A1

3.56e-072199427856617
Pubmed

Extracellular matrix of the human optic nerve head.

COL4A2 COL4A3 COL4A4

4.45e-0769932426947
Pubmed

Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome.

COL4A2 COL4A3 COL4A4

4.45e-07699310534397
Pubmed

Developmental distribution of collagen IV isoforms and relevance to ocular diseases.

COL4A2 COL4A3 COL4A4

4.45e-07699319275937
Pubmed

Distribution of basement membrane proteins in normal and fibrotic human liver: collagen type IV, laminin, and fibronectin.

COL4A2 COL4A3 COL4A4

4.45e-0769936988303
Pubmed

Stimulation of extracellular matrix components in the normal brain by invading glioma cells.

COL4A2 COL4A3 COL4A4

4.45e-0769939506531
Pubmed

HIV-1 gp160 protein-macrophage interactions modulate mesangial cell proliferation and matrix synthesis.

COL4A2 COL4A3 COL4A4

4.45e-0769937495302
Pubmed

Angiogenesis and collagen type IV expression in different endothelial cell culture systems.

COL4A2 COL4A3 COL4A4

4.45e-07699323551189
Pubmed

Monoclonal antibody to human basement membrane collagen type IV.

COL4A2 COL4A3 COL4A4

4.45e-0769936811420
Pubmed

Immunolocalization of collagen types, laminin and fibronectin in the normal human pancreas.

COL4A2 COL4A3 COL4A4

4.45e-0769936389236
Pubmed

Collagen IV in the developing lens capsule.

COL4A2 COL4A3 COL4A4

4.45e-07699312225806
Pubmed

A tumor derived motility factor that stimulates cell migration on extracellular matrix.

COL4A2 COL4A3 COL4A4

4.45e-0769939673377
Pubmed

Localization of type IV collagen a 1 to a 6 chains in basement membrane during mouse molar germ development.

COL4A2 COL4A3 COL4A4

4.45e-07699311732842
Pubmed

Regulation of protease nexin-1 target protease specificity by collagen type IV.

COL4A2 COL4A3 COL4A4

7.77e-0779938006028
Pubmed

Corneal cell proteins and ocular surface pathology.

COL4A2 COL4A3 COL4A4

7.77e-07799310416788
Pubmed

Hypoplastic basement membrane of the lens anlage in the inheritable lens aplastic mouse (lap mouse).

COL4A2 COL4A3 COL4A4

7.77e-07799310716744
Pubmed

Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development.

COL4A2 COL4A3 COL4A4

7.77e-0779937521231
Pubmed

Nidogen-1. Expression and ultrastructural localization during the onset of mesoderm formation in the early mouse embryo.

COL4A2 COL4A3 COL4A4

7.77e-07799310639489
Pubmed

Interstitial collagens I, III, and VI sequester and modulate the multifunctional cytokine oncostatin M.

COL4A2 COL4A3 COL4A4

7.77e-07799311711546
Pubmed

Purification, partial characterization of rat kidney hyaluronic acid binding protein and its localization on the cell surface.

COL4A2 COL4A3 COL4A4

7.77e-0779931724753
Pubmed

Appearance and persistence of fibronectin in cartilage. Specific interaction of fibronectin with collagen type II.

COL4A2 COL4A3 COL4A4

1.24e-0689933997552
Pubmed

Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium.

COL4A2 COL4A3 COL4A4

1.24e-06899329422532
Pubmed

Molecular properties of wild-type and mutant betaIG-H3 proteins.

COL4A2 COL4A3 COL4A4

1.24e-06899311867580
Pubmed

Transforming growth factor-beta and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth.

COL4A2 COL4A3 COL4A4

1.24e-06899310382266
Pubmed

Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling.

COL4A2 COL4A3 COL4A4

1.24e-06899311683410
Pubmed

Developmental changes in seminiferous tubule extracellular matrix components of the mouse testis: alpha 3(IV) collagen chain expressed at the initiation of spermatogenesis.

COL4A2 COL4A3 COL4A4

1.86e-0699938562707
Pubmed

Characterization of high affinity binding between laminin and the acute-phase protein, serum amyloid A.

COL4A2 COL4A3 COL4A4

1.86e-0699938995276
Pubmed

Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.

COL4A2 COL4A3 COL4A4

1.86e-06999312101409
Pubmed

Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome.

COL4A2 COL4A3 COL4A4

1.86e-06999310880400
Pubmed

MMP-9 from TNF alpha-stimulated keratinocytes binds to cell membranes and type I collagen: a cause for extended matrix degradation in inflammation?

COL4A2 COL4A3 COL4A4

1.86e-0699939878537
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ATP13A4 ACACB MLEC SMARCAL1 FBF1 GPAT3 PLEKHH1 PYCR1 RBM8A PYCR2 ATP2B3

2.13e-06638991131182584
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

COL4A3 COL7A1 COL12A1 COL15A1 COL19A1 ADAMTS1 NOTCH1

2.46e-0621099716537572
Pubmed

Distribution of fibronectin, type I collagen, type IV collagen, and laminin in the cardiac jelly of the mouse embryonic heart with retinoic acid-induced complete transposition of the great arteries.

COL4A2 COL4A3 COL4A4

2.65e-06109939415455
Pubmed

Interaction between Alzheimer's disease beta A4 precursor protein (APP) and the extracellular matrix: evidence for the participation of heparan sulfate proteoglycans.

COL4A2 COL4A3 COL4A4

2.65e-06109939136074
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

COL4A2 COL4A3 COL4A4 COL7A1 COL15A1

3.22e-067999518757743
Pubmed

Binding of mouse and human fibulin-2 to extracellular matrix ligands.

COL4A2 COL4A3 COL4A4

3.63e-06119937500359
Pubmed

Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development.

COL4A2 COL4A3 COL4A4

3.63e-061199314998921
Pubmed

Interaction of hydroxylated collagen IV with the von hippel-lindau tumor suppressor.

COL4A2 COL4A3 CCT7

3.63e-061199317339318
Pubmed

Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3.

COL4A2 COL4A3 COL4A4

3.63e-06119939731539
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

PITPNM2 MYH9 ACACB MLEC NRCAM PHB2 CCT7 CSDE1 RPL23 DLGAP3 KCNQ5 DAAM1 PYCR2 WNK2

4.30e-061139991436417873
Pubmed

FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex.

COL4A2 COL7A1 COL12A1 COL15A1

4.71e-063999433580754
Pubmed

Muscle progenitor cells failing to respond to positional cues adopt non-myogenic fates in myf-5 null mice.

COL4A2 COL4A3 COL4A4

4.83e-06129938918877
Pubmed

Basement membrane fragility underlies embryonic lethality in fukutin-null mice.

COL4A2 COL4A3 COL4A4

4.83e-061299315837576
Pubmed

Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice.

COL4A2 COL4A3 COL4A4

4.83e-061299316024816
Pubmed

Matrilin-2 interacts with itself and with other extracellular matrix proteins.

COL4A2 COL4A3 COL4A4

4.83e-061299312180907
Pubmed

Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.

COL4A2 COL4A3 COL4A4

6.27e-06139939833687
Pubmed

Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors.

COL4A2 COL4A3 COL4A4

7.96e-061499312878203
Pubmed

Alleviating neuropathic pain hypersensitivity by inhibiting PKMzeta in the anterior cingulate cortex.

ADCY1 PRKCZ

8.02e-06299221127255
Pubmed

Macrophage-released ADAMTS1 promotes muscle stem cell activation.

ADAMTS1 NOTCH1

8.02e-06299228939843
Pubmed

Two genes, COL4A3 and COL4A4 coding for the human alpha3(IV) and alpha4(IV) collagen chains are arranged head-to-head on chromosome 2q36.

COL4A3 COL4A4

8.02e-0629929537506
Pubmed

Identification of mutations in the alpha 3(IV) and alpha 4(IV) collagen genes in autosomal recessive Alport syndrome.

COL4A3 COL4A4

8.02e-0629927987396
Pubmed

The COL4A3 and COL4A4 Digenic Mutations in cis Result in Benign Familial Hematuria in a Large Chinese Family.

COL4A3 COL4A4

8.02e-06299229742505
Pubmed

Is there a dominant-negative effect in individuals with heterozygous disease-causing variants in COL4A3/COL4A4?

COL4A3 COL4A4

8.02e-06299238214412
Pubmed

Formin family proteins in cytoskeletal control.

FMN1 DAAM1

8.02e-06299210631086
Pubmed

Structures of collagen IV globular domains: insight into associated pathologies, folding and network assembly.

COL4A2 COL4A4

8.02e-06299230443360
Pubmed

COL4A3/COL4A4 mutations and features in individuals with autosomal recessive Alport syndrome.

COL4A3 COL4A4

8.02e-06299224052634
Pubmed

Clinico-pathological correlations in 127 patients in 11 large pedigrees, segregating one of three heterozygous mutations in the COL4A3/ COL4A4 genes associated with familial haematuria and significant late progression to proteinuria and chronic kidney disease from focal segmental glomerulosclerosis.

COL4A3 COL4A4

8.02e-06299219357112
Pubmed

Rare hereditary COL4A3/COL4A4 variants may be mistaken for familial focal segmental glomerulosclerosis.

COL4A3 COL4A4

8.02e-06299225229338
Pubmed

Persistent familial hematuria in children and the locus for thin basement membrane nephropathy.

COL4A3 COL4A4

8.02e-06299216235097
Pubmed

ASIC1 promotes differentiation of neuroblastoma by negatively regulating Notch signaling pathway.

ASIC1 NOTCH1

8.02e-06299228030818
Pubmed

Non-muscle myosin heavy chain (MYH9): a new partner fused to ALK in anaplastic large cell lymphoma.

MYH9 ALK

8.02e-06299212800156
Pubmed

Presumed COL4A3/COL4A4 Missense/Synonymous Variants Induce Aberrant Splicing.

COL4A3 COL4A4

8.02e-06299235386907
Pubmed

COL4A3/COL4A4 mutations: from familial hematuria to autosomal-dominant or recessive Alport syndrome.

COL4A3 COL4A4

8.02e-06299212028435
Pubmed

COL4A3/COL4A4 mutations link familial hematuria and focal segmental glomerulosclerosis. glomerular epithelium destruction via basement membrane thinning?

COL4A3 COL4A4

8.02e-06299218661361
Pubmed

Mutation analysis of COL4A3 and COL4A4 genes in a Chinese autosomal-dominant Alport syndrome family.

COL4A3 COL4A4

8.02e-06299228674241
Pubmed

Heterozygous COL4A3/COL4A4 mutations: the hidden part of the iceberg?

COL4A3 COL4A4

8.02e-06299235090027
Pubmed

Complete primary structure of two splice variants of collagen XII, and assignment of alpha 1(XII) collagen (COL12A1), alpha 1(IX) collagen (COL9A1), and alpha 1(XIX) collagen (COL19A1) to human chromosome 6q12-q13.

COL12A1 COL19A1

8.02e-0629929143499
Pubmed

Nine novel COL4A3 and COL4A4 mutations and polymorphisms identified in inherited membrane diseases.

COL4A3 COL4A4

8.02e-06299217216251
Pubmed

Heterozygous Urinary Abnormality-Causing Variants of COL4A3 and COL4A4 Affect Severity of Autosomal Recessive Alport Syndrome.

COL4A3 COL4A4

8.02e-06299235369551
Pubmed

Collagen type IV-related nephropathies in Portugal: pathogenic COL4A3 and COL4A4 mutations and clinical characterization of 25 families.

COL4A3 COL4A4

8.02e-06299225307543
Pubmed

Genetic, Clinical, and Pathologic Backgrounds of Patients with Autosomal Dominant Alport Syndrome.

COL4A3 COL4A4

8.02e-06299227281700
Pubmed

[From Alport syndrome to benign familial hematuria: clinical and genetic aspect].

COL4A3 COL4A4

8.02e-06299216895672
Pubmed

Type-IV collagen related diseases.

COL4A3 COL4A4

8.02e-06299212768082
Pubmed

COL4A3/COL4A4 mutations producing focal segmental glomerulosclerosis and renal failure in thin basement membrane nephropathy.

COL4A3 COL4A4

8.02e-06299217942953
Pubmed

MYH9 facilitates autoregulation of adipose tissue depot development.

MYH9 ADAMTS1

8.02e-06299233986190
Pubmed

Polymorphisms in COL4A3 and COL4A4 genes associated with keratoconus.

COL4A3 COL4A4

8.02e-06299220029656
Pubmed

Whole exome sequencing reveals novel COL4A3 and COL4A4 mutations and resolves diagnosis in Chinese families with kidney disease.

COL4A3 COL4A4

8.02e-06299225381091
Pubmed

Collagen type IV (alpha3-alpha4) nephropathy: from isolated haematuria to renal failure.

COL4A3 COL4A4

8.02e-06299215280517
Pubmed

The genetics of thin basement membrane nephropathy.

COL4A3 COL4A4

8.02e-06299215880327
Pubmed

Polymorphism analysis of COL4A3 and COL4A4 genes in Greek patients with keratoconus.

COL4A3 COL4A4

8.02e-06299225083577
Pubmed

Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly.

COL4A3 COL4A4

8.02e-06299220847057
Pubmed

How to resolve confusion in the clinical setting for the diagnosis of heterozygous COL4A3 or COL4A4 gene variants? Discussion and suggestions from nephrologists.

COL4A3 COL4A4

8.02e-06299232232700
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

MYH9 NRCAM ADCY1 TULP3 CSDE1 TYRO3 PANK2 NOTCH1

8.84e-0635899832460013
Pubmed

Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.

COL4A2 COL4A3 COL4A4

9.93e-061599310625553
Pubmed

Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.

COL4A2 COL4A3 COL4A4

9.93e-06159939264260
Pubmed

Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos.

COL4A2 COL4A3 COL4A4

9.93e-061599310706142
Pubmed

A human MAP kinase interactome.

MYH9 CCDC88B CSDE1 RPL23 ARHGEF1 PRKCZ MAPK6 COG5 WNK2

1.07e-0548699920936779
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1

1.13e-0517599628071719
Pubmed

Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.

COL4A2 COL4A3 COL4A4

1.22e-051699315878328
Pubmed

Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation.

COL4A2 COL4A3 COL4A4

1.77e-05189939160753
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

MYH9 COL12A1 MLEC CCT7 GCDH SMARCAD1 CSDE1 RPL23 NAPRT FUBP1 ARHGEF1 PTRH1 CDYL HARS1

1.85e-051297991433545068
Pubmed

Genetic mapping of 20 novel expressed sequence tags from midgestation mouse embryos suggests chromosomal clustering.

MLEC PEX5 WNK2

2.10e-05199939070936
Pubmed

Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development.

COL4A2 COL4A3 COL4A4

2.10e-051999315689378
Pubmed

Collagen IV diseases: A focus on the glomerular basement membrane in Alport syndrome.

COL4A3 COL4A4

2.40e-05399227576055
Pubmed

Human collagen genes encoding basement membrane alpha 1 (IV) and alpha 2 (IV) chains map to the distal long arm of chromosome 13.

COL4A2 COL4A3

2.40e-0539923025878
Pubmed

A mouse Col4a4 mutation causing Alport glomerulosclerosis with abnormal collagen α3α4α5(IV) trimers.

COL4A3 COL4A4

2.40e-05399224522496
Cytoband6q12-q13

COL12A1 COL19A1

4.68e-05510026q12-q13
Cytoband1q42.12

SDE2 PYCR2

7.03e-041810021q42.12
Cytoband12q24.31

PITPNM2 MLEC DNAH10

7.29e-0480100312q24.31
GeneFamilyCollagens

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 COL20A1

1.86e-1246598490
GeneFamilyCollagens|Collagen proteoglycans

COL12A1 COL15A1

1.04e-045592575
GeneFamilyFibronectin type III domain containing

COL7A1 COL12A1 NRCAM COL20A1 TYRO3

1.74e-04160595555
GeneFamilyHAD Asp-based non-protein phosphatases

PHOSPHO1 PMM1

5.65e-04115921045
GeneFamilyWiskott-Aldrich Syndrome protein family

WASH3P WASH4P

1.22e-031659214
CoexpressionNABA_COLLAGENS

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 COL20A1

4.04e-1243998MM17060
CoexpressionNABA_COLLAGENS

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 COL20A1

4.92e-1244998M3005
CoexpressionHEBERT_MATRISOME_TNBC_LUNG_METASTASIS

COL4A2 COL4A3 COL4A4 COL7A1

1.60e-0623994M48001
CoexpressionNABA_CORE_MATRISOME

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 COL20A1

8.71e-06270998MM17057
CoexpressionNABA_CORE_MATRISOME

COL4A2 COL4A3 COL4A4 COL7A1 COL12A1 COL15A1 COL19A1 COL20A1

9.95e-06275998M5884
CoexpressionNABA_BASEMENT_MEMBRANES

COL4A2 COL4A3 COL4A4 COL15A1

1.58e-0540994M5887
CoexpressionDI_MARTINO_MATRISOME_HIGHLY_PROLIFERATIVE_HNSCC_TUMOR_CELL_DERIVED

COL4A2 COL7A1 COL12A1

3.42e-0517993M47995
CoexpressionDANG_BOUND_BY_MYC

RAD51 COL4A2 PHB2 CCT7 SMARCAD1 TULP3 CSDE1 ALG5 RBM15B PYCR1 GMDS RBM8A HARS1 PYCR2

4.48e-0510619914M15774
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

COL4A2 COL4A3 COL4A4 ATP13A4 MYH9 COL12A1 PRKCZ

1.16e-071701007e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

1.36e-071741007548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCellAT1-AT2_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

1.41e-071751007bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

1.98e-07184100757c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

1.98e-071841007d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

2.06e-0718510071c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellmoderate-Lymphoid-NK|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

COL4A2 COL7A1 COL12A1 COL15A1 ASPHD1 NRCAM ADAMTS1

2.06e-0718510074979a787acbc9b4ca8defe91cc79b674e51af1bf
ToppCellCOPD-Epithelial-ATI|COPD / Disease state, Lineage and Cell class

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

2.13e-071861007df0977f6f48a2d4e11b59971f098b01204242f0f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

2.21e-07187100777f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

2.38e-0718910075a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

2.46e-07190100730b50d183d7649146eb1e79b47ba897355f1998a
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

2.94e-071951007a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

2.94e-07195100768f4cc84b5ae7f4159b780c78e4b66c94211779a
ToppCellAT1_cells|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

2.94e-071951007792d6a49b0a875a00569071183d195287a9925c5
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

2.94e-0719510072a1863f4b9fe73c30b0b1acf9b12fc98ef65040f
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

3.04e-071961007eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

3.15e-0719710078d5097898dd01cedb04cb694cb480c931e08462c
ToppCellBiopsy_IPF-Epithelial-AT1|Biopsy_IPF / Sample group, Lineage and Cell type

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

3.26e-07198100775bdecbe111fededf6082b11de18b84ca308ef6d
ToppCellAT1-AT2_cells|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

3.26e-071981007a5b3617ea2ed4bffba59edcf6284799c2b3bbb29
ToppCellBiopsy_Control_(H.)-Epithelial-AT1|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

3.48e-0720010073a9633f5913f12b6865fc777c84f3f3ba795a78d
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL4A2 COL7A1 ISM2 DLGAP3 PHOSPHO1 ATP2B3

1.28e-06153100665641cc82883716dba0fefb749a30174a63f4da5
ToppCell21-Trachea-Epithelial-Submucosal_gland_basal|Trachea / Age, Tissue, Lineage and Cell class

COL4A2 COL7A1 COL12A1 NRCAM ENTPD2 NGFR

1.61e-0615910064f670b57b8d3b090ea2f1aafe15baf93cb7ef146
ToppCellAT1-AT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

2.29e-061691006815474855a70498a74e52f6583113c63b7267a0c
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL7A1 COL15A1 ADCY1 NAPRT ENTPD2 NGFR

2.37e-0617010068465c3069bbc08705d070927e712b6bc85ac7c5b
ToppCellAT1_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 PRKCZ

2.62e-0617310063afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCellNS-moderate-d_07-13-Lymphoid-NK|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

COL4A2 COL15A1 ASPHD1 NRCAM ADAMTS1 NGFR

2.80e-061751006f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCellAT1_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4 COL12A1 GLIS2 CGN

2.99e-0617710063128b8d04687acee1ac4190b2569d6328b98eaf3
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN

3.19e-0617910061603117b52623663458a977c94bf7f9f6c1114b8
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A3 COL4A4 COL15A1 TYRO3 DLGAP3 ENTPD2

3.29e-06180100639ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCellRA-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL4A2 COL4A3 COL4A4 COL15A1 KCNQ5 DAAM1

3.40e-0618110062b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCellAT1-AT2_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4 COL12A1 CGN PRKCZ

3.40e-061811006ca23ce4f2c7b684d8ddd0e8619b3b696023d75e3
ToppCellCOPD-Epithelial-ATI|World / Disease state, Lineage and Cell class

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

3.51e-061821006e95d946a43b1579af199900bb0e3eacbb9d65300
ToppCellIPF-Epithelial-ATI|World / Disease state, Lineage and Cell class

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

3.62e-06183100631fef35ecf30162662f24d335d8f0cceacc07039
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

3.62e-061831006942530449e9c6583705eeb8f6f12621daea57252
ToppCellIPF-Epithelial-ATI|IPF / Disease state, Lineage and Cell class

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

3.62e-061831006c0a3541c45bd0c587603521f392f42dd86c3c35b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 COL12A1 COL19A1 NRCAM DNAH10 UNC13C

3.74e-0618410062cbed6462fea2622871bb7e49b0df3d984239281
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

3.74e-061841006cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN

3.74e-061841006ca940a4f4970285ed284d5517d142abab0682044
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 COL12A1 COL19A1 NRCAM DNAH10 UNC13C

3.74e-061841006ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 COL12A1 COL19A1 NRCAM DNAH10 UNC13C

3.74e-0618410062b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

3.74e-061841006bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 PRKCZ

3.74e-061841006561592edc3083fad41b91811151b442207c65dd9
ToppCellControl-Epithelial-ATI|World / Disease state, Lineage and Cell class

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

3.85e-0618510060563d5042bb96ecce8446fbf26d05ef7a45e23c5
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

COL4A2 TNK1 COL15A1 ASIC1 TYRO3 NGFR

3.85e-0618510060094f9baddb20214d2a2c166f1637d1a9cf1169a
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

3.98e-06186100609d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellControl-Epithelial-ATI|Control / Disease state, Lineage and Cell class

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN

4.10e-061871006fdd1c57b61ca9392ac27661a82729f37593df63c
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 PRKCZ

4.10e-061871006d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

4.23e-061881006eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCellAT1-AT2_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4 COL12A1 CGN PRKCZ

4.23e-061881006be710bc957118cf426dd71c2d57e6f1b41c9a467
ToppCellmoderate-Lymphoid-NK|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

COL4A2 COL7A1 COL12A1 ASPHD1 NRCAM ADAMTS1

4.36e-06189100622a19365782003c18ec8dddcdbfdaa82c4e330f6
ToppCellrenal_medulla_nuclei-Adult_normal_reference|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

PITPNM2 MYH9 ACACB R3HDM2 FMN1 UNC13C

4.49e-061901006f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL4A2 COL4A3 COL4A4 COL12A1 COL15A1 ADCY1

4.49e-06190100612992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellLAM-Epithelial-AT1|LAM / Condition, Lineage and Cell class

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

4.63e-06191100666875b2ec2c510489407f3e433a90cdf74a15094
ToppCellrenal_papilla_nuclei-Adult_normal_reference|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 COL12A1 ACACB NRCAM UNC13C

4.77e-0619210066c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

COL4A2 MYH9 COL12A1 NRCAM ADAMTS1 KCNQ5

4.92e-061931006000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|356C / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 COL4A3 COL4A4 COL12A1 CGN PRKCZ

5.22e-06195100607a3ef6b0f1201fe2bcb9ea426b8f7a69beb4904
ToppCell(3)_Chondrocytes-(30)_Chondro|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis

BHLHE41 COL4A2 COL12A1 NRCAM ADCY1 WNK2

5.22e-061951006f5597d3ed37770c6fa2b339f98a80ac7ecd4f9ff
ToppCellnormal_Lung-Epithelial_cells-AT1|normal_Lung / Location, Cell class and cell subclass

COL4A2 COL4A3 COL4A4 COL12A1 CGN PRKCZ

5.22e-061951006569d1ebc5a5aa110a2430b096755ae35354040c4
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|356C / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 COL4A3 COL4A4 COL12A1 CGN PRKCZ

5.22e-061951006b65511770ed67f7447847e2187555b362988af45
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

5.37e-0619610066731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCell(7)_Epithelial-I_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

5.37e-061961006150554fa06868d29b0608189862eef6505ba757f
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

5.37e-0619610066856317cd0cdcb88fe54b4ae905d91e13495b1c4
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 PRKCZ

5.53e-061971006c9c968e223e7814cd8d22975d849a31b7e0af7aa
ToppCellAT1_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 CGN

5.53e-06197100680d81be244c94c435accb643449b4ce6a3462c7f
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 PRKCZ

5.53e-061971006734b8db5bb4917c9ce92ed342fe6c22b64b0d3c5
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 COL4A3 COL4A4 ATP13A4 COL12A1 PRKCZ

5.53e-061971006e344455e62b3fe94bb242dc0db58d19a1d3878c7
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-AT1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

5.69e-06198100654228dd9a50616d2022712d162a419ed0327cabd
ToppCellEpithelial_cells-AT1-AT2_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 COL4A4 MYH9 COL12A1 CGN

5.69e-061981006fbc46b20bcd44f2083170aacbc6f5dd00fba685c
ToppCellmedial-2-Epithelial-Alveolar_Epithelial_Type_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

5.86e-061991006456460c761e26ed4b1d88d9bee4d2a7c9bd9d416
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar-AT1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

5.86e-061991006aca81a879ef9c196bd1885eff4c63ffe6c9682b7
ToppCellmedial-Epithelial-Alveolar_Epithelial_Type_1-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

5.86e-0619910065263338242f95c04690d0795749ccc20b0d19f7a
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 COL4A3 COL4A4 COL12A1 ADAMTS1 NGFR

5.86e-0619910063835452e4848d7f7dd8651c17b746b271ef39688
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_1-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

5.86e-061991006c1daa481f88d5281b6b5ea8ec8bb70cc0907d613
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 COL4A3 COL4A4 COL12A1 ADAMTS1 NGFR

5.86e-0619910069c2db0bb94cba71a3cc1827844da090e213e0258
ToppCellmedial-Epithelial-Alveolar_Epithelial_Type_1|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

5.86e-061991006c11365653c69a5dfb37946231f8af05149a61a71
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 COL4A3 COL4A4 COL7A1 ADAMTS1 GMDS

5.86e-0619910062e7f517c0444b4f29ff11c26ab32e9cc0f7e99ef
ToppCellproximal-Epithelial-Alveolar_Epithelial_Type_1-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A2 COL4A3 COL4A4 COL12A1 CGN PRKCZ

6.03e-062001006b652bc73adfdeccbdcd74497ab6e2085e5c95e88
ToppCelldistal-2-Epithelial-Alveolar_Epithelial_Type_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

6.03e-062001006313ec1e53bd738a9cb48dc5b946261156f99f44b
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_alveolar-AT1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

6.03e-0620010063d51aebf626dd4656ab4aac8a20d761b8062c42d
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

6.03e-062001006c6f211bbadd0c9be776c58807249e06764df47dc
ToppCelldistal-3-Epithelial-Alveolar_Epithelial_Type_1|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

6.03e-062001006ff64454a08ae8d4cc6e8f0392558460020844bbc
ToppCellproximal-Epithelial-Alveolar_Epithelial_Type_1|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A2 COL4A3 COL4A4 COL12A1 CGN PRKCZ

6.03e-062001006c1345893e6947ccf9b41282d0e4428dbfb8bcc27
ToppCellBiopsy_Other_PF-Epithelial-AT1|Biopsy_Other_PF / Sample group, Lineage and Cell type

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

6.03e-062001006b746dcc94814bcbca63c71e6451a9c5f084bcfaf
ToppCellproximal-3-Epithelial-Alveolar_Epithelial_Type_1|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A2 COL4A3 COL4A4 COL12A1 CGN PRKCZ

6.03e-06200100651f8fc43c069f2c4e75588d28ae6deb5d7ed2c86
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

6.03e-0620010065f7e8d8b05c90a10313775f9f126eb4ab0fe4f67
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_1-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

6.03e-062001006ccd0edd483728279fe15d64be3a39e8636bf2eeb
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

6.03e-062001006cbe3e107ac16c17687d73ebb04c39d51aba1fa98
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

COL4A3 COL4A4 ATP13A4 COL12A1 CGN PRKCZ

6.03e-062001006e3a80626941363bfc9d97ef906d38c97080aecb1
ToppCellAT1-AT2_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A4 COL12A1 GLIS2 PRKCZ

1.61e-05140100545d52a086ced8d58e01ac51ac4a90338e8649b16
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

COL12A1 DNAH10 PHOSPHO1 LIAT1 COG5

2.25e-051501005ecc4fc94958cf2378dd003966dccba81b3c00f8e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A4 ATP13A4 ISM2 UNC13C

2.32e-05151100516fc903fc71e25717b9908416f0bcd29c0a65a61
ToppCellBasal_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

COL7A1 COL19A1 PHOSPHO1 NGFR UNC13C

2.40e-05152100572499e4d2b374ef5f1621c89d94727ecf4bd4d5d
ToppCellP07-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 COL4A4 ATP13A4 NRCAM NAPRT

2.47e-0515310055501095bcf73080872ae01128f21399f9cfc5dd1
ToppCellnormal_Lung-Endothelial_cells-Tumor_ECs|Endothelial_cells / Location, Cell class and cell subclass

RAD51 COL4A2 COL15A1 MLEC PYCR1

2.55e-051541005afdc385397c7b13c9348eeef95f109f2363057ae
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 DNAH10 ADCY1 UNC13C WNK2

2.88e-051581005f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 DNAH10 ADCY1 UNC13C WNK2

2.88e-0515810058c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

COL4A2 COL4A3 COL4A4 COL12A1 ASIC1

3.06e-05160100558ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCellfacs-Lung-nan-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A3 COL4A4 ATP13A4 CGN PRKCZ

3.65e-05166100511b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCellICU-SEP-Lymphocyte-B-Plasmablast|ICU-SEP / Disease, Lineage and Cell Type

RAD51 BHLHE41 COL4A3 PYCR1 WNK2

3.65e-05166100598ce43e14133418f676f1c88c001add9e28259a7
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A3 COL4A4 ATP13A4 CGN PRKCZ

3.65e-051661005fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
Drugmagnesium

RAD51 COL4A3 SPG7 DNAH10 ADAMTS1 CCT7 TAC4 GTPBP10 ADCY1 RPL23 PHOSPHO1 FUBP1 ENTPD2 NGFR PEX5 PRKCZ PLD2 ATP2B3 ALK PMM1

6.35e-0713259720CID000000888
DrugAC1LAKND

COL4A3 COL7A1 COL12A1 COL19A1 PYCR1

6.75e-0662975CID000470146
DiseaseAlport Syndrome

COL4A3 COL4A4 MYH9

1.33e-074963C1567741
DiseaseAlport Syndrome, X-Linked

COL4A3 COL4A4 MYH9

3.32e-075963C1567742
DiseaseAlport Syndrome, Autosomal Dominant

COL4A3 COL4A4 MYH9

3.32e-075963C1567743
DiseaseAlport Syndrome, Autosomal Recessive

COL4A3 COL4A4 MYH9

3.32e-075963C1567744
DiseaseHemorrhagic hereditary nephritis

COL4A3 MYH9

1.05e-052962C2931861
DiseaseHereditary nephritis

COL4A3 MYH9

1.05e-052962C0027706
Diseasebenign familial hematuria (is_implicated_in)

COL4A3 COL4A4

1.05e-052962DOID:0111365 (is_implicated_in)
DiseaseAlport syndrome, recessive type

COL4A3 COL4A4

1.05e-052962C2931254
DiseaseAlport syndrome, dominant type

COL4A3 COL4A4

1.05e-052962C2931253
DiseaseALPORT SYNDROME 2, AUTOSOMAL RECESSIVE

COL4A3 COL4A4

1.05e-052962C4746745
Diseaseautosomal dominant Alport syndrome (is_implicated_in)

COL4A3 MYH9

1.05e-052962DOID:0110032 (is_implicated_in)
Diseaseautosomal recessive cutis laxa type IIB (implicated_via_orthology)

PYCR1 PYCR2

1.05e-052962DOID:0070137 (implicated_via_orthology)
Diseaseautosomal recessive Alport syndrome (is_implicated_in)

COL4A3 COL4A4

1.05e-052962DOID:0110033 (is_implicated_in)
DiseaseThin basement membrane disease

COL4A3 COL4A4

1.05e-052962C0403440
DiseaseBenign familial hematuria

COL4A3 COL4A4

1.05e-052962cv:C0241908
Diseasecongenital disorder of glycosylation type I (implicated_via_orthology)

ALG5 ALG12 PMM1

1.48e-0515963DOID:0050570 (implicated_via_orthology)
Diseaseautosomal recessive Alport syndrome (implicated_via_orthology)

COL4A3 COL4A4

3.14e-053962DOID:0110033 (implicated_via_orthology)
DiseaseAlport syndrome

COL4A3 COL4A4

3.14e-053962cv:C1567741
DiseaseCollagen IV-related nephropathies

COL4A3 COL4A4

3.14e-053962cv:CN076135
DiseaseRenal glomerular disease

COL4A3 COL4A4 SMARCAL1

5.64e-0523963C0268731
DiseaseGlomerulopathy Assessment

COL4A3 COL4A4 SMARCAL1

5.64e-0523963C4521256
DiseaseHematuria, Benign Familial

COL4A3 COL4A4

6.26e-054962C0241908
Diseasesensory peripheral neuropathy (implicated_via_orthology)

CCT7 HARS1

6.26e-054962DOID:2491 (implicated_via_orthology)
DiseaseHereditary hearing loss and deafness

COL4A3 COL4A4 MYH9 ADCY1 HARS1

1.18e-04146965cv:C0236038
Diseasehypertensive nephropathy

COL4A3 COL4A4

1.56e-046962C0848548
Diseaseend stage renal disease (is_implicated_in)

COL4A3 COL4A4 MYH9

3.25e-0441963DOID:783 (is_implicated_in)
Diseasemyopathy (implicated_via_orthology)

COL4A3 COL4A4 COL15A1

5.19e-0448963DOID:423 (implicated_via_orthology)
Diseasecollagen disease (implicated_via_orthology)

COL4A3 COL4A4

6.77e-0412962DOID:854 (implicated_via_orthology)
DiseaseSmall cell carcinoma of lung

COL4A2 ADCY1 CDYL

7.34e-0454963C0149925
DiseaseTourette syndrome, schizophrenia

PITPNM2 DNAH10

1.55e-0318962EFO_0004895, MONDO_0005090
DiseaseMammary Carcinoma, Human

RAD51 COL7A1 MYH9 NRCAM ADAMTS1 ALK NOTCH1

1.65e-03525967C4704874
DiseaseMammary Neoplasms, Human

RAD51 COL7A1 MYH9 NRCAM ADAMTS1 ALK NOTCH1

1.65e-03525967C1257931
DiseaseMammary Neoplasms

RAD51 COL7A1 MYH9 NRCAM ADAMTS1 ALK NOTCH1

1.69e-03527967C1458155
Diseasetransient cerebral ischemia (biomarker_via_orthology)

ADAMTS1 NGFR NOTCH1 WNK2

1.75e-03157964DOID:224 (biomarker_via_orthology)
DiseaseBreast Carcinoma

RAD51 COL7A1 MYH9 NRCAM ADAMTS1 ALK NOTCH1

1.90e-03538967C0678222
Diseaseintrinsic cardiomyopathy (implicated_via_orthology)

CCT7 DAAM1

2.11e-0321962DOID:0060036 (implicated_via_orthology)
Diseasesex interaction measurement, bilirubin measurement

COL4A2 COL12A1

2.32e-0322962EFO_0004570, EFO_0008343
DiseaseMalignant neoplasm of breast

RAD51 COL7A1 MYH9 COL19A1 NRCAM ADAMTS1 SMARCAL1 PLD2 ALK NOTCH1

2.61e-0310749610C0006142
DiseaseDystonia

KMT2B GCDH PANK2

2.81e-0386963C0013421
Diseaseurinary albumin to creatinine ratio

COL4A4 TYRO3 RASIP1 UNC13C

2.82e-03179964EFO_0007778
Diseasevisual epilepsy (biomarker_via_orthology)

ADAMTS1 NGFR PLD2

3.19e-0390963DOID:11832 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
MRPGGFLGAGQRLSR

PTRH1

1

Q86Y79
RKGGVGMPSRDRNIG

ARHGEF1

301

Q92888
DLESLRNRKMGGRPG

CCDC61

91

Q9Y6R9
GDDPKTDFRGMGLLG

ELMOD1

166

Q8N336
MEGGKGPRLRDFLSG

CCDC88B

1

A6NC98
GSKGERGRPGKDAMG

COL4A3

401

Q01955
APKRMKLDSRGGGSG

BHLHE41

276

Q9C0J9
GGDRLAFMKGAPERV

ATP13A4

616

Q4VNC1
MLRGAPGLGLTARKG

BHLHA9

1

Q7RTU4
RGKGGAIRMGIFSSR

ALG5

141

Q9Y673
MTAAETGRGKPRLGG

GUSBP11

1

Q6P575
GEKGMSGLPGDRGLR

COL4A4

936

P53420
LKGEEGIMGFPGLRG

COL4A2

291

P08572
PRGPDNSMGFGAERK

CSDE1

776

O75534
VDGMGRFGRSLKVGL

ADCK5

81

Q3MIX3
VIRMPDGGFRLFSKG

ATP2B3

586

Q16720
MAGKGSSGRRPLLLG

ALG12

1

Q9BV10
KGGSAGRISRPGMAL

R3HDM2

366

Q9Y2K5
MLSGERKEGGSPRFG

RASIP1

1

Q5U651
AKMRGFPLGGPDRRL

RBM15B

471

Q8NDT2
KGRGFGSEEGSRARM

RBM8A

36

Q9Y5S9
LPIDRGGGEGKAMYI

RAD51

146

Q06609
PEGFGRRKLGSDMGN

ADAMTS1

6

Q9UHI8
GRGGRESAPLMGKDK

FMN1

181

Q68DA7
DALADGGVKMGLPRR

PYCR1

186

P32322
RIGFPLMIKASEGGG

ACACB

446

O00763
MLAKGAEEGRSGGPR

LINC01548

1

A6NM66
AKPEMAALGGGGRLA

NOTCH1

2251

P46531
ARGSGDGEMGKPRNV

GMDS

11

O60547
LMQMRFDGRLGFPGG

NUDT16

46

Q96DE0
GSRSFFGLKGLMPGT

NRCAM

1116

Q92823
KVPDGMVGFIIGRGG

FUBP1

106

Q96AE4
PLEGRVGRASDYGMK

MLEC

71

Q14165
MKEGRGSFSVERGPR

ASPHD1

1

Q5U4P2
VPEMEKRGGGSVGFL

DHRS4L1

156

P0CG22
RLGSGMKDVESGRGR

KCNQ5

31

Q9NR82
RLGGFRGAPGLLMAV

DCAF4L2

371

Q8NA75
RPRKGTLGAMDLGGA

ENTPD2

191

Q9Y5L3
EDSRLLTRGKGAGMP

ISM2

496

Q6H9L7
LGSRYMDLKPLGCGG

MAPK6

16

Q16659
QRKSRGPRGEGGAMS

PEX5

586

P50542
MGARLGRRAGPEAGS

LRRC75B

1

Q2VPJ9
EGETPDRRAGGQMKG

KMT2B

1481

Q9UMN6
PRRMARKGAGDGSDE

MYH9

1931

P35579
LRKDGPLDIRMDGGR

METTL15P1

186

P0C7V9
KGRGSVPTRALGMEG

GLIS2

446

Q9BZE0
MALRKGSFGLPGQGD

PITPNM2

1271

Q9BZ72
KDLAGRLPAGPRGMG

PHB2

6

Q99623
LLRMGGGRLGAPMER

PANK2

121

Q9BZ23
KGRLNRLPAAGVGDM

RPL23

46

P62829
RPLGEGGKMRLAADF

COG5

691

Q9UP83
MAPRKRGGRGISFIF

DAAM1

1

Q9Y4D1
DRKMCPFGRAGLQGR

ADCY1

1071

Q08828
GRGMATKLLARPGTG

FBF1

246

Q8TES7
MAEPGGRGDYRKDGR

FBXL19-AS1

1

Q494R0
IDKLRLFTRGGSGGM

GTPBP10

16

A4D1E9
VGALLGPGAERARMG

CDYL

241

Q9Y232
LYPDGEGGRMTGRGK

COL12A1

1826

Q99715
GCIRGFLLEKGMRGL

GCDH

231

Q92947
ESPMEKGLSGLRGRD

GPAT3

76

Q53EU6
GRVGLQGPKGMRGLE

COL20A1

1126

Q9P218
RGSQGERGKPGLTGM

COL19A1

961

Q14993
ERGKPGLTGMKGAIG

COL19A1

966

Q14993
RGMGLDPQGDRSFLL

DENND11

421

A4D1U4
GGKDGEIPCRRMRSG

DLGAP3

381

O95886
TAMKGDKGDRGERGP

COL7A1

1396

Q02388
VGFMGPRGLKGERGV

COL7A1

2616

Q02388
DQRGLPMDGRGGRDS

CSTF2T

401

Q9H0L4
DRGPKGERGMDGASI

COL15A1

771

P39059
MGKAGGGRNEVDPRF

DNAH10

2571

Q8IVF4
EPRLCGGKGGFGSML

SDE2

71

Q6IQ49
GRYDGLVGMFDPKGR

HARS1

361

P12081
GTGRADRSLRGKPME

PWWP3A

111

Q2TAK8
LMFGDAGGGPRKRKL

SMARCAD1

196

Q9H4L7
DAKMAEGARARGPRG

TMEM80

46

Q96HE8
RLDRRGGAGTMGYKD

LIAT1

36

Q6ZQX7
AGLLRALGERVGPGM

PRR20G

86

P0DPQ3
GGRLLLADDMGLGKT

SMARCAL1

451

Q9NZC9
GPRGMDKLIVDGRGK

CCT7

41

Q99832
DALADGGVKMGLPRR

PYCR2

186

Q96C36
EGLMGIGRRPFSQGL

SPG7

681

Q9UQ90
MEPGTGGSRKRLGPR

PPP1R15B

1

Q5SWA1
GKGLRFSRGGMISFD

PMM1

176

Q92871
GPGRVAKIGDFGMAR

ALK

1261

Q9UM73
RDGRPRLKTMKGGTG

ASIC1

201

P78348
EMGTLRRGGRRPAKD

CGN

31

Q9P2M7
GGGLYGIDSMPDLRR

UNC13C

1026

Q8NB66
MGAGATGRAMDGPRL

NGFR

1

P08138
MRRKGISGKGPGAGD

WASH4P

431

A8MWX3
DRGKLDFGSGLPPME

TRPV2

26

Q9Y5S1
MRRKGISGKGPGAGE

WASH3P

416

C4AMC7
MGLLAGGDVAFPRRG

PHOSPHO1

211

Q8TCT1
LEMGLRRAQGPDGGL

NAPRT

166

Q6XQN6
RGMLPGTKTSAREGG

PLEKHH1

291

Q9ULM0
MGGSAGRELDAGRKP

SOCS7

251

O14512
MGKLRPSRGRGFADV

nan

1

Q6ZR54
GMPGARKAAALSGGL

TNK1

571

Q13470
MDGDGGRRDVPGTLM

WNK2

1

Q9Y3S1
SQFFGLMGKRVGGRP

TAC4

61

Q86UU9
FIPDLGRKGLEGMIR

PLD2

196

O14939
YDRGICPMKGRGLVG

TULP3

281

O75386
GRMLGKGEFGSVREA

TYRO3

521

Q06418
GPKMEGSGGRVRLKA

PRKCZ

6

Q05513